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Yvonne Jones

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X Ray Crystallography

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Min Lu; Mark R Middleton; Indrika Ratnayaka; Victoria Salter; Christian Siebold; Alex Sullivan; Elena V Sviderskaya; Shan Zhong; Caroline Baer; Hilde Breyssens; Nick R Brown; Otavia L Caballero; Jonathan Cebon; Jane Endicott; Colin R Goding; Ying Hu; Thomas John; E Yvonne Jones; Benedikt M Kessler; Stefan Knapp; Xin Lu
Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP.
Christian Siebold; E Yvonne Jones
Structural insights into semaphorins and their receptors.
Guillaume B Stewart-Jones; P Anton van der Merwe; Philippa Easterbrook; E Yvonne Jones; Andrew J McMichael; Sarah L Rowland-Jones; Peter Simpson; Geraldine M Gillespie
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.

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All Publications

2013: Min Lu; Mark R Middleton; Indrika Ratnayaka; Victoria Salter; Christian Siebold; Alex Sullivan; Elena V Sviderskaya; Shan Zhong; Caroline Baer; Hilde Breyssens; Nick R Brown; Otavia L Caballero; Jonathan Cebon; Jane Endicott; Colin R Goding; Ying Hu; Thomas John; E Yvonne Jones; Benedikt M Kessler; Stefan Knapp; Xin Lu
Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP.
Cancer cell 2013;23(5):618-33.
2013: Christian Siebold; E Yvonne Jones
Structural insights into semaphorins and their receptors.
Seminars in cell & developmental biology 2013;24(3):139-45.
2012: Guillaume B Stewart-Jones; P Anton van der Merwe; Philippa Easterbrook; E Yvonne Jones; Andrew J McMichael; Sarah L Rowland-Jones; Peter Simpson; Geraldine M Gillespie
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(50):E3483-92.
2012: Bert J C Janssen; Tomas Malinauskas; Christian Siebold; Greg A Weir; M Zameel Cader; E Yvonne Jones
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.
Nature structural & molecular biology 2012;19(12):1293-9.
2012: Christopher Williams; Oliver J Zaccheo; Matthew Crump; Rosamund Z Ellis; Briony E Forbes; Susana Frago; Frank Grutzner; Hans-Jürgen Hoppe; E Yvonne Jones; Andrew J Mungall; Catherine M Nolan; Stuart N Prince; Dellel Rezgui; Madeleine Strickland; Pakorn Wattana-Amorn; Andrew Bassim Hassan
An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science (New York, N.Y.) 2012;338(6111):1209-13.
2012: Thomas A Bowden; Charlotte H Coles; A Radu Aricescu; Kavitha Baruah; David J Harvey; E Yvonne Jones; Christopher N Scanlan; Byeong Doo Song; David I Stuart; Xiaojie Yu; Max Crispin
Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis.
Journal of the American Chemical Society 2012;134(42):17554-63.
2012: Jean-Marie Bourhis; Jean-Yves Exposito; Karl Harlos; E Yvonne Jones; Natacha Mariano; Catherine Moali; Yuguang Zhao; Nushin Aghajari; David J S Hulmes
Structural basis of fibrillar collagen trimerization and related genetic disorders.
Nature structural & molecular biology 2012;19(10):1031-6.
2011: Shuo Chen; Xi He; A Radu Aricescu; Doryen Bubeck; Wen-Xue Liang; Oscar Llorca; Bryan T MacDonald; Tomas Malinauskas; Jian-Hua Mao; Christian Siebold; E Yvonne Jones
Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling.
Developmental cell 2011;21(5):848-61.
2011: Christian H Bell; E Yvonne Jones; A Radu Aricescu; Christian Siebold
A dual binding mode for RhoGTPases in plexin signalling.
PLoS biology 2011;9(8):e1001134.
2011: Tomas Malinauskas; Christian Siebold; A Radu Aricescu; Weixian Lu; E Yvonne Jones
Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1.
Nature structural & molecular biology 2011;18(8):886-93.
2011: Thomas A Bowden; E Yvonne Jones; David I Stuart
Cells under siege: viral glycoprotein interactions at the cell surface.
Journal of structural biology 2011;175(2):120-6.
2011: Róisín M McMahon; Lone Friis; Christian Siebold; Manuel A Friese; Lars Fugger; E Yvonne Jones
Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 5):447-54.
2011: Doryen Bubeck; Martin A M Reijns; Stephen C Graham; Katy R Astell; E Yvonne Jones; Andrew P Jackson
PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic acids research 2011;39(9):3652-66.
2011: Charlotte H Coles; Yingjie Shen; Alan P Tenney; Christian Siebold; Geoffrey C Sutton; Weixian Lu; John T Gallagher; E Yvonne Jones; John G Flanagan; A Radu Aricescu
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension.
Science (New York, N.Y.) 2011;332(6028):484-8.
2011: Martin A M Reijns; Doryen Bubeck; Lucien C D Gibson; Stephen C Graham; George S Baillie; E Yvonne Jones; Andrew P Jackson
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease.
The Journal of biological chemistry 2011;286(12):10530-9.
2010: Andrew J McMichael; E Yvonne Jones
Genetics. First-class control of HIV-1.
Science (New York, N.Y.) 2010;330(6010):1488-90.
2010: Bert J C Janssen; Ross A Robinson; Francesc Pérez-Brangulí; Christian H Bell; Kevin J Mitchell; Christian Siebold; E Yvonne Jones
Structural basis of semaphorin-plexin signalling.
Nature 2010;467(7319):1118-22.
2010: Thomas A Bowden; Max Crispin; E Yvonne Jones; David I Stuart
Shared paramyxoviral glycoprotein architecture is adapted for diverse attachment strategies.
Biochemical Society transactions 2010;38(5):1349-55.
2010: Gijs I van Boxel; Samantha Holmes; Lars Fugger; E Yvonne Jones
An alternative conformation of the T-cell receptor alpha constant region.
Journal of molecular biology 2010;400(4):828-37.
2010: Thomas A Bowden; Max Crispin; David Harvey; E Yvonne Jones; David I Stuart
Dimeric architecture of the Hendra virus attachment glycoprotein: evidence for a conserved mode of assembly.
Journal of virology 2010;84(12):6208-17.
2010: Elena Seiradake; Karl Harlos; Geoff Sutton; A Radu Aricescu; E Yvonne Jones
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
Nature structural & molecular biology 2010;17(4):398-402.
