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Hans Junginger

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Devices

Drug Delivery Systems

Anatomy

Physiology

Phenomena

Permeability

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Procedures

Oral Administration

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Nanoparticles

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Co-Publications
Name
47
Verhoef, Jan
36
Borchard, Gerrit
23
Bouwstra, Joke
23
Boddé, Harry
13
Thanou, Maya
10
Rafiee-Tehrani, Morteza
9
de Boer, Albertus
9
Dorkoosh, Farid
8
Florea, Bogdan
8
Kotzé, Awie
7
Luessen, HL
6
de Sousa, Adriano
6
Borges, Olga
6
Bivas-Benita, Maytal
6
Romeijn, Stefan

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Publications

TOP 3
Bivas-Benita Maytal; Lin May Young; Bal Suzanne M; van Meijgaarden Krista E; Franken Kees L M C; Friggen Annemieke H; Junginger Hans E; Borchard Gerrit; Klein Michèl R; Ottenhoff Tom H M
Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice.
Sadeghi A M M; Avadi M R; Ejtemaimehr Sh; Abashzadeh Sh; Partoazar A; Dorkoosh F; Faghihi M; Rafiee-Tehrani M; Junginger H E
Development of a Gas Empowered Drug Delivery system for peptide delivery in the small intestine.
Borges Olga; Silva Marta; de Sousa Adriano; Borchard Gerrit; Junginger Hans E; Cordeiro-da-Silva Anabela
Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen.

