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Thomas Kamradt

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Magdalena Huber; Katharina Jeltsch; Thomas Kamradt; Nadine Bollig; Dirk Brenner; Anne Brüstle; Thorsten Buch; Anna Guralnik; Christina Heinemann; Sylvia Heink; Tak W Mak; Hans-Willi Mittrücker; Axel Pagenstecher; Olivia Prazeres da Costa; Katharina Reinhard; Josephine Ritter; Björn Tackenberg; Alexander Visekruna; Eva Wittmann; Michael Lohoff
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis.
Thomas Kamradt; Andreas Radbruch; Hyun-Dong Chang
[Bad memories: understanding and removal of pathogenic consequences of immunological memory in inflammatory rheumatic diseases. The IMPAM consortium].
Thomas Dörner; E Genth; K Hartung; Thomas Kamradt; R Mierau; C Specker; Gerd R Burmester; U von Hinüber
[Recommendations of the Laboratory Commission of the German Society of Rheumatology (DGRh) on further training of rheumatologists in the field of rheumatological and immunological laboratory diagnostics].

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All Publications

2013: Magdalena Huber; Katharina Jeltsch; Thomas Kamradt; Nadine Bollig; Dirk Brenner; Anne Brüstle; Thorsten Buch; Anna Guralnik; Christina Heinemann; Sylvia Heink; Tak W Mak; Hans-Willi Mittrücker; Axel Pagenstecher; Olivia Prazeres da Costa; Katharina Reinhard; Josephine Ritter; Björn Tackenberg; Alexander Visekruna; Eva Wittmann; Michael Lohoff
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis.
The Journal of clinical investigation 2013;123(1):247-60.
2012: Thomas Kamradt; Andreas Radbruch; Hyun-Dong Chang
[Bad memories: understanding and removal of pathogenic consequences of immunological memory in inflammatory rheumatic diseases. The IMPAM consortium].
Zeitschrift für Rheumatologie 2012;71(6):501-3.
2012: Thomas Dörner; E Genth; K Hartung; Thomas Kamradt; R Mierau; C Specker; Gerd R Burmester; U von Hinüber
[Recommendations of the Laboratory Commission of the German Society of Rheumatology (DGRh) on further training of rheumatologists in the field of rheumatological and immunological laboratory diagnostics].
Zeitschrift für Rheumatologie 2012;71(4):328-9.
2012: Martina Weber; Debra Weih; David E Briles; Ralf A Claus; Hans-Peter Deigner; Nadine Ding; David P Enot; Lucien Frappart; Stefanie Henken; Emeka I Igwe; Thomas Kamradt; Michael Kiehntopf; Matthias Kohl; Sandro Lambeck; Ulrich A Maus; Abiodun D Ogunniyi; James C Paton; Yoram Vodovotz; Michael Bauer
Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(6):2424-36.
2011: Hyun-Dong Chang; Thomas Kamradt; H Schulze-Koops
[Th1, Th17 and Th1+17 cells].
Zeitschrift für Rheumatologie 2011;70(10):862-5.
2011: Hyun-Dong Chang; Thomas Kamradt
[Intestinal microbiota as regulator of the immune system].
Zeitschrift für Rheumatologie 2011;70(9):790-2.
2011: Luciana Berod; Christina Heinemann; Sylvia Heink; Angelika Escher; Christine Stadelmann; Sebastian Drube; Reinhard Wetzker; Johannes Norgauer; Thomas Kamradt
PI3Kγ deficiency delays the onset of experimental autoimmune encephalomyelitis and ameliorates its clinical outcome.
European journal of immunology 2011;41(3):833-44.
2011: Oliver Frey; Tania Mitera; Hilde Kelchtermans; Evelien Schurgers; Thomas Kamradt; Patrick Matthys
Ameliorated course of glucose-6-phosphate isomerase (G6PI)-induced arthritis in IFN-γ receptor knockout mice exposes an arthritis-promoting role of IFN-γ.
Journal of autoimmunity 2011;36(2):161-9.
2011: Oliver Frey; Lisa Bruns; Kyri Dunussi-Joannopoulos; Lars Morawietz; Thomas Kamradt
B cell depletion reduces the number of autoreactive T helper cells and prevents glucose-6-phosphate isomerase-induced arthritis.
