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Fred Kadlubar

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Xuemei Zhang; Chunyang Fan; Maosheng Huang; Susan Kadlubar; Jie Lin; Baitang Ning; Xifeng Wu; Xinfeng Yu; Fred F Kadlubar
GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer.
Xuemei Zhang; Susan Kadlubar; Jie Lin; Zhongning Lin; Baitang Ning; Xifeng Wu; Fred F Kadlubar
Association between GSTM1 copy number, promoter variants and susceptibility to urinary bladder cancer.
Jianjun Zhang; Xuemei Zhang; Ishwori B Dhakal; Myron D Gross; Fred F Kadlubar; Kristin E Anderson
Sequence variants in antioxidant defense and DNA repair genes, dietary antioxidants, and pancreatic cancer risk.

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All Publications

2013: Xuemei Zhang; Chunyang Fan; Maosheng Huang; Susan Kadlubar; Jie Lin; Baitang Ning; Xifeng Wu; Xinfeng Yu; Fred F Kadlubar
GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer.
Pharmacogenomics and personalized medicine 2013;6():9-17.
2012: Xuemei Zhang; Susan Kadlubar; Jie Lin; Zhongning Lin; Baitang Ning; Xifeng Wu; Fred F Kadlubar
Association between GSTM1 copy number, promoter variants and susceptibility to urinary bladder cancer.
International journal of molecular epidemiology and genetics 2012;3(3):228-36.
2011: Jianjun Zhang; Xuemei Zhang; Ishwori B Dhakal; Myron D Gross; Fred F Kadlubar; Kristin E Anderson
Sequence variants in antioxidant defense and DNA repair genes, dietary antioxidants, and pancreatic cancer risk.
International journal of molecular epidemiology and genetics 2011;2(3):236-44.
2011: Dan Gu; Melissa M Raymundo; Fred F Kadlubar; Robert J Turesky
Ultraperformance liquid chromatography-tandem mass spectrometry method for biomonitoring cooked meat carcinogens and their metabolites in human urine.
Analytical chemistry 2011;83(3):1093-101.
2010: Xinfeng Yu; Ishwori B Dhakal; Marjorie Beggs; Vineetha Koroth Edavana; Suzanne Williams; Xuemei Zhang; Kelly Mercer; Baitang Ning; Nicholas P Lang; Fred F Kadlubar; Susan Kadlubar
Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity.
Toxicological sciences : an official journal of the Society of Toxicology 2010;118(2):391-403.
2010: Jianjun Zhang; Ishwori B Dhakal; Nicholas P Lang; Fred F Kadlubar
Polymorphisms in inflammatory genes, plasma antioxidants, and prostate cancer risk.
Cancer causes & control : CCC 2010;21(9):1437-44.
2010: Erin E Bessette; Simon Spivack; Angela K Goodenough; Tao Wang; Shailesh Pinto; Fred F Kadlubar; Robert J Turesky
Identification of carcinogen DNA adducts in human saliva by linear quadrupole ion trap/multistage tandem mass spectrometry.
Chemical research in toxicology 2010;23(7):1234-44.
2010: Dan Gu; Lynn McNaughton; David Lemaster; Brian G Lake; Nigel J Gooderham; Fred F Kadlubar; Robert J Turesky
A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
Chemical research in toxicology 2010;23(4):788-801.
2010: Jianjun Zhang; Ishwori B Dhakal; Graham Greene; Nicholas P Lang; Fred F Kadlubar
Polymorphisms in hOGG1 and XRCC1 and risk of prostate cancer: effects modified by plasma antioxidants.
Urology 2010;75(4):779-85.
2010: Kelly E Mercer; Eugene O Apostolov; Goncalo Gamboa da Costa; Xinfeng Yu; Patrick Lang; Dean W Roberts; Warren Davis; Alexei G Basnakian; Fred F Kadlubar; Susan A Kadlubar
Expression of sulfotransferase isoform 1A1 (SULT1A1) in breast cancer cells significantly increases 4-hydroxytamoxifen-induced apoptosis.
International journal of molecular epidemiology and genetics 2010;1(2):92-103.
2009: Jianjun Zhang; Ishwori B Dhakal; Myron D Gross; Nicholas P Lang; Fred F Kadlubar; Lisa J Harnack; Kristin E Anderson
Physical activity, diet, and pancreatic cancer: a population-based, case-control study in Minnesota.
Nutrition and cancer 2009;61(4):457-65.
2009: Susan Kadlubar; Jeffrey P Anderson; Carol Sweeney; Myron D Gross; Nicholas P Lang; Fred F Kadlubar; Kristin E Anderson
Phenotypic CYP2A6 variation and the risk of pancreatic cancer.
JOP : Journal of the pancreas 2009;10(3):263-70.
2008: Takatsugu Mizumachi; Levan Muskhelishvili; Akihiro Naito; Jun Furusawa; Chun-Yang Fan; Eric Siegel; Fred F Kadlubar; Udaya Kumar; Masahiro Higuchi
Increased distributional variance of mitochondrial DNA content associated with prostate cancer cells as compared with normal prostate cells.
The Prostate 2008;68(4):408-17.
2008: Rodney F Minchin; Aaron Lewis; Deanne Mitchell; Fred F Kadlubar; Michael E McManus
Sulfotransferase 4A1.
The international journal of biochemistry & cell biology 2008;40(12):2686-91.
2008: Zhongning Lin; xuemei zhang; Jingsheng Tuo; Yongli Guo; Bridgett Green; Chi-Chao Chan; Wen Tan; Ying Huang; Wenhua Ling; Fred F Kadlubar; Dongxin Lin; Baitang Ning
A variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer.
Human mutation 2008;29(1):113-22.
2007: Ruqing Liu; Paul E Blower; Anh-Nhan Pham; Jialong Fang; Zunyan Dai; Carolyn Wise; Bridgette Green; Candee H Teitel; Baitang Ning; Wenhua Ling; Beverly D Lyn-Cook; Fred F Kadlubar; Wolfgang Sadée; Ying Huang
Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin.
Molecular pharmacology 2007;72(6):1637-46.
2007: Tania Carreon; Fred F Kadlubar; Avima Ruder; Paul A Schulte; Richard B Hayes; Martha Waters; Delores J Grant; Robert Boissy; Douglas A Bell; George P Hemstreet; Songnian Yin; Grace K LeMasters; Nathaniel Rothman
Reply to the letter to the Editor: "N-Acetyltransferases and the susceptibility to benzidine-induced bladder carcinogenesis".
International journal of cancer. Journal international du cancer 2007;121(7):1637-9; author reply 1640-1.
2007: Fred F Kadlubar
Hormone-metabolizing genotypes: an alternate interpretation.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(9):1911.
2007: Christine B Ambrosone; Sara M Abrams; Katarzyna Gorlewska-Roberts; Fred F Kadlubar
Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells.