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All Publications

2009: Bivas-Benita Maytal; Lin May Young; Bal Suzanne M; van Meijgaarden Krista E; Franken Kees L M C; Friggen Annemieke H; Junginger Hans E; Borchard Gerrit; Klein Michèl R; Ottenhoff Tom H M
Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice.
Vaccine 2009;27(30):4010-7.
2009: Sadeghi A M M; Avadi M R; Ejtemaimehr Sh; Abashzadeh Sh; Partoazar A; Dorkoosh F; Faghihi M; Rafiee-Tehrani M; Junginger H E
Development of a Gas Empowered Drug Delivery system for peptide delivery in the small intestine.
Journal of controlled release : official journal of the Controlled Release Society 2009;134(1):11-7.
2008: Borges Olga; Silva Marta; de Sousa Adriano; Borchard Gerrit; Junginger Hans E; Cordeiro-da-Silva Anabela
Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen.
International immunopharmacology 2008;8(13-14):1773-80.
2008: Sadeghi A M M; Dorkoosh F A; Avadi M R; Weinhold M; Bayat A; Delie F; Gurny R; Larijani B; Rafiee-Tehrani M; Junginger H E
Permeation enhancer effect of chitosan and chitosan derivatives: comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(1):270-8.
2008: Borges Olga; Cordeiro-da-Silva Anabela; Tavares Joana; Santarém Nuno; de Sousa Adriano; Borchard Gerrit; Junginger Hans E
Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(2):405-16.
2008: Bayat Akbar; Larijani Bagher; Ahmadian Shahin; Junginger Hans E; Rafiee-Tehrani Morteza
Preparation and characterization of insulin nanoparticles using chitosan and its quaternized derivatives.
Nanomedicine : nanotechnology, biology, and medicine 2008;4(2):115-20.
2008: Bayat Akbar; Dorkoosh Farid A; Dehpour Ahmad Reza; Moezi Leila; Larijani Bagher; Junginger Hans E; Rafiee-Tehrani Morteza
Nanoparticles of quaternized chitosan derivatives as a carrier for colon delivery of insulin: ex vivo and in vivo studies.
International journal of pharmaceutics 2008;356(1-2):259-66.
2008: Sadeghi A M M; Dorkoosh F A; Avadi M R; Saadat P; Rafiee-Tehrani M; Junginger H E
Preparation, characterization and antibacterial activities of chitosan, N-trimethyl chitosan (TMC) and N-diethylmethyl chitosan (DEMC) nanoparticles loaded with insulin using both the ionotropic gelation and polyelectrolyte complexation methods.
International journal of pharmaceutics 2008;355(1-2):299-306.
2007: Borges Olga; Tavares Joana; de Sousa Adriano; Borchard Gerrit; Junginger Hans E; Cordeiro-da-Silva Anabela
Evaluation of the immune response following a short oral vaccination schedule with hepatitis B antigen encapsulated into alginate-coated chitosan nanoparticles.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;32(4-5):278-90.
2007: Boonyo Worawan; Junginger Hans E; Waranuch Neti; Polnok Assadang; Pitaksuteepong Tasana
Chitosan and trimethyl chitosan chloride (TMC) as adjuvants for inducing immune responses to ovalbumin in mice following nasal administration.
Journal of controlled release : official journal of the Controlled Release Society 2007;121(3):168-75.
2007: Borges Olga; Borchard Gerrit; de Sousa Adriano; Junginger Hans E; Cordeiro-da-Silva Anabela
Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers.
International journal of pharmaceutics 2007;337(1-2):254-64.
2007: Amidi Maryam; Romeijn Stefan G; Verhoef J Coos; Junginger Hans E; Bungener Laura; Huckriede Anke; Crommelin Daan J A; Jiskoot Wim
N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model.
Vaccine 2007;25(1):144-53.
2006: Borges Olga; Cordeiro-da-Silva Anabela; Romeijn Stefan G; Amidi Maryam; de Sousa Adriano; Borchard Gerrit; Junginger Hans E
Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination.
Journal of controlled release : official journal of the Controlled Release Society 2006;114(3):348-58.
2006: Amidi Maryam; Romeijn Stefan G; Borchard Gerrit; Junginger Hans E; Hennink Wim E; Jiskoot Wim
Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system.
Journal of controlled release : official journal of the Controlled Release Society 2006;111(1-2):107-16.
2006: Florea Bogdan I; Thanou Maya; Junginger Hans E; Borchard Gerrit
Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation.
Journal of controlled release : official journal of the Controlled Release Society 2006;110(2):353-61.
2005: Bivas-Benita Maytal; Zwier Raphaël; Junginger Hans E; Borchard Gerrit
Non-invasive pulmonary aerosol delivery in mice by the endotracheal route.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2005;61(3):214-8.
2005: Baudner Barbara C; Verhoef J Coos; Giuliani Marzia M; Peppoloni Samuele; Rappuoli Rino; Del Giudice Giuseppe; Junginger Hans E
Protective immune responses to meningococcal C conjugate vaccine after intranasal immunization of mice with the LTK63 mutant plus chitosan or trimethyl chitosan chloride as novel delivery platform.
Journal of drug targeting 2005;13(8-9):489-98.
2005: Bivas-Benita Maytal; Ottenhoff Tom H M; Junginger Hans E; Borchard Gerrit
Pulmonary DNA vaccination: concepts, possibilities and perspectives.
Journal of controlled release : official journal of the Controlled Release Society 2005;107(1):1-29.
2005: Borges Olga; Borchard Gerrit; Verhoef J Coos; de Sousa Adriano; Junginger Hans E
Preparation of coated nanoparticles for a new mucosal vaccine delivery system.
International journal of pharmaceutics 2005;299(1-2):155-66.
2004: Bivas-Benita Maytal; Oudshoorn Marion; Romeijn Stefan; van Meijgaarden Krista; Koerten Henk; van der Meulen Hans; Lambert Gregory; Ottenhoff Tom; Benita Simon; Junginger Hans; Borchard Gerrit
Cationic submicron emulsions for pulmonary DNA immunization.
Journal of controlled release : official journal of the Controlled Release Society 2004;100(1):145-55.
2004: Dorkoosh F A; Stokkel M P M; Blok D; Borchard G; Rafiee-Tehrani M; Verhoef J C; Junginger H E
Feasibility study on the retention of superporous hydrogel composite polymer in the intestinal tract of man using scintigraphy.
Journal of controlled release : official journal of the Controlled Release Society 2004;99(2):199-206.
2004: van der Merwe S M; Verhoef J C; Verheijden J H M; Kotzé A F; Junginger H E
Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(2):225-35.
2004: Bivas-Benita Maytal; Romeijn Stefan; Junginger Hans E; Borchard Gerrit
PLGA-PEI nanoparticles for gene delivery to pulmonary epithelium.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(1):1-6.
2004: Bivas-Benita Maytal; van Meijgaarden Krista E; Franken Kees L M C; Junginger Hans E; Borchard Gerrit; Ottenhoff Tom H M; Geluk Annemieke
Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A*0201-restricted T-cell epitopes of Mycobacterium tuberculosis.
Vaccine 2004;22(13-14):1609-15.
2004: Baudner Barbara C; Morandi Maurizio; Giuliani Marzia M; Verhoef J Coos; Junginger Hans E; Costantino Paolo; Rappuoli Rino; Del Giudice Giuseppe
Modulation of immune response to group C meningococcal conjugate vaccine given intranasally to mice together with the LTK63 mucosal adjuvant and the trimethyl chitosan delivery system.
The Journal of infectious diseases 2004;189(5):828-32.
2004: Dorkoosh Farid A; Broekhuizen Corine A N; Borchard Gerrit; Rafiee-Tehrani Morteza; Verhoef J Coos; Junginger Hans E
Transport of octreotide and evaluation of mechanism of opening the paracellular tight junctions using superporous hydrogel polymers in Caco-2 cell monolayers.
Journal of pharmaceutical sciences 2004;93(3):743-52.
2004: van der Merwe S M; Verhoef J C; Kotzé A F; Junginger H E
N-trimethyl chitosan chloride as absorption enhancer in oral peptide drug delivery. Development and characterization of minitablet and granule formulations.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;57(1):85-91.
