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Mary Ann Jordan

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Peter Hinow; Mary Ann Jordan; Manu Lopus; Vahid Rezania; Jack A Tuszyński
Modeling the effects of drug binding on the dynamic instability of microtubules.
Emin Oroudjev; Manu Lopus; Leslie Wilson; Charlene Audette; Carmela Provenzano; Hans Erickson; Yelena Kovtun; Ravi Chari; Mary Ann Jordan
Maytansinoid-antibody conjugates induce mitotic arrest by suppressing microtubule dynamic instability.
Manu Lopus; Emin Oroudjev; Leslie Wilson; Sharon Wilhelm; Wayne Widdison; Ravi Chari; Mary Ann Jordan
Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules.

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2011: Peter Hinow; Mary Ann Jordan; Manu Lopus; Vahid Rezania; Jack A Tuszyński
Modeling the effects of drug binding on the dynamic instability of microtubules.
Physical biology 2011;8(5):056004.
2010: Emin Oroudjev; Manu Lopus; Leslie Wilson; Charlene Audette; Carmela Provenzano; Hans Erickson; Yelena Kovtun; Ravi Chari; Mary Ann Jordan
Maytansinoid-antibody conjugates induce mitotic arrest by suppressing microtubule dynamic instability.
Molecular cancer therapeutics 2010;9(10):2700-13.
2010: Manu Lopus; Emin Oroudjev; Leslie Wilson; Sharon Wilhelm; Wayne Widdison; Ravi Chari; Mary Ann Jordan
Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules.
Molecular cancer therapeutics 2010;9(10):2689-99.
2010: Jennifer A Smith; Leslie Wilson; Olga Azarenko; X Zhu; Bryan M Lewis; Bruce A Littlefield; Mary Ann Jordan
Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability.
Biochemistry 2010;49(6):1331-7.
2010: Kathy Kamath; Emin Oroudjev; Mary Ann Jordan
Determination of microtubule dynamic instability in living cells.
Methods in cell biology 2010;97():1-14.
2010: Jennifer A Smith; Mary Ann Jordan
Determination of drug binding to microtubules in vitro.
Methods in cell biology 2010;95():289-99.
2010: Mythili Yenjerla; Nichole E LaPointe; Manu Lopus; Corey Cox; Mary Ann Jordan; Stuart C Feinstein; Leslie Wilson
The neuroprotective peptide NAP does not directly affect polymerization or dynamics of reconstituted neural microtubules.
Journal of Alzheimer's disease : JAD 2010;19(4):1377-86.
2010: Choong Jae Lee; Leslie Wilson; Mary Ann Jordan; Vy Nguyen; Jessica Tang; Gregory Smiyun
Hesperidin suppressed proliferations of both human breast cancer and androgen-dependent prostate cancer cells.
Phytotherapy research : PTR 2010;24 Suppl 1():S15-9.
2009: Mythili Yenjerla; Corey Cox; Leslie Wilson; Mary Ann Jordan
Carbendazim inhibits cancer cell proliferation by suppressing microtubule dynamics.
The Journal of pharmacology and experimental therapeutics 2009;328(2):390-8.
2008: Olga Azarenko; Tatiana Okouneva; Keith W Singletary; Mary Ann Jordan; Leslie Wilson
Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane.
Carcinogenesis 2008;29(12):2360-8.
2008: Tatiana Okouneva; Olga Azarenko; Leslie Wilson; Bruce A Littlefield; Mary Ann Jordan
Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase.
Molecular cancer therapeutics 2008;7(7):2003-11.
2008: Mary Ann Jordan; Susan B. Horwitz; Sharon Lobert; John J Correia
Exploring the mechanisms of action of the novel microtubule inhibitor vinflunine.
Seminars in oncology 2008;35(3 Suppl 3):S6-S12.
2007: Mary Ann Jordan; Kathy Kamath
How do microtubule-targeted drugs work? An overview.
Current cancer drug targets 2007;7(8):730-42.
2007: Hoyong Park; Sarah E Aiyar; Ping Fan; Jiping Wang; W Yue; Tatiana Okouneva; Corey Cox; Mary Ann Jordan; Lawrence Demers; Hyungjun Cho; Sanghee Kim; Robert X-D Song; Richard J Santen
Effects of tetramethoxystilbene on hormone-resistant breast cancer cells: biological and biochemical mechanisms of action.
Cancer research 2007;67(12):5717-26.
2007: Anasuya Ray; Tatiana Okouneva; Tapas Manna; Herbert P Miller; Steven Schmid; Larry Arthaud; Richard Luduena; Mary Ann Jordan; Leslie Wilson
Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (formerly ILX651) and its major metabolite tasidotin C-carboxylate.
