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Lorne Babiuk

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Hani Boshra; Volker Gerdts; Pravesh Kara; Arshad Mather; Charles K Nfon; Suresh Tikoo; Thang Truong; David Wallace; Lorne A Babiuk; Shawn Babiuk
Capripoxvirus-vectored vaccines against livestock diseases in Africa.
Gael Auray; Lorne A Babiuk; Rachelle Buchanan; Marina R Facci; Jill van Kessel; Volker Gerdts
Porcine Neonatal Blood Dendritic Cells, but Not Monocytes, Are More Responsive to TLRs Stimulation than Their Adult Counterparts.
srinivas garlapati; Volker Gerdts; R E W Hancock; Laura Latimer; Andrew Potter; Elemir Simko; Lorne A Babiuk; Robert Brownlie; R Garg; Sylvia van Drunen Littel-van den Hurk
Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles.

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All Publications

2013: Hani Boshra; Volker Gerdts; Pravesh Kara; Arshad Mather; Charles K Nfon; Suresh Tikoo; Thang Truong; David Wallace; Lorne A Babiuk; Shawn Babiuk
Capripoxvirus-vectored vaccines against livestock diseases in Africa.
Antiviral research 2013;98(2):217-27.
2013: Gael Auray; Lorne A Babiuk; Rachelle Buchanan; Marina R Facci; Jill van Kessel; Volker Gerdts
Porcine Neonatal Blood Dendritic Cells, but Not Monocytes, Are More Responsive to TLRs Stimulation than Their Adult Counterparts.
PloS one 2013;8(5):e59629.
2012: srinivas garlapati; Volker Gerdts; R E W Hancock; Laura Latimer; Andrew Potter; Elemir Simko; Lorne A Babiuk; Robert Brownlie; R Garg; Sylvia van Drunen Littel-van den Hurk
Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles.
Vaccine 2012;30(35):5206-14.
2012: Natalya L Vasilenko; Lorne A Babiuk; Shaunivan L Labiuk; Vladislav A Lobanov; Marlene Snider; Sylvia van Drunen Littel-van den Hurk
Bovine herpesvirus-1 VP8 interacts with DNA damage binding protein-1 (DDB1) and is monoubiquitinated during infection.
Virus research 2012;167(1):56-66.
2012: Sunita Awate; Lorne A Babiuk; Ken Lai; Heather L Wilson; George K Mutwiri
Activation of adjuvant core response genes by the novel adjuvant PCEP.
Molecular immunology 2012;51(3-4):292-303.
2012: Arshud Dar; Donna Dent; Volker Gerdts; Ken Lai; Lorne A Babiuk; Andrew Potter; George K Mutwiri
Administration of poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs.
Veterinary immunology and immunopathology 2012;146(3-4):289-95.
2012: Rachelle Buchanan; Crystal Dagenais; Philip J Griebel; George K Mutwiri; Yurij Popowych; Andrew A Potter; Natasa Arsic; Lorne A Babiuk; H Wilson
Interferon-gamma and B-cell Activating Factor (BAFF) promote bovine B cell activation independent of TLR9 and T-cell signaling.
Veterinary immunology and immunopathology 2012;145(1-2):453-63.
2011: Tadele G Kiros; Jill van Kessel; Lorne A Babiuk; Volker Gerdts
Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC, thymus, and lung lymphocytes of young pigs.
Veterinary immunology and immunopathology 2011;144(3-4):448-54.
2011: Monika Polewicz; Andrew A Potter; Stacy Strom; Lorne A Babiuk; Rachelle Buchanan; Aleksandra Gracia; Scott A Halperin; Volker Gerdts
Influence of maternal antibodies on active pertussis toxoid immunization of neonatal mice and piglets.
Vaccine 2011;29(44):7718-26.
2011: A Landi; Lorne A Babiuk; Hong Yu; Sylvia van Drunen Littel-van den Hurk
Human dendritic cells expressing hepatitis C virus core protein display transcriptional and functional changes consistent with maturation.
Journal of viral hepatitis 2011;18(10):700-13.
2011: Sarah Mackenzie-Dyck; Sam Attah-Poku; Lorne A Babiuk; Veronique Juillard; Sylvia van Drunen Littel-van den Hurk
The synthetic peptides bovine enteric β-defensin (EBD), bovine neutrophil β-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells.
Veterinary immunology and immunopathology 2011;143(1-2):87-107.
2011: srinivas garlapati; Lorne A Babiuk; Nelson F Eng; Scott A Halperin; Robert E W Hancock; Jason Kindrachuk; Tadele G Kiros; George K Mutwiri; Andrew A Potter; Volker Gerdts
Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis.
Vaccine 2011;29(38):6540-8.
2011: Abdolamir Landi; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Dendritic cells matured by a prostaglandin E2-containing cocktail can produce high levels of IL-12p70 and are more mature and Th1-biased than dendritic cells treated with TNF-α or LPS.
Immunobiology 2011;216(6):649-62.
2011: Shawn Babiuk; Aleksandar Masic; Jill Graham; James Neufeld; Melanie van der Loop; John Copps; Yohannes Berhane; John Pasick; Andy Potter; Lorne A Babiuk; Hana Weingartl; Yan Zhou
An elastase-dependent attenuated heterologous swine influenza virus protects against pandemic H1N1 2009 influenza challenge in swine.
Vaccine 2011;29(17):3118-23.
2011: Aleksandra Gracia; Monika Polewicz; Scott A Halperin; Robert E W Hancock; Andrew A Potter; Lorne A Babiuk; Volker Gerdts
Antibody responses in adult and neonatal BALB/c mice to immunization with novel Bordetella pertussis vaccine formulations.
Vaccine 2011;29(8):1595-604.
2011: Rachelle M Buchanan; Philip J Griebel; George K Mutwiri; Yurij Popowych; Andrew A Potter; Hugh G G Townsend; Natasha Arsic; Lorne A Babiuk; H Wilson
B-cell activating factor (BAFF) promotes CpG ODN-induced B cell activation and proliferation.
Cellular immunology 2011;271(1):16-28.
2011: George Mutwiri; Volker Gerdts; Sylvia van Drunen Littel-van den Hurk; Gael Auray; Nelson Eng; srinivas garlapati; Lorne A Babiuk; Andrew Potter
Combination adjuvants: the next generation of adjuvants?
Expert review of vaccines 2011;10(1):95-107.
2011: Sarah E Forgie; Julia Keenliside; Craig Wilkinson; Richard Webby; Patricia Lu; Ole Sorensen; Kevin Fonseca; Subrata Barman; Adam Rubrum; Evelyn Stigger; Thomas J Marrie; Frank Marshall; Donald W Spady; Jia Hu; Mark Loeb; Margaret L Russell; Lorne A Babiuk
Swine outbreak of pandemic influenza A virus on a Canadian research farm supports human-to-swine transmission.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011;52(1):10-8.
2011: Jason Kindrachuk; Erin Scruten; Sam Attah-Poku; Kelli Bell; Andrew Potter; Lorne A Babiuk; Philip J Griebel; Scott Napper
Stability, toxicity, and biological activity of host defense peptide BMAP28 and its inversed and retro-inversed isomers.
Biopolymers 2011;96(1):14-24.
2010: srinivas garlapati; Nelson F Eng; Heather L Wilson; Rachelle Buchanan; George K Mutwiri; Lorne A Babiuk; Volker Gerdts
PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice.
Vaccine 2010;28(52):8306-14.
2010: Anil K Nichani; M Arshad Dar; Kuldip K Mirakhur; Arthur M Krieg; Jayaum S Booth; Hugh G G Townsend; Andrew A Potter; Lorne A Babiuk; George K Mutwiri
Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs.
Comparative immunology, microbiology and infectious diseases 2010;33(6):e111-7.
2010: Zhonghua Xiang; Ling Qiao; Yan Zhou; Lorne A Babiuk; Qiang Liu
Hepatitis C virus nonstructural protein-5A activates sterol regulatory element-binding protein-1c through transcription factor Sp1.
Biochemical and biophysical research communications 2010;402(3):549-53.
2010: Aleksandar Masic; Xinya Lu; Junwei Li; George K Mutwiri; Lorne A Babiuk; Earl G Brown; Yan Zhou
Immunogenicity and protective efficacy of an elastase-dependent live attenuated swine influenza virus vaccine administered intranasally in pigs.
Vaccine 2010;28(43):7098-108.
2010: Gael Auray; Marina R Facci; Jill van Kessel; Rachelle Buchanan; Lorne A Babiuk; Volker Gerdts
Differential activation and maturation of two porcine DC populations following TLR ligand stimulation.
Molecular immunology 2010;47(11-12):2103-11.
2010: Jayaum S Booth; Joram J Buza; Andrew Potter; Lorne A Babiuk; George K Mutwiri
Co-stimulation with TLR7/8 and TLR9 agonists induce down-regulation of innate immune responses in sheep blood mononuclear and B cells.
Developmental and comparative immunology 2010;34(5):572-8.
2010: Shaunivan L Labiuk; Vladislav Lobanov; Zoe Lawman; Marlene Snider; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Bovine herpesvirus-1 US3 protein kinase: critical residues and involvement in the phosphorylation of VP22.
The Journal of general virology 2010;91(Pt 5):1117-26.
2010: Erin Scruten; Jennifer Kovacs-Nolan; Philip J Griebel; Laura Latimer; Jason Kindrachuk; Andy Potter; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk; Scott Napper
Retro-inversion enhances the adjuvant and CpG co-adjuvant activity of host defence peptide Bac2A.
Vaccine 2010;28(17):2945-56.
2010: Arshud Dar; Anil Nichani; Ken Lai; Andy Potter; Volker Gerdts; Lorne A Babiuk; George Mutwiri
All three classes of CpG ODNs up-regulate IP-10 gene in pigs.
Research in veterinary science 2010;88(2):242-50.
2010: Doo-Hee Shim; Hyun-Jeong Ko; Gerdts Volker; Andrew A Potter; George Mutwiri; Lorne A Babiuk; Mi-Na Kweon
Efficacy of poly[di(sodium carboxylatophenoxy)phosphazene] (PCPP) as mucosal adjuvant to induce protective immunity against respiratory pathogens.
Vaccine 2010;28(11):2311-7.
2010: Peter D Hedlin; Neil R Cashman; Li Li; Jyotsana Gupta; Lorne A Babiuk; Andrew A Potter; Philip J Griebel; Scott Napper
Design and delivery of a cryptic PrP(C) epitope for induction of PrP(Sc)-specific antibody responses.
Vaccine 2010;28(4):981-8.
2010: Vladislav A Lobanov; C Zheng; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Intracellular trafficking of VP22 in bovine herpesvirus-1 infected cells.
Virology 2010;396(2):189-202.
2010: Nelson F Eng; srinivas garlapati; Volker Gerdts; Lorne A Babiuk; George K Mutwiri
PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens.
Journal of immune based therapies and vaccines 2010;8():4.
2010: Jayaum S Booth; Ryan Arsenault; Scott Napper; Philip J Griebel; Andrew A Potter; Lorne A Babiuk; George K Mutwiri
TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides.
Journal of innate immunity 2010;2(5):483-94.
2010: John W Mapletoft; Laura Latimer; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Intranasal immunization of mice with a bovine respiratory syncytial virus vaccine induces superior immunity and protection compared to those by subcutaneous delivery or combinations of intranasal and subcutaneous prime-boost strategies.
Clinical and vaccine immunology : CVI 2010;17(1):23-35.
2010: Vladislav A Lobanov; Sheryl L Maher-Sturgess; Marlene G Snider; Zoe Lawman; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
A UL47 gene deletion mutant of bovine herpesvirus type 1 exhibits impaired growth in cell culture and lack of virulence in cattle.
Journal of virology 2010;84(1):445-58.
2010: Nelson F Eng; srinivas garlapati; Volker Gerdts; Andrew Potter; Lorne A Babiuk; George K Mutwiri
The potential of polyphosphazenes for delivery of vaccine antigens and immunotherapeutic agents.
Current drug delivery 2010;7(1):13-20.
2009: Ryan J Arsenault; Shakiba Jalal; Lorne A Babiuk; Andrew Potter; Philip J Griebel; Scott Napper
Kinome analysis of Toll-like receptor signaling in bovine monocytes.
Journal of receptor and signal transduction research 2009;29(6):299-311.
2009: Shaunivan L Labiuk; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Major tegument protein VP8 of bovine herpesvirus 1 is phosphorylated by viral US3 and cellular CK2 protein kinases.
The Journal of general virology 2009;90(Pt 12):2829-39.
2009: Alexander K Andrianov; Daniel P DeCollibus; Helice A Gillis; Henry H Kha; Alexander Marin; Mark R Prausnitz; Lorne A Babiuk; Hugh Townsend; George Mutwiri
Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(45):18936-41.
2009: Sherry J Hannon; Brenda Allan; Cheryl Waldner; Margaret L Russell; Andrew Potter; Lorne A Babiuk; Hugh G G Townsend
Prevalence and risk factor investigation of Campylobacter species in beef cattle feces from seven large commercial feedlots in Alberta, Canada.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 2009;73(4):275-82.
2009: Aleksandar Masic; Jayaum S Booth; George K Mutwiri; Lorne A Babiuk; Yan Zhou
Elastase-dependent live attenuated swine influenza A viruses are immunogenic and confer protection against swine influenza A virus infection in pigs.
Journal of virology 2009;83(19):10198-210.
2009: Robert Brownlie; Jianzhong Zhu; Brenda Allan; George K Mutwiri; Lorne A Babiuk; Andrew Potter; Philip J Griebel
Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides.
Molecular immunology 2009;46(15):3163-70.
2009: Jennifer Kovacs-Nolan; John W Mapletoft; Z Lawman; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Formulation of bovine respiratory syncytial virus fusion protein with CpG oligodeoxynucleotide, cationic host defence peptide and polyphosphazene enhances humoral and cellular responses and induces a protective type 1 immune response in mice.
The Journal of general virology 2009;90(Pt 8):1892-905.
2009: Jason Kindrachuk; Håvard Jenssen; Melissa Elliott; Rebecca Townsend; Anastasia Nijnik; Song F Lee; Volker Gerdts; Lorne A Babiuk; Scott A Halperin; Robert E W Hancock
A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity.
Vaccine 2009;27(34):4662-71.
2009: Arshud Dar; Andrew Potter; Suresh Kumar Tikoo; Volker Gerdts; Ken Lai; Lorne A Babiuk; George K Mutwiri
CpG oligodeoxynucleotides activate innate immune response that suppresses infectious bronchitis virus replication in chicken embryos.
Avian diseases 2009;53(2):261-7.
2009: Palok Aich; Lorne A Babiuk; Andrew A Potter; Philip J Griebel
Biomarkers for prediction of bovine respiratory disease outcome.
Omics : a journal of integrative biology 2009;13(3):199-209.
2009: J S Booth; Philip J Griebel; Lorne A Babiuk; George K Mutwiri
A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses.
Mucosal immunology 2009;2(3):265-75.
2009: George Mutwiri; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk
Approaches to enhancing immune responses stimulated by CpG oligodeoxynucleotides.