2010: Ji-Li Chen; Anthony J Morgan; Guillaume Stewart-Jones; Dawn Shepherd; Giovanna Bossi; Linda Wooldridge; Sarah L Hutchinson; Andrew K Sewell; Gillian M Griffiths; Philip van der Merwe; E Yvonne Jones; Antony Galione; Vincenzo Cerundolo
Ca2+ release from the endoplasmic reticulum of NY-ESO-1-specific T cells is modulated by the affinity of TCR and by the use of the CD8 coreceptor.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):1829-39.
2010: Isabel K Macdonald; Maria Harkiolaki; Lawrence Hunt; Timothy Connelley; A Victoria Carroll; Niall D MacHugh; Simon P Graham; E Yvonne Jones; W Ivan Morrison; Darren R Flower; Shirley A Ellis
MHC class I bound to an immunodominant Theileria parva epitope demonstrates unconventional presentation to T cell receptors.
PLoS pathogens 2010;6(10):e1001149.
2009: James Brown; E Yvonne Jones; Briony E Forbes
Keeping IGF-II under control: lessons from the IGF-II-IGF2R crystal structure.
Trends in biochemical sciences 2009;34(12):612-9.
2009: Gijs I van Boxel; Guillaume Stewart-Jones; Samantha Holmes; Sarah Sainsbury; Dawn Shepherd; G M A Gillespie; Karl Harlos; David I Stuart; Ray Owens; E Yvonne Jones
Some lessons from the systematic production and structural analysis of soluble (alpha)(beta) T-cell receptors.
Journal of immunological methods 2009;350(1-2):14-21.
2009: Thomas A Bowden; A Radu Aricescu; Joanne E Nettleship; Christian Siebold; Nahid Rahman-Huq; Raymond J Owens; David I Stuart; E Yvonne Jones
Structural plasticity of eph receptor A4 facilitates cross-class ephrin signaling.
Structure (London, England : 1993) 2009;17(10):1386-97.
2009: Amber Clayton; Christian Siebold; Robert J C Gilbert; Geoffrey C Sutton; Karl Harlos; R A Jeffrey McIlhinney; E Yvonne Jones; A Radu Aricescu
Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors.
Journal of molecular biology 2009;392(5):1125-32.
2009: Max Crispin; Veronica T Chang; David Harvey; Raymond A Dwek; Edward J Evans; David I Stuart; E Yvonne Jones; J Michael Lord; Robert Spooner; Simon J Davis
A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus.
The Journal of biological chemistry 2009;284(32):21684-95.
2009: Thomas A Bowden; Max Crispin; Stephen C Graham; David Harvey; Jonathan M Grimes; E Yvonne Jones; David I Stuart
Unusual molecular architecture of the machupo virus attachment glycoprotein.
Journal of virology 2009;83(16):8259-65.
2009: Benjamin Bishop; A Radu Aricescu; Karl Harlos; Chris A O'Callaghan; E Yvonne Jones; Christian Siebold
Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.
Nature structural & molecular biology 2009;16(7):698-703.
2009: Maria Harkiolaki; Theodora Tsirka; Marc Lewitzky; Philip C Simister; Dhira Joshi; Louise Bird; E Yvonne Jones; Nicola O'Reilly; Stephan M Feller
Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2.
Structure (London, England : 1993) 2009;17(6):809-22.
2009: Stefan Tenzer; Edmund Wee; Anne Burgevin; Guillaume Stewart-Jones; Lone Friis; Kasper Lamberth; Chih-hao Chang; Mikkel Harndahl; Mirjana Weimershaus; Jan Gerstoft; Nadja Akkad; Paul Klenerman; Lars Fugger; E Yvonne Jones; Andrew J McMichael; Søren Buus; Hansjörg Schild; Peter van Endert; Astrid K N Iversen
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance.
Nature immunology 2009;10(6):636-46.
2009: Brandon L Walter; Andrew E Armitage; Stephen C Graham; Tulio de Oliveira; Peter Skinhøj; E Yvonne Jones; David I Stuart; Andrew J McMichael; Bruce Chesebro; Astrid Kn Iversen
Functional characteristics of HIV-1 subtype C compatible with increased heterosexual transmissibility.
AIDS (London, England) 2009;23(9):1047-57.
2009: Max Crispin; Thomas A Bowden; Charlotte H Coles; Karl Harlos; A Radu Aricescu; David Harvey; David I Stuart; E Yvonne Jones
Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions.
Journal of molecular biology 2009;387(5):1061-6.
2009: Guillaume Stewart-Jones; Andreas Wadle; Anja Hombach; Eugene Shenderov; Gerhard Held; Eliane Fischer; Sascha Kleber; Natko Nuber; Frank Stenner-Liewen; Stefan Bauer; Andrew McMichael; Alexander Knuth; Hinrich Abken; Andreas A Hombach; Vincenzo Cerundolo; E Yvonne Jones; Christoph Renner
Rational development of high-affinity T-cell receptor-like antibodies.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5784-8.
2009: Dellel Rezgui; Christopher Williams; Sharon A Savage; Stuart N Prince; Oliver J Zaccheo; E Yvonne Jones; Matthew P Crump; Andrew Bassim Hassan
Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth.
Journal of molecular endocrinology 2009;42(4):341-56.
2009: Maria Harkiolaki; Samantha L Holmes; Pia Svendsen; Jon W Gregersen; Lise T Jensen; Roisin McMahon; Manuel A Friese; Gijs van Boxel; Ruth Etzensperger; John S Tzartos; Kamil Kranc; Sarah Sainsbury; Karl Harlos; Elizabeth D Mellins; Jackie Palace; Margaret M Esiri; Philip van der Merwe; E Yvonne Jones; Lars Fugger
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.
Immunity 2009;30(3):348-57.
2009: James Brown; E Yvonne Jones; Briony E Forbes
Interactions of IGF-II with the IGF2R/cation-independent mannose-6-phosphate receptor mechanism and biological outcomes.
Vitamins and hormones 2009;80():699-719.
2008: Thomas A Bowden; Max Crispin; David Harvey; A Radu Aricescu; Jonathan M Grimes; E Yvonne Jones; David I Stuart
Crystal structure and carbohydrate analysis of Nipah virus attachment glycoprotein: a template for antiviral and vaccine design.
Journal of virology 2008;82(23):11628-36.
2008: Manuel A Friese; Karen B Jakobsen; Lone Friis; Ruth Etzensperger; Matthew J Craner; Róisín M McMahon; Lise T Jensen; Véronique Huygelen; E Yvonne Jones; John I Bell; Lars Fugger
Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.
Nature medicine 2008;14(11):1227-35.
2008: Ruth Etzensperger; Róisín M McMahon; E Yvonne Jones; Lars Fugger
Dissection of the multiple sclerosis associated DR2 haplotype.
Journal of autoimmunity 2008;31(3):201-7.
