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Jan Kamps

Research Profile

Chemicals & Drugs

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Rats
Mouse

Anatomy

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J M Kułdo; Grietje Molema; K I Ogawara; Marianne G Rots; J A C Schalk; C Trautwein; P J Zwiers; Sigridur A Asgeirsdóttir; B Banas; Anna Rita Bellu; Hidde J Haisma; Jan A A M Kamps
Targeted adenovirus mediated inhibition of NF-κB-dependent inflammatory gene expression in endothelial cells in vitro and in vivo.
Sigridur A Asgeirsdóttir; B Banas; Peter Heeringa; Jan A A M Kamps; N F Kurniati; P W Mathieson; T J Rabelink; M A Saleem; S C Satchell; M van Meurs; C van Solingen; A J van Zonneveld; P J Zwiers; Grietje Molema
MicroRNA-126 contributes to renal microvascular heterogeneity of VCAM-1 protein expression in acute inflammation.
Piotr S Kowalski; Niek G J Leus; Marcel H J Ruiters; Gerrit L Scherphof; Jan A A M Kamps; Grietje Molema
Targeted siRNA delivery to diseased microvascular endothelial cells: cellular and molecular concepts.

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All Publications

2013: J M Kułdo; Grietje Molema; K I Ogawara; Marianne G Rots; J A C Schalk; C Trautwein; P J Zwiers; Sigridur A Asgeirsdóttir; B Banas; Anna Rita Bellu; Hidde J Haisma; Jan A A M Kamps
Targeted adenovirus mediated inhibition of NF-κB-dependent inflammatory gene expression in endothelial cells in vitro and in vivo.
Journal of controlled release : official journal of the Controlled Release Society 2013;166(1):57-65.
2012: Sigridur A Asgeirsdóttir; B Banas; Peter Heeringa; Jan A A M Kamps; N F Kurniati; P W Mathieson; T J Rabelink; M A Saleem; S C Satchell; M van Meurs; C van Solingen; A J van Zonneveld; P J Zwiers; Grietje Molema
MicroRNA-126 contributes to renal microvascular heterogeneity of VCAM-1 protein expression in acute inflammation.
American journal of physiology. Renal physiology 2012;302(12):F1630-9.
2011: Piotr S Kowalski; Niek G J Leus; Marcel H J Ruiters; Gerrit L Scherphof; Jan A A M Kamps; Grietje Molema
Targeted siRNA delivery to diseased microvascular endothelial cells: cellular and molecular concepts.
IUBMB life 2011;63(8):648-58.
2010: Joanna E Adrian; Henriëtte W M Morselt; Regine Süss; Sabine Barnert; Jan Willem Kok; Sigridur A Asgeirsdóttir; Marcel H J Ruiters; Grietje Molema; Jan A A M Kamps
Targeted SAINT-O-Somes for improved intracellular delivery of siRNA and cytotoxic drugs into endothelial cells.
Journal of controlled release : official journal of the Controlled Release Society 2010;144(3):341-9.
2010: Sigridur A Asgeirsdóttir; Eduard G Talman; Inge A de Graaf; Jan A A M Kamps; Simon C Satchell; Peter W Mathieson; Marcel H J Ruiters; Grietje Molema
Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro--a quantitative study.
Journal of controlled release : official journal of the Controlled Release Society 2010;141(2):241-51.
2008: Hidde J Haisma; Jan A A M Kamps; Gera K Kamps; Josee A Plantinga; Marianne G Rots; Anna Rita Bellu
Polyinosinic acid enhances delivery of adenovirus vectors in vivo by preventing sequestration in liver macrophages.
The Journal of general virology 2008;89(Pt 5):1097-105.
2008: Sigridur A Asgeirsdóttir; Peter J Zwiers; Henriëtte W M Morselt; Henk E Moorlag; Hester I Bakker; Peter Heeringa; Jan Willem Kok; Cees G M Kallenberg; Grietje Molema; Jan A A M Kamps
Inhibition of proinflammatory genes in anti-GBM glomerulonephritis by targeted dexamethasone-loaded AbEsel liposomes.
American journal of physiology. Renal physiology 2008;294(3):F554-61.
2007: Alida H Weeke-Klimp; Martin Bartsch; Henriëtte W M Morselt; Ingrid Van Veen-Hof; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Targeting of stabilized plasmid lipid particles to hepatocytes in vivo by means of coupled lactoferrin.
Journal of drug targeting 2007;15(9):585-94.
2007: Sigridur A Asgeirsdóttir; Jan A A M Kamps; Hester I Bakker; Peter J Zwiers; Peter Heeringa; Karen van der Weide; Harry van Goor; Arjen H Petersen; Henriëtte W M Morselt; Henk E Moorlag; E Steenbergen; Cees G M Kallenberg; Grietje Molema
Site-specific inhibition of glomerulonephritis progression by targeted delivery of dexamethasone to glomerular endothelium.
