Shyr-Te Ju

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Sharma Rahul; Deshmukh Umesh S; Zheng Lingjie; Fu Shu Man; Ju Shyr-Te
X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms.
Kinsey Gilbert R; Sharma Rahul; Huang Liping; Li Li; Vergis Amy L; Ye Hong; Ju Shyr-Te; Okusa Mark D
Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury.
Sharma Rahul; Sung Sun-sang Joe; Abaya Christian E; Ju Angela Chiao-Ying; Fu Shu Man; Ju Shyr-Te
IL-2 regulates CD103 expression on CD4+ T cells in Scurfy mice that display both CD103-dependent and independent inflammation.

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2009: Sharma Rahul; Deshmukh Umesh S; Zheng Lingjie; Fu Shu Man; Ju Shyr-Te
X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):3212-8.
2009: Kinsey Gilbert R; Sharma Rahul; Huang Liping; Li Li; Vergis Amy L; Ye Hong; Ju Shyr-Te; Okusa Mark D
Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN 2009;20(8):1744-53.
2009: Sharma Rahul; Sung Sun-sang Joe; Abaya Christian E; Ju Angela Chiao-Ying; Fu Shu Man; Ju Shyr-Te
IL-2 regulates CD103 expression on CD4+ T cells in Scurfy mice that display both CD103-dependent and independent inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):1065-73.
2009: Zhang Weici; Sharma Rahul; Ju Shyr-Te; He Xiao-Song; Tao Yanyan; Tsuneyama Koichi; Tian Zhigang; Lian Zhe-Xiong; Fu Shu Man; Gershwin M Eric
Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis.
Hepatology (Baltimore, Md.) 2009;49(2):545-52.
2009: Sharma Rahul; Sung Sun-sang Joe; Fu Shu Man; Ju Shyr-Te
Regulation of multi-organ inflammation in the regulatory T cell-deficient scurfy mice.
Journal of biomedical science 2009;16():20.
2008: Sharma Rahul; Ju Angela Chiao-Ying; Kung John T; Fu Shu Man; Ju Shyr-Te
Rapid and selective expansion of nonclonotypic T cells in regulatory T cell-deficient, foreign antigen-specific TCR-transgenic scurfy mice: antigen-dependent expansion and TCR analysis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):6934-41.
2008: Zheng Lingjie; Sharma Rahul; Kung John T; Deshmukh Umesh S; Jarjour Wael N; Fu Shu Man; Ju Shyr-Te
Pervasive and stochastic changes in the TCR repertoire of regulatory T-cell-deficient mice.
International immunology 2008;20(4):517-23.
2007: Zheng Lingjie; Sharma Rahul; Gaskin Felicia; Fu Shu Man; Ju Shyr-Te
A novel role of IL-2 in organ-specific autoimmune inflammation beyond regulatory T cell checkpoint: both IL-2 knockout and Fas mutation prolong lifespan of Scurfy mice but by different mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(12):8035-41.
2007: Sharma Rahul; Jarjour Wael N; Zheng Lingjie; Gaskin Felicia; Fu Shu Man; Ju Shyr-Te
Large functional repertoire of regulatory T-cell suppressible autoimmune T cells in scurfy mice.
Journal of autoimmunity 2007;29(1):10-9.
2007: Sharma Rahul; Zheng Lingjie; Deshmukh Umesh S; Jarjour Wael N; Sung Sun-Sang J; Fu Shu Man; Ju Shyr-Te
A regulatory T cell-dependent novel function of CD25 (IL-2Ralpha) controlling memory CD8(+) T cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1251-5.
2006: Sharma R; Zheng L; Guo X; Fu S M; Ju S-T; Jarjour W N
Novel animal models for Sjögren's syndrome: expression and transfer of salivary gland dysfunction from regulatory T cell-deficient mice.
Journal of autoimmunity 2006;27(4):289-96.
2006: Sung Sun-Sang J; Fu Shu Man; Rose C Edward; Gaskin Felicia; Ju Shyr-Te; Beaty Steven R
A major lung CD103 (alphaE)-beta7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2161-72.
