FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Yae Kanai

Research Profile

Physiology

Disorders

Procedures

Immunohistochemistry

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Yoshimasa Saito; Hidekazu Suzuki; Hitoshi Tsugawa; Sana Hibino; Kenro Hirata; Hiroyuki Imaeda; Yae Kanai; Juntaro Matsuzaki; Hidetsugu Saito; Toshifumi Hibi
The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells.
Tohru Nakagawa; Hiroyuki Nakanishi; Yoshihiko Ogata; Eri Arai; Tomohiko Hara; Yae Kanai; Takashi Kawahara; Motokiyo Komiyama; Hiroyuki Fujimoto
Prognostic risk stratification of patients with urothelial carcinoma of the bladder with recurrence after radical cystectomy.
Shunsuke Kondo; Chigusa Morizane; Hidenori Ojima; Kazuaki Shimada; Kenji Tamura; Hitoshi Tsuda; Hideki Ueno; Jun Hashimoto; Masafumi Ikeda; Yae Kanai; Takuji Okusaka
Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Yae Kanai (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Yoshimasa Saito; Hidekazu Suzuki; Hitoshi Tsugawa; Sana Hibino; Kenro Hirata; Hiroyuki Imaeda; Yae Kanai; Juntaro Matsuzaki; Hidetsugu Saito; Toshifumi Hibi
The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells.
International journal of cancer. Journal international du cancer 2013;132(8):1751-60.
2013: Tohru Nakagawa; Hiroyuki Nakanishi; Yoshihiko Ogata; Eri Arai; Tomohiko Hara; Yae Kanai; Takashi Kawahara; Motokiyo Komiyama; Hiroyuki Fujimoto
Prognostic risk stratification of patients with urothelial carcinoma of the bladder with recurrence after radical cystectomy.
The Journal of urology 2013;189(4):1275-81.
2013: Shunsuke Kondo; Chigusa Morizane; Hidenori Ojima; Kazuaki Shimada; Kenji Tamura; Hitoshi Tsuda; Hideki Ueno; Jun Hashimoto; Masafumi Ikeda; Yae Kanai; Takuji Okusaka
Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma.
International journal of clinical oncology 2013;18(2):207-13.
2013: G Nishikawa; R Ogawa; Shigeki Sekine; H Taniguchi; Hitoshi Tsuda; K Tsuta; Nobuyoshi Hiraoka; R Kushima; A Matsubara; T Mori; Yae Kanai
Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms.
British journal of cancer 2013;108(4):951-8.
2013: Yoshinori Ino; Motoki Iwasaki; Yae Kanai; Tomoo Kosuge; Kazuaki Shimada; R Yamazaki-Itoh; Nobuyoshi Hiraoka
Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer.
British journal of cancer 2013;108(4):914-23.
2013: Akiko Matsubara; Shigeki Sekine; Hirokazu Taniguchi; Hitoshi Tsuda; Akihiko Yoshida; Masayuki Yoshida; Ryoji Kushima; Yae Kanai
Prevalence of MED12 mutations in uterine and extrauterine smooth muscle tumours.
Histopathology 2013;62(4):657-61.
2013: Akiko Matsubara; Reiko Ogawa; Shigeki Sekine; Hirokazu Taniguchi; Hitoshi Tsuda; Ryoji Kushima; Yae Kanai
Frequent GNAS and KRAS mutations in pyloric gland adenoma of the stomach and duodenum.
The Journal of pathology 2013;229(4):579-87.
2013: Takashi Sato; Kenzo Soejima; Koji Tsuta; Shun-ichi Watanabe; Eri Arai; Tomoko Betsuyaku; Takashi Kohno; Yae Kanai
DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma.
PloS one 2013;8(3):e59444.
2013: Yoshinori Ino; Yae Kanai; Tomoo Kosuge; Seiji Oguro; Kazuaki Shimada; Rie Yamazaki-Itoh; Jan Zavada; Nobuyoshi Hiraoka
Arginase II expressed in cancer-associated fibroblasts indicates tissue hypoxia and predicts poor outcome in patients with pancreatic cancer.
PloS one 2013;8(2):e55146.
2013: Kazuhiro Yamanoi; Ken Yamazaki; Hiroshi Uchida; Mariko Fukuma; Yae Kanai; Hitoshi Katai; Ryoji Kushima; Michiie Sakamoto
Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in gastric cancer.
Pathology international 2013;63(1):13-9.
2012: Tohru Nakagawa; Hiroyuki Nakanishi; Yae Kanai; Motokiyo Komiyama; Hiroyuki Fujimoto
Characteristics of lymph node metastases defining the outcome after radical cystectomy of urothelial bladder carcinoma.
Japanese journal of clinical oncology 2012;42(11):1066-72.
2012: Masayoshi Yamada; Ryoji Kushima; Reiko Ogawa; Shigeki Sekine; Hirokazu Taniguchi; Hitoshi Tsuda; Yae Kanai
Frequent activating GNAS mutations in villous adenoma of the colorectum.
The Journal of pathology 2012;228(1):113-8.
2012: Eri Arai; Suenori Chiku; Hiroyuki Fujimoto; Masahiro Gotoh; Taisuke Mori; Tohru Nakagawa; Yae Kanai
Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas.
Carcinogenesis 2012;33(8):1487-93.
2012: Takuma Hayashi; Nobuyoshi Hiraoka; Akiko Horiuchi; Tomoyuki Ichimura; Osamu Ishiko; Yae Kanai; Mari Kasai; Ryuichiro Nishimura; Kenji Sano; Tanri Shiozawa; Tamotsu Sudo; Nobuo Yaegashi; Hiroyuki Aburatani; Ikuo Konishi
Potential role of LMP2 as an anti-oncogenic factor in human uterine leiomyosarcoma: morphological significance of calponin h1.
FEBS letters 2012;586(13):1824-31.
2012: Shinji Kikuchi; Tomoko Maruyama; Takeshi Ito; Miwako Iwai; Yae Kanai; Masataka Onizuka; Mika Sakurai-Yageta; Yukio Sato; Yumi Tsuboi; Hitoshi Tsuda; Yoshinori Murakami
Expression of a splicing variant of the CADM1 specific to small cell lung cancer.
Cancer science 2012;103(6):1051-7.
2012: Yoko Tateno; Minoru Esaki; Yae Kanai; Hidenori Ojima; Kazuaki Shimada; Nobuyoshi Hiraoka
Morules in intraductal papillary mucinous neoplasm with an associated invasive carcinoma of the pancreas.
Pancreas 2012;41(4):651-2.