Cancer research 2007;67(8):3767-76.
2006: Kathy Kamath; Tatiana Okouneva; Gary Larson; Dulal Panda; Leslie Wilson; Mary Ann Jordan
2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
Molecular cancer therapeutics 2006;5(9):2225-33.
2006: Janis M Bunker; Kathy Kamath; Leslie Wilson; Mary Ann Jordan; Stuart C Feinstein
FTDP-17 mutations compromise the ability of tau to regulate microtubule dynamics in cells.
The Journal of biological chemistry 2006;281(17):11856-63.
2005: Mary Ann Jordan; Kathy Kamath; Tapas Manna; Tatiana Okouneva; Herbert P Miller; Celia Davis; Bruce A Littlefield; Leslie Wilson
The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.
Molecular cancer therapeutics 2005;4(7):1086-95.
2005: Sasha Levy; Adria C Leboeuf; Michelle R Massie; Mary Ann Jordan; Leslie Wilson; Stuart C Feinstein
Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners. Implications for neurodegeneration.
The Journal of biological chemistry 2005;280(14):13520-8.
2005: Kathy Kamath; Leslie Wilson; Fernando Cabral; Mary Ann Jordan
BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability.
The Journal of biological chemistry 2005;280(13):12902-7.
2005: Eddy Pasquier; Stéphane Honore; Bertrand Pourroy; Mary Ann Jordan; Maxime Lehmann; Claudette Briand; Diane Braguer
Antiangiogenic concentrations of paclitaxel induce an increase in microtubule dynamics in endothelial cells but not in cancer cells.
Cancer research 2005;65(6):2433-40.
2004: Stéphane Honore; Kathy Kamath; Diane Braguer; Susan B. Horwitz; Leslie Wilson; Claudette Briand; Mary Ann Jordan
Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells.
Cancer research 2004;64(14):4957-64.
2004: Janis M Bunker; Leslie Wilson; Mary Ann Jordan; Stuart C Feinstein
Modulation of microtubule dynamics by tau in living cells: implications for development and neurodegeneration.
Molecular biology of the cell 2004;15(6):2720-8.
2004: Charles Dumontet; Jean-Pierre Jaffrezou; Etsuko Tsuchiya; George E Duran; Gang Chen; W Brent Derry; Leslie Wilson; Mary Ann Jordan; Kevin Gang Chen
Resistance to microtubule-targeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization.
Bulletin du cancer 2004;91(5):E81-112.
2003: Stéphane Honore; Kathy Kamath; Diane Braguer; Leslie Wilson; Claudette Briand; Mary Ann Jordan
Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation.
Molecular cancer therapeutics 2003;2(12):1303-11.
2003: Kathy Kamath; Mary Ann Jordan
Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest.
Cancer research 2003;63(18):6026-31.
2003: Jonathan Kelling; Kevin Sullivan; Leslie Wilson; Mary Ann Jordan
Suppression of centromere dynamics by Taxol in living osteosarcoma cells.
Cancer research 2003;63(11):2794-801.
2003: Tatiana Okouneva; Bridget T Hill; Leslie Wilson; Mary Ann Jordan
The effects of vinflunine, vinorelbine, and vinblastine on centromere dynamics.
Molecular cancer therapeutics 2003;2(5):427-36.
2002: Cori N Newton; Jennifer G DeLuca; Richard H Himes; Herbert P Miller; Mary Ann Jordan; Leslie Wilson
Intrinsically slow dynamic instability of HeLa cell microtubules in vitro.
The Journal of biological chemistry 2002;277(45):42456-62.
2002: Mary Ann Jordan
Mechanism of action of antitumor drugs that interact with microtubules and tubulin.
Current medicinal chemistry. Anti-cancer agents 2002;2(1):1-17.
2002: Mary Ann Jordan; Iwao Ojima; Francisco Rosas; Mariagrazia Distefano; Leslie Wilson; Giovanni Scambia; Ferlini Cristiano
Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis.
Chemistry & biology 2002;9(1):93-101.
2001: A Gonçalves; Diane Braguer; Kathy Kamath; L Martello; Claudette Briand; Susan B. Horwitz; Leslie Wilson; Mary Ann Jordan
Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11737-42.
2001: J G DeLuca; Cori N Newton; Richard H Himes; Mary Ann Jordan; Leslie Wilson
Purification and characterization of native conventional kinesin, HSET, and CENP-E from mitotic hela cells.
The Journal of biological chemistry 2001;276(30):28014-21.
2001: VK Ngan; K Bellman; Bridget T Hill; Leslie Wilson; Mary Ann Jordan
Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine.