Archives of biochemistry and biophysics 2007;464(2):169-75.
2007: Mary H Ward; Amanda J Cross; Hozefa Divan; Martin Kulldorff; Susan Nowell-Kadlubar; Fred F Kadlubar; Rashmi Sinha
Processed meat intake, CYP2A6 activity and risk of colorectal adenoma.
Carcinogenesis 2007;28(6):1210-6.
2007: Carla J Gallagher; Fred F Kadlubar; Joshua Muscat; Christine B Ambrosone; Nicholas P Lang; Philip Lazarus
The UGT2B17 gene deletion polymorphism and risk of prostate cancer. A case-control study in Caucasians.
Cancer detection and prevention 2007;31(4):310-5.
2007: Jianjun Zhang; Ishwori Dhakal; Angie Stone; Baitang Ning; Graham Greene; Nicholas P Lang; Fred F Kadlubar
Plasma carotenoids and prostate cancer: a population-based case-control study in Arkansas.
Nutrition and cancer 2007;59(1):46-53.
2007: Jinsong Chen; Fred F Kadlubar; Junjian Z Chen
DNA supercoiling suppresses real-time PCR: a new approach to the quantification of mitochondrial DNA damage and repair.
Nucleic acids research 2007;35(4):1377-88.
2006: Miki Nakajima; Masahiro Itoh; Haruko Sakai; Tatsuki Fukami; Miki Katoh; Hiroshi Yamazaki; Fred F Kadlubar; Susumu Imaoka; Yoshihiko Funae; Tsuyoshi Yokoi
CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl.
International journal of cancer. Journal international du cancer 2006;119(11):2520-6.
2006: Jong Park; Lan Chen; Luke Ratnashinge; Thomas A Sellers; Jean-Paul Tanner; Ji-Hyun Lee; Nicole Dossett; Nicholas Lang; Fred F Kadlubar; Christine B Ambrosone; Babu Zachariah; Randy V Heysek; Stephen Patterson; Julio Pow-Sang
Deletion polymorphism of UDP-glucuronosyltransferase 2B17 and risk of prostate cancer in African American and Caucasian men.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(8):1473-8.
2006: Jingsheng Tuo; Baitang Ning; Christine M Bojanowski; Zhong-Ning Lin; Robert J Ross; George F Reed; Defen Shen; Xiaodong Jiao; Min Zhou; Emily Y Chew; Fred F Kadlubar; Chi-Chao Chan
Synergic effect of polymorphisms in ERCC6 5' flanking region and complement factor H on age-related macular degeneration predisposition.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9256-61.
2006: Jiyoung Ahn; Susan Nowell; Susan E McCann; Jihnhee Yu; Lisa Carter; Nicholas P Lang; Fred F Kadlubar; Luke D Ratnasinghe; Christine B Ambrosone
Associations between catalase phenotype and genotype: modification by epidemiologic factors.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(6):1217-22.
2006: Zhengwen Jiang; Nadine Dragin; Lucia F Jorge-Nebert; Martha V Martin; F Peter Guengerich; Eleni Aklillu; Magnus Ingelman-Sundberg; George J Hammons; Beverly D Lyn-Cook; Fred F Kadlubar; Shannon N Saldana; Michael Sorter; Alexander Vinks; Nassr Nassr; Oliver Von Richter; Li Jin; Daniel W Nebert
Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype.
Pharmacogenetics and genomics 2006;16(5):359-67.
2006: Tania Carreon; Avima Ruder; Paul A Schulte; Richard Hayes; Nathaniel Rothman; Martha Waters; Delores J Grant; Robert Boissy; Douglas A Bell; Fred F Kadlubar; George P Hemstreet; Songnian Yin; Grace K LeMasters
NAT2 slow acetylation and bladder cancer in workers exposed to benzidine.
International journal of cancer. Journal international du cancer 2006;118(1):161-8.
2005: Oscar A Di Paolo; Candee H Teitel; Susan Nowell; Brian F Coles; Fred F Kadlubar
Expression of cytochromes P450 and glutathione S-transferases in human prostate, and the potential for activation of heterocyclic amine carcinogens via acetyl-coA-, PAPS- and ATP-dependent pathways.
International journal of cancer. Journal international du cancer 2005;117(1):8-13.
2005: Kristin E Anderson; Fred F Kadlubar; Martin Kulldorff; Lisa Harnack; Myron Gross; Nicholas P Lang; Cheryl Barber; Nat Rothman; Rashmi Sinha
Dietary intake of heterocyclic amines and benzo(a)pyrene: associations with pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(9):2261-5.
2005: xuemei zhang; Xiaoping Miao; Wen Tan; Baitang Ning; Zhihua Liu; Yuan Hong; Wenguang Song; Yongli Guo; Xinyu Zhang; Yan Shen; Boqin Qiang; Fred F Kadlubar; Dongxin Lin
Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer.
Gastroenterology 2005;129(2):565-76.
2005: Jie Lin; Fred F Kadlubar; Margaret R Spitz; Hua Zhao; Xifeng Wu
A modified host cell reactivation assay to measure DNA repair capacity for removing 4-aminobiphenyl adducts: a pilot study of bladder cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(7):1832-6.
2005: Baitang Ning; Susan Nowell; Carol Sweeney; Christine B Ambrosone; Suzanne Williams; Xiaoping Miao; Gang Liang; Dongxin Lin; Angie Stone; D Luke Ratnasinghe; Mugimane G Manjanatha; Nicholas P Lang; Fred F Kadlubar
Common genetic polymorphisms in the 5'-flanking region of the SULT1A1 gene: haplotypes and their association with platelet enzymatic activity.
Pharmacogenetics and genomics 2005;15(7):465-73.
2005: Susan Nowell; Jiyoung Ahn; James M Rae; Joshua O Scheys; Andrew Trovato; Carol Sweeney; Stewart MacLeod; Fred F Kadlubar; Christine B Ambrosone
Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients.
Breast cancer research and treatment 2005;91(3):249-58.
2005: Angie Stone; Luke D Ratnasinghe; Ginny L Emerson; Rama Modali; Teresa A Lehman; Gail Runnells; Alindria Carroll; Weleetka Carter; Samuel Barnhart; Al A Rasheed; Graham Greene; Don E Johnson; Christine B Ambrosone; Fred F Kadlubar; Nicholas P Lang
CYP3A43 Pro(340)Ala polymorphism and prostate cancer risk in African Americans and Caucasians.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1257-61.
2005: Elaine Ricicki; John R Soglia; Candee Teitel; Robert Kane; Fred F Kadlubar; Paul Vouros
Detection and quantification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl adducts in human pancreas tissue using capillary liquid chromatography-microelectrospray mass spectrometry.
Chemical research in toxicology 2005;18(4):692-9.