PloS one 2011;6(9):e24718.
2011: Thomas Kamradt; Hyun-Dong Chang
Diversity and flexibility of Th17 effector functions.
Arthritis research & therapy 2011;13(2):106.
2011: Oliver Frey; Thomas Kamradt
[Biologics. Magic bullets - magic effects - magic costs? New therapeutics and their effects].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2011;108(1):7-12.
2010: Maria H Lexberg; Annegret Taubner; Inka Albrecht; Inga Lepenies; Anne Richter; Thomas Kamradt; Andreas Radbruch; Hyun-Dong Chang
IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells.
European journal of immunology 2010;40(11):3017-27.
2010: K Truta-Feles; Mariana Lagadari; K Lehmann; Luciana Berod; S Cubillos; S Piehler; Y Herouy; Dagmar Barz; Thomas Kamradt; Azzam A Maghazachi; Johannes Norgauer
Histamine modulates γδ-T lymphocyte migration and cytotoxicity, via Gi and Gs protein-coupled signalling pathways.
British journal of pharmacology 2010;161(6):1291-300.
2010: Oliver Frey; Juliane Meisel; Andreas Hutloff; Kerstin Bonhagen; Lisa Bruns; Richard A Kroczek; Lars Morawietz; Thomas Kamradt
Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis.
Annals of the rheumatic diseases 2010;69(8):1495-501.
2010: Oliver Frey; Andreas Reichel; Kerstin Bonhagen; Lars Morawietz; Una Rauchhaus; Thomas Kamradt
Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis.
Annals of the rheumatic diseases 2010;69(8):1511-8.
2010: Ingo M Irmler; Thomas Opfermann; Peter Gebhardt; Mieczyslaw Gajda; Rolf Bräuer; Hans P Saluz; Thomas Kamradt
In vivo molecular imaging of experimental joint inflammation by combined (18)F-FDG positron emission tomography and computed tomography.
Arthritis research & therapy 2010;12(6):R203.
2010: Thomas Kamradt; Oliver Frey
Arthritis: where are the T cells?
Arthritis research & therapy 2010;12(3):122.
2009: Melba Muñoz; Markus M Heimesaat; Kerstin Danker; Daniela Struck; Uwe Lohmann; Rita Plickert; Stefan Bereswill; André Fischer; Ildikò Rita Dunay; Kerstin Wolk; Christoph Loddenkemper; Hans-Willi Krell; Claude Libert; Leif R Lund; Oliver Frey; Christoph Hölscher; Yoichiro Iwakura; Nico Ghilardi; Wenjun Ouyang; Thomas Kamradt; Robert Sabat; Oliver Liesenfeld
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.
The Journal of experimental medicine 2009;206(13):3047-59.
2009: Mariana Lagadari; Krisztina Truta-Feles; Katja Lehmann; Luciana Berod; Mirjana Ziemer; Marco Idzko; Dagmar Barz; Thomas Kamradt; Azzam A Maghazachi; Johannes Norgauer
Lysophosphatidic acid inhibits the cytotoxic activity of NK cells: involvement of Gs protein-mediated signaling.
International immunology 2009;21(6):667-77.
2008: Maria H Lexberg; Annegret Taubner; Anna Förster; Inka Albrecht; Anne Richter; Thomas Kamradt; Andreas Radbruch; Hyun-Dong Chang
Th memory for interleukin-17 expression is stable in vivo.
European journal of immunology 2008;38(10):2654-64.
2008: Jan D Lünemann; Oliver Frey; Thorsten Eidner; Michael Baier; Susanne Roberts; Junji Sashihara; Rudolf Volkmer; Jeffrey I Cohen; Gert Hein; Thomas Kamradt; Christian Münz
Increased frequency of EBV-specific effector memory CD8+ T cells correlates with higher viral load in rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):991-1000.
2007: Anne Brüstle; Sylvia Heink; Magdalena Huber; Christine Rosenplänter; Christine Stadelmann; Philipp Yu; Enrico Arpaia; Tak W Mak; Thomas Kamradt; Michael Lohoff
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4.
Nature immunology 2007;8(9):958-66.
2007: Jan D Lünemann; Thomas Kamradt; Roland Martin; Christian Münz
Epstein-barr virus: environmental trigger of multiple sclerosis?