2008: Thomas A Bowden; A Radu Aricescu; Robert J C Gilbert; Jonathan M Grimes; E Yvonne Jones; David I Stuart
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2.
Nature structural & molecular biology 2008;15(6):567-72.
2008: Jonathan Silk; Mariolina Salio; Gopal R Bommineni; Dawn Shepherd; Uzi Gileadi; James Brown; S Hajar Masri; Paolo Polzella; Gerd Ritter; Gurdyal S Besra; E Yvonne Jones; Richard R Schmidt; Vincenzo Cerundolo
Cutting edge: nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6452-6.
2008: A Radu Aricescu; Christian Siebold; E Yvonne Jones
Receptor protein tyrosine phosphatase micro: measuring where to stick.
Biochemical Society transactions 2008;36(Pt 2):167-72.
2008: Lydia Tabernero; A Radu Aricescu; E Yvonne Jones; Stefan E Szedlacsek
Protein tyrosine phosphatases: structure-function relationships.
The FEBS journal 2008;275(5):867-82.
2008: Jeffrey Ishizuka; Guillaume Stewart-Jones; Philip van der Merwe; John I Bell; Andrew J McMichael; E Yvonne Jones
The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain.
Immunity 2008;28(2):171-82.
2008: Ross Alexander Robinson; Xin Lu; E Yvonne Jones; Christian Siebold
Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73.
Structure (London, England : 1993) 2008;16(2):259-68.
2008: James Brown; Carlie Delaine; Oliver J Zaccheo; Christian Siebold; Robert J C Gilbert; Gijs van Boxel; Adam Denley; John C Wallace; Andrew Bassim Hassan; Briony E Forbes; E Yvonne Jones
Structure and functional analysis of the IGF-II/IGF2R interaction.
The EMBO journal 2008;27(1):265-76.
2008: Jonathan Silk; Mariolina Salio; James Brown; E Yvonne Jones; Vincenzo Cerundolo
Structural and functional aspects of lipid binding by CD1 molecules.
Annual review of cell and developmental biology 2008;24():369-95.
2007: Michael Koch; Simon Camp; Trevor Collen; David Avila; Jan Salomonsen; Hans-Joachim Wallny; Andrew van Hateren; Lawrence Hunt; Jansen P Jacob; Fiona Johnston; Denise Anne Marston; Iain Shaw; P Rod Dunbar; Vincenzo Cerundolo; E Yvonne Jones; Jim Kaufman
Structures of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding.
Immunity 2007;27(6):885-99.
2007: A Radu Aricescu; E Yvonne Jones
Immunoglobulin superfamily cell adhesion molecules: zippers and signals.
Current opinion in cell biology 2007;19(5):543-50.
2007: E Yvonne Jones; Mariolina Salio; Vincenzo Cerundolo
T cell receptors get back to basics.
Nature immunology 2007;8(10):1033-5.
2007: Victoria S Stronge; Mariolina Salio; E Yvonne Jones; Vincenzo Cerundolo
A closer look at CD1d molecules: new horizons in studying NKT cells.
Trends in immunology 2007;28(10):455-62.
2007: A Radu Aricescu; Christian Siebold; Kaushik Choudhuri; Veronica T Chang; Weixian Lu; Simon J Davis; Philip van der Merwe; E Yvonne Jones
Structure of a tyrosine phosphatase adhesive interaction reveals a spacer-clamp mechanism.
Science (New York, N.Y.) 2007;317(5842):1217-20.
2007: Carlie Delaine; Clair L Alvino; Kerrie A McNeil; Terrence D Mulhern; Lisbeth Gauguin; Pierre De Meyts; E Yvonne Jones; James Brown; John C Wallace; Briony E Forbes
A novel binding site for the human insulin-like growth factor-II (IGF-II)/mannose 6-phosphate receptor on IGF-II.
The Journal of biological chemistry 2007;282(26):18886-94.
2007: James Brown; Chris A O'Callaghan; Andrew S J Marshall; Robert J C Gilbert; Christian Siebold; Siamon Gordon; Gordon D Brown; E Yvonne Jones
Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function.
Protein science : a publication of the Protein Society 2007;16(6):1042-52.
2007: Max Crispin; A Radu Aricescu; Veronica T Chang; E Yvonne Jones; David I Stuart; Raymond A Dwek; Simon J Davis; David Harvey
Disruption of alpha-mannosidase processing induces non-canonical hybrid-type glycosylation.
FEBS letters 2007;581(10):1963-8.
2007: Corinna McCarthy; Dawn Shepherd; Sebastian Fleire; Victoria S Stronge; Michael Koch; Petr A Illarionov; Giovanna Bossi; Mariolina Salio; Galit Denkberg; Faye Reddington; Andrea Tarlton; Gopal R Bommineni; Richard R Schmidt; Yoram Reiter; Gillian M Griffiths; Philip van der Merwe; Gurdyal S Besra; E Yvonne Jones; Facundo D Batista; Vincenzo Cerundolo
The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation.
The Journal of experimental medicine 2007;204(5):1131-44.
2007: Pojchong Chotiyarnwong; Guillaume Stewart-Jones; Michael J Tarry; Wanwisa Dejnirattisai; Christian Siebold; Michael Koch; David I Stuart; Karl Harlos; Prida Malasit; Gavin Screaton; Juthathip Mongkolsapaya; E Yvonne Jones
Humidity control as a strategy for lattice optimization applied to crystals of HLA-A*1101 complexed with variant peptides from dengue virus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 5):386-92.
2007: Max Crispin; David I Stuart; E Yvonne Jones
Building meaningful models of glycoproteins.
Nature structural & molecular biology 2007;14(5):354; discussion 354-5.
2007: Rishi Matadeen; Wai-Ching Hon; John Heath; E Yvonne Jones; Stephen Fuller
The dynamics of signal triggering in a gp130-receptor complex.
Structure (London, England : 1993) 2007;15(4):441-8.
2007: Veronica T Chang; Max Crispin; A Radu Aricescu; David Harvey; Joanne E Nettleship; Janet A Fennelly; Chao Yu; Kent S Boles; Edward J Evans; David I Stuart; Raymond A Dwek; E Yvonne Jones; Raymond J Owens; Simon J Davis
Glycoprotein structural genomics: solving the glycosylation problem.
Structure (London, England : 1993) 2007;15(3):267-73.
2007: Nathan R Zaccai; Andrew P May; Robert Robinson; Leslie D Burtnick; Paul R Crocker; Reinhard Brossmer; Soerge Kelm; E Yvonne Jones
Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin.
Journal of molecular biology 2007;365(5):1469-79.
