Fritz Bach

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Ollinger Robert; Thomas Michael; Kogler Pamela; Hermann Martin; Weiss Helmut; Mark Walter; Bilban Martin; Troppmair Jakob; Bach Fritz H; Margreiter Raimund
Blockade of p38 MAPK inhibits chronic allograft vasculopathy.
Ollinger Robert; Kogler Pamela; Troppmair Jakob; Hermann Martin; Wurm Martin; Drasche Astrid; Königsrainer Ingmar; Amberger Albert; Weiss Helmut; Ofner Dietmar; Bach Fritz H; Margreiter Raimund
Bilirubin inhibits tumor cell growth via activation of ERK.
Ollinger Robert; Wang Hongjun; Yamashita Kenichiro; Wegiel Barbara; Thomas Michael; Margreiter Raimund; Bach Fritz H
Therapeutic applications of bilirubin and biliverdin in transplantation.

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2008: Ollinger Robert; Thomas Michael; Kogler Pamela; Hermann Martin; Weiss Helmut; Mark Walter; Bilban Martin; Troppmair Jakob; Bach Fritz H; Margreiter Raimund
Blockade of p38 MAPK inhibits chronic allograft vasculopathy.
Transplantation 2008;85(2):293-7.
2007: Ollinger Robert; Kogler Pamela; Troppmair Jakob; Hermann Martin; Wurm Martin; Drasche Astrid; Königsrainer Ingmar; Amberger Albert; Weiss Helmut; Ofner Dietmar; Bach Fritz H; Margreiter Raimund
Bilirubin inhibits tumor cell growth via activation of ERK.
Cell cycle (Georgetown, Tex.) 2007;6(24):3078-85.
2007: Ollinger Robert; Wang Hongjun; Yamashita Kenichiro; Wegiel Barbara; Thomas Michael; Margreiter Raimund; Bach Fritz H
Therapeutic applications of bilirubin and biliverdin in transplantation.
Antioxidants & redox signaling 2007;9(12):2175-85.
2007: Lee Soo Sun; Gao Wenda; Mazzola Silvia; Thomas Michael N; Csizmadia Eva; Otterbein Leo E; Bach Fritz H; Wang Hongjun
Heme oxygenase-1, carbon monoxide, and bilirubin induce tolerance in recipients toward islet allografts by modulating T regulatory cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(13):3450-7.
2007: Goldberg Alyssa; Parolini Margherita; Chin Beek Y; Czismadia Eva; Otterbein Leo E; Bach Fritz H; Wang Hongjun
Toll-like receptor 4 suppression leads to islet allograft survival.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(11):2840-8.
2007: Haschemi Arvand; Wagner Oswald; Marculescu Rodrig; Wegiel Barbara; Robson Simon C; Gagliani Nicola; Gallo David; Chen Jiang-Fan; Bach Fritz H; Otterbein Leo E
Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5921-9.
2007: Chin Beek Y; Jiang Ge; Wegiel Barbara; Wang Hong J; Macdonald Theresa; Zhang Xu Chen; Gallo David; Cszimadia Eva; Bach Fritz H; Lee Patty J; Otterbein Leo E
Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5109-14.
2007: Ollinger Robert; Yamashita Kenichiro; Bilban Martin; Erat Anna; Kogler Pamela; Thomas Michael; Csizmadia Eva; Usheva Anny; Margreiter Raimund; Bach Fritz H
Bilirubin and biliverdin treatment of atherosclerotic diseases.
Cell cycle (Georgetown, Tex.) 2007;6(1):39-43.
2006: Bach Fritz H
Carbon monoxide: from the origin of life to molecular medicine.
Trends in molecular medicine 2006;12(8):348-50.
2006: Bach Fritz H
Heme oxygenase-1 and transplantation tolerance.
Human immunology 2006;67(6):430-2.
2006: Bilban Martin; Bach Fritz H; Otterbein Sherrie L; Ifedigbo Emeka; d'Avila Joana de Costa; Esterbauer Harald; Chin Beek Yoke; Usheva Anny; Robson Simon C; Wagner Oswald; Otterbein Leo E
Carbon monoxide orchestrates a protective response through PPARgamma.
Immunity 2006;24(5):601-10.
2006: Yamashita Kenichiro; Ollinger Robert; McDaid James; Sakahama Hideyasu; Wang Hongjun; Tyagi Shivraj; Csizmadia Eva; Smith Neal R; Soares Miguel P; Bach Fritz H
Heme oxygenase-1 is essential for and promotes tolerance to transplanted organs.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(6):776-8.
2006: Wang Hongjun; Lee Soo Sun; Dell'Agnello Carlotta; Tchipashvili Vaja; d'Avila Joana Costa Pinto; Czismadia Eva; Chin Beek Yoke; Bach Fritz H
Bilirubin can induce tolerance to islet allografts.
Endocrinology 2006;147(2):762-8.
2005: Mazzola S; Forni M; Albertini M; Bacci M L; Zannoni A; Gentilini F; Lavitrano M; Bach F H; Otterbein L E; Clement M G
Carbon monoxide pretreatment prevents respiratory derangement and ameliorates hyperacute endotoxic shock in pigs.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):2045-7.
