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Andreas Jung
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Research Profile (preview)
Disorders
Chemicals & Drugs
Procedures
Physiology
Anatomy
Genes & Molecular Sequences
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Network (preview)
41
Kirchner, Thomas
35
Brabletz, Thomas
18
Hlubek, Falk
9
Spaderna, Simone
7
Hohenberger, Werner
7
Brueckl, Wolfgang
6
Niedobitek, Gerald
6
Wein, Axel
6
Hahn, Eckhart
5
Hiendlmeyer, Elke
5
Faller, Gerhard
4
Haynl, Angela
4
Meru, Nadine
4
Schmalhofer, Otto
3
Ruckert, Stefan
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Geonetwork of Andreas Jung (preview)
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All Publications
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2009: Horst David; Scheel Silvio K; Liebmann Sibylle; Neumann Jens; Maatz Susanne; Kirchner Thomas; Jung Andreas
The cancer stem cell marker CD133 has high prognostic impact but unknown functional relevance for the metastasis of human colon cancer.
The Journal of pathology 2009;219(4):427-34.
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2009: Horst David; Kriegl Lydia; Engel Jutta; Kirchner Thomas; Jung Andreas
Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer.
Cancer investigation 2009;27(8):844-50.
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2009: Herbst Andreas; Bommer Guido T; Kriegl Lydia; Jung Andreas; Behrens Andrea; Csanadi Endy; Gerhard Markus; Bolz Christian; Riesenberg Rainer; Zimmermann Wolfgang; Dietmaier Wolfgang; Wolf Isabella; Brabletz Thomas; Göke Burkhard; Kolligs Frank T
ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition.
Gastroenterology 2009;137(2):639-48, 648.e1-9.
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2009: Horst David; Kriegl Lydia; Engel Jutta; Jung Andreas; Kirchner Thomas
CD133 and nuclear beta-catenin: the marker combination to detect high risk cases of low stage colorectal cancer.
European journal of cancer (Oxford, England : 1990) 2009;45(11):2034-40.
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2009: Horst David; Reu Simone; Kriegl Lydia; Engel Jutta; Kirchner Thomas; Jung Andreas
The intratumoral distribution of nuclear beta-catenin is a prognostic marker in colon cancer.
Cancer 2009;115(10):2063-70.
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2009: Heinemann Volker; Stintzing Sebastian; Kirchner Thomas; Boeck Stefan; Jung Andreas
Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR.
Cancer treatment reviews 2009;35(3):262-71.
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2009: Baehs Sebastian; Herbst Andreas; Thieme Susanne E; Perschl Claudia; Behrens Andrea; Scheel Silvio; Jung Andreas; Brabletz Thomas; Göke Burkhard; Blum Helmut; Kolligs Frank T
Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells.
Cancer letters 2009;276(2):152-9.
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2009: Wassermann Stella; Scheel Silvio K; Hiendlmeyer Elke; Palmqvist Richard; Horst David; Hlubek Falk; Haynl Angela; Kriegl Lydia; Reu Simone; Merkel Susanne; Brabletz Thomas; Kirchner Thomas; Jung Andreas
p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors.
Gastroenterology 2009;136(1):196-205.e2.
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2008: Horst D; Kriegl L; Engel J; Kirchner T; Jung A
CD133 expression is an independent prognostic marker for low survival in colorectal cancer.
British journal of cancer 2008;99(8):1285-9.
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2008: De Toni Enrico N; Thieme Susanne E; Herbst Andreas; Behrens Andrea; Stieber Petra; Jung Andreas; Blum Helmut; Göke Burkhard; Kolligs Frank T
OPG is regulated by beta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4713-8.
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2008: Spaderna Simone; Schmalhofer Otto; Wahlbuhl Mandy; Dimmler Arno; Bauer Katja; Sultan Aneesa; Hlubek Falk; Jung Andreas; Strand Dennis; Eger Andreas; Kirchner Thomas; Behrens Jürgen; Brabletz Thomas
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer.
Cancer research 2008;68(2):537-44.
