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Timo Kaila
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17
Huupponen, Risto
15
Kuusela, Tom
15
Tahvanainen, Kari
14
Salminen, Lotta
12
Kanto, Jussi
9
Jartti, Tuomas
7
Vuori, Marja-Liisa
7
Saari, Matti
6
Vesalainen, Risto
6
Kentala, Erkki
5
Kantola, Ilkka
5
Välimäki, IA
4
Vanto, Timo
4
Scheinin, Harry
3
Scheinin, Mika
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All Publications
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2005: Lepoluoto A; Nino J; Tahvanainen K; Ylitalo R; Kuusela T; Kähönen M; Kaila T
Propranolol increases the complexity of heart rate fluctuations--a mode of antiarrhythmic action?
International journal of clinical pharmacology and therapeutics 2005;43(2):101-8.
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2005: Kuusela Tom A; Jartti Tuomas T; Tahvanainen Kari U O; Kaila Timo J
Prolongation of QT interval by terbutaline in healthy subjects.
Journal of cardiovascular pharmacology 2005;45(2):175-81.
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2004: Penttilä J; Kaila T; Helminen A; Anttila M; Karhuvaara S; Huhtala S; Scheinin H
Effects of atipamezole--a selective alpha-adrenoceptor antagonist--on cardiac parasympathetic regulation in human subjects.
Autonomic & autacoid pharmacology 2004;24(3):69-75.
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2004: Kuusela Tom A; Jartti Tuomas T; Tahvanainen Kari U O; Kaila Timo J
Effects of terbutaline on peripheral vascular resistance and arterial compliance.
Journal of cardiovascular pharmacology 2004;44(1):74-81.
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2003: Kuusela Tom A; Kaila Timo J; Kähönen Mika
Fine structure of the low-frequency spectra of heart rate and blood pressure.
BMC physiology 2003;3():11.
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2002: Niño J; Tahvanainen K; Uusitalo H; Turjanmaa V; Hutri-Kähönen N; Kaila T; Ropo A; Kuusela T; Kähönen M
Cardiovascular effects of ophthalmic 0.5% timolol aqueous solution and 0.1% timolol hydrogel.
Clinical physiology and functional imaging 2002;22(4):271-8.
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2002: Korte Juha-Matti; Kaila Timo; Saari K Matti
Systemic bioavailability and cardiopulmonary effects of 0.5% timolol eyedrops.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2002;240(6):430-5.
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2002: Kuusela Tom A; Jartti Tuomas T; Tahvanainen Kari U O; Kaila Timo J
Nonlinear methods of biosignal analysis in assessing terbutaline-induced heart rate and blood pressure changes.
American journal of physiology. Heart and circulatory physiology 2002;282(2):H773-83.
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2001: Penttilä J; Vesalainen R; Helminen A; Kuusela T; Hinkka S; Rahi K; Kaila T; Scheinin H
Spontaneous baroreflex sensitivity as a dynamic measure of cardiac anticholinergic drug effect.
Journal of autonomic pharmacology 2001;21(2):71-8.
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1999: Kaila T; Korte J M; Saari K M
Systemic bioavailability of ocularly applied 1% atropine eyedrops.
Acta ophthalmologica Scandinavica 1999;77(2):193-6.
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1999: Scheinin H; Helminen A; Huhtala S; Grönroos P; Bosch J A; Kuusela T; Kanto J; Kaila T
Spectral analysis of heart rate variability as a quantitative measure of parasympatholytic effect--integrated pharmacokinetics and pharmacodynamics of three anticholinergic drugs.
Therapeutic drug monitoring 1999;21(2):141-51.
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1999: Vesalainen R K; Ekholm E M; Jartti T T; Tahvanainen K U; Kaila T J; Erkkola R U
Effects of tocolytic treatment with ritodrine on cardiovascular autonomic regulation.
British journal of obstetrics and gynaecology 1999;106(3):238-43.