2005: Ollinger Robert; Bilban Martin; Erat Anna; Froio Alberto; McDaid James; Tyagi Shivraj; Csizmadia Eva; Graça-Souza Aurelio V; Liloia Angela; Soares Miguel P; Otterbein Leo E; Usheva Anny; Yamashita Kenichiro; Bach Fritz H
Bilirubin: a natural inhibitor of vascular smooth muscle cell proliferation.
Circulation 2005;112(7):1030-9.
2005: Bach Fritz H
Heme oxygenase-1: a therapeutic amplification funnel.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1216-9.
2005: Wang Hongjun; Lee Soo Sun; Gao Wenda; Czismadia Eva; McDaid James; Ollinger Robert; Soares Miguel P; Yamashita Kenichiro; Bach Fritz H
Donor treatment with carbon monoxide can yield islet allograft survival and tolerance.
Diabetes 2005;54(5):1400-6.
2005: Berberat Pascal O; A-Rahim Yousif I; Yamashita Kenichiro; Warny Michel M; Csizmadia Eva; Robson Simon C; Bach Fritz H
Heme oxygenase-1-generated biliverdin ameliorates experimental murine colitis.
Inflammatory bowel diseases 2005;11(4):350-9.
2005: McDaid James; Yamashita Kenichiro; Chora Angelo; Ollinger Robert; Strom Terry B; Li Xian C; Bach Fritz H; Soares Miguel P
Heme oxygenase-1 modulates the allo-immune response by promoting activation-induced cell death of T cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):458-60.
2005: Nakao Atsunori; Neto Joao Seda; Kanno Shinichi; Stolz Donna B; Kimizuka Kei; Liu Fang; Bach Fritz H; Billiar Timothy R; Choi Augustine Mk; Otterbein Leo E; Murase Noriko
Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(2):282-91.
2004: Fondevila Constantino; Shen Xiu-Da; Tsuchiyashi Seiichiro; Yamashita Kenichiro; Csizmadia Eva; Lassman Charles; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Bach Fritz H
Biliverdin therapy protects rat livers from ischemia and reperfusion injury.
Hepatology (Baltimore, Md.) 2004;40(6):1333-41.
2004: Nakao Atsunori; Otterbein Leo E; Overhaus Marcus; Sarady Judit K; Tsung Allan; Kimizuka Kei; Nalesnik Michael A; Kaizu Takashi; Uchiyama Takashi; Liu Fang; Murase Noriko; Bauer Anthony J; Bach Fritz H
Biliverdin protects the functional integrity of a transplanted syngeneic small bowel.
Gastroenterology 2004;127(2):595-606.
2004: Lavitrano Marialuisa; Smolenski Ryszard T; Musumeci Antonino; Maccherini Massimo; Slominska Ewa; Di Florio Ernesto; Bracco Adele; Mancini Antonio; Stassi Giorgio; Patti Mariella; Giovannoni Roberto; Froio Alberto; Simeone Felicetta; Forni Monica; Bacci Maria Laura; D'Alise Giuseppe; Cozzi Emanuele; Otterbein Leo E; Yacoub Magdi H; Bach Fritz H; Calise Fulvio
Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(10):1093-5.
2004: Akamatsu Yorihiro; Haga Manabu; Tyagi Shivraj; Yamashita Kenichiro; Graça-Souza Aurelio Vicente; Ollinger Robert; Czismadia Eva; May G Aaron; Ifedigbo Emeka; Otterbein Leo E; Bach Fritz H; Soares Miguel P
Heme oxygenase-1-derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(6):771-2.
2004: Yamashita Kenichiro; McDaid James; Ollinger Robert; Tsui Tung-Yu; Berberat Pascal O; Usheva Anny; Csizmadia Eva; Smith R Neal; Soares Miguel P; Bach Fritz H
Biliverdin, a natural product of heme catabolism, induces tolerance to cardiac allografts.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(6):765-7.
2004: Soares Miguel P; Seldon Mark P; Gregoire Isabel Pombo; Vassilevskaia Tatiana; Berberat Pascal O; Yu Jia; Tsui Tung-Yu; Bach Fritz H
Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3553-63.
2003: Zuckerbraun Brian S; Billiar Timothy R; Otterbein Sherrie L; Kim Peter K M; Liu Fang; Choi Augustine M K; Bach Fritz H; Otterbein Leo E
Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1.
The Journal of experimental medicine 2003;198(11):1707-16.
2003: Berberat P O; Katori M; Kaczmarek E; Anselmo D; Lassman C; Ke B; Shen X; Busuttil R W; Yamashita Kenichiro; Csizmadia Eva; Tyagi Shivraj; Otterbein Leo E; Brouard S; Tobiasch E; Bach F H; Kupiec-Weglinski J W; Soares M P
Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1724-6.
2003: Nakao A; Moore B A; Murase N; Liu F; Zuckerbraun B S; Bach F H; Choi A M K; Nalesnik M A; Otterbein L E; Bauer A J
Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility.
Gut 2003;52(9):1278-85.
2003: Fondevila C; Katori M; Lassman C; Carmody I; Busuttil R W; Bach F H; Kupiec-Weglinski J W
Biliverdin protects rat livers from ischemia/reperfusion injury.
Transplantation proceedings 2003;35(5):1798-9.