Advanced drug delivery reviews 2009;61(3):226-32.
2009: Jennifer Kovacs-Nolan; Laura Latimer; A Landi; H Jenssen; R E W Hancock; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
The novel adjuvant combination of CpG ODN, indolicidin and polyphosphazene induces potent antibody- and cell-mediated immune responses in mice.
Vaccine 2009;27(14):2055-64.
2009: Jennifer Kovacs-Nolan; John W Mapletoft; Laura Latimer; Lorne A Babiuk; S van Drunen Littel-van den Hurk
CpG oligonucleotide, host defense peptide and polyphosphazene act synergistically, inducing long-lasting, balanced immune responses in cattle.
Vaccine 2009;27(14):2048-54.
2009: srinivas garlapati; Marina Facci; Monika Polewicz; Stacy Strom; Lorne A Babiuk; George K Mutwiri; Robert E W Hancock; Melissa R Elliott; Volker Gerdts
Strategies to link innate and adaptive immunity when designing vaccine adjuvants.
Veterinary immunology and immunopathology 2009;128(1-3):184-91.
2009: Frank H Gaertner; Lorne A Babiuk; George Mutwiri; Janna M Armstrong; Philip J Griebel
Amended recombinant cells (ARCs) expressing bovine IFN-gamma: an economical and highly effective adjuvant system.
Vaccine 2009;27(9):1377-85.
2009: Aleksandar Masic; Lorne A Babiuk; Yan Zhou
Reverse genetics-generated elastase-dependent swine influenza viruses are attenuated in pigs.
The Journal of general virology 2009;90(Pt 2):375-85.
2009: Jianzhong Zhu; Sylvia van Drunen Littel-van den Hurk; Robert Brownlie; Lorne A Babiuk; Andrew Potter; George K Mutwiri
Multiple molecular regions confer intracellular localization of bovine Toll-like receptor 8.
Molecular immunology 2009;46(5):884-92.
2009: Jianzhong Zhu; Robert Brownlie; Qiang Liu; Lorne A Babiuk; Andrew Potter; George K Mutwiri
Characterization of bovine Toll-like receptor 8: ligand specificity, signaling essential sites and dimerization.
Molecular immunology 2009;46(5):978-90.
2009: Shakiba Jalal; Ryan Arsenault; Andrew A Potter; Lorne A Babiuk; Philip J Griebel; Scott Napper
Genome to kinome: species-specific peptide arrays for kinome analysis.
Science signaling 2009;2(54):pl1.
2009: Xin-Ming Song; Wayne Connor; Karsten Hokamp; Lorne A Babiuk; Andrew A Potter
The growth phase-dependent regulation of the pilus locus genes by two-component system TCS08 in Streptococcus pneumoniae.
Microbial pathogenesis 2009;46(1):28-35.
2009: Xin-Ming Song; Wayne Connor; Karsten Hokamp; Lorne A Babiuk; Andrew A Potter
Transcriptome studies on Streptococcus pneumoniae, illustration of early response genes to THP-1 human macrophages.
Genomics 2009;93(1):72-82.
2008: Joram Buza; Ponn Benjamin; Jianzhung Zhu; H Wilson; Grayson Lipford; Arthur M Krieg; Lorne A Babiuk; George K Mutwiri
CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands.
Veterinary immunology and immunopathology 2008;126(3-4):273-82.
2008: Shokrollah Elahi; David R Thompson; Stacy Strom; Brendan O'Connor; Lorne A Babiuk; Volker Gerdts
Infection with Bordetella parapertussis but not Bordetella pertussis causes pertussis-like disease in older pigs.
The Journal of infectious diseases 2008;198(3):384-92.
2008: Arshud Dar; Anil K Nichani; Ponn Benjamin; Ken Lai; HW Soita; Arthur M Krieg; Andrew Potter; Lorne A Babiuk; George K Mutwiri
Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNalpha-producing cells and TLR9 mRNA expression.
Veterinary immunology and immunopathology 2008;123(3-4):324-36.
2008: Sylvia van Drunen Littel-van den Hurk; Marlene Snider; P Thompson; Laura Latimer; Lorne A Babiuk
Strategies for induction of protective immunity to bovine herpesvirus-1 in newborn calves with maternal antibodies.
Vaccine 2008;26(25):3103-11.
2008: Jason Kindrachuk; Jean Potter; H Wilson; Philip J Griebel; Lorne A Babiuk; Scott Napper
Activation and regulation of toll-like receptor 9: CpGs and beyond.
Mini reviews in medicinal chemistry 2008;8(6):590-600.
2008: Jianzhong Zhu; Ken Lai; Robert Brownile; Lorne A Babiuk; George K Mutwiri
Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod.
Molecular immunology 2008;45(11):3238-43.
2008: Hong Yu; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Strategies for loading dendritic cells with hepatitis C NS5a antigen and inducing protective immunity.
Journal of viral hepatitis 2008;15(6):459-70.
2008: George K Mutwiri; Ponn Benjamin; HW Soita; Lorne A Babiuk
Co-administration of polyphosphazenes with CpG oligodeoxynucleotides strongly enhances immune responses in mice immunized with Hepatitis B virus surface antigen.
Vaccine 2008;26(22):2680-8.
2008: Jae Ku Oem; Candice Jackel-Cram; Yi-Ping Li; Yan Zhou; Jin Zhong; Hitoshi Shimano; Lorne A Babiuk; Qiang Liu
Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2.
The Journal of general virology 2008;89(Pt 5):1225-30.
2008: Radhey S Kaushik; Ashley A Begg; H Wilson; Palok Aich; Mitchell S Abrahamsen; Andrew Potter; Lorne A Babiuk; Philip J Griebel
Establishment of fetal bovine intestinal epithelial cell cultures susceptible to bovine rotavirus infection.
Journal of virological methods 2008;148(1-2):182-96.
2008: Rong Liang; Jan V van den Hurk; A Landi; Z Lawman; Dirk Deregt; H Townsend; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
DNA prime protein boost strategies protect cattle from bovine viral diarrhea virus type 2 challenge.
The Journal of general virology 2008;89(Pt 2):453-66.
2008: Xin-Ming Song; Wayne Connor; Karsten Hokamp; Lorne A Babiuk; Andrew A Potter
Streptococcus pneumoniae early response genes to human lung epithelial cells.
BMC research notes 2008;1():64.
2008: Bhavini A Patel; Susantha Gomis; Arshud Dar; Philip Willson; Lorne A Babiuk; Andrew Potter; George K Mutwiri; Suresh K Tikoo
Oligodeoxynucleotides containing CpG motifs (CpG-ODN) predominantly induce Th1-type immune response in neonatal chicks.
Developmental and comparative immunology 2008;32(9):1041-9.
2008: John W Mapletoft; Mustapha Oumouna; Jennifer Kovacs-Nolan; Laura Latimer; George K Mutwiri; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Intranasal immunization of mice with a formalin-inactivated bovine respiratory syncytial virus vaccine co-formulated with CpG oligodeoxynucleotides and polyphosphazenes results in enhanced protection.
The Journal of general virology 2008;89(Pt 1):250-60.
2008: Jae Ku Oem; C Jackel-Cram; Y-P Li; Hye Na Kang; Yan Zhou; Lorne A Babiuk; Qiang Liu
Hepatitis C virus non-structural protein-2 activates CXCL-8 transcription through NF-kappaB.
Archives of virology 2008;153(2):293-301.
2007: Cemaine H Tsang; Kuldip Mirakhur; Lorne A Babiuk; Philip J Griebel
Oral DNA immunization in the second trimester fetal lamb and secondary immune responses in the neonate.
Vaccine 2007;25(50):8469-79.
2007: Volker Gerdts; Sylvia van Drunen Littel-van den Hurk; Philip J Griebel; Lorne A Babiuk
Use of animal models in the development of human vaccines.
Future microbiology 2007;2(6):667-75.
2007: Yeun-Kyung Shin; Yang Li; Qiang Liu; Deborah H Anderson; Lorne A Babiuk; Yan Zhou
SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation.
Journal of virology 2007;81(23):12730-9.
2007: Palok Aich; H Wilson; Radhey S Kaushik; Andy A Potter; Lorne A Babiuk; Philip J Griebel
Comparative analysis of innate immune responses following infection of newborn calves with bovine rotavirus and bovine coronavirus.
The Journal of general virology 2007;88(Pt 10):2749-61.
2007: Alexander N Zakhartchouk; Sathiyanarayanan Viswanathan; Igor Moshynskyy; Martin Petric; Lorne A Babiuk
Optimization of a DNA vaccine against SARS.
DNA and cell biology 2007;26(10):721-6.
2007: Abdolamir Landi; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
High transfection efficiency, gene expression, and viability of monocyte-derived human dendritic cells after nonviral gene transfer.
Journal of leukocyte biology 2007;82(4):849-60.
2007: Jae Ku Oem; Zhonghua Xiang; Yan Zhou; Lorne A Babiuk; Qiang Liu
Utilization of RNA polymerase I promoter and terminator sequences to develop a DNA transfection system for the study of hepatitis C virus internal ribosomal entry site-dependent translation.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2007;40(1):55-9.
2007: Rong Liang; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Compatibility of plasmids encoding bovine viral diarrhea virus type 1 and type 2 E2 in a single DNA vaccine formulation.
Vaccine 2007;25(32):5994-6006.
2007: Cemaine Tsang; Shawn Babiuk; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; Philip J Griebel
A single DNA immunization in combination with electroporation prolongs the primary immune response and maintains immune memory for six months.
Vaccine 2007;25(30):5485-94.
2007: Igor Moshynskyy; Sathiyanarayanan Viswanathan; Natalia Vasilenko; Vladislav Lobanov; Martin Petric; Lorne A Babiuk; Alexander N Zakhartchouk
Intracellular localization of the SARS coronavirus protein 9b: evidence of active export from the nucleus.
Virus research 2007;127(1):116-21.
2007: Candice Jackel-Cram; Lorne A Babiuk; Qiang Liu
Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: genotype-3a core has a stronger effect than genotype-1b core.
Journal of hepatology 2007;46(6):999-1008.
2007: Jason Kindrachuk; Jean E Potter; Robert Brownlie; Andrew Ficzycz; Philip J Griebel; Neeloffer Mookherjee; George K Mutwiri; Lorne A Babiuk; Scott Napper
Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9.
The Journal of biological chemistry 2007;282(19):13944-53.
2007: Shawn Babiuk; Cemaine Tsang; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; Philip J Griebel
A single HBsAg DNA vaccination in combination with electroporation elicits long-term antibody responses in sheep.
Bioelectrochemistry (Amsterdam, Netherlands) 2007;70(2):269-74.
2007: George K Mutwiri; Volker Gerdts; M Lopez; Lorne A Babiuk
Innate immunity and new adjuvants.
Revue scientifique et technique (International Office of Epizootics) 2007;26(1):147-56.
2007: Susantha Gomis; Lorne A Babiuk; Brenda Allan; Philip Willson; Edwin Waters; Rolf Hecker; Andrew Potter
Protection of chickens against a lethal challenge of Escherichia coli by a vaccine containing CpG oligodeoxynucleotides as an adjuvant.
Avian diseases 2007;51(1):78-83.
2007: Yeun-Kyung Shin; Qiang Liu; Suresh Kumar Tikoo; Lorne A Babiuk; Yan Zhou
Effect of the phosphatidylinositol 3-kinase/Akt pathway on influenza A virus propagation.
The Journal of general virology 2007;88(Pt 3):942-50.
2007: Hong Yu; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Immunity and protection by adoptive transfer of dendritic cells transfected with hepatitis C NS3/4A mRNA.
Vaccine 2007;25(10):1701-11.
2007: Anil K Nichani; M Arshud Dar; Arthur M Krieg; Kuldip Mirakhur; Radhey S Kaushik; Philip J Griebel; Anju Manuja; Hugh G G Townsend; Lorne A Babiuk; George K Mutwiri
Systemic innate immune responses following intrapulmonary delivery of CpG oligodeoxynucleotides in sheep.
Veterinary immunology and immunopathology 2007;115(3-4):357-68.
2007: George K Mutwiri; Ponn Benjamin; Henry Soita; Hugh G G Townsend; Richard Yost; Bryan Roberts; Alexander Andrianov; Lorne A Babiuk
Poly[di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP) is a potent enhancer of mixed Th1/Th2 immune responses in mice immunized with influenza virus antigens.
Vaccine 2007;25(7):1204-13.
2007: Jayaum S Booth; Anil K Nichani; Ponn Benjamin; Arshud Dar; Arthur M Krieg; Lorne A Babiuk; George K Mutwiri
Innate immune responses induced by classes of CpG oligodeoxynucleotides in ovine lymph node and blood mononuclear cells.
Veterinary immunology and immunopathology 2007;115(1-2):24-34.
2007: Alexander N Zakhartchouk; Chetna Sharon; Malathy Satkunarajah; Thierry Auperin; Sathiyanarayanan Viswanathan; George K Mutwiri; Martin Petric; Raymond H See; Robert brunham; B Brett Finlay; Cheryl Cameron; David J Kelvin; Alan Cochrane; James M Rini; Lorne A Babiuk
Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: implications for a subunit vaccine.
Vaccine 2007;25(1):136-43.
2007: Palok Aich; Shakiba Jalal; Carly Czuba; Gabrielle Schatte; Katie Herzog; Douglas J H Olson; Andrew R S Ross; Andy A Potter; Lorne A Babiuk; Philip J Griebel
Comparative approaches to the investigation of responses to stress and viral infection in cattle.
Omics : a journal of integrative biology 2007;11(4):413-34.
2007: Zhijie Chang; Lorne A Babiuk; Jim Hu
Therapeutic and prophylactic potential of small interfering RNAs against severe acute respiratory syndrome: progress to date.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2007;21(1):9-15.
2007: Yeun-Kyung Shin; Qiang Liu; Suresh Kumar Tikoo; Lorne A Babiuk; Yan Zhou
Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K.
The Journal of general virology 2007;88(Pt 1):13-8.
2007: Xiaoxin Li; Lorne A Babiuk; Suresh Kumar Tikoo
Transcription mapping and characterization of proteins produced from early region 4 of porcine adenovirus type 3.
Archives of virology 2007;152(3):495-505.
2006: Neeloffer Mookherjee; H Wilson; Silvana Doria; Yurij Popowych; Reza Falsafi; Jie Jessie Yu; Yuexin Li; Sarah Veatch; Fiona M Roche; Kelly L Brown; Fiona S L Brinkman; Karsten Hokamp; Andrew Potter; Lorne A Babiuk; Philip J Griebel; Robert E W Hancock
Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide.
Journal of leukocyte biology 2006;80(6):1563-74.
2006: Yi-Ping Li; Hye Na Kang; Lorne A Babiuk; Qiang Liu
Elicitation of strong immune responses by a DNA vaccine expressing a secreted form of hepatitis C virus envelope protein E2 in murine and porcine animal models.
World journal of gastroenterology : WJG 2006;12(44):7126-35.