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2008: Müller-Höcker J; Babaryka G; Schmid I; Jung A
Overexpression of cyclin D1, D3, and p21 in an infantile renal carcinoma with Xp11.2 TFE3-gene fusion.
Pathology, research and practice 2008;204(8):589-97.
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2007: Hlubek Falk; Brabletz Thomas; Budczies Jan; Pfeiffer Sabine; Jung Andreas; Kirchner Thomas
Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer.
International journal of cancer. Journal international du cancer 2007;121(9):1941-8.
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2007: Hlubek Falk; Spaderna Simone; Schmalhofer Otto; Jung Andreas; Kirchner Thomas; Brabletz Thomas
Wnt/FZD signaling and colorectal cancer morphogenesis.
Frontiers in bioscience : a journal and virtual library 2007;12():458-70.
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2006: Hornung Veit; Ellegast Jana; Kim Sarah; Brzózka Krzysztof; Jung Andreas; Kato Hiroki; Poeck Hendrik; Akira Shizuo; Conzelmann Karl-Klaus; Schlee Martin; Endres Stefan; Hartmann Gunther
5'-Triphosphate RNA is the ligand for RIG-I.
Science (New York, N.Y.) 2006;314(5801):994-7.
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2006: Spaderna Simone; Schmalhofer Otto; Hlubek Falk; Berx Geert; Eger Andreas; Merkel Susanne; Jung Andreas; Kirchner Thomas; Brabletz Thomas
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer.
Gastroenterology 2006;131(3):830-40.
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2006: Hlubek F; Pfeiffer S; Budczies J; Spaderna S; Jung A; Kirchner T; Brabletz T
Securin (hPTTG1) expression is regulated by beta-catenin/TCF in human colorectal carcinoma.
British journal of cancer 2006;94(11):1672-7.
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2005: Beiter Katharina; Hiendlmeyer Elke; Brabletz Thomas; Hlubek Falk; Haynl Angela; Knoll Claudia; Kirchner Thomas; Jung Andreas
beta-Catenin regulates the expression of tenascin-C in human colorectal tumors.
Oncogene 2005;24(55):8200-4.
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2005: Brabletz Thomas; Jung Andreas; Spaderna Simone; Hlubek Falk; Kirchner Thomas
Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression.
Nature reviews. Cancer 2005;5(9):744-9.
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2005: Brueckl Wolfgang M; Grombach Jens; Wein Axel; Ruckert Stefan; Porzner Marc; Dietmaier Wolfgang; Rümmele Petra; Croner Roland S; Boxberger Frank; Kirchner Thomas; Hohenberger Werner; Hahn Eckhart G; Jung Andreas
Alterations in the tissue inhibitor of metalloproteinase-3 (TIMP-3) are found frequently in human colorectal tumours displaying either microsatellite stability (MSS) or instability (MSI).
Cancer letters 2005;223(1):137-42.
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2005: Stintzing Sebastian; Heuschmann Peter; Barbera Letterio; Ocker Matthias; Jung Andreas; Kirchner Thomas; Neureiter Daniel
Overexpression of MMP9 and tissue factor in unstable carotid plaques associated with Chlamydia pneumoniae, inflammation, and apoptosis.
Annals of vascular surgery 2005;19(3):310-9.
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2005: Brabletz Thomas; Hlubek Falk; Spaderna Simone; Schmalhofer Otto; Hiendlmeyer Elke; Jung Andreas; Kirchner Thomas
Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and beta-catenin.
Cells, tissues, organs 2005;179(1-2):56-65.
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2004: Brabletz Thomas; Spaderna Simone; Kolb Jochen; Hlubek Falk; Faller Gerhard; Bruns Christiane J; Jung Andreas; Nentwich Jens; Duluc Isabelle; Domon-Dell Claire; Kirchner Thomas; Freund Jean-Noel
Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression.
Cancer research 2004;64(19):6973-7.
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2004: Faller Gerhard; Dimmler Arno; Rau Tilman; Spaderna Simone; Hlubek Falk; Jung Andreas; Kirchner Thomas; Brabletz Thomas
Evidence for acid-induced loss of Cdx2 expression in duodenal gastric metaplasia.