2005: Susan Nowell; Bridgett Green; Yong Ming Tang; Rick Wiese; Fred F Kadlubar
Examination of human tissue cytosols for expression of sulfotransferase isoform 1A2 (SULT1A2) using a SULT1A2-specific antibody.
Molecular pharmacology 2005;67(2):394-9.
2005: Brian F Coles; Fred F Kadlubar
Human alpha class glutathione S-transferases: genetic polymorphism, expression, and susceptibility to disease.
Methods in enzymology 2005;401():9-42.
2005: Andrew C Scallet; Levan Muskhelishvili; William Slikker; Fred F Kadlubar
Sex differences in cytochrome P450 1B1, an estrogen-metabolizing enzyme, in the rhesus monkey telencephalon.
Journal of chemical neuroanatomy 2005;29(1):71-80.
2004: Katarzyna M Gorlewska-Roberts; Candee H Teitel; Jackson Lay; Dean W Roberts; Fred F Kadlubar
Lactoperoxidase-catalyzed activation of carcinogenic aromatic and heterocyclic amines.
Chemical research in toxicology 2004;17(12):1659-66.
2004: Mihi Yang; Brian F Coles; Neil E Caporaso; Yunhee Choi; Nicholas P Lang; Fred F Kadlubar
Lack of association between Caucasian lung cancer risk and O6-methylguanine-DNA methyltransferase-codon 178 genetic polymorphism.
Lung cancer (Amsterdam, Netherlands) 2004;44(3):281-6.
2004: Junjian Z Chen; Fred F Kadlubar
Mitochondrial mutagenesis and oxidative stress in human prostate cancer.
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews 2004;22(1):1-12.
2004: Timothy R Rebbeck; Christine B Ambrosone; Douglas A Bell; STEPHEN CHANOCK; Richard Hayes; Fred F Kadlubar; Duncan C Thomas
SNPs, haplotypes, and cancer: applications in molecular epidemiology.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(5):681-7.
2004: Donghak Kim; Fred F Kadlubar; Candee H Teitel; F Peter Guengerich
Formation and reduction of aryl and heterocyclic nitroso compounds and significance in the flux of hydroxylamines.
Chemical research in toxicology 2004;17(4):529-36.
2004: Susan Nowell; D Luke Ratnasinghe; Christine B Ambrosone; Suzanne Williams; Terri Teague-Ross; Lyndsey Trimble; Gail Runnels; Alindria Carrol; Bridgett Green; Angie Stone; Don Johnson; Graham Greene; Fred F Kadlubar; Nicholas P Lang
Association of SULT1A1 phenotype and genotype with prostate cancer risk in African-Americans and Caucasians.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(2):270-6.
2004: Wolfgang W Huber; Candee H Teitel; Brian F Coles; Roberta S King; Frederick W Wiese; Keith R Kaderlik; Daniel A Casciano; Joseph G Shaddock; Gerard J Mulder; Kenneth F Ilett; Fred F Kadlubar
Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
Environmental and molecular mutagenesis 2004;44(4):265-76.
2004: Baitang Ning; Charles Wang; Fabrice MOREL; Susan Nowell; D Luke Ratnasinghe; Waleetka Carter; Fred F Kadlubar; Brian F Coles
Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.
Pharmacogenetics 2004;14(1):35-44.
2003: Robert J Turesky; James P Freeman; Ricky D Holland; Daniel M Nestorick; Dwight W Miller; D Luke Ratnasinghe; Fred F Kadlubar
Identification of aminobiphenyl derivatives in commercial hair dyes.
Chemical research in toxicology 2003;16(9):1162-73.
2003: Junjian Z Chen; Neriman Gokden; Graham F Greene; Bridgett Green; Fred F Kadlubar
Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis.
Carcinogenesis 2003;24(9):1481-7.
2003: Junjian Z Chen; Fred F Kadlubar
A new clue to glaucoma pathogenesis.
The American journal of medicine 2003;114(8):697-8.
2003: Frederick W Wiese; Patricia A Thompson; James Warneke; Janine G Einspahr; David S Alberts; Fred F Kadlubar
Variation in cyclooxygenase expression levels within the colorectum.
Molecular carcinogenesis 2003;37(1):25-31.
2003: Beatrice Faraglia; Shu Yuan Chen; Marilie D Gammon; Yujing Zhang; Susan L Teitelbaum; Alfred I Neugut; Habibul Ahsan; Gail C Garbowski; Hanina Hibshoosh; Dongxin Lin; Fred F Kadlubar; Regina M Santella
Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke.
Carcinogenesis 2003;24(4):719-25.
2003: Fred F Kadlubar; Gertrud S Berkowitz; Robert R Delongchamp; Charles Wang; Bridgett L Green; George Tang; Jatinder Lamba; Erin Schuetz; Mary S Wolff
The CYP3A4*1B variant is related to the onset of puberty, a known risk factor for the development of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(4):327-31.
2003: Shioko Kimura; Mayumi Kawabe; Aiming Yu; Hideki Morishima; Pedro Fernandez-Salguero; George J Hammons; Jerrold M Ward; Fred F Kadlubar; Frank J Gonzalez
Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2.
Carcinogenesis 2003;24(3):583-7.
2003: Carol Sweeney; Christine B Ambrosone; Lija Joseph; Angie Stone; Laura F Hutchins; Fred F Kadlubar; Brian F Coles
Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment.
International journal of cancer. Journal international du cancer 2003;103(6):810-4.
2003: Dong-xin Lin; Patricia A Thompson; Candee Teitel; Jun-Shi Chen; Fred F Kadlubar
Direct reduction of N-acetoxy-PhIP by tea polyphenols: a possible mechanism for chemoprevention against PhIP-DNA adduct formation.
Mutation research 2003;523-524():193-200.
2003: B Amirimani; B Ning; Anne C Deitz; B L Weber; Fred F Kadlubar; Timothy R Rebbeck
Increased transcriptional activity of the CYP3A4*1B promoter variant.
Environmental and molecular mutagenesis 2003;42(4):299-305.
2003: Brian F Coles; Fred F Kadlubar
Detoxification of electrophilic compounds by glutathione S-transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs?
BioFactors (Oxford, England) 2003;17(1-4):115-30.
2003: Qingsu Xia; Ming W Chou; Fred F Kadlubar; Po C Chan; Peter P Fu
Human liver microsomal metabolism and DNA adduct formation of the tumorigenic pyrrolizidine alkaloid, riddelliine.
Chemical research in toxicology 2003;16(1):66-73.
2002: Carol Sweeney; Brian F Coles; Susan Nowell; Nicholas P Lang; Fred F Kadlubar
Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer.
Toxicology 2002;181-182():83-7.
2002: Junjian Z Chen; Neriman Gokden; Graham F Greene; Perkins Mukunyadzi; Fred F Kadlubar
Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection.