Molecular pharmacology 2007;72(1):121-31.
2007: Joanna E Adrian; Jan A A M Kamps; Gerrit L Scherphof; Dirk K F Meijer; Anne-miek Van Loenen-Weemaes; Catharina Reker-Smit; Peter Terpstra; Klaas Poelstra
A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats.
Biochimica et biophysica acta 2007;1768(6):1430-9.
2007: Joanna E Adrian; Klaas Poelstra; Gerrit L Scherphof; Dirk K F Meijer; Anne-miek Van Loenen-Weemaes; Catharina Reker-Smit; Henriëtte W M Morselt; Peter Zwiers; Jan A A M Kamps
Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats.
The Journal of pharmacology and experimental therapeutics 2007;321(2):536-43.
2007: Paul de Vos; Bart J De Haan; Jan A A M Kamps; Marijke M Faas; Toshio Kitano
Zeta-potentials of alginate-PLL capsules: a predictive measure for biocompatibility?
Journal of biomedical materials research. Part A 2007;80(4):813-9.
2007: Joanna E Adrian; Klaas Poelstra; Jan A A M Kamps
Addressing liver fibrosis with liposomes targeted to hepatic stellate cells.
Journal of liposome research 2007;17(3-4):205-18.
2007: Joanna E Adrian; Jan A A M Kamps; Klaas Poelstra; Gerrit L Scherphof; Dirk K F Meijer; Yasufumi Kaneda
Delivery of viral vectors to hepatic stellate cells in fibrotic livers using HVJ envelopes fused with targeted liposomes.
Journal of drug targeting 2007;15(1):75-82.
2006: Joanna E Adrian; Klaas Poelstra; Gerrit L Scherphof; Grietje Molema; Dirk K F Meijer; Catharina Reker-Smit; Henriëtte W M Morselt; Jan A A M Kamps
Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems.
Journal of hepatology 2006;44(3):560-7.
2005: Xuedong Yan; Folkert Kuipers; Louis M Havekes; Rick Havinga; Bert Dontje; Klaas Poelstra; Gerrit L Scherphof; Jan A A M Kamps
The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse.
Biochemical and biophysical research communications 2005;328(1):57-62.
2005: Martin Bartsch; Alida H Weeke-Klimp; Henriëtte W M Morselt; Andrea Kimpfler; Sigridur A Asgeirsdóttir; Rolf Schubert; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Optimized targeting of polyethylene glycol-stabilized anti-intercellular adhesion molecule 1 oligonucleotide/lipid particles to liver sinusoidal endothelial cells.
Molecular pharmacology 2005;67(3):883-90.
2005: C Rothkopf; Alfred Fahr; Gert Fricker; Gerrit L Scherphof; Jan A A M Kamps
Uptake of phosphatidylserine-containing liposomes by liver sinusoidal endothelial cells in the serum-free perfused rat liver.
Biochimica et biophysica acta 2005;1668(1):10-6.
2005: Xuedong Yan; Gerrit L Scherphof; Jan A A M Kamps
Liposome opsonization.
Journal of liposome research 2005;15(1-2):109-39.
2005: Martin Bartsch; Alida H Weeke-Klimp; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Cell-specific targeting of lipid-based carriers for ODN and DNA.
Journal of liposome research 2005;15(1-2):59-92.
2005: Joanna M Kułdo; Ken Ichi Ogawara; Naomi Werner; Sigridur A Asgeirsdóttir; Jan A A M Kamps; Robbert J Kok; Grietje Molema
Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases.
Current vascular pharmacology 2005;3(1):11-39.
2005: Ekkehard Sturm; Rick Havinga; Julius F W Baller; Henk Wolters; Nico van Rooijen; Jan A A M Kamps; Henkjan J Verkade; Saul J Karpen; Folkert Kuipers
Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats.
Journal of hepatology 2005;42(1):102-9.
2004: X Yan; Klaas Poelstra; Gerrit L Scherphof; Jan A A M Kamps
A role for scavenger receptor B-I in selective transfer of rhodamine-PE from liposomes to cells.
Biochemical and biophysical research communications 2004;325(3):908-14.
2004: X Yan; Henriëtte W M Morselt; Gerrit L Scherphof; Klaas Poelstra; Jan A A M Kamps
The role of beta2-glycoprotein I in liposome-hepatocyte interaction.
Biochimica et biophysica acta 2004;1667(2):208-14.
2004: Martin Bartsch; Alida H Weeke-Klimp; Evelien P D Hoenselaar; Marc Stuart; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Stabilized lipid coated lipoplexes for the delivery of antisense oligonucleotides to liver endothelial cells in vitro and in vivo.
Journal of drug targeting 2004;12(9-10):613-21.
2004: Jan A A M Kamps; Gerrit L Scherphof
Biodistribution and uptake of liposomes in vivo.
Methods in enzymology 2004;387():257-66.