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1998: Rautakorpi P; Manner T; Ali-Melkkilä T; Kaila T; Olkkola K; Kanto J
Pharmacokinetics and oral bioavailability of glycopyrrolate in children.
Pharmacology & toxicology 1998;83(3):132-4.
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1998: Vainio-Jylhä E; Vuori M L; Kaila T; Huupponen R
Aqueous humour concentration and the intraocular pressure-lowering effect of topical betaxolol before cataract surgery.
European journal of clinical pharmacology 1998;54(5):389-92.
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1998: Jartti T T; Kaila T J; Tahvanainen K U; Kuusela T A; Vanto T T; Välimäki I A
Altered cardiovascular autonomic regulation after salmeterol treatment in asthmatic children.
Clinical physiology (Oxford, England) 1998;18(4):345-53.
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1998: Vesalainen R K; Kantola I M; Airaksinen K E; Tahvanainen K U; Kaila T J
Vagal cardiac activity in essential hypertension: the effects of metoprolol and ramipril.
American journal of hypertension 1998;11(6 Pt 1):649-58.
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1998: Vesalainen R K; Kaila T J; Kantola I M; Tahvanainen K U; Juhani Airaksinen K E; Kuusela T A; Eckberg D L
Low-dose transdermal scopolamine decreases blood pressure in mild essential hypertension.
Journal of hypertension 1998;16(3):321-9.
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1998: Kentala E; Scheinin H; Kaila T; Seppälä T; Kanto J
Pharmacokinetics and clinical effects of intramuscular scopolamine plus morphine. A comparison of two injection sites.
Acta anaesthesiologica Scandinavica 1998;42(3):323-8.
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1998: Jartti T T; Kuusela T A; Kaila T J; Tahvanainen K U; Välimäki I A
The dose-response effects of terbutaline on the variability, approximate entropy and fractal dimension of heart rate and blood pressure.
British journal of clinical pharmacology 1998;45(3):277-85.
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1998: Ekholm E M; Vesalainen R K; Tahvanainen K U; Kaila T; Erkkola R U
Valsalva manoeuvre can be used to study baroreflex sensitivity in pregnancy.
European journal of obstetrics, gynecology, and reproductive biology 1998;76(2):153-6.
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1998: Haaga M; Kaila T; Salminen L; Ylitalo P
Systemic and ocular absorption and antagonist activity of topically applied cyclopentolate in man.
Pharmacology & toxicology 1998;82(1):19-22.
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1997: Jartti T T; Kaila T J; Tahvanainen K U; Kuusela T A; Vanto T T; Välimäki I A
Altered cardiovascular autonomic regulation after 2-week inhaled salbutamol treatment in asthmatic children.
European journal of pediatrics 1997;156(11):883-8.
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1997: Jartti T; Kaila T; Tahvanainen K; Kuusela T; Vanto T; Välimäki I
The acute effects of inhaled salbutamol on the beat-to-beat variability of heart rate and blood pressure assessed by spectral analysis.
British journal of clinical pharmacology 1997;43(4):421-8.
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1997: Vesalainen R K; Tahvanainen K U; Kaila T J; Kantola I M; Kuusela T A; Eckberg D L
Effects of low-dose transdermal scopolamine on autonomic cardiovascular control in healthy young subjects.
Clinical physiology (Oxford, England) 1997;17(2):135-48.
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1996: Jartti T T; Tahvanainen K U; Kaila T J; Kuusela T A; Koivikko A S; Vanto T T; Välimäki I A
Cardiovascular autonomic regulation in asthmatic children evidenced by spectral analysis of heart rate and blood pressure variability.
Scandinavian journal of clinical and laboratory investigation 1996;56(6):545-54.
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1996: Laine V J; Huupponen R; Kaila T; Gronroos J; Nevalainen T J
Muscarinic receptors and insulin concentration in the rat pancreas after chronic alcohol intake and cholinergic stimulation.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1996;48(1):77-9.