2012: Eri Arai; Hiroyuki Fujimoto; Tohru Nakagawa; Saori Wakai-Ushijima; Yae Kanai
DNA methyltransferase 3B expression is associated with poor outcome of stage I testicular seminoma.
Histopathology 2012;60(6B):E12-8.
2012: Takehisa Watanabe; Hidenori Ojima; Yutaka Sasaki; Sugiko Watanabe; Shinjiro Hino; Akiyuki Hirosue; Ko Ishihara; Yae Kanai; Mitsuyoshi Nakao
Higher-order chromatin regulation and differential gene expression in the human tumor necrosis factor/lymphotoxin locus in hepatocellular carcinoma cells.
Molecular and cellular biology 2012;32(8):1529-41.
2012: Linghua Wang; Shogo Yamamoto; Hiroki Yamaue; Seiko Hirono; Takayuki Isagawa; Minoru Isomura; Yae Kanai; Atsushi Kaneda; Tokuichi Kawaguchi; Yoshio Miki; Satsuki Murayama-Hosokawa; Genta Nagae; Koichi Nagasaki; Tetsuo Noda; Akio Saiura; Hiromi Sakamoto; Fei Sang; Tatsuhiro Shibata; Kohtaro Sonoda; Minoru Sugawara; Kenji Tatsuno; Y Totoki; Shuichi Tsutsumi; Hiroki Ueda; Hiroyuki Aburatani
Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency.
Genome research 2012;22(2):208-19.
2012: Shinya Akatsuka; Eri Arai; Okio Hino; Masashi Izumiya; Li Jiang; Yae Kanai; Yu-Ting Liu; Hideki Murakami; Hirotaka Nagai; Hitoshi Nakagama; Masako Ochiai; Hiroki Ohara; Yasumasa Okazaki; Yoshitaka Sekido; Takashi Takahashi; Koichiro Abe; Yoriko Yamashita; Shinya Toyokuni
Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer.
PloS one 2012;7(8):e43403.
2012: Hiroe Ono; Fumiko Chiwaki; Il Ju Choi; Nobuyoshi Hiraoka; Yae Kanai; Woo Jin Lee; Yeon-Su Lee; Sumiko Ohnami; Akira Saito; Hiromi Sakamoto; Hiroki Sasaki; Sang Myung Woo; Kazuyoshi Yanagihara; Teruhiko Yoshida; Norihisa Saeki
Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis.
Genes, chromosomes & cancer 2012;51(1):30-41.
2011: Takuma Hayashi; Nobuyoshi Hiraoka; Akiko Horiuchi; Tomoyuki Ichimura; Osamu Ishiko; Yae Kanai; Mari Kasai; Satoru Nagase; Kenji Sano; Tanri Shiozawa; Susumu Tonegawa; Nobuo Yaegashi; Hiroyuki Aburatani; Ikuo Konishi
Involvement of proteasome β1i subunit, LMP2, on development of uterin leiomyosarcma.
North American journal of medical sciences 2011;3(9):394-9.
2011: Shigeki Sekine; Reiko Ogawa; Hidenori Ojima; Yae Kanai
Expression of SLCO1B3 is associated with intratumoral cholestasis and CTNNB1 mutations in hepatocellular carcinoma.
Cancer science 2011;102(9):1742-7.
2011: Ryo Nagashio; Hidenori Ojima; Eri Arai; Yutaka Kondo; Tomoo Kosuge; Yae Kanai
Carcinogenetic risk estimation based on quantification of DNA methylation levels in liver tissue at the precancerous stage.
International journal of cancer. Journal international du cancer 2011;129(5):1170-9.
2011: Shigeki Sekine; Reiko Ogawa; Hidenori Ojima; Yae Kanai
Overexpression of α-methylacyl-CoA racemase is associated with CTNNB1 mutations in hepatocellular carcinomas.
Histopathology 2011;58(5):712-9.
2011: Shigeki Sekine; Reiko Ogawa; Yae Kanai
Hepatomas with activating Ctnnb1 mutations in 'Ctnnb1-deficient' livers: a tricky aspect of a conditional knockout mouse model.
Carcinogenesis 2011;32(4):622-8.
2011: Naotaka Nishiyama; Eri Arai; Ryo Nagashio; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Taiji Tsukamoto; Sana Yokoi; Issei Imoto; Johji Inazawa; Yae Kanai
Copy number alterations in urothelial carcinomas: their clinicopathological significance and correlation with DNA methylation alterations.
Carcinogenesis 2011;32(4):462-9.
2011: Akira Yokomizo; Tomohiro Sakuma; Michiko Takakura; Tesshi Yamada; Kazufumi Honda; Yae Kanai; Junichi Matsubara; Seiji Naito; Masaya Ono
Use of quantitative shotgun proteomics to identify fibronectin 1 as a potential plasma biomarker for clear cell carcinoma of the kidney.
Cancer biomarkers : section A of Disease markers 2011;10(3-4):175-83.
2011: Takuma Hayashi; Nobuyoshi Hiraoka; Akiko Horiuchi; Tomoyuki Ichimura; Osamu Ishiko; Yae Kanai; Mari Kasai; Ryuichiro Nishimura; Kenji Sano; Tanri Shiozawa; Tamotsu Sudo; Yoh-Ichi Tagawa; Nobuo Yaegashi; Hiroyuki Aburatani; Ikuo Konishi
Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy.
Scientific reports 2011;1():180.
2011: Eri Arai; Saori Wakai-Ushijima; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Sana Yokoi; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genome-wide DNA methylation profiles in renal tumors of various histological subtypes and non-tumorous renal tissues.
Pathobiology : journal of immunopathology, molecular and cellular biology 2011;78(1):1-9.
2011: Takuma Hayashi; Akiko Horiuchi; Kenji Sano; Nobuyoshi Hiraoka; Yae Kanai; Tanri Shiozawa; Susumu Tonegawa; Ikuo Konishi
Molecular Approach to Uterine Leiomyosarcoma: LMP2-Deficient Mice as an Animal Model of Spontaneous Uterine Leiomyosarcoma.
Sarcoma 2011;2011():476498.
2011: Masahiro Gotoh; Eri Arai; Saori Wakai-Ushijima; Nobuyoshi Hiraoka; Tomoo Kosuge; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Sana Yokoi; Issei Imoto; Johji Inazawa; Yae Kanai
Diagnosis and prognostication of ductal adenocarcinomas of the pancreas based on genome-wide DNA methylation profiling by bacterial artificial chromosome array-based methylated CpG island amplification.
Journal of biomedicine & biotechnology 2011;2011():780836.
