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Amine Kamen

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Keith B Male; Johnny Montes; Amine Kamen; Alfred C W Leung; John H T Luong
Probing inhibitory effects of nanocrystalline cellulose: inhibition versus surface charge.
Wei Shao; Sana Abbasi; Parminder S Chahal; Amine Kamen; Jimmy A Mena; Johnny Montes; Arghya Paul; Satya Prakash
A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis.
Dormond Edwige; Amine Kamen
Manufacturing of adenovirus vectors: production and purification of helper dependent adenovirus.

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All Publications

2012: Keith B Male; Johnny Montes; Amine Kamen; Alfred C W Leung; John H T Luong
Probing inhibitory effects of nanocrystalline cellulose: inhibition versus surface charge.
Nanoscale 2012;4(4):1373-9.
2012: Wei Shao; Sana Abbasi; Parminder S Chahal; Amine Kamen; Jimmy A Mena; Johnny Montes; Arghya Paul; Satya Prakash
A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis.
International journal of nanomedicine 2012;7():1575-86.
2011: Dormond Edwige; Amine Kamen
Manufacturing of adenovirus vectors: production and purification of helper dependent adenovirus.
Methods in molecular biology (Clifton, N.J.) 2011;737():139-56.
2011: Julia Transfiguracion; Jimmy Mena; Marc G Aucoin; Amine Kamen
Development and validation of a HPLC method for the quantification of baculovirus particles.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2011;879(1):61-8.
2010: Khaled A Mahmoud; Jimmy Mena; Keith B Male; Sabahudin Hrapovic; Amine Kamen; John H T Luong
Effect of surface charge on the cellular uptake and cytotoxicity of fluorescent labeled cellulose nanocrystals.
ACS applied materials & interfaces 2010;2(10):2924-32.
2010: Dormond Edwige; Parminder S Chahal; Alice Bernier; Rosa Tran; Michel Perrier; Amine Kamen
An efficient process for the purification of helper-dependent adenoviral vector and removal of helper virus by iodixanol ultracentrifugation.
Journal of virological methods 2010;165(1):83-9.
2010: Jimmy Mena; Marc G Aucoin; Johnny Montes; Parminder S Chahal; Amine Kamen
Improving adeno-associated vector yield in high density insect cell cultures.
The journal of gene medicine 2010;12(2):157-67.
2010: María Mercedes Segura; Alain Garnier; Yves Durocher; Sven Ansorge; Amine Kamen
New protocol for lentiviral vector mass production.
Methods in molecular biology (Clifton, N.J.) 2010;614():39-52.
2010: Chun Fang Shen; Robert Voyer; Roseanne Tom; Amine Kamen
Reassessing culture media and critical metabolites that affect adenovirus production.
Biotechnology progress 2010;26(1):200-7.
2009: Sven Ansorge; Stéphane Lanthier; Julia Transfiguracion; Yves Durocher; Olivier Henry; Amine Kamen
Development of a scalable process for high-yield lentiviral vector production by transient transfection of HEK293 suspension cultures.
The journal of gene medicine 2009;11(10):868-76.
2009: Keith B Male; Yew-Min Tzeng; Johnny Montes; Bing-Lan Liu; Wan-Chun Liao; Amine Kamen; John H T Luong
Probing inhibitory effects of destruxins from Metarhizium anisopliae using insect cell based impedance spectroscopy: inhibition vs chemical structure.
The Analyst 2009;134(7):1447-52.
2009: Dormond Edwige; M Perrier; Amine Kamen
Identification of critical infection parameters to control helper-dependent adenoviral vector production.
Journal of biotechnology 2009;142(2):142-50.
2009: Dormond Edwige; Michel Perrier; Amine Kamen
From the first to the third generation adenoviral vector: what parameters are governing the production yield?
Biotechnology advances 2009;27(2):133-44.
2009: Dormond Edwige; A Meneses-Acosta; Danielle Jacob; Yves Durocher; R Gilbert; Michel Perrier; Amine Kamen
An efficient and scalable process for helper-dependent adenoviral vector production using polyethylenimine-adenofection.
Biotechnology and bioengineering 2009;102(3):800-10.
