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Wolfgang Junger

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Wolfgang G Junger; Linglin Li; Shawn G Rhind; Sandro B Rizoli; Pang N Shek; Maria Y Shiu; Andrew J Baker; Joseph Cuschieri; David B Hoyt; Eileen M Bulger
Resuscitation of traumatic hemorrhagic shock patients with hypertonic saline-without dextran-inhibits neutrophil and endothelial cell activation.
Yu Chen; Wolfgang G Junger
Measurement of oxidative burst in neutrophils.
Yoshiaki Inoue; Hiroshi Tanaka; Yuka Sumi; Tobias Woehrle; Yu Chen; Mark I Hirsh; Wolfgang G Junger
A3 adenosine receptor inhibition improves the efficacy of hypertonic saline resuscitation.

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2012: Wolfgang G Junger; Linglin Li; Shawn G Rhind; Sandro B Rizoli; Pang N Shek; Maria Y Shiu; Andrew J Baker; Joseph Cuschieri; David B Hoyt; Eileen M Bulger
Resuscitation of traumatic hemorrhagic shock patients with hypertonic saline-without dextran-inhibits neutrophil and endothelial cell activation.
Shock (Augusta, Ga.) 2012;38(4):341-50.
2012: Yu Chen; Wolfgang G Junger
Measurement of oxidative burst in neutrophils.
Methods in molecular biology (Clifton, N.J.) 2012;844():115-24.
2011: Yoshiaki Inoue; Hiroshi Tanaka; Yuka Sumi; Tobias Woehrle; Yu Chen; Mark I Hirsh; Wolfgang G Junger
A3 adenosine receptor inhibition improves the efficacy of hypertonic saline resuscitation.
Shock (Augusta, Ga.) 2011;35(2):178-83.
2010: Tobias Woehrle; Linda Yip; Abdallah Elkhal; Yuka Sumi; Yu Chen; Yongli Yao; Paul A Insel; Wolfgang G Junger
Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse.
Blood 2010;116(18):3475-84.
2009: Linda Yip; Tobias Woehrle; Ross Corriden; Mark Hirsh; Yu Chen; Yoshiaki Inoue; Vhe Ferrari; Paul Insel; Wolfgang G Junger
Autocrine regulation of T-cell activation by ATP release and P2X7 receptors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(6):1685-93.
2008: Mark I Hirsh; Wolfgang G Junger
Roles of heat shock proteins and gamma delta T cells in inflammation.
American journal of respiratory cell and molecular biology 2008;39(5):509-13.
2008: Ross Corriden; Yu Chen; Yoshiaki Inoue; Guido Beldi; Simon C Robson; Paul Insel; Wolfgang G Junger
Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine.
The Journal of biological chemistry 2008;283(42):28480-6.
2008: Yoshiaki Inoue; Yu Chen; Reinhard Pauzenberger; Mark I Hirsh; Wolfgang G Junger
Hypertonic saline up-regulates A3 adenosine receptor expression of activated neutrophils and increases acute lung injury after sepsis.
Critical care medicine 2008;36(9):2569-75.
2008: Yoshiaki Inoue; Yu Chen; Mark I Hirsh; Linda Yip; Wolfgang G Junger
A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis.
Shock (Augusta, Ga.) 2008;30(2):173-7.
2007: Ross Corriden; Paul Insel; Wolfgang G Junger
A novel method using fluorescence microscopy for real-time assessment of ATP release from individual cells.
American journal of physiology. Cell physiology 2007;293(4):C1420-5.
2007: Linda Yip; Cindy W Cheung; Ross Corriden; Yu Chen; Paul Insel; Wolfgang G Junger
Hypertonic stress regulates T-cell function by the opposing actions of extracellular adenosine triphosphate and adenosine.
Shock (Augusta, Ga.) 2007;27(3):242-50.
2007: Naoyuki Hashiguchi; Linda Lum; Elizabeth Romeril; Yu Chen; Linda Yip; David B Hoyt; Wolfgang G Junger
Hypertonic saline resuscitation: efficacy may require early treatment in severely injured patients.