2011: Nobuyoshi Hiraoka; Rie Yamazaki-Itoh; Yoshinori Ino; Yasunori Mizuguchi; Tesshi Yamada; Setsuo Hirohashi; Yae Kanai
CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in early intraepithelial stages of human pancreatic carcinogenesis.
Gastroenterology 2011;140(1):310-21.
2010: Shutaro Hori; Satoshi Nara; Kazuaki Shimada; Hidenori Ojima; Yae Kanai; Nobuyoshi Hiraoka
Serous cystic neoplasm in an intrapancreatic accessory spleen.
Pathology international 2010;60(10):681-4.
2010: Takashi Kohno; Ryutaro Kakinuma; Motoki Iwasaki; Taiki Yamaji; Hideo Kunitoh; Kenji Suzuki; Yoko Shimada; Kouya Shiraishi; Yoshio Kasuga; Gerson Shigeaki Hamada; Koh Furuta; Koji Tsuta; Hiromi Sakamoto; Aya Kuchiba; Seiichiro Yamamoto; Yae Kanai; Shoichiro Tsugane; Jun Yokota
Association of CYP19A1 polymorphisms with risks for atypical adenomatous hyperplasia and bronchioloalveolar carcinoma in the lungs.
Carcinogenesis 2010;31(10):1794-9.
2010: Nobuyoshi Hiraoka; Yoshinori Ino; Shigeki Sekine; Hitoshi Tsuda; K Shimada; Tomoo Kosuge; J Zavada; M Yoshida; K Yamada; T Koyama; Yae Kanai
Tumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation.
British journal of cancer 2010;103(7):1057-65.
2010: Takuya Matsumoto; Hidenori Ojima; Yuri Akishima-Fukasawa; Nobuyoshi Hiraoka; Hiroaki Onaya; Kazuaki Shimada; Yasunori Mizuguchi; Shintaro Sakurai; Toshiharu Ishii; Tomoo Kosuge; Yae Kanai
Solitary hepatic lymphangioma: report of a case.
Surgery today 2010;40(9):883-9.
2010: Takuma Hayashi; Akiko Horiuchi; Kenji Sano; Nobuyoshi Hiraoka; Yae Kanai; Tanri Shiozawa; Susumu Tonegawa; Ikuo Konishi
Mice-lacking LMP2, immuno-proteasome subunit, as an animal model of spontaneous uterine leiomyosarcoma.
Protein & cell 2010;1(8):711-7.
2010: Yuri Akishima-Fukasawa; Yoshinori Ino; Yukihiro Nakanishi; Ayaka Miura; Yoshihiro Moriya; Tadashi Kondo; Yae Kanai; Setsuo Hirohashi
Significance of PGP9.5 expression in cancer-associated fibroblasts for prognosis of colorectal carcinoma.
American journal of clinical pathology 2010;134(1):71-9.
2010: Daisuke Ban; Kazuaki Shimada; Shigeki Sekine; Yoshihiro Sakamoto; Tomoo Kosuge; Yae Kanai; Nobuyoshi Hiraoka
Pancreatic ducts as an important route of tumor extension for acinar cell carcinoma of the pancreas.
The American journal of surgical pathology 2010;34(7):1025-36.
2010: Nao Okada; Takahiro Hasebe; Motoki Iwasaki; Nobuko Tamura; Sadako Akashi-Tanaka; Takashi Hojo; Tatsuhiro Shibata; Yuko Sasajima; Yae Kanai; Takayuki Kinoshita
Metaplastic carcinoma of the breast.
Human pathology 2010;41(7):960-70.
2010: Yuri Miyazawa; Takamasa Uekita; Nobuyoshi Hiraoka; Satoko Fujii; Tomoo Kosuge; Yae Kanai; Yoshihisa Nojima; Ryuichi Sakai
CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation.
Cancer research 2010;70(12):5136-46.
2010: Eri Arai; Yae Kanai
DNA methylation profiles in precancerous tissue and cancers: carcinogenetic risk estimation and prognostication based on DNA methylation status.
Epigenomics 2010;2(3):467-81.
2010: Reiko Satow; Miki Shitashige; Yae Kanai; Fumitaka Takeshita; Hidenori Ojima; Takafumi Jigami; Kazufumi Honda; Tomoo Kosuge; Takahiro Ochiya; Setsuo Hirohashi; Tesshi Yamada
Combined functional genome survey of therapeutic targets for hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(9):2518-28.
2010: Hidenori Ojima; Daitaro Yoshikawa; Yoshihiro Ino; Hiroko Shimizu; Masashi Miyamoto; Akiko Kokubu; Nobuyoshi Hiraoka; Noriaki Morofuji; Tadashi Kondo; Hiroaki Onaya; Takuji Okusaka; Kazuaki Shimada; Yoshihiro Sakamoto; Minoru Esaki; Satoshi Nara; Tomoo Kosuge; Setsuo Hirohashi; Yae Kanai; Tatsuhiro Shibata
Establishment of six new human biliary tract carcinoma cell lines and identification of MAGEH1 as a candidate biomarker for predicting the efficacy of gemcitabine treatment.
Cancer science 2010;101(4):882-8.
2010: Jun Okamura; Shigeki Sekine; Satoshi Nara; Hidenori Ojima; Kazuaki Shimada; Yae Kanai; Nobuyoshi Hiraoka
Intraductal carcinosarcoma with a heterologous mesenchymal component originating in intraductal papillary-mucinous carcinoma (IPMC) of the pancreas with both carcinoma and osteosarcoma cells arising from IPMC cells.
Journal of clinical pathology 2010;63(3):266-9.
2010: Yusuke Yamamoto; Hidenori Ojima; Kazuaki Shimada; Hiroaki Onaya; Nobuyoshi Hiraoka; Yasunori Mizuguchi; Tomoo Kosuge; Yae Kanai
Long-term recurrence-free survival in a patient with primary hepatic carcinosarcoma: case report with a literature review.
Japanese journal of clinical oncology 2010;40(2):166-73.
2010: Eri Arai; Yae Kanai
Genetic and epigenetic alterations during renal carcinogenesis.
International journal of clinical and experimental pathology 2010;4(1):58-73.
2010: Yae Kanai
Genome-wide DNA methylation profiles in precancerous conditions and cancers.
Cancer science 2010;101(1):36-45.
2010: Makito Miyake; Kokichi Sugano; Hitomi Sugino; Kazuho Imai; Eri Matsumoto; Koshi Maeda; Shinich Fukuzono; Hiroki Ichikawa; Kiyotaka Kawashima; Kaoru Hirabayashi; Tetsuro Kodama; Hiroyuki Fujimoto; Tadao Kakizoe; Yae Kanai; Kiyohide Fujimoto; Yoshihiko Hirao
Fibroblast growth factor receptor 3 mutation in voided urine is a useful diagnostic marker and significant indicator of tumor recurrence in non-muscle invasive bladder cancer.
