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Tuula Kallunki

Research Profile

Living Beings

Physiology

Chemicals & Drugs

Anatomy

Phenomena

Phosphorylation

Disorders

Cell Transformation, Neoplastic

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Publications

TOP 3
Tuula Kallunki; O D Olsen; Marja Jäättelä
Cancer-associated lysosomal changes: friends or foes?
Bo Rafn; Tuula Kallunki
A way to invade: a story of ErbB2 and lysosomes.
Bo Rafn; Piotr Szyniarowski; Erkka Valo; Pekka Kohonen; José Moreira; Christian Friberg Nielsen; Jesper Nylandsted; Charlotta Johanne Olsen; Sofie Hagel Andersen; Trine Bøttzauw; Elisabeth Corcelle-Termeau; Mads Daugaard; Christina Egebjerg; Nicole Fehrenbacher; Sampsa Hautaniemi; Marja Jäättelä; Tuula Kallunki
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.

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All Publications

2013: Tuula Kallunki; O D Olsen; Marja Jäättelä
Cancer-associated lysosomal changes: friends or foes?
Oncogene 2013;32(16):1995-2004.
2012: Bo Rafn; Tuula Kallunki
A way to invade: a story of ErbB2 and lysosomes.
Cell cycle (Georgetown, Tex.) 2012;11(13):2415-6.
2012: Bo Rafn; Piotr Szyniarowski; Erkka Valo; Pekka Kohonen; José Moreira; Christian Friberg Nielsen; Jesper Nylandsted; Charlotta Johanne Olsen; Sofie Hagel Andersen; Trine Bøttzauw; Elisabeth Corcelle-Termeau; Mads Daugaard; Christina Egebjerg; Nicole Fehrenbacher; Sampsa Hautaniemi; Marja Jäättelä; Tuula Kallunki
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.
Molecular cell 2012;45(6):764-76.
2012: D P Mathiasen; C F Nielsen; Pietri Puustinen; B Rafn; S Tuomela; E Valo; Jukka Westermarck; B M Willumsen; S H Andersen; T Bøttzauw; Mads Daugaard; C Egebjerg; S Hautaniemi; Marja Jäättelä; A Khanna; R Lahesmaa; Tuula Kallunki
Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation.
Oncogene 2012;31(3):390-401.
2011: Piotr Szyniarowski; Tuula Kallunki; Jesper Nylandsted; Elisabeth Corcelle-Termeau; Thomas Farkas; Maria Høyer-Hansen; Marja Jäättelä
A comprehensive siRNA screen for kinases that suppress macroautophagy in optimal growth conditions.
Autophagy 2011;7(8):892-903.
2011: Nina Westerlund; Justyna Zdrojewska; Artur Padzik; Emilia Komulainen; Benny Björkblom; Emmy Rannikko; Tanya Tararuk; Cristina Garcia-Frigola; Jouko Sandholm; Laurent Nguyen; Tuula Kallunki; Michael J Courtney; Eleanor T Coffey
Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate.
Nature neuroscience 2011;14(3):305-13.
2008: Tiina Naumanen; Lars D. Johansen; Eleanor T Coffey; Tuula Kallunki
Loss-of-function of IKAP/ELP1: could neuronal migration defect underlie familial dysautonomia?
Cell adhesion & migration 2008;2(4):236-9.
2008: Antoine Mialon; Jacob Thastrup; Tuula Kallunki; Leni Mannermaa; Jukka Westermarck; Tim H Holmström
Identification of nucleolar effects in JNK-deficient cells.
FEBS letters 2008;582(20):3145-51.
2008: Lars D. Johansen; Tiina Naumanen; Astrid Knudsen; Nina Westerlund; Irina Gromova; Melissa Junttila; Christina Nielsen; Trine Bøttzauw; Aviva Tolkovsky; Jukka Westermarck; Eleanor T Coffey; Marja Jäättelä; Tuula Kallunki
IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.
Journal of cell science 2008;121(Pt 6):854-64.
2007: Melissa R Junttila; Pietri Puustinen; Minna Niemelä; Raija Ahola; Hugh Arnold; Trine Böttzauw; Risto Ala-Aho; Christina Nielsen; Johanna Ivaska; Yoichi Taya; Shi-Long Lu; Shujun Lin; Edward Chan; Xiao-Jing Wang; Reidar Grènman; Juergen Kast; Tuula Kallunki; Rosalie C Pelz; Veli-Matti Kähäri; Jukka Westermarck
CIP2A inhibits PP2A in human malignancies.
Cell 2007;130(1):51-62.
2007: Christina Nielsen; Jacob Thastrup; Trine Bøttzauw; Marja Jäättelä; Tuula Kallunki
c-Jun NH2-terminal kinase 2 is required for Ras transformation independently of activator protein 1.
Cancer research 2007;67(1):178-85.
2005: Mads Lerdrup; Christian Holmberg; N Dietrich; E Shaulian; Thomas Herdegen; Marja Jäättelä; Tuula Kallunki
Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis.
Biochimica et biophysica acta 2005;1745(1):29-37.
2005: Benny Björkblom; Nina Westerlund; Vesa Hongisto; Vladislav Komarovski; Jan-Jonas Filén; Tuula A Nyman; Tuula Kallunki; Michael J Courtney; Eleanor T Coffey
Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(27):6350-61.
2004: Nicole Fehrenbacher; Mads Gyrd-Hansen; Birgit Poulsen; Ute Felbor; Tuula Kallunki; Marianne Boes; Ekkehard Weber; Marcel Leist; Marja Jäättelä
Sensitization to the lysosomal cell death pathway upon immortalization and transformation.
Cancer research 2004;64(15):5301-10.
2004: N Dietrich; J Thastrup; Christian Holmberg; Mads Gyrd-Hansen; Nicole Fehrenbacher; Ulrik Lademann; Mads Lerdrup; Thomas Herdegen; Marja Jäättelä; Tuula Kallunki
JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways.
Cell death and differentiation 2004;11(3):301-13.
2002: Christian Holmberg; Sigal Katz; Mads Lerdrup; Thomas Herdegen; Marja Jäättelä; Ami Aronheim; Tuula Kallunki
A novel specific role for I kappa B kinase complex-associated protein in cytosolic stress signaling.
The Journal of biological chemistry 2002;277(35):31918-28.
2001: Jukka Westermarck; Song-Ping Li; Tuula Kallunki; Jiahuai Han; Veli-Matti Kähäri
p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression.
Molecular and cellular biology 2001;21(7):2373-83.
2001: Ulrik Lademann; Tuula Kallunki; Marja Jäättelä
A20 zinc finger protein inhibits TNF-induced apoptosis and stress response early in the signaling cascades and independently of binding to TRAF2 or 14-3-3 proteins.
Cell death and differentiation 2001;8(3):265-72.
2000: Jukka Westermarck; S Li; Panu M Jaakkola; Tuula Kallunki; Reidar Grénman; Veli-Matti Kähäri
Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2.
Cancer research 2000;60(24):7156-62.
1998: Marja Jäättelä; Dorte Wissing; K Kokholm; Tuula Kallunki; Mikala Egeblad
Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.
The EMBO journal 1998;17(21):6124-34.
1998: Thomas Herdegen; Francois Claret; Tuula Kallunki; Ana Martin Villalba; Christine Winter; Tony Hunter; Michael Karin
Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(14):5124-35.