2003: Gerben A Koning; Henriëtte W M Morselt; Arko Gorter; Theresa M Allen; Samuel Zalipsky; Gerrit L Scherphof; Jan A A M Kamps
Interaction of differently designed immunoliposomes with colon cancer cells and Kupffer cells. An in vitro comparison.
Pharmaceutical research 2003;20(8):1249-57.
2003: Gerd Bendas; Ulrich Rothe; Gerrit L Scherphof; Jan A A M Kamps
The influence of repeated injections on pharmacokinetics and biodistribution of different types of sterically stabilized immunoliposomes.
Biochimica et biophysica acta 2003;1609(1):63-70.
2002: Martin Bartsch; Alida H Weeke-Klimp; Dirk K F Meijer; Gerrit L Scherphof; Jan A A M Kamps
Massive and selective delivery of lipid-coated cationic lipoplexes of oligonucleotides targeted in vivo to hepatic endothelial cells.
Pharmaceutical research 2002;19(5):676-80.
2002: Gerben A Koning; Jan A A M Kamps; Gerrit L Scherphof
Interference of macrophages with immunotargeting of liposomes.
Journal of liposome research 2002;12(1-2):107-19.
2002: Gerben A Koning; Jan A A M Kamps; Gerrit L Scherphof
Efficient intracellular delivery of 5-fluorodeoxyuridine into colon cancer cells by targeted immunoliposomes.
Cancer detection and prevention 2002;26(4):299-307.
2002: Ewa Zant-Przeworska; Jan A A M Kamps; Anton J M Roks; Wiek H Gilst; Gerrit L Scherphof
Development of liposomal gene targeting for therapeutic intervention or prevention of restenosis.
Cellular & molecular biology letters 2002;7(2):268-9.
2002: Gerrit L Scherphof; Gerben A Koning; Martin Bartsch; Xuedong Yan; Jan A A M Kamps
Targeting liposomes and lipoplexes to cells in the liver.
Cellular & molecular biology letters 2002;7(2):251-4.
2001: Gerben A Koning; Henriëtte W M Morselt; Arko Gorter; Theresa M Allen; Samuel Zalipsky; Jan A A M Kamps; Gerrit L Scherphof
Pharmacokinetics of differently designed immunoliposome formulations in rats with or without hepatic colon cancer metastases.
Pharmaceutical research 2001;18(9):1291-8.
2001: Gerrit L Scherphof; Jan A A M Kamps
The role of hepatocytes in the clearance of liposomes from the blood circulation.
Progress in lipid research 2001;40(3):149-66.
2000: Jan A A M Kamps; Gerben A Koning; Maria J Velinova; Henriëtte W M Morselt; M Wilkens; Arko Gorter; J Donga; Gerrit L Scherphof
Uptake of long-circulating immunoliposomes, directed against colon adenocarcinoma cells, by liver metastases of colon cancer.
Journal of drug targeting 2000;8(4):235-45.
1999: Gerben A Koning; Henriëtte W M Morselt; Maria J Velinova; J Donga; Arko Gorter; Theresa M Allen; Samuel Zalipsky; Jan A A M Kamps; Gerrit L Scherphof
Selective transfer of a lipophilic prodrug of 5-fluorodeoxyuridine from immunoliposomes to colon cancer cells.
Biochimica et biophysica acta 1999;1420(1-2):153-67.
1999: Gerben A Koning; Arko Gorter; Gerrit L Scherphof; Jan A A M Kamps
Antiproliferative effect of immunoliposomes containing 5-fluorodeoxyuridine-dipalmitate on colon cancer cells.
British journal of cancer 1999;80(11):1718-25.
1999: Jan A A M Kamps; Henriëtte W M Morselt; Gerrit L Scherphof
Uptake of liposomes containing phosphatidylserine by liver cells in vivo and by sinusoidal liver cells in primary culture: in vivo-in vitro differences.
Biochemical and biophysical research communications 1999;256(1):57-62.
1997: Jan A A M Kamps; Henriëtte W M Morselt; P J Swart; Dirk K F Meijer; Gerrit L Scherphof
Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11681-5.
1997: Klaas Poelstra; Winston W Bakker; Pieter A Klok; Jan A A M Kamps; M J Hardonk; D K Meijer
Dephosphorylation of endotoxin by alkaline phosphatase in vivo.
The American journal of pathology 1997;151(4):1163-9.
1997: K Shimada; Jan A A M Kamps; Joke Regts; K Ikeda; T Shiozawa; S Hirota; Gerrit L Scherphof
Biodistribution of liposomes containing synthetic galactose-terminated diacylglyceryl-poly(ethyleneglycol)s.
Biochimica et biophysica acta 1997;1326(2):329-41.
1996: Jan A A M Kamps; Pieter J Swart; Henriëtte W M Morselt; R Pauwels; Marie-Pierre de Bethune; E De Clercq; Dirk K F Meijer; Gerrit L Scherphof
Preparation and characterization of conjugates of (modified) human serum albumin and liposomes: drug carriers with an intrinsic anti-HIV activity.
Biochimica et biophysica acta 1996;1278(2):183-90.