2006: Maria Harkiolaki; Robert J C Gilbert; E Yvonne Jones; Stephan M Feller
The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal.
Structure (London, England : 1993) 2006;14(12):1741-53.
2006: Christopher Hourigan; Maria Harkiolaki; Neil A Peterson; John I Bell; E Yvonne Jones; Christopher A O'Callaghan
The structure of the human allo-ligand HLA-B*3501 in complex with a cytochrome p450 peptide: steric hindrance influences TCR allo-recognition.
European journal of immunology 2006;36(12):3288-93.
2006: A Radu Aricescu; Weixian Lu; E Yvonne Jones
A time- and cost-efficient system for high-level protein production in mammalian cells.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1243-50.
2006: L Banci; I Bertini; S Cusack; R N de Jong; U Heinemann; E Yvonne Jones; F Kozielski; K Maskos; Albrecht Messerschmidt; R Owens; Anastassis Perraks; Arnaud Poterszman; G Schneider; Christian Siebold; I Silman; Titia K Sixma; Guillaume Stewart-Jones; Joel Sussman; Jean-Claude Thierry; Dino Moras
First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1208-17.
2006: A Radu Aricescu; Rene Assenberg; Roslyn M Bill; Didier Busso; Veronica T Chang; Simon J Davis; A Dubrovsky; L Gustafsson; Kristina Hedfalk; U Heinemann; I M Jones; D Ksiazek; C Lang; K Maskos; Albrecht Messerschmidt; Sofia Macieira; Yoav Peleg; Anastassis Perraks; Arnaud Poterszman; G Schneider; Titia K Sixma; Joel Sussman; G Sutton; N Tarboureich; Tzviya Zeev-Ben-Mordehai; E Yvonne Jones
Eukaryotic expression: developments for structural proteomics.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1114-24.
2006: Edward J Evans; Mónica A A Castro; Ronan O'Brien; Alice Kearney; Heather Walsh; Lisa M Sparks; Michael G Tucknott; Elizabeth A Davies; Alexandre M Carmo; Philip van der Merwe; David I Stuart; E Yvonne Jones; John E Ladbury; Shinji Ikemizu; Simon J Davis
Crystal structure and binding properties of the CD2 and CD244 (2B4)-binding protein, CD48.
The Journal of biological chemistry 2006;281(39):29309-20.
2006: Geraldine M A Gillespie; Guillaume Stewart-Jones; Jaya Rengasamy; Tara Beattie; Job J Bwayo; Francis A Plummer; Rupert Kaul; Andrew J McMichael; Philippa Easterbrook; Tao Dong; E Yvonne Jones; Sarah L Rowland-Jones
Strong TCR conservation and altered T cell cross-reactivity characterize a B*57-restricted immune response in HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3893-902.
2006: Philippe Roche; James Brown; Adam Denley; Briony E Forbes; John C Wallace; E Yvonne Jones; Robert M Esnouf
Computational model for the IGF-II/IGF2r complex that is predictive of mutational and surface plasmon resonance data.
Proteins 2006;64(3):758-68.
2006: Max Crispin; David Harvey; Veronica T Chang; Chao Yu; A Radu Aricescu; E Yvonne Jones; Simon J Davis; Raymond A Dwek; Pauline M Rudd
Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway.
Glycobiology 2006;16(8):748-56.
2006: Oliver J Zaccheo; Stuart N Prince; David M Miller; Christopher Williams; C Fred Kemp; James Brown; E Yvonne Jones; Lucy E Catto; Matthew Crump; Andrew Bassim Hassan
Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues.
Journal of molecular biology 2006;359(2):403-21.
2006: Ann Glithero; Jose Tormo; Klaus Doering; Mayumi Kojima; E Yvonne Jones; Tim Elliott
The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate.
The Journal of biological chemistry 2006;281(18):12699-704.
2006: E Yvonne Jones; Lars Fugger; Jack L Strominger; Christian Siebold
MHC class II proteins and disease: a structural perspective.
Nature reviews. Immunology 2006;6(4):271-82.
2006: Stephan D Gadola; Michael Koch; Jon Marles-Wright; Nikolai M Lissin; Dawn Shepherd; Gediminas Matulis; Karl Harlos; Peter M Villiger; David I Stuart; Bent K Jakobsen; Vincenzo Cerundolo; E Yvonne Jones
Structure and binding kinetics of three different human CD1d-alpha-galactosylceramide-specific T cell receptors.
The Journal of experimental medicine 2006;203(3):699-710.
2006: A Radu Aricescu; Wai-Ching Hon; Christian Siebold; Weixian Lu; Philip van der Merwe; E Yvonne Jones
Molecular analysis of receptor protein tyrosine phosphatase mu-mediated cell adhesion.
The EMBO journal 2006;25(4):701-12.
2006: Astrid K N Iversen; Guillaume Stewart-Jones; Gerald Learn; Natasha Christie; Christina Sylvester-Hviid; Andrew E Armitage; Rupert Kaul; Tara Beattie; Jean K Lee; Yanping Li; Pojchong Chotiyarnwong; Tao Dong; Xiaoning Xu; Mark A Luscher; Kelly MacDonald; Henrik Ullum; Bente Klarlund Pedersen; Peter Skinhøj; Lars Fugger; Soren Buus; James I Mullins; E Yvonne Jones; Philip van der Merwe; Andrew J McMichael
Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope.
Nature immunology 2006;7(2):179-89.
2006: Robert M Esnouf; Christopher A Love; Karl Harlos; David I Stuart; E Yvonne Jones
Structure determination of human semaphorin 4D as an example of the use of MAD in non-optimal cases.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 1):108-15.
2005: Clive J Petry; Ken K Ong; Dianne L Wingate; James Brown; Carolyn D Scott; E Yvonne Jones; Marcus E Pembrey; David D Dunger
Genetic variation in the type 2 insulin-like growth factor receptor gene and disparity in childhood height.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2005;15(6):363-8.
2005: Christian Siebold; Nick S Berrow; thomas walter; Karl Harlos; Raymond J Owens; David I Stuart; Jonathan R Terman; Alex L Kolodkin; R Jeroen Pasterkamp; E Yvonne Jones
High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16836-41.
2005: Manuel A Friese; E Yvonne Jones; Lars Fugger
MHC II molecules in inflammatory diseases: interplay of qualities and quantities.
Trends in immunology 2005;26(11):559-61.
2005: Chrystelle Lamagna; Paolo Meda; Guillaume Mandicourt; James Brown; Robert J C Gilbert; E Yvonne Jones; Friedemann Kiefer; Pilar Ruga; Beat A Imhof; michel AURRAND-LIONS
Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion.
