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Richard Jope

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Neuroblastoma

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Co-Publications
Name
37
Song, Ling
25
Johnson, Gail
14
Bijur, Gautam
14
De Sarno, Patrizia
11
Li, Xinmin
11
Zmijewska, Anna
8
Li, Xiaohua
5
Beurel, Eléonore
5
Zmijewski, Jaroslaw
5
Roh, Myoung-Sun
4
Lesort, Mathieu
4
King, Taj
4
Grimes, CA
3
Harrell, Lindy
3
Friedman, Ari

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Publications

TOP 3
Sun Mianen; Meares Gordon; Song Ling; Jope Richard S
XIAP associates with GSK3 and inhibits the promotion of intrinsic apoptotic signaling by GSK3.
Eom Tae-Yeon; Jope Richard S
Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3alpha/beta impairs in vivo neural precursor cell proliferation.
Beurel Eléonore; Jope Richard S
Glycogen synthase kinase-3 promotes the synergistic action of interferon-gamma on lipopolysaccharide-induced IL-6 production in RAW264.7 cells.

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All Publications

2009: Sun Mianen; Meares Gordon; Song Ling; Jope Richard S
XIAP associates with GSK3 and inhibits the promotion of intrinsic apoptotic signaling by GSK3.
Cellular signalling 2009;21(12):1857-65.
2009: Eom Tae-Yeon; Jope Richard S
Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3alpha/beta impairs in vivo neural precursor cell proliferation.
Biological psychiatry 2009;66(5):494-502.
2009: Beurel Eléonore; Jope Richard S
Glycogen synthase kinase-3 promotes the synergistic action of interferon-gamma on lipopolysaccharide-induced IL-6 production in RAW264.7 cells.
Cellular signalling 2009;21(6):978-85.
2009: Yuskaitis Christopher J; Jope Richard S
Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity.
Cellular signalling 2009;21(2):264-73.
2009: Min Wenzhong William; Yuskaitis Christopher J; Yan Qijiang; Sikorski Christopher; Chen Shengqiang; Jope Richard S; Bauchwitz Robert P
Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.
Neuropharmacology 2009;56(2):463-72.
2009: Polter Abigail; Yang Sufen; Zmijewska Anna A; van Groen Thomas; Paik Ji-Hye; Depinho Ronald A; Peng Stanford L; Jope Richard S; Li Xiaohua
Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation.
Biological psychiatry 2009;65(2):150-9.
2009: Beurel Eléonore; Jope Richard S
Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain.
Journal of neuroinflammation 2009;6():9.
2009: Eom Tae-Yeon; Jope Richard S
GSK3 beta N-terminus binding to p53 promotes its acetylation.
Molecular cancer 2009;8():14.
2008: Sun M; Song L; Li Y; Zhou T; Jope R S
Identification of an antiapoptotic protein complex at death receptors.
Cell death and differentiation 2008;15(12):1887-900.
2008: Beurel Eléonore; Jope Richard S
Differential regulation of STAT family members by glycogen synthase kinase-3.
The Journal of biological chemistry 2008;283(32):21934-44.
2008: De Sarno Patrizia; Axtell Robert C; Raman Chander; Roth Kevin A; Alessi Dario R; Jope Richard S
Lithium prevents and ameliorates experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):338-45.
2008: Meares Gordon P; Zmijewska Anna A; Jope Richard S
HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation.
Cellular signalling 2008;20(2):347-58.
2007: Mookherjee Paramita; Quintanilla Rodrigo; Roh Myoung-Sun; Zmijewska Anna A; Jope Richard S; Johnson Gail V W
Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death.
Journal of cellular biochemistry 2007;102(1):196-210.
2007: Eom Tae-Yeon; Roth Kevin A; Jope Richard S
Neural precursor cells are protected from apoptosis induced by trophic factor withdrawal or genotoxic stress by inhibitors of glycogen synthase kinase 3.
The Journal of biological chemistry 2007;282(31):22856-64.
2007: Meares Gordon P; Jope Richard S
Resolution of the nuclear localization mechanism of glycogen synthase kinase-3: functional effects in apoptosis.
The Journal of biological chemistry 2007;282(23):16989-7001.
2007: Jope Richard S; Yuskaitis Christopher J; Beurel Eléonore
Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics.
Neurochemical research 2007;32(4-5):577-95.
2007: Li Xiaohua; Friedman Ari B; Zhu Wawa; Wang Li; Boswell Sherer; May Roberta S; Davis Lori L; Jope Richard S
Lithium regulates glycogen synthase kinase-3beta in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorder.
Biological psychiatry 2007;61(2):216-22.
2006: Clodfelder-Miller Buffie J; Zmijewska Anna A; Johnson Gail V W; Jope Richard S
Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency.
Diabetes 2006;55(12):3320-5.
2006: Jope Richard S; Roh Myoung-Sun
Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions.
Current drug targets 2006;7(11):1421-34.
2006: Beurel Eléonore; Jope Richard S
The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways.
Progress in neurobiology 2006;79(4):173-89.
2006: Song Ling; Jope Richard S
Cellular stress increases RGS2 mRNA and decreases RGS4 mRNA levels in SH-SY5Y cells.