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1996: Kantola I; Tarssanen L; Scheinin M; Ruskoaho H; Viinamäki O; Kaila T
beta-blockade, atrial natriuretic peptide and exercise.
International journal of clinical pharmacology and therapeutics 1996;34(1):12-6.
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1995: Vuori M L; Kaila T
Plasma kinetics and antagonist activity of topical ocular timolol in elderly patients.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1995;233(3):131-4.
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1994: Lahdes K K; Huupponen R K; Kaila T J
Ocular effects and systemic absorption of cyclopentolate eyedrops after canthal and conventional application.
Acta ophthalmologica 1994;72(6):698-702.
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1994: Grönroos J M; Laine J; Kaila T; Nevalainen T J
Chronic alcohol intake and carbachol-induced acute pancreatitis in the rat.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1994;46(2):163-7.
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1994: Rautakorpi P; Ali-Melkkilä T; Kaila T; Olkkola K T; Iisalo E; Iisalo E; Kanto J
Pharmacokinetics of glycopyrrolate in children.
Journal of clinical anesthesia 1994;6(3):217-20.
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1994: Grönroos J M; Kaila T; Hietaranta A J
Alcohol, pancreatic muscarinic receptors and acute pancreatitis.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1994;45(8):503-5.
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1994: Kantola I; Kaila T; Erkkola R
Acute exercise- and drug-induced potassium shifts during pregnancy.
Annales chirurgiae et gynaecologiae. Supplementum 1994;208():88-90.
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1994: Vuori M L; Kaila T; Iisalo E; Saari K M
Systemic absorption and anticholinergic activity of topically applied tropicamide.
Journal of ocular pharmacology 1994;10(2):431-7.
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1994: Kaila T; Roivas L; Neuvonen P J
Receptor binding assays in analysing the bioavailability and pharmacodynamic bioequivalence of active drug moieties. A study of metoprolol.
European journal of clinical pharmacology 1994;46(3):237-42.
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1994: Alihanka J; Lahdenperä A; Kaila T
The effects of transdermal scopolamine on autonomic nervous activity during sleep.
European journal of clinical pharmacology 1994;46(6):507-10.
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1993: Kaila T; Iisalo E; Lehtonen A; Saarimaa H
Extent of beta 1- and beta 2-receptor occupancy in plasma assesses the antagonist activity of metoprolol, pindolol, and propranolol in the elderly.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1993;7(6):839-49.
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1993: Kaila T; Iisalo E
Selectivity of acebutolol, atenolol, and metoprolol in healthy volunteers estimated by the extent the drugs occupy beta 2-receptors in the circulating plasma.
Journal of clinical pharmacology 1993;33(10):959-66.
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1993: Vuori M L; Ali-Melkkilä T; Kaila T; Iisalo E; Saari K M
Beta 1- and beta 2-antagonist activity of topically applied betaxolol and timolol in the systemic circulation.
Acta ophthalmologica 1993;71(5):682-5.
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1993: Vuori M L; Kaila T; Iisalo E; Saari K M
Concentrations and antagonist activity of topically applied betaxolol in aqueous humour.
Acta ophthalmologica 1993;71(5):677-81.
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1993: Saari K M; Ali-Melkkilä T; Vuori M L; Kaila T; Iisalo E
Absorption of ocular timolol: drug concentrations and beta-receptor binding activity in the aqueous humour of the treated and contralateral eye.
Acta ophthalmologica 1993;71(5):671-6.
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1993: Kirvelä M; Ali-Melkkilä T; Kaila T; Iisalo E; Lindgren L
Pharmacokinetics of glycopyrronium in uraemic patients.
British journal of anaesthesia 1993;71(3):437-9.
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1993: Kaila T; Karhuvaara S; Huupponen R; Iisalo E
The analysis of plasma kinetics and beta-receptor binding and -blocking activity of timolol following its small intravenous dose.