2008: Julia Transfiguracion; Alice Bernier; Robert Voyer; Helene Coelho; Matt Coffey; Amine Kamen
Rapid and reliable quantification of reovirus type 3 by high performance liquid chromatography during manufacturing of Reolysin.
Journal of pharmaceutical and biomedical analysis 2008;48(3):598-605.
2008: Keith B Male; Yerra Koteswara Rao; Yew-Min Tzeng; Johnny Montes; Amine Kamen; John H T Luong
Probing inhibitory effects of Antrodia camphorata isolates using insect cell-based impedance spectroscopy: inhibition vs chemical structure.
Chemical research in toxicology 2008;21(11):2127-33.
2008: Angélica Meneses-Acosta; Dormond Edwige; Danielle Jacob; Roseanne Tom; Alice Bernier; Sylvie Perret; Gilles St-Laurent; Yves Durocher; Rénald Gilbert; Amine Kamen
Development of a suspension serum-free helper-dependent adenovirus production system and assessment of co-infection conditions.
Journal of virological methods 2008;148(1-2):106-14.
2008: Maria Segura; Alain Garnier; Marcos Rafael Di Falco; Gavin Whissell; Angélica Meneses-Acosta; Normand Arcand; Amine Kamen
Identification of host proteins associated with retroviral vector particles by proteomic analysis of highly purified vector preparations.
Journal of virology 2008;82(3):1107-17.
2008: Marc G Aucoin; Michel Perrier; Amine Kamen
Critical assessment of current adeno-associated viral vector production and quantification methods.
Biotechnology advances 2008;26(1):73-88.
2007: Parminder S Chahal; Julia Transfiguracion; Alice Bernier; Robert Voyer; Matt Coffey; Amine Kamen
Validation of a high-performance liquid chromatographic assay for the quantification of Reovirus particles type 3.
Journal of pharmaceutical and biomedical analysis 2007;45(3):417-21.
2007: Maria Segura; Alain Garnier; Yves Durocher; Helene Coelho; Amine Kamen
Production of lentiviral vectors by large-scale transient transfection of suspension cultures and affinity chromatography purification.
Biotechnology and bioengineering 2007;98(4):789-99.
2007: Philippe-Alexandre Gilbert; Amine Kamen; Alice Bernier; Alain Garnier
A simple macroscopic model for the diffusion and adsorption kinetics of r-adenovirus.
Biotechnology and bioengineering 2007;98(1):239-51.
2007: Yves Durocher; Phuong Lan Pham; Gilles St-Laurent; Danielle Jacob; Brian Cass; Parminder S Chahal; Cara J Lau; Josephine Nalbantoglu; Amine Kamen
Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells.
Journal of virological methods 2007;144(1-2):32-40.
2007: Marc G Aucoin; Michel Perrier; Amine Kamen
Improving AAV vector yield in insect cells by modulating the temperature after infection.
Biotechnology and bioengineering 2007;97(6):1501-9.
2007: Julia Transfiguracion; Hasnaa Jorio; Jamal Meghrous; Danielle Jacob; Amine Kamen
High yield purification of functional baculovirus vectors by size exclusion chromatography.
Journal of virological methods 2007;142(1-2):21-8.
2007: Eric Carpentier; Sébastien Paris; Amine Kamen; Yves Durocher
Limiting factors governing protein expression following polyethylenimine-mediated gene transfer in HEK293-EBNA1 cells.
Journal of biotechnology 2007;128(2):268-80.
2007: Maria Segura; Amine Kamen; Marie-Claude Lavoie; Alain Garnier
Exploiting heparin-binding properties of MoMLV-based retroviral vectors for affinity chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;846(1-2):124-31.
2007: Marc G Aucoin; Danielle Jacob; Parminder S Chahal; Jamal Meghrous; Alice Bernier; Amine Kamen
Virus-like particle and viral vector production using the baculovirus expression vector system/insect cell system: adeno-associated virus-based products.
Methods in molecular biology (Clifton, N.J.) 2007;388():281-96.
2007: Cynthia B Elias; Barbara Jardin; Amine Kamen
Recombinant protein production in large-scale agitated bioreactors using the baculovirus expression vector system.
