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Ryoichiro Kageyama
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25
Ohtsuka, Toshiyuki
22
Nakanishi, Shigetada
17
Bessho, Yasumasa
11
Ishibashi, M
10
Hatakeyama, Jun
10
Tomita, K
9
Imayoshi, Itaru
8
Hirata, Hiromi
7
Inoue, Tomoyuki
7
Masamizu, Yoshito
6
Guillemot, François
5
Hojo, Masato
5
Hashimoto, Nobuo
5
Kobayashi, Taeko
5
Takahashi, Masayo
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All Publications
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2009: Murata Junko; Ohtsuka Toshiyuki; Tokunaga Akinori; Nishiike Suetaka; Inohara Hidenori; Okano Hideyuki; Kageyama Ryoichiro
Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1.
Journal of neuroscience research 2009;87(16):3521-34.
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2009: Arai Midori A; Masada Ayako; Ohtsuka Toshiyuki; Kageyama Ryoichiro; Ishibashi Masami
The first Hes1 dimer inhibitors from natural products.
Bioorganic & medicinal chemistry letters 2009;19(19):5778-81.
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2009: Nagahara Hiroki; Ma Yue; Takenaka Yoshiko; Kageyama Ryoichiro; Yoshikawa Kenichi
Spatiotemporal pattern in somitogenesis: a non-Turing scenario with wave propagation.
Physical review. E, Statistical, nonlinear, and soft matter physics 2009;80(2 Pt 1):021906.
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2009: Kobayashi Taeko; Mizuno Hiroaki; Imayoshi Itaru; Furusawa Chikara; Shirahige Katsuhiko; Kageyama Ryoichiro
The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells.
Genes & development 2009;23(16):1870-5.
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2009: González Aitor; Kageyama Ryoichiro
Hopf bifurcation in the presomitic mesoderm during the mouse segmentation.
Journal of theoretical biology 2009;259(1):176-89.
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2009: Kageyama Ryoichiro; Niwa Yasutaka; Shimojo Hiromi
Rhythmic gene expression in somite formation and neural development.
Molecules and cells 2009;27(5):497-502.
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2009: Imayoshi Itaru; Sakamoto Masayuki; Ohtsuka Toshiyuki; Kageyama Ryoichiro
Continuous neurogenesis in the adult brain.
Development, growth & differentiation 2009;51(3):379-86.
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2009: Wall Dana S; Mears Alan J; McNeill Brian; Mazerolle Chantal; Thurig Sherry; Wang Yaping; Kageyama Ryoichiro; Wallace Valerie A
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity.
The Journal of cell biology 2009;184(1):101-12.
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2009: Kobayashi Taeko; Kageyama Ryoichiro
Dynamic advances in NF-kappaB signaling analysis.
Science signaling 2009;2(81):pe47.
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2008: Hu Xiaoyu; Chung Allen Y; Wu Indira; Foldi Julia; Chen Janice; Ji Jong Dae; Tateya Tomoko; Kang Young Jun; Han Jiahuai; Gessler Manfred; Kageyama Ryoichiro; Ivashkiv Lionel B
Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways.
Immunity 2008;29(5):691-703.
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2008: Kageyama Ryoichiro; Ohtsuka Toshiyuki; Shimojo Hiromi; Imayoshi Itaru
Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition.
Nature neuroscience 2008;11(11):1247-51.
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2008: Imayoshi Itaru; Sakamoto Masayuki; Ohtsuka Toshiyuki; Takao Keizo; Miyakawa Tsuyoshi; Yamaguchi Masahiro; Mori Kensaku; Ikeda Toshio; Itohara Shigeyoshi; Kageyama Ryoichiro
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain.
Nature neuroscience 2008;11(10):1153-61.
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2008: Imayoshi Itaru; Shimogori Tomomi; Ohtsuka Toshiyuki; Kageyama Ryoichiro
Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline.
Development (Cambridge, England) 2008;135(15):2531-41.