The Journal of pathology 2004;203(4):904-8.
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2004: Hiendlmeyer Elke; Regus Susanne; Wassermann Stella; Hlubek Falk; Haynl Angela; Dimmler Arno; Koch Claudia; Knoll Claudia; van Beest Moniek; Reuning Ute; Brabletz Thomas; Kirchner Thomas; Jung Andreas
Beta-catenin up-regulates the expression of the urokinase plasminogen activator in human colorectal tumors.
Cancer research 2004;64(4):1209-14.
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2004: Brueckl Wolfgang M; Heinze Elvira; Milsmann Catrin; Wein Axel; Koebnick Corinna; Jung Andreas; Croner Roland S; Brabletz Thomas; Günther Klaus; Kirchner Thomas; Hahn Eckhart G; Hohenberger Werner; Becker Heinz; Reingruber Bertram
Prognostic significance of microsatellite instability in curatively resected adenocarcinoma of the small intestine.
Cancer letters 2004;203(2):181-90.
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2004: Riese J; Niedobitek G; Lisner R; Jung A; Hohenberger W; Haupt W
Expression of interleukin-6 and monocyte chemoattractant protein-1 by peritoneal sub-mesothelial cells during abdominal operations.
The Journal of pathology 2004;202(1):34-40.
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2004: Hlubek Falk; Spaderna Simone; Jung Andreas; Kirchner Thomas; Brabletz Thomas
Beta-catenin activates a coordinated expression of the proinvasive factors laminin-5 gamma2 chain and MT1-MMP in colorectal carcinomas.
International journal of cancer. Journal international du cancer 2004;108(2):321-6.
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2003: Neureiter Daniel; Heuschmann Peter; Stintzing Sebastian; Kolominsky-Rabas Peter; Barbera Letterio; Jung Andreas; Ocker Matthias; Maass Matthias; Faller Gerhard; Kirchner Thomas
Detection of Chlamydia pneumoniae but not of Helicobacter pylori in symptomatic atherosclerotic carotids associated with enhanced serum antibodies, inflammation and apoptosis rate.
Atherosclerosis 2003;168(1):153-62.
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2003: Brueckl W M; Moesch C; Brabletz T; Koebnick C; Riedel C; Jung A; Merkel S; Schaber S; Boxberger F; Kirchner T; Hohenberger W; Hahn E G; Wein A
Relationship between microsatellite instability, response and survival in palliative patients with colorectal cancer undergoing first-line chemotherapy.
Anticancer research 2003;23(2C):1773-7.
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2002: Reiche Nicole; Jung Andreas; Brabletz Thomas; Vater Tanja; Kirchner Thomas; Faller Gerhard
Generation and characterization of human monoclonal scFv antibodies against Helicobacter pylori antigens.
Infection and immunity 2002;70(8):4158-64.
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2002: Brabletz Thomas; Jung Andreas; Kirchner Thomas
Beta-catenin and the morphogenesis of colorectal cancer.
Virchows Archiv : an international journal of pathology 2002;441(1):1-11.
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2002: Ruckert Stefan; Hiendlmeyer Elke; Brueckl Wolfgang M; Oswald Ursula; Beyser Kurt; Dietmaier Wolfgang; Haynl Angela; Koch Claudia; Rüschoff Josef; Brabletz Thomas; Kirchner Thomas; Jung Andreas
T-cell factor-4 frameshift mutations occur frequently in human microsatellite instability-high colorectal carcinomas but do not contribute to carcinogenesis.
Cancer research 2002;62(11):3009-13.
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2002: Jung A; Ruckert S; Frank P; Brabletz T; Kirchner T
7-Deaza-2'-deoxyguanosine allows PCR and sequencing reactions from CpG islands.
Molecular pathology : MP 2002;55(1):55-7.
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2002: Meru Nadine; Jung Andreas; Baumann Irith; Niedobitek Gerald
Expression of the recombination-activating genes in extrafollicular lymphocytes but no apparent reinduction in germinal center reactions in human tonsils.
Blood 2002;99(2):531-7.
