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Lorne Babiuk
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91
van Drunen Littel-van den Hurk, Sylvia
58
Griebel, Philip
50
Tikoo, Suresh Kumar
37
Mutwiri, George
33
Baca-Estrada, Maria
27
Hecker, Rolf
23
Godson, Dale
21
Yoo, D
19
Babiuk, Shawn
16
Willson, Philip
16
Gerdts, Volker
16
Potter, Andrew
15
Foldvari, Marianna
14
Pontarollo, Reno
14
Liu, Qiang
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All Publications
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2009: Labiuk Shaunivan L; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Major tegument protein VP8 of bovine herpesvirus 1 is phosphorylated by viral US3 and cellular CK2 protein kinases.
The Journal of general virology 2009;90(Pt 12):2829-39.
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2009: Andrianov Alexander K; DeCollibus Daniel P; Gillis Helice A; Kha Henry H; Marin Alexander; Prausnitz Mark R; Babiuk Lorne A; Townsend Hugh; Mutwiri George
Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(45):18936-41.
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2009: Masic Aleksandar; Booth Jayaum S; Mutwiri George K; Babiuk Lorne A; Zhou Yan
Elastase-dependent live attenuated swine influenza A viruses are immunogenic and confer protection against swine influenza A virus infection in pigs.
Journal of virology 2009;83(19):10198-210.
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2009: Brownlie Robert; Zhu Jianzhong; Allan Brenda; Mutwiri George K; Babiuk Lorne A; Potter Andrew; Griebel Philip
Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides.
Molecular immunology 2009;46(15):3163-70.
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2009: Kovacs-Nolan J; Mapletoft J W; Lawman Z; Babiuk L A; van Drunen Littel-van den Hurk S
Formulation of bovine respiratory syncytial virus fusion protein with CpG oligodeoxynucleotide, cationic host defence peptide and polyphosphazene enhances humoral and cellular responses and induces a protective type 1 immune response in mice.
The Journal of general virology 2009;90(Pt 8):1892-905.
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2009: Kindrachuk Jason; Jenssen Håvard; Elliott Melissa; Townsend Rebecca; Nijnik Anastasia; Lee Song F; Gerdts Volker; Babiuk Lorne A; Halperin Scott A; Hancock Robert E W
A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity.
Vaccine 2009;27(34):4662-71.
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2009: Dar Arshud; Potter Andy; Tikoo Suresh; Gerdts Volker; Lai Ken; Babiuk Lorne A; Mutwiri George
CpG oligodeoxynucleotides activate innate immune response that suppresses infectious bronchitis virus replication in chicken embryos.
Avian diseases 2009;53(2):261-7.
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2009: Aich Palok; Babiuk Lorne A; Potter Andrew A; Griebel Philip
Biomarkers for prediction of bovine respiratory disease outcome.
Omics : a journal of integrative biology 2009;13(3):199-209.
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2009: Booth J S; Griebel P J; Babiuk L A; Mutwiri G K
A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses.
Mucosal immunology 2009;2(3):265-75.
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2009: Kovacs-Nolan J; Latimer L; Landi A; Jenssen H; Hancock R E W; Babiuk L A; van Drunen Littel-van den Hurk S
The novel adjuvant combination of CpG ODN, indolicidin and polyphosphazene induces potent antibody- and cell-mediated immune responses in mice.
Vaccine 2009;27(14):2055-64.
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2009: Kovacs-Nolan J; Mapletoft J W; Latimer L; Babiuk L A; Hurk S van Drunen Littel-van den
CpG oligonucleotide, host defense peptide and polyphosphazene act synergistically, inducing long-lasting, balanced immune responses in cattle.
Vaccine 2009;27(14):2048-54.
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2009: Mutwiri George; van Drunen Littel-van den Hurk Sylvia; Babiuk Lorne A
Approaches to enhancing immune responses stimulated by CpG oligodeoxynucleotides.
Advanced drug delivery reviews 2009;61(3):226-32.
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2009: Garlapati Srinivas; Facci Marina; Polewicz Monika; Strom Stacy; Babiuk Lorne A; Mutwiri George; Hancock Robert E W; Elliott Melissa R; Gerdts Volker
Strategies to link innate and adaptive immunity when designing vaccine adjuvants.
Veterinary immunology and immunopathology 2009;128(1-3):184-91.
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2009: Gaertner Frank H; Babiuk Lorne A; Mutwiri George; Armstrong Janna M; Griebel Philip J
Amended recombinant cells (ARCs) expressing bovine IFN-gamma: an economical and highly effective adjuvant system.
Vaccine 2009;27(9):1377-85.
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2009: Masic Aleksandar; Babiuk Lorne A; Zhou Yan
Reverse genetics-generated elastase-dependent swine influenza viruses are attenuated in pigs.
The Journal of general virology 2009;90(Pt 2):375-85.
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2009: Zhu Jianzhong; van Drunen Littel-van den Hurk Sylvia; Brownlie Robert; Babiuk Lorne A; Potter Andrew; Mutwiri George K
Multiple molecular regions confer intracellular localization of bovine Toll-like receptor 8.
Molecular immunology 2009;46(5):884-92.
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2009: Zhu Jianzhong; Brownlie Robert; Liu Qiang; Babiuk Lorne A; Potter Andrew; Mutwiri George K
Characterization of bovine Toll-like receptor 8: ligand specificity, signaling essential sites and dimerization.
Molecular immunology 2009;46(5):978-90.
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2009: Song Xin-Ming; Connor Wayne; Hokamp Karsten; Babiuk Lorne A; Potter Andrew A
The growth phase-dependent regulation of the pilus locus genes by two-component system TCS08 in Streptococcus pneumoniae.
Microbial pathogenesis 2009;46(1):28-35.
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2009: Song Xin-Ming; Connor Wayne; Hokamp Karsten; Babiuk Lorne A; Potter Andrew A
Transcriptome studies on Streptococcus pneumoniae, illustration of early response genes to THP-1 human macrophages.
Genomics 2009;93(1):72-82.
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2009: Jalal Shakiba; Arsenault Ryan; Potter Andrew A; Babiuk Lorne A; Griebel Philip J; Napper Scott
Genome to kinome: species-specific peptide arrays for kinome analysis.
Science signaling 2009;2(54):pl1.
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2008: Buza Joram; Benjamin Ponn; Zhu Jianzhung; Wilson Heather L; Lipford Grayson; Krieg Arthur M; Babiuk Lorne A; Mutwiri George K
CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands.
Veterinary immunology and immunopathology 2008;126(3-4):273-82.
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2008: Elahi Shokrollah; Thompson David R; Strom Stacy; O'Connor Brendan; Babiuk Lorne A; Gerdts Volker
Infection with Bordetella parapertussis but not Bordetella pertussis causes pertussis-like disease in older pigs.
The Journal of infectious diseases 2008;198(3):384-92.
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2008: Kindrachuk Jason; Potter Jean; Wilson Heather L; Griebel Philip; Babiuk Lorne A; Napper Scott
Activation and regulation of toll-like receptor 9: CpGs and beyond.
Mini reviews in medicinal chemistry 2008;8(6):590-600.
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2008: Zhu Jianzhong; Lai Ken; Brownile Robert; Babiuk Lorne A; Mutwiri George K
Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod.
Molecular immunology 2008;45(11):3238-43.
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2008: van Drunen Littel-van den Hurk S; Snider M; Thompson P; Latimer L; Babiuk L A
Strategies for induction of protective immunity to bovine herpesvirus-1 in newborn calves with maternal antibodies.
Vaccine 2008;26(25):3103-11.
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2008: Dar Arshud; Nichani Anil K; Benjamin Ponn; Lai Ken; Soita Henry; Krieg Arthur M; Potter Andrew; Babiuk Lorne A; Mutwiri George K
Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNalpha-producing cells and TLR9 mRNA expression.
Veterinary immunology and immunopathology 2008;123(3-4):324-36.
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2008: Yu H; Babiuk L A; van Drunen Littel-van den Hurk S
Strategies for loading dendritic cells with hepatitis C NS5a antigen and inducing protective immunity.
Journal of viral hepatitis 2008;15(6):459-70.
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2008: Mutwiri George; Benjamin Ponn; Soita Henry; Babiuk Lorne A
Co-administration of polyphosphazenes with CpG oligodeoxynucleotides strongly enhances immune responses in mice immunized with Hepatitis B virus surface antigen.
Vaccine 2008;26(22):2680-8.
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2008: Oem Jae-Ku; Jackel-Cram Candice; Li Yi-Ping; Zhou Yan; Zhong Jin; Shimano Hitoshi; Babiuk Lorne A; Liu Qiang
Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2.
The Journal of general virology 2008;89(Pt 5):1225-30.
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2008: Kaushik Radhey S; Begg Ashley A; Wilson Heather L; Aich Palok; Abrahamsen Mitchell S; Potter Andrew; Babiuk Lorne A; Griebel Philip
Establishment of fetal bovine intestinal epithelial cell cultures susceptible to bovine rotavirus infection.
Journal of virological methods 2008;148(1-2):182-96.
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2008: Liang R; van den Hurk J V; Landi A; Lawman Z; Deregt D; Townsend H; Babiuk L A; van Drunen Littel-van den Hurk S
DNA prime protein boost strategies protect cattle from bovine viral diarrhea virus type 2 challenge.
The Journal of general virology 2008;89(Pt 2):453-66.
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2008: Mapletoft John W; Oumouna Mustapha; Kovacs-Nolan Jennifer; Latimer Laura; Mutwiri George; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Intranasal immunization of mice with a formalin-inactivated bovine respiratory syncytial virus vaccine co-formulated with CpG oligodeoxynucleotides and polyphosphazenes results in enhanced protection.
The Journal of general virology 2008;89(Pt 1):250-60.
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2008: Song Xin-Ming; Connor Wayne; Hokamp Karsten; Babiuk Lorne A; Potter Andrew A
Streptococcus pneumoniae early response genes to human lung epithelial cells.
BMC research notes 2008;1():64.
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2008: Patel Bhavini A; Gomis Susantha; Dar Arshud; Willson Philip J; Babiuk Lorne A; Potter Andrew; Mutwiri George; Tikoo Suresh K
Oligodeoxynucleotides containing CpG motifs (CpG-ODN) predominantly induce Th1-type immune response in neonatal chicks.
Developmental and comparative immunology 2008;32(9):1041-9.
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2008: Oem J-K; Jackel-Cram C; Li Y-P; Kang H-N; Zhou Y; Babiuk L A; Liu Q
Hepatitis C virus non-structural protein-2 activates CXCL-8 transcription through NF-kappaB.
Archives of virology 2008;153(2):293-301.
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2007: Gerdts Volker; Littel-van den Hurk Sylvia van Drunen; Griebel Philip J; Babiuk Lorne A
Use of animal models in the development of human vaccines.
Future microbiology 2007;2():667-75.
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2007: Tsang Cemaine H; Mirakhur Kuldip K; Babiuk Lorne A; Griebel Philip J
Oral DNA immunization in the second trimester fetal lamb and secondary immune responses in the neonate.
Vaccine 2007;25(50):8469-79.
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2007: Shin Yeun-Kyung; Li Yang; Liu Qiang; Anderson Deborah H; Babiuk Lorne A; Zhou Yan
SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation.
Journal of virology 2007;81(23):12730-9.
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2007: Aich Palok; Wilson Heather L; Kaushik Radhey S; Potter Andy A; Babiuk Lorne A; Griebel Philip
Comparative analysis of innate immune responses following infection of newborn calves with bovine rotavirus and bovine coronavirus.
The Journal of general virology 2007;88(Pt 10):2749-61.
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2007: Zakhartchouk Alexander N; Viswanathan Sathiyanarayanan; Moshynskyy Igor; Petric Martin; Babiuk Lorne A
Optimization of a DNA vaccine against SARS.
DNA and cell biology 2007;26(10):721-6.
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2007: Landi Abdolamir; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
High transfection efficiency, gene expression, and viability of monocyte-derived human dendritic cells after nonviral gene transfer.
Journal of leukocyte biology 2007;82(4):849-60.
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2007: Oem Jae-Ku; Xiang Zhonghua; Zhou Yan; Babiuk Lorne A; Liu Qiang
Utilization of RNA polymerase I promoter and terminator sequences to develop a DNA transfection system for the study of hepatitis C virus internal ribosomal entry site-dependent translation.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2007;40(1):55-9.
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2007: Liang Rong; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Compatibility of plasmids encoding bovine viral diarrhea virus type 1 and type 2 E2 in a single DNA vaccine formulation.
Vaccine 2007;25(32):5994-6006.
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2007: Moshynskyy Igor; Viswanathan Sathiyanarayanan; Vasilenko Natalia; Lobanov Vladislav; Petric Martin; Babiuk Lorne A; Zakhartchouk Alexander N
Intracellular localization of the SARS coronavirus protein 9b: evidence of active export from the nucleus.
Virus research 2007;127(1):116-21.
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2007: Tsang Cemaine; Babiuk Shawn; van Drunen Littel-van den Hurk Sylvia; Babiuk Lorne A; Griebel Philip
A single DNA immunization in combination with electroporation prolongs the primary immune response and maintains immune memory for six months.
Vaccine 2007;25(30):5485-94.
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2007: Jackel-Cram Candice; Babiuk Lorne A; Liu Qiang
Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: genotype-3a core has a stronger effect than genotype-1b core.
Journal of hepatology 2007;46(6):999-1008.