The Journal of trauma 2007;62(2):299-306.
2006: Yu Chen; Ross Corriden; Yoshiaki Inoue; Linda Yip; Naoyuki Hashiguchi; Annelies Zinkernagel; Victor Nizet; Paul Insel; Wolfgang G Junger
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors.
Science (New York, N.Y.) 2006;314(5806):1792-5.
2006: Yu Chen; Naoyuki Hashiguchi; Linda Yip; Wolfgang G Junger
Hypertonic saline enhances neutrophil elastase release through activation of P2 and A3 receptors.
American journal of physiology. Cell physiology 2006;290(4):C1051-9.
2006: Mark Hirsh; Naoyuki Hashiguchi; Yu Chen; Linda Yip; Wolfgang G Junger
Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.
European journal of immunology 2006;36(3):712-21.
2004: Yu Chen; Alok Shukla; Sachiko Namiki; Paul Insel; Wolfgang G Junger
A putative osmoreceptor system that controls neutrophil function through the release of ATP, its conversion to adenosine, and activation of A2 adenosine and P2 receptors.
Journal of leukocyte biology 2004;76(1):245-53.
2004: Alok Shukla; Naoyuki Hashiguchi; Yu Chen; Raul Coimbra; David B Hoyt; Wolfgang G Junger
Osmotic regulation of cell function and possible clinical applications.
Shock (Augusta, Ga.) 2004;21(5):391-400.
2004: Jay J Doucet; David B Hoyt; Raul Coimbra; Geert W Schmid-Schönbein; Wolfgang G Junger; Wolf Paul L; William H Loomis; Tony E Hugli
Inhibition of enteral enzymes by enteroclysis with nafamostat mesilate reduces neutrophil activation and transfusion requirements after hemorrhagic shock.
The Journal of trauma 2004;56(3):501-10; discussion 510-1.
2003: Yoshinori Murao; William H Loomis; Paul Wolf; David B Hoyt; Wolfgang G Junger
Effect of dose of hypertonic saline on its potential to prevent lung tissue damage in a mouse model of hemorrhagic shock.
Shock (Augusta, Ga.) 2003;20(1):29-34.
2003: Yoshinori Murao; Michiaki Hata; Ken Ohnishi; Kazuo Okuchi; Yoshiyuki Nakajima; Yoshio Hiasa; Wolfgang G Junger; David B Hoyt; Takeo Ohnishi
Hypertonic saline resuscitation reduces apoptosis and tissue damage of the small intestine in a mouse model of hemorrhagic shock.
Shock (Augusta, Ga.) 2003;20(1):23-8.
2003: William H Loomis; Sachiko Namiki; Rennolds S Ostrom; Paul Insel; Wolfgang G Junger
Hypertonic stress increases T cell interleukin-2 expression through a mechanism that involves ATP release, P2 receptor, and p38 MAPK activation.
The Journal of biological chemistry 2003;278(7):4590-6.
2003: Heidi Junger; David B. Edelman; Wolfgang G Junger
Hypertonicity promotes survival of corticospinal motoneurons via mitogen-activated protein kinase p38 signaling.
Journal of molecular neuroscience : MN 2003;21(2):111-20.
2002: Tatjana Orlic; William H Loomis; Amy Shreve; Sachiko Namiki; Wolfgang G Junger
Hypertonicity increases cAMP in PMN and blocks oxidative burst by PKA-dependent and -independent mechanisms.
American journal of physiology. Cell physiology 2002;282(6):C1261-9.
2001: William H Loomis; Sachiko Namiki; David B Hoyt; Wolfgang G Junger
Hypertonicity rescues T cells from suppression by trauma-induced anti-inflammatory mediators.
American journal of physiology. Cell physiology 2001;281(3):C840-8.
2000: Niren Angle; R Cabello-Passini; David B Hoyt; William H Loomis; A Shreve; Sachiko Namiki; Wolfgang G Junger
Hypertonic saline infusion: can it regulate human neutrophil function?