2006: A M Lopez; Rolf Hecker; George K Mutwiri; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; Hugh G G Townsend
Formulation with CpG ODN enhances antibody responses to an equine influenza virus vaccine.
Veterinary immunology and immunopathology 2006;114(1-2):103-10.
2006: Rong Liang; Jan V van den Hurk; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Priming with DNA encoding E2 and boosting with E2 protein formulated with CpG oligodeoxynucleotides induces strong immune responses and protection from Bovine viral diarrhea virus in cattle.
The Journal of general virology 2006;87(Pt 10):2971-82.
2006: John W Mapletoft; Mustapha Oumouna; Hugh G G Townsend; Susantha Gomis; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Formulation with CpG oligodeoxynucleotides increases cellular immunity and protection induced by vaccination of calves with formalin-inactivated bovine respiratory syncytial virus.
Virology 2006;353(2):316-23.
2006: Tyler A Whale; H Wilson; Suresh Kumar Tikoo; Lorne A Babiuk; Philip J Griebel
Pivotal Advance: passively acquired membrane proteins alter the functional capacity of bovine polymorphonuclear cells.
Journal of leukocyte biology 2006;80(3):481-91.
2006: Y Huang; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
The cell-mediated immune response induced by plasmid encoding bovine herpesvirus 1 glycoprotein B is enhanced by plasmid encoding IL-12 when delivered intramuscularly or by gene gun, but not after intradermal injection.
Vaccine 2006;24(25):5349-59.
2006: Tyler A Whale; Terry K Beskorwayne; Lorne A Babiuk; Philip J Griebel
Bovine polymorphonuclear cells passively acquire membrane lipids and integral membrane proteins from apoptotic and necrotic cells.
Journal of leukocyte biology 2006;79(6):1226-33.
2006: Chunfu Zheng; Christiane Juhls; Detlef Oswald; Florian Sack; Ines Westfehling; Burghardt Wittig; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Effect of different nuclear localization sequences on the immune responses induced by a MIDGE vector encoding bovine herpesvirus-1 glycoprotein D.
Vaccine 2006;24(21):4625-9.
2006: H Wilson; Arshud Dar; Scott Napper; A Marianela Lopez; Lorne A Babiuk; George K Mutwiri
Immune mechanisms and therapeutic potential of CpG oligodeoxynucleotides.
International reviews of immunology 2006;25(3-4):183-213.
2006: Shokrollah Elahi; Rachelle M Buchanan; Lorne A Babiuk; Volker Gerdts
Maternal immunity provides protection against pertussis in newborn piglets.
Infection and immunity 2006;74(5):2619-27.
2006: Volker Gerdts; George K Mutwiri; Suresh Kumar Tikoo; Lorne A Babiuk
Mucosal delivery of vaccines in domestic animals.
Veterinary research 2006;37(3):487-510.
2006: C F Zheng; Robert Brownlie; D Y Huang; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Intercellular trafficking of the major tegument protein VP22 of bovine herpesvirus-1 and its application to improve a DNA vaccine.
Archives of virology 2006;151(5):985-93.
2006: Valeria L Alcón; Maria E Baca-Estrada; Andrew Potter; Lorne A Babiuk; Praveen Kumar; Marianna Foldvari
Biphasic lipid vesicles as a subcutaneous delivery system for protein antigens and CpG oligonucleotides.
Current drug delivery 2006;3(2):129-35.
2006: Shokrollah Elahi; Rachelle M Buchanan; Sam Attah-Poku; Hugh G G Townsend; Lorne A Babiuk; Volker Gerdts
The host defense peptide beta-defensin 1 confers protection against Bordetella pertussis in newborn piglets.
Infection and immunity 2006;74(4):2338-52.
2006: Rowan Higgs; Paul Cormican; Sarah Cahalane; Brenda Allan; Andrew T Lloyd; Kieran Meade; Tharappel James; David J Lynn; Lorne A Babiuk; Cliona O'Farrelly
Induction of a novel chicken Toll-like receptor following Salmonella enterica serovar Typhimurium infection.
Infection and immunity 2006;74(3):1692-8.
2006: Raymond H See; Alexander N Zakhartchouk; Martin Petric; David J Lawrence; Catherine P Y Mok; Robert Jeffrey Hogan; Thomas Rowe; Lois A Zitzow; Karuna P Karunakaran; Mary M Hitt; Frank L Graham; Ludvik Prevec; James B Mahony; Chetna Sharon; Thierry C Auperin; James M Rini; Aubrey J Tingle; David W Scheifele; Danuta M Skowronski; David M Patrick; Thomas G Voss; Lorne A Babiuk; Jack Gauldie; Rachel L Roper; Robert brunham; B Brett Finlay
Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus.
The Journal of general virology 2006;87(Pt 3):641-50.
2006: Sampathkumar Balamurugan; Scott Napper; Catherine D Carrillo; Philip Willson; Eduardo Taboada; John H E Nash; Andrew A Potter; Lorne A Babiuk; Brenda Allan
Transcriptional and translational expression patterns associated with immobilized growth of Campylobacter jejuni.
Microbiology (Reading, England) 2006;152(Pt 2):567-77.
2006: Sylvia van Drunen Littel-van den Hurk; Shawn Babiuk; Lorne A Babiuk
Needle-free delivery of veterinary DNA vaccines.
Methods in molecular medicine 2006;127():91-105.
2006: Shawn Babiuk; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk
Delivery of DNA vaccines using electroporation.
Methods in molecular medicine 2006;127():73-82.
2006: Anil K Nichani; Angelo Mena; Radhey S Kaushik; George K Mutwiri; Hugh G G Townsend; Rolf Hecker; Arthur M Krieg; Lorne A Babiuk; Philip J Griebel
Stimulation of innate immune responses by CpG oligodeoxynucleotide in newborn lambs can reduce bovine herpesvirus-1 shedding.
Oligonucleotides 2006;16(1):58-67.
2006: Hong Yu; Hui Huang; Jim Xiang; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Dendritic cells pulsed with hepatitis C virus NS3 protein induce immune responses and protection from infection with recombinant vaccinia virus expressing NS3.
The Journal of general virology 2006;87(Pt 1):1-10.
2005: Rong Liang; Jan V van den Hurk; Chunfu Zheng; Hong Yu; Reno Pontarollo; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Immunization with plasmid DNA encoding a truncated, secreted form of the bovine viral diarrhea virus E2 protein elicits strong humoral and cellular immune responses.
Vaccine 2005;23(45):5252-62.
2005: Philip J Griebel; Robert Brownlie; Anju Manuja; Anil K Nichani; Neeloffer Mookherjee; Yurij Popowych; George K Mutwiri; Rolf Hecker; Lorne A Babiuk
Bovine toll-like receptor 9: a comparative analysis of molecular structure, function and expression.
Veterinary immunology and immunopathology 2005;108(1-2):11-6.
2005: Frank H Gaertner; Lorne A Babiuk; Elaine A Van Moorlehem; Terry K Beskorwayne; Stacey L Lee; Robert W Shutter; Janna M Armstrong; Philip J Griebel
Amended recombinant cells (ARCs): an economical and surprisingly effective production and delivery vehicle for recombinant bovine IFN-gamma.
Journal of controlled release : official journal of the Controlled Release Society 2005;107(2):189-202.
2005: George K Mutwiri; Terry L Bowersock; Lorne A Babiuk
Microparticles for oral delivery of vaccines.
Expert opinion on drug delivery 2005;2(5):791-806.
2005: Chunfu Zheng; Robert Brownlie; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Characterization of the nuclear localization and nuclear export signals of bovine herpesvirus 1 VP22.
Journal of virology 2005;79(18):11864-72.
2005: Alexander N Zakhartchouk; Qiang Liu; Martin Petric; Lorne A Babiuk
Augmentation of immune responses to SARS coronavirus by a combination of DNA and whole killed virus vaccines.
Vaccine 2005;23(35):4385-91.
2005: Martin Vordermeier; Reno Pontarollo; Brenda Karvonen; Paul J Cockle; Rolf Hecker; Mahavir Singh; Lorne A Babiuk; R Glyn Hewinson; Sylvia van Drunen Littel-van den Hurk
Synthetic peptide vaccination in cattle: induction of strong cellular immune responses against peptides derived from the Mycobacterium bovis antigen Rv3019c.
Vaccine 2005;23(35):4375-84.
2005: Valeria L Alcón; Maria E Baca-Estrada; M A Vega-López; Philip Willson; Lorne A Babiuk; Praveen Kumar; Marianna Foldvari
Intranasal immunization using biphasic lipid vesicles as delivery systems for OmlA bacterial protein antigen and CpG oligonucleotides adjuvant in a mouse model.
The Journal of pharmacy and pharmacology 2005;57(8):955-62.
2005: Turaya Naas; Masoud Ghorbani; Ikuri Alvarez-Maya; Michael Lapner; Rashmi Kothary; Yves De Repentigny; Susantha Gomes; Lorne A Babiuk; Antonio Giulivi; Catalina Soare; Ali Azizi; Francisco Diaz-Mitoma
Characterization of liver histopathology in a transgenic mouse model expressing genotype 1a hepatitis C virus core and envelope proteins 1 and 2.
The Journal of general virology 2005;86(Pt 8):2185-96.
2005: D Neil Wedlock; Margot A Skinner; Geoffrey W de Lisle; Martin Vordermeier; R Glyn Hewinson; Rolf Hecker; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; Bryce M Buddle
Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and CpG oligodeoxynucleotides induces protection against bovine tuberculosis.
Veterinary immunology and immunopathology 2005;106(1-2):53-63.
2005: Shokrollah Elahi; Robert Brownlie; J Korzeniowski; R Buchanan; B O'Connor; M S Peppler; S A Halperin; S F Lee; Lorne A Babiuk; Volker Gerdts
Infection of newborn piglets with Bordetella pertussis: a new model for pertussis.
Infection and immunity 2005;73(6):3636-45.
2005: D Neil Wedlock; Michel Denis; Margot A Skinner; Jessica Koach; Geoffrey W de Lisle; Martin Vordermeier; R Glyn Hewinson; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; Rolf Hecker; Bryce M Buddle
Vaccination of cattle with a CpG oligodeoxynucleotide-formulated mycobacterial protein vaccine and Mycobacterium bovis BCG induces levels of protection against bovine tuberculosis superior to those induced by vaccination with BCG alone.
Infection and immunity 2005;73(6):3540-6.
2005: Arshud Dar; Shirin Munir; Satya Vishwanathan; Anju Manuja; Philip J Griebel; Suresh Kumar Tikoo; Hugh G G Townsend; Andrew Potter; Vivek Kapur; Lorne A Babiuk
Transcriptional analysis of avian embryonic tissues following infection with avian infectious bronchitis virus.
Virus research 2005;110(1-2):41-55.
2005: H Wilson; Palok Aich; Fiona M Roche; Shakiba Jalal; Paul D Hodgson; Fiona S L Brinkman; Andrew Potter; Lorne A Babiuk; Philip J Griebel
Molecular analyses of disease pathogenesis: application of bovine microarrays.
Veterinary immunology and immunopathology 2005;105(3-4):277-87.
2005: Tieshi Li; Yan Zhang; L Fu; C Yu; Xuemei Li; Yanda Li; Xuegong Zhang; Z Rong; Yinyin Wang; Hongxiu Ning; R Liang; Wei Chen; Lorne A Babiuk; Zhijie Chang
siRNA targeting the leader sequence of SARS-CoV inhibits virus replication.
Gene therapy 2005;12(9):751-61.
2005: Y Huang; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Immunization with a bovine herpesvirus 1 glycoprotein B DNA vaccine induces cytotoxic T-lymphocyte responses in mice and cattle.
The Journal of general virology 2005;86(Pt 4):887-98.
2005: Mustapha Oumouna; John W Mapletoft; Brenda Karvonen; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Formulation with CpG oligodeoxynucleotides prevents induction of pulmonary immunopathology following priming with formalin-inactivated or commercial killed bovine respiratory syncytial virus vaccine.
Journal of virology 2005;79(4):2024-32.
2005: Chunfu Zheng; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Bovine herpesvirus 1 VP22 enhances the efficacy of a DNA vaccine in cattle.
Journal of virology 2005;79(3):1948-53.
2005: Valeria Alcon; Maria E Baca-Estrada; Marco Vega-Lopez; Philip Willson; Lorne A Babiuk; Praveen Kumar; Rolf Hecker; Marianna Foldvari
Mucosal delivery of bacterial antigens and CpG oligonucleotides formulated in biphasic lipid vesicles in pigs.
The AAPS journal 2005;7(3):E566-71.
2005: Danuta M Skowronski; Caroline R Astell; Robert brunham; Donald E Low; Martin Petric; Rachel L Roper; Pierre J Talbot; Theresa Tam; Lorne A Babiuk
Severe acute respiratory syndrome (SARS): a year in review.
Annual review of medicine 2005;56():357-81.
2005: Alexander N Zakhartchouk; Sathiyanarayanan Viswanathan; James B Mahony; Jack Gauldie; Lorne A Babiuk
Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice.
The Journal of general virology 2005;86(Pt 1):211-5.
2004: Susantha Gomis; Lorne A Babiuk; Brenda Allan; Philip Willson; Edwin Waters; Neil Ambrose; Rolf Hecker; Andrew Potter
Protection of neonatal chicks against a lethal challenge of Escherichia coli using DNA containing cytosine-phosphodiester-guanine motifs.
Avian diseases 2004;48(4):813-22.
2004: Daniel Mariano Pérez-Filgueira; Marina Mozgovoj; Andrés Wigdorovitz; maria jose dus santos; Viviana Parreño; Karina Trono; F M Fernandez; Consuelo Carrillo; Lorne A Babiuk; T Jack Morris; Manuel V Borca
Passive protection to bovine rotavirus (BRV) infection induced by a BRV VP8* produced in plants using a TMV-based vector.
Archives of virology 2004;149(12):2337-48.
2004: Shawn Babiuk; Neeloffer Mookherjee; Reno Pontarollo; Philip J Griebel; Sylvia van Drunen Littel-van den Hurk; Rolf Hecker; Lorne A Babiuk
TLR9-/- and TLR9+/+ mice display similar immune responses to a DNA vaccine.
Immunology 2004;113(1):114-20.
2004: Xiaoxin Li; Lorne A Babiuk; Suresh Kumar Tikoo
Analysis of early region 4 of porcine adenovirus type 3.
Virus research 2004;104(2):181-90.
2004: Andrés Wigdorovitz; Marina Mozgovoj; María J Dus Santos; Viviana Parreño; Cristina Gómez; Daniel Mariano Pérez-Filgueira; Karina Trono; Raúl D Ríos; Pascual M Franzone; Fernando Fernández; Consuelo Carrillo; Lorne A Babiuk; José M Escribano; Manuel V Borca
Protective lactogenic immunity conferred by an edible peptide vaccine to bovine rotavirus produced in transgenic plants.
The Journal of general virology 2004;85(Pt 7):1825-32.
2004: Fiona M Roche; Karsten Hokamp; Michael Acab; Lorne A Babiuk; Robert E W Hancock; Fiona S L Brinkman
ProbeLynx: a tool for updating the association of microarray probes to genes.
