Hideo Kanaide

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Maeda Yoshihisa; Hirano Katsuya; Hirano Mayumi; Kikkawa Yuichiro; Kameda Katsuharu; Sasaki Tomio; Kanaide Hideo
Enhanced contractile response of the basilar artery to platelet-derived growth factor in subarachnoid hemorrhage.
Kai Yasutoshi; Hirano Katsuya; Maeda Yoshihisa; Nishimura Junji; Sasaki Tomio; Kanaide Hideo
Prevention of the hypercontractile response to thrombin by proteinase-activated receptor-1 antagonist in subarachnoid hemorrhage.
Maeda Y; Hirano K; Kai Y; Hirano M; Suzuki S O; Sasaki T; Kanaide H
Up-regulation of proteinase-activated receptor 1 and increased contractile responses to thrombin after subarachnoid haemorrhage.

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2009: Maeda Yoshihisa; Hirano Katsuya; Hirano Mayumi; Kikkawa Yuichiro; Kameda Katsuharu; Sasaki Tomio; Kanaide Hideo
Enhanced contractile response of the basilar artery to platelet-derived growth factor in subarachnoid hemorrhage.
Stroke; a journal of cerebral circulation 2009;40(2):591-6.
2007: Kai Yasutoshi; Hirano Katsuya; Maeda Yoshihisa; Nishimura Junji; Sasaki Tomio; Kanaide Hideo
Prevention of the hypercontractile response to thrombin by proteinase-activated receptor-1 antagonist in subarachnoid hemorrhage.
Stroke; a journal of cerebral circulation 2007;38(12):3259-65.
2007: Maeda Y; Hirano K; Kai Y; Hirano M; Suzuki S O; Sasaki T; Kanaide H
Up-regulation of proteinase-activated receptor 1 and increased contractile responses to thrombin after subarachnoid haemorrhage.
British journal of pharmacology 2007;152(7):1131-9.
2007: Hirano Mayumi; Kanaide Hideo; Hirano Katsuya
Rac1-dependent transcriptional up-regulation of p27Kip1 by homophilic cell-cell contact in vascular endothelial cells.
Biochimica et biophysica acta 2007;1773(10):1500-10.
2007: Shiga K-i; Hirano K; Nishimura J; Niiro N; Naito S; Kanaide H
Dimethyl sulphoxide relaxes rabbit detrusor muscle by decreasing the Ca2+ sensitivity of the contractile apparatus.
British journal of pharmacology 2007;151(7):1014-24.
2007: Hirano Katsuya; Nomoto Namie; Hirano Mayumi; Momota Fumi; Hanada Akiko; Kanaide Hideo
Distinct Ca2+ requirement for NO production between proteinase-activated receptor 1 and 4 (PAR1 and PAR4) in vascular endothelial cells.
The Journal of pharmacology and experimental therapeutics 2007;322(2):668-77.
2007: Fujiyoshi Tetsuhiro; Hirano Katsuya; Hirano Mayumi; Nishimura Junji; Takahashi Shosuke; Kanaide Hideo
Plasmin induces endothelium-dependent nitric oxide-mediated relaxation in the porcine coronary artery.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):949-54.
2007: Karashima E; Nishimura J; Iwamoto T; Hirano K; Hirano M; Kita S; Harada M; Kanaide H
Involvement of Na+-Ca2+ exchanger in cAMP-mediated relaxation in mice aorta: evaluation using transgenic mice.
British journal of pharmacology 2007;150(4):434-44.
2007: Kanaide Hideo
[Regulation of the vascular smooth muscle tone--the Ca2+ signaling and the Ca2+ sensitivity of the contractile apparatus]
Fukuoka igaku zasshi = Hukuoka acta medica 2007;98(1):1-10.
2007: Takahashi Ryosuke; Nishimura Junji; Seki Narihito; Yunoki Takakazu; Tomoda Toshihisa; Kanaide Hideo; Naito Seiji
RhoA/Rho kinase-mediated Ca2+ sensitization in the contraction of human prostate.
Neurourology and urodynamics 2007;26(4):547-51.
2006: Hasegawa Yuhei; Nishimura Junji; Niiro Naohisa; Hirano Katsuya; Ishibashi Tatsuro; Kanaide Hideo
Prostaglandin F2alpha, but not latanoprost, increases the Ca2+ sensitivity of the pig iris sphincter muscle.
Investigative ophthalmology & visual science 2006;47(11):4865-71.
2006: Fukunaga Ryota; Hirano Katsuya; Hirano Mayumi; Niiro Naohisa; Nishimura Junji; Maehara Yoshihiko; Kanaide Hideo
Upregulation of proteinase-activated receptors and hypercontractile responses precede development of arterial lesions after balloon injury.
American journal of physiology. Heart and circulatory physiology 2006;291(5):H2388-95.
2006: Nishimura Junji; Bi Dan; Kanaide Hideo
Dependence of proliferating dedifferentiated vascular smooth muscle contraction on Rho-Rho kinase system.
Trends in cardiovascular medicine 2006;16(4):124-8.
2006: Momota Fumi; Hirano Katsuya; Hirano Mayumi; Nishimura Junji; Kanaide Hideo
Involvement of Gi/o in the PAR-4-induced NO production in endothelial cells.
Biochemical and biophysical research communications 2006;342(2):365-71.
2006: Kanaide Hideo
Measurement of [Ca2+]i in smooth muscle strips using front-surface fluorimetry.
Methods in molecular biology (Clifton, N.J.) 2006;312():251-9.