Cancer research 2002;62(22):6470-4.
2002: Linda S Von Tungeln; Ping Yi; Thomas J Bucci; Victor M Samokyszyn; Ming W Chou; Fred F Kadlubar; Peter P Fu
Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F(1) neonatal mouse.
Cancer letters 2002;185(1):13-9.
2002: Susan Nowell; Carol Sweeney; Maria Winters; Angie Stone; Nicholas P Lang; Laura F Hutchins; Fred F Kadlubar; Christine B Ambrosone
Association between sulfotransferase 1A1 genotype and survival of breast cancer patients receiving tamoxifen therapy.
Journal of the National Cancer Institute 2002;94(21):1635-40.
2002: Mihi Yang; Brian F Coles; Robert R Delongchamp; Nicholas P Lang; Fred F Kadlubar
Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue.
Lung cancer (Amsterdam, Netherlands) 2002;38(1):15-21.
2002: Kristin E Anderson; Rashmi Sinha; Martin Kulldorff; Myron Gross; Nicholas P Lang; Cheryl Barber; Lisa Harnack; Eugene P DiMagno; Robin Bliss; Fred F Kadlubar
Meat intake and cooking techniques: associations with pancreatic cancer.
Mutation research 2002;506-507():225-31.
2002: Susan Nowell; Brian F Coles; Rashmi Sinha; Stewart MacLeod; D Luke Ratnasinghe; Craig Stotts; Fred F Kadlubar; Christine B Ambrosone; Nicholas P Lang
Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk.
Mutation research 2002;506-507():175-85.
2002: Brian F Coles; Guanping Chen; Fred F Kadlubar; Anna Radominska-Pandya
Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individuals.
Archives of biochemistry and biophysics 2002;403(2):270-6.
2002: Xifeng Wu; Hua Zhao; Christopher I Amos; Sanjay Shete; Nimisha Makan; Waun Ki Hong; Fred F Kadlubar; Margaret R Spitz
p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity.
Journal of the National Cancer Institute 2002;94(9):681-90.
2002: Susan Nowell; Carol Sweeney; George Hammons; Fred F Kadlubar; Nicholas P Lang
CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(4):377-83.
2002: Naoko Ishibe; Rashmi Sinha; David W Hein; Martin Kulldorff; Paul T Strickland; Adrian J Fretland; Wong-Ho Chow; Fred F Kadlubar; Nicholas P Lang; Nathaniel Rothman
Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas.
Pharmacogenetics 2002;12(2):145-50.
2002: K Gorlewska-Roberts; B Green; Manal Y Fares; Christine B Ambrosone; Fred F Kadlubar
Carcinogen-DNA adducts in human breast epithelial cells.
Environmental and molecular mutagenesis 2002;39(2-3):184-92.
2002: Patricia A Thompson; David M DeMarini; Fred F Kadlubar; Gail Y McClure; Lance R Brooks; Bridgett L Green; Manal Y Fares; Angie Stone; P David Josephy; Christine B Ambrosone
Evidence for the presence of mutagenic arylamines in human breast milk and DNA adducts in exfoliated breast ductal epithelial cells.
Environmental and molecular mutagenesis 2002;39(2-3):134-42.
2001: Brian F Coles; Fabrice MOREL; C Rauch; Wolfgang W Huber; M Yang; Candee H Teitel; Bridgette Green; Nicholas P Lang; Fred F Kadlubar
Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression.
Pharmacogenetics 2001;11(8):663-9.
2001: Christine B Ambrosone; Carol Sweeney; Brian F Coles; PA Thompson; Gail Y McClure; S Korourian; Manal Y Fares; Angie Stone; Fred F Kadlubar; Laura F Hutchins
Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer.
Cancer research 2001;61(19):7130-5.
2001: Fred F Kadlubar
Concluding remarks: symposium on Genetic Susceptibility to Environmental Toxicants.
Mutation research 2001;482(1-2):111-3.
2001: Bernadette Schoket; G Papp; K Lévay; G Mracková; Fred F Kadlubar; I Vincze
Impact of metabolic genotypes on levels of biomarkers of genotoxic exposure.
Mutation research 2001;482(1-2):57-69.
2001: Brian F Coles; Susan Nowell; Stewart MacLeod; C Sweeney; Nicholas P Lang; Fred F Kadlubar
The role of human glutathione S-transferases (hGSTs) in the detoxification of the food-derived carcinogen metabolite N-acetoxy-PhIP, and the effect of a polymorphism in hGSTA1 on colorectal cancer risk.
Mutation research 2001;482(1-2):3-10.
2001: George J Hammons; Yan Yan-Sanders; B Jin; EB Blann; Fred F Kadlubar; Beverly D Lyn-Cook
Specific site methylation in the 5'-flanking region of CYP1A2 interindividual differences in human livers.
Life sciences 2001;69(7):839-45.
2001: Wen Tan; G F Chen; De-yin Xing; C Y Song; Fred F Kadlubar; Dong-xin Lin
Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population.
International journal of cancer. Journal international du cancer 2001;95(2):96-101.
2001: Frederick W Wiese; P A Thompson; Fred F Kadlubar
Carcinogen substrate specificity of human COX-1 and COX-2.
Carcinogenesis 2001;22(1):5-10.
2000: YM Tang; B L Green; GF Chen; P A Thompson; Nicholas P Lang; A Shinde; Dong-xin Lin; W Tan; Beverly D Lyn-Cook; George J Hammons; Fred F Kadlubar
Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls.
Pharmacogenetics 2000;10(9):761-6.
2000: Susan Nowell; Christine B Ambrosone; S Ozawa; Stewart MacLeod; G Mrackova; Suzanne Williams; Jason Plaxco; Fred F Kadlubar; Nicholas P Lang
Relationship of phenol sulfotransferase activity (SULT1A1) genotype to sulfotransferase phenotype in platelet cytosol.
Pharmacogenetics 2000;10(9):789-97.
2000: David W Hein; Charlene A McQueen; Denis M Grant; Geoffrey H Goodfellow; Fred F Kadlubar; Wendell W Weber
Pharmacogenetics of the arylamine N-acetyltransferases: a symposium in honor of Wendell W. Weber.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(12):1425-32.
2000: Carol Sweeney; Gail Y McClure; Manal Y Fares; Angie Stone; Brian F Coles; PA Thompson; S Korourian; Laura F Hutchins; Fred F Kadlubar; Christine B Ambrosone
Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.
Cancer research 2000;60(20):5621-4.
2000: Stewart MacLeod; Susan Nowell; JP Massengill; Abdul-Rahman Jazieh; GY McClure; Jason Plaxco; Fred F Kadlubar; N P Lan
Cancer therapy and polymorphisms of cytochromes P450.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(9):883-7.
