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Jan Kajstura

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Anatomy

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Matthew Schoenfeld; William H Frishman; Jan Kajstura; Annarosa Leri; Piero Anversa
The existence of myocardial repair: mechanistic insights and enhancements.
Piero Anversa; Jan Kajstura; Marcello Rota; Annarosa Leri
Regenerating new heart with stem cells.
Frederick G P Welt; Ravi Shah; Piero Anversa; Otavio Coelho-Filho; John Connell; Domenico D'Amario; Lori Foley; Robert Gallegos; Jan Kajstura; Raymond Y Kwong; Annarosa Leri; Richard Mitchell; Marc A Pfeffer
Effect of cardiac stem cells on left-ventricular remodeling in a canine model of chronic myocardial infarction.

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All Publications

2013: Matthew Schoenfeld; William H Frishman; Jan Kajstura; Annarosa Leri; Piero Anversa
The existence of myocardial repair: mechanistic insights and enhancements.
Cardiology in review 2013;21(3):111-20.
2013: Piero Anversa; Jan Kajstura; Marcello Rota; Annarosa Leri
Regenerating new heart with stem cells.
The Journal of clinical investigation 2013;123(1):62-70.
2013: Frederick G P Welt; Ravi Shah; Piero Anversa; Otavio Coelho-Filho; John Connell; Domenico D'Amario; Lori Foley; Robert Gallegos; Jan Kajstura; Raymond Y Kwong; Annarosa Leri; Richard Mitchell; Marc A Pfeffer
Effect of cardiac stem cells on left-ventricular remodeling in a canine model of chronic myocardial infarction.
Circulation. Heart failure 2013;6(1):99-106.
2012: Richard K Burt; James Carr; You-hong Chen; Xiaoqiang Han; Jesse Johnson; Jan Kajstura; Aya Kino; JW Lomasney; Carolina Lucena; Shankararao Navale; Ka-Leung Ngai; Larissa Verda; Jessa M Baker; Piero Anversa
Mitotically inactivated embryonic stem cells can be used as an in vivo feeder layer to nurse damaged myocardium after acute myocardial infarction: a preclinical study.
Circulation research 2012;111(10):1286-96.
2012: Jan Kajstura; James Kostyla; Annarosa Leri; Joseph Loscalzo; Alex Matsuda; Robert E Michler; Barbara Ogórek; Mark A Perrella; Marcello Rota; Fumihiro Sanada; Sergio Signore; Christian Arranto; Yingnan Bai; Bruce A Buchholz; Maria-Virginia Caballero; Donato Cappetta; David A D'Alessandro; Federica del Monte; João Ferreira-Martins; Claudia Fiorini; Toru Hosoda; Piero Anversa
Cardiomyogenesis in the aging and failing human heart.
Circulation 2012;126(15):1869-81.
2012: Jan Kajstura; Junghyun Kim; Annarosa Leri; Joseph Loscalzo; Alex Matsuda; Marcello Rota; Fumihiro Sanada; Christian Arranto; Yingnan Bai; Silvana Bardelli; Donato Cappetta; D'Amario Domenico; João Ferreira-Martins; Toru Hosoda; Piero Anversa
Tracking chromatid segregation to identify human cardiac stem cells that regenerate extensively the infarcted myocardium.
Circulation research 2012;111(7):894-906.
2012: Atul R Chugh; Julius B Elmore; Jan Kajstura; João A C Lima; John H Loughran; Nathan Mewton; Patroklos Pappas; Mark S Slaughter; Marcus F Stoddard; Antone J Tatooles; Piero Anversa; Garth M Beache; Roberto Bolli
Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance.
Circulation 2012;126(11 Suppl 1):S54-64.
2012: Annarosa Leri; Jan Kajstura
Created equal? The many facets of cell reprogramming.
Circulation research 2012;111(2):152-5.
2012: Piero Anversa; Annarosa Leri; Jan Kajstura
Biased DNA segregation during stem cell division.
Circulation research 2012;110(11):1403-7.
2012: João Ferreira-Martins; Toru Hosoda; Grazia Iaffaldano; Noriko Ide-Iwata; Jan Kajstura; James Kostyla; Annarosa Leri; Alex Matsuda; Barbara Ogórek; Sergio Ottolenghi; Piero Anversa; Donato Cappetta; D'Amario Domenico; Fumihiro Sanada; Sergio Signore; Elisabeth Steadman; Marcello Rota
Cardiomyogenesis in the developing heart is regulated by c-kit-positive cardiac stem cells.
Circulation research 2012;110(5):701-15.
2011: Roberto Bolli; Donato Cappetta; Atul R Chugh; Domenico D'Amario; Julius B Elmore; Ibrahim Fahsah; Polina Goichberg; Toru Hosoda; Sohail Ikram; Jan Kajstura; Annarosa Leri; John H Loughran; D Gregg Rokosh; Fumihiro Sanada; Mark S Slaughter; Naresh K Solankhi; Marcus F Stoddard; Stephen G Wagner; Garth M Beache; Piero Anversa
Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial.
Lancet 2011;378(9806):1847-57.
2011: Annarosa Leri; Piero Anversa; Toru Hosoda; Jan Kajstura; Marcello Rota
Identification of a coronary stem cell in the human heart.
Journal of molecular medicine (Berlin, Germany) 2011;89(10):947-59.
2011: Annarosa Leri; Jan Kajstura; Piero Anversa
Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biology.
Circulation research 2011;109(8):941-61.
2011: Piero Anversa; Jan Kajstura; Annarosa Leri; Joseph Loscalzo
Tissue-specific adult stem cells in the human lung.
Nature medicine 2011;17(9):1038-9.
2011: Daniela Cesselli; Federica D'Aurizio; Claudia Fiorini; Toru Hosoda; Jan Kajstura; Piero Anversa; Antonio P Beltrami; Carlo A Beltrami; Natascha Bergamin; Ugolino Livi; LUIGI MARCHIONNI; Patrizia Marcon; Laura Marino; Maura Pandolfi; Silvano Piazza; Elisa Puppato; Marcello Rota; Claudio Schneider; Sergio Signore; Barbara Toffoletto; Roberto Verardo; Annarosa Leri
Effects of age and heart failure on human cardiac stem cell function.
The American journal of pathology 2011;179(1):349-66.
2011: Domenico D'Amario; João Ferreira-Martins; Claudia Fiorini; Polina Goichberg; Toru Hosoda; Luigi Anastasia; Piero Anversa; Mauricio C Cabral-Da-Silva; Donato Cappetta; David D'Alessandro; Annarosa Leri; Robert Michler; Marco Piccoli; Marcello Rota; Fumihiro Sanada; Elisabeth Steadman; Hanqiao Zheng; Jan Kajstura
Insulin-like growth factor-1 receptor identifies a pool of human cardiac stem cells with superior therapeutic potential for myocardial regeneration.
Circulation research 2011;108(12):1467-81.