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2007: Kindrachuk Jason; Potter Jean E; Brownlie Robert; Ficzycz Andrew D; Griebel Philip J; Mookherjee Neeloffer; Mutwiri George K; Babiuk Lorne A; Napper Scott
Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9.
The Journal of biological chemistry 2007;282(19):13944-53.
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2007: Babiuk Shawn; Tsang Cemaine; van Drunen Littel-van den Hurk Sylvia; Babiuk Lorne A; Griebel Philip J
A single HBsAg DNA vaccination in combination with electroporation elicits long-term antibody responses in sheep.
Bioelectrochemistry (Amsterdam, Netherlands) 2007;70(2):269-74.
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2007: Mutwiri G; Gerdts V; Lopez M; Babiuk L A
Innate immunity and new adjuvants.
Revue scientifique et technique (International Office of Epizootics) 2007;26(1):147-56.
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2007: Gomis Susantha; Babiuk Lorne; Allan Brenda; Willson Philip; Waters Edwin; Hecker Rolf; Potter Andrew
Protection of chickens against a lethal challenge of Escherichia coli by a vaccine containing CpG oligodeoxynucleotides as an adjuvant.
Avian diseases 2007;51(1):78-83.
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2007: Shin Yeun-Kyung; Liu Qiang; Tikoo Suresh K; Babiuk Lorne A; Zhou Yan
Effect of the phosphatidylinositol 3-kinase/Akt pathway on influenza A virus propagation.
The Journal of general virology 2007;88(Pt 3):942-50.
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2007: Yu Hong; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Immunity and protection by adoptive transfer of dendritic cells transfected with hepatitis C NS3/4A mRNA.
Vaccine 2007;25(10):1701-11.
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2007: Nichani Anil K; Dar M Arshud; Krieg Arthur M; Mirakhur Kuldip K; Kaushik Radhey S; Griebel Philip J; Manuja Anju; Townsend Hugh G G; Babiuk Lorne A; Mutwiri George K
Systemic innate immune responses following intrapulmonary delivery of CpG oligodeoxynucleotides in sheep.
Veterinary immunology and immunopathology 2007;115(3-4):357-68.
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2007: Shin Yeun-Kyung; Liu Qiang; Tikoo Suresh K; Babiuk Lorne A; Zhou Yan
Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K.
The Journal of general virology 2007;88(Pt 1):13-8.
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2007: Mutwiri George; Benjamin Ponn; Soita Henry; Townsend Hugh; Yost Richard; Roberts Bryan; Andrianov Alexander K; Babiuk Lorne A
Poly[di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP) is a potent enhancer of mixed Th1/Th2 immune responses in mice immunized with influenza virus antigens.
Vaccine 2007;25(7):1204-13.
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2007: Booth Jayaum S; Nichani Anil K; Benjamin Ponn; Dar Arshud; Krieg Arthur M; Babiuk Lorne A; Mutwiri George K
Innate immune responses induced by classes of CpG oligodeoxynucleotides in ovine lymph node and blood mononuclear cells.
Veterinary immunology and immunopathology 2007;115(1-2):24-34.
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2007: Zakhartchouk Alexander N; Sharon Chetna; Satkunarajah Malathy; Auperin Thierry; Viswanathan Sathiyanarayanan; Mutwiri George; Petric Martin; See Raymond H; Brunham Robert C; Finlay B Brett; Cameron Cheryl; Kelvin David J; Cochrane Alan; Rini James M; Babiuk Lorne A
Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: implications for a subunit vaccine.
Vaccine 2007;25(1):136-43.
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2007: Aich Palok; Jalal Shakiba; Czuba Carly; Schatte Gabrielle; Herzog Katie; Olson Douglas J H; Ross Andrew R S; Potter Andy A; Babiuk Lorne A; Griebel Philip
Comparative approaches to the investigation of responses to stress and viral infection in cattle.
Omics : a journal of integrative biology 2007;11(4):413-34.
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2007: Chang Zhijie; Babiuk Lorne A; Hu Jim
Therapeutic and prophylactic potential of small interfering RNAs against severe acute respiratory syndrome: progress to date.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2007;21(1):9-15.
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2007: Li X; Babiuk L A; Tikoo S K
Transcription mapping and characterization of proteins produced from early region 4 of porcine adenovirus type 3.
Archives of virology 2007;152(3):495-505.
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2006: Mookherjee Neeloffer; Wilson Heather L; Doria Silvana; Popowych Yurij; Falsafi Reza; Yu Jie Jessie; Li Yuexin; Veatch Sarah; Roche Fiona M; Brown Kelly L; Brinkman Fiona S L; Hokamp Karsten; Potter Andy; Babiuk Lorne A; Griebel Philip J; Hancock Robert E W
Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide.
Journal of leukocyte biology 2006;80(6):1563-74.
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2006: Li Yi-Ping; Kang Hye-Na; Babiuk Lorne-A; Liu Qiang
Elicitation of strong immune responses by a DNA vaccine expressing a secreted form of hepatitis C virus envelope protein E2 in murine and porcine animal models.
World journal of gastroenterology : WJG 2006;12(44):7126-35.
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2006: Lopez A M; Hecker R; Mutwiri G; van Drunen Littel-van den Hurk S; Babiuk L A; Townsend H G G
Formulation with CpG ODN enhances antibody responses to an equine influenza virus vaccine.
Veterinary immunology and immunopathology 2006;114(1-2):103-10.
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2006: Liang Rong; van den Hurk Jan V; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Priming with DNA encoding E2 and boosting with E2 protein formulated with CpG oligodeoxynucleotides induces strong immune responses and protection from Bovine viral diarrhea virus in cattle.
The Journal of general virology 2006;87(Pt 10):2971-82.
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2006: Mapletoft John W; Oumouna Mustapha; Townsend Hugh G; Gomis Susantha; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Formulation with CpG oligodeoxynucleotides increases cellular immunity and protection induced by vaccination of calves with formalin-inactivated bovine respiratory syncytial virus.
Virology 2006;353(2):316-23.
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2006: Whale Tyler A; Wilson Heather L; Tikoo Suresh K; Babiuk Lorne A; Griebel Philip J
Pivotal Advance: passively acquired membrane proteins alter the functional capacity of bovine polymorphonuclear cells.
Journal of leukocyte biology 2006;80(3):481-91.
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2006: Huang Y; Babiuk L A; van Drunen Littel-van den Hurk S
The cell-mediated immune response induced by plasmid encoding bovine herpesvirus 1 glycoprotein B is enhanced by plasmid encoding IL-12 when delivered intramuscularly or by gene gun, but not after intradermal injection.
Vaccine 2006;24(25):5349-59.
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2006: Whale Tyler A; Beskorwayne Terry K; Babiuk Lorne A; Griebel Philip J
Bovine polymorphonuclear cells passively acquire membrane lipids and integral membrane proteins from apoptotic and necrotic cells.
Journal of leukocyte biology 2006;79(6):1226-33.
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2006: Wilson Heather L; Dar Arshud; Napper Scott K; Marianela Lopez A; Babiuk Lorne A; Mutwiri George K
Immune mechanisms and therapeutic potential of CpG oligodeoxynucleotides.
International reviews of immunology 2006;25(3-4):183-213.
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2006: Elahi Shokrollah; Buchanan Rachelle M; Babiuk Lorne A; Gerdts Volker
Maternal immunity provides protection against pertussis in newborn piglets.
Infection and immunity 2006;74(5):2619-27.
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2006: Gerdts Volker; Mutwiri George K; Tikoo Suresh K; Babiuk Lorne A
Mucosal delivery of vaccines in domestic animals.
Veterinary research 2006;37(3):487-510.
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2006: Zheng C F; Brownlie R; Huang D Y; Babiuk L A; van Drunen Littel-van den Hurk S
Intercellular trafficking of the major tegument protein VP22 of bovine herpesvirus-1 and its application to improve a DNA vaccine.
Archives of virology 2006;151(5):985-93.
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2006: Zheng Chunfu; Juhls Christiane; Oswald Detlef; Sack Florian; Westfehling Ines; Wittig Burghardt; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Effect of different nuclear localization sequences on the immune responses induced by a MIDGE vector encoding bovine herpesvirus-1 glycoprotein D.
Vaccine 2006;24(21):4625-9.
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2006: Alcón Valeria L; Baca-Estrada Maria E; Potter Andrew; Babiuk Lorne A; Kumar Praveen; Foldvari Marianna
Biphasic lipid vesicles as a subcutaneous delivery system for protein antigens and CpG oligonucleotides.
Current drug delivery 2006;3(2):129-35.
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2006: Elahi Shokrollah; Buchanan Rachelle M; Attah-Poku Sam; Townsend Hugh G G; Babiuk Lorne A; Gerdts Volker
The host defense peptide beta-defensin 1 confers protection against Bordetella pertussis in newborn piglets.
Infection and immunity 2006;74(4):2338-52.
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2006: Higgs Rowan; Cormican Paul; Cahalane Sarah; Allan Brenda; Lloyd Andrew T; Meade Kieran; James Tharappel; Lynn David J; Babiuk Lorne A; O'farrelly Cliona
Induction of a novel chicken Toll-like receptor following Salmonella enterica serovar Typhimurium infection.
Infection and immunity 2006;74(3):1692-8.
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2006: See Raymond H; Zakhartchouk Alexander N; Petric Martin; Lawrence David J; Mok Catherine P Y; Hogan Robert J; Rowe Thomas; Zitzow Lois A; Karunakaran Karuna P; Hitt Mary M; Graham Frank L; Prevec Ludvik; Mahony James B; Sharon Chetna; Auperin Thierry C; Rini James M; Tingle Aubrey J; Scheifele David W; Skowronski Danuta M; Patrick David M; Voss Thomas G; Babiuk Lorne A; Gauldie Jack; Roper Rachel L; Brunham Robert C; Finlay B Brett
Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus.
The Journal of general virology 2006;87(Pt 3):641-50.
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2006: Sampathkumar Balamurugan; Napper Scott; Carrillo Catherine D; Willson Philip; Taboada Eduardo; Nash John H E; Potter Andrew A; Babiuk Lorne A; Allan Brenda J
Transcriptional and translational expression patterns associated with immobilized growth of Campylobacter jejuni.
Microbiology (Reading, England) 2006;152(Pt 2):567-77.
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2006: Yu Hong; Huang Hui; Xiang Jim; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Dendritic cells pulsed with hepatitis C virus NS3 protein induce immune responses and protection from infection with recombinant vaccinia virus expressing NS3.
The Journal of general virology 2006;87(Pt 1):1-10.
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2006: van Drunen Littel-van den Hurk Sylvia; Babiuk Shawn; Babiuk Lorne A
Needle-free delivery of veterinary DNA vaccines.
Methods in molecular medicine 2006;127():91-105.
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2006: Babiuk Shawn; van Drunen Littel-van den Hurk Sylvia; Babiuk Lorne A
Delivery of DNA vaccines using electroporation.
Methods in molecular medicine 2006;127():73-82.
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2006: Nichani Anil K; Mena Angelo; Kaushik Radhey S; Mutwiri George K; Townsend Hugh G G; Hecker Rolf; Krieg Arthur M; Babiuk Lorne A; Griebel Philip J
Stimulation of innate immune responses by CpG oligodeoxynucleotide in newborn lambs can reduce bovine herpesvirus-1 shedding.
Oligonucleotides 2006;16(1):58-67.
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2005: Liang Rong; van den Hurk Jan V; Zheng Chunfu; Yu Hong; Pontarollo Reno A; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Immunization with plasmid DNA encoding a truncated, secreted form of the bovine viral diarrhea virus E2 protein elicits strong humoral and cellular immune responses.
Vaccine 2005;23(45):5252-62.
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2005: Griebel Philip J; Brownlie Robert; Manuja Anju; Nichani Anil; Mookherjee Neeloffer; Popowych Yurij; Mutwiri George; Hecker Rolf; Babiuk Lorne A
Bovine toll-like receptor 9: a comparative analysis of molecular structure, function and expression.
Veterinary immunology and immunopathology 2005;108(1-2):11-6.
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2005: Gaertner Frank H; Babiuk Lorne A; Van Moorlehem Elaine A; Beskorwayne Terry K; Lee Stacey L; Shutter Robert W; Armstrong Janna M; Griebel Philip J
Amended recombinant cells (ARCs): an economical and surprisingly effective production and delivery vehicle for recombinant bovine IFN-gamma.
Journal of controlled release : official journal of the Controlled Release Society 2005;107(2):189-202.
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2005: Mutwiri George; Bowersock Terry L; Babiuk Lorne A
Microparticles for oral delivery of vaccines.
Expert opinion on drug delivery 2005;2(5):791-806.
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2005: Zheng Chunfu; Brownlie Robert; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Characterization of the nuclear localization and nuclear export signals of bovine herpesvirus 1 VP22.
Journal of virology 2005;79(18):11864-72.
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2005: Alcón V L; Baca-Estrada M; Vega-López M A; Willson P; Babiuk L A; Kumar P; Foldvari M
Intranasal immunization using biphasic lipid vesicles as delivery systems for OmlA bacterial protein antigen and CpG oligonucleotides adjuvant in a mouse model.
The Journal of pharmacy and pharmacology 2005;57(8):955-62.
