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Ingo Just
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Chemicals & Drugs
Living Beings
Phenomena
Genes & Molecular Sequences
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64
Aktories, Klaus
19
Genth, Harald
17
Gerhard, Ralf
16
Hofmann, Franz
8
Selzer, J
6
von Eichel-Streiber, Christoph
6
Sehr, Peter
5
Wilde, Christian
5
Tatge, Helma
5
Huelsenbeck, Johannes
4
Fritz, Gerhard
4
Prepens, U
3
Chhatwal, Gursharan
3
Barth, Holger
3
Wegner, Albrecht
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All Publications
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2009: Schulz Florian; Just Ingo; Genth Harald
Prevention of Clostridium sordellii lethal toxin-induced apoptotic cell death by tauroursodeoxycholic acid.
Biochemistry 2009;48(38):9002-10.
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2009: Nerlich Andreas; Rohde Manfred; Talay Susanne R; Genth Harald; Just Ingo; Chhatwal Gursharan S
Invasion of endothelial cells by tissue-invasive M3 type group A streptococci requires Src kinase and activation of Rac1 by a phosphatidylinositol 3-kinase-independent mechanism.
The Journal of biological chemistry 2009;284(30):20319-28.
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2009: Muetzelburg M V; Hofmann F; Just I; Pich A
Identification of biomarkers indicating cellular changes after treatment of neuronal cells with the C3 exoenzyme from Clostridium botulinum using the iTRAQ protocol and LC-MS/MS analysis.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(13):1344-51.
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2008: Halabi-Cabezon Ismael; Huelsenbeck Johannes; May Martin; Ladwein Markus; Rottner Klemens; Just Ingo; Genth Harald
Prevention of the cytopathic effect induced by Clostridium difficile Toxin B by active Rac1.
FEBS letters 2008;582(27):3751-6.
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2008: Gerhard Ralf; Nottrott Stefanie; Schoentaube Janett; Tatge Helma; Olling Alexandra; Just Ingo
Glucosylation of Rho GTPases by Clostridium difficile toxin A triggers apoptosis in intestinal epithelial cells.
Journal of medical microbiology 2008;57(Pt 6):765-70.
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2008: Genth Harald; Dreger Stefanie C; Huelsenbeck Johannes; Just Ingo
Clostridium difficile toxins: more than mere inhibitors of Rho proteins.
The international journal of biochemistry & cell biology 2008;40(4):592-7.
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2007: Meyer Gesa K A; Neetz Anne; Brandes Gudrun; Tsikas Dimitrios; Butterfield Joseph H; Just Ingo; Gerhard Ralf
Clostridium difficile toxins A and B directly stimulate human mast cells.
Infection and immunity 2007;75(8):3868-76.
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2007: Nottrott Stefanie; Schoentaube Janett; Genth Harald; Just Ingo; Gerhard Ralf
Clostridium difficile toxin A-induced apoptosis is p53-independent but depends on glucosylation of Rho GTPases.
Apoptosis : an international journal on programmed cell death 2007;12(8):1443-53.
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2007: Conrad Sabine; Genth Harald; Hofmann Fred; Just Ingo; Skutella Thomas
Neogenin-RGMa signaling at the growth cone is bone morphogenetic protein-independent and involves RhoA, ROCK, and PKC.
The Journal of biological chemistry 2007;282(22):16423-33.
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2007: Huelsenbeck Johannes; Dreger Stefanie C; Gerhard Ralf; Fritz Gerhard; Just Ingo; Genth Harald
Upregulation of the immediate early gene product RhoB by exoenzyme C3 from Clostridium limosum and toxin B from Clostridium difficile.
Biochemistry 2007;46(16):4923-31.
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2007: Huelsenbeck Johannes; Dreger Stefanie; Gerhard Ralf; Barth Holger; Just Ingo; Genth Harald
Difference in the cytotoxic effects of toxin B from Clostridium difficile strain VPI 10463 and toxin B from variant Clostridium difficile strain 1470.
Infection and immunity 2007;75(2):801-9.
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2006: Teichert Matthias; Tatge Helma; Schoentaube Janett; Just Ingo; Gerhard Ralf
Application of mutated Clostridium difficile toxin A for determination of glucosyltransferase-dependent effects.
Infection and immunity 2006;74(10):6006-10.