International journal of clinical pharmacology, therapy, and toxicology 1993;31(7):351-7.
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1993: Lahdes K; Huupponen R; Kaila T; Monti D; Saettone M F; Salminen L
Plasma concentrations and ocular effects of cyclopentolate after ocular application of three formulations.
British journal of clinical pharmacology 1993;35(5):479-83.
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1993: Kaila T; Marttila R
Receptor occupancy in lumbar CSF as a measure of the antagonist activity of atenolol, metoprolol and propranolol in the CNS.
British journal of clinical pharmacology 1993;35(5):507-15.
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1993: Vuori M L; Ali-Melkkilä T; Kaila T; Iisalo E; Saari K M
Plasma and aqueous humour concentrations and systemic effects of topical betaxolol and timolol in man.
Acta ophthalmologica 1993;71(2):201-6.
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1992: Lahdes K; Huupponen R; Kaila T; Ali-Melkkilä T; Salminen L; Saari M
Systemic absorption of ocular cyclopentolate in children.
German journal of ophthalmology 1992;1(1):16-8.
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1992: Huupponen R; Kaila T; Saettone M F; Monti D; Ilsalo E; Salminen L; Oksala O
The effect of some macromolecular ionic complexes on the pharmacokinetics and -dynamics of ocular cyclopentolate in rabbits.
Journal of ocular pharmacology 1992;8(1):59-67.
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1991: Ali-Melkkilä T; Kaila T; Antila K; Halkola L; Iisalo E
Effects of glycopyrrolate and atropine on heart rate variability.
Acta anaesthesiologica Scandinavica 1991;35(5):436-41.
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1991: Kentala E; Kaila T; Arola M; Mattila M; Kanto J
Pharmacokinetics and clinical response of hyoscine plus morphine premedication in connection with cardiopulmonary bypass surgery.
European journal of anaesthesiology 1991;8(2):135-40.
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1991: Kaila T
A sensitive radioligand binding assay for timolol in plasma.
Journal of pharmaceutical sciences 1991;80(3):296-9.
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1991: Kaila T; Huupponen R; Karhuvaara S; Havula P; Scheinin M; Iisalo E; Salminen L
Beta-blocking effects of timolol at low plasma concentrations.
Clinical pharmacology and therapeutics 1991;49(1):53-8.
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1991: Huupponen R; Kaila T; Lahdes K; Salminen L; Iisalo E
Systemic absorption of ocular timolol in poor and extensive metabolizers of debrisoquine.
Journal of ocular pharmacology 1991;7(2):183-7.
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1990: Kentala E; Kaila T; Ali-Melkkilä T; Kanto J
beta-Glucuronide and sulfate conjugation of scopolamine and glycopyrrolate.
International journal of clinical pharmacology, therapy, and toxicology 1990;28(11):487-9.
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1990: Kaila T; Ali-Melkkilä T; Iisalo E; Kanto J
Radioreceptor assay for pharmacokinetic studies of glycopyrrolate.
Pharmacology & toxicology 1990;67(4):313-6.
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1990: Kentala E; Kaila T; Iisalo E; Kanto J
Intramuscular atropine in healthy volunteers: a pharmacokinetic and pharmacodynamic study.
International journal of clinical pharmacology, therapy, and toxicology 1990;28(9):399-404.
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1990: Ali-Melkkilä T; Kaila T; Kanto J; Iisalo E
Pharmacokinetics of glycopyrronium in parturients.
Anaesthesia 1990;45(8):634-7.
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1990: Ali-Melkkilä T M; Kaila T; Kanto J; Iisalo E
Pharmacokinetics of i.m. glycopyrronium.
British journal of anaesthesia 1990;64(6):667-9.
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1990: Kaila T; Suonpää J; Grénman R; Iisalo E
Vasomotor rhinitis and the systemic absorption of ipratropium bromide.
Rhinology 1990;28(2):83-9.