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2005: Naas Turaya; Ghorbani Masoud; Alvarez-Maya Ikuri; Lapner Michael; Kothary Rashmi; De Repentigny Yves; Gomes Susantha; Babiuk Lorne; Giulivi Antonio; Soare Catalina; Azizi Ali; Diaz-Mitoma Francisco
Characterization of liver histopathology in a transgenic mouse model expressing genotype 1a hepatitis C virus core and envelope proteins 1 and 2.
The Journal of general virology 2005;86(Pt 8):2185-96.
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2005: Zakhartchouk Alexander N; Liu Qiang; Petric Martin; Babiuk Lorne A
Augmentation of immune responses to SARS coronavirus by a combination of DNA and whole killed virus vaccines.
Vaccine 2005;23(35):4385-91.
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2005: Vordermeier H Martin; Pontarollo Reno; Karvonen Brenda; Cockle Paul; Hecker Rolf; Singh Mahavir; Babiuk Lorne A; Hewinson R Glyn; van Drunen Littel-van Den Hurk Sylvia
Synthetic peptide vaccination in cattle: induction of strong cellular immune responses against peptides derived from the Mycobacterium bovis antigen Rv3019c.
Vaccine 2005;23(35):4375-84.
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2005: Wedlock D N; Skinner M A; de Lisle G W; Vordermeier H M; Hewinson R G; Hecker R; van Drunen Littel-van den Hurk S; Babiuk L A; Buddle B M
Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and CpG oligodeoxynucleotides induces protection against bovine tuberculosis.
Veterinary immunology and immunopathology 2005;106(1-2):53-63.
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2005: Elahi S; Brownlie R; Korzeniowski J; Buchanan R; O'Connor B; Peppler M S; Halperin S A; Lee S F; Babiuk L A; Gerdts V
Infection of newborn piglets with Bordetella pertussis: a new model for pertussis.
Infection and immunity 2005;73(6):3636-45.
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2005: Wedlock D Neil; Denis Michel; Skinner Margot A; Koach Jessica; de Lisle Geoffrey W; Vordermeier H Martin; Hewinson R Glyn; van Drunen Littel-van den Hurk Sylvia; Babiuk Lorne A; Hecker Rolf; Buddle Bryce M
Vaccination of cattle with a CpG oligodeoxynucleotide-formulated mycobacterial protein vaccine and Mycobacterium bovis BCG induces levels of protection against bovine tuberculosis superior to those induced by vaccination with BCG alone.
Infection and immunity 2005;73(6):3540-6.
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2005: Dar Arshud; Munir Shirin; Vishwanathan Satya; Manuja Anju; Griebel Philip; Tikoo Suresh; Townsend Hugh; Potter Andrew; Kapur Vivek; Babiuk Lorne A
Transcriptional analysis of avian embryonic tissues following infection with avian infectious bronchitis virus.
Virus research 2005;110(1-2):41-55.
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2005: Wilson Heather L; Aich Palok; Roche Fiona M; Jalal Shakiba; Hodgson Paul D; Brinkman Fiona S L; Potter Andy; Babiuk Lorne A; Griebel Philip J
Molecular analyses of disease pathogenesis: application of bovine microarrays.
Veterinary immunology and immunopathology 2005;105(3-4):277-87.
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2005: Li T; Zhang Y; Fu L; Yu C; Li X; Li Y; Zhang X; Rong Z; Wang Y; Ning H; Liang R; Chen W; Babiuk L A; Chang Z
siRNA targeting the leader sequence of SARS-CoV inhibits virus replication.
Gene therapy 2005;12(9):751-61.
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2005: Huang Y; Babiuk L A; van Drunen Littel-van den Hurk S
Immunization with a bovine herpesvirus 1 glycoprotein B DNA vaccine induces cytotoxic T-lymphocyte responses in mice and cattle.
The Journal of general virology 2005;86(Pt 4):887-98.
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2005: Oumouna M; Mapletoft J W; Karvonen B C; Babiuk L A; van Drunen Littel-van den Hurk S
Formulation with CpG oligodeoxynucleotides prevents induction of pulmonary immunopathology following priming with formalin-inactivated or commercial killed bovine respiratory syncytial virus vaccine.
Journal of virology 2005;79(4):2024-32.
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2005: Zheng Chunfu; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Bovine herpesvirus 1 VP22 enhances the efficacy of a DNA vaccine in cattle.
Journal of virology 2005;79(3):1948-53.
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2005: Zakhartchouk Alexander N; Viswanathan Sathiyanarayanan; Mahony James B; Gauldie Jack; Babiuk Lorne A
Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice.
The Journal of general virology 2005;86(Pt 1):211-5.
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2005: Alcon Valeria; Baca-Estrada Maria; Vega-Lopez Marco; Willson Philip; Babiuk Lorne A; Kumar Praveen; Hecker Rolf; Foldvari Marianna
Mucosal delivery of bacterial antigens and CpG oligonucleotides formulated in biphasic lipid vesicles in pigs.
The AAPS journal 2005;7(3):E566-71.
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2005: Skowronski Danuta M; Astell Caroline; Brunham Robert C; Low Donald E; Petric Martin; Roper Rachel L; Talbot Pierre J; Tam Theresa; Babiuk Lorne
Severe acute respiratory syndrome (SARS): a year in review.
Annual review of medicine 2005;56():357-81.
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2004: Gomis Susantha; Babiuk Lorne; Allan Brenda; Willson Philip; Waters Edwin; Ambrose Neil; Hecker Rolf; Potter Andrew
Protection of neonatal chicks against a lethal challenge of Escherichia coli using DNA containing cytosine-phosphodiester-guanine motifs.
Avian diseases 2004;48(4):813-22.
-
2004: Pérez Filgueira D M; Mozgovoj M; Wigdorovitz A; Dus Santos M J; Parreño V; Trono K; Fernandez F M; Carrillo C; Babiuk L A; Morris T J; Borca M V
Passive protection to bovine rotavirus (BRV) infection induced by a BRV VP8* produced in plants using a TMV-based vector.
Archives of virology 2004;149(12):2337-48.
-
2004: Babiuk Shawn; Mookherjee Neeloffer; Pontarollo Reno; Griebel Phillip; van Drunen Littel-van den Hurk Sylvia; Hecker Rolf; Babiuk Lorne
TLR9-/- and TLR9+/+ mice display similar immune responses to a DNA vaccine.
Immunology 2004;113(1):114-20.
-
2004: Li Xiaoxin; Babiuk Lorne A; Tikoo Suresh K
Analysis of early region 4 of porcine adenovirus type 3.
Virus research 2004;104(2):181-90.
-
2004: Wigdorovitz Andrés; Mozgovoj Marina; Santos María J Dus; Parreño Viviana; Gómez Cristina; Pérez-Filgueira Daniel M; Trono Karina G; Ríos Raúl D; Franzone Pascual M; Fernández Fernando; Carrillo Consuelo; Babiuk Lorne A; Escribano José M; Borca Manuel V
Protective lactogenic immunity conferred by an edible peptide vaccine to bovine rotavirus produced in transgenic plants.
The Journal of general virology 2004;85(Pt 7):1825-32.
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2004: Roche Fiona M; Hokamp Karsten; Acab Michael; Babiuk Lorne A; Hancock Robert E W; Brinkman Fiona S L
ProbeLynx: a tool for updating the association of microarray probes to genes.
Nucleic acids research 2004;32(Web Server issue):W471-4.
-
2004: Hokamp Karsten; Roche Fiona M; Acab Michael; Rousseau Marc-Etienne; Kuo Byron; Goode David; Aeschliman Dana; Bryan Jenny; Babiuk Lorne A; Hancock Robert E W; Brinkman Fiona S L
ArrayPipe: a flexible processing pipeline for microarray data.
Nucleic acids research 2004;32(Web Server issue):W457-9.
-
2004: Zheng Chunfu; Brownlie Robert; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Characterization of nuclear localization and export signals of the major tegument protein VP8 of bovine herpesvirus-1.
Virology 2004;324(2):327-39.
-
2004: van Drunen Littel-van den Hurk Sylvia; Babiuk Shawn L; Babiuk Lorne A
Strategies for improved formulation and delivery of DNA vaccines to veterinary target species.
Immunological reviews 2004;199():113-25.
-
2004: Yu Hong; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Priming with CpG-enriched plasmid and boosting with protein formulated with CpG oligodeoxynucleotides and Quil A induces strong cellular and humoral immune responses to hepatitis C virus NS3.
The Journal of general virology 2004;85(Pt 6):1533-43.
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2004: Manoj Sharmila; Griebel Philip J; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Modulation of immune responses to bovine herpesvirus-1 in cattle by immunization with a DNA vaccine encoding glycoprotein D as a fusion protein with bovine CD154.
Immunology 2004;112(2):328-38.
-
2004: Kulshreshtha Vikas; Babiuk Lorne A; Tikoo Suresh K
Role of bovine adenovirus-3 33K protein in viral replication.
Virology 2004;323(1):59-69.
-
2004: Mutwiri George K; Nichani Anil K; Babiuk Shawn; Babiuk Lorne A
Strategies for enhancing the immunostimulatory effects of CpG oligodeoxynucleotides.
Journal of controlled release : official journal of the Controlled Release Society 2004;97(1):1-17.
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2004: Babiuk Shawn; Baca-Estrada Maria E; Foldvari Marianna; Middleton Dorothy M; Rabussay Deitmar; Widera Georg; Babiuk Lorne A
Increased gene expression and inflammatory cell infiltration caused by electroporation are both important for improving the efficacy of DNA vaccines.
Journal of biotechnology 2004;110(1):1-10.
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2004: Carrillo Catherine D; Taboada Eduardo; Nash John H E; Lanthier Patricia; Kelly John; Lau Peter C; Verhulp Rachel; Mykytczuk Oksana; Sy Jonathan; Findlay Wendy A; Amoako Kingsley; Gomis Susantha; Willson Philip; Austin John W; Potter Andy; Babiuk Lorne; Allan Brenda; Szymanski Christine M
Genome-wide expression analyses of Campylobacter jejuni NCTC11168 reveals coordinate regulation of motility and virulence by flhA.
The Journal of biological chemistry 2004;279(19):20327-38.
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2004: Gerdts Volker; Tsang Cemaine; Griebel Philip J; Babiuk Lorne A
DNA vaccination in utero: a new approach to induce protective immunity in the newborn.
Vaccine 2004;22(13-14):1717-27.
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2004: Nichani A K; Mena A; Popowych Y; Dent D; Townsend H G G; Mutwiri G K; Hecker R; Babiuk L A; Griebel P J
In vivo immunostimulatory effects of CpG oligodeoxynucleotide in cattle and sheep.
Veterinary immunology and immunopathology 2004;98(1-2):17-29.
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2004: Zhang Yuanjiang; Li Tieshi; Fu Ling; Yu Changming; Li Yinghua; Xu Xialian; Wang Yinyin; Ning Hongxiu; Zhang Shuping; Chen Wei; Babiuk Lorne A; Chang Zhijie
Silencing SARS-CoV Spike protein expression in cultured cells by RNA interference.
FEBS letters 2004;560(1-3):141-6.
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2004: Babiuk Shawn; Baca-Estrada Maria E; Middleton Dorothy M; Hecker Rolf; Babiuk Lorne A; Foldvari Marianna
Biphasic lipid vesicles (Biphasix) enhance the adjuvanticity of CpG oligonucleotides following systemic and mucosal administration.
Current drug delivery 2004;1(1):9-15.
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2004: Nichani Anil K; Kaushik Radhey S; Mena Angelo; Popowych Yurij; Dent Donna; Townsend Hugh G G; Mutwiri George; Hecker Rolf; Babiuk Lorne A; Griebel Philip J
CpG oligodeoxynucleotide induction of antiviral effector molecules in sheep.
Cellular immunology 2004;227(1):24-37.
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2004: Babiuk Shawn; Skowronski Danuta M; De Serres Gaston; HayGlass Kent; Brunham Robert C; Babiuk Lorne
Aggregate content influences the Th1/Th2 immune response to influenza vaccine: evidence from a mouse model.
Journal of medical virology 2004;72(1):138-42.
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2004: Manoj Sharmila; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Approaches to enhance the efficacy of DNA vaccines.
Critical reviews in clinical laboratory sciences 2004;41(1):1-39.
-
2003: Babiuk Shawn; Baca-Estrada Maria E; Foldvari Marianna; Baizer Lawrence; Stout Richard; Storms Michael; Rabussay Dietmar; Widera Georg; Babiuk Lorne
Needle-free topical electroporation improves gene expression from plasmids administered in porcine skin.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(6):992-8.
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2003: Moshynskyy Igor; Jiang Min; Fontaine Michael C; Perez-Casal Jose; Babiuk Lorne A; Potter Andrew A
Characterization of a bovine lactoferrin binding protein of Streptococcus uberis.
Microbial pathogenesis 2003;35(5):203-15.
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2003: Mena Angelo; Nichani Anil K; Popowych Yurij; Godson Dale L; Dent Donna; Townsend Hugh G G; Mutwiri George K; Hecker Rolf; Babiuk Lorne A; Griebel Philip
Innate immune responses induced by CpG oligodeoxyribonucleotide stimulation of ovine blood mononuclear cells.
Immunology 2003;110(2):250-7.
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2003: Ioannou X P; Gomis S M; Hecker R; Babiuk L A; van Drunen Littel-van den Hurk S
Safety and efficacy of CpG-containing oligodeoxynucleotides as immunological adjuvants in rabbits.
Vaccine 2003;21(27-30):4368-72.