Cancer science 2010;101(1):250-8.
2010: Naotaka Nishiyama; Eri Arai; Yoshitomo Chihara; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Taiji Tsukamoto; Sana Yokoi; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genome-wide DNA methylation profiles in urothelial carcinomas and urothelia at the precancerous stage.
Cancer science 2010;101(1):231-40.
2009: Eri Arai; Saori Ushijima; Masahiro Gotoh; Hidenori Ojima; Tomoo Kosuge; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Sana Yokoi; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2009;125(12):2854-62.
2009: Yusuke Yamamoto; Nobuyoshi Kosaka; Minoru Tanaka; Fumiaki Koizumi; Yae Kanai; Takayuki Mizutani; Yoshiki Murakami; Masahiko Kuroda; Atsushi Miyajima; Takashi Kato; Takahiro Ochiya
MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2009;14(7):529-38.
2009: Shigeki Sekine; Reiko Ogawa; Michael McManus; Yae Kanai; Matthias Hebrok
Dicer is required for proper liver zonation.
The Journal of pathology 2009;219(3):365-72.
2009: Tohru Nakagawa; Yae Kanai; Motokiyo Komiyama; Hiroyuki Fujimoto; Tadao Kakizoe
Characteristics of prostate cancers found in specimens removed by radical cystoprostatectomy for bladder cancer and their relationship with serum prostate-specific antigen level.
Cancer science 2009;100(10):1880-4.
2009: Ayako Negishi; Mari Masuda; Masaya Ono; Kazufumi Honda; Miki Shitashige; Reiko Satow; Tomohiro Sakuma; Hideya Kuwabara; Yukihiro Nakanishi; Yae Kanai; Ken Omura; Setsuo Hirohashi; Tesshi Yamada
Quantitative proteomics using formalin-fixed paraffin-embedded tissues of oral squamous cell carcinoma.
Cancer science 2009;100(9):1605-11.
2009: Yuri Akishima-Fukasawa; Yukihiro Nakanishi; Yoshinori Ino; Yoshihiro Moriya; Yae Kanai; Setsuo Hirohashi
Prognostic significance of CXCL12 expression in patients with colorectal carcinoma.
American journal of clinical pathology 2009;132(2):202-10; quiz 307.
2009: Shigeki Sekine; Reiko Ogawa; Rie Ito; Nobuyoshi Hiraoka; Michael McManus; Yae Kanai; Matthias Hebrok
Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis.
Gastroenterology 2009;136(7):2304-2315.e1-4.
2009: Shigeki Sekine; Yukihiro Nakanishi; Reiko Ogawa; Satoko Kouda; Yae Kanai
Esophageal melanomas harbor frequent NRAS mutations unlike melanomas of other mucosal sites.
Virchows Archiv : an international journal of pathology 2009;454(5):513-7.
2009: Eri Arai; Saori Ushijima; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Sana Yokoi; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genome-wide DNA methylation profiles in both precancerous conditions and clear cell renal cell carcinomas are correlated with malignant potential and patient outcome.
Carcinogenesis 2009;30(2):214-21.
2009: Takahiro Yamanashi; Yukihiro Nakanishi; Gen Fujii; Yuri Akishima-Fukasawa; Yoshihiro Moriya; Yae Kanai; Masahiko Watanabe; Setsuo Hirohashi
Podoplanin expression identified in stromal fibroblasts as a favorable prognostic marker in patients with colorectal carcinoma.
Oncology 2009;77(1):53-62.
2009: Hidenori Ojima; Yae Kanai; Motoki Iwasaki; Nobuyoshi Hiraoka; Kazuaki Shimada; Tsuyoshi Sano; Yoshihiro Sakamoto; Minoru Esaki; Tomoo Kosuge; Michiie Sakamoto; Setsuo Hirohashi
Intraductal carcinoma component as a favorable prognostic factor in biliary tract carcinoma.
Cancer science 2009;100(1):62-70.
2008: Yae Kanai
Alterations of DNA methylation and clinicopathological diversity of human cancers.
Pathology international 2008;58(9):544-58.
2008: Eri Arai; Saori Ushijima; Hitoshi Tsuda; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genetic clustering of clear cell renal cell carcinoma based on array-comparative genomic hybridization: its association with DNA methylation alteration and patient outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(17):5531-9.
2008: Ryoko Kikuchi; Hitoshi Tsuda; Ken-ichi Kozaki; Yae Kanai; Takahiro Kasamatsu; Kazuo Sengoku; Setsuo Hirohashi; Johji Inazawa; Issei Imoto
Frequent inactivation of a putative tumor suppressor, angiopoietin-like protein 2, in ovarian cancer.
Cancer research 2008;68(13):5067-75.
2008: Takamasa Uekita; Masamitsu Tanaka; Misato Takigahira; Yuri Miyazawa; Yukihiro Nakanishi; Yae Kanai; Kazuyoshi Yanagihara; Ryuichi Sakai
CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma.
The American journal of pathology 2008;172(6):1729-39.
2008: Yae Kanai
Overexpression of HDACs: a prognostic marker for gastric cancer identified by tissue microarray.
The lancet oncology 2008;9(2):91-3.
2008: Satoshi Nara; Kazuaki Shimada; Tomoo Kosuge; Yae Kanai; Nobuyoshi Hiraoka
Minimally invasive intraductal papillary-mucinous carcinoma of the pancreas: clinicopathologic study of 104 intraductal papillary-mucinous neoplasms.
The American journal of surgical pathology 2008;32(2):243-55.
2008: Takuma Hayashi; Yuto Shimamura; Taro Saegusa; Akiko Horiuchi; Yukihiro Kobayashi; Nobuyoshi Hiraoka; Yae Kanai; Hiroyuki Aburatani; Kenji Sano; Ikuo Konishi
Molecular mechanisms of uterine leiomyosarcomas: involvement of defect in LMP2 expression.
Gene regulation and systems biology 2008;2():297-305.
2008: Hiroki Ochiai; Yukihiro Nakanishi; Yuri Fukasawa; Yasunori Sato; Kimio Yoshimura; Yoshihiro Moriya; Yae Kanai; Masahiko Watanabe; Hirotoshi Hasegawa; Yuko Kitagawa; Masaki Kitajima; Setsuo Hirohashi
A new formula for predicting liver metastasis in patients with colorectal cancer: immunohistochemical analysis of a large series of 439 surgically resected cases.
Oncology 2008;75(1-2):32-41.