Journal of virology 2007;81(13):6777-84.
2007: Nadine Lanzke; Robin Kleinwächter; Saskia Kerschischnik; Lilit Sargsyan; David A Groneberg; Thomas Kamradt; Oliver Liesenfeld; Veit Krenn; Michael Sander; Claudia Spies
Differential effects of ethanol on IFN-gamma- and TNF-alpha-producing splenic T lymphocytes in a murine model of gram-negative pneumonia.
Addiction biology 2007;12(1):59-68.
2007: Mischo Kursar; Markus Koch; Hans-Willi Mittrücker; Geraldine Nouailles; Kerstin Bonhagen; Thomas Kamradt; Stefan H E Kaufmann
Cutting Edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2661-5.
2007: Thomas Kamradt
[Th17 cells].
Zeitschrift für Rheumatologie 2007;66(1):54-5.
2006: Ivana Durinovic-Belló; Silke Rosinger; Jennifer A Olson; Mauro Congia; Regina C Ahmad; Mathias Rickert; Johannes Hampl; Hubert Kalbacher; Jan Wouter Drijfhout; Elizabeth D Mellins; Sascha Al Dahouk; Thomas Kamradt; Markus J Maeurer; Carol Nhan; Bart O Roep; Bernhard O Boehm; Constantin Polychronakos; Gerald Nepom; Wolfram Karges; Hugh McDevitt; Grete Sønderstrup
DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(31):11683-8.
2006: Thomas Fischer; Ines Gemeinhardt; Susanne Wagner; Dorothee V Stieglitz; Jörg Schnorr; Kay-Geert A Hermann; Bernd Ebert; Diethard Petzelt; Rainer Macdonald; Kai Licha; Michael Schirner; Veit Krenn; Thomas Kamradt; Matthias Taupitz
Assessment of unspecific near-infrared dyes in laser-induced fluorescence imaging of experimental arthritis.
Academic radiology 2006;13(1):4-13.
2006: Gudrun F Debes; Martin E Dahl; Azita J Mahiny; Kerstin Bonhagen; Daniel J Campbell; Kerstin Siegmund; Klaus J Erb; David B Lewis; Thomas Kamradt; Alf Hamann
Chemotactic responses of IL-4-, IL-10-, and IFN-gamma-producing CD4+ T cells depend on tissue origin and microbial stimulus.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):557-66.
2005: Axel Nogai; Volker Siffrin; Kerstin Bonhagen; Caspar F Pfueller; Thordis Hohnstein; Rudolf Volkmer-Engert; Wolfgang Brück; Christine Stadelmann; Thomas Kamradt
Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):959-66.
2005: Thomas Kamradt
Can infections prevent or cure allergy and autoimmunity?
Discovery medicine 2005;5(27):283-7.
2005: Thomas Kamradt; Rolf Göggel; Klaus J Erb
Induction, exacerbation and inhibition of allergic and autoimmune diseases by infection.
Trends in immunology 2005;26(5):260-7.
2005: Robert Bockermann; David Schubert; Thomas Kamradt; Rikard Holmdahl
Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase.
Arthritis research & therapy 2005;7(6):R1316-24.
2005: Thomas Kamradt; David Schubert
The role and clinical implications of G6PI in experimental models of rheumatoid arthritis.
Arthritis research & therapy 2005;7(1):20-8.
2004: Pia Svendsen; Claus B Andersen; Nick Willcox; Anthony J Coyle; Rikard Holmdahl; Thomas Kamradt; Lars Fugger
Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):7037-45.
2004: Ute Kretschmer; Kerstin Bonhagen; Gudrun F Debes; Hans-Willi Mittrücker; Klaus J Erb; Oliver Liesenfeld; Dietmar M W Zaiss; Thomas Kamradt; Uta Syrbe; Alf Hamann
Expression of selectin ligands on murine effector and IL-10-producing CD4+ T cells from non-infected and infected tissues.
European journal of immunology 2004;34(11):3070-81.
2004: Gudrun F Debes; Kerstin Bonhagen; Thorsten Wolff; Ute Kretschmer; Stefan Krautwald; Thomas Kamradt; Alf Hamann
CC chemokine receptor 7 expression by effector/memory CD4+ T cells depends on antigen specificity and tissue localization during influenza A virus infection.