2000: Brian F Coles; M Yang; Nicholas P Lang; Fred F Kadlubar
Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide.
Cancer letters 2000;156(2):167-75.
2000: Roberta S King; Candee H Teitel; Fred F Kadlubar
In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.
Carcinogenesis 2000;21(7):1347-54.
2000: Peter P Fu; Linda S Von Tungeln; George J Hammons; G McMahon; G Wogan; T J Flammang; Fred F Kadlubar
Metabolic activation capacity of neonatal mice in relation to the neonatal mouse tumorigenicity bioassay.
Drug metabolism reviews 2000;32(2):241-66.
2000: Brian F Coles; K E Anderson; D R Doerge; M I Churchwell; Nicholas P Lang; Fred F Kadlubar
Quantitative analysis of interindividual variation of glutathione S-transferase expression in human pancreas and the ambiguity of correlating genotype with phenotype.
Cancer research 2000;60(3):573-9.
1999: F Peter Guengerich; R G Mundkowski; Markus Voehler; Fred F Kadlubar
Formation and reactions of N(7)-aminoguanosine and derivatives.
Chemical research in toxicology 1999;12(10):906-16.
1999: Roberta S King; Candee H Teitel; Joseph G Shaddock; Daniel A Casciano; Fred F Kadlubar
Detoxification of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivative.
Cancer letters 1999;143(2):167-71.
1999: Shioko Kimura; M Kawabe; Jerrold M Ward; Hideki Morishima; Fred F Kadlubar; George J Hammons; Pedro Fernandez-Salguero; Frank J Gonzalez
CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice.
Carcinogenesis 1999;20(9):1825-30.
1999: Beverly D Lyn-Cook; H L Stottman; Y Yan; EB Blann; Fred F Kadlubar; George J Hammons
The effects of phytoestrogens on human pancreatic tumor cells in vitro.
Cancer letters 1999;142(1):111-9.
1999: GF Chen; YM Tang; Bridgette Green; Dong-xin Lin; F P Guengerich; A K Daly; N E Caporaso; Fred F Kadlubar
Low frequency of CYP2A6 gene polymorphism as revealed by a one-step polymerase chain reaction method.
Pharmacogenetics 1999;9(3):327-32.
1999: Susan Nowell; J S Massengill; S Williams; Anna Radominska-Pandya; Thomas R Tephly; Z Cheng; C P Strassburg; Robert H Tukey; Stewart MacLeod; Nicholas P Lang; Fred F Kadlubar
Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.
Carcinogenesis 1999;20(6):1107-14.
1999: S Ozawa; Bernadette Schoket; L P McDaniel; Y M Tang; C B Ambrosone; Szilárd Kostic; I Vincze; Fred F Kadlubar
Analyses of bronchial bulky DNA adduct levels and CYP2C9, GSTP1 and NQO1 genotypes in a Hungarian study population with pulmonary diseases.
Carcinogenesis 1999;20(6):991-5.
1999: P A Thompson; F Seyedi; Nicholas P Lang; Stewart MacLeod; G N Wogan; K E Anderson; Y M Tang; Brian F Coles; Fred F Kadlubar
Comparison of DNA adduct levels associated with exogenous and endogenous exposures in human pancreas in relation to metabolic genotype.
Mutation research 1999;424(1-2):263-74.
1999: YM Tang; GF Chen; P A Thompson; Dong-xin Lin; Nicholas P Lang; Fred F Kadlubar
Development of an antipeptide antibody that binds to the C-terminal region of human CYP1B1.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(2):274-80.
1999: George J Hammons; Y Yan; NG Lopatina; B Jin; Carolyn Wise; EB Blann; Lionel A Poirier; Fred F Kadlubar; Beverly D Lyn-Cook
Increased expression of hepatic DNA methyltransferase in smokers.
Cell biology and toxicology 1999;15(6):389-94.
1999: Beverly D Lyn-Cook; T Rogers; Y Yan; EB Blann; Fred F Kadlubar; George J Hammons
Chemopreventive effects of tea extracts and various components on human pancreatic and prostate tumor cells in vitro.
Nutrition and cancer 1999;35(1):80-6.
1999: George J Hammons; J V Fletcher; K R Stepps; E A Smith; DA Balentine; ME Harbowy; Fred F Kadlubar
Effects of chemoprotective agents on the metabolic activation of the carcinogenic arylamines PhIP and 4-aminobiphenyl in human and rat liver microsomes.
Nutrition and cancer 1999;33(1):46-52.
1998: Dongxin Lin; Fred F Kadlubar; J Chen
[Direct detoxification of N-acetoxy-PhIP by tea polyphenols: a possible mechanism for chemoprevention against PhIP-DNA adduct formation in vivo].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 1998;32(5):265-9.
1998: H C Chou; S Ozawa; P P Fu; Nicholas P Lang; Fred F Kadlubar
Metabolic activation of methyl-hydroxylated derivatives of 7,12-dimethylbenz[a]anthracene by human liver dehydroepiandrosterone-steroid sulfotransferase.
Carcinogenesis 1998;19(6):1071-6.
1998: PA Thompson; Peter G Shields; Jo L Freudenheim; Angie Stone; John Edward Vena; James R Marshall; Saxon Graham; R Laughlin; T Nemoto; Fred F Kadlubar; Christine B Ambrosone
Genetic polymorphisms in catechol-O-methyltransferase, menopausal status, and breast cancer risk.
Cancer research 1998;58(10):2107-10.
1998: S Ozawa; Y M Tang; Y Yamazoe; R Kato; Nicholas P Lang; Fred F Kadlubar
Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines.
Chemico-biological interactions 1998;109(1-3):237-48.
1998: PA Thompson; Fred F Kadlubar; S M Vena; H L Hill; G H McClure; L P McDaniel; Christine B Ambrosone
Exfoliated ductal epithelial cells in human breast milk: a source of target tissue DNA for molecular epidemiologic studies of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(1):37-42.
1997: Sandra J Culp; Dean W Roberts; G Talaska; Nicholas P Lang; Peter P Fu; Jackson Lay; Candee H Teitel; J E Snawder; Linda S Von Tungeln; Fred F Kadlubar
Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation.
Mutation research 1997;378(1-2):97-112.
1997: Christine B Ambrosone; Fred F Kadlubar
Formation of a molecular epidemiology group?
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(8):651-3.
1997: Stewart MacLeod; Rashmi Sinha; Fred F Kadlubar; Nicholas P Lang
Polymorphisms of CYP1A1 and GSTM1 influence the in vivo function of CYP1A2.
Mutation research 1997;376(1-2):135-42.
1997: Wolfgang W Huber; L P McDaniel; Keith R Kaderlik; Candee H Teitel; Nicholas P Lang; Fred F Kadlubar
Chemoprotection against the formation of colon DNA adducts from the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat.
Mutation research 1997;376(1-2):115-22.