Neuroscience letters 2006;402(3):205-9.
2006: King Taj D; Song Ling; Jope Richard S
AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.
Biochemical pharmacology 2006;71(11):1637-47.
2006: De Sarno Patrizia; Bijur Gautam N; Zmijewska Anna A; Li Xiaohua; Jope Richard S
In vivo regulation of GSK3 phosphorylation by cholinergic and NMDA receptors.
Neurobiology of aging 2006;27(3):413-22.
2005: Clodfelder-Miller Buffie; De Sarno Patrizia; Zmijewska Anna A; Song Ling; Jope Richard S
Physiological and pathological changes in glucose regulate brain Akt and glycogen synthase kinase-3.
The Journal of biological chemistry 2005;280(48):39723-31.
2005: Martin Michael; Rehani Kunal; Jope Richard S; Michalek Suzanne M
Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.
Nature immunology 2005;6(8):777-84.
2005: King Taj D; Jope Richard S
Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress.
Neuroreport 2005;16(6):597-601.
2005: De Sarno Patrizia; Shestopal Svetlana A; Zmijewska Anna A; Jope Richard S
Anti-apoptotic effects of muscarinic receptor activation are mediated by Rho kinase.
Brain research 2005;1041(1):112-5.
2005: Roh Myoung-Sun; Eom Tae-Yeon; Zmijewska Anna A; De Sarno Patrizia; Roth Kevin A; Jope Richard S
Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine.
Biological psychiatry 2005;57(3):278-86.
2005: Li Xiaohua; Friedman Ari B; Roh Myoung-Sun; Jope Richard S
Anesthesia and post-mortem interval profoundly influence the regulatory serine phosphorylation of glycogen synthase kinase-3 in mouse brain.
Journal of neurochemistry 2005;92(3):701-4.
2004: Zmijewski Jaroslaw W; Jope Richard S
Nuclear accumulation of glycogen synthase kinase-3 during replicative senescence of human fibroblasts.
Aging cell 2004;3(5):309-17.
2004: Meares Gordon P; Zmijewska Anna A; Jope Richard S
Heat shock protein-90 dampens and directs signaling stimulated by insulin-like growth factor-1 and insulin.
FEBS letters 2004;574(1-3):181-6.
2004: Li Xiaohua; Zhu Wawa; Roh Myoung-Sun; Friedman Ari B; Rosborough Kelley; Jope Richard S
In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(8):1426-31.
2004: Song Ling; Zhou Tong; Jope Richard S
Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor.
BMC neuroscience 2004;5():20.
2004: Jope Richard S; Johnson Gail V W
The glamour and gloom of glycogen synthase kinase-3.
Trends in biochemical sciences 2004;29(2):95-102.
2003: Bijur Gautam N; Jope Richard S
Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation.
Journal of neurochemistry 2003;87(6):1427-35.
2003: Bijur Gautam N; Jope Richard S
Glycogen synthase kinase-3 beta is highly activated in nuclei and mitochondria.
Neuroreport 2003;14(18):2415-9.
2003: Watcharasit Piyajit; Bijur Gautam N; Song Ling; Zhu Jianhui; Chen Xinbin; Jope Richard S
Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53.
The Journal of biological chemistry 2003;278(49):48872-9.
2003: Jope Richard S
Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes.
Trends in pharmacological sciences 2003;24(9):441-3.
2003: Jope Richard S
Should tobacco ban rule out governments too?
Nature 2003;422(6934):802.
2003: De Sarno Patrizia; Shestopal Svetlana A; King Taj D; Zmijewska Anna; Song Ling; Jope Richard S
Muscarinic receptor activation protects cells from apoptotic effects of DNA damage, oxidative stress, and mitochondrial inhibition.
The Journal of biological chemistry 2003;278(13):11086-93.
2002: De Sarno Patrizia; Li Xiaohua; Jope Richard S
Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium.
Neuropharmacology 2002;43(7):1158-64.
2002: Song Ling; De Sarno Patrizia; Jope Richard S
Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation.
The Journal of biological chemistry 2002;277(47):44701-8.
2002: Mai Lian; Jope Richard S; Li Xiaohua
BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents.
Journal of neurochemistry 2002;82(1):75-83.
2002: Watcharasit Piyajit; Bijur Gautam N; Zmijewski Jaroslaw W; Song Ling; Zmijewska Anna; Chen Xinbin; Johnson Gail V W; Jope Richard S
Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):7951-5.
2002: Li Xiaohua; Bijur Gautam N; Jope Richard S
Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection.
Bipolar disorders 2002;4(2):137-44.
2002: Jope R S; Bijur G N
Mood stabilizers, glycogen synthase kinase-3beta and cell survival.
Molecular psychiatry 2002;7 Suppl 1():S35-45.
2001: Zmijewski J W; Song L; Harkins L; Cobbs C S; Jope R S
Second messengers regulate RGS2 expression which is targeted to the nucleus.
Biochimica et biophysica acta 2001;1541(3):201-11.
2001: King T D; Bijur G N; Jope R S
Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium.
Brain research 2001;919(1):106-14.
2001: Grimes C A; Jope R S
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.