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2008: Ishii Akiko; Kobayashi Taeko; Kageyama Ryoichiro
Requirement of multiple lysine residues for the transcriptional activity and the instability of Hes7.
Biochemical and biophysical research communications 2008;372(1):142-6.
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2008: Kageyama Ryoichiro; Ohtsuka Toshiyuki; Kobayashi Taeko
Roles of Hes genes in neural development.
Development, growth & differentiation 2008;50 Suppl 1():S97-103.
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2008: Nakamura Takahiro; Ohtsuka Toshiyuki; Sekiyama Eiichi; Cooper Leanne J; Kokubu Hiroshi; Fullwood Nigel J; Barrandon Yann; Kageyama Ryoichiro; Kinoshita Shigeru
Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells.
Stem cells (Dayton, Ohio) 2008;26(5):1265-74.
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2008: Nakayama Kei; Satoh Takayuki; Igari Aiko; Kageyama Ryoichiro; Nishida Eisuke
FGF induces oscillations of Hes1 expression and Ras/ERK activation.
Current biology : CB 2008;18(8):R332-4.
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2008: Kageyama Ryoichiro
[Transcription factor network that regulates neural development]
Brain and nerve = Shinkei kenkyu no shinpo 2008;60(4):329-33.
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2008: Shimojo Hiromi; Ohtsuka Toshiyuki; Kageyama Ryoichiro
Oscillations in notch signaling regulate maintenance of neural progenitors.
Neuron 2008;58(1):52-64.
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2008: Ohsawa Ryosuke; Kageyama Ryoichiro
Regulation of retinal cell fate specification by multiple transcription factors.
Brain research 2008;1192():90-8.
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2008: Kokubu Hiroshi; Ohtsuka Toshiyuki; Kageyama Ryoichiro
Mash1 is required for neuroendocrine cell development in the glandular stomach.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(1):41-51.
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2008: Kinameri Emi; Inoue Takashi; Aruga Jun; Imayoshi Itaru; Kageyama Ryoichiro; Shimogori Tomomi; Moore Adrian W
Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.
PloS one 2008;3(12):e3859.
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2007: Ikeda Keiko; Ookawara Shigeo; Sato Shigeru; Ando Zen-ichi; Kageyama Ryoichiro; Kawakami Kiyoshi
Six1 is essential for early neurogenesis in the development of olfactory epithelium.
Developmental biology 2007;311(1):53-68.
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2007: Niwa Yasutaka; Masamizu Yoshito; Liu Tianxiao; Nakayama Rika; Deng Chu-Xia; Kageyama Ryoichiro
The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock.
Developmental cell 2007;13(2):298-304.
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2007: Bai Ge; Sheng Nengyin; Xie Zhihui; Bian Wei; Yokota Yoshifumi; Benezra Robert; Kageyama Ryoichiro; Guillemot Francois; Jing Naihe
Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1.
Developmental cell 2007;13(2):283-97.
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2007: Yoshiura Shigeki; Ohtsuka Toshiyuki; Takenaka Yoshiko; Nagahara Hiroki; Yoshikawa Kenichi; Kageyama Ryoichiro
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(27):11292-7.
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2007: Kita Aya; Imayoshi Itaru; Hojo Masato; Kitagawa Masashi; Kokubu Hiroshi; Ohsawa Ryosuke; Ohtsuka Toshiyuki; Kageyama Ryoichiro; Hashimoto Nobuo
Hes1 and Hes5 control the progenitor pool, intermediate lobe specification, and posterior lobe formation in the pituitary development.
Molecular endocrinology (Baltimore, Md.) 2007;21(6):1458-66.
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2007: Kageyama Ryoichiro; Masamizu Yoshito; Niwa Yasutaka
Oscillator mechanism of Notch pathway in the segmentation clock.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(6):1403-9.
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2007: Kageyama Ryoichiro; Ohtsuka Toshiyuki; Kobayashi Taeko
The Hes gene family: repressors and oscillators that orchestrate embryogenesis.
Development (Cambridge, England) 2007;134(7):1243-51.