2007: Yukihiro Yoshida; Akiko Kokubu; Kenji Suzuki; Hidehiko Kuribayashi; Koji Tsuta; Yoshihiro Matsuno; Masahiko Kusumoto; Yae Kanai; Hisao Asamura; Setsuo Hirohashi; Tatsuhiro Shibata
Molecular markers and changes of computed tomography appearance in lung adenocarcinoma with ground-glass opacity.
Japanese journal of clinical oncology 2007;37(12):907-12.
2007: Yuji Ishibashi; Hidenori Ojima; Nobuyoshi Hiraoka; Tsuyoshi Sano; Tomoo Kosuge; Yae Kanai
Invasive biliary cystic tumor without ovarian-like stroma.
Pathology international 2007;57(12):794-8.
2007: Yae Kanai; Setsuo Hirohashi
Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state.
Carcinogenesis 2007;28(12):2434-42.
2007: Makito Miyake; Kokichi Sugano; Kiyotaka Kawashima; Hiroki Ichikawa; Kaoru Hirabayashi; Tetsuro Kodama; Hiroyuki Fujimoto; Tadao Kakizoe; Yae Kanai; Kiyohide Fujimoto; Yoshihiko Hirao
Sensitive detection of FGFR3 mutations in bladder cancer and urine sediments by peptide nucleic acid-mediated real-time PCR clamping.
Biochemical and biophysical research communications 2007;362(4):865-71.
2007: Ryoko Kikuchi; Hitoshi Tsuda; Yae Kanai; Takahiro Kasamatsu; Kazuo Sengoku; Setsuo Hirohashi; Johji Inazawa; Issei Imoto
Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer.
Cancer research 2007;67(15):7095-105.
2007: Morio Sawada; Yae Kanai; Eri Arai; Saori Ushijima; Hidenori Ojima; Setsuo Hirohashi
Increased expression of DNA methyltransferase 1 (DNMT1) protein in uterine cervix squamous cell carcinoma and its precursor lesion.
Cancer letters 2007;251(2):211-9.
2007: Panayiotis Loukopoulos; Tatsuhiro Shibata; Hiroto Katoh; Akiko Kokubu; Michiie Sakamoto; Ken Yamazaki; Tomoo Kosuge; Yae Kanai; Fumie Hosoda; Issei Imoto; Misao Ohki; Johji Inazawa; Setsuo Hirohashi
Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome.
Cancer science 2007;98(3):392-400.
2007: Noritoshi Kobayashi; Nobuyoshi Hiraoka; Wataru Yamagami; Hidenori Ojima; Yae Kanai; Tomoo Kosuge; Atsushi Nakajima; Setsuo Hirohashi
FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(3):902-11.
2007: Yu Takahashi; Yuri Akishima-Fukasawa; Noritoshi Kobayashi; Tsuyoshi Sano; Tomoo Kosuge; Yuji Nimura; Yae Kanai; Nobuyoshi Hiraoka
Prognostic value of tumor architecture, tumor-associated vascular characteristics, and expression of angiogenic molecules in pancreatic endocrine tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):187-96.
2006: Tohru Nakagawa; Nobuyoshi Hiraoka; Fumie Ihara; Motokiyo Komiyama; Yae Kanai; Yoshihiro Matsuno
Primary adenocarcinoma of the rete testis with preceding diagnosis of pulmonary metastases.
International journal of urology : official journal of the Japanese Urological Association 2006;13(12):1532-5.
2006: Hiroto Katoh; Tatsuhiro Shibata; Akiko Kokubu; Hidenori Ojima; Tomoo Kosuge; Yae Kanai; Setsuo Hirohashi
Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: a case report.
Genes, chromosomes & cancer 2006;45(11):1050-7.
2006: Takebumi Usui; Kazuhiko Aoyagi; Norihisa Saeki; Yukihiro Nakanishi; Yae Kanai; Misao Ohki; Kenji Ogawa; Teruhiko Yoshida; Hiroki Sasaki
Expression status of RUNX1/AML1 in normal gastric epithelium and its mutational analysis in microdissected gastric cancer cells.
International journal of oncology 2006;29(4):779-84.
2006: Eri Arai; Yae Kanai; Saori Ushijima; Hiroyuki Fujimoto; Kiyoshi Mukai; Setsuo Hirohashi
Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues.
International journal of cancer. Journal international du cancer 2006;119(2):288-96.
2006: Dunfa Peng; Yae Kanai; Morio Sawada; Saori Ushijima; Nobuyoshi Hiraoka; Sohei Kitazawa; Setsuo Hirohashi
DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas.
Carcinogenesis 2006;27(6):1160-8.
2006: Tetsuo Maeda; Ukihide Tateishi; Hiroyuki Fujimoto; Yae Kanai; Kazuro Sugimura; Yasuaki Arai
Leiomyosarcoma of the renal vein: arterial encasement on contrast-enhanced dynamic computed tomography.
International journal of urology : official journal of the Japanese Urological Association 2006;13(5):611-2.
2006: Yu Takahashi; Nobuyoshi Hiraoka; Kaoru Onozato; Tatsuhiro Shibata; Tomoo Kosuge; Yuji Nimura; Yae Kanai; Setsuo Hirohashi
Solid-pseudopapillary neoplasms of the pancreas in men and women: do they differ?
Virchows Archiv : an international journal of pathology 2006;448(5):561-9.
2006: Hiroto Katoh; Tatsuhiro Shibata; Akiko Kokubu; Hidenori Ojima; Masashi Fukayama; Yae Kanai; Setsuo Hirohashi
Epigenetic instability and chromosomal instability in hepatocellular carcinoma.
The American journal of pathology 2006;168(4):1375-84.
2006: Daisuke Yamada; Shinji Kikuchi; Yuko N Williams; Mika Sakurai-Yageta; Mari Masuda; Tomoko Maruyama; Kyoichi Tomita; David H Gutmann; Tadao Kakizoe; Tadaichi Kitamura; Yae Kanai; Yoshinori Murakami
Promoter hypermethylation of the potential tumor suppressor DAL-1/4.1B gene in renal clear cell carcinoma.
International journal of cancer. Journal international du cancer 2006;118(4):916-23.
2005: Hiroto Katoh; Tatsuhiro Shibata; Akiko Kokubu; Hidenori Ojima; Panayiotis Loukopoulos; Yae Kanai; Tomoo Kosuge; Masashi Fukayama; Tadashi Kondo; Michiie Sakamoto; Fumie Hosoda; Misao Ohki; Issei Imoto; Johji Inazawa; Setsuo Hirohashi
Genetic profile of hepatocellular carcinoma revealed by array-based comparative genomic hybridization: identification of genetic indicators to predict patient outcome.