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2003: Manoj Sharmila; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Immunization with a dicistronic plasmid expressing a truncated form of bovine herpesvirus-1 glycoprotein D and the amino-terminal subunit of glycoprotein B results in reduced gB-specific immune responses.
Virology 2003;313(1):296-307.
-
2003: Babiuk L A; Gomis S; Hecker R
Molecular approaches to disease control.
Poultry science 2003;82(6):870-5.
-
2003: Alcón V L; Foldvari M; Snider M; Willson P; Gomis S; Hecker R; Babiuk L A; Baca-Estrada M E
Induction of protective immunity in pigs after immunisation with CpG oligodeoxynucleotides formulated in a lipid-based delivery system (Biphasix).
Vaccine 2003;21(17-18):1811-4.
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2003: Gomis Susantha; Babiuk Lorne; Godson Dale L; Allan Brenda; Thrush Tannis; Townsend Hugh; Willson Philip; Waters Edwin; Hecker Rolf; Potter Andrew
Protection of chickens against Escherichia coli infections by DNA containing CpG motifs.
Infection and immunity 2003;71(2):857-63.
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2003: Mutwiri G; Pontarollo R; Babiuk S; Griebel P; van Drunen Littel-van den Hurk S; Mena A; Tsang C; Alcon V; Nichani A; Ioannou X; Gomis S; Townsend H; Hecker R; Potter A; Babiuk L A
Biological activity of immunostimulatory CpG DNA motifs in domestic animals.
Veterinary immunology and immunopathology 2003;91(2):89-103.
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2003: Babiuk L A; Pontarollo R; Babiuk S; Loehr B; van Drunen Littel-van den Hurk S
Induction of immune responses by DNA vaccines in large animals.
Vaccine 2003;21(7-8):649-58.
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2003: Manoj Sharmila; Griebel Philip J; Babiuk Lorne A; van Drunen Littel-van den Hurk Sylvia
Targeting with bovine CD154 enhances humoral immune responses induced by a DNA vaccine in sheep.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):989-96.
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2003: Mena Angelo; Nichani Anil K; Popowych Yurij; Ioannou Xenia P; Godson Dale L; Mutwiri George K; Hecker Rolf; Babiuk Lorne A; Griebel Philip
Bovine and ovine blood mononuclear leukocytes differ markedly in innate immune responses induced by Class A and Class B CpG-oligodeoxynucleotide.
Oligonucleotides 2003;13(4):245-59.
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2003: Ioannou X P; Griebel P; Mena A; Gomis S M; Godson D L; Mutwiri G; Hecker R; Babiuk L A; van Drunen Littel-van den Hurk S
Safety of CpG oligodeoxynucleotides in veterinary species.
Antisense & nucleic acid drug development 2003;13(3):157-67.
-
2002: Stocki Stacy L; Babiuk Lorne A; Rawlyk Neil A; Potter Andrew A; Allan Brenda J
Identification of genomic differences between Escherichia coli strains pathogenic for poultry and E. coli K-12 MG1655 using suppression subtractive hybridization analysis.
Microbial pathogenesis 2002;33(6):289-98.
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2002: Kim B; Bowersock T; Griebel P; Kidane A; Babiuk L A; Sanchez M; Attah-Poku S; Kaushik R S; Mutwiri G K
Mucosal immune responses following oral immunization with rotavirus antigens encapsulated in alginate microspheres.
Journal of controlled release : official journal of the Controlled Release Society 2002;85(1-3):191-202.
-
2002: Pontarollo R A; Babiuk L A; Hecker R; Van Drunen Littel-Van Den Hurk S
Augmentation of cellular immune responses to bovine herpesvirus-1 glycoprotein D by vaccination with CpG-enhanced plasmid vectors.
The Journal of general virology 2002;83(Pt 12):2973-81.
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2002: Babiuk L A
Vaccination: a management tool in veterinary medicine.
Veterinary journal (London, England : 1997) 2002;164(3):188-201.
-
2002: Ioannou X P; Gomis S M; Karvonen B; Hecker R; Babiuk L A; van Drunen Littel-van den Hurk S
CpG-containing oligodeoxynucleotides, in combination with conventional adjuvants, enhance the magnitude and change the bias of the immune responses to a herpesvirus glycoprotein.
Vaccine 2002;21(1-2):127-37.
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2002: Liu Qiang; Wang Li; Willson Philip; O'Connor Brendan; Keenliside Julia; Chirino-Trejo Manuel; Meléndez Ronald; Babiuk Lorne
Seroprevalence of porcine circovirus type 2 in swine populations in Canada and Costa Rica.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 2002;66(4):225-31.
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2002: Baca-Estrada Maria E; Ewen Catherine; Mahony Donna; Babiuk Lorne A; Wilkie Darryl; Foldvari Marianna
The haemopoietic growth factor, Flt3L, alters the immune response induced by transcutaneous immunization.
Immunology 2002;107(1):69-76.
-
2002: Babiuk Shawn; Baca-Estrada Maria E; Foldvari Marianna; Storms Michael; Rabussay Deitmar; Widera Georg; Babiuk Lorne A
Electroporation improves the efficacy of DNA vaccines in large animals.
Vaccine 2002;20(27-28):3399-3408.
-
2002: Ioannou X P; Griebel P; Hecker R; Babiuk L A; van Drunen Littel-van den Hurk S
The immunogenicity and protective efficacy of bovine herpesvirus 1 glycoprotein D plus Emulsigen are increased by formulation with CpG oligodeoxynucleotides.
Journal of virology 2002;76(18):9002-10.
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2002: Mutwiri G; Bowersock T; Kidane A; Sanchez M; Gerdts V; Babiuk L A; Griebel P
Induction of mucosal immune responses following enteric immunization with antigen delivered in alginate microspheres.
Veterinary immunology and immunopathology 2002;87(3-4):269-76.
-
2002: Babiuk Lorne A
3rd World Congress on Vaccines and Immunisation. June 4-9 2002, Opatija Adriatic Riviera, Croatia.
Expert opinion on biological therapy 2002;2(6):665-9.
-
2002: Rankin R; Pontarollo R; Gomis S; Karvonen B; Willson P; Loehr B I; Godson D L; Babiuk L A; Hecker R; van Drunen Littel-van den Hurk S
CpG-containing oligodeoxynucleotides augment and switch the immune responses of cattle to bovine herpesvirus-1 glycoprotein D.
Vaccine 2002;20(23-24):3014-22.
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2002: Mena Angelo; Ioannou Xenia P; Van Kessel Andrew; Van Drunen Little-Van Den Hurk Sylvia; Popowych Yurij; Babiuk Lorne A; Godson Dale L
Th1/Th2 biasing effects of vaccination in cattle as determined by real-time PCR.
Journal of immunological methods 2002;263(1-2):11-21.
-
2002: Gerdts Volker; Snider Marlene; Brownlie Robert; Babiuk Lorne A; Griebel Philip J
Oral DNA vaccination in utero induces mucosal immunity and immune memory in the neonate.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1877-85.
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2002: Pontarollo R A; Rankin R; Babiuk L A; Godson D L; Griebel P J; Hecker R; Krieg A M; van Drunen Littel-van den Hurk S
Monocytes are required for optimum in vitro stimulation of bovine peripheral blood mononuclear cells by non-methylated CpG motifs.
Veterinary immunology and immunopathology 2002;84(1-2):43-59.
-
2002: Babiuk Lorne A; Babiuk Shawn L; Baca-Estrada Maria E
Novel vaccine strategies.
Advances in virus research 2002;58():29-80.
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2001: Uwiera R R; Gerdts V; Pontarollo R A; Babiuk L A; Middleton D M; Griebel P J
Plasmid DNA induces increased lymphocyte trafficking: a specific role for CpG motifs.
Cellular immunology 2001;214(2):155-64.
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2001: Loehr B I; Pontarollo R; Rankin R; Latimer L; Willson P; Babiuk L A; van Drunen Littel-van den Hurk S
Priming by DNA immunization augments T-cell responses induced by modified live bovine herpesvirus vaccine.
The Journal of general virology 2001;82(Pt 12):3035-43.
-
2001: Potter A A; Babiuk L A
New approaches for antigen discovery, production and delivery: vaccines for veterinary and human use.
Current drug targets. Infectious disorders 2001;1(3):249-62.
-
2001: Baxi M K; Robertson J; Babiuk L A; Tikoo S K
Mutational analysis of early region 4 of bovine adenovirus type 3.
Virology 2001;290(1):153-63.
-
2001: Suradhat S; Braun R P; Lewis P J; Babiuk L A; van Drunen Littel-van den Hurk S; Griebel P J; Baca-Estrada M E
Fusion of C3d molecule with bovine rotavirus VP7 or bovine herpesvirus type 1 glycoprotein D inhibits immune responses following DNA immunization.
Veterinary immunology and immunopathology 2001;83(1-2):79-92.
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2001: Rankin R; Pontarollo R; Ioannou X; Krieg A M; Hecker R; Babiuk L A; van Drunen Littel-van den Hurk S
CpG motif identification for veterinary and laboratory species demonstrates that sequence recognition is highly conserved.
Antisense & nucleic acid drug development 2001;11(5):333-40.
-
2001: Loehr B I; Rankin R; Pontarollo R; King T; Willson P; Babiuk L A; van Drunen Littel-van den Hurk S
Suppository-mediated DNA immunization induces mucosal immunity against bovine herpesvirus-1 in cattle.
Virology 2001;289(2):327-33.
-
2001: Gerdts V; Uwiera R R; Mutwiri G K; Wilson D J; Bowersock T; Kidane A; Babiuk L A; Griebel P J
Multiple intestinal 'loops' provide an in vivo model to analyse multiple mucosal immune responses.
Journal of immunological methods 2001;256(1-2):19-33.
-
2001: Zhou Y; Reddy P S; Babiuk L A; Tikoo S K
Bovine adenovirus type 3 E1B(small) protein is essential for growth in bovine fibroblast cells.
Virology 2001;288(2):264-74.
-
2001: Liu Q; Tikoo S K; Babiuk L A
Nuclear localization of the ORF2 protein encoded by porcine circovirus type 2.
Virology 2001;285(1):91-9.
-
2001: van Drunen Littel-van den Hurk S; Myers D; Doig P A; Karvonen B; Habermehl M; Babiuk L A; Jelinski M; Van Donkersgoed J; Schlesinger K; Rinehart C
Identification of a mutant bovine herpesvirus-1 (BHV-1) in post-arrival outbreaks of IBR in feedlot calves and protection with conventional vaccination.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 2001;65(2):81-8.
-
2001: van Drunen Littel-van den Hurk S; Loehr B I; Babiuk L A
Immunization of livestock with DNA vaccines: current studies and future prospects.
Vaccine 2001;19(17-19):2474-9.
-
2001: Uwiera R R; Rankin R; Adams G P; Pontarollo R; van Drunen Littel-van den Hurk S; Middleton D M; Babiuk L A; Griebel P J
Effects of intradermally administered plasmid deoxyribonucleic acid on ovine popliteal lymph node morphology.
The Anatomical record 2001;262(2):186-92.
-
2001: Liu Q; Willson P; Attoh-Poku S; Babiuk L A
Bacterial expression of an immunologically reactive PCV2 ORF2 fusion protein.
Protein expression and purification 2001;21(1):115-20.
-
2001: Zakhartchouk A N; Godson D L; Babiuk L A; Tikoo S K
121R protein from the E3 region of bovine adenovirus-3 inhibits cytolysis of mouse cells by human tumor necrosis factor.
Intervirology 2001;44(1):29-35.
-
2000: Baxi M K; Deregt D; Robertson J; Babiuk L A; Schlapp T; Tikoo S K
Recombinant bovine adenovirus type 3 expressing bovine viral diarrhea virus glycoprotein E2 induces an immune response in cotton rats.
Virology 2000;278(1):234-43.
-
2000: Tatlow D; Brownlie R; Babiuk L A; Griebel P
Differential display analysis of gene expression during the induction of mucosal immunity.
Immunogenetics 2000;52(1-2):73-80.
-
2000: Raggo C; Habermehl M; Babiuk L A; Griebel P
The in vivo effects of recombinant bovine herpesvirus-1 expressing bovine interferon-gamma.
The Journal of general virology 2000;81(Pt 11):2665-73.
-
2000: Reddy P S; Idamakanti N; Pyne C; Zakhartchouk A N; Godson D L; Papp Z; Baca-Estrada M E; Babiuk L A; Mutwiri G K; Tikoo S K
The immunogenicity and efficacy of replication-defective and replication-competent bovine adenovirus-3 expressing bovine herpesvirus-1 glycoprotein gD in cattle.
Veterinary immunology and immunopathology 2000;76(3-4):257-68.
-
2000: Reddy P S; Idamakanti N; Zakhartchouk L N; Babiuk L A; Mehtali M; Tikoo S K
Optimization of bovine coronavirus hemagglutinin-estrase glycoprotein expression in E3 deleted bovine adenovirus-3.
Virus research 2000;70(1-2):65-73.
-
2000: Babiuk L A; Tikoo S K
Adenoviruses as vectors for delivering vaccines to mucosal surfaces.
Journal of biotechnology 2000;83(1-2):105-13.
-
2000: Baca-Estrada M E; Foldvari M; Babiuk S L; Babiuk L A
Vaccine delivery: lipid-based delivery systems.
Journal of biotechnology 2000;83(1-2):91-104.
-
2000: Liu Q; Wang L; Willson P; Babiuk L A
Quantitative, competitive PCR analysis of porcine circovirus DNA in serum from pigs with postweaning multisystemic wasting syndrome.