2003: Otterbein Leo E; Soares Miguel P; Yamashita Kenichiro; Bach Fritz H
Heme oxygenase-1: unleashing the protective properties of heme.
Trends in immunology 2003;24(8):449-55.
2003: Otterbein Leo E; Zuckerbraun Brian S; Haga Manabu; Liu Fang; Song Ruiping; Usheva Anny; Stachulak Christina; Bodyak Natalya; Smith R Neal; Csizmadia Eva; Tyagi Shivraj; Akamatsu Yorihiro; Flavell Richard J; Billiar Timothy R; Tzeng Edith; Bach Fritz H; Choi Augustine M K; Soares Miguel P
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury.
Nature medicine 2003;9(2):183-90.
2002: Wang Ning; Lee Jang Ming; Tobiasch Edda; Csizmadia Eva; Smith Neal R; Gollackes Bend; Robson Simon C; Bach Fritz H; Lin Yuan
Induction of xenograft accommodation by modulation of elicited antibody responses1 2.
Transplantation 2002;74(3):334-45.
2002: Ivinson Adrian J; Bach Fritz H
The xenotransplantation question: public consultation is an important part of the answer.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2002;167(1):42-3.
2002: Brouard Sophie; Berberat Pascal O; Tobiasch Edda; Seldon Mark P; Bach Fritz H; Soares Miguel P
Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis.
The Journal of biological chemistry 2002;277(20):17950-61.
2002: Soares Miguel P; Usheva Anny; Brouard Sophie; Berberat Pascal O; Gunther Lukas; Tobiasch Edda; Bach Fritz H
Modulation of endothelial cell apoptosis by heme oxygenase-1-derived carbon monoxide.
Antioxidants & redox signaling 2002;4(2):321-9.
2002: Günther Lukas; Berberat Pascal O; Haga Manabu; Brouard Sophie; Smith R Neal; Soares Miguel P; Bach Fritz H; Tobiasch Edda
Carbon monoxide protects pancreatic beta-cells from apoptosis and improves islet function/survival after transplantation.
Diabetes 2002;51(4):994-9.
2002: Bach Fritz H; Ivinson Adrian J
A shrewd and ethical approach to xenotransplantation.
Trends in biotechnology 2002;20(3):129-31.
2002: Bach Fritz H
Heme oxygenase-1 as a protective gene.
Wiener klinische Wochenschrift 2002;114 Suppl 4():1-3.
2001: Soares M P; Brouard S; Smith R N; Bach F H
Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs.
Immunological reviews 2001;184():275-85.
2001: Tobiasch E; Günther L; Bach F H
Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(6):566-71.
2001: Sato K; Balla J; Otterbein L; Smith R N; Brouard S; Lin Y; Csizmadia E; Sevigny J; Robson S C; Vercellotti G; Choi A M; Bach F H; Soares M P
Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):4185-94.
2001: Wang N; Lee J M; Soares M P; Csizmadia E; Xu D; Liew F Y; Smith N; Bach F H; Lin Y
TH2 cytokines regulate gene expression and proinflammatory responses in xenografts.
Transplantation proceedings 2001;33(1-2):776-7.
2001: Wang N; Lee J M; Soares M P; Csizmadia E; Robson S C; Smith N; Bach F H; Lin Y
Long-term survival of hamster hearts in presensitized rats.
Transplantation proceedings 2001;33(1-2):747-8.
2001: Grey S T; Lock J; Bach F H; Ferran C
Adenovirus-mediated gene transfer of A20 in murine islets inhibits Fas-induced apoptosis.
Transplantation proceedings 2001;33(1-2):577-8.
2000: Brouard S; Otterbein L E; Anrather J; Tobiasch E; Bach F H; Choi A M; Soares M P
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis.
The Journal of experimental medicine 2000;192(7):1015-26.
2000: Imai M; Takigami K; Guckelberger O; Kaczmarek E; Csizmadia E; Bach F H; Robson S C
Recombinant adenoviral mediated CD39 gene transfer prolongs cardiac xenograft survival.
Transplantation 2000;70(6):864-70.
2000: Imai M; Takigami K; Guckelberger O; Lin Y; Sevigny J; Kaczmarek E; Goepfert C; Enjyoji K; Bach F H; Rosenberg R D; Robson S C
CD39/vascular ATP diphosphohydrolase modulates xenograft survival.
Transplantation proceedings 2000;32(5):969.
2000: Lin Y; Soares M P; Sato K; Csizmadia E; Robson S C; Smith N; Bach F H
Long-term survival of hamster hearts in presensitized rats.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4883-92.
1999: Imai M; Takigami K; Guckelberger O; Enjyoji K; Smith R N; Lin Y; Csizmadia E; Sévigny J; Rosenberg R D; Bach F H; Robson S C
Modulation of nucleoside [correction of nucleotide] triphosphate diphosphohydrolase-1 (NTPDase-1)cd39 in xenograft rejection.
Molecular medicine (Cambridge, Mass.) 1999;5(11):743-52.
1999: Grey S T; Arvelo M B; Hasenkamp W; Bach F H; Ferran C
A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets.
The Journal of experimental medicine 1999;190(8):1135-46.
1999: Soares M P; Lin Y; Sato K; Stuhlmeier K M; Bach F H
Accommodation.
Immunology today 1999;20(10):434-7.