Progress in neurobiology 2001;65(4):391-426.
2001: Bijur G N; Jope R S
Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta.
The Journal of biological chemistry 2001;276(40):37436-42.
2001: Grimes C A; Jope R S
CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium.
Journal of neurochemistry 2001;78(6):1219-32.
2001: Zmijewski J W; Song L; Harkins L; Cobbs C S; Jope R S
Oxidative stress and heat shock stimulate RGS2 expression in 1321N1 astrocytoma cells.
Archives of biochemistry and biophysics 2001;392(2):192-6.
2001: Watcharasit P; Tucholski J; Jope R S
Src family kinase involvement in muscarinic receptor-induced tyrosine phosphorylation in differentiated SH-SY5Y cells.
Neurochemical research 2001;26(7):809-16.
2001: De Sarno P; Lesort M; Bijur G N; Johnson G V; Jope R S
Cholinergic- and stress-induced signaling activities in cells overexpressing wild-type and mutant presenilin-1.
Brain research 2001;903(1-2):226-30.
2001: Song L; Zmijewski J W; Jope R S
RGS2: regulation of expression and nuclear localization.
Biochemical and biophysical research communications 2001;283(1):102-6.
2000: Bijur G N; Jope R S
Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity.
Journal of neurochemistry 2000;75(6):2401-8.
2000: Jope R S; Zhang L; Song L
Peroxynitrite modulates the activation of p38 and extracellular regulated kinases in PC12 cells.
Archives of biochemistry and biophysics 2000;376(2):365-70.
2000: Bijur G N; De Sarno P; Jope R S
Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium.
The Journal of biological chemistry 2000;275(11):7583-90.
2000: De Sarno P; Bijur G N; Lu R; Davis R E; Jope R S
Alterations in muscarinic receptor-coupled phosphoinositide hydrolysis and AP-1 activation in Alzheimer's disease cybrid cells.
Neurobiology of aging 2000;21(1):31-8.
1999: Jope R S
Cholinergic muscarinic receptor signaling by the phosphoinositide signal transduction system in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 1999;1(4-5):231-47.
1999: Zhang J; Tucholski J; Lesort M; Jope R S; Johnson G V
Novel bimodal effects of the G-protein tissue transglutaminase on adrenoreceptor signalling.
The Biochemical journal 1999;343 Pt 3():541-9.
1999: Pacheco M A; Jope R S
Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells.
Brain research. Molecular brain research 1999;72(2):138-46.
1999: Song L; De Sarno P; Jope R S
Muscarinic receptor stimulation increases regulators of G-protein signaling 2 mRNA levels through a protein kinase C-dependent mechanism.
The Journal of biological chemistry 1999;274(42):29689-93.
1999: Grimes C A; Jope R S
Cholinergic stimulation of early growth response-1 DNA binding activity requires protein kinase C and mitogen-activated protein kinase kinase activation and is inhibited by sodium valproate in SH-SY5Y cells.
Journal of neurochemistry 1999;73(4):1384-92.
1999: Bijur G N; Davis R E; Jope R S
Rapid activation of heat shock factor-1 DNA binding by H2O2 and modulation by glutathione in human neuroblastoma and Alzheimer's disease cybrid cells.
Brain research. Molecular brain research 1999;71(1):69-77.
1999: Zhang L; Jope R S
Oxidative stress differentially modulates phosphorylation of ERK, p38 and CREB induced by NGF or EGF in PC12 cells.
Neurobiology of aging 1999;20(3):271-8.
1999: Lu R; Song L; Jope R S
Lithium attenuates p53 levels in human neuroblastoma SH-SY5Y cells.
Neuroreport 1999;10(5):1123-5.
1999: Jope R S
Anti-bipolar therapy: mechanism of action of lithium.
Molecular psychiatry 1999;4(2):117-28.
1999: Jope R S; Song L; Grimes C A; Zhang L
Oxidative stress oppositely modulates protein tyrosine phosphorylation stimulated by muscarinic G protein-coupled and epidermal growth factor receptors.
Journal of neuroscience research 1999;55(3):329-40.
1999: Zhang L; Jope R S
Muscarinic M3 and epidermal growth factor receptors activate mutually inhibitory signaling cascades in human neuroblastoma SH-SY5Y cells.
Biochemical and biophysical research communications 1999;255(3):774-7.
1999: Lesort M; Jope R S; Johnson G V
Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase.
Journal of neurochemistry 1999;72(2):576-84.
1999: Jope R S
A bimodal model of the mechanism of action of lithium.
Molecular psychiatry 1999;4(1):21-5.
1999: Zhou T; Song L; Yang P; Wang Z; Lui D; Jope R S
Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases.
Nature medicine 1999;5(1):42-8.
1999: Lesort M; Greendorfer A; Stockmeier C; Johnson G V; Jope R S
Glycogen synthase kinase-3beta, beta-catenin, and tau in postmortem bipolar brain.
Journal of neural transmission (Vienna, Austria : 1996) 1999;106(11-12):1217-22.
1998: De Sarno P; Jope R S
Phosphoinositide hydrolysis activated by muscarinic or glutamatergic, but not adrenergic, receptors is impaired in ApoE-deficient mice and by hydrogen peroxide and peroxynitrite.