Nucleic acids research 2004;32(Web Server issue):W471-4.
2004: Karsten Hokamp; Fiona M Roche; Michael Acab; Marc-Etienne Rousseau; Byron Kuo; David Goode; Dana Aeschliman; Jenny Bryan; Lorne A Babiuk; Robert E W Hancock; Fiona S L Brinkman
ArrayPipe: a flexible processing pipeline for microarray data.
Nucleic acids research 2004;32(Web Server issue):W457-9.
2004: Chunfu Zheng; Robert Brownlie; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Characterization of nuclear localization and export signals of the major tegument protein VP8 of bovine herpesvirus-1.
Virology 2004;324(2):327-39.
2004: Sylvia van Drunen Littel-van den Hurk; Shawn Babiuk; Lorne A Babiuk
Strategies for improved formulation and delivery of DNA vaccines to veterinary target species.
Immunological reviews 2004;199():113-25.
2004: Hong Yu; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Priming with CpG-enriched plasmid and boosting with protein formulated with CpG oligodeoxynucleotides and Quil A induces strong cellular and humoral immune responses to hepatitis C virus NS3.
The Journal of general virology 2004;85(Pt 6):1533-43.
2004: Sharmila Manoj; Philip J Griebel; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Modulation of immune responses to bovine herpesvirus-1 in cattle by immunization with a DNA vaccine encoding glycoprotein D as a fusion protein with bovine CD154.
Immunology 2004;112(2):328-38.
2004: George K Mutwiri; Anil K Nichani; Shawn Babiuk; Lorne A Babiuk
Strategies for enhancing the immunostimulatory effects of CpG oligodeoxynucleotides.
Journal of controlled release : official journal of the Controlled Release Society 2004;97(1):1-17.
2004: Vikas Kulshreshtha; Lorne A Babiuk; Suresh Kumar Tikoo
Role of bovine adenovirus-3 33K protein in viral replication.
Virology 2004;323(1):59-69.
2004: Shawn Babiuk; Maria E Baca-Estrada; Marianna Foldvari; Dorothy M Middleton; Dietmar Rabussay; Georg Widera; Lorne A Babiuk
Increased gene expression and inflammatory cell infiltration caused by electroporation are both important for improving the efficacy of DNA vaccines.
Journal of biotechnology 2004;110(1):1-10.
2004: Catherine D Carrillo; Eduardo Taboada; John H E Nash; Patricia Lanthier; John Kelly; Peter C. Y. Lau; Rachel Verhulp; Oksana L Mykytczuk; Jonathan Sy; Wendy A Findlay; Kingsley Amoako; Susantha Gomis; Philip Willson; John W Austin; Andrew Potter; Lorne A Babiuk; Brenda Allan; Christine M Szymanski
Genome-wide expression analyses of Campylobacter jejuni NCTC11168 reveals coordinate regulation of motility and virulence by flhA.
The Journal of biological chemistry 2004;279(19):20327-38.
2004: Volker Gerdts; Cemaine Tsang; Philip J Griebel; Lorne A Babiuk
DNA vaccination in utero: a new approach to induce protective immunity in the newborn.
Vaccine 2004;22(13-14):1717-27.
2004: Anil K Nichani; Angelo Mena; Yurij Popowych; Donna Dent; Hugh G G Townsend; George K Mutwiri; Rolf Hecker; Lorne A Babiuk; Philip J Griebel
In vivo immunostimulatory effects of CpG oligodeoxynucleotide in cattle and sheep.
Veterinary immunology and immunopathology 2004;98(1-2):17-29.
2004: Yuanjiang Zhang; Tieshi Li; Ling Fu; Changming Yu; Yinghua Li; Xialian Xu; Yinyin Wang; Hongxiu Ning; Shuping Zhang; Wei Chen; Lorne A Babiuk; Zhijie Chang
Silencing SARS-CoV Spike protein expression in cultured cells by RNA interference.
FEBS letters 2004;560(1-3):141-6.
2004: Shawn Babiuk; Maria E Baca-Estrada; Dorothy M Middleton; Rolf Hecker; Lorne A Babiuk; Marianna Foldvari
Biphasic lipid vesicles (Biphasix) enhance the adjuvanticity of CpG oligonucleotides following systemic and mucosal administration.
Current drug delivery 2004;1(1):9-15.
2004: Sharmila Manoj; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Approaches to enhance the efficacy of DNA vaccines.
Critical reviews in clinical laboratory sciences 2004;41(1):1-39.
2004: Anil K Nichani; Radhey S Kaushik; Angelo Mena; Yurij Popowych; Donna Dent; Hugh G G Townsend; George K Mutwiri; Rolf Hecker; Lorne A Babiuk; Philip J Griebel
CpG oligodeoxynucleotide induction of antiviral effector molecules in sheep.
Cellular immunology 2004;227(1):24-37.
2004: Shawn Babiuk; Danuta M Skowronski; Gaston De Serres; Kent T Hayglass; Robert brunham; Lorne A Babiuk
Aggregate content influences the Th1/Th2 immune response to influenza vaccine: evidence from a mouse model.
Journal of medical virology 2004;72(1):138-42.
2003: Shawn Babiuk; Maria E Baca-Estrada; Marianna Foldvari; Lawrence Baizer; Richard Stout; Michael Storms; Dietmar Rabussay; Georg Widera; Lorne A Babiuk
Needle-free topical electroporation improves gene expression from plasmids administered in porcine skin.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(6):992-8.
2003: Igor Moshynskyy; Min Jiang; Michael C Fontaine; Jose Perez-Casal; Lorne A Babiuk; Andrew A Potter
Characterization of a bovine lactoferrin binding protein of Streptococcus uberis.
Microbial pathogenesis 2003;35(5):203-15.
2003: Angelo Mena; Anil K Nichani; Yurij Popowych; Dale L Godson; Donna Dent; Hugh G G Townsend; George K Mutwiri; Rolf Hecker; Lorne A Babiuk; Philip J Griebel
Innate immune responses induced by CpG oligodeoxyribonucleotide stimulation of ovine blood mononuclear cells.
Immunology 2003;110(2):250-7.
2003: Xenia P Ioannou; Susantha Gomis; Rolf Hecker; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Safety and efficacy of CpG-containing oligodeoxynucleotides as immunological adjuvants in rabbits.
Vaccine 2003;21(27-30):4368-72.
2003: Sharmila Manoj; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Immunization with a dicistronic plasmid expressing a truncated form of bovine herpesvirus-1 glycoprotein D and the amino-terminal subunit of glycoprotein B results in reduced gB-specific immune responses.
Virology 2003;313(1):296-307.
2003: Lorne A Babiuk; Susantha Gomis; Rolf Hecker
Molecular approaches to disease control.
Poultry science 2003;82(6):870-5.
2003: Valeria L Alcón; Marianna Foldvari; Marlene Snider; Philip Willson; Susantha Gomis; Rolf Hecker; Lorne A Babiuk; Maria E Baca-Estrada
Induction of protective immunity in pigs after immunisation with CpG oligodeoxynucleotides formulated in a lipid-based delivery system (Biphasix).
Vaccine 2003;21(17-18):1811-4.
2003: Susantha Gomis; Lorne A Babiuk; Dale L Godson; Brenda Allan; Tannis Thrush; Hugh G G Townsend; Philip Willson; Edwin Waters; Rolf Hecker; Andrew Potter
Protection of chickens against Escherichia coli infections by DNA containing CpG motifs.
Infection and immunity 2003;71(2):857-63.
2003: George K Mutwiri; Reno Pontarollo; Shawn Babiuk; Philip J Griebel; Sylvia van Drunen Littel-van den Hurk; Angelo Mena; Cemaine Tsang; V Alcon; Anil K Nichani; Xenia P Ioannou; Susantha Gomis; Hugh G G Townsend; Rolf Hecker; Andrew Potter; Lorne A Babiuk
Biological activity of immunostimulatory CpG DNA motifs in domestic animals.
Veterinary immunology and immunopathology 2003;91(2):89-103.
2003: Lorne A Babiuk; Reno Pontarollo; Shawn Babiuk; BI Loehr; Sylvia van Drunen Littel-van den Hurk
Induction of immune responses by DNA vaccines in large animals.
Vaccine 2003;21(7-8):649-58.
2003: Sharmila Manoj; Philip J Griebel; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Targeting with bovine CD154 enhances humoral immune responses induced by a DNA vaccine in sheep.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):989-96.
2003: Angelo Mena; Anil K Nichani; Yurij Popowych; Xenia P Ioannou; Dale L Godson; George K Mutwiri; Rolf Hecker; Lorne A Babiuk; Philip J Griebel
Bovine and ovine blood mononuclear leukocytes differ markedly in innate immune responses induced by Class A and Class B CpG-oligodeoxynucleotide.
Oligonucleotides 2003;13(4):245-59.
2003: Xenia P Ioannou; Philip J Griebel; Angelo Mena; Susantha Gomis; Dale L Godson; George K Mutwiri; Rolf Hecker; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Safety of CpG oligodeoxynucleotides in veterinary species.
Antisense & nucleic acid drug development 2003;13(3):157-67.
2002: B Kim; Terry L Bowersock; Philip J Griebel; Kidane Argaw; Lorne A Babiuk; Margaret Sanchez; Samuel Attah-Poku; Radhey S Kaushik; George K Mutwiri
Mucosal immune responses following oral immunization with rotavirus antigens encapsulated in alginate microspheres.
Journal of controlled release : official journal of the Controlled Release Society 2002;85(1-3):191-202.
2002: Stacy L Stocki; Lorne A Babiuk; Neil A Rawlyk; Andrew A Potter; Brenda Allan
Identification of genomic differences between Escherichia coli strains pathogenic for poultry and E. coli K-12 MG1655 using suppression subtractive hybridization analysis.
Microbial pathogenesis 2002;33(6):289-98.
2002: Reno Pontarollo; Lorne A Babiuk; Rolf Hecker; Sylvia van Drunen Littel-van den Hurk
Augmentation of cellular immune responses to bovine herpesvirus-1 glycoprotein D by vaccination with CpG-enhanced plasmid vectors.
The Journal of general virology 2002;83(Pt 12):2973-81.
2002: Xenia P Ioannou; Susantha Gomis; Brenda Karvonen; Rolf Hecker; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
CpG-containing oligodeoxynucleotides, in combination with conventional adjuvants, enhance the magnitude and change the bias of the immune responses to a herpesvirus glycoprotein.
Vaccine 2002;21(1-2):127-37.
2002: Lorne A Babiuk
Vaccination: a management tool in veterinary medicine.
Veterinary journal (London, England : 1997) 2002;164(3):188-201.
2002: Qiang Liu; Li Wang; Philip Willson; Brendan O'Connor; Julia Keenliside; Manuel Chirino-Trejo; Ronald Meléndez; Lorne A Babiuk
Seroprevalence of porcine circovirus type 2 in swine populations in Canada and Costa Rica.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 2002;66(4):225-31.
2002: Shawn Babiuk; Maria E Baca-Estrada; Marianna Foldvari; Michael Storms; Dietmar Rabussay; Georg Widera; Lorne A Babiuk
Electroporation improves the efficacy of DNA vaccines in large animals.
Vaccine 2002;20(27-28):3399-3408.
2002: George K Mutwiri; Terry L Bowersock; Kidane Argaw; Margaret Sanchez; Volker Gerdts; Lorne A Babiuk; Philip J Griebel
Induction of mucosal immune responses following enteric immunization with antigen delivered in alginate microspheres.
Veterinary immunology and immunopathology 2002;87(3-4):269-76.
2002: Maria E Baca-Estrada; Catherine Ewen; Donna Mahony; Lorne A Babiuk; Darryl Wilkie; Marianna Foldvari
The haemopoietic growth factor, Flt3L, alters the immune response induced by transcutaneous immunization.
Immunology 2002;107(1):69-76.
2002: Xenia P Ioannou; Philip J Griebel; Rolf Hecker; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
The immunogenicity and protective efficacy of bovine herpesvirus 1 glycoprotein D plus Emulsigen are increased by formulation with CpG oligodeoxynucleotides.
Journal of virology 2002;76(18):9002-10.
2002: Lorne A Babiuk
3rd World Congress on Vaccines and Immunisation. June 4-9 2002, Opatija Adriatic Riviera, Croatia.
Expert opinion on biological therapy 2002;2(6):665-9.
2002: R Rankin; Reno Pontarollo; Susantha Gomis; Brenda Karvonen; Philip Willson; BI Loehr; Dale L Godson; Lorne A Babiuk; Rolf Hecker; Sylvia van Drunen Littel-van den Hurk
CpG-containing oligodeoxynucleotides augment and switch the immune responses of cattle to bovine herpesvirus-1 glycoprotein D.
Vaccine 2002;20(23-24):3014-22.
2002: Angelo Mena; Xenia P Ioannou; Andrew G Van Kessel; Sylvia Van Drunen Little-Van Den Hurk; Yurij Popowych; Lorne A Babiuk; Dale L Godson
Th1/Th2 biasing effects of vaccination in cattle as determined by real-time PCR.
Journal of immunological methods 2002;263(1-2):11-21.
2002: Volker Gerdts; Marlene Snider; Robert Brownlie; Lorne A Babiuk; Philip J Griebel
Oral DNA vaccination in utero induces mucosal immunity and immune memory in the neonate.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1877-85.
2002: Lorne A Babiuk; Shawn Babiuk; Maria E Baca-Estrada
Novel vaccine strategies.
Advances in virus research 2002;58():29-80.
2002: Reno Pontarollo; R Rankin; Lorne A Babiuk; Dale L Godson; Philip J Griebel; Rolf Hecker; Arthur M Krieg; Sylvia van Drunen Littel-van den Hurk
Monocytes are required for optimum in vitro stimulation of bovine peripheral blood mononuclear cells by non-methylated CpG motifs.
Veterinary immunology and immunopathology 2002;84(1-2):43-59.
2001: Richard R E Uwiera; Volker Gerdts; Reno Pontarollo; Lorne A Babiuk; Dorothy M Middleton; Philip J Griebel
Plasmid DNA induces increased lymphocyte trafficking: a specific role for CpG motifs.
Cellular immunology 2001;214(2):155-64.
2001: BI Loehr; Reno Pontarollo; R Rankin; Laura Latimer; Philip Willson; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Priming by DNA immunization augments T-cell responses induced by modified live bovine herpesvirus vaccine.
The Journal of general virology 2001;82(Pt 12):3035-43.
2001: Mohit K Baxi; J Robertson; Lorne A Babiuk; Suresh Kumar Tikoo
Mutational analysis of early region 4 of bovine adenovirus type 3.
Virology 2001;290(1):153-63.
2001: Andrew A Potter; Lorne A Babiuk
New approaches for antigen discovery, production and delivery: vaccines for veterinary and human use.
Current drug targets. Infectious disorders 2001;1(3):249-62.
2001: S Suradhat; RP Braun; PJ Lewis; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk; Philip J Griebel; Maria E Baca-Estrada
Fusion of C3d molecule with bovine rotavirus VP7 or bovine herpesvirus type 1 glycoprotein D inhibits immune responses following DNA immunization.