Molecular pharmacology 2001;60(1):225-32.
2000: Dulal Panda; V Ananthnarayan; G Larson; C Shih; Mary Ann Jordan; Leslie Wilson
Interaction of the antitumor compound cryptophycin-52 with tubulin.
Biochemistry 2000;39(46):14121-7.
2000: Nicolas Andre; Diane Braguer; Gaël Brasseur; A Gonçalves; Danielle Lemesle-Meunier; S Guise; Mary Ann Jordan; Claudette Briand
Paclitaxel induces release of cytochrome c from mitochondria isolated from human neuroblastoma cells'.
Cancer research 2000;60(19):5349-53.
2000: VK Ngan; K Bellman; Dulal Panda; Bridget T Hill; Mary Ann Jordan; Leslie Wilson
Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules.
Cancer research 2000;60(18):5045-51.
1999: Leslie Wilson; Dulal Panda; Mary Ann Jordan
Modulation of microtubule dynamics by drugs: a paradigm for the actions of cellular regulators.
Cell structure and function 1999;24(5):329-35.
1999: Mary Ann Jordan; Leslie Wilson
The use and action of drugs in analyzing mitosis.
Methods in cell biology 1999;61():267-95.
1998: Mary Ann Jordan; D Walker; M de Arruda; T Barlozzari; Dulal Panda
Suppression of microtubule dynamics by binding of cemadotin to tubulin: possible mechanism for its antitumor action.
Biochemistry 1998;37(50):17571-8.
1998: D Panda; K DeLuca; D Williams; Mary Ann Jordan; L Wilson
Antiproliferative mechanism of action of cryptophycin-52: kinetic stabilization of microtubule dynamics by high-affinity binding to microtubule ends.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9313-8.
1998: W Brent Derry; Leslie Wilson; Mary Ann Jordan
Low potency of taxol at microtubule minus ends: implications for its antimitotic and therapeutic mechanism.
Cancer research 1998;58(6):1177-84.
1998: Mary Ann Jordan; Leslie Wilson
Use of drugs to study role of microtubule assembly dynamics in living cells.
Methods in enzymology 1998;298():252-76.
1997: Dulal Panda; Richard H Himes; R E Moore; Leslie Wilson; Mary Ann Jordan
Mechanism of action of the unusually potent microtubule inhibitor cryptophycin 1.
Biochemistry 1997;36(42):12948-53.
1997: D L Wood; D Panda; T R Wiernicki; L Wilson; Mary Ann Jordan; J P Singh
Inhibition of mitosis and microtubule function through direct tubulin binding by a novel antiproliferative naphthopyran LY290181.
Molecular pharmacology 1997;52(3):437-44.
1997: W Brent Derry; Leslie Wilson; I A Khan; Richard Luduena; Mary Ann Jordan
Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes.
Biochemistry 1997;36(12):3554-62.
1996: Dulal Panda; Mary Ann Jordan; K C Chu; Leslie Wilson
Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends.
The Journal of biological chemistry 1996;271(47):29807-12.
1996: Mary Ann Jordan; K Wendell; S Gardiner; W Brent Derry; H Copp; Leslie Wilson
Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.
Cancer research 1996;56(4):816-25.
1996: D A Thrower; Mary Ann Jordan; Leslie Wilson
Modulation of CENP-E organization at kinetochores by spindle microtubule attachment.
Cell motility and the cytoskeleton 1996;35(2):121-33.
1995: Leslie Wilson; Mary Ann Jordan
Microtubule dynamics: taking aim at a moving target.
Chemistry & biology 1995;2(9):569-73.
1995: R Dhamodharan; Mary Ann Jordan; D Thrower; Leslie Wilson; Patricia Wadsworth
Vinblastine suppresses dynamics of individual microtubules in living interphase cells.
Molecular biology of the cell 1995;6(9):1215-29.
1995: Dulal Panda; J E Daijo; Mary Ann Jordan; Leslie Wilson
Kinetic stabilization of microtubule dynamics at steady state in vitro by substoichiometric concentrations of tubulin-colchicine complex.
Biochemistry 1995;34(31):9921-9.
1995: D A Thrower; Mary Ann Jordan; B T Schaar; Tim J Yen; Leslie Wilson
Mitotic HeLa cells contain a CENP-E-associated minus end-directed microtubule motor.
The EMBO journal 1995;14(5):918-26.
1995: W Brent Derry; Leslie Wilson; Mary Ann Jordan
Substoichiometric binding of taxol suppresses microtubule dynamics.
Biochemistry 1995;34(7):2203-11.