Experimental neurology 1998;152(1):123-8.
1998: Xie H; Litersky J M; Hartigan J A; Jope R S; Johnson G V
The interrelationship between selective tau phosphorylation and microtubule association.
Brain research 1998;798(1-2):173-83.
1998: Li X; De Sarno P; Song L; Beckman J S; Jope R S
Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signalling in human neuroblastoma SH-SY5Y cells: attenuated effects in human 1321N1 astrocytoma cells.
The Biochemical journal 1998;331 ( Pt 2)():599-606.
1998: Jope R S; Song L; Grimes C A; Pacheco M A; Dilley G E; Li X; Meltzer H Y; Overholser J C; Stockmeier C A
Selective increases in phosphoinositide signaling activity and G protein levels in postmortem brain from subjects with schizophrenia or alcohol dependence.
Journal of neurochemistry 1998;70(2):763-71.
1998: Li X; Song L; Jope R S
Glutathione depletion exacerbates impairment by oxidative stress of phosphoinositide hydrolysis, AP-1, and NF-kappaB activation by cholinergic stimulation.
Brain research. Molecular brain research 1998;53(1-2):196-205.
1997: Ordway J M; Tallaksen-Greene S; Gutekunst C A; Bernstein E M; Cearley J A; Wiener H W; Dure L S; Lindsey R; Hersch S M; Jope R S; Albin R L; Detloff P J
Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.
Cell 1997;91(6):753-63.
1997: Jope R S; Song L
AP-1 and NF-kappaB stimulated by carbachol in human neuroblastoma SH-SY5Y cells are differentially sensitive to inhibition by lithium.
Brain research. Molecular brain research 1997;50(1-2):171-80.
1997: Pacheco M A; Jope R S
Comparison of [3H]phosphatidylinositol and [3H]phosphatidylinositol 4,5-bisphosphate hydrolysis in postmortem human brain membranes and characterization of stimulation by dopamine D1 receptors.
Journal of neurochemistry 1997;69(2):639-44.
1997: Unlap M T; Jope R S
Lithium attenuates nerve growth factor-induced activation of AP-1 DNA binding activity in PC12 cells.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(1):12-7.
1997: Li X; Jope R S
Glucocorticoids modulate G-protein alpha-subunit levels in PC12 cells.
Brain research 1997;759(2):213-20.
1997: Unlap M T; Jope R S
Dexamethasone attenuates NF-kappa B DNA binding activity without inducing I kappa B levels in rat brain in vivo.
Brain research. Molecular brain research 1997;45(1):83-9.
1997: Jope R S; Song L; Powers R E
Cholinergic activation of phosphoinositide signaling is impaired in Alzheimer's disease brain.
Neurobiology of aging 1997;18(1):111-20.
1996: Pacheco M A; Jope R S
Phosphoinositide signaling in human brain.
Progress in neurobiology 1996;50(2-3):255-73.
1996: Li X; Song L; Jope R S
Cholinergic stimulation of AP-1 and NF kappa B transcription factors is differentially sensitive to oxidative stress in SH-SY5Y neuroblastoma: relationship to phosphoinositide hydrolysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(19):5914-22.
1996: Pacheco M A; Stockmeier C; Meltzer H Y; Overholser J C; Dilley G E; Jope R S
Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain.
Brain research 1996;723(1-2):37-45.
1996: Jope R S; Song L; Li P P; Young L T; Kish S J; Pacheco M A; Warsh J J
The phosphoinositide signal transduction system is impaired in bipolar affective disorder brain.
Journal of neurochemistry 1996;66(6):2402-9.
1996: Li X; Greenwood A F; Powers R; Jope R S
Effects of postmortem interval, age, and Alzheimer's disease on G-proteins in human brain.
Neurobiology of aging 1996;17(1):115-22.
1995: Williams M B; Jope R S
Circadian variation in rat brain AP-1 DNA binding activity after cholinergic stimulation: modulation by lithium.
Psychopharmacology 1995;122(4):363-8.
1995: Li X; Jope R S
Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells.
Journal of neurochemistry 1995;65(6):2500-8.
1995: Greenwood A F; Powers R E; Jope R S
Phosphoinositide hydrolysis, G alpha q, phospholipase C, and protein kinase C in post mortem human brain: effects of post mortem interval, subject age, and Alzheimer's disease.
Neuroscience 1995;69(1):125-38.
1995: Unlap T; Jope R S
Inhibition of NFkB DNA binding activity by glucocorticoids in rat brain.
Neuroscience letters 1995;198(1):41-4.
1995: Williams M B; Jope R S
Modulation by inositol of cholinergic- and serotonergic-induced seizures in lithium-treated rats.
Brain research 1995;685(1-2):169-78.
1995: Su X; Zhou T; Wang Z; Yang P; Jope R S; Mountz J D
Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis.
Immunity 1995;2(4):353-62.
1995: Li X; Mumby S M; Greenwood A; Jope R S
Pertussis toxin-sensitive G protein alpha-subunits: production of monoclonal antibodies and detection of differential increases on differentiation of PC12 and LA-N-5 cells.