Veterinary immunology and immunopathology 2001;83(1-2):79-92.
2001: BI Loehr; R Rankin; Reno Pontarollo; T King; Philip Willson; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Suppository-mediated DNA immunization induces mucosal immunity against bovine herpesvirus-1 in cattle.
Virology 2001;289(2):327-33.
2001: R Rankin; Reno Pontarollo; Xenia P Ioannou; Arthur M Krieg; Rolf Hecker; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
CpG motif identification for veterinary and laboratory species demonstrates that sequence recognition is highly conserved.
Antisense & nucleic acid drug development 2001;11(5):333-40.
2001: Volker Gerdts; Richard R E Uwiera; George K Mutwiri; D J Wilson; Terry L Bowersock; Kidane Argaw; Lorne A Babiuk; Philip J Griebel
Multiple intestinal 'loops' provide an in vivo model to analyse multiple mucosal immune responses.
Journal of immunological methods 2001;256(1-2):19-33.
2001: Yan Zhou; P Seshidhar Reddy; Lorne A Babiuk; Suresh Kumar Tikoo
Bovine adenovirus type 3 E1B(small) protein is essential for growth in bovine fibroblast cells.
Virology 2001;288(2):264-74.
2001: Qiang Liu; Suresh Kumar Tikoo; Lorne A Babiuk
Nuclear localization of the ORF2 protein encoded by porcine circovirus type 2.
Virology 2001;285(1):91-9.
2001: Sylvia van Drunen Littel-van den Hurk; D Myers; P A Doig; Brenda Karvonen; M Habermehl; Lorne A Babiuk; M Jelinski; J Van Donkersgoed; K Schlesinger; Carol L Rinehart
Identification of a mutant bovine herpesvirus-1 (BHV-1) in post-arrival outbreaks of IBR in feedlot calves and protection with conventional vaccination.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 2001;65(2):81-8.
2001: Sylvia van Drunen Littel-van den Hurk; BI Loehr; Lorne A Babiuk
Immunization of livestock with DNA vaccines: current studies and future prospects.
Vaccine 2001;19(17-19):2474-9.
2001: Richard R E Uwiera; R Rankin; Gregg P Adams; Reno Pontarollo; Sylvia van Drunen Littel-van den Hurk; Dorothy M Middleton; Lorne A Babiuk; Philip J Griebel
Effects of intradermally administered plasmid deoxyribonucleic acid on ovine popliteal lymph node morphology.
The Anatomical record 2001;262(2):186-92.
2001: Qiang Liu; Philip Willson; S Attoh-Poku; Lorne A Babiuk
Bacterial expression of an immunologically reactive PCV2 ORF2 fusion protein.
Protein expression and purification 2001;21(1):115-20.
2001: Alexander N Zakhartchouk; Dale L Godson; Lorne A Babiuk; Suresh Kumar Tikoo
121R protein from the E3 region of bovine adenovirus-3 inhibits cytolysis of mouse cells by human tumor necrosis factor.
Intervirology 2001;44(1):29-35.
2000: Mohit K Baxi; Dirk Deregt; J Robertson; Lorne A Babiuk; T Schlapp; Suresh Kumar Tikoo
Recombinant bovine adenovirus type 3 expressing bovine viral diarrhea virus glycoprotein E2 induces an immune response in cotton rats.
Virology 2000;278(1):234-43.
2000: D Tatlow; R Brownlie; Lorne A Babiuk; Philip J Griebel
Differential display analysis of gene expression during the induction of mucosal immunity.
Immunogenetics 2000;52(1-2):73-80.
2000: Camilo Raggo; M Habermehl; Lorne A Babiuk; Philip J Griebel
The in vivo effects of recombinant bovine herpesvirus-1 expressing bovine interferon-gamma.
The Journal of general virology 2000;81(Pt 11):2665-73.
2000: P Seshidhar Reddy; Neeraja Idamakanti; C Pyne; Alexander N Zakhartchouk; Dale L Godson; Z Papp; Maria E Baca-Estrada; Lorne A Babiuk; George K Mutwiri; Suresh Kumar Tikoo
The immunogenicity and efficacy of replication-defective and replication-competent bovine adenovirus-3 expressing bovine herpesvirus-1 glycoprotein gD in cattle.
Veterinary immunology and immunopathology 2000;76(3-4):257-68.
2000: Lorne A Babiuk; Suresh Kumar Tikoo
Adenoviruses as vectors for delivering vaccines to mucosal surfaces.
Journal of biotechnology 2000;83(1-2):105-13.
2000: Maria E Baca-Estrada; Marianna Foldvari; Shawn Babiuk; Lorne A Babiuk
Vaccine delivery: lipid-based delivery systems.
Journal of biotechnology 2000;83(1-2):91-104.
2000: Sylvia van Drunen Littel-van den Hurk; Volker Gerdts; BI Loehr; Reno Pontarollo; R Rankin; Richard R E Uwiera; Lorne A Babiuk
Recent advances in the use of DNA vaccines for the treatment of diseases of farmed animals.
Advanced drug delivery reviews 2000;43(1):13-28.
2000: P Seshidhar Reddy; Neeraja Idamakanti; L N Zakhartchouk; Lorne A Babiuk; M Mehtali; Suresh Kumar Tikoo
Optimization of bovine coronavirus hemagglutinin-estrase glycoprotein expression in E3 deleted bovine adenovirus-3.
Virus research 2000;70(1-2):65-73.
2000: Qiang Liu; L Wang; Philip Willson; Lorne A Babiuk
Quantitative, competitive PCR analysis of porcine circovirus DNA in serum from pigs with postweaning multisystemic wasting syndrome.
Journal of clinical microbiology 2000;38(9):3474-7.
2000: Lorne A Babiuk; Shawn Babiuk; BI Loehr
Nucleic acid vaccines: research tool or commercial reality.
Veterinary immunology and immunopathology 2000;76(1-2):1-23.
2000: Volker Gerdts; Lorne A Babiuk; Philip J Griebel
Fetal immunization by a DNA vaccine delivered into the oral cavity.
Nature medicine 2000;6(8):929-32.
2000: BI Loehr; Philip Willson; Lorne A Babiuk
Gene gun-mediated DNA immunization primes development of mucosal immunity against bovine herpesvirus 1 in cattle.
Journal of virology 2000;74(13):6077-86.
2000: Shawn Babiuk; Maria E Baca-Estrada; Lorne A Babiuk; Catherine Ewen; Marianna Foldvari
Cutaneous vaccination: the skin as an immunologically active tissue and the challenge of antigen delivery.
Journal of controlled release : official journal of the Controlled Release Society 2000;66(2-3):199-214.
2000: Maria E Baca-Estrada; Marianna Foldvari; Marlene Snider; K K Harding; B B Kournikakis; Lorne A Babiuk; P P Griebel
Intranasal immunization with liposome-formulated Yersinia pestis vaccine enhances mucosal immune responses.
Vaccine 2000;18(21):2203-11.
2000: Maria E Baca-Estrada; Marianna Foldvari; Catherine Ewen; Ildiko Badea; Lorne A Babiuk
Effects of IL-12 on immune responses induced by transcutaneous immunization with antigens formulated in a novel lipid-based biphasic delivery system.
Vaccine 2000;18(17):1847-54.
2000: Sylvia van Drunen Littel-van den Hurk; R P Braun; Lorne A Babiuk
Veterinary DNA vaccines.
Methods in molecular medicine 2000;29():79-94.
2000: Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk; BI Loehr; Richard R E Uwiera
Veterinary applications of DNA vaccines.
Developments in biologicals 2000;104():73-81.
1999: Lorne A Babiuk; Shawn Babiuk
Immunization of animals: from DNA to the dinner plate.
Veterinary immunology and immunopathology 1999;72(1-2):189-202.
1999: RP Braun; Lorne A Babiuk; BI Loehr
Particle-mediated DNA immunization of cattle confers long-lasting immunity against bovine herpesvirus-1.
Virology 1999;265(1):46-56.
1999: PJ Lewis; Lorne A Babiuk
Altering the cellular location of an antigen expressed by a DNA-based vaccine modulates the immune response.
Journal of virology 1999;73(12):10214-23.
1999: P Seshidhar Reddy; Neeraja Idamakanti; Lorne A Babiuk; M Mehtali; Suresh Kumar Tikoo
Porcine adenovirus-3 as a helper-dependent expression vector.
The Journal of general virology 1999;80 ( Pt 11)():2909-16.
1999: PJ Lewis; Lorne A Babiuk
Induction of immune responses to bovine herpesvirus type 1 gD in passively immune mice after immunization with a DNA-based vaccine.
The Journal of general virology 1999;80 ( Pt 11)():2829-37.
1999: P Seshidhar Reddy; Neeraja Idamakanti; Y Chen; Tyler A Whale; Lorne A Babiuk; M Mehtali; Suresh Kumar Tikoo
Replication-defective bovine adenovirus type 3 as an expression vector.
Journal of virology 1999;73(11):9137-44.
1999: Mohit K Baxi; Lorne A Babiuk; M Mehtali; Suresh Kumar Tikoo
Transcription map and expression of bovine herpesvirus-1 glycoprotein D in early region 4 of bovine adenovirus-3.
Virology 1999;261(1):143-52.
1999: Sylvia van Drunen Littel-van den Hurk; RP Braun; Brenda Karvonen; T King; D Yoo; Lorne A Babiuk
Immune responses and protection induced by DNA vaccines encoding bovine parainfluenza virus type 3 glycoproteins.
Virology 1999;260(1):35-46.
1999: M A Morsey; A G Van-Kessel; Y Mori; Y Popowych; Dale L Godson; M Campos; Lorne A Babiuk
Cytokine profiles following interaction between bovine alveolar macrophages and Pasteurella haemolytica.
Microbial pathogenesis 1999;26(6):325-31.
1999: Alexander N Zakhartchouk; C Pyne; George K Mutwiri; Z Papp; Maria E Baca-Estrada; Philip J Griebel; Lorne A Babiuk; Suresh Kumar Tikoo
Mucosal immunization of calves with recombinant bovine adenovirus-3: induction of protective immunity to bovine herpesvirus-1.
The Journal of general virology 1999;80 ( Pt 5)():1263-9.
1999: Neeraja Idamakanti; P Seshidhar Reddy; Lorne A Babiuk; Suresh Kumar Tikoo
Transcription mapping and characterization of 284R and 121R proteins produced from early region 3 of bovine adenovirus type 3.
Virology 1999;256(2):351-9.
1999: Suresh K Mittal; Suresh Kumar Tikoo; J Van Donkersgoed; Terry K Beskorwayne; Dale L Godson; Lorne A Babiuk
Experimental inoculation of heifers with bovine adenovirus type 3.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1999;63(2):153-6.
1999: Lorne A Babiuk
Broadening the approaches to developing more effective vaccines.
Vaccine 1999;17(13-14):1587-95.
1999: P Seshidhar Reddy; Neeraja Idamakanti; BH Hyun; Suresh Kumar Tikoo; Lorne A Babiuk
Development of porcine adenovirus-3 as an expression vector.
The Journal of general virology 1999;80 ( Pt 3)():563-70.
1999: Z Papp; Lorne A Babiuk; Maria E Baca-Estrada
The effect of pre-existing adenovirus-specific immunity on immune responses induced by recombinant adenovirus expressing glycoprotein D of bovine herpesvirus type 1.
Vaccine 1999;17(7-8):933-43.
1999: P Wright; R Braun; Lorne A Babiuk; S D Littel-van den Hurk; Terence Moyana; Changyu Zheng; Y Chen; Jim Xiang
Adenovirus-mediated TNF-alpha gene transfer induces significant tumor regression in mice.
Cancer biotherapy & radiopharmaceuticals 1999;14(1):49-57.
1999: P Seshidhar Reddy; Y Chen; Neeraja Idamakanti; C Pyne; Lorne A Babiuk; Suresh Kumar Tikoo
Characterization of early region 1 and pIX of bovine adenovirus-3.
Virology 1999;253(2):299-308.
1999: PJ Lewis; Lorne A Babiuk
DNA vaccines: a review.
Advances in virus research 1999;54():129-88.
1999: Nagendra R Hegde; Muralidhar S Deshpande; D L Godson; Lorne A Babiuk; Subramaniam Srikumaran
Bovine lymphocyte antigen-A11--specific peptide motif as a means to identify cytotoxic T-lymphocyte epitopes of bovine herpesvirus 1.
Viral immunology 1999;12(2):149-61.
1999: Z Papp; Lorne A Babiuk; Maria E Baca-Estrada
Antigen-specific cytokine and antibody isotype profiles induced by mucosal and systemic immunization with recombinant adenoviruses.
Viral immunology 1999;12(2):107-16.
1999: Sylvia van Drunen Littel-van den Hurk; RP Braun; PJ Lewis; Brenda Karvonen; Lorne A Babiuk; Philip J Griebel
Immunization of neonates with DNA encoding a bovine herpesvirus glycoprotein is effective in the presence of maternal antibodies.
Viral immunology 1999;12(1):67-77.
1999: Lorne A Babiuk; J Lewis; S van den Hurk; R Braun
DNA immunization: present and future.
Advances in veterinary medicine 1999;41():163-79.
1998: R Braun; Lorne A Babiuk
Compatibility of plasmids expressing different antigens in a single DNA vaccine formulation.
The Journal of general virology 1998;79 ( Pt 12)():2965-70.
1998: P Seshidhar Reddy; Neeraja Idamakanti; J Y Song; JB Lee; BH Hyun; J H Park; S H Cha; Y T Bae; Suresh Kumar Tikoo; Lorne A Babiuk
Nucleotide sequence and transcription map of porcine adenovirus type 3.
Virology 1998;251(2):414-26.
1998: P Seshidhar Reddy; Neeraja Idamakanti; J Y Song; JB Lee; BH Hyun; J H Park; S H Cha; Suresh Kumar Tikoo; Lorne A Babiuk
Sequence and transcription map analysis of early region-1 of porcine adenovirus type-3.
Virus research 1998;58(1-2):97-106.
1998: Alexander N Zakhartchouk; P Seshidhar Reddy; Mohit K Baxi; Maria E Baca-Estrada; M Mehtali; Lorne A Babiuk; Suresh Kumar Tikoo
Construction and characterization of E3-deleted bovine adenovirus type 3 expressing full-length and truncated form of bovine herpesvirus type 1 glycoprotein gD.
Virology 1998;250(1):220-9.
1998: Marianna Foldvari; Samuel Attah-Poku; J Hu; Q Li; H Hughes; Lorne A Babiuk; S Kruger
Palmitoyl derivatives of interferon alpha: potential for cutaneous delivery.
Journal of pharmaceutical sciences 1998;87(10):1203-8.
1998: MK Ijaz; MS Nur-E-Kamal; FK Dar; SA Uduman; Mark Redmond; Samuel Attah-Poku; D Dent; Lorne A Babiuk
Inhibition of rotavirus infection in vitro and in vivo by a synthetic peptide from VP4.