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2007: Karlsson Camilla; Jonsson Marianne; Asp Julia; Brantsing Camilla; Kageyama Ryoichiro; Lindahl Anders
Notch and HES5 are regulated during human cartilage differentiation.
Cell and tissue research 2007;327(3):539-51.
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2007: Kageyama R; Yoshiura S; Masamizu Y; Niwa Y
Ultradian oscillators in somite segmentation and other biological events.
Cold Spring Harbor symposia on quantitative biology 2007;72():451-7.
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2006: Zhu Xiaoyan; Zhang Jie; Tollkuhn Jessica; Ohsawa Ryosuke; Bresnick Emery H; Guillemot François; Kageyama Ryoichiro; Rosenfeld Michael G
Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.
Genes & development 2006;20(19):2739-53.
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2006: Forni Paolo E; Scuoppo Claudio; Imayoshi Itaru; Taulli Riccardo; Dastrù Walter; Sala Valentina; Betz Ulrich A K; Muzzi Patrizia; Martinuzzi Daniela; Vercelli Alessandro E; Kageyama Ryoichiro; Ponzetto Carola
High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(37):9593-602.
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2006: Hatakeyama Jun; Kageyama Ryoichiro
Notch1 expression is spatiotemporally correlated with neurogenesis and negatively regulated by Notch1-independent Hes genes in the developing nervous system.
Cerebral cortex (New York, N.Y. : 1991) 2006;16 Suppl 1():i132-7.
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2006: Baek Joung Hee; Hatakeyama Jun; Sakamoto Susumu; Ohtsuka Toshiyuki; Kageyama Ryoichiro
Persistent and high levels of Hes1 expression regulate boundary formation in the developing central nervous system.
Development (Cambridge, England) 2006;133(13):2467-76.
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2006: Kageyama Ryoichiro; Masamizu Yoshito
[Biological clock as a conductor for embryogenesis]
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(6):492-500.
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2006: Fukuda Akihisa; Kawaguchi Yoshiya; Furuyama Kenichiro; Kodama Sota; Horiguchi Masashi; Kuhara Takeshi; Koizumi Masayuki; Boyer Daniel F; Fujimoto Koji; Doi Ryuichiro; Kageyama Ryoichiro; Wright Christopher V E; Chiba Tsutomu
Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.
The Journal of clinical investigation 2006;116(6):1484-93.
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2006: Ikuta Koichi; Kageyama Ryoichiro; Honjo Tasuku
The 20th IUBMB International Congress in Kyoto.
IUBMB life 2006;58(5-6):258.
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2006: Imayoshi Itaru; Ohtsuka Toshiyuki; Metzger Daniel; Chambon Pierre; Kageyama Ryoichiro
Temporal regulation of Cre recombinase activity in neural stem cells.
Genesis (New York, N.Y. : 2000) 2006;44(5):233-8.
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2006: Moriyama Mariko; Osawa Masatake; Mak Siu-Shan; Ohtsuka Toshiyuki; Yamamoto Norio; Han Hua; Delmas Véronique; Kageyama Ryoichiro; Beermann Friedrich; Larue Lionel; Nishikawa Shin-Ichi
Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells.
The Journal of cell biology 2006;173(3):333-9.
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2006: Ong Chin-Tong; Cheng Hui-Teng; Chang Li-Wei; Ohtsuka Toshiyuki; Kageyama Ryoichiro; Stormo Gary D; Kopan Raphael
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability.
The Journal of biological chemistry 2006;281(8):5106-19.
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2006: Masamizu Yoshito; Ohtsuka Toshiyuki; Takashima Yoshiki; Nagahara Hiroki; Takenaka Yoshiko; Yoshikawa Kenichi; Okamura Hitoshi; Kageyama Ryoichiro
Real-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1313-8.
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2006: Ohtsuka Toshiyuki; Imayoshi Itaru; Shimojo Hiromi; Nishi Eiichiro; Kageyama Ryoichiro; McConnell Susan K
Visualization of embryonic neural stem cells using Hes promoters in transgenic mice.