Journal of neurochemistry 1995;64(3):1107-17.
1995: Unlap T; Jope R S
Diurnal variation in kainate-induced AP-1 activation in rat brain: influence of glucocorticoids.
Brain research. Molecular brain research 1995;28(2):193-200.
1994: Jope R S; Song L; Powers R
[3H]PtdIns hydrolysis in postmortem human brain membranes is mediated by the G-proteins Gq/11 and phospholipase C-beta.
The Biochemical journal 1994;304 ( Pt 2)():655-9.
1994: Williams M B; Jope R S
Protein synthesis inhibitors attenuate seizures induced in rats by lithium plus pilocarpine.
Experimental neurology 1994;129(1):169-73.
1994: Williams M B; Jope R S
Distinctive rat brain immediate early gene responses to seizures induced by lithium plus pilocarpine.
Brain research. Molecular brain research 1994;25(1-2):80-9.
1994: Bubien J K; Jope R S; Warnock D G
G-proteins modulate amiloride-sensitive sodium channels.
The Journal of biological chemistry 1994;269(27):17780-3.
1994: Unlap T; Jope R S
Dexamethasone attenuates kainate-induced AP-1 activation in rat brain.
Brain research. Molecular brain research 1994;24(1-4):275-82.
1994: Williams M B; Jope R S
Lithium potentiates phosphoinositide-linked 5-HT receptor stimulation in vivo.
Neuroreport 1994;5(9):1118-20.
1994: Jope R S; Song L; Li X; Powers R
Impaired phosphoinositide hydrolysis in Alzheimer's disease brain.
Neurobiology of aging 1994;15(2):221-6.
1994: Jope R S; Williams M B
Lithium and brain signal transduction systems.
Biochemical pharmacology 1994;47(3):429-41.
1994: Greenwood A F; Jope R S
Brain G-protein proteolysis by calpain: enhancement by lithium.
Brain research 1994;636(2):320-6.
1994: Jope R S; Song L; Powers R
Agonist-induced, GTP-dependent phosphoinositide hydrolysis in postmortem human brain membranes.
Journal of neurochemistry 1994;62(1):180-6.
1993: Song L; Baird M S; Jope R S
Hydrolysis of exogenous [3H]phosphatidylcholine by brain membranes and cytosol.
Neurochemical research 1993;18(12):1305-11.
1993: Kolasa K; Jope R S
Synergistic activation of phosphoinositide hydrolysis induced in brain slices by norepinephrine and the excitatory amino acid agonist, trans-ACPD.
Neuropharmacology 1993;32(1):21-8.
1993: Jope R S
Lithium selectively potentiates cholinergic activity in rat brain.
Progress in brain research 1993;98():317-22.
1992: Johnson G V; Jope R S
The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration.
Journal of neuroscience research 1992;33(4):505-12.
1992: Williams M B; Li X; Gu X; Jope R S
Modulation of endogenous ADP-ribosylation in rat brain.
Brain research 1992;592(1-2):49-56.
1992: Li X; Song L; Kolasa K; Jope R S
Adrenalectomy potentiates immediate early gene expression in rat brain.
Journal of neurochemistry 1992;58(6):2330-3.
1992: Song L; Jope R S
Chronic lithium treatment impairs phosphatidylinositol hydrolysis in membranes from rat brain regions.
Journal of neurochemistry 1992;58(6):2200-6.
1992: Kolasa K; Song L; Jope R S
Adrenalectomy increases phosphoinositide hydrolysis induced by norepinephrine or excitatory amino acids in rat hippocampal slices.
Brain research 1992;579(1):128-34.
1992: Jope R S; Song L; Kolasa K
Inositol trisphosphate, cyclic AMP, and cyclic GMP in rat brain regions after lithium and seizures.
Biological psychiatry 1992;31(5):505-14.
1992: Jope R S; Johnson G V
Neurotoxic effects of dietary aluminium.
Ciba Foundation symposium 1992;169():254-62; discussion 262-7.
1992: Johnson G V; Watson A L; Lartius R; Uemura E; Jope R S
Dietary aluminum selectively decreases MAP-2 in brains of developing and adult rats.
Neurotoxicology 1992;13(2):463-74.
1992: Jope R S; Kolasa K; Song L; Ormandy G C
Seizures selectively impair agonist-stimulated phosphoinositide hydrolysis without affecting protein kinase C activity in rat brain.
Neurotoxicology 1992;13(2):389-400.
1992: Kolasa K; Jope R S; Baird M S; Johnson G V
Alterations of choline acetyltransferase, phosphoinositide hydrolysis, and cytoskeletal proteins in rat brain in response to colchicine administration.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1992;89(3):496-500.
1991: Jope R S; Gu X
Seizures increase acetylcholine and choline concentrations in rat brain regions.
Neurochemical research 1991;16(11):1219-26.
1991: Jope R S; Johnson G V; Baird M S
Seizure-induced protein tyrosine phosphorylation in rat brain regions.
Epilepsia 1991;32(6):755-60.
1991: Ormandy G C; Jope R S
Pertussis toxin potentiates seizures induced by pilocarpine, kainic acid and N-methyl-D-aspartate.