Vaccine 1998;16(9-10):916-20.
1998: RP Braun; PJ Lewis; Brenda Karvonen; Maria E Baca-Estrada; Marlene Snider; DH McCartney; T Watts; Lorne A Babiuk
Intradermal immunization with a bovine herpesvirus-1 DNA vaccine induces protective immunity in cattle.
The Journal of general virology 1998;79 ( Pt 4)():831-9.
1998: P Seshidhar Reddy; Neeraja Idamakanti; Alexander N Zakhartchouk; Mohit K Baxi; JB Lee; C Pyne; Lorne A Babiuk; Suresh Kumar Tikoo
Nucleotide sequence, genome organization, and transcription map of bovine adenovirus type 3.
Journal of virology 1998;72(2):1394-402.
1998: Suresh K Mittal; Suresh Kumar Tikoo; Jan V van den Hurk; M M Breker-Klassen; D Yoo; Lorne A Babiuk
Functional characterization of bovine parainfluenza virus type 3 hemagglutinin-neuraminidase and fusion proteins expressed by adenovirus recombinants.
Intervirology 1998;41(6):253-60.
1998: JB Lee; Mohit K Baxi; Neeraja Idamakanti; P Seshidhar Reddy; Alexander N Zakhartchouk; C Pyne; Lorne A Babiuk; Suresh Kumar Tikoo
Genetic organization and DNA sequence of early region 4 of bovine adenovirus type 3.
Virus genes 1998;17(1):99-100.
1998: Z Papp; Lorne A Babiuk; Maria E Baca-Estrada
Induction of immunity in the respiratory tract and protection from bovine herpesvirus type 1 infection by different routes of immunization with recombinant adenovirus.
Viral immunology 1998;11(2):79-91.
1998: Mohit K Baxi; P Seshidhar Reddy; Alexander N Zakhartchouk; Neeraja Idamakanti; C Pyne; Lorne A Babiuk; Suresh Kumar Tikoo
Characterization of bovine adenovirus type 3 early region 2B.
Virus genes 1998;16(3):313-6.
1998: Lorne A Babiuk; PJ Lewis; S van Drunen Little-van den Hurk; S Tikoo; X Liang
Nucleic acid vaccines: veterinary applications.
Current topics in microbiology and immunology 1998;226():90-106.
1998: J Lee; Lorne A Babiuk; D Yoo
A neutralizing monoclonal antibody to bovine rotavirus VP8 neutralizes rotavirus infection without inhibiting virus attachment to MA-104 cells.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1998;62(1):63-7.
1998: J Lee; D Yoo; Mark Redmond; Samuel Attah-Poku; Jan V van den Hurk; Lorne A Babiuk
Characterization of the interaction between VP8 of bovine rotavirus C486 and cellular components on MA-104 cells and erythrocytes.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1998;62(1):56-62.
1997: Z Papp; Dorothy M Middleton; S K Mittal; Lorne A Babiuk; Maria E Baca-Estrada
Mucosal immunization with recombinant adenoviruses: induction of immunity and protection of cotton rats against respiratory bovine herpesvirus type 1 infection.
The Journal of general virology 1997;78 ( Pt 11)():2933-43.
1997: Maria E Baca-Estrada; Marianna Foldvari; Marlene Snider; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk
Effect of IL-4 and IL-12 liposomal formulations on the induction of immune response to bovine herpesvirus type-1 glycoprotein D.
Vaccine 1997;15(16):1753-60.
1997: X Liang; B Chow; Lorne A Babiuk
Study of immunogenicity and virulence of bovine herpesvirus 1 mutants deficient in the UL49 homolog, UL49.5 homolog and dUTPase genes in cattle.
Vaccine 1997;15(10):1057-64.
1997: PJ Lewis; G J Cox; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk
Polynucleotide vaccines in animals: enhancing and modulating responses.
Vaccine 1997;15(8):861-4.
1997: Y Li; Sylvia van Drunen Littel-van den Hurk; X Liang; Lorne A Babiuk
Functional analysis of the transmembrane anchor region of bovine herpesvirus 1 glycoprotein gB.
Virology 1997;228(1):39-54.
1997: S Suradhat; D Yoo; Lorne A Babiuk; Philip J Griebel; Maria E Baca-Estrada
DNA immunization with a bovine rotavirus VP4 gene induces a Th1-like immune response in mice.
Viral immunology 1997;10(3):117-27.
1997: Maria E Baca-Estrada; Lorne A Babiuk; D Yoo
Hemagglutinin-esterase glycoprotein gene of bovine corona virus delivered by adenovirus vector induces mucosal immunity in cotton rats.
Advances in experimental medicine and biology 1997;412():431-3.
1997: Sylvia van Drunen Littel-van den Hurk; Suresh Kumar Tikoo; Jan V van den Hurk; Lorne A Babiuk; J Van Donkersgoed
Protective immunity in cattle following vaccination with conventional and marker bovine herpesvirus-1 (BHV1) vaccines.
Vaccine 1997;15(1):36-44.
1996: L M Warren; Lorne A Babiuk; M Campos
Effects of BHV-1 on PMN adhesion to bovine lung endothelial cells.
Veterinary immunology and immunopathology 1996;55(1-3):73-82.
1996: Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk; Suresh Kumar Tikoo
Immunology of bovine herpesvirus 1 infection.
Veterinary microbiology 1996;53(1-2):31-42.
1996: Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk; Suresh Kumar Tikoo; P J Lewis; X Liang
Novel viral vaccines for livestock.
Veterinary immunology and immunopathology 1996;54(1-4):355-63.
1996: Andrew G Van Kessel; Dale L Godson; Maria E Baca-Estrada; M A Morsey; H P Hughes; Richard Harland; D E Shuster; Michael Daley; Lorne A Babiuk
Effect of recombinant bovine interleukin-1 beta in normal calves and in calves infected with bovine herpesvirus type 1.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(11):881-90.
1996: Suresh K Mittal; Z Papp; Suresh Kumar Tikoo; Maria E Baca-Estrada; D Yoo; M Benko; Lorne A Babiuk
Induction of systemic and mucosal immune responses in cotton rats immunized with human adenovirus type 5 recombinants expressing the full and truncated forms of bovine herpesvirus type 1 glycoprotein gD.
Virology 1996;222(2):299-309.
1996: Y Li; Sylvia van Drunen Littel-van den Hurk; X Liang; Lorne A Babiuk
The cytoplasmic domain of bovine herpesvirus 1 glycoprotein B is important for maintaining conformation and the high-affinity binding site of gB.
Virology 1996;222(1):262-8.
1996: M M Breker-Klassen; D Yoo; Lorne A Babiuk
Comparisons of the F and HN gene sequences of different strains of bovine parainfluenza virus type 3: relationship to phenotype and pathogenicity.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1996;60(3):228-36.
1996: Sylvia van Drunen Littel-van den Hurk; S Khattar; Suresh Kumar Tikoo; Lorne A Babiuk; E Baranowski; D Plainchamp; Etienne Thiry
Glycoprotein H (gII/gp108) and glycoprotein L form a functional complex which plays a role in penetration, but not in attachment, of bovine herpesvirus 1.
The Journal of general virology 1996;77 ( Pt 7)():1515-20.
1996: C Raggo; D R Fitzpatrick; Lorne A Babiuk; X Liang
Expression of bovine interleukin-1 beta in a bovine herpesvirus-1 vector: in vitro analysis.
Virology 1996;221(1):78-86.
1996: Dale L Godson; M Campos; Samuel Attah-Poku; Mark Redmond; D M Cordeiro; M S Sethi; Richard Harland; Lorne A Babiuk
Serum haptoglobin as an indicator of the acute phase response in bovine respiratory disease.
Veterinary immunology and immunopathology 1996;51(3-4):277-92.
1996: M Jiang; Lorne A Babiuk; Andrew A Potter
Cloning, sequencing and expression of the CAMP factor gene of Streptococcus uberis.
Microbial pathogenesis 1996;20(5):297-307.
1996: S K Khattar; S van Drunen Littel-van den Harke; Samuel Attah-Poku; Lorne A Babiuk; Suresh Kumar Tikoo
Identification and characterization of a bovine herpesvirus-1 (BHV-1) glycoprotein gL which is required for proper antigenicity, processing, and transport of BHV-1 glycoprotein gH.
Virology 1996;219(1):66-76.
1996: M A Morsey; Y Popowych; J Kowalski; G Gerlach; Dale L Godson; M Campos; Lorne A Babiuk
Molecular cloning and expression of bovine interleukin-8.
Microbial pathogenesis 1996;20(4):203-12.
1996: Y Li; X Liang; Sylvia van Drunen Littel-van den Hurk; Samuel Attah-Poku; Lorne A Babiuk
Glycoprotein Bb, the N-terminal subunit of bovine herpesvirus 1 gB, can bind to heparan sulfate on the surfaces of Madin-Darby bovine kidney cells.
Journal of virology 1996;70(3):2032-7.
1996: X Liang; Barbara L Chow; C Raggo; Lorne A Babiuk
Bovine herpesvirus 1 UL49.5 homolog gene encodes a novel viral envelope protein that forms a disulfide-linked complex with a second virion structural protein.
Journal of virology 1996;70(3):1448-54.
1996: A Khadr; Suresh Kumar Tikoo; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Sequence and expression of a bovine herpesvirus-1 gene homologous to the glycoprotein K-encoding gene of herpes simplex virus-1.
Gene 1996;168(2):189-93.
1996: Y Li; Sylvia van Drunen Littel-van den Hurk; X Liang; Lorne A Babiuk
Production and characterization of bovine herpesvirus 1 glycoprotein B ectodomain derivatives in an hsp70A gene promoter-based expression system.
Archives of virology 1996;141(10):2019-29.
1996: Maria E Baca-Estrada; Marlene Snider; Suresh Kumar Tikoo; Richard Harland; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Immunogenicity of bovine herpesvirus 1 glycoprotein D in mice: effect of antigen form on the induction of cellular and humoral immune responses.
Viral immunology 1996;9(1):11-22.
1996: Suresh K Mittal; Dorothy M Middleton; Suresh Kumar Tikoo; L Prevec; F L Graham; Lorne A Babiuk
Pathology and immunogenicity in the cotton rat (Sigmodon hispidus) model after infection with a bovine adenovirus type 3 recombinant virus expressing the firefly luciferase gene.
The Journal of general virology 1996;77 ( Pt 1)():1-9.
1995: Lorne A Babiuk; PJ Lewis; G Cox; Sylvia van Drunen Littel-van den Hurk; Maria E Baca-Estrada; Suresh Kumar Tikoo
DNA immunization with bovine herpesvirus-1 genes.
Annals of the New York Academy of Sciences 1995;772():47-63.
1995: S K Khattar; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; Suresh Kumar Tikoo
Identification and transcriptional analysis of a 3'-coterminal gene cluster containing UL1, UL2, UL3, and UL3.5 open reading frames of bovine herpesvirus-1.
Virology 1995;213(1):28-37.
1995: Suresh K Mittal; Dorothy M Middleton; Suresh Kumar Tikoo; Lorne A Babiuk
Pathogenesis and immunogenicity of bovine adenovirus type 3 in cotton rats (Sigmodon hispidus).
Virology 1995;213(1):131-9.
1995: Dale L Godson; Maria E Baca-Estrada; Andrew G Van Kessel; H P Hughes; M A Morsy; J Van Donkersgoed; Richard Harland; D E Shuster; Michael Daley; Lorne A Babiuk
Regulation of bovine acute phase responses by recombinant interleukin-1 beta.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1995;59(4):249-55.
1995: J Lee; Lorne A Babiuk; Richard Harland; E Gibbons; Y Elazhary; D Yoo
Immunological response to recombinant VP8* subunit protein of bovine roravirus in pregnant cattle.
The Journal of general virology 1995;76 ( Pt 10)():2477-83.
1995: Maria E Baca-Estrada; X Liang; Lorne A Babiuk; D Yoo
Induction of mucosal immunity in cotton rats to haemagglutinin-esterase glycoprotein of bovine coronavirus by recombinant adenovirus.
Immunology 1995;86(1):134-40.
1995: Y Li; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; X Liang
Characterization of cell-binding properties of bovine herpesvirus 1 glycoproteins B, C, and D: identification of a dual cell-binding function of gB.
Journal of virology 1995;69(8):4758-68.
1995: M M Breker-Klassen; D Yoo; Suresh K Mittal; S D Sorden; Deborah M Haines; Lorne A Babiuk
Recombinant type 5 adenoviruses expressing bovine parainfluenza virus type 3 glycoproteins protect Sigmodon hispidus cotton rats from bovine parainfluenza virus type 3 infection.
Journal of virology 1995;69(7):4308-15.
1995: X Liang; Barbara L Chow; Y Li; C Raggo; D Yoo; Samuel Attah-Poku; Lorne A Babiuk
Characterization of bovine herpesvirus 1 UL49 homolog gene and product: bovine herpesvirus 1 UL49 homolog is dispensable for virus growth.
Journal of virology 1995;69(6):3863-7.
1995: M K Ijaz; T O Alkarmi; M I Sabara; P J Frenchick; A A el Mekki; M Naiem; MS Nur-E-Kamal; P M Frossard; FK Dar; Lorne A Babiuk
Characterization of a synthetic peptide mimicking trypsin-cleavage site of rotavirus VP4.
Comparative immunology, microbiology and infectious diseases 1995;18(3):145-60.
1995: Maria E Baca-Estrada; Dale L Godson; H P Hughes; J Van Donkersgoed; Andrew G Van Kessel; Richard Harland; D E Shuster; M Daley; Lorne A Babiuk
Effect of recombinant bovine interleukin-1 beta on viral/bacterial pneumonia in cattle.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(5):431-9.
1995: X Liang; C Pyne; Y Li; Lorne A Babiuk; J Kowalski
Delineation of the essential function of bovine herpesvirus 1 gD: an indication for the modulatory role of gD in virus entry.
Virology 1995;207(2):429-41.
1995: M K Ijaz; T O Alkarmi; A W el-Mekki; S H Galadari; FK Dar; Lorne A Babiuk
Priming and induction of anti-rotavirus antibody response by synthetic peptides derived from VP7 and VP4.
Vaccine 1995;13(4):331-8.
1995: Sylvia van Drunen Littel-van den Hurk; S Garzon; Jan V van den Hurk; Lorne A Babiuk; Peter Tijssen
The role of the major tegument protein VP8 of bovine herpesvirus-1 in infection and immunity.
Virology 1995;206(1):413-25.
1995: D Yoo; M D Parker; G J Cox; Lorne A Babiuk
Zinc-binding of the cysteine-rich domain encoded in the open reading frame of 1B of the RNA polymerase gene of coronavirus.
Advances in experimental medicine and biology 1995;380():437-42.
1995: Suresh Kumar Tikoo; M Campos; Y I Popowych; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk
Lymphocyte proliferative responses to recombinant bovine herpes virus type 1 (BHV-1) glycoprotein gD (gIV) in immune cattle: identification of a T cell epitope.
Viral immunology 1995;8(1):19-25.