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2006: Genth Harald; Huelsenbeck Johannes; Hartmann Birgit; Hofmann Fred; Just Ingo; Gerhard Ralf
Cellular stability of Rho-GTPases glucosylated by Clostridium difficile toxin B.
FEBS letters 2006;580(14):3565-9.
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2006: Molinari Gabriella; Rohde Manfred; Wilde Christian; Just Ingo; Aktories Klaus; Chhatwal Gursharan S
Localization of the C3-Like ADP-ribosyltransferase from Staphylococcus aureus during bacterial invasion of mammalian cells.
Infection and immunity 2006;74(6):3673-7.
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2006: Giesemann Torsten; Jank Thomas; Gerhard Ralf; Maier Elke; Just Ingo; Benz Roland; Aktories Klaus
Cholesterol-dependent pore formation of Clostridium difficile toxin A.
The Journal of biological chemistry 2006;281(16):10808-15.
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2005: Gerhard Ralf; Burger Silke; Tatge Helma; Genth Harald; Just Ingo; Hofmann Fred
Comparison of wild type with recombinant Clostridium difficile toxin A.
Microbial pathogenesis 2005;38(2-3):77-83.
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2005: Gerhard Ralf; Tatge Helma; Genth Harald; Thum Thomas; Borlak Jürgen; Fritz Gerhard; Just Ingo
Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB.
The Journal of biological chemistry 2005;280(2):1499-505.
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2005: Aktories K; Just I
Clostridial Rho-inhibiting protein toxins.
Current topics in microbiology and immunology 2005;291():113-45.
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2004: Just I; Gerhard R
Large clostridial cytotoxins.
Reviews of physiology, biochemistry and pharmacology 2004;152():23-47.
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2003: Burger Silke; Tatge Helma; Hofmann Fred; Genth Harald; Just Ingo; Gerhard Ralf
Expression of recombinant Clostridium difficile toxin A using the Bacillus megaterium system.
Biochemical and biophysical research communications 2003;307(3):584-8.
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2003: Genth Harald; Gerhard Ralf; Maeda Akio; Amano Mutsuki; Kaibuchi Kozo; Aktories Klaus; Just Ingo
Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex.
The Journal of biological chemistry 2003;278(31):28523-7.
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2003: Gerhard Ralf; John Harald; Aktories Klaus; Just Ingo
Thiol-modifying phenylarsine oxide inhibits guanine nucleotide binding of Rho but not of Rac GTPases.
Molecular pharmacology 2003;63(6):1349-55.
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2003: Genth Harald; Schmidt Martina; Gerhard Ralf; Aktories Klaus; Just Ingo
Activation of phospholipase D1 by ADP-ribosylated RhoA.
Biochemical and biophysical research communications 2003;302(1):127-32.
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2003: Frisch Cornelia; Gerhard Ralf; Aktories Klaus; Hofmann Fred; Just Ingo
The complete receptor-binding domain of Clostridium difficile toxin A is required for endocytosis.
Biochemical and biophysical research communications 2003;300(3):706-11.
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2002: Wilde Christian; Barth Holger; Sehr Peter; Han Li; Schmidt Martina; Just Ingo; Aktories Klaus
Interaction of the Rho-ADP-ribosylating C3 exoenzyme with RalA.
The Journal of biological chemistry 2002;277(17):14771-6.
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2002: Schirmer Jörg; Just Ingo; Aktories Klaus
The ADP-ribosylating mosquitocidal toxin from Bacillus sphaericus: proteolytic activation, enzyme activity, and cytotoxic effects.
The Journal of biological chemistry 2002;277(14):11941-8.
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2002: Wilde Christian; Just Ingo; Aktories Klaus
Structure-function analysis of the Rho-ADP-ribosylating exoenzyme C3stau2 from Staphylococcus aureus.
Biochemistry 2002;41(5):1539-44.
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2001: Just I; Hofmann F; Genth H; Gerhard R
Bacterial protein toxins inhibiting low-molecular-mass GTP-binding proteins.
International journal of medical microbiology : IJMM 2001;291(4):243-50.
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2001: Wilde C; Chhatwal G S; Schmalzing G; Aktories K; Just I
A novel C3-like ADP-ribosyltransferase from Staphylococcus aureus modifying RhoE and Rnd3.
The Journal of biological chemistry 2001;276(12):9537-42.
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2000: Wilde C; Genth H; Aktories K; Just I
Recognition of RhoA by Clostridium botulinum C3 exoenzyme.