Methods in molecular biology (Clifton, N.J.) 2007;388():225-46.
2007: Parminder S Chahal; Marc G Aucoin; Amine Kamen
Primary recovery and chromatographic purification of adeno-associated virus type 2 produced by baculovirus/insect cell system.
Journal of virological methods 2007;139(1):61-70.
2006: Marc G Aucoin; Michel Perrier; Amine Kamen
Production of adeno-associated viral vectors in insect cells using triple infection: optimization of baculovirus concentration ratios.
Biotechnology and bioengineering 2006;95(6):1081-92.
2006: Karim Ghani; Alain Garnier; Helene Coelho; Julia Transfiguracion; Pierre Trudel; Amine Kamen
Retroviral vector production using suspension-adapted 293GPG cells in a 3L acoustic filter-based perfusion bioreactor.
Biotechnology and bioengineering 2006;95(4):653-60.
2006: Phuong Lan Pham; Amine Kamen; Yves Durocher
Large-scale transfection of mammalian cells for the fast production of recombinant protein.
Molecular biotechnology 2006;34(2):225-37.
2006: Hasnaa Jorio; Rosa Tran; Jamal Meghrous; Lucie Bourget; Amine Kamen
Analysis of baculovirus aggregates using flow cytometry.
Journal of virological methods 2006;134(1-2):8-14.
2006: Maria Segura; Amine Kamen; Alain Garnier
Downstream processing of oncoretroviral and lentiviral gene therapy vectors.
Biotechnology advances 2006;24(3):321-37.
2006: Maria Segura; Alain Garnier; Amine Kamen
Purification and characterization of retrovirus vector particles by rate zonal ultracentrifugation.
Journal of virological methods 2006;133(1):82-91.
2006: Hasnaa Jorio; Rosa Tran; Amine Kamen
Stability of serum-free and purified baculovirus stocks under various storage conditions.
Biotechnology progress 2006;22(1):319-25.
2005: Olivier Henry; Michel Perrier; Amine Kamen
Metabolic flux analysis of HEK-293 cells in perfusion cultures for the production of adenoviral vectors.
Metabolic engineering 2005;7(5-6):467-76.
2005: Maria Segura; Amine Kamen; Pierre Trudel; Alain Garnier
A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography.
Biotechnology and bioengineering 2005;90(4):391-404.
2005: Phuong Lan Pham; Sylvie Perret; Brian Cass; Eric Carpentier; Gilles St-Laurent; Louis Bisson; Amine Kamen; Yves Durocher
Transient gene expression in HEK293 cells: peptone addition posttransfection improves recombinant protein synthesis.
Biotechnology and bioengineering 2005;90(3):332-44.
2005: Brian Cass; Phuong Lan Pham; Amine Kamen; Yves Durocher
Purification of recombinant proteins from mammalian cell culture using a generic double-affinity chromatography scheme.
Protein expression and purification 2005;40(1):77-85.
2005: Jamal Meghrous; Marc G Aucoin; Danielle Jacob; Parminder S Chahal; Normand Arcand; Amine Kamen
Production of recombinant adeno-associated viral vectors using a baculovirus/insect cell suspension culture system: from shake flasks to a 20-L bioreactor.
Biotechnology progress 2005;21(1):154-60.
2005: Chouki Benslimane; Cynthia B Elias; Jalal Hawari; Amine Kamen
Insights into the central metabolism of Spodoptera frugiperda (Sf-9) and Trichoplusia ni BTI-Tn-5B1-4 (Tn-5) insect cells by radiolabeling studies.
Biotechnology progress 2005;21(1):78-86.
2004: Julia Transfiguracion; Helene Coelho; Amine Kamen
High-performance liquid chromatographic total particles quantification of retroviral vectors pseudotyped with vesicular stomatitis virus-G glycoprotein.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;813(1-2):167-73.
2004: Chun Fang Shen; Jalal Hawari; Amine Kamen
Micro-quantitation of lipids in serum-free cell culture media: a critical aspect is the minimization of interference from medium components and chemical reagents.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;810(1):119-27.