Brain research 1991;553(1):51-7.
1991: Johnson G V; Litersky J M; Jope R S
Degradation of microtubule-associated protein 2 and brain spectrin by calpain: a comparative study.
Journal of neurochemistry 1991;56(5):1630-8.
1991: Ormandy G C; Song L; Jope R S
Analysis of the convulsant-potentiating effects of lithium in rats.
Experimental neurology 1991;111(3):356-61.
1991: Casebolt T L; Jope R S
Effects of chronic lithium treatment on protein kinase C and cyclic AMP-dependent protein phosphorylation.
Biological psychiatry 1991;29(3):233-43.
1990: Jope R S; Li X H; Ormandy G C; Song L; Williams M B
Reduction of Na+ enhances phosphoinositide hydrolysis and differentiates the stimulatory and inhibitory responses to quisqualate in rat brain slices.
Brain research 1990;536(1-2):251-6.
1990: Ormandy G C; Li X; Jope R S
Dibenzocycloalkenimine (MK-801) stimulates phosphoinositide hydrolysis in rat cerebral cortical slices).
Neuropharmacology 1990;29(8):779-82.
1990: Li X H; Song L; Jope R S
Modulation of phosphoinositide metabolism in rat brain slices by excitatory amino acids, arachidonic acid, and GABA.
Neurochemical research 1990;15(7):725-38.
1990: Johnson G V; Cogdill K W; Jope R S
Oral aluminum alters in vitro protein phosphorylation and kinase activities in rat brain.
Neurobiology of aging 1990;11(3):209-16.
1990: Miller J M; Jope R S; Ferraro T N; Hare T A
Brain amino acid concentrations in rats killed by decapitation and microwave irradiation.
Journal of neuroscience methods 1990;31(3):187-92.
1990: Harrell L E; Jope R S; Falgout J; Callaway R; Avery C; Spiers M; Leli D; Morere D; Halsey J H
Biological and neuropsychological characterization of physostigmine responders and nonresponders in Alzheimer's disease.
Journal of the American Geriatrics Society 1990;38(2):113-22.
1990: Ormandy G C; Jope R S
Inhibition of phosphoinositide hydrolysis by the novel neurotoxin beta-N-oxalyl-L-alpha, beta-diaminopropionic acid (L-BOAA).
Brain research 1990;510(1):53-7.
1990: Casebolt T L; Li X H; Jope R S
Alpha-1 adrenergic receptor binding and adrenergic-stimulated cyclic AMP production in rat cerebral cortex after chronic lithium treatment.
Journal of neural transmission. General section 1990;82(3):197-204.
1989: Ormandy G C; Jope R S; Snead O C
Anticonvulsant actions of MK-801 on the lithium-pilocarpine model of status epilepticus in rats.
Experimental neurology 1989;106(2):172-80.
1989: Jope R S; Miller J M; Ferraro T N; Hare T A
Chronic lithium treatment and status epilepticus induced by lithium and pilocarpine cause selective changes of amino acid concentrations in rat brain regions.
Neurochemical research 1989;14(9):829-34.
1989: Johnson G V; Jope R S; Binder L I
Proteolysis of tau by calpain.
Biochemical and biophysical research communications 1989;163(3):1505-11.
1989: Li X H; Jope R S
Inhibition of receptor-coupled phosphoinositide hydrolysis by sulfur-containing amino acids in rat brain slices.
Biochemical pharmacology 1989;38(17):2781-7.
1989: Connor D J; Harrell L E; Jope R S
Reversal of an aluminum-induced behavioral deficit by administration of deferoxamine.
Behavioral neuroscience 1989;103(4):779-83.
1989: Simonato M; Jope R S; Bianchi C; Beani L
Lack of excitatory amino acid-induced effects on calcium fluxes measured with 45Ca2+ in rat cerebral cortex synaptosomes.
Neurochemical research 1989;14(7):677-82.
1989: Johnson G V; Li X H; Jope R S
Aluminum increases agonist-stimulated cyclic AMP production in rat cerebral cortical slices.
Journal of neurochemistry 1989;53(1):258-63.
1989: Ormandy G C; Jope R S
Sodium nitroprusside and guanosine 3',5'-monophosphate (cyclic GMP) inhibit stimulated phosphoinositide hydrolysis in rat cerebral cortical slices.
Neuroscience letters 1989;100(1-3):287-91.
1989: Jope R S; Li X
Inhibition of inositol phospholipid synthesis and norepinephrine-stimulated hydrolysis in rat brain slices by excitatory amino acids.
Biochemical pharmacology 1989;38(4):589-96.
1989: Casebolt T L; Jope R S
Long-term lithium treatment selectively reduces receptor-coupled inositol phospholipid hydrolysis in rat brain.
Biological psychiatry 1989;25(3):329-40.
1988: Jope R S
Modulation of phosphoinositide hydrolysis by NaF and aluminum in rat cortical slices.
Journal of neurochemistry 1988;51(6):1731-6.
1988: Connor D J; Jope R S; Harrell L E
Chronic, oral aluminum administration to rats: cognition and cholinergic parameters.
Pharmacology, biochemistry, and behavior 1988;31(2):467-74.