Molecular and cellular neurosciences 2006;31(1):109-22.
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2006: Hatakeyama Jun; Sakamoto Susumu; Kageyama Ryoichiro
Hes1 and Hes5 regulate the development of the cranial and spinal nerve systems.
Developmental neuroscience 2006;28(1-2):92-101.
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2005: Masuda Kyoko; Kubagawa Hiromi; Ikawa Tomokatsu; Chen Ching-Cheng; Kakugawa Kiyokazu; Hattori Masakazu; Kageyama Ryoichiro; Cooper Max D; Minato Nagahiro; Katsura Yoshimoto; Kawamoto Hiroshi
Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors.
The EMBO journal 2005;24(23):4052-60.
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2005: Paquin Annie; Barnabé-Heider Fanie; Kageyama Ryoichiro; Miller Freda D
CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(46):10747-58.
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2005: Akagi Tadamichi; Akita Joe; Haruta Masatoshi; Suzuki Takuya; Honda Yoshihito; Inoue Tomoyuki; Yoshiura Shigeki; Kageyama Ryoichiro; Yatsu Takaaki; Yamada Masahiro; Takahashi Masayo
Iris-derived cells from adult rodents and primates adopt photoreceptor-specific phenotypes.
Investigative ophthalmology & visual science 2005;46(9):3411-9.
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2005: Ohsawa Ryosuke; Ohtsuka Toshiyuki; Kageyama Ryoichiro
Mash1 and Math3 are required for development of branchiomotor neurons and maintenance of neural progenitors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(25):5857-65.
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2005: Kageyama Ryoichiro; Ohtsuka Toshiyuki; Hatakeyama Jun; Ohsawa Ryosuke
Roles of bHLH genes in neural stem cell differentiation.
Experimental cell research 2005;306(2):343-8.
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2005: Vernay Bertrand; Koch Muriel; Vaccarino Flora; Briscoe James; Simeone Antonio; Kageyama Ryoichiro; Ang Siew-Lan
Otx2 regulates subtype specification and neurogenesis in the midbrain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(19):4856-67.
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2005: Murata Kaoru; Hattori Masakazu; Hirai Norihito; Shinozuka Yoriko; Hirata Hiromi; Kageyama Ryoichiro; Sakai Toshiyuki; Minato Nagahiro
Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1.
Molecular and cellular biology 2005;25(10):4262-71.
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2005: Suzuki Katsumasa; Fukui Hirokazu; Kayahara Takahisa; Sawada Mitsutaka; Seno Hiroshi; Hiai Hiroshi; Kageyama Ryoichiro; Okano Hideyuki; Chiba Tsutomu
Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine.
Biochemical and biophysical research communications 2005;328(1):348-52.
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2004: Kageyama Ryoichiro
[Developmental chronobiology: two-hour cycle biological clocks]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2004;49(17 Suppl):2939-42.
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2004: Kodama Yuzo; Hijikata Makoto; Kageyama Ryoichiro; Shimotohno Kunitada; Chiba Tsutomu
The role of notch signaling in the development of intrahepatic bile ducts.
Gastroenterology 2004;127(6):1775-86.
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2004: Akagi Tadamichi; Mandai Michiko; Ooto Sotaro; Hirami Yasuhiko; Osakada Fumitaka; Kageyama Ryoichiro; Yoshimura Nagahisa; Takahashi Masayo
Otx2 homeobox gene induces photoreceptor-specific phenotypes in cells derived from adult iris and ciliary tissue.
Investigative ophthalmology & visual science 2004;45(12):4570-5.
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2004: Hatakeyama Jun; Bessho Yasumasa; Katoh Kazuo; Ookawara Shigeo; Fujioka Makio; Guillemot François; Kageyama Ryoichiro
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation.
Development (Cambridge, England) 2004;131(22):5539-50.