1995: Suresh K Mittal; L Prevec; F L Graham; Lorne A Babiuk
Development of a bovine adenovirus type 3-based expression vector.
The Journal of general virology 1995;76 ( Pt 1)():93-102.
1995: Suresh Kumar Tikoo; M Campos; Lorne A Babiuk
Bovine herpesvirus 1 (BHV-1): biology, pathogenesis, and control.
Advances in virus research 1995;45():191-223.
1994: Sylvia van Drunen Littel-van den Hurk; J Van Donkersgoed; J Kowalski; Jan V van den Hurk; Richard Harland; Lorne A Babiuk; T J Zamb
A subunit gIV vaccine, produced by transfected mammalian cells in culture, induces mucosal immunity against bovine herpesvirus-1 in cattle.
Vaccine 1994;12(14):1295-302.
1994: H P Hughes; M Campos; L McDougall; Terry K Beskorwayne; Andrew A Potter; Lorne A Babiuk
Regulation of major histocompatibility complex class II expression by Pasteurella haemolytica leukotoxin.
Infection and immunity 1994;62(5):1609-15.
1994: M K Ijaz; M I Sabara; T Alkarmi; P J Frenchick; K F Ready; FK Dar; Lorne A Babiuk
Molecular determinants of rotavirus virulence: localization of a potential virulence site in a murine rotavirus VP4.
Comparative immunology, microbiology and infectious diseases 1994;17(2):99-110.
1994: H P Hughes; S Rossow; M Campos; A Rossi-Campos; S Janssen; Dale L Godson; B Daflon; M J Voirol; C Gerber; Lorne A Babiuk
A slow release formulation for recombinant bovine interferon alpha I-1.
Antiviral research 1994;23(1):33-44.
1993: M K Ijaz; M I Sabara; T Alkarmi; P J Frenchick; K F Ready; M Longson; FK Dar; Lorne A Babiuk
Characterization of two rotaviruses differing in their in vitro and in vivo virulence.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1993;55(6):963-71.
1993: Sylvia van Drunen Littel-van den Hurk; Suresh Kumar Tikoo; X Liang; Lorne A Babiuk
Bovine herpesvirus-1 vaccines.
Immunology and cell biology 1993;71 ( Pt 5)():405-20.
1993: G J Cox; T J Zamb; Lorne A Babiuk
Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA.
Journal of virology 1993;67(9):5664-7.
1993: M Campos; Dale L Godson; H Hughes; Lorne A Babiuk; L Sordillo
The role of biological response modifiers in disease control.
Journal of dairy science 1993;76(8):2407-17.
1993: X Liang; M Tang; T J Zamb; Lorne A Babiuk; J Kowalski; M L Tykocinski
Expression of glycoprotein gIII-human decay-accelerating factor chimera on the bovine herpesvirus 1 virion via a glycosyl phosphatidylinositol-based membrane anchor.
Journal of virology 1993;67(8):4896-904.
1993: X Liang; M Tang; B Manns; Lorne A Babiuk; T J Zamb
Identification and deletion mutagenesis of the bovine herpesvirus 1 dUTPase gene and a gene homologous to herpes simplex virus UL49.5.
Virology 1993;195(1):42-50.
1993: X Liang; Lorne A Babiuk; T J Zamb
Mapping of heparin-binding structures on bovine herpesvirus 1 and pseudorabies virus gIII glycoproteins.
Virology 1993;194(1):233-43.
1993: Suresh Kumar Tikoo; T J Zamb; Lorne A Babiuk
Analysis of bovine herpesvirus 1 glycoprotein gIV truncations and deletions expressed by recombinant vaccinia viruses.
Journal of virology 1993;67(4):2103-9.
1993: Suresh Kumar Tikoo; M D Parker; Jan V van den Hurk; J Kowalski; T J Zamb; Lorne A Babiuk
Role of N-linked glycans in antigenicity, processing, and cell surface expression of bovine herpesvirus 1 glycoprotein gIV.
Journal of virology 1993;67(2):726-33.
1993: J A Ellis; D Godson; M Campos; M Sileghem; Lorne A Babiuk
Capture immunoassay for ruminant tumor necrosis factor-alpha: comparison with bioassay.
Veterinary immunology and immunopathology 1993;35(3-4):289-300.
1993: Mark Redmond; M K Ijaz; M D Parker; M I Sabara; D Dent; E Gibbons; Lorne A Babiuk
Assembly of recombinant rotavirus proteins into virus-like particles and assessment of vaccine potential.
Vaccine 1993;11(2):273-81.
1993: Sylvia van Drunen Littel-van den Hurk; M D Parker; B Massie; Jan V van den Hurk; Richard Harland; Lorne A Babiuk; T J Zamb
Protection of cattle from BHV-1 infection by immunization with recombinant glycoprotein gIV.
Vaccine 1993;11(1):25-35.
1993: J Kowalski; Scott A Gilbert; Sylvia van Drunen Littel-van den Hurk; Jan V van den Hurk; Lorne A Babiuk; T J Zamb
Heat-shock promoter-driven synthesis of secreted bovine herpesvirus glycoproteins in transfected cells.
Vaccine 1993;11(11):1100-7.
1992: D Yoo; F L Graham; L Prevec; M D Parker; M Benkö; T Zamb; Lorne A Babiuk
Synthesis and processing of the haemagglutinin-esterase glycoprotein of bovine coronavirus encoded in the E3 region of adenovirus.
The Journal of general virology 1992;73 ( Pt 10)():2591-600.
1992: Sylvia van Drunen Littel-van den Hurk; M D Parker; D R Fitzpatrick; Jan V van den Hurk; M Campos; Lorne A Babiuk; T Zamb
Structural, functional, and immunological characterization of bovine herpesvirus-1 glycoprotein gl expressed by recombinant baculovirus.
Virology 1992;190(1):378-92.
1992: C G Pfeifer; M Campos; Terry K Beskorwayne; Lorne A Babiuk; Andrew A Potter
Effect of Haemophilus somnus on phagocytosis and hydrogen peroxide production by bovine polymorphonuclear leukocytes.
Microbial pathogenesis 1992;13(3):191-202.
1992: X Liang; Lorne A Babiuk; T J Zamb
An in vivo study of a glycoprotein gIII-negative bovine herpesvirus 1 (BHV-1) mutant expressing beta-galactosidase: evaluation of the role of gIII in virus infectivity and its use as a vector for mucosal immunization.
Virology 1992;189(2):629-39.
1992: M Campos; C R Rossi; H Bielefeldt Ohmann; Terry K Beskorwayne; N Rapin; Lorne A Babiuk
Characterization and activation requirements of bovine lymphocytes acquiring cytotoxic activity after interleukin-2 treatment.
Veterinary immunology and immunopathology 1992;32(3-4):205-23.
1992: J C Schuh; H Bielefeldt Ohmann; Lorne A Babiuk; C E Doige
Bovine herpesvirus-1-induced pharyngeal tonsil lesions in neonatal and weanling calves.
Journal of comparative pathology 1992;106(3):243-53.
1992: Jim Xiang; Z Pan; S Attah-Poku; Lorne A Babiuk; Y Zhang; E Liu
Production of hybrid bispecific antibody recognizing human colorectal carcinoma and CD3 antigen.
Molecular biotherapy 1992;4(1):15-23.
1992: H P Hughes; M Campos; Andrew A Potter; Lorne A Babiuk
Molecular chimerization of Pasteurella haemolytica leukotoxin to interleukin-2: effects on cytokine and antigen function.
Infection and immunity 1992;60(2):565-70.
1992: L M Sordillo; M Snider; Lorne A Babiuk
Physiological and morphological changes in bovine mammary glands following intramammary infusion of recombinant interferon-gamma.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1992;56(1):22-7.
1992: M Campos; H P Hughes; Dale L Godson; L M Sordillo; A Rossi-Campos; Lorne A Babiuk
Clinical and immunological effects of single bolus administration of recombinant interleukin-2 in cattle.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1992;56(1):10-5.
1992: M Campos; Philip J Griebel; H Bielefeldt Ohmann; Lorne A Babiuk
Cell-mediated cytotoxic responses in lungs following a primary bovine herpes virus type 1 infection.
Immunology 1992;75(1):47-52.
1992: H P Hughes; M Campos; Sylvia van Drunen Littel-van den Hurk; T Zamb; L M Sordillo; Dale L Godson; Lorne A Babiuk
Multiple administration with interleukin-2 potentiates antigen-specific responses to subunit vaccination with bovine herpesvirus-1 glycoprotein IV.
Vaccine 1992;10(4):226-30.
1992: P J Frenchick; M I Sabara; K F Ready; Lorne A Babiuk
Biochemical and immunological characterization of a novel peptide carrier system using rotavirus VP6 particles.
Vaccine 1992;10(11):783-91.
1992: Dale L Godson; M Campos; Lorne A Babiuk
The role of bovine intraepithelial leukocyte-mediated cytotoxicity in enteric antiviral defense.
Viral immunology 1992;5(1):1-13.
1992: L M Sordillo; G Afseth; G Davies; Lorne A Babiuk
Effects of recombinant granulocyte-macrophage colony-stimulating factor on bovine peripheral blood and mammary gland neutrophil function in vitro.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1992;56(1):16-21.
1992: H P Hughes; Lorne A Babiuk
The adjuvant potential of cytokines.
Biotechnology therapeutics 1992;3(3-4):101-17.
1991: L M Sordillo; M Snider; H Hughes; G Afseth; M Campos; Lorne A Babiuk
Pathological changes in bovine mammary glands following intramammary infusion of recombinant interleukin-2.
Journal of dairy science 1991;74(12):4164-74.
1991: Lorne A Babiuk; L M Sordillo; M Campos; H P Hughes; A Rossi-Campos; Richard Harland
Application of interferons in the control of infectious diseases of cattle.
Journal of dairy science 1991;74(12):4385-98.
1991: G J Cox; M D Parker; Lorne A Babiuk
Bovine coronavirus nonstructural protein ns2 is a phosphoprotein.
Virology 1991;185(1):509-12.
1991: H P Hughes; M Campos; Dale L Godson; Sylvia van Drunen Littel-van den Hurk; L McDougall; N Rapin; T Zamb; Lorne A Babiuk
Immunopotentiation of bovine herpes virus subunit vaccination by interleukin-2.
Immunology 1991;74(3):461-6.
1991: L M Sordillo; M Campos; Lorne A Babiuk
Antibacterial activity of bovine mammary gland lymphocytes following treatment with interleukin-2.
Journal of dairy science 1991;74(10):3370-5.
1991: Dale L Godson; M Campos; Lorne A Babiuk
Non-major histocompatibility complex-restricted cytotoxicity of bovine coronavirus-infected target cells mediated by bovine intestinal intraepithelial leukocytes.
The Journal of general virology 1991;72 ( Pt 10)():2457-65.
1991: X P Liang; Lorne A Babiuk; T J Zamb
Pseudorabies virus gIII and bovine herpesvirus 1 gIII share complementary functions.
Journal of virology 1991;65(10):5553-7.
1991: H Bielefeldt Ohmann; Lorne A Babiuk; Richard Harland
Cytokine synergy with viral cytopathic effects and bacterial products during the pathogenesis of respiratory tract infection.
Clinical immunology and immunopathology 1991;60(2):153-70.
1991: D Yoo; M D Parker; J Song; G J Cox; D Deregt; Lorne A Babiuk
Structural analysis of the conformational domains involved in neutralization of bovine coronavirus using deletion mutants of the spike glycoprotein S1 subunit expressed by recombinant baculoviruses.
Virology 1991;183(1):91-8.
1991: L M Sordillo; Lorne A Babiuk
Controlling acute Escherichia coli mastitis during the periparturient period with recombinant bovine interferon gamma.
Veterinary microbiology 1991;28(2):189-98.
1991: L M Sordillo; Mark Redmond; M Campos; L Warren; Lorne A Babiuk
Cytokine activity in bovine mammary gland secretions during the periparturient period.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1991;55(3):298-301.
1991: M K Ijaz; Samuel Attah-Poku; Mark Redmond; M D Parker; M I Sabara; P Frenchick; Lorne A Babiuk
Heterotypic passive protection induced by synthetic peptides corresponding to VP7 and VP4 of bovine rotavirus.
Journal of virology 1991;65(6):3106-13.
1991: Mark Redmond; H B Ohmann; H P Hughes; M Sabara; P J Frenchick; S K Poku; M K Ijaz; M D Parker; Bernard Laarveld; Lorne A Babiuk
Rotavirus particles function as immunological carriers for the delivery of peptides from infectious agents and endogenous proteins.
Molecular immunology 1991;28(3):269-78.
1991: X P Liang; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk; D R Fitzpatrick; T J Zamb
Bovine herpesvirus 1 attachment to permissive cells is mediated by its major glycoproteins gI, gIII, and gIV.
Journal of virology 1991;65(3):1124-32.
1991: L M Sordillo; Lorne A Babiuk
Modulation of bovine mammary neutrophil function during the periparturient period following in vitro exposure to recombinant bovine interferon gamma.
Veterinary immunology and immunopathology 1991;27(4):393-402.
1991: D Yoo; M D Parker; Lorne A Babiuk
The S2 subunit of the spike glycoprotein of bovine coronavirus mediates membrane fusion in insect cells.
Virology 1991;180(1):395-9.
1991: Sylvia van Drunen Littel-van den Hurk; M D Parker; D R Fitzpatrick; T J Zamb; Jan V van den Hurk; M Campos; Richard Harland; Lorne A Babiuk
Expression of bovine herpesvirus 1 glycoprotein gIV by recombinant baculovirus and analysis of its immunogenic properties.
Journal of virology 1991;65(1):263-71.
1991: M Campos; H B Ohmann; N Rapin; Lorne A Babiuk
Demonstration of the in vitro antiviral properties of bovine lymphokine-activated killer (LAK) cells.
Viral immunology 1991;4(4):259-68.
1990: D Yoo; M D Parker; Lorne A Babiuk
Analysis of the S spike (peplomer) glycoprotein of bovine coronavirus synthesized in insect cells.
Virology 1990;179(1):121-8.
1990: Suresh Kumar Tikoo; D R Fitzpatrick; Lorne A Babiuk; T J Zamb
Molecular cloning, sequencing, and expression of functional bovine herpesvirus 1 glycoprotein gIV in transfected bovine cells.
Journal of virology 1990;64(10):5132-42.
1990: D L Hutchings; M Campos; L Qualtiere; Lorne A Babiuk
Inhibition of antigen-induced and interleukin-2-induced proliferation of bovine peripheral blood leukocytes by inactivated bovine herpes virus 1.
Journal of virology 1990;64(9):4146-51.
1990: Sylvia van Drunen Littel-van den Hurk; G Hughes; Lorne A Babiuk
The role of carbohydrate in the antigenic and immunogenic structure of bovine herpesvirus type 1 glycoproteins gI and gIV.
The Journal of general virology 1990;71 ( Pt 9)():2053-63.
1990: M D Parker; D Yoo; G J Cox; Lorne A Babiuk
Primary Structure of the S peplomer gene of bovine coronavirus and surface expression in insect cells.