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2001: Hlubek F; Jung A; Kotzor N; Kirchner T; Brabletz T
Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin.
Cancer research 2001;61(22):8089-93.
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2001: Jung A; Schrauder M; Oswald U; Knoll C; Sellberg P; Palmqvist R; Niedobitek G; Brabletz T; Kirchner T
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation.
The American journal of pathology 2001;159(5):1613-7.
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2001: Kirchner T; Müller S; Hattori T; Mukaisyo K; Papadopoulos T; Brabletz T; Jung A
Metaplasia, intraepithelial neoplasia and early cancer of the stomach are related to dedifferentiated epithelial cells defined by cytokeratin-7 expression in gastritis.
Virchows Archiv : an international journal of pathology 2001;439(4):512-22.
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2001: Brueckl W M; Preuss J M; Wein A; Jung A; Brabletz T; Pflüger R; Wiest G H; Wolfl C; Kirchner T; Hahn E G; Hohenberger W; Günther K
Ki-67 expression and residual tumour (R) classification are associated with disease-free survival in desmoid tumour patients.
Anticancer research 2001;21(5):3615-20.
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2001: Brabletz T; Jung A; Reu S; Porzner M; Hlubek F; Kunz-Schughart L A; Knuechel R; Kirchner T
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10356-61.
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2001: Meru N; Davison S; Whitehead L; Jung A; Mutimer D; Rooney N; Kelly D; Niedobitek G
Epstein-Barr virus infection in paediatric liver transplant recipients: detection of the virus in post-transplant tonsillectomy specimens.
Molecular pathology : MP 2001;54(4):264-9.
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2001: Meru N; Jung A; Lisner R; Niedobitek G
Expression of the recombination activating genes (RAG1 and RAG2) is not detectable in Epstein-Barr virus-associated human lymphomas.
International journal of cancer. Journal international du cancer 2001;92(1):75-8.
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2001: Hlubek F; Löhberg C; Meiler J; Jung A; Kirchner T; Brabletz T
Tip60 is a cell-type-specific transcriptional regulator.
Journal of biochemistry 2001;129(4):635-41.
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2001: Hauptmann S; Meru N; Schewe C; Jung A; Hiepe F; Burmester G; Niedobitek G; Buttgereit F
Fatal atypical T-cell proliferation associated with Epstein-Barr virus infection.
British journal of haematology 2001;112(2):377-80.
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2000: Brueckl W M; Limmert T; Brabletz T; Guenther K; Jung A; Hermann K; Wiest G H; Kirchner T; Hohenberger W; Hahn E G; Wein A
Mismatch repair deficiency in sporadic synchronous colorectal cancer.
Anticancer research 2000;20(6C):4727-32.
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2000: Brueckl W M; Jung A; Wein A; Brabletz T; Guenther K; Nusko G; Hahn E G
Microsatellite instability in colorectal adenomas: relevance and clinical importance.
International journal of colorectal disease 2000;15(4):189-96.
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2000: Brabletz T; Herrmann K; Jung A; Faller G; Kirchner T
Expression of nuclear beta-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas.
The American journal of pathology 2000;156(3):865-70.
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2000: Brabletz T; Jung A; Dag S; Reu S; Kirchner T
[beta-Catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma]
Verhandlungen der Deutschen Gesellschaft für Pathologie 2000;84():175-81.
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1999: Brabletz T; Jung A; Dag S; Hlubek F; Kirchner T
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer.
The American journal of pathology 1999;155(4):1033-8.
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1999: Brabletz T; Jung A; Hlubek F; Löhberg C; Meiler J; Suchy U; Kirchner T
Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB.
International immunology 1999;11(10):1701-8.
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1998: Steininger H; Faller G; Dewald E; Brabletz T; Jung A; Kirchner T
Apoptosis in chronic gastritis and its correlation with antigastric autoantibodies.
Virchows Archiv : an international journal of pathology 1998;433(1):13-8.
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1998: Brabletz T; Jung A; Hermann K; Günther K; Hohenberger W; Kirchner T
Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front.
Pathology, research and practice 1998;194(10):701-4.
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