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Jaspal Kaeda

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Christian Oberender; Bärbel Pawlaczyk-Peter; Renate Arnold; Peter Daniel; Bernd Dörken; Jaspal Kaeda; Philipp le Coutre
Sequencing of NUMB transcripts in chronic myeloid leukemia detects two single nucleotide polymorphisms.
Theo D Kim; Michaela Schwarz; Karl-Anton Kreuzer; Jaspal Kaeda; Kamran Movassaghi; Peggy Grille; Peter T Daniel; Bernd Dörken; Philipp le Coutre
Long-term follow-up of patients with Philadelphia chromosome-positive chronic myeloid leukemia after stem cell mobilization under imatinib.
David Marin; Dragana Milojkovic; Eduardo Olavarria; Jamshid Sorouri Khorashad; Hugues de Lavallade; Alistair G Reid; Letizia Foroni; K Rezvani; Marco Bua; Francesco Dazzi; Jiri Pavlu; Matthias Klammer; Jaspal Kaeda; John M Goldman; Jane F Apperley
European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor.

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2013: Christian Oberender; Bärbel Pawlaczyk-Peter; Renate Arnold; Peter Daniel; Bernd Dörken; Jaspal Kaeda; Philipp le Coutre
Sequencing of NUMB transcripts in chronic myeloid leukemia detects two single nucleotide polymorphisms.
Leukemia & lymphoma 2013;54(2):421-2.
2011: Theo D Kim; Michaela Schwarz; Karl-Anton Kreuzer; Jaspal Kaeda; Kamran Movassaghi; Peggy Grille; Peter T Daniel; Bernd Dörken; Philipp le Coutre
Long-term follow-up of patients with Philadelphia chromosome-positive chronic myeloid leukemia after stem cell mobilization under imatinib.
Leukemia & lymphoma 2011;52(3):517-20.
2008: David Marin; Dragana Milojkovic; Eduardo Olavarria; Jamshid Sorouri Khorashad; Hugues de Lavallade; Alistair G Reid; Letizia Foroni; K Rezvani; Marco Bua; Francesco Dazzi; Jiri Pavlu; Matthias Klammer; Jaspal Kaeda; John M Goldman; Jane F Apperley
European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor.
Blood 2008;112(12):4437-44.
2008: Jamshid Sorouri Khorashad; Hugues de Lavallade; Jane F Apperley; Dragana Milojkovic; Alistair G Reid; Marco Bua; Richard Szydlo; Eduardo Olavarria; Jaspal Kaeda; John M Goldman; David Marin
Finding of kinase domain mutations in patients with chronic phase chronic myeloid leukemia responding to imatinib may identify those at high risk of disease progression.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(29):4806-13.
2008: Hugues de Lavallade; Jane F Apperley; Jamshid Sorouri Khorashad; Dragana Milojkovic; Alistair G Reid; Marco Bua; Richard Szydlo; Eduardo Olavarria; Jaspal Kaeda; John M Goldman; David Marin
Imatinib for newly diagnosed patients with chronic myeloid leukemia: incidence of sustained responses in an intention-to-treat analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(20):3358-63.
2008: Jamshid Sorouri Khorashad; Dragana Milojkovic; Puja Mehta; Mona Anand; Sara Ghorashian; Alistair G Reid; Valeria De Melo; Anna Babb; Hugues de Lavallade; Eduardo Olavarria; David Marin; John M Goldman; Jane F Apperley; Jaspal Kaeda
In vivo kinetics of kinase domain mutations in CML patients treated with dasatinib after failing imatinib.
Blood 2008;111(4):2378-81.
2007: Hugues de Lavallade; Jamshid Sorouri Khorashad; Howard P Davis; Dragana Milojkovic; Jaspal Kaeda; John M Goldman; Jane F Apperley; David Marin
Interferon-alpha or homoharringtonine as salvage treatment for chronic myeloid leukemia patients who acquire the T315I BCR-ABL mutation.
Blood 2007;110(7):2779-80.
2007: Jiri Pavlu; Catharina Andreasson; Charles Chuah; Jaspal Kaeda; John M Goldman; Jane F Apperley; David Marin
Dual inhibition of ras and bcr-abl signalling pathways in chronic myeloid leukaemia: a phase I/II study in patients in complete haematological remission.
British journal of haematology 2007;137(5):423-8.
2007: M P Simula; Sarah Marktel; Claudio Fozza; Jaspal Kaeda; Richard Szydlo; Elisabet Nadal; Marco Bua; Amin Rahemtulla; Edward Kanfer; David Marin; Eduardo Olavarria; John M Goldman; Jane F Apperley; Francesco Dazzi
Response to donor lymphocyte infusions for chronic myeloid leukemia is dose-dependent: the importance of escalating the cell dose to maximize therapeutic efficacy.