Shock (Augusta, Ga.) 2000;14(5):503-8.
2000: Yoshinori Murao; David B Hoyt; William H Loomis; Sachiko Namiki; N Patel; P Wolf; Wolfgang G Junger
Does the timing of hypertonic saline resuscitation affect its potential to prevent lung damage?
Shock (Augusta, Ga.) 2000;14(1):18-23.
1998: Heidi Junger; Wolfgang G Junger
CNTF and GDNF, but not NT-4, support corticospinal motor neuron growth via direct mechanisms.
Neuroreport 1998;9(16):3749-54.
1998: J Hutter; Wolfgang G Junger; K Miller; E Moritz
Subxiphoidal videomediastinoscopy for diagnostic access to the anterior mediastinum.
The Annals of thoracic surgery 1998;66(4):1427-8.
1998: Niren Angle; David B Hoyt; R Cabello-Passini; C Herdon-Remelius; William H Loomis; Wolfgang G Junger
Hypertonic saline resuscitation reduces neutrophil margination by suppressing neutrophil L selectin expression.
The Journal of trauma 1998;45(1):7-12; discussion 12-3.
1998: Wolfgang G Junger; David B Hoyt; R E Davis; C Herdon-Remelius; Sachiko Namiki; Heidi Junger; William H Loomis; A Altman
Hypertonicity regulates the function of human neutrophils by modulating chemoattractant receptor signaling and activating mitogen-activated protein kinase p38.
The Journal of clinical investigation 1998;101(12):2768-79.
1998: Niren Angle; David B Hoyt; Raul Coimbra; F Liu; C Herdon-Remelius; William H Loomis; Wolfgang G Junger
Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock.
Shock (Augusta, Ga.) 1998;9(3):164-70.
1997: Wolfgang G Junger; W G Junger; J Hutter; K Miller; E Moritz
Delayed diagnosis of malignant tumors missed at laparoscopic cholecystectomy.
Surgical endoscopy 1997;11(10):1010-2.
1997: W G Junger; Raul Coimbra; F C Liu; C Herdon-Remelius; Wolfgang G Junger; Heidi Junger; William H Loomis; David B Hoyt; A Altman
Hypertonic saline resuscitation: a tool to modulate immune function in trauma patients?
Shock (Augusta, Ga.) 1997;8(4):235-41.
1997: K Miller; Wolfgang G Junger
Ileocutaneous fistula formation following laparoscopic polypropylene mesh hernia repair.
Surgical endoscopy 1997;11(7):772-3.
1997: Raul Coimbra; David B Hoyt; Wolfgang G Junger; Niren Angle; P Wolf; William H Loomis; M F Evers
Hypertonic saline resuscitation decreases susceptibility to sepsis after hemorrhagic shock.
The Journal of trauma 1997;42(4):602-6; discussion 606-7.
1997: W G Junger; David B Hoyt; M Hamreus; F C Liu; C Herdon-Remelius; Wolfgang G Junger; A Altman
Hypertonic saline activates protein tyrosine kinases and mitogen-activated protein kinase p38 in T-cells.
The Journal of trauma 1997;42(3):437-43; discussion 443-5.
1996: W Junger; Wolfgang G Junger; K Miller; Soheyl Bahrami; Heinz Redl; G Schlag; E Moritz
Early detection of anastomotic leaks after colorectal surgery by measuring endotoxin in the drainage fluid.
Hepato-gastroenterology 1996;43(12):1523-9.
1996: F C Liu; David B Hoyt; Raul Coimbra; Wolfgang G Junger
Proliferation assays with human, rabbit, rat, and mouse lymphocytes.
In vitro cellular & developmental biology. Animal 1996;32(9):520-3.
1996: Raul Coimbra; Wolfgang G Junger; David B Hoyt; F C Liu; W H Loomis; M F Evers
Hypertonic saline resuscitation restores hemorrhage-induced immunosuppression by decreasing prostaglandin E2 and interleukin-4 production.
The Journal of surgical research 1996;64(2):203-9.