1999: Sato K; Takigami K; Miyatake T; Czismadia E; Latinne D; Bazin H; Bach F H; Soares M P
Suppression of delayed xenograft rejection by specific depletion of elicited antibodies of the IgM isotype.
Transplantation 1999;68(6):844-54.
1999: Lin Y; Soares M P; Sato K; Takigami K; Csizmadia E; Smith N; Bach F H
Accommodated xenografts survive in the presence of anti-donor antibodies and complement that precipitate rejection of naive xenografts.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2850-7.
1999: Robson S C; Schulte am Esch J; Bach F H
Factors in xenograft rejection.
Annals of the New York Academy of Sciences 1999;875():261-76.
1999: Bach F H; Soares M; Lin Y; Ferran C
Barriers to xenotransplantation.
Transplantation proceedings 1999;31(4):1819-20.
1999: Stroka D M; Badrichani A Z; Bach F H; Ferran C
Overexpression of A1, an NF-kappaB-inducible anti-apoptotic bcl gene, inhibits endothelial cell activation.
Blood 1999;93(11):3803-10.
1999: Lin Y; Soares M P; Sato K; Takigami K; Csizmadia E; Anrather J; Bach F H
Rejection of hamster cardiac xenografts by rat CD4+ or CD8+ T cells.
Transplantation proceedings 1999;31(1-2):959-60.
1999: Arvelo M B; Badrichani A Z; Stroka D M; Grey S T; Bach F H; Ferran C
A novel function for A20 in smooth muscle cells: inhibition of activation and proliferation.
Transplantation proceedings 1999;31(1-2):858-9.
1999: Grey S T; Arvelo M B; Hasenkamp W M; Bach F H; Ferran C
Adenovirus-mediated gene transfer of the anti-apoptotic protein A20 in rodent islets inhibits IL-1 beta-induced NO release.
Transplantation proceedings 1999;31(1-2):789.
1999: Bach F H
Medawar Prize Lecture. The intimate relationship of the MHC with T lymphocytes.
Transplantation proceedings 1999;31(1-2):51-6.
1999: Badrichani A Z; Stroka D M; Bilbao G; Curiel D T; Bach F H; Ferran C
Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-kappaB.
The Journal of clinical investigation 1999;103(4):543-53.
1999: Lin Y; Soares M P; Sato K; Takigami K; Csizmadia E; Anrather J; Bach F H
Rejection of cardiac xenografts by CD4+ or CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):1206-14.
1998: von Albertini M; Ferran C; Brostjan C; Bach F H; Goodman D J
Membrane-associated lymphotoxin on natural killer cells activates endothelial cells via an NF-kappaB-dependent pathway.
Transplantation 1998;66(9):1211-9.
1998: Tran T H; Grey S; Anrather J; Steinhäuslin F; Bach F H; Winkler H
Regulated and endothelial cell-specific expression of Fas ligand: an in vitro model for a strategy aiming at inhibiting xenograft rejection.
Transplantation 1998;66(9):1126-31.
1998: Soares M P; Muniappan A; Kaczmarek E; Koziak K; Wrighton C J; Steinhäuslin F; Ferran C; Winkler H; Bach F H; Anrather J
Adenovirus-mediated expression of a dominant negative mutant of p65/RelA inhibits proinflammatory gene expression in endothelial cells without sensitizing to apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4572-82.
1998: Soares M P; Lin Y; Anrather J; Csizmadia E; Takigami K; Sato K; Grey S T; Colvin R B; Choi A M; Poss K D; Bach F H
Expression of heme oxygenase-1 can determine cardiac xenograft survival.
Nature medicine 1998;4(9):1073-7.
1998: Kopp C W; Grey S T; Siegel J B; McShea A; Vetr H; Wrighton C J; Schulte am Esch J; Bach F H; Robson S C
Expression of human thrombomodulin cofactor activity in porcine endothelial cells.
Transplantation 1998;66(2):244-51.
1998: Miyatake T; Koyamada N; Hancock W W; Soares M P; Bach F H
Survival of accommodated cardiac xenografts upon retransplantation into cyclosporine-treated recipients.
Transplantation 1998;65(12):1563-9.
1998: Koyamada N; Miyatake T; Candinas D; Mark W; Hechenleitner P; Hancock W W; Soares M P; Bach F H
Transient complement inhibition plus T-cell immunosuppression induces long-term survival of mouse-to-rat cardiac xenografts.
Transplantation 1998;65(9):1210-5.
1998: Miyatake T; Sato K; Takigami K; Koyamada N; Hancock W W; Bazin H; Latinne D; Bach F H; Soares M P
Complement-fixing elicited antibodies are a major component in the pathogenesis of xenograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):4114-23.
1998: Ferran C; Stroka D M; Badrichani A Z; Cooper J T; Wrighton C J; Soares M; Grey S T; Bach F H
A20 inhibits NF-kappaB activation in endothelial cells without sensitizing to tumor necrosis factor-mediated apoptosis.
Blood 1998;91(7):2249-58.
1998: Kopp C W; Robson S C; Siegel J B; Anrather J; Winkler H; Grey S; Kaczmarek E; Bach F H; Geczy C L
Regulation of monocyte tissue factor activity by allogeneic and xenogeneic endothelial cells.