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1990: Lahdes K; Huupponen R; Kaila T; Salminen L; Iisalo E
Systemic absorption of ocular scopolamine in patients.
Journal of ocular pharmacology 1990;6(1):61-6.
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1989: Karhuvaara S; Kaila T; Huupponen R
Beta-adrenoceptor antagonist activities and binding affinities of timolol enantiomers in rat atria.
The Journal of pharmacy and pharmacology 1989;41(9):649-50.
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1989: Kentala E; Kaila T; Kanto J
Intramuscular atropine in elderly people: pharmacokinetic studies using the radioreceptor assay and some pharmacodynamic responses.
Pharmacology & toxicology 1989;65(2):110-3.
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1989: Aula P; Kaila T; Huupponen R; Salminen L; Iisalo E
Prostaglandin F2 alpha binding to bovine ocular and synthetic melanins in vitro.
Pharmacology & toxicology 1989;65(2):100-3.
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1989: Ali-Melkkilä T; Kaila T; Kanto J
Glycopyrrolate: pharmacokinetics and some pharmacodynamic findings.
Acta anaesthesiologica Scandinavica 1989;33(6):513-7.
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1989: Kanto J; Kentala E; Kaila T; Pihlajamäki K
Pharmacokinetics of scopolamine during caesarean section: relationship between serum concentration and effect.
Acta anaesthesiologica Scandinavica 1989;33(6):482-6.
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1989: Salonen M; Forssell H; Lehmijoki O; Kaila T; Scheinin M
A comparison of two sedative premedications for minor oral surgery under local anaesthesia.
International journal of oral and maxillofacial surgery 1989;18(4):202-5.
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1989: Kaila T; Huupponen R; Salminen L; Iisalo E
Systemic absorption of ophthalmic cyclopentolate.
American journal of ophthalmology 1989;107(5):562-4.
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1989: Grönroos J M; Kaila T; Aho H J; Nevalainen T J
Decrease in the number of muscarinic receptors in rat pancreas after chronic alcohol intake.
Pharmacology & toxicology 1989;64(4):356-9.
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1989: Salminen L; Lindberg R; Toivari H R; Huupponen R; Kaila T; Iisalo E
Prevalence of debrisoquine oxidation phenotypes in glaucoma patients.
International ophthalmology 1989;13(1-2):91-3.
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1988: Lahdes K; Kaila T; Huupponen R; Salminen L; Iisalo E
Systemic absorption of topically applied ocular atropine.
Clinical pharmacology and therapeutics 1988;44(3):310-4.
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1988: Laurikainen E; Koulu M; Kaila T; Scheinin M; Isalo E
Evaluation of the systemic anticholinergic activity of nasally administered ipratropium bromide.
Rhinology 1988;26(2):133-8.
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1988: Laurikainen K; Laurikainen E; Tenovuo J; Kaila T; Vilja P
Effects of a beta-blocking agent, timolol maleate, on saliva in healthy volunteers.
Scandinavian journal of dental research 1988;96(2):121-7.
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1988: Iisalo E; Kaila T; Laurén L
Radioreceptor assay of anticholinergic drugs.
Annals of clinical research 1988;20(5):367-72.
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1988: Aula P; Kaila T; Huupponen R; Salminen L
Timolol binding to bovine ocular melanin in vitro.
Journal of ocular pharmacology 1988;4(1):29-36.
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1988: Kaila T; Penttinen R; Peltonen J
Cultured neurofibromatosis tumor fibroblasts lack beta-adrenergic receptors.
Neurofibromatosis 1988;1(1):37-42.
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1986: Kaila T; Huupponen R; Salminen L
Effects of eyelid closure and nasolacrimal duct occlusion on the systemic absorption of ocular timolol in human subjects.
Journal of ocular pharmacology 1986;2(4):365-9.
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1985: Kaila T; Salminen L; Huupponen R
Systemic absorption of topically applied ocular timolol.
Journal of ocular pharmacology 1985;1(1):79-83.
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