Molecular biology of the cell 2005;16(10):4992-5003.
2005: Gustavo Sajnani; A Radu Aricescu; E Yvonne Jones; John Gallagher; Daniel Alete; Andrew W Stoker
PTPsigma promotes retinal neurite outgrowth non-cell-autonomously.
Journal of neurobiology 2005;65(1):59-71.
2005: Guillaume Stewart-Jones; Geraldine Gillespie; Ian M Overton; Rupert Kaul; Philippe Roche; Andrew J McMichael; Sarah Rowland-Jones; E Yvonne Jones
Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2459-68.
2005: Michael Koch; Victoria S Stronge; Dawn Shepherd; Stephan D Gadola; Bini Mathew; Gerd Ritter; Alan Fersht; Gurdyal S Besra; Richard R Schmidt; E Yvonne Jones; Vincenzo Cerundolo
The crystal structure of human CD1d with and without alpha-galactosylceramide.
Nature immunology 2005;6(8):819-26.
2005: thomas walter; Jonathan M Diprose; Chris J Mayo; Christian Siebold; Mike G Pickford; Lester Carter; Geoffrey C Sutton; Nick S Berrow; James Brown; Ian M Berry; Guillaume Stewart-Jones; Jonathan M Grimes; David K Stammers; Robert M Esnouf; E Yvonne Jones; Raymond J Owens; David I Stuart; Karl Harlos
A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 6):651-7.
2005: Ji-Li Chen; Guillaume Stewart-Jones; Giovanna Bossi; Nikolai M Lissin; Linda Wooldridge; Ed Man-Lik Choi; Gerhard Held; P Rod Dunbar; Robert M Esnouf; malkit sami; Jonathan M Boulter; Pierre J Rizkallah; Christoph Renner; Andrew Sewell; Philip van der Merwe; Bent K Jakobsen; Gillian Griffiths; E Yvonne Jones; Vincenzo Cerundolo
Structural and kinetic basis for heightened immunogenicity of T cell vaccines.
The Journal of experimental medicine 2005;201(8):1243-55.
2005: E Yvonne Jones
Favorite flavors of surfaces.
Nature immunology 2005;6(4):365-6.
2005: Samantha Holmes; Manuel A Friese; Christian Siebold; E Yvonne Jones; John Bell; Lars Fugger
Multiple sclerosis: MHC associations and therapeutic implications.
Expert reviews in molecular medicine 2005;7(3):1-17.
2005: Christopher J Mayo; Jonathan M Diprose; thomas walter; Ian M Berry; Julie Wilson; Raymond J Owens; E Yvonne Jones; Karl Harlos; David I Stuart; Robert M Esnouf
Benefits of automated crystallization plate tracking, imaging, and analysis.
Structure (London, England : 1993) 2005;13(2):175-82.
2005: Guillaume Stewart-Jones; katalin di gleria; Simon Kollnberger; Andrew J McMichael; E Yvonne Jones; Paul Bowness
Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B*2705.
European journal of immunology 2005;35(2):341-51.
2004: Tao Dong; Guillaume Stewart-Jones; Nan Chen; Philippa Easterbrook; Xiaoning Xu; Laura Papagno; Victor Appay; Michael Weekes; Christopher Conlon; Celsa A Spina; Susan Little; Gavin Screaton; Philip van der Merwe; Douglas D Richman; Andrew J McMichael; E Yvonne Jones; Sarah L Rowland-Jones
HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor.
The Journal of experimental medicine 2004;200(12):1547-57.
2004: Jean K Lee; Guillaume Stewart-Jones; Tao Dong; Karl Harlos; katalin di gleria; Lucy Dorrell; Daniel C Douek; Philip van der Merwe; E Yvonne Jones; Andrew J McMichael
T cell cross-reactivity and conformational changes during TCR engagement.
The Journal of experimental medicine 2004;200(11):1455-66.
2004: Ermanno Gherardi; Christopher A Love; Robert M Esnouf; E Yvonne Jones
The sema domain.
Current opinion in structural biology 2004;14(6):669-78.
2004: Marc Lewitzky; Maria Harkiolaki; Marie-Charlotte Domart; E Yvonne Jones; Stephan M Feller
Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix.
The Journal of biological chemistry 2004;279(27):28724-32.
2004: Christian Siebold; Bjarke E Hansen; Jessica R Wyer; Karl Harlos; Robert E Esnouf; Arne Svejgaard; John I Bell; Jack L Strominger; E Yvonne Jones; Lars Fugger
Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1999-2004.
2004: Thil Batuwangala; Dawn Shepherd; Stephan D Gadola; Kevin J C Gibson; Nathan R Zaccai; Alan Fersht; Gurdyal S Besra; Vincenzo Cerundolo; E Yvonne Jones
The crystal structure of human CD1b with a bound bacterial glycolipid.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2382-8.
2004: Thil Batuwangala; Mireille Leduc; Jonathan M Gibbins; Cassian Bon; E Yvonne Jones
Structure of the snake-venom toxin convulxin.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 1):46-53.
2003: Maxine Allen; Andrea Heinzmann; Emiko Noguchi; Goncalo Abecasis; John Broxholme; Chris P Ponting; Sumit Bhattacharyya; Jon Tinsley; Youming Zhang; Richard Holt; E Yvonne Jones; Nicholas J Lench; Alisoun Carey; Helene Jones; Nicholas J Dickens; Claire Dimon; Rosie Nicholls; Crystal Baker; Luzheng Xue; Elizabeth Townsend; Michael Kabesch; Stephan K Weiland; David Carr; Erika von Mutius; Ian M Adcock; Peter J Barnes; G Mark Lathrop; Mark Edwards; Miriam F Moffatt; William O C M Cookson
Positional cloning of a novel gene influencing asthma from chromosome 2q14.
Nature genetics 2003;35(3):258-63.
2003: Caroline Moreau-Fauvarque; Atsushi Kumanogoh; Emeline Camand; Céline Jaillard; Gilles Barbin; Isabelle Boquet; Christopher Love; E Yvonne Jones; Hitoshi Kikutani; Catherine Lubetzki; Isabelle Dusart; Alain Chédotal
The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(27):9229-39.
2003: Christopher A Love; Karl Harlos; Nasim Mavaddat; Simon J Davis; David I Stuart; E Yvonne Jones; Robert M Esnouf
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D.
Nature structural biology 2003;10(10):843-8.
2003: Mitsunori Shiroishi; Kouhei Tsumoto; Kimie Amano; Yasuo Shirakihara; Marco COLONna; Veronique M Braud; David S J Allan; Azure Makadzange; Sarah Rowland-Jones; Benjamin E Willcox; E Yvonne Jones; Philip van der Merwe; Izumi Kumagai; Katsumi Maenaka
Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8856-61.