Thrombosis and haemostasis 1998;79(3):529-38.
1998: Bach F H; Fishman J A; Daniels N; Proimos J; Anderson B; Carpenter C B; Forrow L; Robson S C; Fineberg H V
Uncertainty in xenotransplantation: individual benefit versus collective risk.
Nature medicine 1998;4(2):141-4.
1997: Anrather D; Millan M T; Palmetshofer A; Robson S C; Geczy C; Ritchie A J; Bach F H; Ewenstein B M
Thrombin activates nuclear factor-kappaB and potentiates endothelial cell activation by TNF.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5620-8.
1997: Bach F H
Some problems related to discordant xenografting.
Transplantation proceedings 1997;29(7):3009-10.
1997: Bach F H
Genetic engineering as an approach to xenotransplantation.
World journal of surgery 1997;21(9):913-6.
1997: Bach F H
D. Bernard Amos: humanist, scientist and friend.
Human immunology 1997;57(1):51-3.
1997: Siegel J B; Grey S T; Lesnikoski B A; Kopp C W; Soares M; Schulte am Esch J; Bach F H; Robson S C
Xenogeneic endothelial cells activate human prothrombin.
Transplantation 1997;64(6):888-96.
1997: Hancock W W; Miyatake T; Koyamada N; Kut J P; Soares M; Russell M E; Bach F H; Sayegh M H
Effects of leflunomide and deoxyspergualin in the guinea pig-->rat cardiac model of delayed xenograft rejection: suppression of B cell and C-C chemokine responses but not induction of macrophage lectin.
Transplantation 1997;64(5):696-704.
1997: Stuhlmeier K M; Kao J J; Bach F H
Arachidonic acid influences proinflammatory gene induction by stabilizing the inhibitor-kappaBalpha/nuclear factor-kappaB (NF-kappaB) complex, thus suppressing the nuclear translocation of NF-kappaB.
The Journal of biological chemistry 1997;272(39):24679-83.
1997: Bach F H
Xenotransplantation: a possible option for the future.
Transplantation proceedings 1997;29(6):2651-2.
1997: Bach F H; Ferran C; Soares M; Wrighton C J; Anrather J; Winkler H; Robson S C; Hancock W W
Modification of vascular responses in xenotransplantation: inflammation and apoptosis.
Nature medicine 1997;3(9):944-8.
1997: Stuhlmeier K M; Tarn C; Bach F H
The effect of 5,8,11,14-eicosatetraynoic acid on endothelial cell gene expression.
European journal of pharmacology 1997;325(2-3):209-19.
1997: Kopp C W; Siegel J B; Hancock W W; Anrather J; Winkler H; Geczy C L; Kaczmarek E; Bach F H; Robson S C
Effect of porcine endothelial tissue factor pathway inhibitor on human coagulation factors.
Transplantation 1997;63(5):749-58.
1997: Stroka D M; Cooper J T; Brostjan C; Millan M T; Goodman D J; Wrighton C J; Bach F H; Ferran C
Expression of a negative dominant mutant of human p55 tumor necrosis factor-receptor inhibits TNF and monocyte-induced activation in porcine aortic endothelial cells.
Transplantation proceedings 1997;29(1-2):882.
1997: Cooper J T; Stroka D M; Brostjan C; Palmetshofer A; Bach F H; Ferran C
A20 expression inhibits endothelial cell activation.
Transplantation proceedings 1997;29(1-2):881.
1997: Ferran C; Stroka D M; Badrichani A Z; Cooper J T; Bach F H
Adenovirus-mediated gene transfer of A20 renders endothelial cells resistant to activation: a means of evaluating the role of endothelial cell activation in xenograft rejection.
Transplantation proceedings 1997;29(1-2):879-80.
1997: von Albertini M A; Stroka D M; Brostjan C; Stuhlmeier K M; Bach F H; Robson S C
Adenosine nucleotides induce E-selectin expression in porcine endothelial cells.
Transplantation proceedings 1997;29(1-2):1062.
1997: Bach F H; Ferran C; Candinas D; Miyatake T; Koyamada N; Mark W; Hechenleitner P; Hancock W W
Accommodation of xenografts: expression of "protective genes" in endothelial and smooth muscle cells.
Transplantation proceedings 1997;29(1-2):56-8.
1997: Anrather J; Csizmadia V; Brostjan C; Soares M P; Bach F H; Winkler H
Inhibition of bovine endothelial cell activation in vitro by regulated expression of a transdominant inhibitor of NF-kappa B.
The Journal of clinical investigation 1997;99(4):763-72.
1997: Millan M T; Geczy C; Stuhlmeier K M; Goodman D J; Ferran C; Bach F H
Human monocytes activate porcine endothelial cells, resulting in increased E-selectin, interleukin-8, monocyte chemotactic protein-1, and plasminogen activator inhibitor-type-1 expression.
Transplantation 1997;63(3):421-9.
1997: Bach F H; Ferran C; Hechenleitner P; Mark W; Koyamada N; Miyatake T; Winkler H; Badrichani A; Candinas D; Hancock W W
Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment.
Nature medicine 1997;3(2):196-204.
1997: Robson S C; Daoud S; Bégin M; Côté Y P; Siegel J B; Bach F H; Beaudoin A R
Modulation of vascular ATP diphosphohydrolase by fatty acids.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1997;8(1):21-7.