2011: Jan Kajstura; Annarosa Leri; Ronglih Liao; Xiaoli Liu; Joseph Loscalzo; Alex Matsuda; Barbara Ogórek; Mark A Perrella; Federico Quaini; Hussein Rayatzadeh; Carlos Rondon-Clavo; Marcello Rota; Fumihiro Sanada; Hanqiao Zheng; Christian Arranto; Silvana Bardelli; D'Amario Domenico; João Ferreira-Martins; Giovanna Giordano; Polina Goichberg; Kathleen J Haley; Sean R Hall; Toru Hosoda; Piero Anversa
Evidence for human lung stem cells.
The New England journal of medicine 2011;364(19):1795-806.
2011: Polina Goichberg; Yingnan Bai; Domenico D'Amario; João Ferreira-Martins; Claudia Fiorini; Hanqiao Zheng; Sergio Signore; Federica del Monte; Sergio Ottolenghi; David D'Alessandro; Robert Michler; Toru Hosoda; Piero Anversa; Jan Kajstura; Marcello Rota; Annarosa Leri
The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction.
Circulation research 2011;108(9):1071-83.
2011: Domenico D'Amario; Claudia Fiorini; Patricia M Campbell; Polina Goichberg; Fumihiro Sanada; Hanqiao Zheng; Toru Hosoda; Marcello Rota; John M Connell; Robert P Gallegos; Frederick G Welt; Michael M Givertz; Richard N Mitchell; Annarosa Leri; Jan Kajstura; Marc A Pfeffer; Piero Anversa
Functionally competent cardiac stem cells can be isolated from endomyocardial biopsies of patients with advanced cardiomyopathies.
Circulation research 2011;108(7):857-61.
2011: Toru Hosoda; Hanqiao Zheng; Mauricio Cabral-da-Silva; Fumihiro Sanada; Noriko Ide-Iwata; Barbara Ogórek; João Ferreira-Martins; Christian Arranto; Domenico D'Amario; Federica del Monte; Konrad Urbanek; David D'Alessandro; Robert Michler; Piero Anversa; Marcello Rota; Jan Kajstura; Annarosa Leri
Human cardiac stem cell differentiation is regulated by a mircrine mechanism.
Circulation 2011;123(12):1287-96.
2011: Annarosa Leri; Jan Kajstura; Piero Anversa
Mechanisms of myocardial regeneration.
Trends in cardiovascular medicine 2011;21(2):52-8.
2010: Jan Kajstura; Narasimman Gurusamy; Barbara Ogórek; Polina Goichberg; Carlos Clavo-Rondon; Toru Hosoda; D'Amario Domenico; Silvana Bardelli; Antonio P Beltrami; Daniela Cesselli; Rossana Bussani; Federica del Monte; Federico Quaini; Marcello Rota; Carlo Alberto Beltrami; Bruce A Buchholz; Annarosa Leri; Piero Anversa
Myocyte turnover in the aging human heart.
Circulation research 2010;107(11):1374-86.
2010: Hongyu Zhang; Xiongwen Chen; Erhe Gao; Scott M MacDonnell; Wei Wang; Mikhail Kolpakov; Hiroyuki Nakayama; Xiaoying Zhang; Naser Jaleel; David M Harris; Yingxin Li; Mingxin Tang; Remus M Berretta; Annarosa Leri; Jan Kajstura; Abdelkarim Sabri; Walter J Koch; Jeffery D Molkentin; Steven R Houser
Increasing cardiac contractility after myocardial infarction exacerbates cardiac injury and pump dysfunction.
Circulation research 2010;107(6):800-9.
2010: Konrad Urbanek; Mauricio Castro Cabral-da-Silva; Noriko Ide-Iwata; Silvia Maestroni; Francesca Delucchi; Hanqiao Zheng; João Ferreira-Martins; Barbara Ogórek; D'Amario Domenico; Michael Bauer; Gianpaolo Zerbini; Marcello Rota; Toru Hosoda; Ronglih Liao; Piero Anversa; Jan Kajstura; Annarosa Leri
Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.
Circulation research 2010;107(3):429-41.
2010: Jan Kajstura; Konrad Urbanek; Shira Perl; Toru Hosoda; Hanqiao Zheng; Barbara Ogórek; João Ferreira-Martins; Polina Goichberg; Carlos Rondon-Clavo; Fumihiro Sanada; D'Amario Domenico; Marcello Rota; Federica Del Monte; Donald Orlic; John Tisdale; Annarosa Leri; Piero Anversa
Cardiomyogenesis in the adult human heart.
Circulation research 2010;107(2):305-15.
2010: Xian-Liang Tang; Gregg Rokosh; Santosh K Sanganalmath; Fangping Yuan; Hiroshi Sato; Jianyao Mu; Shujing Dai; Chengxin Li; Ning Chen; Yong Peng; Buddhadeb Dawn; Greg Hunt; Annarosa Leri; Jan Kajstura; Sumit Tiwari; Gregg Shirk; Piero Anversa; Roberto Bolli
Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction.
Circulation 2010;121(2):293-305.
2010: Antonella De Angelis; Elena Piegari; Donato Cappetta; Laura Marino; Amelia Filippelli; Liberato Berrino; João Ferreira-Martins; Hanqiao Zheng; Toru Hosoda; Marcello Rota; Konrad Urbanek; Jan Kajstura; Annarosa Leri; Francesco Rossi; Piero Anversa
Anthracycline cardiomyopathy is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell function.
Circulation 2010;121(2):276-92.
2010: Toru Hosoda; Jan Kajstura; Annarosa Leri; Piero Anversa
Mechanisms of myocardial regeneration.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(1):13-7.
2009: David D'Alessandro; Jan Kajstura; Toru Hosoda; Alessandro Gatti; Ricardo Bello; Federico Mosna; Silvana Bardelli; Hanqiao Zheng; Domenico D'Amario; Maria Elena Padin-Iruegas; Adriana Bastos Carvalho; Marcello Rota; Michael O Zembala; David Stern; Ornella Rimoldi; Konrad Urbanek; Robert Michler; Annarosa Leri; Piero Anversa
Progenitor cells from the explanted heart generate immunocompatible myocardium within the transplanted donor heart.
Circulation research 2009;105(11):1128-40.
2009: João Ferreira-Martins; Carlos Rondon-Clavo; Derin Tugal; Justin A Korn; Roberto Rizzi; Maria Elena Padin-Iruegas; Sergio Ottolenghi; Antonella De Angelis; Konrad Urbanek; Noriko Ide-Iwata; D'Amario Domenico; Toru Hosoda; Annarosa Leri; Jan Kajstura; Piero Anversa; Marcello Rota
Spontaneous calcium oscillations regulate human cardiac progenitor cell growth.
Circulation research 2009;105(8):764-74.