2005: Sharma Rahul; Bagavant Harini; Jarjour Wael N; Sung Sun-Sang J; Ju Shyr-Te
The role of Fas in the immune system biology of IL-2R alpha knockout mice: interplay among regulatory T cells, inflammation, hemopoiesis, and apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1965-73.
2005: Jodo Satoshi; Pidiyar Vyankatesh J; Xiao Sheng; Furusaki Akira; Sharma Rahul; Koike Takao; Ju Shyr-Te
Fas ligand (CD178) cytoplasmic tail is a positive regulator of Fas ligand-mediated cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4470-4.
2004: Xiao Sheng; Deshmukh Umesh S; Jodo Satoshi; Koike Takao; Sharma Rahul; Furusaki Akiro; Sung Sun-sang J; Ju Shyr-Te
Novel negative regulator of expression in Fas ligand (CD178) cytoplasmic tail: evidence for translational regulation and against Fas ligand retention in secretory lysosomes.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5095-102.
2004: Xiao Sheng; Zhang Xingmin; Mann Koren K; Jodo Satoshi; Li Li; Jarjour Wael N; Marshak-Rothstein Ann; Sherr David H; Ju Shyr-Te
Changes in sensitivity of peripheral lymphocytes of autoimmune gld mice to FasL-mediated apoptosis reveal a mechanism for the preferential deletion of CD4-CD8-B220+ T cells.
International immunology 2004;16(5):759-66.
2003: Xiao Sheng; Sung Sun-Sang J; Fu Shu Man; Ju Shyr-Te
Combining Fas mutation with interleukin-2 deficiency prevents Colitis and Lupus: implicating interleukin-2 for auto-reactive T cell expansion and Fas ligand for colon epithelial cell death.
The Journal of biological chemistry 2003;278(52):52730-8.
2003: Jodo Satoshi; Kung John T; Xiao Sheng; Chan Derek V; Kobayashi Seiichi; Tateno Masatoshi; Lafyatis Robert; Ju Shyr-Te
Anti-CD95-induced lethality requires radioresistant Fcgamma RII+ cells. A novel mechanism for fulminant hepatic failure.
The Journal of biological chemistry 2003;278(9):7553-7.
2003: Joussen Antonia M; Poulaki Vassiliki; Mitsiades Nicholas; Cai Wen-yi; Suzuma Izumi; Pak John; Ju Shyr-Te; Rook Susan L; Esser Peter; Mitsiades Constantin S; Kirchhof Bernd; Adamis Anthony P; Aiello Lloyd Paul
Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(1):76-8.
2002: Zerbini Cristiano A F; Anderson Jennifer J; Kane Kelly A; Ju Shyr-Te; Campistol Jose M; Simms Robert W; Cohen Alan S; Skinner Martha
Beta 2 microglobulin serum levels and prediction of survival in AL amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2002;9(4):242-6.
2002: Xiao Sheng; Jodo Satoshi; Sung Sun-Sang J; Marshak-Rothstein Ann; Ju Shyr-Te
A novel signaling mechanism for soluble CD95 ligand. Synergy with anti-CD95 monoclonal antibodies for apoptosis and NF-kappaB nuclear translocation.
The Journal of biological chemistry 2002;277(52):50907-13.
2001: Hohlbaum A M; Gregory M S; Ju S T; Marshak-Rothstein A
Fas ligand engagement of resident peritoneal macrophages in vivo induces apoptosis and the production of neutrophil chemotactic factors.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6217-24.
2001: Xiao S; Marshak-Rothstein A; Ju S T
Sp1 is the major fasl gene activator in abnormal CD4(-)CD8(-)B220(+) T cells of lpr and gld mice.
European journal of immunology 2001;31(11):3339-48.
2001: Jodo S; Xiao S; Hohlbaum A; Strehlow D; Marshak-Rothstein A; Ju S T
Apoptosis-inducing membrane vesicles. A novel agent with unique properties.
The Journal of biological chemistry 2001;276(43):39938-44.
2000: Jodo S; Hohlbaum A M; Xiao S; Chan D; Strehlow D; Sherr D H; Marshak-Rothstein A; Ju S T
CD95 (Fas) ligand-expressing vesicles display antibody-mediated, FcR-dependent enhancement of cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5487-94.