Journal of virology 2004;78(14):7528-35.
2004: David Schubert; Bert Maier; Lars Morawietz; Veit Krenn; Thomas Kamradt
Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4503-9.
2004: Ana Misslitz; Kerstin Bonhagen; Dorothee Harbecke; Christoph Lippuner; Thomas Kamradt; Toni Aebischer
Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection.
European journal of immunology 2004;34(3):715-25.
2004: Thomas Kamradt; Rudolf Volkmer-Engert
Cross-reactivity of T lymphocytes in infection and autoimmunity.
Molecular diversity 2004;8(3):271-80.
2004: Mischo Kursar; Kerstin Bonhagen; Anne Köhler; Thomas Kamradt; Stefan H E Kaufmann; Hans-Willi Mittrücker
Antigen-specific CD8+ T cell responses in intestinal tissues during murine listeriosis.
Microbes and infection / Institut Pasteur 2004;6(1):8-16.
2003: Alberto Sánchez-Fueyo; Jane Tian; Dominic Picarella; Christoph Domenig; Xin Xiao Zheng; Catherine A Sabatos; Natasha Manlongat; Orissa Bender; Thomas Kamradt; Vijay K Kuchroo; José-Carlos Gutiérrez-Ramos; Anthony J Coyle; Terry B Strom
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.
Nature immunology 2003;4(11):1093-101.
2003: Kerstin Bonhagen; Oliver Liesenfeld; Miguel J Stadecker; Andreas Hutloff; Klaus J Erb; Anthony J Coyle; Martin Lipp; Richard A Kroczek; Thomas Kamradt
ICOS+ Th cells produce distinct cytokines in different mucosal immune responses.
European journal of immunology 2003;33(2):392-401.
2002: Mischo Kursar; Kerstin Bonhagen; Joachim Fensterle; Anne Köhler; Robert Hurwitz; Thomas Kamradt; Stefan H E Kaufmann; Hans-Willi Mittrücker
Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses.
The Journal of experimental medicine 2002;196(12):1585-92.
2002: Mischo Kursar; Kerstin Bonhagen; Anne Köhler; Thomas Kamradt; Stefan H E Kaufmann; Hans-Willi Mittrücker
Organ-specific CD4+ T cell response during Listeria monocytogenes infection.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6382-7.
2002: Jan D Lünemann; Sonia Waiczies; Stefan Ehrlich; Uwe Wendling; Bibiane Seeger; Thomas Kamradt; Frauke Zipp
Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):4881-8.
2002: David Schubert; Monika Schmidt; Dietmar M W Zaiss; Peter Jungblut; Thomas Kamradt
Autoantibodies to GPI and creatine kinase in RA.
Nature immunology 2002;3(5):411; author reply 412-3.
2002: Thomas Kamradt
Lyme disease and current aspects of immunization.
Arthritis research 2002;4(1):20-9.
2001: Gabriela Riemekasten; A Kawald; C Weiss; A Meine; Jeannette Marell; Rolf Klein; Berthold Hocher; C Meisel; Gert Hausdorf; Rudolf A Manz; Thomas Kamradt; Gerd R Burmester; Falk Hiepe
Strong acceleration of murine lupus by injection of the SmD1(83-119) peptide.
Arthritis and rheumatism 2001;44(10):2435-45.
2001: Thomas Kamradt; N A Mitchison
Tolerance and autoimmunity.
The New England journal of medicine 2001;344(9):655-64.
2001: C Meisel; Kerstin Bonhagen; Max Löhning; Anthony J Coyle; JC Gutierrez-Ramos; Andreas Radbruch; Thomas Kamradt
Regulation and function of T1/ST2 expression on CD4+ T cells: induction of type 2 cytokine production by T1/ST2 cross-linking.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3143-50.
2001: Thomas Kamradt; Thomas Rudel; Matthias Selbach; Ulrich E Schaible
A new home for infection research.
Trends in microbiology 2001;9(2):54-6.
2001: Thomas Kamradt; Thomas Rudel; S Englich; Ulrich E Schaible
Institution profile: the Max-Planck-Institute for Infection biology and German Center for Rheumatological Research.
Trends in microbiology 2001;9(2):93-4.