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2004: Ooto Sotaro; Akagi Tadamichi; Kageyama Ryoichiro; Akita Joe; Mandai Michiko; Honda Yoshihito; Takahashi Masayo
Potential for neural regeneration after neurotoxic injury in the adult mammalian retina.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(37):13654-9.
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2004: Hirata Hiromi; Bessho Yasumasa; Kokubu Hiroshi; Masamizu Yoshito; Yamada Shuichi; Lewis Julian; Kageyama Ryoichiro
Instability of Hes7 protein is crucial for the somite segmentation clock.
Nature genetics 2004;36(7):750-4.
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2004: Akagi Tadamichi; Inoue Tomoyuki; Miyoshi Goichi; Bessho Yasumasa; Takahashi Masayo; Lee Jacqueline E; Guillemot François; Kageyama Ryoichiro
Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification.
The Journal of biological chemistry 2004;279(27):28492-8.
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2004: Kano Hideyuki; Arakawa Yoshiki; Takahashi Jun A; Nozaki Kazuhiko; Kawabata Yasuhiro; Takatsuka Kenji; Kageyama Ryoichiro; Ueba Tetsuya; Hashimoto Nobuo
Overexpression of RFT induces G1-S arrest and apoptosis via p53/p21(Waf1) pathway in glioma cell.
Biochemical and biophysical research communications 2004;317(3):902-8.
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2004: Miyoshi Goichi; Bessho Yasumasa; Yamada Shuichi; Kageyama Ryoichiro
Identification of a novel basic helix-loop-helix gene, Heslike, and its role in GABAergic neurogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(14):3672-82.
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2004: Takatsuka Kenji; Hatakeyama Jun; Bessho Yasumasa; Kageyama Ryoichiro
Roles of the bHLH gene Hes1 in retinal morphogenesis.
Brain research 2004;1004(1-2):148-55.
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2004: Tsunematsu Ryosuke; Nakayama Keiko; Oike Yuichi; Nishiyama Masaaki; Ishida Noriko; Hatakeyama Shigetsugu; Bessho Yasumasa; Kageyama Ryoichiro; Suda Toshio; Nakayama Keiichi I
Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.
The Journal of biological chemistry 2004;279(10):9417-23.
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2004: Hatakeyama Jun; Kageyama Ryoichiro
Retinal cell fate determination and bHLH factors.
Seminars in cell & developmental biology 2004;15(1):83-9.
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2004: Ohtsuka Toshiyuki; Kageyama Ryoichiro
[Mechanisms for maintenance and differentiation of neural stem cells]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2004;49(3 Suppl):234-40.
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2004: Sumazaki Ryo; Shiojiri Nobuyoshi; Isoyama Shigemi; Masu Masayuki; Keino-Masu Kazuko; Osawa Mitsujiro; Nakauchi Hiromitsu; Kageyama Ryoichiro; Matsui Akira
Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.
Nature genetics 2004;36(1):83-7.
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2003: Sakamoto Masami; Hirata Hiromi; Ohtsuka Toshiyuki; Bessho Yasumasa; Kageyama Ryoichiro
The basic helix-loop-helix genes Hesr1/Hey1 and Hesr2/Hey2 regulate maintenance of neural precursor cells in the brain.
The Journal of biological chemistry 2003;278(45):44808-15.
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2003: Tomita Shuhei; Ueno Masaki; Sakamoto Masami; Kitahama Yuki; Ueki Masaaki; Maekawa Nobuhiro; Sakamoto Haruhiko; Gassmann Max; Kageyama Ryoichiro; Ueda Natsuo; Gonzalez Frank J; Takahama Yousuke
Defective brain development in mice lacking the Hif-1alpha gene in neural cells.
Molecular and cellular biology 2003;23(19):6739-49.
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2003: Tateya Ichiro; Nakagawa Takayuki; Iguchi Fukuichiro; Kim Tae Soo; Endo Tsuyoshi; Yamada Shuichi; Kageyama Ryoichiro; Naito Yasushi; Ito Juichi
Fate of neural stem cells grafted into injured inner ears of mice.
Neuroreport 2003;14(13):1677-81.