Journal of hepatology 2005;43(5):863-74.
2005: Wei-Xia Peng; Tatsuhiro Shibata; Hiroto Katoh; Akiko Kokubu; Yoshihiro Matsuno; Hisao Asamura; Ryosuke Tsuchiya; Yae Kanai; Fumie Hosoda; Tokuki Sakiyama; Misao Ohki; Issei Imoto; Johji Inazawa; Setsuo Hirohashi
Array-based comparative genomic hybridization analysis of high-grade neuroendocrine tumors of the lung.
Cancer science 2005;96(10):661-7.
2005: Yukihiro Yoshida; Tatsuhiro Shibata; Akiko Kokubu; Koji Tsuta; Yoshihiro Matsuno; Yae Kanai; Hisao Asamura; Ryosuke Tsuchiya; Setsuo Hirohashi
Mutations of the epidermal growth factor receptor gene in atypical adenomatous hyperplasia and bronchioloalveolar carcinoma of the lung.
Lung cancer (Amsterdam, Netherlands) 2005;50(1):1-8.
2005: Tatsuhiro Shibata; Satomi Uryu; Akiko Kokubu; Fumie Hosoda; Misao Ohki; Tokuki Sakiyama; Yoshihiro Matsuno; Ryosuke Tsuchiya; Yae Kanai; Tadashi Kondo; Issei Imoto; Johji Inazawa; Setsuo Hirohashi
Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(17):6177-85.
2005: Dunfa Peng; Yae Kanai; Morio Sawada; Saori Ushijima; Nobuyoshi Hiraoka; Tomoo Kosuge; Setsuo Hirohashi
Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas.
Cancer science 2005;96(7):403-8.
2005: Yoshitomo Chihara; Kokichi Sugano; Ayumi Kobayashi; Yae Kanai; Hidenobu Yamamoto; Masaaki Nakazono; Hiroyuki Fujimoto; Tadao Kakizoe; Kiyohide Fujimoto; Setsuo Hirohashi; Yoshihiko Hirao
Loss of blood group A antigen expression in bladder cancer caused by allelic loss and/or methylation of the ABO gene.
Laboratory investigation; a journal of technical methods and pathology 2005;85(7):895-907.
2005: Tohru Nakagawa; Yae Kanai; Saori Ushijima; Tadaichi Kitamura; Tadao Kakizoe; Setsuo Hirohashi
DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis.
The Journal of urology 2005;173(5):1767-71.
2005: Aya Nishizawa; Yukihiro Nakanishi; Kimio Yoshimura; Yuko Sasajima; Naoya Yamazaki; Akifumi Yamamoto; Katsumi Hanada; Yae Kanai; Setsuo Hirohashi
Clinicopathologic significance of dysadherin expression in cutaneous malignant melanoma: immunohistochemical analysis of 115 patients.
Cancer 2005;103(8):1693-700.
2005: Nobuhiro Nitori; Yoshinori Ino; Yukihiro Nakanishi; Tesshi Yamada; Kazufumi Honda; Kazuyoshi Yanagihara; Tomoo Kosuge; Yae Kanai; Masaki Kitajima; Setsuo Hirohashi
Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2531-9.
2005: Tohru Nakagawa; Yae Kanai; Saori Ushijima; Tadaichi Kitamura; Tadao Kakizoe; Setsuo Hirohashi
DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas.
The Journal of urology 2005;173(1):243-6.
2004: Shigeki Sekine; T Takata; Tatsuhiro Shibata; M Mori; Y Morishita; M Noguchi; T Uchida; Yae Kanai; Setsuo Hirohashi
Expression of enamel proteins and LEF1 in adamantinomatous craniopharyngioma: evidence for its odontogenic epithelial differentiation.
Histopathology 2004;45(6):573-9.
2004: Yukihiro Nakanishi; Shingo Akimoto; Yasuto Sato; Yae Kanai; Michiie Sakamoto; Setsuo Hirohashi
Prognostic significance of dysadherin expression in tongue cancer: immunohistochemical analysis of 91 cases.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2004;12(4):323-8.
2004: Yae Kanai; Yoshimasa Saito; Saori Ushijima; Setsuo Hirohashi
Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, during human hepatocarcinogenesis.
Journal of cancer research and clinical oncology 2004;130(11):636-44.
2004: Takeshi Shimamura; Jun Yasuda; Yoshinori Ino; Masahiro Gotoh; Akira Tsuchiya; Atsushi Nakajima; Michiie Sakamoto; Yae Kanai; Setsuo Hirohashi
Dysadherin expression facilitates cell motility and metastatic potential of human pancreatic cancer cells.
Cancer research 2004;64(19):6989-95.
2004: Shingo Akimoto; Yukihiro Nakanishi; Michiie Sakamoto; Yae Kanai; Setsuo Hirohashi
Laminin 5 beta3 and gamma2 chains are frequently coexpressed in cancer cells.
Pathology international 2004;54(9):688-92.
2004: Tatsuhiro Shibata; Akiko Kokubu; Shigeki Sekine; Yae Kanai; Setsuo Hirohashi
Cytoplasmic p120ctn regulates the invasive phenotypes of E-cadherin-deficient breast cancer.
The American journal of pathology 2004;164(6):2269-78.
2004: Tsuyoshi Etoh; Yae Kanai; Saori Ushijima; Tohru Nakagawa; Yukihiro Nakanishi; Mitsuru Sasako; Seigo Kitano; Setsuo Hirohashi
Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.
The American journal of pathology 2004;164(2):689-99.
2004: Jeong-Seok Nam; Yoshinori Ino; Yae Kanai; Michiie Sakamoto; Setsuo Hirohashi
5-aza-2'-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis.
Clinical & experimental metastasis 2004;21(1):49-56.
2003: Tohru Nakagawa; Yae Kanai; Yoshimasa Saito; Tadaichi Kitamura; Tadao Kakizoe; Setsuo Hirohashi
Increased DNA methyltransferase 1 protein expression in human transitional cell carcinoma of the bladder.
The Journal of urology 2003;170(6 Pt 1):2463-6.
2003: Shigeki Sekine; Sunao Sato; Takashi Takata; Yasuo Fukuda; Takeshi Ishida; Mitsunobu Kishino; Tatsuhiro Shibata; Yae Kanai; Setsuo Hirohashi
Beta-catenin mutations are frequent in calcifying odontogenic cysts, but rare in ameloblastomas.
The American journal of pathology 2003;163(5):1707-12.