1988: Johnson G V; Simonato M; Jope R S
Dose- and time-dependent hippocampal cholinergic lesions induced by ethylcholine mustard aziridinium ion: effects of nerve growth factor, GM1 ganglioside, and vitamin E.
Neurochemical research 1988;13(8):685-92.
1988: Johnson G V; Jope R S
Phosphorylation of rat brain cytoskeletal proteins is increased after orally administered aluminum.
Brain research 1988;456(1):95-103.
1988: Jope R S; Lally K M
Synaptosomal calcium influx is activated by sodium fluoride.
Biochemical and biophysical research communications 1988;151(2):774-80.
1988: Koenig M L; Jope R S
Effects of lithium on synaptosomal Ca2+ fluxes.
Psychopharmacology 1988;96(2):267-72.
1987: Morrisett R A; Jope R S; Snead O C
Status epilepticus is produced by administration of cholinergic agonists to lithium-treated rats: comparison with kainic acid.
Experimental neurology 1987;98(3):594-605.
1987: Koenig M L; Jope R S; Baker H J; Lally K M
Reduced Ca2+ flux in synaptosomes from cats with GM1 gangliosidosis.
Brain research 1987;424(1):169-76.
1987: Jope R S; Simonato M; Lally K
Acetylcholine content in rat brain is elevated by status epilepticus induced by lithium and pilocarpine.
Journal of neurochemistry 1987;49(3):944-51.
1987: Casebolt T L; Jope R S
Chronic lithium treatment reduces norepinephrine-stimulated inositol phospholipid hydrolysis in rat cortex.
European journal of pharmacology 1987;140(2):245-6.
1987: Jope R S; Casebolt T L; Johnson G V
Modulation of carbachol-stimulated inositol phospholipid hydrolysis in rat cerebral cortex.
Neurochemical research 1987;12(8):693-700.
1987: Morrisett R A; Jope R S; Snead O C
Effects of drugs on the initiation and maintenance of status epilepticus induced by administration of pilocarpine to lithium-pretreated rats.
Experimental neurology 1987;97(1):193-200.
1987: Koenig M L; Jope R S
Aluminum inhibits the fast phase of voltage-dependent calcium influx into synaptosomes.
Journal of neurochemistry 1987;49(1):316-20.
1987: Johnson G V; Jope R S
Aluminum alters cyclic AMP and cyclic GMP levels but not presynaptic cholinergic markers in rat brain in vivo.
Brain research 1987;403(1):1-6.
1986: Johnson G V; Jope R S
Aluminum increases cyclic AMP in rat cerebral cortex in vivo.
Life sciences 1986;39(14):1301-5.
1986: Jope R S; Morrisett R A
Neurochemical consequences of status epilepticus induced in rats by coadministration of lithium and pilocarpine.
Experimental neurology 1986;93(2):404-14.
1986: Johnson G V; Jope R S
Aluminum impairs glucose utilization and cholinergic activity in rat brain in vitro.
Toxicology 1986;40(1):93-102.
1986: Jope R S; Baker H J; Connor D J
Increased acetylcholine synthesis and release in brains of cats with GM1 gangliosidosis.
Journal of neurochemistry 1986;46(5):1567-72.
1986: Jope R S; Morrisett R A; Snead O C
Characterization of lithium potentiation of pilocarpine-induced status epilepticus in rats.
Experimental neurology 1986;91(3):471-80.
1986: Jope R S; Johnson G V
Quinacrine and 2-(4-phenylpiperidino)cyclohexanol (AH5183) inhibit acetylcholine release and synthesis in rat brain slices.
Molecular pharmacology 1986;29(1):45-51.
1986: Jope R S; Wright S M; Walter-Ryan W G; Alarcon R D
Effects of bipolar affective disorder and lithium administration on the cholinergic system in human blood.
Journal of psychiatric research 1986;20(1):9-18.
1985: Jope R S; Walter-Ryan W G; Alarcon R D; Lally K M
Cholinergic processes in blood samples from patients with major psychiatric disorders.
Biological psychiatry 1985;20(12):1258-66.
1985: Baker H J; Jope R S
Increased metabolism of acetylcholine in brain of cats with Gm1 gangliosidosis.
Brain research 1985;343(2):363-5.
1985: Jope R S; Tolbert L C; Wright S M; Walter-Ryan W
Biochemical RBC abnormalities in drug-free and lithium-treated manic patients.
The American journal of psychiatry 1985;142(3):356-8.
1984: Ringdahl B; Jope R S; Jenden D J
Inhibition of high affinity choline transport by stereoisomers of some 3-quinuclidinol derivatives.
Biochemical pharmacology 1984;33(17):2819-22.
1984: Jope R S; Jenden D J; Subramanian C S; Dhopeshwarker G A; Duncan J
Biochemical effects of phosphatidylcholine treatment in rats.
Biochemical pharmacology 1984;33(5):793-8.
1984: Jope R S; Wright S M; Jenden D J
Choline flux in human erythrocytes.
Psychopharmacology bulletin 1984;20(4):674-80.
1983: Kang-Lee Y A; McKee R W; Wright S M; Swendseid M E; Jenden D J; Jope R S
Metabolic effects of nicotinamide administration in rats.