1997: Kristin E Anderson; George J Hammons; Fred F Kadlubar; John D Potter; Keith R Kaderlik; Kenneth F Ilett; R F Minchin; Candee H Teitel; H C Chou; M V Martin; F Peter Guengerich; G W Barone; Nicholas P Lang; L A Peterson
Metabolic activation of aromatic amines by human pancreas.
Carcinogenesis 1997;18(5):1085-92.
1996: H Raza; R S King; R. Burke Squires; F P Guengerich; D W Miller; J P Freeman; Nicholas P Lang; Fred F Kadlubar
Metabolism of 2-amino-alpha-carboline. A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(4):395-400.
1996: N J Butcher; Rodney F Minchin; Fred F Kadlubar; Kenneth F Ilett
Uptake of the food-derived heterocyclic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and its N-hydroxy metabolite into rat pancreatic acini and hepatocytes in vitro.
Carcinogenesis 1996;17(4):889-92.
1996: Alaa F Badawi; S J Stern; Nicholas P Lang; Fred F Kadlubar
Cytochrome P-450 and acetyltransferase expression as biomarkers of carcinogen-DNA adduct levels and human cancer susceptibility.
Progress in clinical and biological research 1996;395():109-40.
1996: Y C Ni; T Y Wong; R V Lloyd; Thomas Heinze; S Shelton; D Casciano; Fred F Kadlubar; Peter P Fu
Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(1):81-90.
1995: Fred F Kadlubar; A F Badawi
Genetic susceptibility and carcinogen-DNA adduct formation in human urinary bladder carcinogenesis.
Toxicology letters 1995;82-83():627-32.
1995: Y C Ni; Fred F Kadlubar; Peter P Fu
Formation of malondialdehyde-modified 2'-deoxyguanosinyl adduct from metabolism of chloral hydrate by mouse liver microsomes.
Biochemical and biophysical research communications 1995;216(3):1110-7.
1995: A F Badawi; A Hirvonen; Douglas A Bell; Nicholas P Lang; Fred F Kadlubar
Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder.
Cancer research 1995;55(22):5230-7.
1995: Douglas A Bell; A F Badawi; Nicholas P Lang; K F Ilett; Fred F Kadlubar; A Hirvonen
Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue.
Cancer research 1995;55(22):5226-9.
1995: D X Lin; Nicholas P Lang; Fred F Kadlubar
Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(4):518-24.
1995: H C Chou; Nicholas P Lang; Fred F Kadlubar
Metabolic activation of the N-hydroxy derivative of the carcinogen 4-aminobiphenyl by human tissue sulfotransferases.
Carcinogenesis 1995;16(2):413-7.
1995: Fred F Kadlubar; R K Kaderlik; G J Mulder; D Lin; M A Butler; Candee H Teitel; Rodney F Minchin; Kenneth F Ilett; Marlin Friesen; H Bartsch
Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis.
Princess Takamatsu symposia 1995;23():207-13.
1995: F Peter Guengerich; W G Humphreys; C H Yun; G J Hammons; Fred F Kadlubar; Y Seto; O Okazaki; M V Martin
Mechanisms of cytochrome P450 1A2-mediated formation of N-hydroxy arylamines and heterocyclic amines and their reaction with guanyl residues.
Princess Takamatsu symposia 1995;23():78-84.
1995: K R Kaderlik; Fred F Kadlubar
Metabolic polymorphisms and carcinogen-DNA adduct formation in human populations.
Pharmacogenetics 1995;5 Spec No():S108-17.
1994: Nicholas P Lang; M A Butler; J Massengill; M Lawson; R C Stotts; M Hauer-Jensen; Fred F Kadlubar
Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(8):675-82.
1994: Y C Ni; T Y Wong; Fred F Kadlubar; Peter P Fu
Hepatic metabolism of chloral hydrate to free radical(s) and induction of lipid peroxidation.
Biochemical and biophysical research communications 1994;204(2):937-43.
1994: D Lin; Jackson Lay; Matthew Bryant; C Malaveille; Marlin Friesen; H Bartsch; Nicholas P Lang; Fred F Kadlubar
Analysis of 4-aminobiphenyl-DNA adducts in human urinary bladder and lung by alkaline hydrolysis and negative ion gas chromatography-mass spectrometry.
Environmental health perspectives 1994;102 Suppl 6():11-6.
1994: D Lin; D J Meyer; B Ketterer; Nicholas P Lang; Fred F Kadlubar
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
Cancer research 1994;54(18):4920-6.
1994: M Degawa; Scott J Stern; M V Martin; F P Guengerich; P P Fu; Kenneth F Ilett; R K Kaderlik; Fred F Kadlubar
Metabolic activation and carcinogen-DNA adduct detection in human larynx.
Cancer research 1994;54(18):4915-9.
1994: K R Kaderlik; G J Mulder; J G Shaddock; D A Casciano; Candee H Teitel; Fred F Kadlubar
Effect of glutathione depletion and inhibition of glucuronidation and sulfation on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism, PhIP-DNA adduct formation and unscheduled DNA synthesis in primary rat hepatocytes.
Carcinogenesis 1994;15(8):1711-6.
1994: K R Kaderlik; Rodney F Minchin; G J Mulder; Kenneth F Ilett; M Daugaard-Jenson; Candee H Teitel; Fred F Kadlubar
Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues.
Carcinogenesis 1994;15(8):1703-9.
1994: K R Kaderlik; G J Mulder; Robert J Turesky; Nicholas P Lang; Candee H Teitel; M. Paul Chiarelli; Fred F Kadlubar
Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.
Carcinogenesis 1994;15(8):1695-701.
1994: Kenneth F Ilett; D M Ingram; D S Carpenter; Candee H Teitel; Nicholas P Lang; Fred F Kadlubar; Rodney F Minchin
Expression of monomorphic and polymorphic N-acetyltransferases in human colon.
Biochemical pharmacology 1994;47(5):914-7.
1994: R W West; W G Sheldon; David W Gaylor; R R Allen; Fred F Kadlubar
Study of sodium saccharin co-carcinogenicity in the rat.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1994;32(3):207-13.
1994: Peter P Fu; K L Dooley; Linda S Von Tungeln; Thomas J Bucci; Ronald W Hart; Fred F Kadlubar
Caloric restriction profoundly inhibits liver tumor formation after initiation by 6-nitrochrysene in male mice.
Carcinogenesis 1994;15(2):159-61.
1994: Fred F Kadlubar
Biochemical individuality and its implications for drug and carcinogen metabolism: recent insights from acetyltransferase and cytochrome P4501A2 phenotyping and genotyping in humans.
Drug metabolism reviews 1994;26(1-2):37-46.
1994: Fred F Kadlubar
DNA adducts of carcinogenic aromatic amines.
IARC scientific publications 1994;(125):199-216.