2003: Shunsuke Ohnishi; Shumpei Ohnami; Friedrich Laub; Kazunori Aoki; Koichi Suzuki; Yae Kanai; Kazunori Haga; Masahiro Asaka; Francesco Ramirez; Teruhiko Yoshida
Downregulation and growth inhibitory effect of epithelial-type Krüppel-like transcription factor KLF4, but not KLF5, in bladder cancer.
Biochemical and biophysical research communications 2003;308(2):251-6.
2003: Setsuo Hirohashi; Yae Kanai
Cell adhesion system and human cancer morphogenesis.
Cancer science 2003;94(7):575-81.
2003: Yoshimasa Saito; Yae Kanai; Tohru Nakagawa; Michiie Sakamoto; Hidetsugu Saito; Hiromasa Ishii; Setsuo Hirohashi
Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.
International journal of cancer. Journal international du cancer 2003;105(4):527-32.
2003: Yohei Horikawa; Kokichi Sugano; Masanori Shigyo; Hidenobu Yamamoto; Masaaki Nakazono; Hiroyuki Fujimoto; Yae Kanai; Setsuo Hirohashi; Tadao Kakizoe; Tomonori Habuchi; Tetsuro Kato
Hypermethylation of an E-cadherin (CDH1) promoter region in high grade transitional cell carcinoma of the bladder comprising carcinoma in situ.
The Journal of urology 2003;169(4):1541-5.
2003: Yae Kanai; Saori Ushijima; Yukihiro Nakanishi; Michiie Sakamoto; Setsuo Hirohashi
Mutation of the DNA methyltransferase (DNMT) 1 gene in human colorectal cancers.
Cancer letters 2003;192(1):75-82.
2003: Ken Yamazaki; Michiie Sakamoto; Tsutomu Ohta; Yae Kanai; Misao Ohki; Setsuo Hirohashi
Overexpression of KIT in chromophobe renal cell carcinoma.
Oncogene 2003;22(6):847-52.
2002: Hitoshi Tsuda; Teruko Takarabe; Yae Kanai; Takashi Fukutomi; Setsuo Hirohashi
Correlation of DNA hypomethylation at pericentromeric heterochromatin regions of chromosomes 16 and 1 with histological features and chromosomal abnormalities of human breast carcinomas.
The American journal of pathology 2002;161(3):859-66.
2002: Shinichi Yachida; Noriyoshi Fukushima; Yae Kanai; Satoshi Nimura; Kazuaki Shimada; Junji Yamamoto; Michiie Sakamoto
Pancreatic metastasis from renal cell carcinoma extending into the main pancreatic duct: a case report.
Japanese journal of clinical oncology 2002;32(8):315-7.
2002: Yoshimasa Saito; Yae Kanai; Michiie Sakamoto; Hidetsugu Saito; Hiromasa Ishii; Setsuo Hirohashi
Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10060-5.
2001: Yae Kanai; Saori Ushijima; Yoshimasa Saito; Yukihiro Nakanishi; Michiie Sakamoto; Setsuo Hirohashi
MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers.
Journal of cancer research and clinical oncology 2001;127(12):697-706.
2001: Yae Kanai
[DNA methylation].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 6():142-6.
2001: N Fukushima; Michiie Sakamoto; K Mukai; Yae Kanai; Kazuaki Shimada; Tomoo Kosuge; Setsuo Hirohashi
Intraductal papillary components in invasive ductal carcinoma of the pancreas are associated with long-term survival of patients.
Human pathology 2001;32(8):834-41.
2001: Yoshimasa Saito; Yae Kanai; Michiie Sakamoto; Hidetsugu Saito; Hiromasa Ishii; Setsuo Hirohashi
Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 2001;33(3):561-8.
2001: Yae Kanai; Saori Ushijima; Y Kondo; Yukihiro Nakanishi; Setsuo Hirohashi
DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.
International journal of cancer. Journal international du cancer 2001;91(2):205-12.
2001: H Sato; T Hasegawa; Yae Kanai; Y Tsutsumi; Y Osamura; Y Abe; H Sakai; Setsuo Hirohashi
Expression of cadherins and their undercoat proteins (alpha-, beta-, and gamma-catenins and p120) and accumulation of beta-catenin with no gene mutations in synovial sarcoma.
Virchows Archiv : an international journal of pathology 2001;438(1):23-30.
2001: Tetsuo Kubota; N Watanabe; T Kaneko; F Satake; K Miura; Y Kurosawa; Nobuyuki Miyasaka; Yae Kanai
Activation of autoreactive T cells that help nucleobindin-injected mice produce anti-DNA antibodies.
Immunology letters 2001;75(2):111-5.
2000: X Zhu; Yae Kanai; A Saito; Y Kondo; Setsuo Hirohashi
Aberrant expression of beta-catenin and mutation of exon 3 of the beta-catenin gene in renal and urothelial carcinomas.
Pathology international 2000;50(12):945-52.
2000: Y Kondo; Yae Kanai; Michiie Sakamoto; M Mizokami; R Ueda; Setsuo Hirohashi
Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis--A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2000;32(5):970-9.
2000: F Satake; N Watanabe; Nobuyuki Miyasaka; Yae Kanai; Tetsuo Kubota
Induction of anti-DNA antibodies by immunization with anti-DNA antibodies: mechanism and characterization.
Lupus 2000;9(7):489-97.
2000: Yae Kanai; Saori Ushijima; Hitoshi Tsuda; Michiie Sakamoto; Setsuo Hirohashi
Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis.
Cancer letters 2000;148(1):73-80.
1999: K Ando; Y Matsuno; Yae Kanai; Michiie Sakamoto; H Fujimoto; M Narabayashi; K Tobisu
Primary low-grade lymphoma of mucosa-associated lymphoid tissue of the urinary bladder: a case report with special reference to the use of ancillary diagnostic studies.
Japanese journal of clinical oncology 1999;29(12):636-9.
1999: Y Kondo; Yae Kanai; Michiie Sakamoto; Takuya Genda; M Mizokami; R Ueda; Setsuo Hirohashi
Beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma.
Japanese journal of cancer research : Gann 1999;90(12):1301-9.
1999: Yae Kanai; S Ushijima; Y Nakanishi; Setsuo Hirohashi
Reduced mRNA expression of the DNA demethylase, MBD2, in human colorectal and stomach cancers.
Biochemical and biophysical research communications 1999;264(3):962-6.
1999: Fumiaki Masui; Yoshihiro Matsuno; R Yokoyama; Y Nakanishi; T Hasegawa; Yae Kanai; Yasuo Beppu; Setsuo Hirohashi; K Fujii; T Shimoda
Synovial sarcoma, histologically mimicking primitive neuroectodermal tumor/Ewing's sarcoma at distant sites.