Leukemia 2007;21(5):943-8.
2007: Elisabet Nadal; M Garin; Jaspal Kaeda; Jane Apperley; Robert Lechler; Francesco Dazzi
Increased frequencies of CD4(+)CD25(high) T(regs) correlate with disease relapse after allogeneic stem cell transplantation for chronic myeloid leukemia.
Leukemia 2007;21(3):472-9.
2006: Susan Branford; Nicholas C P Cross; Andreas Hochhaus; Jerald P Radich; Giuseppe Saglio; Jaspal Kaeda; J Goldman; Timothy Hughes
Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia.
Leukemia 2006;20(11):1925-30.
2006: Mona Anand; Jamshid Sorouri Khorashad; David Marin; Jane F Apperley; John M Goldman; Jaspal Kaeda
Varying response to escalating the dose of imatinib in patients with CML who "acquire" a BCR-ABL M244V mutant allele.
Blood 2006;108(8):2881-2.
2006: Timothy Hughes; Michael W N Deininger; Andreas Hochhaus; Susan Branford; Jerald P Radich; Jaspal Kaeda; Michele Baccarani; Jorge Cortes; Nicholas C P Cross; Brian J Druker; Jean Gabert; David Grimwade; Rüdiger Hehlmann; Suzanne Kamel-Reid; Jeffrey H Lipton; Janina Longtine; giovanni martinelli; Giuseppe Saglio; Simona Soverini; Wendy Stock; John M Goldman
Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results.
Blood 2006;108(1):28-37.
2006: Jaspal Kaeda; Derville O'Shea; Richard Szydlo; Eduardo Olavarria; Francesco Dazzi; David Marin; Susan Saunders; Jamshid Sorouri Khorashad; Nicholas C P Cross; John M Goldman; Jane F Apperley
Serial measurement of BCR-ABL transcripts in the peripheral blood after allogeneic stem cell transplantation for chronic myeloid leukemia: an attempt to define patients who may not require further therapy.
Blood 2006;107(10):4171-6.
2006: Jamshid Sorouri Khorashad; M Anand; David Marin; S Saunders; T Al-Jabary; A Iqbal; S Margerison; J V Melo; John M Goldman; Jane F Apperley; Jaspal Kaeda
The presence of a BCR-ABL mutant allele in CML does not always explain clinical resistance to imatinib.
Leukemia 2006;20(4):658-63.
2006: Roopinder Gillmore; Shao-An Xue; shao-an xue; Jaspal Kaeda; Dimitri Hadjiminas; Vourneen Healy; Roberto Dina; Suzanne C Parry; Ilaria Bellantuono; Yasmeen Ghani; R Charles Coombes; Jonathan Waxman; Hans J Stauss
Detection of Wilms' tumor antigen--specific CTL in tumor-draining lymph nodes of patients with early breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):34-42.
2005: Jane M E Withey; Stephen B Marley; Jaspal Kaeda; Amanda J Harvey; Mark R Crompton; Myrtle Y Gordon
Targeting primary human leukaemia cells with RNA interference: Bcr-Abl targeting inhibits myeloid progenitor self-renewal in chronic myeloid leukaemia cells.
British journal of haematology 2005;129(3):377-80.
2005: David Marin; Jaspal Kaeda; Catharina Andreasson; Sue M Saunders; Marco Bua; Eduardo Olavarria; John M Goldman; Jane F Apperley
Phase I/II trial of adding semisynthetic homoharringtonine in chronic myeloid leukemia patients who have achieved partial or complete cytogenetic response on imatinib.
Cancer 2005;103(9):1850-5.
2005: David Marin; Jaspal Kaeda; Richard Szydlo; S Saunders; A Fleming; J Howard; Catharina Andreasson; Marco Bua; Eduardo Olavarria; Amin Rahemtulla; Francesco Dazzi; Edward Kanfer; John M Goldman; Jane F Apperley
Monitoring patients in complete cytogenetic remission after treatment of CML in chronic phase with imatinib: patterns of residual leukaemia and prognostic factors for cytogenetic relapse.
Leukemia 2005;19(4):507-12.
2005: Simon D Wagner; Jaspal Kaeda
BCL-6: rearrangement and mutation in lymphoma.
Methods in molecular medicine 2005;115():251-70.
2004: Zi-xing Chen; Jaspal Kaeda; Sue Saunders; John M Goldman
Expression patterns of WT-1 and Bcr-Abl measured by TaqMan quantitative real-time RT-PCR during follow-up of leukemia patients with the Ph chromosome.