2009: Toru Hosoda; D'Amario Domenico; Mauricio Castro Cabral-Da-Silva; Hanqiao Zheng; Maria Elena Padin-Iruegas; Barbara Ogorek; João Ferreira-Martins; Saori Yasuzawa-Amano; Katsuya Amano; Noriko Ide-Iwata; Wei Cheng; Marcello Rota; Konrad Urbanek; Jan Kajstura; Piero Anversa; Annarosa Leri
Clonality of mouse and human cardiomyogenesis in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(40):17169-74.
2009: Claudia Bearzi; Annarosa Leri; Francesco Lo Monaco; Marcello Rota; Arantxa Gonzalez; Toru Hosoda; Martino Pepe; Khaled Qanud; Caroline Ojaimi; Silvana Bardelli; D'Amario Domenico; David D'Alessandro; Robert Michler; Stefanie Dimmeler; Andreas M Zeiher; Konrad Urbanek; Thomas H Hintze; Jan Kajstura; Piero Anversa
Identification of a coronary vascular progenitor cell in the human heart.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(37):15885-90.
2009: M Elena Padin-Iruegas; Yu Misao; Michael E Davis; Vincent F M Segers; Grazia Esposito; Tomotake Tokunou; Konrad Urbanek; Toru Hosoda; Marcello Rota; Piero Anversa; Annarosa Leri; Richard T Lee; Jan Kajstura
Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction.
Circulation 2009;120(10):876-87.
2009: Xiaoli Liu; Tripurasundari Ramjiganesh; Yen-Hsu Chen; Su Wol Chung; Sean R Hall; Scott L Schissel; Robert F Padera; Ronglih Liao; Kate G Ackerman; Jan Kajstura; Annarosa Leri; Piero Anversa; Shaw-Fang Yet; Matthew D Layne; Mark A Perrella
Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice.
Circulation 2009;119(2):261-8.
2008: Alessandro Boni; Konrad Urbanek; Angelo Nascimbene; Toru Hosoda; Hanqiao Zheng; Francesca Delucchi; Katsuya Amano; Arantxa Gonzalez; Serena Vitale; Caroline Ojaimi; Roberto Rizzi; Roberto Bolli; Katherine E Yutzey; Marcello Rota; Jan Kajstura; Piero Anversa; Annarosa Leri
Notch1 regulates the fate of cardiac progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15529-34.
2008: Jan Kajstura; Konrad Urbanek; Marcello Rota; Claudia Bearzi; Toru Hosoda; Roberto Bolli; Piero Anversa; Annarosa Leri
Cardiac stem cells and myocardial disease.
Journal of molecular and cellular cardiology 2008;45(4):505-13.
2008: John Muraski; Kimberlee M Fischer; Weitao Wu; Travis Cottage; Pearl Quijada; Matt Mason; Shabana Din; Natalie Gude; Roberto Alvarez; Marcello Rota; Jan Kajstura; Zeping Wang; Erik M Schaefer; Xiongen Chen; Scott MacDonnel; Nancy Magnuson; Steven R Houser; Piero Anversa; Mark A Sussman
Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):13889-94.
2008: Marcello Rota; M Elena Padin-Iruegas; Yu Misao; Antonella De Angelis; Silvia Maestroni; João Ferreira-Martins; Emanuela Fiumana; Raffaella Rastaldo; Michael L Arcarese; Thomas S Mitchell; Alessandro Boni; Roberto Bolli; Konrad Urbanek; Toru Hosoda; Piero Anversa; Annarosa Leri; Jan Kajstura
Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function.
Circulation research 2008;103(1):107-16.
2008: Sailay Siddiqi; Natalie Gude; Toru Hosoda; John Muraski; Marta Rubio; Gregory Emmanuel; Jenna Fransioli; Serena Vitale; Carola Parolin; D'Amario Domenico; Erik M Schaefer; Jan Kajstura; Annarosa Leri; Piero Anversa; Mark A Sussman
Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge.
Circulation research 2008;103(1):89-97.
2008: Jan Kajstura; Toru Hosoda; Claudia Bearzi; Marcello Rota; Silvia Maestroni; Konrad Urbanek; Annarosa Leri; Piero Anversa
The human heart: a self-renewing organ.
Clinical and translational science 2008;1(1):80-6.
2008: Arantxa Gonzalez; Marcello Rota; Daria Nurzynska; Yu Misao; Jochen Tillmanns; Caroline Ojaimi; M Elena Padin-Iruegas; Patrick Müller; Grazia Esposito; Claudia Bearzi; Serena Vitale; Buddhadeb Dawn; Santosh K Sanganalmath; Mathue Baker; Thomas H Hintze; Roberto Bolli; Konrad Urbanek; Toru Hosoda; Piero Anversa; Jan Kajstura; Annarosa Leri
Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan.
Circulation research 2008;102(5):597-606.
2008: Annarosa Leri; Jan Kajstura; Piero Anversa; William H Frishman
Myocardial regeneration and stem cell repair.
Current problems in cardiology 2008;33(3):91-153.
2008: Jun Ren; Jinhong Duan; D Paul Thomas; Xiaoping Yang; Nair Sreejayan; James R Sowers; Annarosa Leri; Jan Kajstura; Feng Gao; Piero Anversa
IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;294(3):R793-802.
2008: Jochen Tillmanns; Marcello Rota; Toru Hosoda; Yu Misao; Grazia Esposito; Arantxa Gonzalez; Serena Vitale; Carola Parolin; Saori Yasuzawa-Amano; John Muraski; Antonella De Angelis; Nicole Lecapitaine; robert siggins; Maria Loredo; Claudia Bearzi; Roberto Bolli; Konrad Urbanek; Annarosa Leri; Jan Kajstura; Piero Anversa
Formation of large coronary arteries by cardiac progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1668-73.
2007: John Muraski; Marcello Rota; Yu Misao; Jenna Fransioli; Travis Cottage; Natalie Gude; Grazia Esposito; Francesca Delucchi; Michael Arcarese; Roberto Alvarez; Sailay Siddiqi; Gregory N Emmanuel; Weitao Wu; Kimberlee Fischer; Joshua Martindale; Christopher C Glembotski; Annarosa Leri; Jan Kajstura; Nancy Magnuson; Anton Berns; Remus M Beretta; Steven R Houser; Erik M Schaefer; Piero Anversa; Mark A Sussman
Pim-1 regulates cardiomyocyte survival downstream of Akt.
Nature medicine 2007;13(12):1467-75.
2007: Marcello Rota; Jan Kajstura; Toru Hosoda; Claudia Bearzi; Serena Vitale; Grazia Esposito; Grazia Iaffaldano; Maria Elena Padin-Iruegas; Arantxa Gonzalez; Roberto Rizzi; Narissa Small; John Muraski; Roberto Alvarez; Xiongwen Chen; Konrad Urbanek; Roberto Bolli; Steven R Houser; Annarosa Leri; Mark A Sussman; Piero Anversa
Bone marrow cells adopt the cardiomyogenic fate in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(45):17783-8.