Journal of clinical microbiology 2000;38(9):3474-7.
-
2000: van Drunen Littel-van den Hurk S; Gerdts V; Loehr B I; Pontarollo R; Rankin R; Uwiera R; Babiuk L A
Recent advances in the use of DNA vaccines for the treatment of diseases of farmed animals.
Advanced drug delivery reviews 2000;43(1):13-28.
-
2000: Babiuk L A; Babiuk S L; Loehr B I; van Drunnen Littel-van den Hur
Nucleic acid vaccines: research tool or commercial reality.
Veterinary immunology and immunopathology 2000;76(1-2):1-23.
-
2000: Gerdts V; Babiuk L A; van Drunen Littel-van den Hurk; Griebel P J
Fetal immunization by a DNA vaccine delivered into the oral cavity.
Nature medicine 2000;6(8):929-32.
-
2000: Loehr B I; Willson P; Babiuk L A; van Drunen Littel-van den Hurk
Gene gun-mediated DNA immunization primes development of mucosal immunity against bovine herpesvirus 1 in cattle.
Journal of virology 2000;74(13):6077-86.
-
2000: Babiuk S; Baca-Estrada M; Babiuk L A; Ewen C; Foldvari M
Cutaneous vaccination: the skin as an immunologically active tissue and the challenge of antigen delivery.
Journal of controlled release : official journal of the Controlled Release Society 2000;66(2-3):199-214.
-
2000: Baca-Estrada M E; Foldvari M M; Snider M M; Harding K K; Kournikakis B B; Babiuk L A; Griebel P P
Intranasal immunization with liposome-formulated Yersinia pestis vaccine enhances mucosal immune responses.
Vaccine 2000;18(21):2203-11.
-
2000: Baca-Estrada M E; Foldvari M; Ewen C; Badea I; Babiuk L A
Effects of IL-12 on immune responses induced by transcutaneous immunization with antigens formulated in a novel lipid-based biphasic delivery system.
Vaccine 2000;18(17):1847-54.
-
2000: Babiuk L A; van Drunen Littel-van den Hurk S; Loehr B I; Uwiera R
Veterinary applications of DNA vaccines.
Developments in biologicals 2000;104():73-81.
-
1999: Babiuk L A; van Drunen Littel-van den Hurk; Babiuk S L
Immunization of animals: from DNA to the dinner plate.
Veterinary immunology and immunopathology 1999;72(1-2):189-202.
-
1999: Braun R P; Babiuk L A; Loehr B I; van Drunen Littel-van den Hurk
Particle-mediated DNA immunization of cattle confers long-lasting immunity against bovine herpesvirus-1.
Virology 1999;265(1):46-56.
-
1999: Lewis P J; van Drunen Littel-van den Hurk; Babiuk L A
Altering the cellular location of an antigen expressed by a DNA-based vaccine modulates the immune response.
Journal of virology 1999;73(12):10214-23.
-
1999: Reddy P S; Idamakanti N; Babiuk L A; Mehtali M; Tikoo S K
Porcine adenovirus-3 as a helper-dependent expression vector.
The Journal of general virology 1999;80 ( Pt 11)():2909-16.
-
1999: Lewis P J; van Drunen Littel-Van Den Hurk; Babiuk L A
Induction of immune responses to bovine herpesvirus type 1 gD in passively immune mice after immunization with a DNA-based vaccine.
The Journal of general virology 1999;80 ( Pt 11)():2829-37.
-
1999: Reddy P S; Idamakanti N; Chen Y; Whale T; Babiuk L A; Mehtali M; Tikoo S K
Replication-defective bovine adenovirus type 3 as an expression vector.
Journal of virology 1999;73(11):9137-44.
-
1999: Baxi M K; Babiuk L A; Mehtali M; Tikoo S K
Transcription map and expression of bovine herpesvirus-1 glycoprotein D in early region 4 of bovine adenovirus-3.
Virology 1999;261(1):143-52.
-
1999: van Drunen Littel-van den Hurk S; Braun R P; Karvonen B C; King T; Yoo D; Babiuk L A
Immune responses and protection induced by DNA vaccines encoding bovine parainfluenza virus type 3 glycoproteins.
Virology 1999;260(1):35-46.
-
1999: Morsey M A; Van-Kessel A G; Mori Y; Popowych Y; Godson D; Campos M; Babiuk L A
Cytokine profiles following interaction between bovine alveolar macrophages and Pasteurella haemolytica.
Microbial pathogenesis 1999;26(6):325-31.
-
1999: Zakhartchouk A N; Pyne C; Mutwiri G K; Papp Z; Baca-Estrada M E; Griebel P; Babiuk L A; Tikoo S K
Mucosal immunization of calves with recombinant bovine adenovirus-3: induction of protective immunity to bovine herpesvirus-1.
The Journal of general virology 1999;80 ( Pt 5)():1263-9.
-
1999: Mittal S K; Tikoo S K; Van Donkersgoed J; Beskorwayne T; Godson D L; Babiuk L A
Experimental inoculation of heifers with bovine adenovirus type 3.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1999;63(2):153-6.
-
1999: Idamakanti N; Reddy P S; Babiuk L A; Tikoo S K
Transcription mapping and characterization of 284R and 121R proteins produced from early region 3 of bovine adenovirus type 3.
Virology 1999;256(2):351-9.
-
1999: Babiuk L A
Broadening the approaches to developing more effective vaccines.
Vaccine 1999;17(13-14):1587-95.
-
1999: Reddy P S; Idamakanti N; Hyun B H; Tikoo S K; Babiuk L A
Development of porcine adenovirus-3 as an expression vector.
The Journal of general virology 1999;80 ( Pt 3)():563-70.
-
1999: Wright P; Braun R; Babiuk L; Littel-van den Hurk S D; Moyana T; Zheng C; Chen Y; Xiang J
Adenovirus-mediated TNF-alpha gene transfer induces significant tumor regression in mice.
Cancer biotherapy & radiopharmaceuticals 1999;14(1):49-57.
-
1999: Papp Z; Babiuk L A; Baca-Estrada M E
The effect of pre-existing adenovirus-specific immunity on immune responses induced by recombinant adenovirus expressing glycoprotein D of bovine herpesvirus type 1.
Vaccine 1999;17(7-8):933-43.
-
1999: Reddy P S; Chen Y; Idamakanti N; Pyne C; Babiuk L A; Tikoo S K
Characterization of early region 1 and pIX of bovine adenovirus-3.
Virology 1999;253(2):299-308.
-
1999: Lewis P J; Babiuk L A
DNA vaccines: a review.
Advances in virus research 1999;54():129-88.
-
1999: Hegde N R; Deshpande M S; Godson D L; Babiuk L A; Srikumaran S
Bovine lymphocyte antigen-A11--specific peptide motif as a means to identify cytotoxic T-lymphocyte epitopes of bovine herpesvirus 1.
Viral immunology 1999;12(2):149-61.
-
1999: Papp Z; Babiuk L A; Baca-Estrada M E
Antigen-specific cytokine and antibody isotype profiles induced by mucosal and systemic immunization with recombinant adenoviruses.
Viral immunology 1999;12(2):107-16.
-
1999: Van Drunen Littel-van den Hurk S; Braun R P; Lewis P J; Karvonen B C; Babiuk L A; Griebel P J
Immunization of neonates with DNA encoding a bovine herpesvirus glycoprotein is effective in the presence of maternal antibodies.
Viral immunology 1999;12(1):67-77.
-
1999: Babiuk L A; Lewis J; van den Hurk S; Braun R
DNA immunization: present and future.
Advances in veterinary medicine 1999;41():163-79.
-
1998: Braun R; Babiuk L A; van Drunen Littel-van den Hurk
Compatibility of plasmids expressing different antigens in a single DNA vaccine formulation.
The Journal of general virology 1998;79 ( Pt 12)():2965-70.
-
1998: Reddy P S; Idamakanti N; Song J Y; Lee J B; Hyun B H; Park J H; Cha S H; Tikoo S K; Babiuk L A
Sequence and transcription map analysis of early region-1 of porcine adenovirus type-3.
Virus research 1998;58(1-2):97-106.
-
1998: Reddy P S; Idamakanti N; Song J Y; Lee J B; Hyun B H; Park J H; Cha S H; Bae Y T; Tikoo S K; Babiuk L A
Nucleotide sequence and transcription map of porcine adenovirus type 3.
Virology 1998;251(2):414-26.
-
1998: Zakhartchouk A N; Reddy P S; Baxi M; Baca-Estrada M E; Mehtali M; Babiuk L A; Tikoo S K
Construction and characterization of E3-deleted bovine adenovirus type 3 expressing full-length and truncated form of bovine herpesvirus type 1 glycoprotein gD.
Virology 1998;250(1):220-9.
-
1998: Foldvari M; Attah-Poku S; Hu J; Li Q; Hughes H; Babiuk L A; Kruger S
Palmitoyl derivatives of interferon alpha: potential for cutaneous delivery.
Journal of pharmaceutical sciences 1998;87(10):1203-8.
-
1998: Ijaz M K; Nur-E-Kamal M S; Dar F K; Uduman S; Redmond M J; Attah-Poku S K; Dent D; Babiuk L A
Inhibition of rotavirus infection in vitro and in vivo by a synthetic peptide from VP4.
Vaccine 1998;16(9-10):916-20.
-
1998: van Drunen Littel-van den Hurk; Braun R P; Lewis P J; Karvonen B C; Baca-Estrada M E; Snider M; McCartney D; Watts T; Babiuk L A
Intradermal immunization with a bovine herpesvirus-1 DNA vaccine induces protective immunity in cattle.
The Journal of general virology 1998;79 ( Pt 4)():831-9.
-
1998: Reddy P S; Idamakanti N; Zakhartchouk A N; Baxi M K; Lee J B; Pyne C; Babiuk L A; Tikoo S K
Nucleotide sequence, genome organization, and transcription map of bovine adenovirus type 3.
Journal of virology 1998;72(2):1394-402.
-
1998: Lee J; Babiuk L A; Yoo D
A neutralizing monoclonal antibody to bovine rotavirus VP8 neutralizes rotavirus infection without inhibiting virus attachment to MA-104 cells.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1998;62(1):63-7.
-
1998: Lee J; Yoo D; Redmond M J; Attah-Poku S K; van den Hurk J V; Babiuk L A
Characterization of the interaction between VP8 of bovine rotavirus C486 and cellular components on MA-104 cells and erythrocytes.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1998;62(1):56-62.
-
1998: Mittal S K; Tikoo S K; van den Hurk J V; Breker-Klassen M M; Yoo D; Babiuk L A
Functional characterization of bovine parainfluenza virus type 3 hemagglutinin-neuraminidase and fusion proteins expressed by adenovirus recombinants.
Intervirology 1998;41(6):253-60.
-
1998: Lee J B; Baxi M K; Idamakanti N; Reddy P S; Zakhartchouk A N; Pyne C; Babiuk L A; Tikoo S K
Genetic organization and DNA sequence of early region 4 of bovine adenovirus type 3.
Virus genes 1998;17(1):99-100.
-
1998: Papp Z; Babiuk L A; Baca-Estrada M E
Induction of immunity in the respiratory tract and protection from bovine herpesvirus type 1 infection by different routes of immunization with recombinant adenovirus.
Viral immunology 1998;11(2):79-91.
-
1998: Baxi M K; Reddy P S; Zakhartchouk A N; Idamakanti N; Pyne C; Babiuk L A; Tikoo S K
Characterization of bovine adenovirus type 3 early region 2B.
Virus genes 1998;16(3):313-6.
-
1998: Babiuk L A; Lewis P J; van Drunen Little-van den Hurk S; Tikoo S; Liang X
Nucleic acid vaccines: veterinary applications.
Current topics in microbiology and immunology 1998;226():90-106.
-
1997: Papp Z; Middleton D M; Mittal S K; Babiuk L A; Baca-Estrada M E
Mucosal immunization with recombinant adenoviruses: induction of immunity and protection of cotton rats against respiratory bovine herpesvirus type 1 infection.
The Journal of general virology 1997;78 ( Pt 11)():2933-43.
-
1997: Baca-Estrada M E; Foldvari M; Snider M; van Drunen Littel-van den Hurk S; Babiuk L A
Effect of IL-4 and IL-12 liposomal formulations on the induction of immune response to bovine herpesvirus type-1 glycoprotein D.
Vaccine 1997;15(16):1753-60.
-
1997: Liang X; Chow B; Babiuk L A
Study of immunogenicity and virulence of bovine herpesvirus 1 mutants deficient in the UL49 homolog, UL49.5 homolog and dUTPase genes in cattle.
Vaccine 1997;15(10):1057-64.
-
1997: Lewis P J; Cox G J; van Drunen Littel-van den Hurk S; Babiuk L A
Polynucleotide vaccines in animals: enhancing and modulating responses.
Vaccine 1997;15(8):861-4.
-
1997: Li Y; van Drunen Littel-van den Hurk S; Liang X; Babiuk L A
Functional analysis of the transmembrane anchor region of bovine herpesvirus 1 glycoprotein gB.
Virology 1997;228(1):39-54.
-
1997: van Drunen Littel-van den Hurk S; Tikoo S K; van den Hurk J V; Babiuk L A; Van Donkersgoed J
Protective immunity in cattle following vaccination with conventional and marker bovine herpesvirus-1 (BHV1) vaccines.