2004: Polnok A; Borchard G; Verhoef J C; Sarisuta N; Junginger H E
Influence of methylation process on the degree of quaternization of N-trimethyl chitosan chloride.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;57(1):77-83.
2004: Polnok Assadang; Verhoef J Coos; Borchard Gerrit; Sarisuta Narong; Junginger Hans E
In vitro evaluation of intestinal absorption of desmopressin using drug-delivery systems based on superporous hydrogels.
International journal of pharmaceutics 2004;269(2):303-10.
2003: Baudner Barbara C; Giuliani Marzia M; Verhoef J Coos; Rappuoli Rino; Junginger Hans E; Giudice Giuseppe Del
The concomitant use of the LTK63 mucosal adjuvant and of chitosan-based delivery system enhances the immunogenicity and efficacy of intranasally administered vaccines.
Vaccine 2003;21(25-26):3837-44.
2003: Florea B I; Molenaar T J M; Bot I; Michon I N; Kuiper J; Van Berkel T J C; Junginger H E; Biessen E A L; Borchard G
Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways.
Journal of drug targeting 2003;11(7):383-90.
2003: van der Lubben Inez M; Kersten Gideon; Fretz Marjan M; Beuvery Coen; Coos Verhoef J; Junginger Hans E
Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice.
Vaccine 2003;21(13-14):1400-8.
2003: Florea Bogdan I; Cassara Maria L; Junginger Hans E; Borchard Gerrit
Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3.
Journal of controlled release : official journal of the Controlled Release Society 2003;87(1-3):131-8.
2002: Dorkoosh F A; Verhoef J C; Borchard G; Rafiee-Tehrani M; Verheijden J H M; Junginger H E
Intestinal absorption of human insulin in pigs using delivery systems based on superporous hydrogel polymers.
International journal of pharmaceutics 2002;247(1-2):47-55.
2002: Dorkoosh Farid A; Verhoef J Coos; Verheijden Jos H M; Rafiee-Tehrani Morteza; Borchard Gerrit; Junginger Hans E
Peroral absorption of octreotide in pigs formulated in delivery systems on the basis of superporous hydrogel polymers.
Pharmaceutical research 2002;19(10):1532-6.
2002: van der Lubben I M; van Opdorp F A C; Hengeveld M R; Onderwater J J M; Koerten H K; Verhoef J C; Borchard G; Junginger H E
Transport of chitosan microparticles for mucosal vaccine delivery in a human intestinal M-cell model.
Journal of drug targeting 2002;10(6):449-56.
2002: Honeywell-Nguyen P Loan; Frederik Peter M; Bomans Paul H H; Junginger Hans E; Bouwstra Joke A
Transdermal delivery of pergolide from surfactant-based elastic and rigid vesicles: characterization and in vitro transport studies.
Pharmaceutical research 2002;19(7):991-7.
2002: Dorkoosh Farid A; Setyaningsih Dewi; Borchard Gerrit; Rafiee-Tehrani Morteza; Verhoef J Coos; Junginger Hans E
Effects of superporous hydrogels on paracellular drug permeability and cytotoxicity studies in Caco-2 cell monolayers.
International journal of pharmaceutics 2002;241(1):35-45.
2002: Borchard Gerrit; Cassará María Luz; Roemelé Peter E H; Florea Bogdan I; Junginger Hans E
Transport and local metabolism of budesonide and fluticasone propionate in a human bronchial epithelial cell line (Calu-3).
Journal of pharmaceutical sciences 2002;91(6):1561-7.
2002: Dorkoosh Farid A; Coos Verhoef J; Ambagts Matheus H C; Rafiee-Tehrani Morteza; Borchard Gerrit; Junginger Hans E
Peroral delivery systems based on superporous hydrogel polymers: release characteristics for the peptide drugs buserelin, octreotide and insulin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(5):433-9.
2002: Dorkoosh Farid A; Borchard Gerrit; Rafiee-Tehrani Morteza; Verhoef J Coos; Junginger Hans E
Evaluation of superporous hydrogel (SPH) and SPH composite in porcine intestine ex-vivo: assessment of drug transport, morphology effect, and mechanical fixation to intestinal wall.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2002;53(2):161-6.
2002: Thanou M; Florea B I; Geldof M; Junginger H E; Borchard G
Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines.
Biomaterials 2002;23(1):153-9.
2002: Florea Bogdan I; Meaney Clare; Junginger Hans E; Borchard Gerrit
Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures.
AAPS pharmSci 2002;4(3):E12.
2001: Florea B I; van der Sandt I C; Schrier S M; Kooiman K; Deryckere K; de Boer A G; Junginger H E; Borchard G
Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3).
British journal of pharmacology 2001;134(7):1555-63.
2001: Thanou M; Verhoef J C; Nihot M T; Verheijden J H; Junginger H E
Enhancement of the intestinal absorption of low molecular weight heparin (LMWH) in rats and pigs using Carbopol 934P.
Pharmaceutical research 2001;18(11):1638-41.
2001: van der Lubben I M; Verhoef J C; Borchard G; Junginger H E
Chitosan for mucosal vaccination.
Advanced drug delivery reviews 2001;52(2):139-44.
2001: Thanou M; Verhoef J C; Junginger H E
Oral drug absorption enhancement by chitosan and its derivatives.
Advanced drug delivery reviews 2001;52(2):117-26.
2001: Borchard G; Junginger H E
Modern drug delivery applications of chitosan.
Advanced drug delivery reviews 2001;52(2):103.
2001: van der Lubben I M; Verhoef J C; Borchard G; Junginger H E
Chitosan and its derivatives in mucosal drug and vaccine delivery.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;14(3):201-7.
2001: Thanou M; Verhoef J C; Junginger H E
Chitosan and its derivatives as intestinal absorption enhancers.
Advanced drug delivery reviews 2001;50 Suppl 1():S91-101.
2001: Pechtold L A; Boddé H E; Junginger H E; Koerten H K; Bouwstra J A
X-ray microanalysis of cryopreserved human skin to study the effect of iontophoresis on percutaneous ion transport.
Pharmaceutical research 2001;18(7):1012-7.
2001: Thanou M; Verhoef J C; Verheijden J H; Junginger H E
Intestinal absorption of octreotide using trimethyl chitosan chloride: studies in pigs.
Pharmaceutical research 2001;18(6):823-8.
2001: Dorkoosh F A; Verhoef J C; Borchard G; Rafiee-Tehrani M; Junginger H E
Development and characterization of a novel peroral peptide drug delivery system.
Journal of controlled release : official journal of the Controlled Release Society 2001;71(3):307-18.
2001: van den Bergh B A; Wertz P W; Junginger H E; Bouwstra J A
Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements.
International journal of pharmaceutics 2001;217(1-2):13-24.
2001: van der Lubben I M; Verhoef J C; van Aelst A C; Borchard G; Junginger H E
Chitosan microparticles for oral vaccination: preparation, characterization and preliminary in vivo uptake studies in murine Peyer's patches.
Biomaterials 2001;22(7):687-94.
2001: Thanou M; Nihot M T; Jansen M; Verhoef J C; Junginger H E
Mono-N-carboxymethyl chitosan (MCC), a polyampholytic chitosan derivative, enhances the intestinal absorption of low molecular weight heparin across intestinal epithelia in vitro and in vivo.
Journal of pharmaceutical sciences 2001;90(1):38-46.
2001: Van Der Lubben I M; Konings F A; Borchard G; Verhoef J C; Junginger H E
In vivo uptake of chitosan microparticles by murine Peyer's patches: visualization studies using confocal laser scanning microscopy and immunohistochemistry.
Journal of drug targeting 2001;9(1):39-47.
2000: Thanou M; Verhoef J C; Marbach P; Junginger H E
Intestinal absorption of octreotide: N-trimethyl chitosan chloride (TMC) ameliorates the permeability and absorption properties of the somatostatin analogue in vitro and in vivo.
Journal of pharmaceutical sciences 2000;89(7):951-7.
2000: Thanou M M; Kotzé A F; Scharringhausen T; Luessen H L; de Boer A G; Verhoef J C; Junginger H E
Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal caco-2 cell monolayers.
Journal of controlled release : official journal of the Controlled Release Society 2000;64(1-3):15-25.
2000: Thanou M; Florea B I; Langemeÿer M W; Verhoef J C; Junginger H E