2007: Claudia Bearzi; Marcello Rota; Toru Hosoda; Jochen Tillmanns; Angelo Nascimbene; Antonella De Angelis; Saori Yasuzawa-Amano; Irina Trofimova; robert siggins; Nicole Lecapitaine; Stefano Cascapera; Antonio P Beltrami; David D'Alessandro; Elias Zias; Federico Quaini; Konrad Urbanek; Robert Michler; Roberto Bolli; Jan Kajstura; Annarosa Leri; Piero Anversa
Human cardiac stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):14068-73.
2007: Marcello Rota; Toru Hosoda; Antonella De Angelis; Michael L Arcarese; Grazia Esposito; Roberto Rizzi; Jochen Tillmanns; Derin Tugal; Ezio Musso; Ornella Rimoldi; Claudia Bearzi; Konrad Urbanek; Piero Anversa; Annarosa Leri; Jan Kajstura
The young mouse heart is composed of myocytes heterogeneous in age and function.
Circulation research 2007;101(4):387-99.
2007: Xiongwen Chen; Rachel M Wilson; Hajime Kubo; Remus M Berretta; David M Harris; Xiaoying Zhang; Naser Jaleel; Scott M MacDonnell; Claudia Bearzi; Jochen Tillmanns; Irina Trofimova; Toru Hosoda; Federico Mosna; Leanne Cribbs; Annarosa Leri; Jan Kajstura; Piero Anversa; Steven R Houser
Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties.
Circulation research 2007;100(4):536-44.
2007: Piero Anversa; Annarosa Leri; Marcello Rota; Toru Hosoda; Claudia Bearzi; Konrad Urbanek; Jan Kajstura; Roberto Bolli
Concise review: stem cells, myocardial regeneration, and methodological artifacts.
Stem cells (Dayton, Ohio) 2007;25(3):589-601.
2007: Qun Li; Shan Wu; Shi-Yan Li; Faye L Lopez; Min Du; Jan Kajstura; Piero Anversa; Jun Ren
Cardiac-specific overexpression of insulin-like growth factor 1 attenuates aging-associated cardiac diastolic contractile dysfunction and protein damage.
American journal of physiology. Heart and circulatory physiology 2007;292(3):H1398-403.
2007: Piero Anversa; Jan Kajstura; Annarosa Leri
If I can stop one heart from breaking.
Circulation 2007;115(7):829-32.
2006: Jan Kajstura; Marcello Rota; Konrad Urbanek; Toru Hosoda; Claudia Bearzi; Piero Anversa; Roberto Bolli; Annarosa Leri
The telomere-telomerase axis and the heart.
Antioxidants & redox signaling 2006;8(11-12):2125-41.
2006: Natalie Gude; John Muraski; Marta Rubio; Jan Kajstura; Erik M Schaefer; Piero Anversa; Mark A Sussman
Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population.
Circulation research 2006;99(4):381-8.
2006: Yasuyuki Tsujita; John Muraski; Isao Shiraishi; Takahiro Kato; Jan Kajstura; Piero Anversa; Mark A Sussman
Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):11946-51.
2006: Annarosa Leri; Jan Kajstura; Piero Anversa
[Bone marrow cells and cardiac repair].
Arquivos brasileiros de cardiologia 2006;87(2):71-2.
2006: Marcello Rota; Nicole LeCapitaine; Toru Hosoda; Alessandro Boni; Antonella De Angelis; Maria Elena Padin-Iruegas; Grazia Esposito; Serena Vitale; Konrad Urbanek; Claudia Casarsa; Marco Giorgio; Thomas F Lüscher; Pier Giuseppe Pelicci; Piero Anversa; Annarosa Leri; Jan Kajstura
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene.
Circulation research 2006;99(1):42-52.
2006: Konrad Urbanek; Daniela Cesselli; Marcello Rota; Angelo Nascimbene; Antonella De Angelis; Toru Hosoda; Claudia Bearzi; Alessandro Boni; Roberto Bolli; Jan Kajstura; Piero Anversa; Annarosa Leri
Stem cell niches in the adult mouse heart.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9226-31.
2006: Piero Anversa; Annarosa Leri; Jan Kajstura
Cardiac regeneration.
Journal of the American College of Cardiology 2006;47(9):1769-76.
2006: Nazareno Paolocci; Barbara Tavazzi; Roberto Biondi; Yehezkiel A Gluzband; Angela Maria Amorini; Carlo G Tocchetti; Mehrdad Hejazi; Patrizio Caturegli; Jan Kajstura; Giuseppe Lazzarino; David A Kass
Metalloproteinase inhibitor counters high-energy phosphate depletion and AMP deaminase activity enhancing ventricular diastolic compliance in subacute heart failure.
The Journal of pharmacology and experimental therapeutics 2006;317(2):506-13.
2006: Buddhadeb Dawn; Yiru Guo; Arash Rezazadeh; Yiming Huang; Adam B Stein; Greg Hunt; Sumit Tiwari; Jai Varma; Yan Gu; Sumanth D Prabhu; Jan Kajstura; Piero Anversa; Suzanne Ildstad; Roberto Bolli
Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function.
Circulation research 2006;98(8):1098-105.
2006: Jan Kajstura; Roberto Bolli; Edmund H Sonnenblick; Piero Anversa; Annarosa Leri
Cause of death: suicide.
Journal of molecular and cellular cardiology 2006;40(4):425-37.
2006: Piero Anversa; Jan Kajstura; Annarosa Leri; Roberto Bolli
Life and death of cardiac stem cells: a paradigm shift in cardiac biology.
Circulation 2006;113(11):1451-63.
2006: Annarosa Leri; Toru Hosoda; Jan Kajstura; Piero Anversa
Heart failure and regenerative cardiology.
Regenerative medicine 2006;1(2):153-9.
2006: Jan Kajstura; Annarosa Leri; Roberto Bolli; Piero Anversa
Endothelial progenitor cells: neovascularization or more?
Journal of molecular and cellular cardiology 2006;40(1):1-8.
2005: Piero Anversa; Marcello Rota; Konrad Urbanek; Toru Hosoda; Edmund H Sonnenblick; Annarosa Leri; Jan Kajstura; Roberto Bolli
Myocardial aging--a stem cell problem.
Basic research in cardiology 2005;100(6):482-93.
2005: Federica Limana; Antonia Germani; Antonella Zacheo; Jan Kajstura; Anna Di Carlo; Giovanna Borsellino; Omar Leoni; Roberta Palumbo; Luca Battistini; Raffaella Rastaldo; Susanne Müller; Giulio Pompilio; Piero Anversa; Marco E Bianchi; Maurizio C Capogrossi
Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation.
Circulation research 2005;97(8):e73-83.
2005: Annarosa Leri; Jan Kajstura; Piero Anversa
Cardiac stem cells and mechanisms of myocardial regeneration.
Physiological reviews 2005;85(4):1373-416.
2005: Konrad Urbanek; Marcello Rota; Stefano Cascapera; Claudia Bearzi; Angelo Nascimbene; Antonella De Angelis; Toru Hosoda; Stefano Chimenti; Mathue Baker; Federica Limana; Daria Nurzynska; Daniele Torella; Francesco Rotatori; Raffaella Rastaldo; Ezio Musso; Federico Quaini; Annarosa Leri; Jan Kajstura; Piero Anversa
Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival.