2000: Jodo S; Strehlow D; Ju S T
Bioactivities of Fas ligand-expressing retroviral particles.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(10):5062-9.
2000: Strehlow D; Jodo S; Ju S T
Retroviral membrane display of apoptotic effector molecules.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4209-14.
2000: Wang J K; Ju S T; Marshak-Rothstein A
Protection of T cells from activation-induced cell death by Fas+ B cells.
European journal of immunology 2000;30(3):931-7.
2000: Matsui K; Xiao S; Fine A; Ju S T
Role of activator protein-1 in TCR-mediated regulation of the murine fasl promoter.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):3002-8.
1999: Xiao S; Matsui K; Fine A; Zhu B; Marshak-Rothstein A; Widom R L; Ju S T
FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3.
European journal of immunology 1999;29(11):3456-65.
1999: Matsui K; Jodo S; Xiao S; Ju S T
Hypothesis: A recurrent, moderate activation fosters systemic autoimmunity--the apoptotic roles of TCR, IL-2 and Fas ligand.
Journal of biomedical science 1999;6(5):306-13.
1999: Ju S T; Matsui K; Ozdemirli M
Molecular and cellular mechanisms regulating T and B cell apoptosis through Fas/FasL interaction.
International reviews of immunology 1999;18(5-6):485-513.
1998: Rifkin I R; Channavajhala P L; Kiefer H L; Carmack A J; Landesman-Bollag E; Beaudette B C; Jersky B; Salant D J; Ju S T; Marshak-Rothstein A; Seldin D C
Acceleration of lpr lymphoproliferative and autoimmune disease by transgenic protein kinase CK2 alpha.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5164-70.
1998: Matsui K; Fine A; Zhu B; Marshak-Rothstein A; Ju S T
Identification of two NF-kappa B sites in mouse CD95 ligand (Fas ligand) promoter: functional analysis in T cell hybridoma.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3469-73.
1998: Kung J T; Beller D; Ju S T
Lymphokine regulation of activation-induced apoptosis in T cells of IL-2 and IL-2R beta knockout mice.
Cellular immunology 1998;185(2):158-63.
1997: Matsui K; Omura S; Cui H; Schauer S L; Sonenshein G E; Ju S T
Proteasome regulation of Fas ligand cytotoxicity.
European journal of immunology 1997;27(9):2269-78.
1997: Wang J K; Zhu B; Ju S T; Tschopp J; Marshak-Rothstein A
CD4+ T cells reactivated with superantigen are both more sensitive to FasL-mediated killing and express a higher level of FasL.
Cellular immunology 1997;179(2):153-64.
1997: Cui H; Matsui K; Omura S; Schauer S L; Matulka R A; Sonenshein G E; Ju S T
Proteasome regulation of activation-induced T cell death.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7515-20.
1997: Jacobson B A; Foote L C; Panka D J; Ju S T; Rothstein T L; Marshak-Rothstein A
Unique site of autoantibody production in Fas-deficient mice.
Annals of the New York Academy of Sciences 1997;815():218-29.
1996: Cui H; Ju S T; Sherr D H
Functional expression of Fas (CD95) protein in autoimmune lpr mice.
Cellular immunology 1996;174(1):35-41.
1996: Foote L C; Schneider T J; Fischer G M; Wang J K; Rasmussen B; Campbell K A; Lynch D H; Ju S T; Marshak-Rothstein A; Rothstein T L
Intracellular signaling for inducible antigen receptor-mediated Fas resistance in B cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(5):1878-85.
1996: Yamaguchi K; Near R; Shneider A; Cui H; Ju S T; Sherr D H
Fluoranthene-induced apoptosis in murine T cell hybridomas is independent of the aromatic hydrocarbon receptor.
Toxicology and applied pharmacology 1996;139(1):144-52.
1996: Ozdemirli M; El-Khatib M; Foote L C; Wang J K; Marshak-Rothstein A; Rothstein T L; Ju S T
Fas (CD95)/Fas ligand interactions regulate antigen-specific, major histocompatibility complex-restricted T/B cell proliferative responses.
European journal of immunology 1996;26(2):415-9.