N-trimethylated chitosan chloride (TMC) improves the intestinal permeation of the peptide drug buserelin in vitro (Caco-2 cells) and in vivo (rats).
Pharmaceutical research 2000;17(1):27-31.
2000: Neelissen J A; Arth C; Wolff M; Schrijvers A H; Junginger H E; Boddé H E
Visualization of percutaneous 3H-estradiol and 3H-norethindrone acetate transport across human epidermis as a function of time.
Acta dermato-venereologica. Supplementum 2000;208():36-43.
1999: van den Bergh B A; Bouwstra J A; Junginger H E; Wertz P W
Elasticity of vesicles affects hairless mouse skin structure and permeability.
Journal of controlled release : official journal of the Controlled Release Society 1999;62(3):367-79.
1999: Neelissen J A; Schrijvers A H; Junginger H E; Boddé H E
Reflection contrast microscopy for high resolution detection of (3)H-estradiol in ultrathin sections of human stratum corneum.
Microscopy research and technique 1999;47(4):286-90.
1999: van den Bergh B A; Vroom J; Gerritsen H; Junginger H E; Bouwstra J A
Interactions of elastic and rigid vesicles with human skin in vitro: electron microscopy and two-photon excitation microscopy.
Biochimica et biophysica acta 1999;1461(1):155-73.
1999: Junginger H E; Hoogstraate J A; Verhoef J C
Recent advances in buccal drug delivery and absorption--in vitro and in vivo studies.
Journal of controlled release : official journal of the Controlled Release Society 1999;62(1-2):149-59.
1999: Rentel C O; Bouwstra J A; Naisbett B; Junginger H E
Niosomes as a novel peroral vaccine delivery system.
International journal of pharmaceutics 1999;186(2):161-7.
1999: Thanou M M; Verhoef J C; Romeijn S G; Nagelkerke J F; Merkus F W; Junginger H E
Effects of N-trimethyl chitosan chloride, a novel absorption enhancer, on caco-2 intestinal epithelia and the ciliary beat frequency of chicken embryo trachea.
International journal of pharmaceutics 1999;185(1):73-82.
1999: Kotzé A F; Thanou M M; Luessen H L; de Boer B G; Verhoef J C; Junginger H E
Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2).
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1999;47(3):269-74.
1999: Tanojo H; Boelsma E; Junginger H E; Ponec M; Boddé H E
In vivo human skin permeability enhancement by oleic acid: a laser Doppler velocimetry study.
Journal of controlled release : official journal of the Controlled Release Society 1999;58(1):97-104.
1999: Kotzé A F; Thanou M M; Luebetaen H L; de Boer A G; Verhoef J C; Junginger H E
Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: in vitro evaluation in intestinal epithelial cells (Caco-2).
Journal of pharmaceutical sciences 1999;88(2):253-7.
1999: Kotzé A F; Luessen H L; de Boer A G; Verhoef J C; Junginger H E
Chitosan for enhanced intestinal permeability: prospects for derivatives soluble in neutral and basic environments.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1999;7(2):145-51.
1998: van Kuijk-Meuwissen M E; Mougin L; Junginger H E; Bouwstra J A
Application of vesicles to rat skin in vivo: a confocal laser scanning microscopy study.
Journal of controlled release : official journal of the Controlled Release Society 1998;56(1-3):189-96.
1998: van Kuijk-Meuwissen M E; Junginger H E; Bouwstra J A
Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study.
Biochimica et biophysica acta 1998;1371(1):31-9.
1998: Tanojo H; Boelsma E; Junginger H E; Ponec M; Boddé H E
In vivo human skin barrier modulation by topical application of fatty acids.
Skin pharmacology and applied skin physiology 1998;11(2):87-97.
1998: Meuwissen M E; Janssen J; Cullander C; Junginger H E; Bouwstra J A
A cross-section device to improve visualization of fluorescent probe penetration into the skin by confocal laser scanning microscopy.
Pharmaceutical research 1998;15(2):352-6.
1998: Kotzé A F; Luessen H L; de Leeuw B J; de Boer A G; Verhoef J C; Junginger H E
Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2).
Journal of controlled release : official journal of the Controlled Release Society 1998;51(1):35-46.
1998: Neelissen J A; Arth C; Schrijvers A H; Junginger H E; Boddé H E
Validation of freeze-drying to visualize percutaneous 3H-estradiol transport: the influence of skin hydration on the efficacy of the method.
Skin pharmacology and applied skin physiology 1998;11(1):11-22.
1997: Kotzé A F; Luessen H L; de Leeuw B J; de Boer B G; Verhoef J C; Junginger H E
N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces: in vitro evaluation in intestinal epithelial cells (Caco-2).
Pharmaceutical research 1997;14(9):1197-202.
1997: Van den Bergh B A; Swartzendruber D C; Bos-Van der Geest A; Hoogstraate J J; Schrijvers A H; Boddé H E; Junginger H E; Bouwstra J A
Development of an optimal protocol for the ultrastructural examination of skin by transmission electron microscopy.
Journal of microscopy 1997;187(Pt 2):125-33.
1997: Craane-Van Hinsberg I W; Verhoef J C; Spies F; Bouwstra J A; Gooris G S; Junginger H E; Boddé H E
Electroperturbation of the human skin barrier in vitro: II. Effects on stratum corneum lipid ordering and ultrastructure.
Microscopy research and technique 1997;37(3):200-13.
1997: Tanojo H; Bouwstra J A; Junginger H E; Boddé H E
In vitro human skin barrier modulation by fatty acids: skin permeation and thermal analysis studies.
Pharmaceutical research 1997;14(1):42-9.
1996: Luessen H L; de Leeuw B J; Langemeÿer M W; de Boer A B; Verhoef J C; Junginger H E
Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo.
Pharmaceutical research 1996;13(11):1668-72.
1996: Hoogstraate A J; Coos Verhoef J; Pijpers A; van Leengoed L A; Verheijden J H; Junginger H E; Boddé H E
In vivo buccal delivery of the peptide drug buserelin with glycodeoxycholate as an absorption enhancer in pigs.
Pharmaceutical research 1996;13(8):1233-7.
1996: Hoogstraate A J; Verhoef J C; Tuk B; Pijpers A; van Leengoed L A; Verheijden J H; Junginger H E; Boddé H E
In-vivo buccal delivery of fluorescein isothiocyanate-dextran 4400 with glycodeoxycholate as an absorption enhancer in pigs.
Journal of pharmaceutical sciences 1996;85(5):457-60.
1996: Van Hal D A; Jeremiasse E; Junginger H E; Spies F; Bouwstra J A
Structure of fully hydrated human stratum corneum: a freeze-fracture electron microscopy study.
The Journal of investigative dermatology 1996;106(1):89-95.
1995: Craane-van Hinsberg W H; Verhoef J C; Bax L J; Junginger H E; Boddé H E
Role of appendages in skin resistance and iontophoretic peptide flux: human versus snake skin.
Pharmaceutical research 1995;12(10):1506-12.
1995: Luessen H L; Verhoef J C; Borchard G; Lehr C M; de Boer A G; Junginger H E
Mucoadhesive polymers in peroral peptide drug delivery. II. Carbomer and polycarbophil are potent inhibitors of the intestinal proteolytic enzyme trypsin.
Pharmaceutical research 1995;12(9):1293-8.
1995: Hofland H E; Bouwstra J A; Boddé H E; Spies F; Junginger H E
Interactions between liposomes and human stratum corneum in vitro: freeze fracture electron microscopical visualization and small angle X-ray scattering studies.
The British journal of dermatology 1995;132(6):853-66.
1994: Tanojo H; Bouwstra J A; Junginger H E; Boddé H E
Subzero thermal analysis of human stratum corneum.
Pharmaceutical research 1994;11(11):1610-6.
1994: Craane-van Hinsberg W H; Bax L; Flinterman N H; Verhoef J; Junginger H E; Boddé H E
Iontophoresis of a model peptide across human skin in vitro: effects of iontophoresis protocol, pH, and ionic strength on peptide flux and skin impedance.
Pharmaceutical research 1994;11(9):1296-300.
1994: Hofland H E; van der Geest R; Bodde H E; Junginger H E; Bouwstra J A
Estradiol permeation from nonionic surfactant vesicles through human stratum corneum in vitro.
Pharmaceutical research 1994;11(5):659-64.