1996: R K Simons; Wolfgang G Junger; W H Loomis; David B Hoyt
Acute lung injury in endotoxemic rats is associated with sustained circulating IL-6 levels and intrapulmonary CINC activity and neutrophil recruitment--role of circulating TNF-alpha and IL-beta?
Shock (Augusta, Ga.) 1996;6(1):39-45.
1996: Wolfgang G Junger; David B Hoyt; F C Liu; W H Loomis; Raul Coimbra
Immunosuppression after endotoxin shock: the result of multiple anti-inflammatory factors.
The Journal of trauma 1996;40(5):702-9.
1995: Raul Coimbra; Wolfgang G Junger; F C Liu; W H Loomis; David B Hoyt
Hypertonic/hyperoncotic fluids reverse prostaglandin E2 (PGE2)-induced T-cell suppression.
Shock (Augusta, Ga.) 1995;4(1):45-9.
1995: Wolfgang G Junger; David B Hoyt; H Redl; F C Liu; W H Loomis; J Davies; G Schlag
Tumor necrosis factor antibody treatment of septic baboons reduces the production of sustained T-cell suppressive factors.
Shock (Augusta, Ga.) 1995;3(3):173-8.
1995: Wolfgang G Junger; J Hutter; K Miller; E Moritz
Significance of preoperative colonoscopy in laparoscopic cholecystectomy.
Endoscopy 1995;27(1):138-9.
1994: David B Hoyt; Wolfgang G Junger; W H Loomis; F C Liu
Effects of trauma on immune cell function: impairment of intracellular calcium signaling.
Shock (Augusta, Ga.) 1994;2(1):23-8.
1994: Wolfgang G Junger; F C Liu; W H Loomis; David B Hoyt
Hypertonic saline enhances cellular immune function.
Circulatory shock 1994;42(4):190-6.
1994: Wolfgang G Junger; F C Liu; W B Loomis; David B Hoyt
Hypertonic saline solution as disinfectant.
East African medical journal 1994;71(2):83.
1993: K Miller; N Hölbling; J Hutter; Wolfgang G Junger; E Moritz; T Speil
Laparoscopic cholecystectomy for patients who have had previous abdominal surgery.
Surgical endoscopy 1993;7(5):400-3.
1993: Wolfgang G Junger; T A Cardoza; F C Liu; David B Hoyt; R Goodwin
Improved rapid photometric assay for quantitative measurement of PMN migration.
Journal of immunological methods 1993;160(1):73-9.
1992: Wolfgang G Junger; S Hallström; F C Liu; H Redl; G Schlag
The enzymatic and release characteristics of sheep neutrophil elastase: a comparison with human neutrophil elastase.
Biological chemistry Hoppe-Seyler 1992;373(8):691-8.
1992: Wolfgang G Junger; S Hallström; H Redl; G Schlag
Inhibition of human, ovine, and baboon neutrophil elastase with Eglin c and secretory leukocyte proteinase inhibitor.
Biological chemistry Hoppe-Seyler 1992;373(3):119-22.
1991: David B Hoyt; A N Ozkan; J Frevert; Wolfgang G Junger; W H Loomis
Alteration in Ca2+ homeostasis by a trauma peptide.
The Journal of surgical research 1991;51(6):477-83.
1988: Wolfgang G Junger; S Hallström; H Redl; G Schlag
Characterization of sheep alpha-1-proteinase inhibitor: important differences from the human protein.
The American review of respiratory disease 1988;138(5):1358.
1988: Wolfgang G Junger; S Hallström; Heinz Redl; Günther Schlag
Preliminary data on isolation of an elastase-like proteinase and its inhibitor from ovine neutrophil granulocytes.
Biological chemistry Hoppe-Seyler 1988;369 Suppl():63-8.
1988: Heinz Redl; Günther Schlag; C Vogl; A Schiesser; E Paul; M Thurnher; Wolfgang G Junger; L D Traber; D L Traber
The elastase-inhibitor eglin has no effect in an ovine model of endotoxemia.
Biological chemistry Hoppe-Seyler 1988;369 Suppl():153-6.