2004: Olivier Henry; Dormond Edwige; Michel Perrier; Amine Kamen
Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures.
Biotechnology and bioengineering 2004;86(7):765-74.
2004: Amine Kamen; Olivier Henry
Development and optimization of an adenovirus production process.
The journal of gene medicine 2004;6 Suppl 1():S184-92.
2003: Phuong Lan Pham; Sylvie Perret; Huyen Chau Doan; Brian Cass; Gilles St-Laurent; Amine Kamen; Yves Durocher
Large-scale transient transfection of serum-free suspension-growing HEK293 EBNA1 cells: peptone additives improve cell growth and transfection efficiency.
Biotechnology and bioengineering 2003;84(3):332-42.
2003: Julia Transfiguracion; Diana E Jaalouk; Karim Ghani; Jacques Galipeau; Amine Kamen
Size-exclusion chromatography purification of high-titer vesicular stomatitis virus G glycoprotein-pseudotyped retrovectors for cell and gene therapy applications.
Human gene therapy 2003;14(12):1139-53.
2003: Isabelle Nadeau; Amine Kamen
Production of adenovirus vector for gene therapy.
Biotechnology advances 2003;20(7-8):475-89.
2003: Cynthia B Elias; Eric Carpentier; Yves Durocher; Louis Bisson; Roland Wagner; Amine Kamen
Improving glucose and glutamine metabolism of human HEK 293 and Trichoplusia ni insect cells engineered to express a cytosolic pyruvate carboxylase enzyme.
Biotechnology progress 2003;19(1):90-7.
2002: Chun Fang Shen; Jamal Meghrous; Amine Kamen
Quantitation of baculovirus particles by flow cytometry.
Journal of virological methods 2002;105(2):321-30.
2002: Yves Durocher; Sylvie Perret; Amine Kamen
High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells.
Nucleic acids research 2002;30(2):E9.
2002: Isabelle Nadeau; Philippe-Alexandre Gilbert; D Jacob; Michel Perrier; Amine Kamen
Low-protein medium affects the 293SF central metabolism during growth and infection with adenovirus.
Biotechnology and bioengineering 2002;77(1):91-104.
2001: Eric Carpentier; D Lebesgue; Amine Kamen; M Hogue; Michel Bouvier; Yves Durocher
Increased production of active human beta(2)-adrenergic/G(alphas) fusion receptor in Sf-9 cells using nutrient limiting conditions.
Protein expression and purification 2001;23(1):66-74.
2001: Julia Transfiguracion; Alice Bernier; N Arcand; Parminder S Chahal; Amine Kamen
Validation of a high-performance liquid chromatographic assay for the quantification of adenovirus type 5 particles.
Journal of chromatography. B, Biomedical sciences and applications 2001;761(2):187-94.
2001: V Klyushnichenko; Alice Bernier; Amine Kamen; E Harmsen
Improved high-performance liquid chromatographic method in the analysis of adenovirus particles.
Journal of chromatography. B, Biomedical sciences and applications 2001;755(1-2):27-36.
2001: John H T Luong; Mehran Habibi-Rezaei; Jamal Meghrous; Caide Xiao; Keith B Male; Amine Kamen
Monitoring motility, spreading, and mortality of adherent insect cells using an impedance sensor.
Analytical chemistry 2001;73(8):1844-8.
2000: Isabelle Nadeau; J Sabatié; M Koehl; Michel Perrier; Amine Kamen
Human 293 cell metabolism in low glutamine-supplied culture: interpretation of metabolic changes through metabolic flux analysis.
Metabolic engineering 2000;2(4):277-92.
2000: Yves Durocher; Sylvie Perret; E Thibaudeau; M H Gaumond; Amine Kamen; Rino Stocco; Mark Abramovitz
A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture.
Analytical biochemistry 2000;284(2):316-26.
2000: Isabelle Nadeau; D Jacob; Michel Perrier; Amine Kamen
293SF metabolic flux analysis during cell growth and infection with an adenoviral vector.
Biotechnology progress 2000;16(5):872-84.