Circulation research 2005;97(7):663-73.
2005: Annarosa Leri; Jan Kajstura
Endothelial progenitor cells: unexpected disclosures.
Circulation research 2005;97(4):299-301.
2005: Axel Linke; Patrick Müller; Daria Nurzynska; Claudia Casarsa; Daniele Torella; Angelo Nascimbene; Clotilde Castaldo; Stefano Cascapera; Michael Böhm; Federico Quaini; Konrad Urbanek; Annarosa Leri; Thomas H Hintze; Jan Kajstura; Piero Anversa
Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(25):8966-71.
2005: Konrad Urbanek; Daniele Torella; Farooq Sheikh; Antonella De Angelis; Daria Nurzynska; Furio Silvestri; Carlo Alberto Beltrami; Rossana Bussani; Antonio P Beltrami; Federico Quaini; Roberto Bolli; Annarosa Leri; Jan Kajstura; Piero Anversa
Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(24):8692-7.
2005: Annarosa Leri; Jan Kajstura; Piero Anversa
Identity deception: not a crime for a stem cell.
Physiology (Bethesda, Md.) 2005;20():162-8.
2005: Annarosa Leri; Jan Kajstura; Piero Anversa
Regenerating the myocardium: a reality today.
The Canadian journal of cardiology 2005;21(4):361-2.
2005: Buddhadeb Dawn; Adam B Stein; Konrad Urbanek; Marcello Rota; Brian Whang; Raffaella Rastaldo; Daniele Torella; Xian-Liang Tang; Arash Rezazadeh; Jan Kajstura; Annarosa Leri; Greg Hunt; Jai Varma; Sumanth D Prabhu; Piero Anversa; Roberto Bolli
Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(10):3766-71.
2005: Jan Kajstura; Marcello Rota; Brian Whang; Stefano Cascapera; Toru Hosoda; Claudia Bearzi; Daria Nurzynska; Hideko Kasahara; Elias Zias; Massimiliano Bonafé; Bernardo Nadal-Ginard; Daniele Torella; Angelo Nascimbene; Federico Quaini; Konrad Urbanek; Annarosa Leri; Piero Anversa
Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion.
Circulation research 2005;96(1):127-37.
2005: Bernardo Nadal-Ginard; Piero Anversa; Jan Kajstura; Annarosa Leri
Cardiac stem cells and myocardial regeneration.
Novartis Foundation symposium 2005;265():142-54; discussion 155-7, 204-11.
2004: Piero Anversa; Jan Kajstura; Annarosa Leri
Circulating progenitor cells: search for an identity.
Circulation 2004;110(20):3158-60.
2004: Isao Shiraishi; Jaime Melendez; Youngkeun Ahn; Maryanne Skavdahl; Elizabeth Murphy; Sara Welch; Erik M Schaefer; Kenneth Walsh; Anthony Rosenzweig; Daniele Torella; Daria Nurzynska; Jan Kajstura; Annarosa Leri; Piero Anversa; Mark A Sussman
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes.
Circulation research 2004;94(7):884-91.
2004: Robert Lanza; Malcolm A S Moore; Teruhiko Wakayama; Anthony C F Perry; Jae-Hung Shieh; Jan Hendrikx; Annarosa Leri; Stefano Chimenti; Alyssa Monsen; Daria Nurzynska; Michael D West; Jan Kajstura; Piero Anversa
Regeneration of the infarcted heart with stem cells derived by nuclear transplantation.
Circulation research 2004;94(6):820-7.
2004: Daniele Torella; Marcello Rota; Daria Nurzynska; Ezio Musso; Alyssa Monsen; Isao Shiraishi; Elias Zias; Kenneth Walsh; Anthony Rosenzweig; Mark A Sussman; Konrad Urbanek; Bernardo Nadal-Ginard; Jan Kajstura; Piero Anversa; Annarosa Leri
Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.
Circulation research 2004;94(4):514-24.
2004: Annarosa Leri; Jan Kajstura; Bernardo Nadal-Ginard; Piero Anversa
Some like it plastic.
Circulation research 2004;94(2):132-4.
2004: Jan Kajstura; Annarosa Leri; Clotilde Castaldo; Bernardo Nadal-Ginard; Piero Anversa
Myocyte growth in the failing heart.
The Surgical clinics of North America 2004;84(1):161-77.
2003: Cristina Chimenti; Jan Kajstura; Daniele Torella; Konrad Urbanek; Hubert Heleniak; Claudia Colussi; Franca Di Meglio; Bernardo Nadal-Ginard; Andrea Frustaci; Annarosa Leri; Attilio Maseri; Piero Anversa
Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure.
Circulation research 2003;93(7):604-13.
2003: Heiner Post; Jan Kajstura; Biao Lei; William C Sessa; Barry Byrne; Piero Anversa; Thomas H Hintze; Fabio A Recchia
Adeno-associated virus mediated gene delivery into coronary microvessels of chronically instrumented dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(4):1688-94.
2003: Antonio P Beltrami; Laura Barlucchi; Daniele Torella; Mathue Baker; Federica Limana; Stefano Chimenti; Hideko Kasahara; Marcello Rota; Ezio Musso; Konrad Urbanek; Annarosa Leri; Jan Kajstura; Bernardo Nadal-Ginard; Piero Anversa
Adult cardiac stem cells are multipotent and support myocardial regeneration.
Cell 2003;114(6):763-76.
2003: Konrad Urbanek; Federico Quaini; Giordano Tasca; Daniele Torella; Clotilde Castaldo; Bernardo Nadal-Ginard; Annarosa Leri; Jan Kajstura; Eugenio Quaini; Piero Anversa
Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10440-5.
2003: Annarosa Leri; Jan Kajstura
Myocardial damage and repair.
Journal of molecular and cellular cardiology 2003;35(6):595-7.
2003: Bernardo Nadal-Ginard; Jan Kajstura; Piero Anversa; Annarosa Leri
A matter of life and death: cardiac myocyte apoptosis and regeneration.
The Journal of clinical investigation 2003;111(10):1457-9.
2003: Laura Calvillo; Roberto Latini; Jan Kajstura; Annarosa Leri; Piero Anversa; Pietro Ghezzi; Monica Salio; Anthony Cerami; Michael Brines
Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4802-6.
2003: Piero Anversa; Jan Kajstura; Bernardo Nadal-Ginard; Annarosa Leri
Primitive cells and tissue regeneration.
Circulation research 2003;92(6):579-82.
2003: Bernardo Nadal-Ginard; Jan Kajstura; Annarosa Leri; Piero Anversa
Myocyte death, growth, and regeneration in cardiac hypertrophy and failure.
Circulation research 2003;92(2):139-50.