Japanese journal of clinical oncology 1999;29(9):438-41.
1999: A Saito; Yae Kanai; C Maesawa; A Ochiai; A Torii; Setsuo Hirohashi
Disruption of E-cadherin-mediated cell adhesion systems in gastric cancers in young patients.
Japanese journal of cancer research : Gann 1999;90(9):993-9.
1999: Y Kondo; Yae Kanai; Michiie Sakamoto; M Mizokami; R Ueda; Setsuo Hirohashi
Microsatellite instability associated with hepatocarcinogenesis.
Journal of hepatology 1999;31(3):529-36.
1999: T Harabayashi; Yae Kanai; Tesshi Yamada; M Sakamoto; A Ochiai; Tadao Kakizoe; T Koyanagi; Setsuo Hirohashi
Reduction of integrin beta4 and enhanced migration on laminin in association with intraepithelial spreading of urinary bladder carcinomas.
The Journal of urology 1999;161(4):1364-71.
1999: Yae Kanai; AM Hui; L Sun; Saori Ushijima; Michiie Sakamoto; Hitoshi Tsuda; Setsuo Hirohashi
DNA hypermethylation at the D17S5 locus and reduced HIC-1 mRNA expression are associated with hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 1999;29(3):703-9.
1998: A S Takaoka; Tesshi Yamada; M Gotoh; Yae Kanai; K Imai; Setsuo Hirohashi
Cloning and characterization of the human beta4-integrin gene promoter and enhancers.
The Journal of biological chemistry 1998;273(50):33848-55.
1998: AM Hui; L Sun; Yae Kanai; Michiie Sakamoto; Setsuo Hirohashi
Reduced p27Kip1 expression in hepatocellular carcinomas.
Cancer letters 1998;132(1-2):67-73.
1998: Yae Kanai; Saori Ushijima; Atsushi Ochiai; K Eguchi; A Hui; Setsuo Hirohashi
DNA hypermethylation at the D17S5 locus is associated with gastric carcinogenesis.
Cancer letters 1998;122(1-2):135-41.
1998: Tetsuo Kubota; M Miyauchi; K Miura; Go Hirokawa; A Awaya; Nobuyuki Miyasaka; Y Kurosawa; Yae Kanai; K Maruyama
Upregulation of nucleobindin expression in human-activated lymphocytes and non-Hodgkin's lymphoma.
Pathology international 1998;48(1):22-8.
1997: L Sun; AM Hui; Yae Kanai; Michiie Sakamoto; Setsuo Hirohashi
Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis.
Japanese journal of cancer research : Gann 1997;88(12):1165-70.
1997: K Eguchi; Yae Kanai; K Kobayashi; Setsuo Hirohashi
DNA hypermethylation at the D17S5 locus in non-small cell lung cancers: its association with smoking history.
Cancer research 1997;57(21):4913-5.
1997: N Fukushima; K Mukai; Yae Kanai; Takahiro Hasebe; K Shimada; H Ozaki; Taira Kinoshita; Tomoo Kosuge
Intraductal papillary tumors and mucinous cystic tumors of the pancreas: clinicopathologic study of 38 cases.
Human pathology 1997;28(9):1010-7.
1997: Yae Kanai; Saori Ushijima; AM Hui; Atsushi Ochiai; Hitoshi Tsuda; Michiie Sakamoto; Setsuo Hirohashi
The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas.
International journal of cancer. Journal international du cancer 1997;71(3):355-9.
1997: AM Hui; Yae Kanai; Michiie Sakamoto; Hitoshi Tsuda; Setsuo Hirohashi
Reduced p21(WAF1/CIP1) expression and p53 mutation in hepatocellular carcinomas.
Hepatology (Baltimore, Md.) 1997;25(3):575-9.
1997: H Iizuka; Tetsuo Kubota; F Satake; Go Hirokawa; K Miura; Y Kurosawa; Nobuyuki Miyasaka; Yae Kanai
Enhanced expression of nucleobindin in lymphatic organs of lupus-prone mice.
Lupus 1997;6(4):365-70.
1996: Yae Kanai; Saori Ushijima; Hitoshi Tsuda; Michiie Sakamoto; T Sugimura; Setsuo Hirohashi
Aberrant DNA methylation on chromosome 16 is an early event in hepatocarcinogenesis.
Japanese journal of cancer research : Gann 1996;87(12):1210-7.
1996: AM Hui; Michiie Sakamoto; Yae Kanai; Y Ino; M Gotoh; J Yokota; Setsuo Hirohashi
Inactivation of p16INK4 in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 1996;24(3):575-9.
1996: H Muta; M Noguchi; Yae Kanai; Atsushi Ochiai; H Nawata; Setsuo Hirohashi
E-cadherin gene mutations in signet ring cell carcinoma of the stomach.
Japanese journal of cancer research : Gann 1996;87(8):843-8.
1995: Yae Kanai; Atsushi Ochiai; T Shibata; T Oyama; Saori Ushijima; S Akimoto; Setsuo Hirohashi
c-erbB-2 gene product directly associates with beta-catenin and plakoglobin.
Biochemical and biophysical research communications 1995;208(3):1067-72.
1994: T Oyama; Yae Kanai; Atsushi Ochiai; S Akimoto; T Oda; K Yanagihara; A Nagafuchi; S Tsukita; S Shibamoto; F Ito
A truncated beta-catenin disrupts the interaction between E-cadherin and alpha-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines.
Cancer research 1994;54(23):6282-7.
1994: Atsushi Ochiai; S Akimoto; Yae Kanai; T Shibata; T Oyama; Setsuo Hirohashi
c-erbB-2 gene product associates with catenins in human cancer cells.
Biochemical and biophysical research communications 1994;205(1):73-8.
1994: Yae Kanai; T Oda; Hitoshi Tsuda; Atsushi Ochiai; Setsuo Hirohashi
Point mutation of the E-cadherin gene in invasive lobular carcinoma of the breast.
Japanese journal of cancer research : Gann 1994;85(10):1035-9.
1994: Yae Kanai; T Oda; Y Shimoyama; Atsushi Ochiai; T Oyama; K Yoshiura; S Akimoto; T Yamada; Setsuo Hirohashi
Alterations of the cadherin-catenin cell adhesion system in cancers.
Princess Takamatsu symposia 1994;24():51-62.
1993: T Oda; Yae Kanai; Y Shimoyama; A Nagafuchi; S Tsukita; Setsuo Hirohashi
Cloning of the human alpha-catenin cDNA and its aberrant mRNA in a human cancer cell line.
Biochemical and biophysical research communications 1993;193(3):897-904.