2003: Guillaume Stewart-Jones; Andrew J McMichael; John I Bell; David I Stuart; E Yvonne Jones
A structural basis for immunodominant human T cell receptor recognition.
Nature immunology 2003;4(7):657-63.
2003: Maria Harkiolaki; Marc Lewitzky; Robert J C Gilbert; E Yvonne Jones; Roland P Bourette; Guy Mouchiroud; Holger Sondermann; Ismail Moarefi; Stephan M Feller
Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76.
The EMBO journal 2003;22(11):2571-82.
2003: Stephan D Gadola; Anastasios Karadimitris; Nathan R Zaccai; Mariolina Salio; Nicolas Dulphy; Dawn Shepherd; E Yvonne Jones; Vincenzo Cerundolo
Generation of CD1 tetramers as a tool to monitor glycolipid-specific T cells.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2003;358(1433):875-7.
2003: Nathan R Zaccai; Katsumi Maenaka; Taeko Maenaka; Paul R Crocker; Reinhard Brossmer; Soerge Kelm; E Yvonne Jones
Structure-guided design of sialic acid-based Siglec inhibitors and crystallographic analysis in complex with sialoadhesin.
Structure (London, England : 1993) 2003;11(5):557-67.
2003: Chris A O'Callaghan; E Yvonne Jones
Structural and energetic aspects of multispecific immune recognition by NKG2D.
Structure (London, England : 1993) 2003;11(4):360-1.
2002: Heather L E Lang; Helle Jacobsen; Shinji Ikemizu; Christina Andersson; Karl Harlos; Lars Madsen; Peter Hjorth; Leif Sondergaard; Arne Svejgaard; Kai W Wucherpfennig; David I Stuart; John I Bell; E Yvonne Jones; Lars Fugger
A functional and structural basis for TCR cross-reactivity in multiple sclerosis.
Nature immunology 2002;3(10):940-3.
2002: Stephan D Gadola; Nathan R Zaccai; Karl Harlos; Dawn Shepherd; Julio C Castro-Palomino; Gerd Ritter; Richard R Schmidt; E Yvonne Jones; Vincenzo Cerundolo
Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nature immunology 2002;3(8):721-6.
2002: Wai-Ching Hon; Michael I Wilson; Karl Harlos; Timothy D W Claridge; Christopher J Schofield; Christopher W Pugh; Patrick H Maxwell; Peter J Ratcliffe; David I Stuart; E Yvonne Jones
Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.
Nature 2002;417(6892):975-8.
2002: James Brown; Robert M Esnouf; Margaret A Jones; Jane Linnell; Karl Harlos; Andrew Bassim Hassan; E Yvonne Jones
Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur.
The EMBO journal 2002;21(5):1054-62.
2002: Rosemary J Boyton; Nathan R Zaccai; E Yvonne Jones; Daniel M Altmann
CD4 T cells selected by antigen under Th2 polarizing conditions favor an elongated TCR alpha chain complementarity-determining region 3.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1018-27.
2001: Andrew J Walley; Stéphane Chavanas; Miriam F Moffatt; R M Esnouf; B Ubhi; R Lawrence; K Wong; Goncalo Abecasis; E Yvonne Jones; John I Harper; Alain Hovnanian; William O C M Cookson
Gene polymorphism in Netherton and common atopic disease.
Nature genetics 2001;29(2):175-8.
2001: Lucy Dorrell; Benjamin E Willcox; E Yvonne Jones; Geraldine Gillespie; Harr F Njai; Saihou Sabally; Assan Jaye; K DeGleria; Tim Rostron; E Lepin; Andrew McMichael; Hilton Whittle; Sarah Rowland-Jones
Cytotoxic T lymphocytes recognize structurally diverse, clade-specific and cross-reactive peptides in human immunodeficiency virus type-1 gag through HLA-B53.
European journal of immunology 2001;31(6):1747-56.
2001: Simon J Davis; Shinji Ikemizu; Alison V Collins; Janet A Fennelly; Karl Harlos; E Yvonne Jones; David I Stuart
Crystallization and functional analysis of a soluble deglycosylated form of the human costimulatory molecule B7-1.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 4):605-8.
2001: Sabrina Tafuro; UC Meier; P Rod Dunbar; E Yvonne Jones; G T Layton; M G Hunter; John I Bell; Andrew J McMichael
Reconstitution of antigen presentation in HLA class I-negative cancer cells with peptide-beta2m fusion molecules.
European journal of immunology 2001;31(2):440-9.
2000: E Yvonne Jones
The tumour necrosis factor receptor family: life or death choices.
Current opinion in structural biology 2000;10(6):644-8.
2000: Katsumi Maenaka; Taeko Maenaka; H Tomiyama; M Takiguchi; David I Stuart; E Yvonne Jones
Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3260-7.
2000: M C Deller; K R Hudson; S Ikemizu; J Bravo; E Yvonne Jones; John Heath
Crystal structure and functional dissection of the cytostatic cytokine oncostatin M.
Structure (London, England : 1993) 2000;8(8):863-74.
2000: P Krausa; C Münz; W Keilholz; S Stevanovic; E Yvonne Jones; M Browning; Mike Bunce; H G Rammensee; Andrew McMichael
Definition of peptide binding motifs amongst the HLA-A*30 allelic group.
Tissue antigens 2000;56(1):10-8.
2000: George F Gao; Benjamin E Willcox; Jessica R Wyer; Jonathan M Boulter; Christopher A O'Callaghan; Katsumi Maenaka; David I Stuart; E Yvonne Jones; Philip van der Merwe; John I Bell; Bent K Jakobsen
Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha.
The Journal of biological chemistry 2000;275(20):15232-8.
2000: Shinji Ikemizu; Robert J C Gilbert; Janet A Fennelly; Alison V Collins; Karl Harlos; E Yvonne Jones; David I Stuart; Simon J Davis
Structure and dimerization of a soluble form of B7-1.
Immunity 2000;12(1):51-60.
1999: Robert Robinson; C Radziejewski; G Spraggon; J Greenwald; M R Kostura; Leslie D Burtnick; D I Stuart; Senyon Choe; E Yvonne Jones
The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein science : a publication of the Protein Society 1999;8(12):2589-97.
1999: Katsumi Maenaka; E Yvonne Jones
MHC superfamily structure and the immune system.
Current opinion in structural biology 1999;9(6):745-53.