1995: Jean-Pierre Jaffrézou; C Dumontet; W Brent Derry; George E Durán; G Chen; E Tsuchiya; Leslie Wilson; Mary Ann Jordan; Kevin Gang Chen
Novel mechanism of resistance to paclitaxel (Taxol) in human K562 leukemia cells by combined selection with PSC 833.
Oncology research 1995;7(10-11):517-27.
1994: A Fellous; V Prasad; R Ohayon; Mary Ann Jordan; Richard Luduena
Removal of the projection domain of microtubule-associated protein 2 alters its interaction with tubulin.
Journal of protein chemistry 1994;13(4):381-91.
1993: Mary Ann Jordan; R J Toso; D Thrower; Leslie Wilson
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9552-6.
1993: R J Toso; Mary Ann Jordan; K W Farrell; B Matsumoto; Leslie Wilson
Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine.
Biochemistry 1993;32(5):1285-93.
1993: K L Wendell; Leslie Wilson; Mary Ann Jordan
Mitotic block in HeLa cells by vinblastine: ultrastructural changes in kinetochore-microtubule attachment and in centrosomes.
Journal of cell science 1993;104 ( Pt 2)():261-74.
1993: D Thrower; Mary Ann Jordan; Leslie Wilson
A quantitative solid-phase binding assay for tubulin.
Methods in cell biology 1993;37():129-45.
1992: V Prasad; Mary Ann Jordan; Richard Luduena
Temperature sensitivity of vinblastine-induced tubulin polymerization in the presence of microtubule-associated proteins.
Journal of protein chemistry 1992;11(5):509-15.
1992: Mary Ann Jordan; D Thrower; Leslie Wilson
Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis.
Journal of cell science 1992;102 ( Pt 3)():401-16.
1991: Mary Ann Jordan; D Thrower; Leslie Wilson
Mechanism of inhibition of cell proliferation by Vinca alkaloids.
Cancer research 1991;51(8):2212-22.
1991: D Thrower; Mary Ann Jordan; Leslie Wilson
Quantitation of cellular tubulin in microtubules and tubulin pools by a competitive ELISA.
Journal of immunological methods 1991;136(1):45-51.
1990: Mary Ann Jordan; Leslie Wilson
Kinetic analysis of tubulin exchange at microtubule ends at low vinblastine concentrations.
Biochemistry 1990;29(11):2730-9.
1987: A Banerjee; Mary Ann Jordan; M Little; Richard Luduena
The interaction of cystamine with bovine brain tubulin.
European journal of biochemistry / FEBS 1987;165(2):443-8.
1986: Richard Luduena; W H Anderson; V Prasad; Mary Ann Jordan; K C Ferrigni; M C Roach; P M Horowitz; Douglas B. Murphy; A Fellous
Interactions of vinblastine and maytansine with tubulin.
Annals of the New York Academy of Sciences 1986;466():718-32.
1985: A Fellous; Richard Luduena; V Prasad; Mary Ann Jordan; W Anderson; R Ohayon; P T Smith
Effects of Tau and MAP2 on the interaction of maytansine with tubulin: inhibitory effect of maytansine on vinblastine-induced aggregation of tubulin.
Cancer research 1985;45(10):5004-10.
1985: A Banerjee; Mary Ann Jordan; Richard Luduena
Interaction of reduced glutathione with bovine brain tubulin.
Biochemical and biophysical research communications 1985;128(2):506-12.
1985: Richard Luduena; M C Roach; Mary Ann Jordan; Douglas B. Murphy
Different reactivities of brain and erythrocyte tubulins toward a sulfhydryl group-directed reagent that inhibits microtubule assembly.
The Journal of biological chemistry 1985;260(2):1257-64.
1984: Richard Luduena; A Fellous; Linda McManus; Mary Ann Jordan; J Nunez
Contrasting roles of tau and microtubule-associated protein 2 in the vinblastine-induced aggregation of brain tubulin.
The Journal of biological chemistry 1984;259(20):12890-8.
1983: K W Farrell; R H Himes; Mary Ann Jordan; L Wilson
On the nonlinear relationship between the initial rates of dilution-induced microtubule disassembly and the initial free subunit concentration.
The Journal of biological chemistry 1983;258(23):14148-56.
1983: Mary Ann Jordan; K W Farrell
Differential radiolabeling of opposite microtubule ends: methodology, equilibrium exchange-flux analysis, and drug poisoning.
Analytical biochemistry 1983;130(1):41-53.
1982: K W Farrell; Mary Ann Jordan
A kinetic analysis of assembly-disassembly at opposite microtubule ends.
The Journal of biological chemistry 1982;257(6):3131-8.