2003: Annarosa Leri; Sonia Franco; Antonella Zacheo; Laura Barlucchi; Stefano Chimenti; Federica Limana; Bernardo Nadal-Ginard; Jan Kajstura; Piero Anversa; María A Blasco
Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation.
The EMBO journal 2003;22(1):131-9.
2003: Donald Orlic; Jan Kajstura; Stefano Chimenti; David M Bodine; Annarosa Leri; Piero Anversa
Bone marrow stem cells regenerate infarcted myocardium.
Pediatric transplantation 2003;7 Suppl 3():86-8.
2002: Annarosa Leri; Jan Kajstura; Piero Anversa
Myocyte proliferation and ventricular remodeling.
Journal of cardiac failure 2002;8(6 Suppl):S518-25.
2002: Federica Limana; Konrad Urbanek; Stefano Chimenti; Federico Quaini; Annarosa Leri; Jan Kajstura; Bernardo Nadal-Ginard; Seigo Izumo; Piero Anversa
bcl-2 overexpression promotes myocyte proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6257-62.
2002: Sara Welch; David M Plank; Sandra Witt; Betty J Glascock; Erik M Schaefer; Stefano Chimenti; Anna Maria Andreoli; Federica Limana; Annarosa Leri; Jan Kajstura; Piero Anversa; Mark A Sussman
Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice.
Circulation research 2002;90(6):641-8.
2002: Piero Anversa; Annarosa Leri; Jan Kajstura; Bernardo Nadal-Ginard
Myocyte growth and cardiac repair.
Journal of molecular and cellular cardiology 2002;34(2):91-105.
2002: Federico Quaini; Konrad Urbanek; Antonio P Beltrami; Nicoletta Finato; Carlo Alberto Beltrami; Bernardo Nadal-Ginard; Jan Kajstura; Annarosa Leri; Piero Anversa
Chimerism of the transplanted heart.
The New England journal of medicine 2002;346(1):5-15.
2001: F Fiordaliso; Annarosa Leri; Daniela Cesselli; Federica Limana; Bijan Safai; Bernardo Nadal-Ginard; Piero Anversa; Jan Kajstura
Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death.
Diabetes 2001;50(10):2363-75.
2001: Annarosa Leri; Federico Quaini; Jan Kajstura; Piero Anversa
Myocyte death and myocyte regeneration in the failing human heart.
Italian heart journal : official journal of the Italian Federation of Cardiology 2001;2 Suppl 3():12S-14S.
2001: Donald Orlic; Jan Kajstura; Stefano Chimenti; Federica Limana; I Jakoniuk; Federico Quaini; Bernardo Nadal-Ginard; David M Bodine; Annarosa Leri; Piero Anversa
Mobilized bone marrow cells repair the infarcted heart, improving function and survival.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10344-9.
2001: Daniela Cesselli; I Jakoniuk; Laura Barlucchi; Antonio P Beltrami; Thomas H Hintze; Bernardo Nadal-Ginard; Jan Kajstura; Annarosa Leri; Piero Anversa
Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy.
Circulation research 2001;89(3):279-86.
2001: Annarosa Leri; Laura Barlucchi; Federica Limana; A Deptala; Zbigniew Darzynkiewicz; Thomas H Hintze; Jan Kajstura; Bernardo Nadal-Ginard; Piero Anversa
Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8626-31.
2001: Antonio P Beltrami; Konrad Urbanek; Jan Kajstura; SM Yan; Nicoletta Finato; R Bussani; Bernardo Nadal-Ginard; F Silvestri; Annarosa Leri; Carlo Alberto Beltrami; Piero Anversa
Evidence that human cardiac myocytes divide after myocardial infarction.
The New England journal of medicine 2001;344(23):1750-7.
2001: Donald Orlic; Jan Kajstura; Stefano Chimenti; David M Bodine; Annarosa Leri; Piero Anversa
Transplanted adult bone marrow cells repair myocardial infarcts in mice.
Annals of the New York Academy of Sciences 2001;938():221-9; discussion 229-30.
2001: Jan Kajstura; F Fiordaliso; A M Andreoli; Bing Li; Stefano Chimenti; Marvin S Medow; Federica Limana; Bernardo Nadal-Ginard; Annarosa Leri; Piero Anversa
IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress.
Diabetes 2001;50(6):1414-24.
2001: D Camper-Kirby; Sara Welch; A Walker; Isao Shiraishi; K D Setchell; Erik M Schaefer; Jan Kajstura; Piero Anversa; Mark A Sussman
Myocardial Akt activation and gender: increased nuclear activity in females versus males.
Circulation research 2001;88(10):1020-7.
2001: Donald Orlic; Jan Kajstura; Stefano Chimenti; I Jakoniuk; Stacie M Anderson; B Li; J Pickel; R McKay; Bernardo Nadal-Ginard; David M Bodine; Annarosa Leri; Piero Anversa
Bone marrow cells regenerate infarcted myocardium.
Nature 2001;410(6829):701-5.
2001: Laura Barlucchi; Annarosa Leri; David Dostal; F Fiordaliso; H Tada; Thomas H Hintze; Jan Kajstura; Bernardo Nadal-Ginard; Piero Anversa
Canine ventricular myocytes possess a renin-angiotensin system that is upregulated with heart failure.
Circulation research 2001;88(3):298-304.
2000: Andrea Frustaci; Jan Kajstura; Cristina Chimenti; I Jakoniuk; Annarosa Leri; A Maseri; Bernardo Nadal-Ginard; Piero Anversa
Myocardial cell death in human diabetes.
Circulation research 2000;87(12):1123-32.
2000: Annarosa Leri; F Fiordaliso; M Setoguchi; Federica Limana; Nanette H Bishopric; Jan Kajstura; Keith A Webster; Piero Anversa
Inhibition of p53 function prevents renin-angiotensin system activation and stretch-mediated myocyte apoptosis.
The American journal of pathology 2000;157(3):843-57.
2000: Annarosa Leri; Y Liu; Bing Li; F Fiordaliso; A Malhotra; Roberto Latini; Jan Kajstura; Piero Anversa
Up-regulation of AT(1) and AT(2) receptors in postinfarcted hypertrophied myocytes and stretch-mediated apoptotic cell death.
The American journal of pathology 2000;156(5):1663-72.
2000: F Fiordaliso; Bing Li; Roberto Latini; Edmund H Sonnenblick; Piero Anversa; Annarosa Leri; Jan Kajstura
Myocyte death in streptozotocin-induced diabetes in rats in angiotensin II- dependent.
Laboratory investigation; a journal of technical methods and pathology 2000;80(4):513-27.
2000: Annarosa Leri; Jan Kajstura; B Li; Edmund H Sonnenblick; C A Beltrami; Piero Anversa; W H Frishman
Cardiomyocyte aging is gender-dependent: the local IGF-1-IGF-1R system.
Heart disease (Hagerstown, Md.) 2000;2(2):108-15.
2000: Annarosa Leri; A Malhotra; C C Liew; Jan Kajstura; Piero Anversa
Telomerase activity in rat cardiac myocytes is age and gender dependent.