1996: Cui H; el-Khatib M; Sherr D H; Ettinger R; Sy M S; Marshak-Rothstein A; Ju S T
Characterization of lpr-derived T cell hybridomas: Fas-deficient hybridomas are deathless, growth-arrested, and cytotoxic upon activation.
Cellular immunology 1996;167(2):302-12.
1996: Cui H; Sherr D H; el-Khatib M; Matsui K; Panka D J; Marshak-Rothstein A; Ju S T
Regulation of T-cell death genes: selective inhibition of FasL- but not Fas-mediated function.
Cellular immunology 1996;167(2):276-84.
1996: Rothstein T L; Foote L C; Schneider T J; Fischer G M; Jacobson B A; Lynch D H; Ju S T; Marshak-Rothstein A
Inducible resistance to Fas-mediated apoptosis in primary B lymphocytes.
Advances in experimental medicine and biology 1996;406():177-89.
1995: el-Khatib M; Stanger B Z; Dogan H; Cui H; Ju S T
The molecular mechanism of FasL-mediated cytotoxicity by CD4+ Th1 clones.
Cellular immunology 1995;163(2):237-44.
1995: Ettinger R; Panka D J; Wang J K; Stanger B Z; Ju S T; Marshak-Rothstein A
Fas ligand-mediated cytotoxicity is directly responsible for apoptosis of normal CD4+ T cells responding to a bacterial superantigen.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(9):4302-8.
1995: Rothstein T L; Wang J K; Panka D J; Foote L C; Wang Z; Stanger B; Cui H; Ju S T; Marshak-Rothstein A
Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.
Nature 1995;374(6518):163-5.
1995: Ju S T; Panka D J; Cui H; Ettinger R; el-Khatib M; Sherr D H; Stanger B Z; Marshak-Rothstein A
Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.
Nature 1995;373(6513):444-8.
1994: Ju S T; Cui H; Panka D J; Ettinger R; Marshak-Rothstein A
Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4185-9.
1993: Ju S T; Nonogaki T; Bernatowicz M S; Matsueda G R
The B cell immune response to an idiotype-inducing peptide epitope can be inhibited by immunodominance of a neighboring epitope.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(7):2641-7.
1992: Ozdemirli M; el-Khatib M; Bastiani L; Akdeniz H; Kuchroo V; Ju S T
The cytotoxic process of CD4 Th1 clones.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(6):1889-95.
1991: Ozdemirli M; Akdeniz H; el-Khatib M; Ju S T
A novel cytotoxicity of CD4+ Th1 clones on heat-shocked tumor targets. I. Implications for internal disintegration model for target death and hyperthermia treatment of cancers.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):4027-34.
1991: Ju S T
Distinct pathways of CD4 and CD8 cells induce rapid target DNA fragmentation.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(3):812-8.
1990: Shirahama T; Miura K; Ju S T; Kisilevsky R; Gruys E; Cohen A S
Amyloid enhancing factor-loaded macrophages in amyloid fibril formation.
Laboratory investigation; a journal of technical methods and pathology 1990;62(1):61-8.
1990: Miura K; Ju S T; Cohen A S; Shirahama T
Generation and use of site-specific antibodies to serum amyloid A for probing amyloid A development.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(2):610-3.
1990: Strack P; Martin C; Saito S; Dekruyff R H; Ju S T
Metabolic inhibitors distinguish cytolytic activity of CD4 and CD8 clones.
European journal of immunology 1990;20(1):179-84.
1990: Ju S T; Ruddle N H; Strack P; Dorf M E; DeKruyff R H
Expression of two distinct cytolytic mechanisms among murine CD4 subsets.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(1):23-31.
1989: Ju S T; Strack P; Dorf M E
Production and immunoselection of IgM-IgA hybridomas: preparing immunoglobulins with dual binding specificity.
Molecular immunology 1989;26(3):283-92.
1988: Ju S T; Strack P; Stromquist D; Dekruyff R H
Cytolytic activity of Ia-restricted T cell clones and hybridomas: evidence for a cytolytic mechanism independent of interferon-gamma, lymphotoxin, and tumor necrosis factor-alpha.
Cellular immunology 1988;117(2):399-413.

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Shyr-Te Ju

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