1997: Robson S C; Kaczmarek E; Siegel J B; Candinas D; Koziak K; Millan M; Hancock W W; Bach F H
Loss of ATP diphosphohydrolase activity with endothelial cell activation.
The Journal of experimental medicine 1997;185(1):153-63.
1997: Ferran C; Badrichani A Z; Cooper J T; Stroka D M; Bach F H
Xenotransplantation: progress toward clinical development.
Advances in nephrology from the Necker Hospital 1997;27():391-420.
1996: Candinas D; Belliveau S; Koyamada N; Miyatake T; Hechenleitner P; Mark W; Bach F H; Hancock W W
T cell independence of macrophage and natural killer cell infiltration, cytokine production, and endothelial activation during delayed xenograft rejection.
Transplantation 1996;62(12):1920-7.
1996: Koyamada N; Miyatake T; Candinas D; Hechenleitner P; Siegel J; Hancock W W; Bach F H; Robson S C
Apyrase administration prolongs discordant xenograft survival.
Transplantation 1996;62(12):1739-43.
1996: Kaczmarek E; Koziak K; Sévigny J; Siegel J B; Anrather J; Beaudoin A R; Bach F H; Robson S C
Identification and characterization of CD39/vascular ATP diphosphohydrolase.
The Journal of biological chemistry 1996;271(51):33116-22.
1996: Candinas D; Koyamada N; Miyatake T; Siegel J; Hancock W W; Bach F H; Robson S C
Loss of rat glomerular ATP diphosphohydrolase activity during reperfusion injury is associated with oxidative stress reactions.
Thrombosis and haemostasis 1996;76(5):807-12.
1996: Winkler H; Brostjan C; Csizmadia V; Natarajan G; Anrather J; Bach F H
The intron-exon structure of the porcine E-selectin-encoding gene.
Gene 1996;176(1-2):67-72.
1996: Goodman D J; von Albertini M A; McShea A; Wrighton C J; Bach F H
Adenoviral-mediated overexpression of I(kappa)B(alpha) in endothelial cells inhibits natural killer cell-mediated endothelial cell activation.
Transplantation 1996;62(7):967-72.
1996: Bach F H; Winkler H; Ferran C; Hancock W W; Robson S C
Delayed xenograft rejection.
Immunology today 1996;17(8):379-84.
1996: Candinas D; Lesnikoski B A; Robson S C; Miyatake T; Scesney S M; Marsh H C; Ryan U S; Dalmasso A P; Hancock W W; Bach F H
Effect of repetitive high-dose treatment with soluble complement receptor type 1 and cobra venom factor on discordant xenograft survival.
Transplantation 1996;62(3):336-42.
1996: Brostjan C; Anrather J; Csizmadia V; Stroka D; Soares M; Bach F H; Winkler H
Glucocorticoid-mediated repression of NFkappaB activity in endothelial cells does not involve induction of IkappaBalpha synthesis.
The Journal of biological chemistry 1996;271(32):19612-6.
1996: Stuhlmeier K M; Tarn C; Csizmadia V; Bach F H
Selective suppression of endothelial cell activation by arachidonic acid.
European journal of immunology 1996;26(7):1417-23.
1996: Candinas D; Lesnikoski B A; Hancock W W; Otsu I; Koyamada N; Dalmasso A P; Robson S C; Bach F H
Inhibition of platelet integrin GPIIbIIIa prolongs survival of discordant cardiac xenografts.
Transplantation 1996;62(1):1-5.
1996: Cooper J T; Stroka D M; Brostjan C; Palmetshofer A; Bach F H; Ferran C
A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism.
The Journal of biological chemistry 1996;271(30):18068-73.
1996: Robson S C; Candinas D; Winkler H; Kopp C; Hancock W W; Bach F H
Immunobiology of discordant xenograft rejection and potential therapeutic modalities.
Transplantation proceedings 1996;28(3):1154-5.
1996: Kapetanopoulos A; Vanhove B; Bach F H; de Martin R
Localization of the human mitogen-induced GTP-binding protein gem to chromosome 8q22.3.
Genomics 1996;33(3):537-8.
1996: Lesnikoski B A; Candinas D; Hancock W W; Otsu I; Siegel J; Bach F H; Robson S C
Inhibition of platelet GPIIbIIIa prolongs survival of discordant cardiac xenografts.
Transplantation proceedings 1996;28(2):703.
1996: Candinas D; Bach F H; Hancock W W
Delayed xenograft rejection in complement-depleted T-cell-deficient rat recipients of guinea pig cardiac grafts.
Transplantation proceedings 1996;28(2):678.
1996: Brostjan C; Anrather J; Csizmadia V; Natarajan G; Bach F H; Winkler H
Deletion analysis of the porcine E-selectin promoter.
Transplantation proceedings 1996;28(2):639-41.
1996: Ferran C; Cooper J T; Brostjan C; Stroka D M; Millan M T; Goodman D J; Bach F H
Expression of a truncated form of the human p55 TNF-receptor in bovine aortic endothelial cells renders them resistant to human TNF.
Transplantation proceedings 1996;28(2):618-9.