1993: Rodney F Minchin; Fred F Kadlubar; Kenneth F Ilett
Role of acetylation in colorectal cancer.
Mutation research 1993;290(1):35-42.
1993: D Segerbäck; K R Kaderlik; Glenn Talaska; K L Dooley; Fred F Kadlubar
32P-postlabelling analysis of DNA adducts of 4,4'-methylenebis(2-chloroaniline) in target and nontarget tissues in the dog and their implications for human risk assessment.
Carcinogenesis 1993;14(10):2143-7.
1993: Kenneth F Ilett; W M Castleden; Yvonne K Vandongen; Michael C Stacey; M A Butler; Fred F Kadlubar
Acetylation phenotype and cytochrome P450IA2 phenotype are unlikely to be associated with peripheral arterial disease.
Clinical pharmacology and therapeutics 1993;54(3):317-22.
1993: Douglas A Bell; Jack A Taylor; M A Butler; E A Stephens; J Wiest; L H Brubaker; Fred F Kadlubar; George W Lucier
Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans.
Carcinogenesis 1993;14(8):1689-92.
1992: R K Kaderlik; D X Lin; N P Lang; Fred F Kadlubar
Advantages and limitations of laboratory methods for measurement of carcinogen-DNA adducts for epidemiological studies.
Toxicology letters 1992;64-65 Spec No():469-75.
1992: Fred F Kadlubar
Detection of human DNA-carcinogen adducts.
Nature 1992;360(6400):189.
1992: F Peter Guengerich; Tsutomu Shimada; Kevin D Raney; C H Yun; D J Meyer; B Ketterer; Thomas Harris; John Groopman; Fred F Kadlubar
Elucidation of catalytic specificities of human cytochrome P450 and glutathione S-transferase enzymes and relevance to molecular epidemiology.
Environmental health perspectives 1992;98():75-80.
1992: Fred F Kadlubar; M A Butler; K R Kaderlik; H C Chou; Nicholas P Lang
Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis.
Environmental health perspectives 1992;98():69-74.
1992: David W Gaylor; Fred F Kadlubar; Frederick A Beland
Application of biomarkers to risk assessment.
Environmental health perspectives 1992;98():139-41.
1992: W G Humphreys; Fred F Kadlubar; F Peter Guengerich
Mechanism of C8 alkylation of guanine residues by activated arylamines: evidence for initial adduct formation at the N7 position.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8278-82.
1992: D Lin; K R Kaderlik; Robert J Turesky; D W Miller; Jackson Lay; Fred F Kadlubar
Identification of N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA.
Chemical research in toxicology 1992;5(5):691-7.
1992: D Segerbäck; Fred F Kadlubar
Characterization of 4,4'-methylenebis(2-chloroaniline)--DNA adducts formed in vivo and in vitro.
Carcinogenesis 1992;13(9):1587-92.
1992: S Yu; D Herreno-Saenz; D W Miller; Fred F Kadlubar; Peter P Fu
Mutagenicity of nitro-polycyclic aromatic hydrocarbons with the nitro substituent situated at the longest molecular axis.
Mutation research 1992;283(1):45-52.
1992: Rodney F Minchin; P T Reeves; Candee H Teitel; Michael E McManus; Behnaz Mojarrabi; Kenneth F Ilett; Fred F Kadlubar
N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells.
Biochemical and biophysical research communications 1992;185(3):839-44.
1992: M A Butler; Nicholas P Lang; J F Young; N E Caporaso; P Vineis; R B Hayes; Candee H Teitel; J P Massengill; M F Lawsen; Fred F Kadlubar
Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.
Pharmacogenetics 1992;2(3):116-27.
1992: Rodney F Minchin; Kenneth F Ilett; Candee H Teitel; P T Reeves; Fred F Kadlubar
Direct O-acetylation of N-hydroxy arylamines by acetylsalicylic acid to form carcinogen-DNA adducts.
Carcinogenesis 1992;13(4):663-7.
1992: K L Dooley; Linda S Von Tungeln; Thomas J Bucci; Peter P Fu; Fred F Kadlubar
Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse.
Cancer letters 1992;62(3):205-9.
1991: Robert J Turesky; Nicholas P Lang; M A Butler; Candee H Teitel; Fred F Kadlubar
Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
Carcinogenesis 1991;12(10):1839-45.
1991: S Y Yu; Robert H Heflich; Linda S Von Tungeln; K el-Bayoumy; Fred F Kadlubar; Peter P Fu
Comparative direct-acting mutagenicity of 1- and 2-nitropyrene: evidence for 2-nitropyrene mutagenesis by both guanine and adenine adducts.
Mutation research 1991;250(1-2):145-52.
1991: Fred F Kadlubar; K L Dooley; Candee H Teitel; D W Roberts; R W Benson; M A Butler; J R Bailey; J F Young; P W Skipper; S R Tannenbaum
Frequency of urination and its effects on metabolism, pharmacokinetics, blood hemoglobin adduct formation, and liver and urinary bladder DNA adduct levels in beagle dogs given the carcinogen 4-aminobiphenyl.
Cancer research 1991;51(16):4371-7.
1991: Kenneth F Ilett; P T Reeves; Rodney F Minchin; B F Kinnear; H F Watson; Fred F Kadlubar
Distribution of acetyltransferase activities in the intestines of rapid and slow acetylator rabbits.
Carcinogenesis 1991;12(8):1465-9.
1991: Glenn Talaska; A Z al-Juburi; Fred F Kadlubar
Smoking related carcinogen-DNA adducts in biopsy samples of human urinary bladder: identification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl as a major adduct.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5350-4.
1991: D W Roberts; R W Benson; Jack A Hinson; Fred F Kadlubar
Critical considerations in the immunochemical detection and quantitation of antigenic biomarkers.
Biomedical and environmental sciences : BES 1991;4(1-2):113-29.
1991: R W West; Fred F Kadlubar
The effects of sodium saccharin with and without N-methyl-N-nitrosourea co-treatment on anchorage-independent growth of human diploid fibroblasts.
Toxicology in vitro : an international journal published in association with BIBRA 1991;5(3):257-62.
1990: B P Cho; Fred F Kadlubar; S J Culp; F E Evans
15N nuclear magnetic resonance studies on the tautomerism of 8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanosine, and other C8-substituted guanine nucleosides.
Chemical research in toxicology 1990;3(5):445-52.
1990: J C Wohlleb; C F Hunter; B Blass; Fred F Kadlubar; D Z Chu; N P Lang
Aromatic amine acetyltransferase as a marker for colorectal cancer: environmental and demographic associations.
International journal of cancer. Journal international du cancer 1990;46(1):22-30.
1990: Fred F Kadlubar; Peter P Fu; H Jung; A U Shaikh; Frederick A Beland
The metabolic N-oxidation of carcinogenic arylamines in relation to nitrogen charge density and oxidation potential.