The Journal of biological chemistry 2000;275(22):16478-83.
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2000: Genth H; Selzer J; Busch C; Dumbach J; Hofmann F; Aktories K; Just I
New method to generate enzymatically deficient Clostridium difficile toxin B as an antigen for immunization.
Infection and immunity 2000;68(3):1094-101.
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2000: Just I; Boquet P
Large clostridial cytotoxins as tools in cell biology.
Current topics in microbiology and immunology 2000;250():97-107.
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2000: Just I; Hofmann F; Aktories K
Molecular mode of action of the large clostridial cytotoxins.
Current topics in microbiology and immunology 2000;250():55-83.
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1999: Genth H; Aktories K; Just I
Monoglucosylation of RhoA at threonine 37 blocks cytosol-membrane cycling.
The Journal of biological chemistry 1999;274(41):29050-6.
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1998: Sehr P; Joseph G; Genth H; Just I; Pick E; Aktories K
Glucosylation and ADP ribosylation of rho proteins: effects on nucleotide binding, GTPase activity, and effector coupling.
Biochemistry 1998;37(15):5296-304.
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1998: Barth H; Hofmann F; Olenik C; Just I; Aktories K
The N-terminal part of the enzyme component (C2I) of the binary Clostridium botulinum C2 toxin interacts with the binding component C2II and functions as a carrier system for a Rho ADP-ribosylating C3-like fusion toxin.
Infection and immunity 1998;66(4):1364-9.
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1997: Olenik C; Barth H; Just I; Aktories K; Meyer D K
Gene expression of the small GTP-binding proteins RhoA, RhoB, Rac1, and Cdc42 in adult rat brain.
Brain research. Molecular brain research 1997;52(2):263-9.
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1997: Hofmann F; Busch C; Prepens U; Just I; Aktories K
Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin.
The Journal of biological chemistry 1997;272(17):11074-8.
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1997: Prepens U; Just I; Hofmann F; Aktories K
ADP-ribosylating and glucosylating toxins as tools to study secretion in RBL cells.
Advances in experimental medicine and biology 1997;419():349-53.
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1996: Sehr P; Just I; Aktories K
ADP-ribosylation of actin by Clostridium perfringens iota toxin and turkey erythrocyte ADP-ribosyltransferase A: effects on profilin-regulated nucleotide exchange and ATPase activity.
Naunyn-Schmiedeberg's archives of pharmacology 1996;354(6):693-7.
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1996: Genth H; Hofmann F; Selzer J; Rex G; Aktories K; Just I
Difference in protein substrate specificity between hemorrhagic toxin and lethal toxin from Clostridium sordellii.
Biochemical and biophysical research communications 1996;229(2):370-4.
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1996: Hofmann F; Rex G; Aktories K; Just I
The ras-related protein Ral is monoglucosylated by Clostridium sordellii lethal toxin.
Biochemical and biophysical research communications 1996;227(1):77-81.
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1996: Selzer J; Hofmann F; Rex G; Wilm M; Mann M; Just I; Aktories K
Clostridium novyi alpha-toxin-catalyzed incorporation of GlcNAc into Rho subfamily proteins.
The Journal of biological chemistry 1996;271(41):25173-7.
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1996: Geipel U; Just I; Aktories K
ADP-ribosylation of an approximately 70-kilodalton protein of Klebsiella pneumoniae.
Infection and immunity 1996;64(5):1720-3.
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1996: Just I; Selzer J; Hofmann F; Green G A; Aktories K
Inactivation of Ras by Clostridium sordellii lethal toxin-catalyzed glucosylation.
The Journal of biological chemistry 1996;271(17):10149-53.
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1996: Prepens U; Just I; von Eichel-Streiber C; Aktories K
Inhibition of Fc epsilon-RI-mediated activation of rat basophilic leukemia cells by Clostridium difficile toxin B (monoglucosyltransferase)
The Journal of biological chemistry 1996;271(13):7324-9.
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1996: Kiefer G; Lerner M; Sehr P; Just I; Aktories K
Cytotoxic effects by microinjection of ADP-ribosylated skeletal muscle G-actin in PtK2 cells in the absence of Clostridium perfringens iota toxin.
Medical microbiology and immunology 1996;184(4):175-80.