1996: Goodman D J; von Albertini M; Bach F H
Human natural killer cells induce expression of E-selectin and interleukin-8 mRNA in porcine endothelial cells.
Transplantation proceedings 1996;28(2):609.
1996: von Albertini M A; Goodman D J; Bach F H
Direct cell contact is required to induce expression of E-selectin and IL-8 secretion in pig endothelial cells by human natural killer cells.
Transplantation proceedings 1996;28(2):608.
1996: Candinas D; Lesnikoski B A; Robson S C; Scesney S M; Otsu I; Myiatake T; Marsh H C; Ryan U S; Hancock W W; Bach F H
Soluble complement receptor type 1 and cobra venom factor in discordant xenotransplantation.
Transplantation proceedings 1996;28(2):581.
1996: Robson S C; Candinas D; Siegel J B; Kopp C; Millan M; Hancock W W; Bach F H
Potential mechanism of abnormal thromboregulation in xenograft rejection: loss of ecto-ATPases upon endothelial cell activation.
Transplantation proceedings 1996;28(2):536.
1996: Wrighton C J; Hofer-Warbinek R; Moll T; Eytner R; Bach F H; de Martin R
Inhibition of endothelial cell activation by adenovirus-mediated expression of I kappa B alpha, an inhibitor of the transcription factor NF-kappa B.
The Journal of experimental medicine 1996;183(3):1013-22.
1996: Robson S C; Young V K; Cook N S; Metternich R; Kasper-Konig W; Lesnikoski B A; Pierson R N; Hancock W W; Candinas D; White D J; Bach F H
Thrombin inhibition in an ex vivo model of porcine heart xenograft hyperacute rejection.
Transplantation 1996;61(6):862-8.
1996: Goodman D J; Von Albertini M; Willson A; Millan M T; Bach F H
Direct activation of porcine endothelial cells by human natural killer cells.
Transplantation 1996;61(5):763-71.
1996: Bach F H; Robson S C; Wrighton C J; Stuhlmeier K; Ferran C; Winkler H
Genetic engineering of endothelial cells to ameliorate xenograft rejection.
Clinical transplantation 1996;10(1 Pt 2):124-7.
1996: Bach F H; Winkler H; Wrighton C J; Robson S C; Stuhlmeier K; Ferran C
Xenotransplantation: a possible solution to the shortage of donor organs.
Transplantation proceedings 1996;28(1):416-7.
1995: Düchler M; Offterdinger M; Holzmüller H; Lipp J; Chu C T; Aschauer B; Bach F H; Hofer E
NKG2-C is a receptor on human natural killer cells that recognizes structures on K562 target cells.
European journal of immunology 1995;25(10):2923-31.
1995: Bach F H; Robson S C; Winkler H; Ferran C; Stuhlmeier K M; Wrighton C J; Hancock W W
Barriers to xenotransplantation.
Nature medicine 1995;1(9):869-73.
1995: Ferran C; Millan M T; Csizmadia V; Cooper J T; Brostjan C; Bach F H; Winkler H
Inhibition of NF-kappa B by pyrrolidine dithiocarbamate blocks endothelial cell activation.
Biochemical and biophysical research communications 1995;214(1):212-23.
1995: Robson S C; Candinas D; Hancock W W; Wrighton C; Winkler H; Bach F H
Role of endothelial cells in transplantation.
International archives of allergy and immunology 1995;106(4):305-22.
1995: Bach F H; Robson S C; Ferran C; Millan M; Anrather J; Kopp C; Lesnikoski B; Goodman D J; Hancock W W; Wrighton C
Xenotransplantation: endothelial cell activation and beyond.
Transplantation proceedings 1995;27(1):77-9.
1995: Lesnikoski B A; Shaffer D A; Van der Werf W J; Dalmasso A P; Soares M P; Latinne D; Bazin H; Hancock W W; Bach F H
Endothelial and host mononuclear cell activation and cytokine expression during rejection of pig-to-baboon discordant xenografts.
Transplantation proceedings 1995;27(1):290-1.
1995: Wrighton C J; Kopp C W; McShea A; Vetr H; Bach F H
High-level expression of functional human thrombomodulin in cultured porcine aortic endothelial cells.
Transplantation proceedings 1995;27(1):288-9.
1995: Soares M; Havaux X; Van Beneden R; Van der Werf W J; Bach F H; Bazin H; Latinne D
Characterisation of rat anti-guinea pig circulating xenoreactive natural antibodies and secreting cells.
Transplantation proceedings 1995;27(1):282-5.
1995: Moll T; Czyz M; Holzmüller H; Hofer-Warbinek R; Wagner E; Winkler H; Bach F H; Hofer E
Regulation of the tissue factor promoter in endothelial cells. Binding of NF kappa B-, AP-1-, and Sp1-like transcription factors.
The Journal of biological chemistry 1995;270(8):3849-57.
1995: de Martin R; Holzmüller H; Hofer E; Bach F H
Intron-exon structure of the porcine I kappa B alpha-encoding gene.
Gene 1995;152(2):253-5.
1994: Millan M T; Ferran C; Winkler H; Blakely M L; van der Werf W J; Hancock W W; Bach F H
Xenotransplantation: problems and approaches.
Transplantation proceedings 1994;26(6):3593-6.