1999: Benjamin E Willcox; George F Gao; Jessica R Wyer; Christopher A O'Callaghan; Jonathan M Boulter; E Yvonne Jones; Philip van der Merwe; John I Bell; Bent K Jakobsen
Production of soluble alphabeta T-cell receptor heterodimers suitable for biophysical analysis of ligand binding.
Protein science : a publication of the Protein Society 1999;8(11):2418-23.
1999: Juthathip Mongkolsapaya; J M Grimes; N Chen; Xiao-Ning Xu; David I Stuart; E Yvonne Jones; Gavin Screaton
Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation.
Nature structural biology 1999;6(11):1048-53.
1999: Paul Bowness; Nathan R Zaccai; Lucy A Bird; E Yvonne Jones
HLA-B27 and disease pathogenesis: new structural and functional insights.
Expert reviews in molecular medicine 1999;1999():1-10.
1999: Katsumi Maenaka; T Juji; T Nakayama; Jessica R Wyer; George F Gao; Taeko Maenaka; Nathan R Zaccai; A Kikuchi; T Yabe; K Tokunaga; K Tadokoro; David I Stuart; E Yvonne Jones; Philip van der Merwe
Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties.
The Journal of biological chemistry 1999;274(40):28329-34.
1999: Terry D Butters; Lisa M Sparks; Karl Harlos; Shinji Ikemizu; David I Stuart; E Yvonne Jones; Simon J Davis
Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: application to glycoprotein crystallization.
Protein science : a publication of the Protein Society 1999;8(8):1696-701.
1999: K Maenaka; T Juji; David I Stuart; E Yvonne Jones
Crystal structure of the human p58 killer cell inhibitory receptor (KIR2DL3) specific for HLA-Cw3-related MHC class I.
Structure (London, England : 1993) 1999;7(4):391-8.
1999: Shinji Ikemizu; Lisa M Sparks; Philip van der Merwe; Karl Harlos; David I Stuart; E Yvonne Jones; Simon J Davis
Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(8):4289-94.
1999: A Sharma; Janet Askari; M J Humphries; E Yvonne Jones; David I Stuart
Crystal structure of a heparin- and integrin-binding segment of human fibronectin.
The EMBO journal 1999;18(6):1468-79.
1999: Ann Glithero; Jose Tormo; JS Haurum; Gemma Arsequell; Gregorio Valencia; J Edwards; Sebastian Springer; A Townsend; Y L Pao; Mark R Wormald; Raymond A Dwek; E Yvonne Jones; Tim Elliott
Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity.
Immunity 1999;10(1):63-74.
1998: Robert M Esnouf; Jingshan Ren; E F Garman; D O Somers; CK Ross; E Yvonne Jones; David K Stammers; David I Stuart
Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 5):938-53.
1998: Paul Bowness; Rachel Allen; D N Barclay; E Yvonne Jones; Andrew J McMichael
Importance of a conserved TCR J alpha-encoded tyrosine for T cell recognition of an HLA B27/peptide complex.
European journal of immunology 1998;28(9):2704-13.
1998: Jingshan Ren; Robert M Esnouf; Andrew L Hopkins; E Yvonne Jones; I Kirby; J Keeling; CK Ross; B A Larder; David I Stuart; David K Stammers
3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9518-23.
1998: Hiromichi Tanaka; R T Walker; Andrew L Hopkins; Jingshan Ren; E Yvonne Jones; K Fujimoto; M Hayashi; T Miyasaka; Masanori Baba; David K Stammers; David I Stuart
Allosteric inhibitors against HIV-1 reverse transcriptase: design and synthesis of MKC-442 analogues having an omega-functionalized acyclic structure.
Antiviral chemistry & chemotherapy 1998;9(4):325-32.
1998: E Yvonne Jones; J Tormo; S W Reid; David I Stuart
Recognition surfaces of MHC class I.
Immunological reviews 1998;163():121-8.
1998: Simon J Davis; Elizabeth A Davies; M G Tucknott; E Yvonne Jones; Philip van der Merwe
The role of charged residues mediating low affinity protein-protein recognition at the cell surface by CD2.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5490-4.
1998: K Maenaka; T Juji; K Tadokoro; K Harlos; David I Stuart; E Yvonne Jones
Crystallization and preliminary diffraction studies of the extracellular region of human p58 killer cell inhibitory receptor (KIR2).
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 3):433-5.
1998: Christopher A O'Callaghan; Jose Tormo; Benjamin E Willcox; C D Blundell; Bent K Jakobsen; David I Stuart; A J McMichael; John I Bell; E Yvonne Jones
Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E.
Protein science : a publication of the Protein Society 1998;7(5):1264-6.
1998: George F Gao; UC Gerth; Jessica R Wyer; Benjamin E Willcox; Christopher A O'Callaghan; Z Zhang; E Yvonne Jones; John I Bell; Bent K Jakobsen
Assembly and crystallization of the complex between the human T cell coreceptor CD8alpha homodimer and HLA-A2.
Protein science : a publication of the Protein Society 1998;7(5):1245-9.
1998: Andrew P May; Robert Robinson; Mary C Vinson; Paul R Crocker; E Yvonne Jones
Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution.
Molecular cell 1998;1(5):719-28.
1998: Christopher A O'Callaghan; Jose Tormo; Benjamin E Willcox; Veronique M Braud; Bent K Jakobsen; David I Stuart; Andrew J McMichael; John I Bell; E Yvonne Jones
Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Molecular cell 1998;1(4):531-41.
1997: A Sharma; Zihe Rao; Elizabeth Fry; T Booth; E Yvonne Jones; D J Rowlands; D L Simmons; David I Stuart
Specific interactions between human integrin alpha v beta 3 and chimeric hepatitis B virus core particles bearing the receptor-binding epitope of foot-and-mouth disease virus.
Virology 1997;239(1):150-7.
1997: George F Gao; Jose Tormo; UC Gerth; Jessica R Wyer; Andrew J McMichael; David I Stuart; John I Bell; E Yvonne Jones; Bent K Jakobsen
Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.
Nature 1997;387(6633):630-4.
1997: Veronique M Braud; E Yvonne Jones; Andrew McMichael
The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9.
European journal of immunology 1997;27(5):1164-9.
1997: Robert M Esnouf; Jingshan Ren; Andrew L Hopkins; CK Ross; E Yvonne Jones; David K Stammers; David I Stuart
Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3984-9.
1997: Andrew P May; Robert Robinson; Robin T Aplin; P Bradfield; Paul R Crocker; E Yvonne Jones
Expression, crystallization, and preliminary X-ray analysis of a sialic acid-binding fragment of sialoadhesin in the presence and absence of ligand.
Protein science : a publication of the Protein Society 1997;6(3):717-21.