2000: C Infante-Duarte; H F Horton; Michael C Byrne; Thomas Kamradt
Microbial lipopeptides induce the production of IL-17 in Th cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6107-15.
2000: Bert Maier; M Molinger; Andrew P Cope; Lars Fugger; J Schneider-Mergener; Grete Sønderstrup; Thomas Kamradt; A Kramer
Multiple cross-reactive self-ligands for Borrelia burgdorferi-specific HLA-DR4-restricted T cells.
European journal of immunology 2000;30(2):448-57.
1999: Anthony J Coyle; C Lloyd; Jane Tian; T Nguyen; C Erikkson; L Wang; P Ottoson; P Persson; Tracy Delaney; S Lehar; S Lin; L Poisson; C Meisel; Thomas Kamradt; T Bjerke; D Levinson; Jose-Carlos Gutierrez-Ramos
Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses.
The Journal of experimental medicine 1999;190(7):895-902.
1999: Jane Grogan; A Kramer; A Nogai; L Dong; M Ohde; J Schneider-Mergener; Thomas Kamradt
Cross-reactivity of myelin basic protein-specific T cells with multiple microbial peptides: experimental autoimmune encephalomyelitis induction in TCR transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):3764-70.
1999: Marina Backhaus; Thomas Kamradt; Dieter Loreck
Sacroiliitis - it's not all B 27.
Zeitschrift für Rheumatologie 1999;58(4):213-7.
1999: Marina Backhaus; Thomas Kamradt; Dirk Sandrock; Dieter Loreck; J Fritz; K J Wolf; H Raber; Bernd Hamm; Gerd R Burmester; Matthias Bollow
Arthritis of the finger joints: a comprehensive approach comparing conventional radiography, scintigraphy, ultrasound, and contrast-enhanced magnetic resonance imaging.
Arthritis and rheumatism 1999;42(6):1232-45.
1999: Max Löhning; Jane Grogan; Anthony J Coyle; Maria Yazdanbakhsh; C Meisel; JC Gutierrez-Ramos; Andreas Radbruch; Thomas Kamradt
T1/ST2 expression is enhanced on CD4+ T cells from schistosome egg-induced granulomas: analysis of Th cell cytokine coexpression ex vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):3882-9.
1999: C Infante-Duarte; Thomas Kamradt
Th1/Th2 balance in infection.
Springer seminars in immunopathology 1999;21(3):317-38.
1998: Sarah Louise Parry; Frances C Hall; J Olson; Thomas Kamradt; Grete Sønderstrup
Autoreactivity versus autoaggression: a different perspective on human autoantigens.
Current opinion in immunology 1998;10(6):663-8.
1998: Max Löhning; A Stroehmann; Anthony J Coyle; Jane Grogan; S Lin; JC Gutierrez-Ramos; D Levinson; Andreas Radbruch; Thomas Kamradt
T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6930-5.
1998: Susanne Priem; Gerd R Burmester; Thomas Kamradt; K Wolbart; Michael G Rittig; Andreas Krause
Detection of Borrelia burgdorferi by polymerase chain reaction in synovial membrane, but not in synovial fluid from patients with persisting Lyme arthritis after antibiotic therapy.
Annals of the rheumatic diseases 1998;57(2):118-21.
1997: C Infante-Duarte; Thomas Kamradt
Lipopeptides of Borrelia burgdorferi outer surface proteins induce Th1 phenotype development in alphabeta T-cell receptor transgenic mice.
Infection and immunity 1997;65(10):4094-9.
1997: Susanne Priem; Michael G Rittig; Thomas Kamradt; Gerd R Burmester; Andreas Krause
An optimized PCR leads to rapid and highly sensitive detection of Borrelia burgdorferi in patients with Lyme borreliosis.
Journal of clinical microbiology 1997;35(3):685-90.
1996: Andreas Krause; Thomas Kamradt; Gerd R Burmester
Potential infectious agents in the induction of arthritides.
Current opinion in rheumatology 1996;8(3):203-9.
1995: Thomas Kamradt; Andreas Krause; Gerd R Burmester
A role for T cells in the pathogenesis of treatment-resistant Lyme arthritis.
Molecular medicine (Cambridge, Mass.) 1995;1(5):486-90.