1994: Hoogstraate A J; Cullander C; Nagelkerke J F; Senel S; Verhoef J C; Junginger H E; Boddé H E
Diffusion rates and transport pathways of fluorescein isothiocyanate (FITC)-labeled model compounds through buccal epithelium.
Pharmaceutical research 1994;11(1):83-9.
1993: Peschier L J; Bouwstra J A; de Bleyser J; Junginger H E; Leyte J C
Water mobility and structure in poly[2-hydroxyethylmethacrylate] hydrogels by means of the pulsed field gradient NMR technique.
Biomaterials 1993;14(12):945-52.
1993: Senel S; Hoogstraate A J; Spies F; Verhoef J C; Junginger H E; Boddé H E
Visualization of enhancing effects of bile salts on buccal penetration.
European journal of morphology 1993;31(1-2):35-41.
1992: Lehr C M; Bouwstra J A; Kok W; De Boer A G; Tukker J J; Verhoef J C; Breimer D D; Junginger H E
Effects of the mucoadhesive polymer polycarbophil on the intestinal absorption of a peptide drug in the rat.
The Journal of pharmacy and pharmacology 1992;44(5):402-7.
1992: Lehr C M; Bouwstra J A; Kok W; Noach A B; de Boer A G; Junginger H E
Bioadhesion by means of specific binding of tomato lectin.
Pharmaceutical research 1992;9(4):547-53.
1992: Hofland H E; Bouwstra J A; Verhoef J C; Buckton G; Chowdry B Z; Ponec M; Junginger H E
Safety aspects of non-ionic surfactant vesicles: a toxicity study related to the physicochemical characteristics of non-ionic surfactants.
The Journal of pharmacy and pharmacology 1992;44(4):287-94.
1992: Lehr C M; Bouwstra J A; Boddé H E; Junginger H E
A surface energy analysis of mucoadhesion: contact angle measurements on polycarbophil and pig intestinal mucosa in physiologically relevant fluids.
Pharmaceutical research 1992;9(1):70-5.
1991: de Vries M E; Boddé H E; Verhoef J C; Junginger H E
Developments in buccal drug delivery.
Critical reviews in therapeutic drug carrier systems 1991;8(3):271-303.
1990: Verhoef J C; Boddé H E; de Boer A G; Bouwstra J A; Junginger H E; Merkus F W; Breimer D D
Transport of peptide and protein drugs across biological membranes.
European journal of drug metabolism and pharmacokinetics 1990;15(2):83-93.
1990: Roorda W E; de Bleyser J; Junginger H E; Leyte J C
Nuclear magnetic relaxation of water in hydrogels.
Biomaterials 1990;11(1):17-23.
1989: Boddé H E; Van Aalten E A; Junginger H E
Hydrogel patches for transdermal drug delivery; in-vivo water exchange and skin compatibility.
The Journal of pharmacy and pharmacology 1989;41(3):152-5.
1988: Roorda W E; Bouwstra J A; de Vries M A; Junginger H E
Thermal behavior of poly hydroxy ethyl methacrylate (pHEMA) hydrogels.
Pharmaceutical research 1988;5(11):722-5.
1988: de Vries M E; Boddé H E; Busscher H J; Junginger H E
Hydrogels for buccal drug delivery: properties relevant for muco-adhesion.
Journal of biomedical materials research 1988;22(11):1023-32.
1988: Roorda W E; Bouwstra J A; de Vries M A; Junginger H E
Thermal analysis of water in p(HEMA) hydrogels.
Biomaterials 1988;9(6):494-9.
1987: Roorda W E; Verbeek J; Junginger H E
Simple gas chromatographic determination of the purity of hydroxyethyl methacrylate.
Journal of chromatography 1987;403():355-7.
1986: Baggerman C; Bonekamp B C; Kannegieter E M; Loos J A; Junginger H E
Electrokinetic properties of endotoxins and their significance for the limulus amoebocyte lysate test.
The Journal of pharmacy and pharmacology 1986;38(7):510-4.
1985: Baggerman C; Pathmamanoharan C; Spies F; Joosten J G; Junginger H E
Physicochemical properties of endotoxins in large volume parenterals.
The Journal of pharmacy and pharmacology 1985;37(8):521-7.
1985: Hurkmans J F; Boddé H E; Van Driel L M; Van Doorne H; Junginger H E
Skin irritation caused by transdermal drug delivery systems during long-term (5 days) application.
The British journal of dermatology 1985;112(4):461-7.

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