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2003: Bessho Yasumasa; Kageyama Ryoichiro
Oscillations, clocks and segmentation.
Current opinion in genetics & development 2003;13(4):379-84.
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2003: Bessho Yasumasa; Hirata Hiromi; Masamizu Yoshito; Kageyama Ryoichiro
Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock.
Genes & development 2003;17(12):1451-6.
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2003: Kunisato Atsushi; Chiba Shigeru; Nakagami-Yamaguchi Etsuko; Kumano Keiki; Saito Toshiki; Masuda Shigeo; Yamaguchi Tomoyuki; Osawa Masatake; Kageyama Ryoichiro; Nakauchi Hiromitsu; Nishikawa Mitsuo; Hirai Hisamaru
HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo.
Blood 2003;101(5):1777-83.
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2003: Kayahara Takahisa; Sawada Mitsutaka; Takaishi Shigeo; Fukui Hirokazu; Seno Hiroshi; Fukuzawa Hiroaki; Suzuki Katsumasa; Hiai Hiroshi; Kageyama Ryoichiro; Okano Hideyuki; Chiba Tsutomu
Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine.
FEBS letters 2003;535(1-3):131-5.
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2003: Kageyama Ryoichiro; Hirata Hiromi; Hatakeyama Jun
Retroviral vectors for gene delivery to neural precursor cells.
International review of neurobiology 2003;55():123-47.
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2002: Hatakeyama Jun; Kageyama Ryoichiro
Retrovirus-mediated gene transfer to retinal explants.
Methods (San Diego, Calif.) 2002;28(4):387-95.
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2002: Hirata Hiromi; Yoshiura Shigeki; Ohtsuka Toshiyuki; Bessho Yasumasa; Harada Takahiro; Yoshikawa Kenichi; Kageyama Ryoichiro
Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop.
Science (New York, N.Y.) 2002;298(5594):840-3.
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2002: Akiba Tsugino; Kuroiwa Namiko; Shimizu-Yabe Atsuko; Iwase Katsuro; Hiwasa Takaki; Yokoe Hidetaka; Kubosawa Hitoshi; Kageyama Ryoichiro; Darlington Gretchen J; Mori Masataka; Tanzawa Hideki; Takiguchi Masaki;
Expression and regulation of the gene for arginase I in mouse salivary glands: requirement of CCAAT/enhancer-binding protein alpha for the expression in the parotid gland.
Journal of biochemistry 2002;132(4):621-7.
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2002: Inoue Tomoyuki; Hojo Masato; Bessho Yasumasa; Tano Yasuo; Lee Jacqueline E; Kageyama Ryoichiro
Math3 and NeuroD regulate amacrine cell fate specification in the retina.
Development (Cambridge, England) 2002;129(4):831-42.
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2001: Haruta M; Kosaka M; Kanegae Y; Saito I; Inoue T; Kageyama R; Nishida A; Honda Y; Takahashi M
Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue.
Nature neuroscience 2001;4(12):1163-4.
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2001: Inoue C; Bae S K; Takatsuka K; Inoue T; Bessho Y; Kageyama R
Math6, a bHLH gene expressed in the developing nervous system, regulates neuronal versus glial differentiation.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(11):977-86.
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2001: Bessho Y; Sakata R; Komatsu S; Shiota K; Yamada S; Kageyama R
Dynamic expression and essential functions of Hes7 in somite segmentation.
Genes & development 2001;15(20):2642-7.
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2001: Hirata H; Tomita K; Bessho Y; Kageyama R
Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.
The EMBO journal 2001;20(16):4454-66.
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2001: Ohtsuka T; Sakamoto M; Guillemot F; Kageyama R
Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain.
The Journal of biological chemistry 2001;276(32):30467-74.
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2001: Hatakeyama J; Tomita K; Inoue T; Kageyama R
Roles of homeobox and bHLH genes in specification of a retinal cell type.
Development (Cambridge, England) 2001;128(8):1313-22.
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2001: Bessho Y; Miyoshi G; Sakata R; Kageyama R
Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(2):175-85.