Chinese medical journal 2004;117(7):968-71.
2004: S Avery; Elisabet Nadal; David Marin; Eduardo Olavarria; Jaspal Kaeda; Tom Vulliamy; F Brito Babapulle; John M Goldman; Jane F Apperley
Lymphoid transformation in a CML patient in complete cytogenetic remission following treatment with imatinib.
Leukemia research 2004;28 Suppl 1():S75-7.
2003: Timothy P Hughes; Jaspal Kaeda; Susan Branford; Zbigniew Rudzki; Andreas Hochhaus; Martee Hensley; Insa Gathmann; Ann E Bolton; Iris C van Hoomissen; John M Goldman; Jerald P Radich
Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia.
The New England journal of medicine 2003;349(15):1423-32.
2003: Myrtle Y Gordon; Stephen B Marley; Jane F Apperley; David Marin; Jaspal Kaeda; Richard Szydlo; John M Goldman
Clinical heterogeneity in chronic myeloid leukaemia reflecting biological diversity in normal persons.
British journal of haematology 2003;122(3):424-9.
2003: Feng Lin; Mark Drummond; Stephen O'Brien; Francisco Cervantes; John Goldman; Jaspal Kaeda
Molecular monitoring in chronic myeloid leukemia patients who achieve complete cytogenetic remission on imatinib.
Blood 2003;102(3):1143.
2003: Jaspal Kaeda; Jane Apperley; Junia Melo; Nicolas Cross; John Goldman
Monitoring CML after nonmyeloablative transplantations: how negative is negative?
Blood 2003;101(12):5084; author reply 5084-5.
2003: Liquan Gao; Shao-An Xue; Robert P Hasserjian; Finbarr Cotter; Jaspal Kaeda; John M Goldman; Francesco Dazzi; Hans J Stauss
Human cytotoxic T lymphocytes specific for Wilms' tumor antigen-1 inhibit engraftment of leukemia-initiating stem cells in non-obese diabetic-severe combined immunodeficient recipients.
Transplantation 2003;75(9):1429-36.
2002: Alicja M Gruszka-Westwood; Shayne Atkinson; Brenda Summersgill; Janet Shipley; Manal O Elnenaei; PARESH JAIN; Rifat A Hamoudi; Jaspal Kaeda; Andrew C Wotherspoon; Estella Matutes; Daniel Catovsky
Unusual case of leukemic mantle cell lymphoma with amplified CCND1/IGH fusion gene.
Genes, chromosomes & cancer 2002;33(2):206-12.
2002: Jaspal Kaeda; Andrew Chase; John M Goldman
Cytogenetic and molecular monitoring of residual disease in chronic myeloid leukaemia.
Acta haematologica 2002;107(2):64-75.
2001: Tariq I Mughal; Agnes S M Yong; Richard Szydlo; Francesco Dazzi; Eduardo Olavarria; F van Rhee; Jaspal Kaeda; Nicholas C P Cross; Charles Craddock; Edward Kanfer; Jane Apperley; John M Goldman
Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse.
British journal of haematology 2001;115(3):569-74.
2001: Kate Cwynarski; R Goulding; CF Pocock; Francesco Dazzi; Charles Craddock; Jaspal Kaeda; Eduardo Olavarria; Edward Kanfer; Jane Apperley; M Lawler; John M Goldman
Immune haemolytic anaemia following T cell-depleted allogeneic bone marrow transplantation for chronic myeloid leukaemia: association with leukaemic relapse and treatment with donor lymphocyte infusions.
Bone marrow transplantation 2001;28(6):581-6.
2001: Persis J Amrolia; Tom Vulliamy; G Vassiliou; Sarah Lawson; J Bryon; Jaspal Kaeda; Inderjeet Dokal; R Johnston; Paul Veys; Philip J Darbyshire; Irene A G Roberts
Analysis of chimaerism in thalassaemic children undergoing stem cell transplantation.
British journal of haematology 2001;114(1):219-25.
2001: Eduardo Olavarria; Edward Kanfer; Richard Szydlo; Jaspal Kaeda; K Rezvani; Kate Cwynarski; CF Pocock; Francesco Dazzi; Charles Craddock; Jane F Apperley; Nicholas C P Cross; John M Goldman
Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia.
Blood 2001;97(6):1560-5.
2000: Francesco Dazzi; Richard Szydlo; Nicholas C P Cross; Charles Craddock; Jaspal Kaeda; Edward Kanfer; Kate Cwynarski; Eduardo Olavarria; Agnes S M Yong; Jane F Apperley; John M Goldman
Durability of responses following donor lymphocyte infusions for patients who relapse after allogeneic stem cell transplantation for chronic myeloid leukemia.