The Journal of general virology 1990;71 ( Pt 8)():1885.
1990: Sylvia van Drunen Littel-van den Hurk; G A Gifford; Lorne A Babiuk
Epitope specificity of the protective immune response induced by individual bovine herpesvirus-1 glycoproteins.
Vaccine 1990;8(4):358-68.
1990: D R Fitzpatrick; M Snider; L McDougall; Terry K Beskorwayne; Lorne A Babiuk; T J Zamb; H Bielefeldt Ohmann
Molecular mimicry: a herpes virus glycoprotein antigenically related to a cell-surface glycoprotein expressed by macrophages, polymorphonuclear leucocytes, and platelets.
Immunology 1990;70(4):504-12.
1990: D R Fitzpatrick; T J Zamb; Lorne A Babiuk
Expression of bovine herpesvirus type 1 glycoprotein gI in transfected bovine cells induces spontaneous cell fusion.
The Journal of general virology 1990;71 ( Pt 5)():1215-9.
1990: D R Fitzpatrick; Mark Redmond; Samuel Attah-Poku; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; T J Zamb
Mapping of 10 epitopes on bovine herpesvirus type 1 glycoproteins gI and gIII.
Virology 1990;176(1):145-57.
1990: M D Parker; D Yoo; Lorne A Babiuk
Expression and secretion of the bovine coronavirus hemagglutinin-esterase glycoprotein by insect cells infected with recombinant baculoviruses.
Journal of virology 1990;64(4):1625-9.
1990: Philip J Griebel; H B Ohmann; M J Lawman; Lorne A Babiuk
The interaction between bovine herpesvirus type 1 and activated bovine T lymphocytes.
The Journal of general virology 1990;71 ( Pt 2)():369-77.
1990: M D Parker; D Yoo; G J Cox; Lorne A Babiuk
Primary structure of the S peplomer gene of bovine coronavirus and surface expression in insect cells.
The Journal of general virology 1990;71 ( Pt 2)():263-70.
1990: M K Ijaz; D Dent; Lorne A Babiuk
Neuroimmunomodulation of in vivo anti-rotavirus humoral immune response.
Journal of neuroimmunology 1990;26(2):159-71.
1990: H B Ohmann; M Campos; L McDougall; M J Lawman; Lorne A Babiuk
Expression of tumor necrosis factor-alpha receptors on bovine macrophages, lymphocytes and polymorphonuclear leukocytes, internalization of receptor-bound ligand, and some functional effects.
Lymphokine research 1990;9(1):43-58.
1990: M D Parker; G J Cox; D Yoo; D R Fitzpatrick; Lorne A Babiuk
The haemagglutinin of bovine coronavirus exhibits significant similarity to the haemagglutinin of type C influenza virus.
Advances in experimental medicine and biology 1990;276():103-8.
1989: H Bielefeldt Ohmann; M Campos; M Snider; N Rapin; Terry K Beskorwayne; Y Popowych; M J Lawman; A Rossi; Lorne A Babiuk
Effect of chronic administration of recombinant bovine tumor necrosis factor to cattle.
Veterinary pathology 1989;26(6):462-72.
1989: D R Fitzpatrick; Lorne A Babiuk; T J Zamb
Nucleotide sequence of bovine herpesvirus type 1 glycoprotein gIII, a structural model for gIII as a new member of the immunoglobulin superfamily, and implications for the homologous glycoproteins of other herpesviruses.
Virology 1989;173(1):46-57.
1989: A M Nagi; Lorne A Babiuk
Isolation, characterization and in vitro mitogenic stimulation of peripheral blood lymphocytes from an American buffalo.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1989;53(4):493-6.
1989: M K Ijaz; D Dent; D Haines; Lorne A Babiuk
Development of a murine model to study the pathogenesis of rotavirus infection.
Experimental and molecular pathology 1989;51(2):186-204.
1989: A M Nagi; Lorne A Babiuk
Interleukin-2 production by mitogen-stimulated intestinal mucosal leukocytes from cattle.
American journal of veterinary research 1989;50(9):1591-7.
1989: Philip J Griebel; A P Gee; L Qualtiere; M J Lawman; Lorne A Babiuk
Negative enrichment of bovine T lymphocytes with monoclonal antibodies and magnetic microspheres.
Veterinary immunology and immunopathology 1989;22(2):161-73.
1989: A M Nagi; Lorne A Babiuk
Peanut agglutinin (PNA): binding and stimulation of bovine intestinal and peripheral blood leukocytes.
Veterinary immunology and immunopathology 1989;22(1):67-78.
1989: A M Nagi; Lorne A Babiuk
Characterization of surface markers of bovine gut mucosal leukocytes using monoclonal antibodies.
Veterinary immunology and immunopathology 1989;22(1):1-14.
1989: A M Nagi; Lorne A Babiuk
Concanavalin A-induced suppressor cell activity in intestinal mucosal leukocytes obtained from healthy cows.
American journal of veterinary research 1989;50(8):1266-71.
1989: G J Cox; M D Parker; Lorne A Babiuk
The sequence of cDNA of bovine coronavirus 32K nonstructural gene.
Nucleic acids research 1989;17(14):5847.
1989: Sylvia van Drunen Littel-van den Hurk; T Zamb; Lorne A Babiuk
Synthesis, cellular location, and immunogenicity of bovine herpesvirus 1 glycoproteins gI and gIII expressed by recombinant vaccinia virus.
Journal of virology 1989;63(5):2159-68.
1989: H B Ohmann; M Campos; D R Fitzpatrick; N Rapin; Lorne A Babiuk
A neutrophil-derived antiviral protein: induction requirements and biological properties.
Journal of virology 1989;63(5):1916-23.
1989: M Campos; H B Ohmann; D Hutchings; N Rapin; Lorne A Babiuk; M J Lawman
Role of interferon-gamma in inducing cytotoxicity of peripheral blood mononuclear leukocytes to bovine herpesvirus type 1 (BHV-1)-infected cells.
Cellular immunology 1989;120(1):259-69.
1989: Philip J Griebel; H Bielefeldt Ohmann; M Campos; L Qualtiere; W C Davis; M J Lawman; Lorne A Babiuk
Bovine peripheral blood leukocyte population dynamics following treatment with recombinant bovine interferon-alpha I1.
Journal of interferon research 1989;9(2):245-57.
1989: H Bielefeldt Ohmann; M Campos; Richard Harland; Philip J Griebel; Lorne A Babiuk
2',5' oligoadenylate synthetase activity in bovine peripheral blood mononuclear cells following bovine herpesvirus type-1-induced respiratory disease: a prognostic indicator?
Journal of interferon research 1989;9(2):159-66.
1989: H B Ohmann; M Campos; Philip J Griebel; Lorne A Babiuk
2'-5' oligo-A-synthetase activity in bovine peripheral blood leukocytes and alveolar macrophages exposed to recombinant interferons and tumor necrosis factor-alpha.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1989;53(2):161-6.
1989: D Deregt; G A Gifford; M K Ijaz; T C Watts; J E Gilchrist; Deborah M Haines; Lorne A Babiuk
Monoclonal antibodies to bovine coronavirus glycoproteins E2 and E3: demonstration of in vivo virus-neutralizing activity.
The Journal of general virology 1989;70 ( Pt 4)():993-8.
1989: D Deregt; M D Parker; G C Cox; Lorne A Babiuk
Mapping of neutralizing epitopes to fragments of the bovine coronavirus E2 protein by proteolysis of antigen-antibody complexes.
The Journal of general virology 1989;70 ( Pt 3)():647-58.
1989: A M Nagi; Lorne A Babiuk
Recombinant human interleukin-2-induced mitogenic proliferation of in vitro unstimulated bovine intestinal lymphocytes.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1989;53(1):68-75.
1989: M D Parker; G J Cox; D Deregt; D R Fitzpatrick; Lorne A Babiuk
Cloning and in vitro expression of the gene for the E3 haemagglutinin glycoprotein of bovine coronavirus.
The Journal of general virology 1989;70 ( Pt 1)():155-64.
1988: M Campos; H B Ohmann; G Hughes; Lorne A Babiuk; M J Lawman
Studies on the in vitro biological activities of recombinant bovine tumor necrosis factor (rBoTNF) alpha. I. Synergistic antiviral efficacy of rBoTNF alpha, recombinant bovine interferon gamma (rBoIFN gamma) and their combination.
Antiviral research 1988;10(1-3):71-81.
1988: K F Ready; M I Sabara; Lorne A Babiuk
In vitro assembly of the outer capsid of bovine rotavirus is calcium-dependent.
Virology 1988;167(1):269-73.
1988: D R Fitzpatrick; T Zamb; M D Parker; Sylvia van Drunen Littel-van den Hurk; Lorne A Babiuk; M J Lawman
Expression of bovine herpesvirus 1 glycoproteins gI and gIII in transfected murine cells.
Journal of virology 1988;62(11):4239-48.
1988: A M Nagi; Lorne A Babiuk
Modulation of some Peyer's patch leukocyte functions following in vitro exposure to recombinant bovine alpha- and gamma-interferon.
Immunobiology 1988;177(4-5):329-38.
1988: A M Nagi; Lorne A Babiuk
Effects of recombinant bovine interferons-alpha and -gamma on some in vitro immune functions of bovine intraepithelial and lamina propria leukocytes.
Journal of interferon research 1988;8(4):495-505.
1988: H B Ohmann; M Campos; M J Lawman; Lorne A Babiuk
Induction of MHC class II antigens on bovine cells of nonlymphoid origin by recombinant bovine interferon-gamma and tumor necrosis factor-alpha.
Journal of interferon research 1988;8(4):451-62.
1988: A M Nagi; Lorne A Babiuk
Response of bovine intestinal leukocytes to recombinant bovine interleukin-2.
Journal of biological regulators and homeostatic agents 1988;2(3):125-33.
1988: H Bielefeldt Ohmann; Lorne A Babiuk
Influence of interferons alpha I1 and gamma and of tumour necrosis factor on persistent infection with bovine viral diarrhoea virus in vitro.
The Journal of general virology 1988;69 ( Pt 6)():1399-403.
1988: A M Nagi; Lorne A Babiuk
Preparation, purification and characterization of bovine Peyer's patch leukocytes.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1988;52(2):249-57.
1988: H Bielefeldt-Ohmann; M Sabara; M J Lawman; Philip J Griebel; Lorne A Babiuk
A monoclonal antibody detects macrophage maturation antigen which appears independently of class II antigen expression. Reactivity of monoclonal EBM11 with bovine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2201-9.
1988: H B Ohmann; Lorne A Babiuk
Induction of receptors for complement and immunoglobulins by herpesviruses of various species.
Virus research 1988;9(4):335-42.
1988: Lorne A Babiuk; M J Lawman; H B Ohmann
Viral-bacterial synergistic interaction in respiratory disease.
Advances in virus research 1988;35():219-49.
1988: G Hughes; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Functional and topographical analyses of epitopes on bovine herpesvirus type 1 glycoprotein IV.
Archives of virology 1988;103(1-2):47-60.
1987: A M Nagi; Lorne A Babiuk
Bovine gut-associated lymphoid tissue--morphologic and functional studies. I. Isolation and characterization of leukocytes from the epithelium and lamina propria of bovine small intestine.
Journal of immunological methods 1987;105(1):23-37.
1987: M J Lawman; G Gifford; M Gyongyossy-Issa; R Dragan; J Heise; Lorne A Babiuk
Activity of polymorphonuclear (PMN) leukocytes during bovine herpes virus-1 induced respiratory disease: effect of recombinant bovine interferon alpha I1.
Antiviral research 1987;8(5-6):225-37.
1987: M K Ijaz; M I Sabara; P J Frenchick; Lorne A Babiuk
Effect of different routes of immunization with bovine rotavirus on lactogenic antibody response in mice.
Antiviral research 1987;8(5-6):283-97.
1987: D Deregt; Lorne A Babiuk
Monoclonal antibodies to bovine coronavirus: characteristics and topographical mapping of neutralizing epitopes on the E2 and E3 glycoproteins.
Virology 1987;161(2):410-20.
1987: D Deregt; M Sabara; Lorne A Babiuk
Structural proteins of bovine coronavirus and their intracellular processing.
The Journal of general virology 1987;68 ( Pt 11)():2863-77.
1987: M K Ijaz; M I Sabara; P J Frenchick; Lorne A Babiuk
Assessment of intestinal damage in rotavirus infected neonatal mice by a D-xylose absorption test.
Journal of virological methods 1987;18(2-3):153-7.
1987: Philip J Griebel; M Schoonderwoerd; Lorne A Babiuk
Ontogeny of the immune response: effect of protein energy malnutrition in neonatal calves.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1987;51(4):428-35.
1987: G D Mechor; C G Rousseaux; O M Radostits; Lorne A Babiuk; Lyall Petrie
Protection of newborn calves against fatal multisystemic infectious bovine rhinotracheitis by feeding colostrum from vaccinated cows.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1987;51(4):452-9.
1987: H B Ohmann; P E Baker; Lorne A Babiuk
Effect of dexamethasone on bovine leukocyte functions and bovine herpesvirus type-1 replication.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 1987;51(3):350-7.
1987: H B Ohmann; M J Lawman; Lorne A Babiuk
Bovine interferon: its biology and application in veterinary medicine.
Antiviral research 1987;7(4):187-210.
1987: Philip J Griebel; L Qualtiere; W C Davis; A Gee; H Bielefeldt Ohmann; M J Lawman; Lorne A Babiuk
T lymphocyte population dynamics and function following a primary bovine herpesvirus type-1 infection.
Viral immunology 1987;1(4):287-304.
1987: Philip J Griebel; L Qualtiere; W C Davis; M J Lawman; Lorne A Babiuk
Bovine peripheral blood leukocyte subpopulation dynamics following a primary bovine herpesvirus-1 infection.
Viral immunology 1987;1(4):267-86.
1987: D Deregt; M Sabara; Lorne A Babiuk
Monoclonal antibodies to two bovine coronavirus glycoproteins neutralize virus infectivity.
Advances in experimental medicine and biology 1987;218():473-4.
1987: M Sabara; K F Ready; P J Frenchick; Lorne A Babiuk
Biochemical evidence for the oligomeric arrangement of bovine rotavirus nucleocapsid protein and its possible significance in the immunogenicity of this protein.
The Journal of general virology 1987;68 ( Pt 1)():123-33.
1987: M J Lawman; Philip J Griebel; D L Hutchings; W C Davis; J Heise; L Qualtiere; Lorne A Babiuk
Generation of IL-2 dependent bovine cytotoxic T lymphocyte clones reactive against BHV-1 infected target cells: loss of genetic restriction and virus specificity.
Viral immunology 1987;1(3):163-76.
1985: Lorne A Babiuk; M Sabara; G R Hudson
Rotavirus and coronavirus infections in animals.
Progress in veterinary microbiology and immunology 1985;1():80-120.
1982: M Sabara; D Deregt; Lorne A Babiuk; V Misra
Genetic heterogeneity within individual bovine rotavirus isolates.
Journal of virology 1982;44(3):813-22.