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1996: Böhmer J; Jung M; Sehr P; Fritz G; Popoff M; Just I; Aktories K
Active site mutation of the C3-like ADP-ribosyltransferase from Clostridium limosum--analysis of glutamic acid 174.
Biochemistry 1996;35(1):282-9.
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1995: Just I; Selzer J; Wilm M; von Eichel-Streiber C; Mann M; Aktories K
Glucosylation of Rho proteins by Clostridium difficile toxin B.
Nature 1995;375(6531):500-3.
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1995: Just I; Wilm M; Selzer J; Rex G; von Eichel-Streiber C; Mann M; Aktories K
The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins.
The Journal of biological chemistry 1995;270(23):13932-6.
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1995: Just I; Selzer J; von Eichel-Streiber C; Aktories K
The low molecular mass GTP-binding protein Rho is affected by toxin A from Clostridium difficile.
The Journal of clinical investigation 1995;95(3):1026-31.
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1995: Just I; Selzer J; Jung M; van Damme J; Vandekerckhove J; Aktories K
Rho-ADP-ribosylating exoenzyme from Bacillus cereus. Purification, characterization, and identification of the NAD-binding site.
Biochemistry 1995;34(1):334-40.
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1995: Just I; Sehr P; Jung M; van Damme J; Puype M; Vandekerckhove J; Moss J; Aktories K
ADP-ribosyltransferase type A from turkey erythrocytes modifies actin at Arg-95 and Arg-372.
Biochemistry 1995;34(1):326-33.
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1995: Aktories K; Jung M; Böhmer J; Fritz G; Vandekerckhove J; Just I
Studies on the active-site structure of C3-like exoenzymes: involvement of glutamic acid in catalysis of ADP-ribosylation.
Biochimie 1995;77(5):326-32.
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1995: Aktories K; Just I
In vitro ADP-ribosylation of Rho by bacterial ADP-ribosyltransferases.
Methods in enzymology 1995;256():184-95.
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1994: Fritz G; Just I; Wollenberg P; Aktories K
Differentiation-induced increase in Clostridium botulinum C3 exoenzyme-catalyzed ADP-ribosylation of the small GTP-binding protein Rho.
European journal of biochemistry / FEBS 1994;223(3):909-16.
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1994: Just I; Richter H P; Prepens U; von Eichel-Streiber C; Aktories K
Probing the action of Clostridium difficile toxin B in Xenopus laevis oocytes.
Journal of cell science 1994;107 ( Pt 6)():1653-9.
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1994: Just I; Wollenberg P; Moss J; Aktories K
Cysteine-specific ADP-ribosylation of actin.
European journal of biochemistry / FEBS 1994;221(3):1047-54.
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1994: Just I; Fritz G; Aktories K; Giry M; Popoff M R; Boquet P; Hegenbarth S; von Eichel-Streiber C
Clostridium difficile toxin B acts on the GTP-binding protein Rho.
The Journal of biological chemistry 1994;269(14):10706-12.
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1994: Schroeder P; Just I; Aktories K
Adenine nucleotides regulate ADP-ribosylation of membrane-bound actin and actin-binding to membranes.
European journal of cell biology 1994;63(1):3-9.
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1994: Wegner A; Aktories K; Ditsch A; Just I; Schoepper B; Selve N; Wille M
Actin-gelsolin interaction.
Advances in experimental medicine and biology 1994;358():97-104.
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1993: Jung M; Just I; van Damme J; Vandekerckhove J; Aktories K
NAD-binding site of the C3-like ADP-ribosyltransferase from Clostridium limosum.
The Journal of biological chemistry 1993;268(31):23215-8.
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1993: Hinsch K D; Habermann B; Just I; Hinsch E; Pfisterer S; Schill W B; Aktories K
ADP-ribosylation of Rho proteins inhibits sperm motility.
FEBS letters 1993;334(1):32-6.
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1993: Just I; Wille M; Chaponnier C; Aktories K
Gelsolin-actin complex is target for ADP-ribosylation by Clostridium botulinum C2 toxin in intact human neutrophils.
European journal of pharmacology 1993;246(3):293-7.
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1993: Just I; Hennessey E S; Drummond D R; Aktories K; Sparrow J C
ADP-ribosylation of Drosophila indirect-flight-muscle actin and arthrin by Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin.
The Biochemical journal 1993;291 ( Pt 2)():409-12.