1994: Blakely M L; Van der Werf W J; Berndt M C; Dalmasso A P; Bach F H; Hancock W W
Activation of intragraft endothelial and mononuclear cells during discordant xenograft rejection.
Transplantation 1994;58(10):1059-66.
1994: Latinne D; Soares M; Havaux X; Cormont F; Lesnikoski B; Bach F H; Bazin H
Depletion of IgM xenoreactive natural antibodies by injection of anti-mu monoclonal antibodies.
Immunological reviews 1994;141():95-125.
1994: Bach F H; Robson S C; Ferran C; Winkler H; Millan M T; Stuhlmeier K M; Vanhove B; Blakely M L; van der Werf W J; Hofer E
Endothelial cell activation and thromboregulation during xenograft rejection.
Immunological reviews 1994;141():5-30.
1994: Stuhlmeier K M; Csizmadia V; Cheng Q; Winkler H; Bach F H
Selective inhibition of E-selectin, ICAM-1, and VCAM in endothelial cells.
European journal of immunology 1994;24(9):2186-90.
1994: Blakely M L; Van der Werf W J; Dalmasso A P; Bach F H
Anti-B cell agents: suppression of natural antibodies and prolongation of survival in discordant xenografts.
Transplantation proceedings 1994;26(3):1374-5.
1994: Van der Werf W J; Blakely M L; Hancock W; Soares M; Latinne D; Bazin H; Bach F H
Sustained suppression of xenoreactive natural antibodies: anti-IgM monoclonal antibody and anti-B cell immunosuppressants.
Transplantation proceedings 1994;26(3):1372-3.
1994: Soares M; Nisol F; Bach F H; Bazin H; Latinne D
Use of anti-mu monoclonal antibody as a therapeutic approach to achieve depletion of xenoreactive natural antibodies.
Transplantation proceedings 1994;26(3):1357-9.
1994: Hofer E; Stuhlmeier K M; Blakely M L; Van der Werf W; Hancock W W; Hunt B J; Bach F H
Pathways of procoagulation in discordant xenografting.
Transplantation proceedings 1994;26(3):1322.
1994: Bach F H; Stuhlmeier K M; Vanhove B; Van der Werf W J; Blakely M L; de Martin R; Hancock W W; Winkler H
Endothelial cells in xenotransplantation: do they accommodate?
Transplantation proceedings 1994;26(3):1167-9.
1994: Stuhlmeier K M; Winkler H; Csizmadia V; Cheng Q; Bach F H
Selective inhibition of E-selectin expression by alpha-globulins.
Transplantation proceedings 1994;26(3):1321.
1994: Blakely M L; Van der Werf W J; Stuhlmeier K; Dalmasso A P; Winkler H; Bach F H
Retinoic acid inhibits expression of E-selectin in endothelial cells and prolongs discordant xenograft survival.
Transplantation proceedings 1994;26(3):1176.
1994: Cheng Q; Cant C A; Moll T; Hofer-Warbinek R; Wagner E; Birnstiel M L; Bach F H; de Martin R
NK-kappa B subunit-specific regulation of the I kappa B alpha promoter.
The Journal of biological chemistry 1994;269(18):13551-7.
1994: Bach F H; Blakely M L; Van der Werf W J; Vanhove B; Stuhlmeier K; de Martin R; Winkler H
Xenotransplantation: problems posed by endothelial cell activation.
Transplantation proceedings 1994;26(2):1029-30.
1994: Soares M; Lu X; Havaux X; Baranski A; Reding R; Latinne D; Daha M; Lambotte L; Bach F H; Bazin H
In vivo IgM depletion by anti-mu monoclonal antibody therapy. The role of IgM in hyperacute vascular rejection of discordant xenografts.
Transplantation 1994;57(7):1003-9.
1994: Bach F H
The endothelial cell: an obstacle to xenografting.
Pathologie-biologie 1994;42(3):213-6.
1993: Soares M P; Latinne D; Elsen M; Figueroa J; Bach F H; Bazin H
In vivo depletion of xenoreactive natural antibodies with an anti-mu monoclonal antibody.
Transplantation 1993;56(6):1427-33.
1993: Vanhove B; Bach F H
Human xenoreactive natural antibodies--avidity and targets on porcine endothelial cells.
Transplantation 1993;56(5):1251-3.
1993: Hancock W W; Blakely M L; Van der Werf W; Bach F H
Rejection of guinea pig cardiac xenografts post-cobra venom factor therapy is associated with infiltration by mononuclear cells secreting interferon-gamma and diffuse endothelial activation.
Transplantation proceedings 1993;25(5):2932.
1993: de Martin R; Vanhove B; Cheng Q; Hofer E; Csizmadia V; Winkler H; Bach F H
Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B.
The EMBO journal 1993;12(7):2773-9.
1993: Bach F H
Xenotransplantation: a view to the future.
Transplantation proceedings 1993;25(1 Pt 1):25-9.
1992: Bach F H; Platt J L
Xenotransplantation: a view of issues.
Transplantation proceedings 1992;24(4 Suppl 2):49-52.
1990: Reinsmoen N L; Kaufman D; Matas A; Sutherland D E; Najarian J S; Bach F H
A new in vitro approach to determine acquired tolerance in long-term kidney allograft recipients.
Transplantation 1990;50(5):783-90.

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