Blood 2000;96(8):2712-6.
2000: Andrew Chase; S Parker; Jaspal Kaeda; R Sivalingam; N C Cross; J M Goldman
Absence of host-derived cells in the blood of patients in remission after allografting for chronic myeloid leukemia.
Blood 2000;96(2):777-8.
2000: Shashikant Kulkarni; C Heath; S Parker; Andrew Chase; S Iqbal; CF Pocock; Jaspal Kaeda; Kate Cwynarski; John M Goldman; Nicholas C P Cross
Fusion of H4/D10S170 to the platelet-derived growth factor receptor beta in BCR-ABL-negative myeloproliferative disorders with a t(5;10)(q33;q21).
Cancer research 2000;60(13):3592-8.
2000: Francesco Dazzi; Richard Szydlo; Charles Craddock; Nicholas C P Cross; Jaspal Kaeda; Andrew Chase; Eduardo Olavarria; F van Rhee; Edward Kanfer; Jane F Apperley; John M Goldman
Comparison of single-dose and escalating-dose regimens of donor lymphocyte infusion for relapse after allografting for chronic myeloid leukemia.
Blood 2000;95(1):67-71.
1999: R Kotea; Jaspal Kaeda; S L Yan; N Sem Fa; S Beesoon; S Jankee; Rajendranath Ramasawmy; Tom Vulliamy; R W Bradnock; J Bautista; L Luzzatto; Rajagopal Krishnamoorthy; Philip J Mason
Three major G6PD-deficient polymorphic variants identified among the Mauritian population.
British journal of haematology 1999;104(4):849-54.
1998: Tom Vulliamy; Jaspal Kaeda; D Ait-Chafa; R Mangerini; David Roper; J Barbot; Atul B Mehta; M Athanassiou-Metaxa; L Luzzatto; Philip J Mason
Clinical and haematological consequences of recurrent G6PD mutations and a single new mutation causing chronic nonspherocytic haemolytic anaemia.
British journal of haematology 1998;101(4):670-5.
1997: A Spencer; Tom Vulliamy; Jaspal Kaeda; J M Goldman; J V Melo
Clonal instability preceding lymphoid blastic transformation of chronic myeloid leukemia.
Leukemia 1997;11(2):195-201.
1996: Shahina Daar; Tom Vulliamy; Jaspal Kaeda; Philip J Mason; Lucio Luzzatto
Molecular characterization of G6PD deficiency in Oman.
Human heredity 1996;46(3):172-6.
1996: Riad Bayoumi; MS Nur-E-Kamal; M Tadayyon; K K Mohamed; B H Mahboob; MM Qureshi; M S Lakhani; M O Awaad; Jaspal Kaeda; Tom Vulliamy; Lucio Luzzatto
Molecular characterization of erythrocyte glucose-6-phosphate dehydrogenase deficiency in Al-Ain District, United Arab Emirates.
Human heredity 1996;46(3):136-41.
1996: K Konstantopoulos; Tom Vulliamy; D Swirsky; J D Reeves; Jaspal Kaeda; Lucio Luzzatto
DNA haplotypes in Africans and West Indians with sickle cell anaemia or SC disease.
Gene geography : a computerized bulletin on human gene frequencies 1996;10(1):19-24.
1995: Jaspal Kaeda; G P Chhotray; M R Ranjit; José M Bautista; P Hemachandra Reddy; D Stevens; J M Naidu; R P Britt; Tom Vulliamy; Lucio Luzzatto
A new glucose-6-phosphate dehydrogenase variant, G6PD Orissa (44 Ala-->Gly), is the major polymorphic variant in tribal populations in India.
American journal of human genetics 1995;57(6):1335-41.
1995: P Srivastava; Jaspal Kaeda; D Roper; Tom Vulliamy; M Buckley; Lucio Luzzatto
Severe hemolytic anemia associated with the homozygous state for an unstable hemoglobin variant (Hb Bushwick).
Blood 1995;86(5):1977-82.
1995: Philip J Mason; M F Sonati; D MacDonald; C Lanza; D Busutil; M Town; C M Corcoran; Jaspal Kaeda; D J Stevens; S al-Ismail
New glucose-6-phosphate dehydrogenase mutations associated with chronic anemia.
Blood 1995;85(5):1377-80.
1994: Jaspal Kaeda; K Prasad; R J Howard; A Mehta; Tom Vulliamy; Lucio Luzzatto
Management of pregnancy when maternal blood has a very high level of fetal haemoglobin.
British journal of haematology 1994;88(2):432-4.