Vaccine 1997;15(1):36-44.
-
1997: Suradhat S; Yoo D; Babiuk L A; Griebel P; Baca-Estrada M E
DNA immunization with a bovine rotavirus VP4 gene induces a Th1-like immune response in mice.
Viral immunology 1997;10(3):117-27.
-
1997: Baca-Estrada M E; Babiuk L A; Yoo D
Hemagglutinin-esterase glycoprotein gene of bovine corona virus delivered by adenovirus vector induces mucosal immunity in cotton rats.
Advances in experimental medicine and biology 1997;412():431-3.
-
1996: Warren L M; Babiuk L A; Campos M
Effects of BHV-1 on PMN adhesion to bovine lung endothelial cells.
Veterinary immunology and immunopathology 1996;55(1-3):73-82.
-
1996: Babiuk L A; van Drunen Littel-van den Hurk S; Tikoo S K
Immunology of bovine herpesvirus 1 infection.
Veterinary microbiology 1996;53(1-2):31-42.
-
1996: Babiuk L A; van Drunen Littel-van den Hurk S; Tikoo S K; Lewis P J; Liang X
Novel viral vaccines for livestock.
Veterinary immunology and immunopathology 1996;54(1-4):355-63.
-
1996: Van Kessel A G; Godson D L; Baca-Estrada M E; Morsey M A; Hughes H P; Harland R; Shuster D E; Daley M J; Babiuk L A
Effect of recombinant bovine interleukin-1 beta in normal calves and in calves infected with bovine herpesvirus type 1.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(11):881-90.
-
1996: Mittal S K; Papp Z; Tikoo S K; Baca-Estrada M E; Yoo D; Benko M; Babiuk L A
Induction of systemic and mucosal immune responses in cotton rats immunized with human adenovirus type 5 recombinants expressing the full and truncated forms of bovine herpesvirus type 1 glycoprotein gD.
Virology 1996;222(2):299-309.
-
1996: Li Y; van Drunen Littel-van den Hurk S; Liang X; Babiuk L A
The cytoplasmic domain of bovine herpesvirus 1 glycoprotein B is important for maintaining conformation and the high-affinity binding site of gB.
Virology 1996;222(1):262-8.
-
1996: Breker-Klassen M M; Yoo D; Babiuk L A
Comparisons of the F and HN gene sequences of different strains of bovine parainfluenza virus type 3: relationship to phenotype and pathogenicity.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1996;60(3):228-36.
-
1996: van Drunen Littel-van den Hurk S; Khattar S; Tikoo S K; Babiuk L A; Baranowski E; Plainchamp D; Thiry E
Glycoprotein H (gII/gp108) and glycoprotein L form a functional complex which plays a role in penetration, but not in attachment, of bovine herpesvirus 1.
The Journal of general virology 1996;77 ( Pt 7)():1515-20.
-
1996: Raggo C; Fitzpatrick D R; Babiuk L A; Liang X
Expression of bovine interleukin-1 beta in a bovine herpesvirus-1 vector: in vitro analysis.
Virology 1996;221(1):78-86.
-
1996: Godson D L; Campos M; Attah-Poku S K; Redmond M J; Cordeiro D M; Sethi M S; Harland R J; Babiuk L A
Serum haptoglobin as an indicator of the acute phase response in bovine respiratory disease.
Veterinary immunology and immunopathology 1996;51(3-4):277-92.
-
1996: Jiang M; Babiuk L A; Potter A A
Cloning, sequencing and expression of the CAMP factor gene of Streptococcus uberis.
Microbial pathogenesis 1996;20(5):297-307.
-
1996: Khattar S K; van Drunen Littel-van den Harke S; Attah-Poku S K; Babiuk L A; Tikoo S K
Identification and characterization of a bovine herpesvirus-1 (BHV-1) glycoprotein gL which is required for proper antigenicity, processing, and transport of BHV-1 glycoprotein gH.
Virology 1996;219(1):66-76.
-
1996: Morsey M A; Popowych Y; Kowalski J; Gerlach G; Godson D; Campos M; Babiuk L A
Molecular cloning and expression of bovine interleukin-8.
Microbial pathogenesis 1996;20(4):203-12.
-
1996: Li Y; Liang X; van Drunen Littel-van den Hurk S; Attah-Poku S; Babiuk L A
Glycoprotein Bb, the N-terminal subunit of bovine herpesvirus 1 gB, can bind to heparan sulfate on the surfaces of Madin-Darby bovine kidney cells.
Journal of virology 1996;70(3):2032-7.
-
1996: Liang X; Chow B; Raggo C; Babiuk L A
Bovine herpesvirus 1 UL49.5 homolog gene encodes a novel viral envelope protein that forms a disulfide-linked complex with a second virion structural protein.
Journal of virology 1996;70(3):1448-54.
-
1996: Khadr A; Tikoo S K; Babiuk L A; van Drunen Littel-van den Hurk S
Sequence and expression of a bovine herpesvirus-1 gene homologous to the glycoprotein K-encoding gene of herpes simplex virus-1.
Gene 1996;168(2):189-93.
-
1996: Mittal S K; Middleton D M; Tikoo S K; Prevec L; Graham F L; Babiuk L A
Pathology and immunogenicity in the cotton rat (Sigmodon hispidus) model after infection with a bovine adenovirus type 3 recombinant virus expressing the firefly luciferase gene.
The Journal of general virology 1996;77 ( Pt 1)():1-9.
-
1996: Li Y; Van Drunen Littel-Van den Hurk S; Liang X; Babiuk L A
Production and characterization of bovine herpesvirus 1 glycoprotein B ectodomain derivatives in an hsp70A gene promoter-based expression system.
Archives of virology 1996;141(10):2019-29.
-
1996: Baca-Estrada M E; Snider M; Tikoo S K; Harland R; Babiuk L A; van Drunen Littel-van den Hurk S
Immunogenicity of bovine herpesvirus 1 glycoprotein D in mice: effect of antigen form on the induction of cellular and humoral immune responses.
Viral immunology 1996;9(1):11-22.
-
1995: Babiuk L A; Lewis P J; Cox G; van Drunen Littel-van den Hurk S; Baca-Estrada M; Tikoo S K
DNA immunization with bovine herpesvirus-1 genes.
Annals of the New York Academy of Sciences 1995;772():47-63.
-
1995: Godson D L; Baca-Estrada M E; Van Kessel A G; Hughes H P; Morsy M A; Van Donkersgoed J; Harland R J; Shuster D E; Daley M J; Babiuk L A
Regulation of bovine acute phase responses by recombinant interleukin-1 beta.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1995;59(4):249-55.
-
1995: Lee J; Babiuk L A; Harland R; Gibbons E; Elazhary Y; Yoo D
Immunological response to recombinant VP8* subunit protein of bovine roravirus in pregnant cattle.
The Journal of general virology 1995;76 ( Pt 10)():2477-83.
-
1995: Khattar S K; van Drunen Littel-van den Hurk S; Babiuk L A; Tikoo S K
Identification and transcriptional analysis of a 3'-coterminal gene cluster containing UL1, UL2, UL3, and UL3.5 open reading frames of bovine herpesvirus-1.
Virology 1995;213(1):28-37.
-
1995: Mittal S K; Middleton D M; Tikoo S K; Babiuk L A
Pathogenesis and immunogenicity of bovine adenovirus type 3 in cotton rats (Sigmodon hispidus).
Virology 1995;213(1):131-9.
-
1995: Baca-Estrada M E; Liang X; Babiuk L A; Yoo D
Induction of mucosal immunity in cotton rats to haemagglutinin-esterase glycoprotein of bovine coronavirus by recombinant adenovirus.
Immunology 1995;86(1):134-40.
-
1995: Li Y; van Drunen Littel-van den Hurk S; Babiuk L A; Liang X
Characterization of cell-binding properties of bovine herpesvirus 1 glycoproteins B, C, and D: identification of a dual cell-binding function of gB.
Journal of virology 1995;69(8):4758-68.
-
1995: Breker-Klassen M M; Yoo D; Mittal S K; Sorden S D; Haines D M; Babiuk L A
Recombinant type 5 adenoviruses expressing bovine parainfluenza virus type 3 glycoproteins protect Sigmodon hispidus cotton rats from bovine parainfluenza virus type 3 infection.
Journal of virology 1995;69(7):4308-15.
-
1995: Liang X; Chow B; Li Y; Raggo C; Yoo D; Attah-Poku S; Babiuk L A
Characterization of bovine herpesvirus 1 UL49 homolog gene and product: bovine herpesvirus 1 UL49 homolog is dispensable for virus growth.
Journal of virology 1995;69(6):3863-7.
-
1995: Ijaz M K; Alkarmi T O; Sabara M I; Frenchick P J; el Mekki A A; Naiem M; Nur-e-Kamal M S; Frossard P M; Dar F K; Babiuk L A
Characterization of a synthetic peptide mimicking trypsin-cleavage site of rotavirus VP4.
Comparative immunology, microbiology and infectious diseases 1995;18(3):145-60.
-
1995: Baca-Estrada M E; Godson D L; Hughes H P; Van Donkersgoed J; Van Kessel A; Harland R; Shuster D E; Daley M; Babiuk L A
Effect of recombinant bovine interleukin-1 beta on viral/bacterial pneumonia in cattle.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(5):431-9.
-
1995: Liang X; Pyne C; Li Y; Babiuk L A; Kowalski J
Delineation of the essential function of bovine herpesvirus 1 gD: an indication for the modulatory role of gD in virus entry.
Virology 1995;207(2):429-41.
-
1995: Ijaz M K; Alkarmi T O; el-Mekki A W; Galadari S H; Dar F K; Babiuk L A
Priming and induction of anti-rotavirus antibody response by synthetic peptides derived from VP7 and VP4.
Vaccine 1995;13(4):331-8.
-
1995: Mittal S K; Prevec L; Graham F L; Babiuk L A
Development of a bovine adenovirus type 3-based expression vector.
The Journal of general virology 1995;76 ( Pt 1)():93-102.
-
1995: van Drunen Littel-van den Hurk S; Garzon S; van den Hurk J V; Babiuk L A; Tijssen P
The role of the major tegument protein VP8 of bovine herpesvirus-1 in infection and immunity.
Virology 1995;206(1):413-25.
-
1995: Yoo D; Parker M D; Cox G J; Babiuk L A
Zinc-binding of the cysteine-rich domain encoded in the open reading frame of 1B of the RNA polymerase gene of coronavirus.
Advances in experimental medicine and biology 1995;380():437-42.
-
1995: Tikoo S K; Campos M; Popowych Y I; van Drunen Littel-van den Hurk S; Babiuk L A
Lymphocyte proliferative responses to recombinant bovine herpes virus type 1 (BHV-1) glycoprotein gD (gIV) in immune cattle: identification of a T cell epitope.
Viral immunology 1995;8(1):19-25.
-
1995: Tikoo S K; Campos M; Babiuk L A
Bovine herpesvirus 1 (BHV-1): biology, pathogenesis, and control.
Advances in virus research 1995;45():191-223.
-
1994: van Drunen Littel-van den Hurk S; Van Donkersgoed J; Kowalski J; van den Hurk J V; Harland R; Babiuk L A; Zamb T J
A subunit gIV vaccine, produced by transfected mammalian cells in culture, induces mucosal immunity against bovine herpesvirus-1 in cattle.
Vaccine 1994;12(14):1295-302.
-
1994: Hughes H P; Campos M; McDougall L; Beskorwayne T K; Potter A A; Babiuk L A
Regulation of major histocompatibility complex class II expression by Pasteurella haemolytica leukotoxin.
Infection and immunity 1994;62(5):1609-15.
-
1994: Ijaz M K; Sabara M I; Alkarmi T; Frenchick P J; Ready K F; Dar F K; Babiuk L A
Molecular determinants of rotavirus virulence: localization of a potential virulence site in a murine rotavirus VP4.
Comparative immunology, microbiology and infectious diseases 1994;17(2):99-110.
-
1994: Hughes H P; Rossow S; Campos M; Rossi-Campos A; Janssen S; Godson D L; Daflon B; Voirol M J; Gerber C; Babiuk L A
A slow release formulation for recombinant bovine interferon alpha I-1.
Antiviral research 1994;23(1):33-44.
-
1993: Ijaz M K; Sabara M I; Alkarmi T; Frenchick P J; Ready K F; Longson M; Dar F K; Babiuk L A
Characterization of two rotaviruses differing in their in vitro and in vivo virulence.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1993;55(6):963-71.
-
1993: van Drunen Littel-van den Hurk S; Tikoo S K; Liang X; Babiuk L A
Bovine herpesvirus-1 vaccines.
Immunology and cell biology 1993;71 ( Pt 5)():405-20.
-
1993: Cox G J; Zamb T J; Babiuk L A
Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA.
Journal of virology 1993;67(9):5664-7.
-
1993: Campos M; Godson D; Hughes H; Babiuk L; Sordillo L
The role of biological response modifiers in disease control.
Journal of dairy science 1993;76(8):2407-17.
-
1993: Liang X; Tang M; Zamb T J; Babiuk L A; Kowalski J; Tykocinski M L
Expression of glycoprotein gIII-human decay-accelerating factor chimera on the bovine herpesvirus 1 virion via a glycosyl phosphatidylinositol-based membrane anchor.
Journal of virology 1993;67(8):4896-904.
