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S Kahn

Research Profile

Chemicals & Drugs

Disorders

Anatomy

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TOP 3
Y Luo; Brad Bolon; S Kahn; BD Bennett; Safura Babu-Khan; Paul E Denis; W Fan; H Kha; J Zhang; Y Gong; L Martin; Jean-Claude Louis; Q Yan; William G Richards; Martin Citron; Robert Vassar
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
BD Bennett; Paul E Denis; Mitsuru Haniu; David B Teplow; S Kahn; Jean-Claude Louis; Martin Citron; Robert Vassar
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase.
Mitsuru Haniu; Paul E Denis; Yunjen Young; E A Mendiaz; J Fuller; JO Hui; BD Bennett; S Kahn; S Ross; TL Burgess; V Katta; Gary A Rogers; Robert Vassar; Martin Citron
Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties.

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All Publications

2001: Y Luo; Brad Bolon; S Kahn; BD Bennett; Safura Babu-Khan; Paul E Denis; W Fan; H Kha; J Zhang; Y Gong; L Martin; Jean-Claude Louis; Q Yan; William G Richards; Martin Citron; Robert Vassar
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
Nature neuroscience 2001;4(3):231-2.
2000: BD Bennett; Paul E Denis; Mitsuru Haniu; David B Teplow; S Kahn; Jean-Claude Louis; Martin Citron; Robert Vassar
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase.
The Journal of biological chemistry 2000;275(48):37712-7.
2000: Mitsuru Haniu; Paul E Denis; Yunjen Young; E A Mendiaz; J Fuller; JO Hui; BD Bennett; S Kahn; S Ross; TL Burgess; V Katta; Gary A Rogers; Robert Vassar; Martin Citron
Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties.
The Journal of biological chemistry 2000;275(28):21099-106.
2000: G M Rishton; D M Retz; P A Tempest; J Novotny; S Kahn; James J S Treanor; Jack Lile; Martin Citron
Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: potential small-molecule therapeutic agents for the treatment of Alzheimer's disease.
Journal of medicinal chemistry 2000;43(12):2297-9.
1999: Robert Vassar; BD Bennett; Safura Babu-Khan; S Kahn; E A Mendiaz; Paul E Denis; David B Teplow; S Ross; P Amarante; R Loeloff; Y Luo; S Fisher; J Fuller; S Edenson; Jack Lile; Mark Jarosinski; Anja Leona Biere; E Curran; TL Burgess; Jean-Claude Louis; F Collins; James J S Treanor; G Rogers; Martin Citron
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Science (New York, N.Y.) 1999;286(5440):735-41.