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2001: Satow T; Bae S K; Inoue T; Inoue C; Miyoshi G; Tomita K; Bessho Y; Hashimoto N; Kageyama R
The basic helix-loop-helix gene hesr2 promotes gliogenesis in mouse retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(4):1265-73.
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2000: Tomita K; Moriyoshi K; Nakanishi S; Guillemot F; Kageyama R
Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system.
The EMBO journal 2000;19(20):5460-72.
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2000: Bae S; Bessho Y; Hojo M; Kageyama R
The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation.
Development (Cambridge, England) 2000;127(13):2933-43.
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2000: Kageyama R
[Regulation of neuronal differentiation by bHLH factors]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1605-11.
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2000: Kageyama R
[Regulatory mechanisms and transcription factors for cell differentiation and body morphogenesis]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1603-4.
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2000: Hirata H; Ohtsuka T; Bessho Y; Kageyama R
Generation of structurally and functionally distinct factors from the basic helix-loop-helix gene Hes3 by alternative first exons.
The Journal of biological chemistry 2000;275(25):19083-9.
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2000: Hojo M; Ohtsuka T; Hashimoto N; Gradwohl G; Guillemot F; Kageyama R
Glial cell fate specification modulated by the bHLH gene Hes5 in mouse retina.
Development (Cambridge, England) 2000;127(12):2515-22.
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2000: Cau E; Gradwohl G; Casarosa S; Kageyama R; Guillemot F
Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium.
Development (Cambridge, England) 2000;127(11):2323-32.
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2000: Kageyama R; Ohtsuka T
[Notch pathway in neural development]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(3 Suppl):221-6.
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1999: Kageyama R; Ohtsuka T
The Notch-Hes pathway in mammalian neural development.
Cell research 1999;9(3):179-88.
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1999: Isaka F; Ishibashi M; Taki W; Hashimoto N; Nakanishi S; Kageyama R
Ectopic expression of the bHLH gene Math1 disturbs neural development.
The European journal of neuroscience 1999;11(7):2582-8.
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1999: Tomita K; Hattori M; Nakamura E; Nakanishi S; Minato N; Kageyama R
The bHLH gene Hes1 is essential for expansion of early T cell precursors.
Genes & development 1999;13(9):1203-10.
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1999: Ohtsuka T; Ishibashi M; Gradwohl G; Nakanishi S; Guillemot F; Kageyama R
Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.
The EMBO journal 1999;18(8):2196-207.
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1999: Konishi Y; Ohkawa N; Makino Y; Ohkubo H; Kageyama R; Furuichi T; Mikoshiba K; Tamura T
Transcriptional regulation of mouse type 1 inositol 1,4,5-trisphosphate receptor gene by NeuroD-related factor.
Journal of neurochemistry 1999;72(4):1717-24.
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1998: Ohtsuka T; Asahi M; Matsuura N; Kikuchi H; Hojo M; Kageyama R; Ohkubo H; Hoshimaru M
Regulated expression of neurogenic basic helix-loop-helix transcription factors during differentiation of the immortalized neuronal progenitor cell line HC2S2 into neurons.
Cell and tissue research 1998;293(1):23-9.
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1998: Kageyama R
[Neurosurgery and molecular biology: (series 3) molecular biology of the brain-neurons]
No shinkei geka. Neurological surgery 1998;26(5):385-90.
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1998: Nishimura M; Isaka F; Ishibashi M; Tomita K; Tsuda H; Nakanishi S; Kageyama R
Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split.
Genomics 1998;49(1):69-75.
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1998: Tsuda H; Takebayashi K; Nakanishi S; Kageyama R
Structure and promoter analysis of Math3 gene, a mouse homolog of Drosophila proneural gene atonal. Neural-specific expression by dual promoter elements.
The Journal of biological chemistry 1998;273(11):6327-33.
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1997: Kageyama R; Ishibashi M; Takebayashi K; Tomita K
bHLH transcription factors and mammalian neuronal differentiation.