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1993: Just I; Mohr C; Habermann B; Koch G; Aktories K
Enhancement of Clostridium botulinum C3-catalysed ADP-ribosylation of recombinant rhoA by sodium dodecyl sulfate.
Biochemical pharmacology 1993;45(7):1409-16.
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1992: Koch G; Mohr C; Just I; Aktories K
Posttranslational isoprenylation of rho protein is a prerequisite for its interaction with mastoparan and other amphiphilic agents.
Biochemical and biophysical research communications 1992;186(1):448-54.
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1992: Just I; Mohr C; Schallehn G; Menard L; Didsbury J R; Vandekerckhove J; van Damme J; Aktories K
Purification and characterization of an ADP-ribosyltransferase produced by Clostridium limosum.
The Journal of biological chemistry 1992;267(15):10274-80.
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1992: Koch G; Habermann B; Mohr C; Just I; Aktories K
ADP-ribosylation of rho proteins is inhibited by melittin, mast cell degranulating peptide and compound 48/80.
European journal of pharmacology 1992;226(1):87-91.
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1992: Just I; Schallehn G; Aktories K
ADP-ribosylation of small GTP-binding proteins by Bacillus cereus.
Biochemical and biophysical research communications 1992;183(3):931-6.
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1992: Mohr C; Koch G; Just I; Aktories K
ADP-ribosylation by Clostridium botulinum C3 exoenzyme increases steady-state GTPase activities of recombinant rhoA and rhoB proteins.
FEBS letters 1992;297(1-2):95-9.
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1992: Wille M; Just I; Wegner A; Aktories K
ADP-ribosylation of gelsolin-actin complexes by clostridial toxins.
The Journal of biological chemistry 1992;267(1):50-5.
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1992: Aktories K; Wille M; Just I
Clostridial actin-ADP-ribosylating toxins.
Current topics in microbiology and immunology 1992;175():97-113.
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1991: Koch G; Haberman B; Mohr C; Just I; Aktories K
Interaction of mastoparan with the low molecular mass GTP-binding proteins rho/rac.
FEBS letters 1991;291(2):336-40.
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1991: Grimminger F; Sibelius U; Aktories K; Just I; Seeger W
Suppression of cytoskeletal rearrangement in activated human neutrophils by botulinum C2 toxin. Impact on cellular signal transduction.
The Journal of biological chemistry 1991;266(29):19276-82.
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1991: Habermann B; Mohr C; Just I; Aktories K
ADP-ribosylation and de-ADP-ribosylation of the rho protein by Clostridium botulinum exoenzyme C3. Regulation by EDTA, guanine nucleotides and pH.
Biochimica et biophysica acta 1991;1077(3):253-8.
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1990: Just I; Geipel U; Wegner A; Aktories K
De-ADP-ribosylation actin by Clostridium perfringens iota-toxin and Clostridium botulinum C2 toxin.
European journal of biochemistry / FEBS 1990;192(3):723-7.
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1990: Geipel U; Just I; Aktories K
Inhibition of cytochalasin D-stimulated G-actin ATPase by ADP-ribosylation with Clostridium perfringens iota toxin.
The Biochemical journal 1990;266(2):335-9.
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1990: Aktories K; Geipel U; Wille M; Just I
Characterization of the ADP-ribosylation of actin by Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin.
Journal de physiologie 1990;84(4):262-6.
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1989: Weigt C; Just I; Wegner A; Aktories K
Nonmuscle actin ADP-ribosylated by botulinum C2 toxin caps actin filaments.
FEBS letters 1989;246(1-2):181-4.
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1989: Geipel U; Just I; Schering B; Haas D; Aktories K
ADP-ribosylation of actin causes increase in the rate of ATP exchange and inhibition of ATP hydrolysis.
European journal of biochemistry / FEBS 1989;179(1):229-32.
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1989: Braun U; Habermann B; Just I; Aktories K; Vandekerckhove J
Purification of the 22 kDa protein substrate of botulinum ADP-ribosyltransferase C3 from porcine brain cytosol and its characterization as a GTP-binding protein highly homologous to the rho gene product.
FEBS letters 1989;243(1):70-6.
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1988: Aktories K; Just I; Rosenthal W
Different types of ADP-ribose protein bonds formed by botulinum C2 toxin, botulinum ADP-ribosyltransferase C3 and pertussis toxin.
Biochemical and biophysical research communications 1988;156(1):361-7.
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