Journal of molecular and cellular cardiology 2000;32(3):385-90.
2000: Jan Kajstura; Barbara Pertoldi; Annarosa Leri; Carlo Alberto Beltrami; A Deptala; Zbigniew Darzynkiewicz; Piero Anversa
Telomere shortening is an in vivo marker of myocyte replication and aging.
The American journal of pathology 2000;156(3):813-9.
1999: M Setoguchi; Annarosa Leri; S Wang; Y Liu; A De Luca; Antonio Giordano; T H Hintze; Jan Kajstura; Piero Anversa
Activation of cyclins and cyclin-dependent kinases, DNA synthesis, and myocyte mitotic division in pacing-induced heart failure in dogs.
Laboratory investigation; a journal of technical methods and pathology 1999;79(12):1545-58.
1999: S Guerra; Annarosa Leri; X Wang; Nicoletta Finato; C Di Loreto; Carlo Alberto Beltrami; Jan Kajstura; Piero Anversa
Myocyte death in the failing human heart is gender dependent.
Circulation research 1999;85(9):856-66.
1999: Bing Li; M Setoguchi; X Wang; A M Andreoli; Annarosa Leri; A Malhotra; Jan Kajstura; Piero Anversa
Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart.
Circulation research 1999;84(9):1007-19.
1999: Annarosa Leri; Y Liu; X Wang; Jan Kajstura; A Malhotra; LG Meggs; Piero Anversa
Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice.
Circulation research 1999;84(7):752-62.
1999: Andrea Frustaci; Cristina Chimenti; M Setoguchi; S Guerra; S Corsello; F Crea; Annarosa Leri; Jan Kajstura; Piero Anversa; A Maseri
Cell death in acromegalic cardiomyopathy.
Circulation 1999;99(11):1426-34.
1999: Annarosa Leri; Y Liu; P P Claudio; Jan Kajstura; X Wang; S Wang; P Kang; A Malhotra; Piero Anversa
Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis.
The American journal of pathology 1999;154(2):567-80.
1998: Jan Kajstura; Y Liu; A Baldini; B Li; Giorgio Olivetti; Annarosa Leri; Piero Anversa
Coronary artery constriction in rats: necrotic and apoptotic myocyte death.
The American journal of cardiology 1998;82(5A):30K-41K.
1998: Jan Kajstura; Annarosa Leri; Nicoletta Finato; C Di Loreto; Carlo Alberto Beltrami; Piero Anversa
Myocyte proliferation in end-stage cardiac failure in humans.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8801-5.
1998: Piero Anversa; Jan Kajstura
Ventricular myocytes are not terminally differentiated in the adult mammalian heart.
Circulation research 1998;83(1):1-14.
1998: Piero Anversa; Annarosa Leri; C A Beltrami; S Guerra; Jan Kajstura
Myocyte death and growth in the failing heart.
Laboratory investigation; a journal of technical methods and pathology 1998;78(7):767-86.
1998: Y Liu; Annarosa Leri; Bing Li; X Wang; W Cheng; Jan Kajstura; Piero Anversa
Angiotensin II stimulation in vitro induces hypertrophy of normal and postinfarcted ventricular myocytes.
Circulation research 1998;82(11):1145-59.
1998: Annarosa Leri; P P Claudio; Q Li; X Wang; K Reiss; S Wang; A Malhotra; Jan Kajstura; Piero Anversa
Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell.
The Journal of clinical investigation 1998;101(7):1326-42.
1998: JA Nitahara; W Cheng; Y Liu; Bing Li; Annarosa Leri; P Li; D Mogul; Steven Gambert; Jan Kajstura; Piero Anversa
Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats.
Journal of molecular and cellular cardiology 1998;30(3):519-35.
1998: Annarosa Leri; Y Liu; A Malhotra; Q Li; Peter Stiegler; P P Claudio; A Giordano; Jan Kajstura; Thomas H Hintze; Piero Anversa
Pacing-induced heart failure in dogs enhances the expression of p53 and p53-dependent genes in ventricular myocytes.
Circulation 1998;97(2):194-203.
1998: Piero Anversa; W Cheng; Y Liu; Annarosa Leri; G Redaelli; Jan Kajstura
Apoptosis and myocardial infarction.
Basic research in cardiology 1998;93 Suppl 3():8-12.
1997: Bing Li; Q Li; X Wang; K P Jana; G Redaelli; Jan Kajstura; Piero Anversa
Coronary constriction impairs cardiac function and induces myocardial damage and ventricular remodeling in mice.
The American journal of physiology 1997;273(5 Pt 2):H2508-19.
1997: Q Li; B Li; X Wang; Annarosa Leri; K P Jana; Y Liu; Jan Kajstura; R Baserga; Piero Anversa
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy.
The Journal of clinical investigation 1997;100(8):1991-9.
1997: Carlo Alberto Beltrami; Carla Di Loreto; Nicoletta Finato; M Rocco; Daria Artico; E Cigola; Steven Gambert; Giorgio Olivetti; Jan Kajstura; Piero Anversa
Proliferating cell nuclear antigen (PCNA), DNA synthesis and mitosis in myocytes following cardiac transplantation in man.
Journal of molecular and cellular cardiology 1997;29(10):2789-802.
1997: P Pierzchalski; K Reiss; W Cheng; corrado cirielli; Jan Kajstura; JA Nitahara; M Rizk; Maurizio C Capogrossi; Piero Anversa
p53 Induces myocyte apoptosis via the activation of the renin-angiotensin system.
Experimental cell research 1997;234(1):57-65.
1997: Giorgio Olivetti; R Abbi; Federico Quaini; Jan Kajstura; W Cheng; JA Nitahara; Eugenio Quaini; C Di Loreto; Carlo Alberto Beltrami; S Krajewski; J C Reed; Piero Anversa
Apoptosis in the failing human heart.
The New England journal of medicine 1997;336(16):1131-41.
1997: E Cigola; Jan Kajstura; Bing Li; LG Meggs; Piero Anversa
Angiotensin II activates programmed myocyte cell death in vitro.
Experimental cell research 1997;231(2):363-71.
1997: Jan Kajstura; E Cigola; A Malhotra; P Li; W Cheng; LG Meggs; Piero Anversa
Angiotensin II induces apoptosis of adult ventricular myocytes in vitro.
Journal of molecular and cellular cardiology 1997;29(3):859-70.
1997: Piero Anversa; Giorgio Olivetti; Annarosa Leri; Y Liu; Jan Kajstura
Myocyte cell death and ventricular remodeling.
Current opinion in nephrology and hypertension 1997;6(2):169-76.
1996: Piero Anversa; Jan Kajstura; W Cheng; K Reiss; E Cigola; Giorgio Olivetti
Insulin-like growth factor-1 and myocyte growth: the danger of a dogma part II. Induced myocardial growth: pathologic hypertrophy.
Cardiovascular research 1996;32(3):484-95.