2000: A Zeiser; Cynthia B Elias; R Voyer; Barbara Jardin; Amine Kamen
On-line monitoring of physiological parameters of insect cell cultures during the growth and infection process.
Biotechnology progress 2000;16(5):803-8.
2000: Cynthia B Elias; A Zeiser; C Bédard; Amine Kamen
Enhanced growth of Sf-9 cells to a maximum density of 5.2 x 10(7) cells per mL and production of beta-galactosidase at high cell density by fed batch culture.
Biotechnology and bioengineering 2000;68(4):381-8.
1999: P Siegwart; J Côté; Keith B Male; John H T Luong; Michel Perrier; Amine Kamen
Adaptive control at low glucose concentration of HEK-293 cell serum-free cultures.
Biotechnology progress 1999;15(4):608-16.
1999: A Zeiser; C Bédard; R Voyer; Barbara Jardin; R Tom; Amine Kamen
On-line monitoring of the progress of infection in Sf-9 insect cell cultures using relative permittivity measurements.
Biotechnology and bioengineering 1999;63(1):122-6.
1998: M Hahn; S Borisova; Joseph D Schrag; Daniel C Tessier; A Zapun; R Tom; Amine Kamen; John J M Bergeron; David Y Thomas; Miroslaw Cygler
Identification and crystallization of a protease-resistant core of calnexin that retains biological activity.
Journal of structural biology 1998;123(3):260-4.
1998: J Côté; Alain Garnier; Bernard Massie; Amine Kamen
Serum-free production of recombinant proteins and adenoviral vectors by 293SF-3F6 cells.
Biotechnology and bioengineering 1998;59(5):567-75.
1997: J Côté; Lucie Bourget; Alain Garnier; Amine Kamen
Study of adenovirus production in serum-free 293SF suspension culture by GFP-expression monitoring.
Biotechnology progress 1997;13(6):709-14.
1997: Keith B Male; P O Gartu; Amine Kamen; John H T Luong
On-line monitoring of glucose in mammalian cell culture using a flow injection analysis (FIA) mediated biosensor.
Biotechnology and bioengineering 1997;55(3):497-504.
1996: Isabelle Nadeau; Alain Garnier; J Côté; Bernard Massie; C Chavarie; Amine Kamen
Improvement of recombinant protein production with the human adenovirus/293S expression system using fed-batch strategies.
Biotechnology and bioengineering 1996;51(6):613-23.
1996: Amine Kamen; C Bédard; R Tom; S Perret; B Jardin
On-line monitoring of respiration in recombinant-baculovirus infected and uninfected insect cell bioreactor cultures.
Biotechnology and bioengineering 1996;50(1):36-48.
1996: A Garnier; Barbara Jardin; Sylvie Perret; R Tom; R Voyer; Amine Kamen
Dissolved carbon dioxide accumulation in a large scale and high density production of TGFβ receptor with baculovirus infected Sf-9 cells.
Cytotechnology 1996;22(1-3):53-63.
1995: R L Tom; M T Debanne; C Bédard; A W Caron; B Massie; Amine Kamen
Improved yields of the extracellular domain of the epidermal growth factor receptor produced using the baculovirus expression system by medium replacement following infection.
Applied microbiology and biotechnology 1995;44(1-2):53-8.
1995: R L Tom; A W Caron; B Massie; Amine Kamen
Scale-up of recombinant virus and protein production in stirred-tank reactors.
Methods in molecular biology (Clifton, N.J.) 1995;39():203-24.
1994: Alain Garnier; J Côté; I Nadeau; Amine Kamen; B Massie
Scale-up of the adenovirus expression system for the production of recombinant protein in human 293S cells.
Cytotechnology 1994;15(1-3):145-55.
1994: C Bédard; Amine Kamen; R Tom; B Massie
Maximization of recombinant protein yield in the insect cell/baculovirus system by one-time addition of nutrients to high-density batch cultures.
Cytotechnology 1994;15(1-3):129-38.
1993: C Bédard; R Tom; Amine Kamen
Growth, nutrient consumption, and end-product accumulation in Sf-9 and BTI-EAA insect cell cultures: insights into growth limitation and metabolism.
Biotechnology progress 1993;9(6):615-24.