The international journal of biochemistry & cell biology 1997;29(12):1389-99.
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1997: Kageyama R; Nakanishi S
Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system.
Current opinion in genetics & development 1997;7(5):659-65.
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1997: Takebayashi K; Takahashi S; Yokota C; Tsuda H; Nakanishi S; Asashima M; Kageyama R
Conversion of ectoderm into a neural fate by ATH-3, a vertebrate basic helix-loop-helix gene homologous to Drosophila proneural gene atonal.
The EMBO journal 1997;16(2):384-95.
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1996: Isaka F; Shimizu C; Nakanishi S; Kageyama R
Genetic mapping of four mouse bHLH genes related to Drosophila proneural gene atonal.
Genomics 1996;37(3):400-2.
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1996: Kageyama R; Ishibashi M; Takebayashi K; Tomita K
[Helix-loop-helix transcription factor network regulating mammalian neurogenesis]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(8 Suppl):989-96.
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1996: Tomita K; Ishibashi M; Nakahara K; Ang S L; Nakanishi S; Guillemot F; Kageyama R
Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis.
Neuron 1996;16(4):723-34.
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1995: Ishibashi M; Ang S L; Shiota K; Nakanishi S; Kageyama R; Guillemot F
Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects.
Genes & development 1995;9(24):3136-48.
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1995: Kageyama R
[Regulation of neural differentiation by HES helix-loop-helix transcription factors]
Seikagaku. The Journal of Japanese Biochemical Society 1995;67(9):1093-114.
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1995: Shimizu C; Akazawa C; Nakanishi S; Kageyama R
MATH-2, a mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal, is specifically expressed in the nervous system.
European journal of biochemistry / FEBS 1995;229(1):239-48.
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1995: Akazawa C; Ishibashi M; Shimizu C; Nakanishi S; Kageyama R
A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system.
The Journal of biological chemistry 1995;270(15):8730-8.
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1995: Takebayashi K; Akazawa C; Nakanishi S; Kageyama R
Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5. Identification of the neural precursor cell-specific promoter element.
The Journal of biological chemistry 1995;270(3):1342-9.
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1995: Kageyama R; Sasai Y; Akazawa C; Ishibashi M; Takebayashi K; Shimizu C; Tomita K; Nakanishi S
Regulation of mammalian neural development by helix-loop-helix transcription factors.
Critical reviews in neurobiology 1995;9(2-3):177-88.
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1994: Sakagami T; Sakurada K; Sakai Y; Watanabe T; Nakanishi S; Kageyama R
Structure and chromosomal locus of the mouse gene encoding a cerebellar Purkinje cell-specific helix-loop-helix factor Hes-3.
Biochemical and biophysical research communications 1994;203(1):594-601.
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1994: Ishibashi M; Moriyoshi K; Sasai Y; Shiota K; Nakanishi S; Kageyama R
Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system.
The EMBO journal 1994;13(8):1799-805.
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1994: Takebayashi K; Sasai Y; Sakai Y; Watanabe T; Nakanishi S; Kageyama R
Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements.
The Journal of biological chemistry 1994;269(7):5150-6.
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1993: Ishibashi M; Sasai Y; Nakanishi S; Kageyama R
Molecular characterization of HES-2, a mammalian helix-loop-helix factor structurally related to Drosophila hairy and Enhancer of split.
European journal of biochemistry / FEBS 1993;215(3):645-52.
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1992: Sasai Y; Kageyama R; Tagawa Y; Shigemoto R; Nakanishi S
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.
Genes & development 1992;6(12B):2620-34.
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1992: Akazawa C; Sasai Y; Nakanishi S; Kageyama R
Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system.
The Journal of biological chemistry 1992;267(30):21879-85.
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1991: Kageyama R; Sasai Y; Nakanishi S
Molecular characterization of transcription factors that bind to the cAMP responsive region of the substance P precursor gene. cDNA cloning of a novel C/EBP-related factor.
The Journal of biological chemistry 1991;266(23):15525-31.
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