1996: Jan Kajstura; W Cheng; R Sarangarajan; P Li; Bing Li; J A Nitahara; S Chapnick; K Reiss; Giorgio Olivetti; Piero Anversa
Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats.
The American journal of physiology 1996;271(3 Pt 2):H1215-28.
1996: K Reiss; W Cheng; A Ferber; Jan Kajstura; P Li; B Li; G Olivetti; C J Homcy; Renato Baserga; Piero Anversa
Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8630-5.
1996: W Cheng; Jan Kajstura; J A Nitahara; Bing Li; K Reiss; Y Liu; W A Clark; S Krajewski; J C Reed; Giorgio Olivetti; Piero Anversa
Programmed myocyte cell death affects the viable myocardium after infarction in rats.
Experimental cell research 1996;226(2):316-27.
1996: Piero Anversa; Jan Kajstura; W Cheng; K Reiss; E Cigola; Giorgio Olivetti
Insulin-like growth factor-1 and myocyte growth: the danger of a dogma. Part I. Postnatal myocardial development: normal growth.
Cardiovascular research 1996;32(2):219-25.
1996: K Reiss; W Cheng; A Giorando; A De Luca; Bing Li; Jan Kajstura; Piero Anversa
Myocardial infarction is coupled with activation of cyclins and cyclin-dependent kinases in myocytes.
Experimental cell research 1996;225(1):44-54.
1996: W Cheng; K Reiss; P Li; M J Chun; Jan Kajstura; Giorgio Olivetti; Piero Anversa
Aging does not affect the activation of the myocyte insulin-like growth factor-1 autocrine system after infarction and ventricular failure in Fischer 344 rats.
Circulation research 1996;78(4):536-46.
1996: Jan Kajstura; W Cheng; K Reiss; W A Clark; Edmund H Sonnenblick; S Krajewski; J C Reed; Giorgio Olivetti; Piero Anversa
Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.
Laboratory investigation; a journal of technical methods and pathology 1996;74(1):86-107.
1995: Piero Anversa; Jan Kajstura; W Cheng; Bing Li; Edmund H Sonnenblick; P Li
Pathogenetic mechanisms of ischemic cardiomyopathy.
Cardiologia (Rome, Italy) 1995;40(12 Suppl 1):71-3.
1995: Piero Anversa; S Di Somma; G Bianchi; Bing Li; Jan Kajstura; W Cheng; Edmund H Sonnenblick; Giorgio Olivetti; P Li
Cellular mechanisms of cardiac failure in the infarcted heart.
Cardiologia (Rome, Italy) 1995;40(12):909-20.
1995: Piero Anversa; K Reiss; Jan Kajstura; W Cheng; P Li; Edmund H Sonnenblick; Giorgio Olivetti
Myocardial infarction and the myocyte IGF1 autocrine system.
European heart journal 1995;16 Suppl N():37-45.
1995: Y Liu; E Cigola; W Cheng; Jan Kajstura; Giorgio Olivetti; T H Hintze; Piero Anversa
Myocyte nuclear mitotic division and programmed myocyte cell death characterize the cardiac myopathy induced by rapid ventricular pacing in dogs.
Laboratory investigation; a journal of technical methods and pathology 1995;73(6):771-87.
1995: W Cheng; Bing Li; Jan Kajstura; P Li; M S Wolin; E H Sonnenblick; T H Hintze; Giorgio Olivetti; Piero Anversa
Stretch-induced programmed myocyte cell death.
The Journal of clinical investigation 1995;96(5):2247-59.
1995: Xiaoping Zhang; David E Dostal; K Reiss; W Cheng; Jan Kajstura; P Li; H Huang; Edmund H Sonnenblick; LG Meggs; Kenneth M Baker
Identification and activation of autocrine renin-angiotensin system in adult ventricular myocytes.
The American journal of physiology 1995;269(5 Pt 2):H1791-802.
1995: Jan Kajstura; Xiaoping Zhang; Y Liu; E Szoke; W Cheng; Giorgio Olivetti; T H Hintze; Piero Anversa
The cellular basis of pacing-induced dilated cardiomyopathy. Myocyte cell loss and myocyte cellular reactive hypertrophy.
Circulation 1995;92(8):2306-17.
1995: K Reiss; W Cheng; Jan Kajstura; Edmund H Sonnenblick; LG Meggs; Piero Anversa
Fibroblast proliferation during myocardial development in rats is regulated by IGF-1 receptors.
The American journal of physiology 1995;269(3 Pt 2):H943-51.
1995: Jan Kajstura; M Mansukhani; W Cheng; K Reiss; S Krajewski; J C Reed; Federico Quaini; Edmund H Sonnenblick; Piero Anversa
Programmed cell death and expression of the protooncogene bcl-2 in myocytes during postnatal maturation of the heart.
Experimental cell research 1995;219(1):110-21.
1995: W Cheng; K Reiss; Jan Kajstura; K Kowal; Federico Quaini; Piero Anversa
Down-regulation of the IGF-1 system parallels the attenuation in the proliferative capacity of rat ventricular myocytes during postnatal development.
Laboratory investigation; a journal of technical methods and pathology 1995;72(6):646-55.
1995: Piero Anversa; X Zhang; P Li; Giorgio Olivetti; W Cheng; K Reiss; Edmund H Sonnenblick; Jan Kajstura
Ventricular remodeling in global ischemia.
Cardioscience 1995;6(2):89-100.
1995: Piero Anversa; Jan Kajstura; K Reiss; Federico Quaini; A Baldini; Giorgio Olivetti; Edmund H Sonnenblick
Ischemic cardiomyopathy: myocyte cell loss, myocyte cellular hypertrophy, and myocyte cellular hyperplasia.
Annals of the New York Academy of Sciences 1995;752():47-64.
1994: Jan Kajstura; W Cheng; K Reiss; Piero Anversa
The IGF-1-IGF-1 receptor system modulates myocyte proliferation but not myocyte cellular hypertrophy in vitro.
Experimental cell research 1994;215(2):273-83.
1994: K Reiss; Jan Kajstura; Xiaoping Zhang; P Li; E Szoke; Giorgio Olivetti; Piero Anversa
Acute myocardial infarction leads to upregulation of the IGF-1 autocrine system, DNA replication, and nuclear mitotic division in the remaining viable cardiac myocytes.
Experimental cell research 1994;213(2):463-72.
1994: Jan Kajstura; Xiaoping Zhang; K Reiss; E Szoke; P Li; Costanza Lagrasta; W Cheng; Zbigniew Darzynkiewicz; Giorgio Olivetti; Piero Anversa
Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats.
Circulation research 1994;74(3):383-400.
1993: K Reiss; Jan Kajstura; J M Capasso; T A Marino; Piero Anversa
Impairment of myocyte contractility following coronary artery narrowing is associated with activation of the myocyte IGF1 autocrine system, enhanced expression of late growth related genes, DNA synthesis, and myocyte nuclear mitotic division in rats.
Experimental cell research 1993;207(2):348-60.