The Journal of nutrition 1983;113(2):215-21.
1982: Bevan J A; Buga G M; Jope C A; Jope R S; Moritoki H
Further evidence for a muscarinic component to the neural vasodilator innervation of cerebral and cranial extracerebral arteries of the cat.
Circulation research 1982;51(4):421-9.
1982: Jope R S; Domino E F; Mathews B N; Sitaram N; Jenden D J; Ortez A
Free and bound choline blood levels after phosphatidylcholine.
Clinical pharmacology and therapeutics 1982;31(4):483-7.
1982: Jope R S
Effects of phosphatidylcholine administration to rats on choline in blood and choline and acetylcholine in brain.
The Journal of pharmacology and experimental therapeutics 1982;220(2):322-8.
1982: Diamond J M; Meier K; Gosenfeld L F; Jope R S; Jenden D J; Wright S M
Recovery of erythrocyte Li+/Na+ countertransport and choline transport from lithium therapy.
Journal of psychiatric research 1982;17(4):385-93.
1981: Jope R S
Acetylcholine turnover and compartmentation in rat brain synaptosomes.
Journal of neurochemistry 1981;36(5):1712-21.
1981: Jope R S; Jenden D J
Effects of acute ethanol treatment on cholinergic function in rats.
Substance and alcohol actions/misuse 1981;2(1):15-23.
1981: Russell R W; Pechnick R; Jope R S
Effects of lithium on behavioral reactivity: relation to increases in brain cholinergic activity.
Psychopharmacology 1981;73(2):120-5.
1980: Jope R S; Jenden D J; Ehrlich B E; Diamond J M; Gosenfeld L F
Erythrocyte choline concentrations are elevated in manic patients.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(10):6144-6.
1980: Jope R S; Jenden D J
The utilization of choline and acetyl coenzyme A for the synthesis of acetylcholine.
Journal of neurochemistry 1980;35(2):318-25.
1980: Fovall P; Dysken M W; Lazarus L W; Davis J M; Kahn R L; Jope R; Finkel S; Rattan P
Choline bitartrate treatment of Alzheimer-type dementias.
Communications in psychopharmacology 1980;4(2):141-5.
1980: Jenden D J; Jope R S; Fraser S L
A mechanism for the accumulation of choline in erythrocytes during treatment with lithium.
Communications in psychopharmacology 1980;4(5):339-44.
1979: Jope R S; Jenden D J
Dimethylaminoethanol (deanol) metabolism in rat brain and its effect on acetylcholine synthesis.
The Journal of pharmacology and experimental therapeutics 1979;211(3):472-9.
1979: Jope R S
High affinity choline transport and acetylCoA production in brain and their roles in the regulation of acetylcholine synthesis.
Brain research 1979;180(3):313-44.
1979: Russell R W; Carson V G; Jope R S; Booth R A; Macri J
Development of behavioral tolerance: a search for subcellular mechanisms.
Psychopharmacology 1979;66(2):155-8.
1979: Jope R
Effects of lithium treatment in vitro and in vivo on acetylcholine metabolism in rat brain.
Journal of neurochemistry 1979;33(2):487-95.
1979: Jope R S; Jenden D J
Choline and phospholipid metabolism and the synthesis of acetylcholine in rat brain.
Journal of neuroscience research 1979;4(1):69-82.
1978: Weiler M H; Jope R S; Jenden D J
Effect of pretreatment under various cationic conditions on acetylcholine content and choline transport in rat whole brain synaptosomes.
Journal of neurochemistry 1978;31(4):789-96.
1978: Jope R S; Jenden D J; Ehrlich B E; Diamond J M
Choline accumulates in erythrocytes during lithium therapy.
The New England journal of medicine 1978;299(15):833-4.
1978: Jope R S
Conditioned avoidance response and acetylcholine and choline levels in rat brain.
Journal of neurochemistry 1978;30(6):1625-6.
1978: Jope R S; Weiler M H; Jenden D J
Regulation of acetylcholine synthesis: control of choline transport and acetylation in synaptosomes.
Journal of neurochemistry 1978;30(5):949-54.
1977: Jope R S; Jenden D J
Synaptosomal transport and acetylation of choline.
Life sciences 1977;20(8):1389-92.
1976: Jenden D J; Jope R S; Weiler M H
Regulation of acetylcholine synthesis: does cytoplasmic acetylcholine control high affinity choline uptake?
Science (New York, N.Y.) 1976;194(4265):635-7.
1976: Jope R; Blass J P
The regulation of pyruvate dehydrogenase in brain in vivo.
Journal of neurochemistry 1976;26(4):709-14.
1975: Jope R; Blass J P
A comparison of the regulation of pyruvate dehydrogenase in mitochondria from rat brain and liver.
The Biochemical journal 1975;150(3):397-403.
1975: Gibson G E; Jope R; Blass J P
Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces.
The Biochemical journal 1975;148(1):17-23.
1975: Perlgut L E; Byers D L; Jope R S; Khamvinwathna V
Formation of triple-stranded bovine DNA in vitro.
Nature 1975;254(5495):86-7.

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