1996: S W Reid; S McAdam; K J Smith; Paul Klenerman; Christopher A O'Callaghan; Karl Harlos; Bent K Jakobsen; Andrew J McMichael; John I Bell; David I Stuart; E Yvonne Jones
Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
The Journal of experimental medicine 1996;184(6):2279-86.
1996: Robert Robinson; Czeslaw Radziejewski; David I Stuart; E Yvonne Jones
Crystals of the neurotrophins.
Protein science : a publication of the Protein Society 1996;5(5):973-7.
1996: M Vinson; Philip van der Merwe; Soerge Kelm; A May; E Yvonne Jones; Paul R Crocker
Characterization of the sialic acid-binding site in sialoadhesin by site-directed mutagenesis.
The Journal of biological chemistry 1996;271(16):9267-72.
1996: Andrew L Hopkins; Jingshan Ren; Robert M Esnouf; Benjamin E Willcox; E Yvonne Jones; C Ross; T Miyasaka; R T Walker; Hiromichi Tanaka; David K Stammers; David I Stuart
Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.
Journal of medicinal chemistry 1996;39(8):1589-600.
1996: S W Reid; K J Smith; Bent K Jakobsen; Christopher A O'Callaghan; H Reyburn; Karl Harlos; David I Stuart; Andrew J McMichael; John I Bell; E Yvonne Jones
Production and crystallization of MHC class I B allele single peptide complexes.
FEBS letters 1996;383(1-2):119-23.
1996: K J Smith; S W Reid; Karl Harlos; Andrew J McMichael; David I Stuart; John I Bell; E Yvonne Jones
Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.
Immunity 1996;4(3):215-28.
1996: K J Smith; S W Reid; David I Stuart; Andrew J McMichael; E Yvonne Jones; John I Bell
An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501.
Immunity 1996;4(3):203-13.
1995: David I Stuart; E Yvonne Jones
Recognition at the cell surface: recent structural insights.
Current opinion in structural biology 1995;5(6):735-43.
1995: Robert Robinson; L M Grey; D Staunton; David I Stuart; J K Heath; E Yvonne Jones
The crystal structure of murine leukemia inhibitory factor.
Annals of the New York Academy of Sciences 1995;762():179-87; discussion 187-8.
1995: G Spraggon; C Phillips; U K Nowak; C P Ponting; D Saunders; Christopher M Dobson; David I Stuart; E Yvonne Jones
The crystal structure of the catalytic domain of human urokinase-type plasminogen activator.
Structure (London, England : 1993) 1995;3(7):681-91.
1995: Robert Robinson; Czeslaw Radziejewski; David I Stuart; E Yvonne Jones
Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer.
Biochemistry 1995;34(13):4139-46.
1995: E Yvonne Jones; Karl Harlos; Matthew J Bottomley; Robert Robinson; Paul C Driscoll; R M Edwards; John M Clements; T J Dudgeon; David I Stuart
Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.
Nature 1995;373(6514):539-44.
1995: Simon J Davis; Elizabeth A Davies; A Neil Barclay; S Daenke; D L Bodian; E Yvonne Jones; David I Stuart; Terry D Butters; Raymond A Dwek; Philip van der Merwe
Ligand binding by the immunoglobulin superfamily recognition molecule CD2 is glycosylation-independent.
The Journal of biological chemistry 1995;270(1):369-75.
1994: Matthew J Bottomley; Robert Robinson; Paul C Driscoll; Karl Harlos; David I Stuart; R T Aplin; John M Clements; E Yvonne Jones; T J Dudgeon
Crystallization and preliminary X-ray diffraction characterisation of both a native and selenomethionyl VLA-4 binding fragment of VCAM-1.
Journal of molecular biology 1994;244(4):464-8.
1994: Karl Harlos; D M Martin; D P O'Brien; E Yvonne Jones; David I Stuart; I Polikarpov; A Miller; E G Tuddenham; C W Boys
Crystal structure of the extracellular region of human tissue factor.
Nature 1994;370(6491):662-6.
1994: D L Bodian; E Yvonne Jones; Karl Harlos; David I Stuart; Simon J Davis
Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.
Structure (London, England : 1993) 1994;2(8):755-66.
1994: Robert Robinson; L M Grey; D Staunton; H Vankelecom; AB Vernallis; J F Moreau; David I Stuart; J K Heath; E Yvonne Jones
The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding.
Cell 1994;77(7):1101-16.
1994: A S Tavernor; Julia H Kydd; D L Bodian; E Yvonne Jones; David I Stuart; Simon J Davis; Geoffrey W Butcher
Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA. Structure-based analysis of conserved sequence elements.
European journal of biochemistry / FEBS 1994;219(3):969-76.
1994: K Ravi Acharya; E F Passalacqua; E Yvonne Jones; Karl Harlos; David I Stuart; R D Brehm; Howard S Tranter
Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxin-1.
Nature 1994;367(6458):94-7.
1993: Simon J Davis; E Yvonne Jones; D L Bodian; A Neil Barclay; Philip van der Merwe
Analysis of the structure and interactions of CD2.
Biochemical Society transactions 1993;21(4):952-8.
1993: David K Stammers; C Delves; S Ballantine; E Yvonne Jones; D I Stuart; A Achari; P K Bryant; J N Champness
Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.
Journal of molecular biology 1993;230(2):679-80.
1993: Simon J Davis; Michael J Puklavec; D A Ashford; Karl Harlos; E Yvonne Jones; David I Stuart; A F Williams
Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2.
Protein engineering 1993;6(2):229-32.
1992: E Yvonne Jones; Simon J Davis; A F Williams; Karl Harlos; David I Stuart
Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2.
Nature 1992;360(6401):232-9.
1992: E Yvonne Jones; David I Stuart; N P Walker
Crystal structure of TNF.
Immunology series 1992;56():93-127.
1991: E Yvonne Jones; N P Walker; David I Stuart
Methodology employed for the structure determination of tumour necrosis factor, a case of high non-crystallographic symmetry.
Acta crystallographica. Section A, Foundations of crystallography 1991;47 ( Pt 6)():753-70.
1991: E Yvonne Jones; A Miller
Analysis of structural design features in collagen.
Journal of molecular biology 1991;218(1):209-19.
1990: E Yvonne Jones; David I Stuart; N P Walker
The three-dimensional structure of tumour necrosis factor.
Progress in clinical and biological research 1990;349():321-7.
1990: E Yvonne Jones; David I Stuart; N P Walker
The structure of tumour necrosis factor--implications for biological function.
Journal of cell science. Supplement 1990;13():11-8.
1989: E Yvonne Jones; David I Stuart; N P Walker
Structure of tumour necrosis factor.
Nature 1989;338(6212):225-8.