Environmental health perspectives 1990;87():233-6.
1990: Glenn Talaska; K L Dooley; Fred F Kadlubar
Detection and characterization of carcinogen-DNA adducts in exfoliated urothelial cells from 4-aminobiphenyl-treated dogs by 32P-postlabelling and subsequent thin-layer and high-pressure liquid chromatography.
Carcinogenesis 1990;11(4):639-46.
1990: Fred F Kadlubar; Glenn Talaska; M A Butler; Candee H Teitel; J P Massengill; Nicholas P Lang
Determination of carcinogenic arylamine N-oxidation phenotype in humans by analysis of caffeine urinary metabolites.
Progress in clinical and biological research 1990;340B():107-14.
1990: Fred F Kadlubar
Carcinogenic aromatic amine metabolism and DNA adduct detection in humans.
Princess Takamatsu symposia 1990;21():329-38.
1989: S J Culp; B P Cho; Fred F Kadlubar; F E Evans
Structural and conformational analyses of 8-hydroxy-2'-deoxyguanosine.
Chemical research in toxicology 1989;2(6):416-22.
1989: G J Hammons; William L Alworth; N E Hopkins; F Peter Guengerich; Fred F Kadlubar
2-ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P-450 catalyzed N-oxidation of 2-naphthylamine.
Chemical research in toxicology 1989;2(6):367-74.
1989: M A Butler; M Iwasaki; F P Guengerich; Fred F Kadlubar
Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):7696-700.
1989: K B Delclos; Karam El-Bayoumy; Daniel A Casciano; R P Walker; Fred F Kadlubar; Stephen S Hecht; N Shivapurkar; S Mandal; Gary D Stoner
Metabolic activation of 6-nitrochrysene in explants of human bronchus and in isolated rat hepatocytes.
Cancer research 1989;49(11):2909-13.
1989: T J Flammang; Y Yamazoe; R W Benson; D W Roberts; D W Potter; D Z Chu; N P Lang; Fred F Kadlubar
Arachidonic acid-dependent peroxidative activation of carcinogenic arylamines by extrahepatic human tissue microsomes.
Cancer research 1989;49(8):1977-82.
1989: C B Frederick; K L Dooley; R L Kodell; W G Sheldon; Fred F Kadlubar
The effect of lifetime sodium saccharin dosing on mice initiated with the carcinogen 2-acetylaminofluorene.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1989;12(2):346-57.
1989: M A Butler; F P Guengerich; Fred F Kadlubar
Metabolic oxidation of the carcinogens 4-aminobiphenyl and 4,4'-methylene-bis(2-chloroaniline) by human hepatic microsomes and by purified rat hepatic cytochrome P-450 monooxygenases.
Cancer research 1989;49(1):25-31.
1989: R S Krauss; Julie Angerman-Stewart; Thomas E Eling; K L Dooley; Fred F Kadlubar
The formation of 2-aminofluorene-DNA adducts in vivo: evidence for peroxidase-mediated activation.
Journal of biochemical toxicology 1989;4(2):111-7.
1988: D W Gaylor; Fred F Kadlubar; R Webster West
Estimates of the risk of bladder tumor promotion by saccharin in rats.
Regulatory toxicology and pharmacology : RTP 1988;8(4):467-70.
1988: D W Roberts; R W Benson; John Groopman; T J Flammang; W A Nagle; A J Moss; Fred F Kadlubar
Immunochemical quantitation of DNA adducts derived from the human bladder carcinogen 4-aminobiphenyl.
Cancer research 1988;48(22):6336-42.
1988: K B Delclos; Karam El-Bayoumy; Stephen S Hecht; R P Walker; Fred F Kadlubar
Metabolism of the carcinogen [3H]6-nitrochrysene in the preweanling mouse: identification of 6-aminochrysene-1,2-dihydrodiol as the probable proximate carcinogenic metabolite.
Carcinogenesis 1988;9(10):1875-84.
1988: Y Yamazoe; T V Zenser; D W Miller; Fred F Kadlubar
Mechanism of formation and structural characterization of DNA adducts derived from peroxidative activation of benzidine.
Carcinogenesis 1988;9(9):1635-41.
1988: K L Dooley; J F Stavenuiter; J G Westra; Fred F Kadlubar
Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse.
Cancer letters 1988;41(1):99-103.
1988: Fred F Kadlubar; Glenn Talaska; N P Lang; R W Benson; D W Roberts
Assessment of exposure and susceptibility to aromatic amine carcinogens.
IARC scientific publications 1988;(89):166-74.
1987: T J Flammang; Y Yamazoe; F Peter Guengerich; Fred F Kadlubar
The S-acetyl coenzyme A-dependent metabolic activation of the carcinogen N-hydroxy-2-aminofluorene by human liver cytosol and its relationship to the aromatic amine N-acetyltransferase phenotype.
Carcinogenesis 1987;8(12):1967-70.
1987: K B Delclos; R P Walker; K L Dooley; Peter P Fu; Fred F Kadlubar
Carcinogen-DNA adduct formation in the lungs and livers of preweanling CD-1 male mice following administration of [3H]-6-nitrochrysene, [3H]-6-aminochrysene, and [3H]-1,6-dinitropyrene.
Cancer research 1987;47(23):6272-7.
1987: K B Delclos; D W Miller; Jackson Lay; Daniel A Casciano; R P Walker; Peter P Fu; Fred F Kadlubar
Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vitro reaction of N-hydroxy-6-aminochrysene with DNA and the formation of these adducts in isolated rat hepatocytes treated with 6-nitrochrysene and 6-aminochrysene.
Carcinogenesis 1987;8(11):1703-9.
1987: Y C Ni; Robert H Heflich; Fred F Kadlubar; Peter P Fu
Mutagenicity of nitrofurans in Salmonella typhimurium TA98, TA98NR and TA98/1,8-DNP6.
Mutation research 1987;192(1):15-22.
1986: R W West; W G Sheldon; David W Gaylor; M G Haskin; R R Delongchamp; Fred F Kadlubar
The effects of saccharin on the development of neoplastic lesions initiated with N-methyl-N-nitrosourea in the rat urothelium.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1986;7(4):585-600.
1986: N P Lang; D Z Chu; C F Hunter; D C Kendall; T J Flammang; Fred F Kadlubar
Role of aromatic amine acetyltransferase in human colorectal cancer.
Archives of surgery (Chicago, Ill. : 1960) 1986;121(11):1259-61.
1980: Fred F Kadlubar; K M Straub; L E Unruh; Frederick A Beland; F E Evans
In vitro reaction of the carcinogen, N-hydroxy-2-naphthylamine, with DNA at the C-8 and N2 atoms of guanine and at the N6 atom of adenine.
Carcinogenesis 1980;1(2):139-50.