-
1993: Liang X; Tang M; Manns B; Babiuk L A; Zamb T J
Identification and deletion mutagenesis of the bovine herpesvirus 1 dUTPase gene and a gene homologous to herpes simplex virus UL49.5.
Virology 1993;195(1):42-50.
-
1993: Liang X; Babiuk L A; Zamb T J
Mapping of heparin-binding structures on bovine herpesvirus 1 and pseudorabies virus gIII glycoproteins.
Virology 1993;194(1):233-43.
-
1993: Tikoo S K; Zamb T J; Babiuk L A
Analysis of bovine herpesvirus 1 glycoprotein gIV truncations and deletions expressed by recombinant vaccinia viruses.
Journal of virology 1993;67(4):2103-9.
-
1993: Tikoo S K; Parker M D; van den Hurk J V; Kowalski J; Zamb T J; Babiuk L A
Role of N-linked glycans in antigenicity, processing, and cell surface expression of bovine herpesvirus 1 glycoprotein gIV.
Journal of virology 1993;67(2):726-33.
-
1993: Ellis J A; Godson D; Campos M; Sileghem M; Babiuk L A
Capture immunoassay for ruminant tumor necrosis factor-alpha: comparison with bioassay.
Veterinary immunology and immunopathology 1993;35(3-4):289-300.
-
1993: Redmond M J; Ijaz M K; Parker M D; Sabara M I; Dent D; Gibbons E; Babiuk L A
Assembly of recombinant rotavirus proteins into virus-like particles and assessment of vaccine potential.
Vaccine 1993;11(2):273-81.
-
1993: van Drunen Littel-van den Hurk S; Parker M D; Massie B; van den Hurk J V; Harland R; Babiuk L A; Zamb T J
Protection of cattle from BHV-1 infection by immunization with recombinant glycoprotein gIV.
Vaccine 1993;11(1):25-35.
-
1993: Kowalski J; Gilbert S A; van Drunen-Littel-van den Hurk S; van den Hurk J; Babiuk L A; Zamb T J
Heat-shock promoter-driven synthesis of secreted bovine herpesvirus glycoproteins in transfected cells.
Vaccine 1993;11(11):1100-7.
-
1992: Yoo D; Graham F L; Prevec L; Parker M D; Benkö M; Zamb T; Babiuk L A
Synthesis and processing of the haemagglutinin-esterase glycoprotein of bovine coronavirus encoded in the E3 region of adenovirus.
The Journal of general virology 1992;73 ( Pt 10)():2591-600.
-
1992: van Drunen Littel-van den Hurk S; Parker M D; Fitzpatrick D R; van den Hurk J V; Campos M; Babiuk L A; Zamb T
Structural, functional, and immunological characterization of bovine herpesvirus-1 glycoprotein gl expressed by recombinant baculovirus.
Virology 1992;190(1):378-92.
-
1992: Pfeifer C G; Campos M; Beskorwayne T; Babiuk L A; Potter A A
Effect of Haemophilus somnus on phagocytosis and hydrogen peroxide production by bovine polymorphonuclear leukocytes.
Microbial pathogenesis 1992;13(3):191-202.
-
1992: Liang X; Babiuk L A; Zamb T J
An in vivo study of a glycoprotein gIII-negative bovine herpesvirus 1 (BHV-1) mutant expressing beta-galactosidase: evaluation of the role of gIII in virus infectivity and its use as a vector for mucosal immunization.
Virology 1992;189(2):629-39.
-
1992: Campos M; Rossi C R; Bielefeldt Ohmann H; Beskorwayne T; Rapin N; Babiuk L A
Characterization and activation requirements of bovine lymphocytes acquiring cytotoxic activity after interleukin-2 treatment.
Veterinary immunology and immunopathology 1992;32(3-4):205-23.
-
1992: Schuh J C; Bielefeldt Ohmann H; Babiuk L A; Doige C E
Bovine herpesvirus-1-induced pharyngeal tonsil lesions in neonatal and weanling calves.
Journal of comparative pathology 1992;106(3):243-53.
-
1992: Xiang J; Pan Z; Attah-Poku S; Babiuk L; Zhang Y; Liu E
Production of hybrid bispecific antibody recognizing human colorectal carcinoma and CD3 antigen.
Molecular biotherapy 1992;4(1):15-23.
-
1992: Hughes H P; Campos M; Potter A A; Babiuk L A
Molecular chimerization of Pasteurella haemolytica leukotoxin to interleukin-2: effects on cytokine and antigen function.
Infection and immunity 1992;60(2):565-70.
-
1992: Sordillo L M; Snider M; Babiuk L A
Physiological and morphological changes in bovine mammary glands following intramammary infusion of recombinant interferon-gamma.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1992;56(1):22-7.
-
1992: Campos M; Hughes H P; Godson D L; Sordillo L M; Rossi-Campos A; Babiuk L A
Clinical and immunological effects of single bolus administration of recombinant interleukin-2 in cattle.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1992;56(1):10-5.
-
1992: Campos M; Griebel P; Bielefeldt Ohmann H; Babiuk L A
Cell-mediated cytotoxic responses in lungs following a primary bovine herpes virus type 1 infection.
Immunology 1992;75(1):47-52.
-
1992: Sordillo L M; Afseth G; Davies G; Babiuk L A
Effects of recombinant granulocyte-macrophage colony-stimulating factor on bovine peripheral blood and mammary gland neutrophil function in vitro.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1992;56(1):16-21.
-
1992: Hughes H P; Campos M; van Drunen Littel-van den Hurk S; Zamb T; Sordillo L M; Godson D; Babiuk L A
Multiple administration with interleukin-2 potentiates antigen-specific responses to subunit vaccination with bovine herpesvirus-1 glycoprotein IV.
Vaccine 1992;10(4):226-30.
-
1992: Frenchick P J; Sabara M I; Ready K F; Babiuk L A
Biochemical and immunological characterization of a novel peptide carrier system using rotavirus VP6 particles.
Vaccine 1992;10(11):783-91.
-
1992: Godson D L; Campos M; Babiuk L A
The role of bovine intraepithelial leukocyte-mediated cytotoxicity in enteric antiviral defense.
Viral immunology 1992;5(1):1-13.
-
1992: Hughes H P; Babiuk L A
The adjuvant potential of cytokines.
Biotechnology therapeutics 1992;3(3-4):101-17.
-
1991: Sordillo L M; Snider M; Hughes H; Afseth G; Campos M; Babiuk L A
Pathological changes in bovine mammary glands following intramammary infusion of recombinant interleukin-2.
Journal of dairy science 1991;74(12):4164-74.
-
1991: Babiuk L A; Sordillo L M; Campos M; Hughes H P; Rossi-Campos A; Harland R
Application of interferons in the control of infectious diseases of cattle.
Journal of dairy science 1991;74(12):4385-98.
-
1991: Cox G J; Parker M D; Babiuk L A
Bovine coronavirus nonstructural protein ns2 is a phosphoprotein.
Virology 1991;185(1):509-12.
-
1991: Hughes H P; Campos M; Godson D L; Van Drunen Littel-Van den Hurk S; McDougall L; Rapin N; Zamb T; Babiuk L A
Immunopotentiation of bovine herpes virus subunit vaccination by interleukin-2.
Immunology 1991;74(3):461-6.
-
1991: Sordillo L M; Campos M; Babiuk L A
Antibacterial activity of bovine mammary gland lymphocytes following treatment with interleukin-2.
Journal of dairy science 1991;74(10):3370-5.
-
1991: Godson D L; Campos M; Babiuk L A
Non-major histocompatibility complex-restricted cytotoxicity of bovine coronavirus-infected target cells mediated by bovine intestinal intraepithelial leukocytes.
The Journal of general virology 1991;72 ( Pt 10)():2457-65.
-
1991: Liang X P; Babiuk L A; Zamb T J
Pseudorabies virus gIII and bovine herpesvirus 1 gIII share complementary functions.
Journal of virology 1991;65(10):5553-7.
-
1991: Bielefeldt Ohmann H; Babiuk L A; Harland R
Cytokine synergy with viral cytopathic effects and bacterial products during the pathogenesis of respiratory tract infection.
Clinical immunology and immunopathology 1991;60(2):153-70.
-
1991: Yoo D W; Parker M D; Song J; Cox G J; Deregt D; Babiuk L A
Structural analysis of the conformational domains involved in neutralization of bovine coronavirus using deletion mutants of the spike glycoprotein S1 subunit expressed by recombinant baculoviruses.
Virology 1991;183(1):91-8.
-
1991: Sordillo L M; Babiuk L A
Controlling acute Escherichia coli mastitis during the periparturient period with recombinant bovine interferon gamma.
Veterinary microbiology 1991;28(2):189-98.
-
1991: Sordillo L M; Redmond M J; Campos M; Warren L; Babiuk L A
Cytokine activity in bovine mammary gland secretions during the periparturient period.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1991;55(3):298-301.
-
1991: Ijaz M K; Attah-Poku S K; Redmond M J; Parker M D; Sabara M I; Frenchick P; Babiuk L A
Heterotypic passive protection induced by synthetic peptides corresponding to VP7 and VP4 of bovine rotavirus.
Journal of virology 1991;65(6):3106-13.
-
1991: Redmond M J; Ohmann H B; Hughes H P; Sabara M; Frenchick P J; Poku S K; Ijaz M K; Parker M D; Laarveld B; Babiuk L A
Rotavirus particles function as immunological carriers for the delivery of peptides from infectious agents and endogenous proteins.
Molecular immunology 1991;28(3):269-78.
-
1991: Liang X P; Babiuk L A; van Drunen Littel-van den Hurk S; Fitzpatrick D R; Zamb T J
Bovine herpesvirus 1 attachment to permissive cells is mediated by its major glycoproteins gI, gIII, and gIV.
Journal of virology 1991;65(3):1124-32.
-
1991: Sordillo L M; Babiuk L A
Modulation of bovine mammary neutrophil function during the periparturient period following in vitro exposure to recombinant bovine interferon gamma.
Veterinary immunology and immunopathology 1991;27(4):393-402.
-
1991: Yoo D W; Parker M D; Babiuk L A
The S2 subunit of the spike glycoprotein of bovine coronavirus mediates membrane fusion in insect cells.
Virology 1991;180(1):395-9.
-
1991: van Drunen Littel-van den Hurk S; Parker M D; Fitzpatrick D R; Zamb T J; van den Hurk J V; Campos M; Harland R; Babiuk L A
Expression of bovine herpesvirus 1 glycoprotein gIV by recombinant baculovirus and analysis of its immunogenic properties.
Journal of virology 1991;65(1):263-71.
-
1991: Campos M; Ohmann H B; Rapin N; Babiuk L A
Demonstration of the in vitro antiviral properties of bovine lymphokine-activated killer (LAK) cells.
Viral immunology 1991;4(4):259-68.
-
1990: Yoo D; Parker M D; Babiuk L A
Analysis of the S spike (peplomer) glycoprotein of bovine coronavirus synthesized in insect cells.
Virology 1990;179(1):121-8.
-
1990: Tikoo S K; Fitzpatrick D R; Babiuk L A; Zamb T J
Molecular cloning, sequencing, and expression of functional bovine herpesvirus 1 glycoprotein gIV in transfected bovine cells.
Journal of virology 1990;64(10):5132-42.
-
1990: Hutchings D L; Campos M; Qualtiere L; Babiuk L A
Inhibition of antigen-induced and interleukin-2-induced proliferation of bovine peripheral blood leukocytes by inactivated bovine herpes virus 1.
Journal of virology 1990;64(9):4146-51.
-
1990: van Drunen Littel-van den Hurk S; Hughes G; Babiuk L A
The role of carbohydrate in the antigenic and immunogenic structure of bovine herpesvirus type 1 glycoproteins gI and gIV.
The Journal of general virology 1990;71 ( Pt 9)():2053-63.
-
1990: Parker M D; Yoo D; Cox G J; Babiuk L A
Primary Structure of the S peplomer gene of bovine coronavirus and surface expression in insect cells.
The Journal of general virology 1990;71 ( Pt 8)():1885.
-
1990: van Drunen Littel-van den Hurk S; Gifford G A; Babiuk L A
Epitope specificity of the protective immune response induced by individual bovine herpesvirus-1 glycoproteins.
Vaccine 1990;8(4):358-68.
-
1990: Fitzpatrick D R; Snider M; McDougall L; Beskorwayne T; Babiuk L A; Zamb T J; Bielefeldt Ohmann H
Molecular mimicry: a herpes virus glycoprotein antigenically related to a cell-surface glycoprotein expressed by macrophages, polymorphonuclear leucocytes, and platelets.
Immunology 1990;70(4):504-12.
-
1990: Fitzpatrick D R; Zamb T J; Babiuk L A
Expression of bovine herpesvirus type 1 glycoprotein gI in transfected bovine cells induces spontaneous cell fusion.
The Journal of general virology 1990;71 ( Pt 5)():1215-9.
-
1990: Fitzpatrick D R; Redmond M J; Attah-Poku S K; van Drunen Littel-van den Hurk S; Babiuk L A; Zamb T J
Mapping of 10 epitopes on bovine herpesvirus type 1 glycoproteins gI and gIII.
Virology 1990;176(1):145-57.
-
1990: Parker M D; Yoo D; Babiuk L A
Expression and secretion of the bovine coronavirus hemagglutinin-esterase glycoprotein by insect cells infected with recombinant baculoviruses.
Journal of virology 1990;64(4):1625-9.
-
1990: Griebel P J; Ohmann H B; Lawman M J; Babiuk L A
The interaction between bovine herpesvirus type 1 and activated bovine T lymphocytes.
The Journal of general virology 1990;71 ( Pt 2)():369-77.
-
1990: Parker M D; Yoo D; Cox G J; Babiuk L A
Primary structure of the S peplomer gene of bovine coronavirus and surface expression in insect cells.
The Journal of general virology 1990;71 ( Pt 2)():263-70.
-
1990: Ijaz M K; Dent D; Babiuk L A
Neuroimmunomodulation of in vivo anti-rotavirus humoral immune response.
Journal of neuroimmunology 1990;26(2):159-71.
-
1990: Ohmann H B; Campos M; McDougall L; Lawman M J; Babiuk L A
Expression of tumor necrosis factor-alpha receptors on bovine macrophages, lymphocytes and polymorphonuclear leukocytes, internalization of receptor-bound ligand, and some functional effects.
Lymphokine research 1990;9(1):43-58.
-
1990: Parker M D; Cox G J; Yoo D W; Fitzpatrick D R; Babiuk L A
The haemagglutinin of bovine coronavirus exhibits significant similarity to the haemagglutinin of type C influenza virus.
Advances in experimental medicine and biology 1990;276():103-8.
-
1989: Bielefeldt Ohmann H; Campos M; Snider M; Rapin N; Beskorwayne T; Popowych Y; Lawman M J; Rossi A; Babiuk L A
Effect of chronic administration of recombinant bovine tumor necrosis factor to cattle.
Veterinary pathology 1989;26(6):462-72.
-
1989: Fitzpatrick D R; Babiuk L A; Zamb T J
Nucleotide sequence of bovine herpesvirus type 1 glycoprotein gIII, a structural model for gIII as a new member of the immunoglobulin superfamily, and implications for the homologous glycoproteins of other herpesviruses.
Virology 1989;173(1):46-57.
-
1989: Nagi A M; Babiuk L A
Isolation, characterization and in vitro mitogenic stimulation of peripheral blood lymphocytes from an American buffalo.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1989;53(4):493-6.
-
1989: Ijaz M K; Dent D; Haines D; Babiuk L A
Development of a murine model to study the pathogenesis of rotavirus infection.
Experimental and molecular pathology 1989;51(2):186-204.
-
1989: Nagi A M; Babiuk L A
Interleukin-2 production by mitogen-stimulated intestinal mucosal leukocytes from cattle.
American journal of veterinary research 1989;50(9):1591-7.
-
1989: Griebel P J; Gee A P; Qualtiere L; Lawman M J; Babiuk L A
Negative enrichment of bovine T lymphocytes with monoclonal antibodies and magnetic microspheres.
Veterinary immunology and immunopathology 1989;22(2):161-73.
-
1989: Nagi A M; Babiuk L A
Peanut agglutinin (PNA): binding and stimulation of bovine intestinal and peripheral blood leukocytes.
Veterinary immunology and immunopathology 1989;22(1):67-78.
-
1989: Nagi A M; Babiuk L A
Characterization of surface markers of bovine gut mucosal leukocytes using monoclonal antibodies.
Veterinary immunology and immunopathology 1989;22(1):1-14.
-
1989: Nagi A M; Babiuk L A
Concanavalin A-induced suppressor cell activity in intestinal mucosal leukocytes obtained from healthy cows.
American journal of veterinary research 1989;50(8):1266-71.
-
1989: Cox G J; Parker M D; Babiuk L A
The sequence of cDNA of bovine coronavirus 32K nonstructural gene.
Nucleic acids research 1989;17(14):5847.
-
1989: van Drunen Littel-van den Hurk S; Zamb T; Babiuk L A
Synthesis, cellular location, and immunogenicity of bovine herpesvirus 1 glycoproteins gI and gIII expressed by recombinant vaccinia virus.
Journal of virology 1989;63(5):2159-68.
-
1989: Ohmann H B; Campos M; Fitzpatrick D R; Rapin N; Babiuk L A
A neutrophil-derived antiviral protein: induction requirements and biological properties.
Journal of virology 1989;63(5):1916-23.
-
1989: Griebel P J; Bielefeldt Ohmann H; Campos M; Qualtiere L; Davis W C; Lawman M J; Babiuk L A
Bovine peripheral blood leukocyte population dynamics following treatment with recombinant bovine interferon-alpha I1.
Journal of interferon research 1989;9(2):245-57.
-
1989: Bielefeldt Ohmann H; Campos M; Harland R; Griebel P J; Babiuk L A
2',5' oligoadenylate synthetase activity in bovine peripheral blood mononuclear cells following bovine herpesvirus type-1-induced respiratory disease: a prognostic indicator?
Journal of interferon research 1989;9(2):159-66.
-
1989: Ohmann H B; Campos M; Griebel P J; Babiuk L A
2'-5' oligo-A-synthetase activity in bovine peripheral blood leukocytes and alveolar macrophages exposed to recombinant interferons and tumor necrosis factor-alpha.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1989;53(2):161-6.
-
1989: Campos M; Ohmann H B; Hutchings D; Rapin N; Babiuk L A; Lawman M J
Role of interferon-gamma in inducing cytotoxicity of peripheral blood mononuclear leukocytes to bovine herpesvirus type 1 (BHV-1)-infected cells.
Cellular immunology 1989;120(1):259-69.
-
1989: Deregt D; Gifford G A; Ijaz M K; Watts T C; Gilchrist J E; Haines D M; Babiuk L A
Monoclonal antibodies to bovine coronavirus glycoproteins E2 and E3: demonstration of in vivo virus-neutralizing activity.
The Journal of general virology 1989;70 ( Pt 4)():993-8.
-
1989: Deregt D; Parker M D; Cox G C; Babiuk L A
Mapping of neutralizing epitopes to fragments of the bovine coronavirus E2 protein by proteolysis of antigen-antibody complexes.
The Journal of general virology 1989;70 ( Pt 3)():647-58.
-
1989: Nagi A M; Babiuk L A
Recombinant human interleukin-2-induced mitogenic proliferation of in vitro unstimulated bovine intestinal lymphocytes.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1989;53(1):68-75.
-
1989: Parker M D; Cox G J; Deregt D; Fitzpatrick D R; Babiuk L A
Cloning and in vitro expression of the gene for the E3 haemagglutinin glycoprotein of bovine coronavirus.
The Journal of general virology 1989;70 ( Pt 1)():155-64.
-
1988: Campos M; Ohmann H B; Hughes G; Babiuk L A; Lawman M J
Studies on the in vitro biological activities of recombinant bovine tumor necrosis factor (rBoTNF) alpha. I. Synergistic antiviral efficacy of rBoTNF alpha, recombinant bovine interferon gamma (rBoIFN gamma) and their combination.
Antiviral research 1988;10(1-3):71-81.
-
1988: Ready K F; Sabara M I; Babiuk L A
In vitro assembly of the outer capsid of bovine rotavirus is calcium-dependent.
Virology 1988;167(1):269-73.
-
1988: Fitzpatrick D R; Zamb T; Parker M D; van Drunen Littel-van den Hurk S; Babiuk L A; Lawman M J
Expression of bovine herpesvirus 1 glycoproteins gI and gIII in transfected murine cells.
Journal of virology 1988;62(11):4239-48.
-
1988: Nagi A M; Babiuk L A
Modulation of some Peyer's patch leukocyte functions following in vitro exposure to recombinant bovine alpha- and gamma-interferon.
Immunobiology 1988;177(4-5):329-38.
-
1988: Nagi A M; Babiuk L A
Effects of recombinant bovine interferons-alpha and -gamma on some in vitro immune functions of bovine intraepithelial and lamina propria leukocytes.
Journal of interferon research 1988;8(4):495-505.
-
1988: Ohmann H B; Campos M; Lawman M J; Babiuk L A
Induction of MHC class II antigens on bovine cells of nonlymphoid origin by recombinant bovine interferon-gamma and tumor necrosis factor-alpha.
Journal of interferon research 1988;8(4):451-62.
-
1988: Nagi A M; Babiuk L A
Response of bovine intestinal leukocytes to recombinant bovine interleukin-2.
Journal of biological regulators and homeostatic agents 1988;2(3):125-33.
-
1988: Bielefeldt Ohmann H; Babiuk L A
Influence of interferons alpha I1 and gamma and of tumour necrosis factor on persistent infection with bovine viral diarrhoea virus in vitro.
The Journal of general virology 1988;69 ( Pt 6)():1399-403.
-
1988: Nagi A M; Babiuk L A
Preparation, purification and characterization of bovine Peyer's patch leukocytes.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1988;52(2):249-57.
-
1988: Bielefeldt-Ohmann H; Sabara M; Lawman M J; Griebel P; Babiuk L A
A monoclonal antibody detects macrophage maturation antigen which appears independently of class II antigen expression. Reactivity of monoclonal EBM11 with bovine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2201-9.
-
1988: Ohmann H B; Babiuk L A
Induction of receptors for complement and immunoglobulins by herpesviruses of various species.
Virus research 1988;9(4):335-42.
-
1988: Babiuk L A; Lawman M J; Ohmann H B
Viral-bacterial synergistic interaction in respiratory disease.
Advances in virus research 1988;35():219-49.
-
1988: Hughes G; Babiuk L A; van Drunen Littel-van den Hurk S
Functional and topographical analyses of epitopes on bovine herpesvirus type 1 glycoprotein IV.
Archives of virology 1988;103(1-2):47-60.
-
1987: Nagi A M; Babiuk L A
Bovine gut-associated lymphoid tissue--morphologic and functional studies. I. Isolation and characterization of leukocytes from the epithelium and lamina propria of bovine small intestine.
Journal of immunological methods 1987;105(1):23-37.
-
1987: Lawman M J; Gifford G; Gyongyossy-Issa M; Dragan R; Heise J; Babiuk L A
Activity of polymorphonuclear (PMN) leukocytes during bovine herpes virus-1 induced respiratory disease: effect of recombinant bovine interferon alpha I1.
Antiviral research 1987;8(5-6):225-37.
-
1987: Ijaz M K; Sabara M I; Frenchick P J; Babiuk L A
Effect of different routes of immunization with bovine rotavirus on lactogenic antibody response in mice.
Antiviral research 1987;8(5-6):283-97.
-
1987: Deregt D; Babiuk L A
Monoclonal antibodies to bovine coronavirus: characteristics and topographical mapping of neutralizing epitopes on the E2 and E3 glycoproteins.
Virology 1987;161(2):410-20.
-
1987: Deregt D; Sabara M; Babiuk L A
Structural proteins of bovine coronavirus and their intracellular processing.
The Journal of general virology 1987;68 ( Pt 11)():2863-77.
-
1987: Ijaz M K; Sabara M I; Frenchick P J; Babiuk L A
Assessment of intestinal damage in rotavirus infected neonatal mice by a D-xylose absorption test.
Journal of virological methods 1987;18(2-3):153-7.
-
1987: Griebel P J; Schoonderwoerd M; Babiuk L A
Ontogeny of the immune response: effect of protein energy malnutrition in neonatal calves.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1987;51(4):428-35.
-
1987: Mechor G D; Rousseaux C G; Radostits O M; Babiuk L A; Petrie L
Protection of newborn calves against fatal multisystemic infectious bovine rhinotracheitis by feeding colostrum from vaccinated cows.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1987;51(4):452-9.
-
1987: Ohmann H B; Baker P E; Babiuk L A
Effect of dexamethasone on bovine leukocyte functions and bovine herpesvirus type-1 replication.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1987;51(3):350-7.
-
1987: Ohmann H B; Lawman M J; Babiuk L A
Bovine interferon: its biology and application in veterinary medicine.
Antiviral research 1987;7(4):187-210.
-
1987: Sabara M; Ready K F; Frenchick P J; Babiuk L A
Biochemical evidence for the oligomeric arrangement of bovine rotavirus nucleocapsid protein and its possible significance in the immunogenicity of this protein.
The Journal of general virology 1987;68 ( Pt 1)():123-33.
-
1987: Griebel P J; Qualtiere L; Davis W C; Gee A; Bielefeldt Ohmann H; Lawman M J; Babiuk L A
T lymphocyte population dynamics and function following a primary bovine herpesvirus type-1 infection.
Viral immunology 1987;1(4):287-304.
-
1987: Griebel P J; Qualtiere L; Davis W C; Lawman M J; Babiuk L A
Bovine peripheral blood leukocyte subpopulation dynamics following a primary bovine herpesvirus-1 infection.
Viral immunology 1987;1(4):267-86.
-
1987: Deregt D; Sabara M; Babiuk L A
Monoclonal antibodies to two bovine coronavirus glycoproteins neutralize virus infectivity.
Advances in experimental medicine and biology 1987;218():473-4.
-
1987: Lawman M J; Griebel P; Hutchings D L; Davis W C; Heise J; Qualtiere L; Babiuk L A
Generation of IL-2 dependent bovine cytotoxic T lymphocyte clones reactive against BHV-1 infected target cells: loss of genetic restriction and virus specificity.
Viral immunology 1987;1(3):163-76.
-
1985: Babiuk L A; Sabara M; Hudson G R
Rotavirus and coronavirus infections in animals.
Progress in veterinary microbiology and immunology 1985;1():80-120.
-
1982: Sabara M; Deregt D; Babiuk L A; Misra V
Genetic heterogeneity within individual bovine rotavirus isolates.
Journal of virology 1982;44(3):813-22.
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