2005: Aman Murasaki; Hirano Katsuya; Nishimura Junji; Nakano Hitoo; Kanaide Hideo
Enhancement of trypsin-induced contraction by in vivo treatment with 17beta-estradiol and progesterone in rat myometrium.
British journal of pharmacology 2005;146(3):425-34.
2005: Takahashi Ryosuke; Nishimura Junji; Hirano Katsuya; Naito Seiji; Kanaide Hideo
Functional role of PKC in contraction of cultured human prostatic stromal cells.
Journal of cellular biochemistry 2005;96(1):65-78.
2005: Yufu Tatsuya; Hirano Katsuya; Bi Dan; Hirano Mayumi; Nishimura Junji; Iwamoto Yukihide; Kanaide Hideo
Rac1 regulation of surface expression of protease-activated receptor-1 and responsiveness to thrombin in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(7):1506-11.
2005: Kawata Hiroshi; Hirano Katsuya; Nishimura Junji; Kubo Chiharu; Kanaide Hideo
The mechanism underlying the contractile effect of a chemotactic peptide, formyl-Met-Leu-Phe on the guinea-pig Taenia coli.
British journal of pharmacology 2005;145(3):353-63.
2005: Shiga Noriko; Hirano Katsuya; Hirano Mayumi; Nishimura Junji; Nawata Hajime; Kanaide Hideo
Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery.
Circulation research 2005;96(9):1014-21.
2005: Bi Dan; Nishimura Junji; Niiro Naohisa; Hirano Katsuya; Kanaide Hideo
Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractility.
Circulation research 2005;96(8):890-7.
2005: Hirano Katsuya; Yufu Tatsuya; Hirano Mayumi; Nishimura Junji; Kanaide Hideo
Physiology and pathophysiology of proteinase-activated receptors (PARs): regulation of the expression of PARs.
Journal of pharmacological sciences 2005;97(1):31-7.
2004: Hirano Katsuya; Hirano Mayumi; Kanaide Hideo
Regulation of myosin phosphorylation and myofilament Ca2+ sensitivity in vascular smooth muscle.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 2004;40(6):219-36.
2004: Koga Miho; Hirano Katsuya; Hirano Mayumi; Nishimura Junji; Nakano Hitoo; Kanaide Hideo
Akt plays a central role in the anti-apoptotic effect of estrogen in endothelial cells.
Biochemical and biophysical research communications 2004;324(1):321-5.
2004: Hirano Katsuya; Ihara Eikichi; Hirano Mayumi; Nishimura Junji; Nawata Hajime; Kanaide Hideo
Facilitation of proteasomal degradation of p27Kip1 by N-terminal cleavage and their sequence requirements.
FEBS letters 2004;574(1-3):111-5.
2004: Takahashi Ryosuke; Nishimura Junji; Hirano Katsuya; Seki Narihito; Naito Seiji; Kanaide Hideo
Ca2+ sensitization in contraction of human bladder smooth muscle.
The Journal of urology 2004;172(2):748-52.
2004: Hirano Katsuya; Hirano Mayumi; Nishimura Junji; Kanaide Hideo
A critical period requiring Rho proteins for cell cycle progression uncovered by reversible protein transduction in endothelial cells.
FEBS letters 2004;570(1-3):149-54.
2004: Koga Miho; Hirano Katsuya; Nishimura Junji; Nakano Hitoo; Kanaide Hideo
Endothelium-dependent and independent enhancement of vascular contractility in the ovariectomized rabbit.
Journal of the Society for Gynecologic Investigation 2004;11(5):272-9.
2004: Nakayama Tetsuzo; Hirano Katsuya; Hirano Mayumi; Nishimura Junji; Kuga Hirotaka; Nakamura Katsuya; Takahashi Shosuke; Kanaide Hideo
Inactivation of protease-activated receptor-1 by proteolytic removal of the ligand region in vascular endothelial cells.
Biochemical pharmacology 2004;68(1):23-32.
2004: Maeda Yoshihisa; Hirano Katsuya; Nishimura Junji; Sasaki Tomio; Kanaide Hideo
Endothelial dysfunction and altered bradykinin response due to oxidative stress induced by serum deprivation in the bovine cerebral artery.
European journal of pharmacology 2004;491(1):53-60.
2004: Hirano Katsuya; Derkach Dmitry N; Hirano Mayumi; Nishimura Junji; Takahashi Shosuke; Kanaide Hideo
Transduction of the N-terminal fragments of MYPT1 enhances myofilament Ca2+ sensitivity in an intact coronary artery.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(3):464-9.
2003: Eto Wakako; Hirano Katsuya; Hirano Mayumi; Nishimura Junji; Kanaide Hideo
Intracellular alkalinization induces Ca2+ influx via non-voltage-operated Ca2+ channels in rat aortic smooth muscle cells.
Cell calcium 2003;34(6):477-84.
2003: Nishimura Junji; Kanaide Hideo
[Changes in the contractility of the NIH3T3 fibroblast induced by the over-expression of CPI-17]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 2003;122 Suppl():43P-45P.
2003: Kanaide Hideo; Ichiki Toshihiro; Nishimura Junji; Hirano Katsuya
Cellular mechanism of vasoconstriction induced by angiotensin II: it remains to be determined.
Circulation research 2003;93(11):1015-7.
2003: Maeda Yoshihisa; Hirano Katsuya; Nishimura Junji; Sasaki Tomio; Kanaide Hideo
Rho-kinase inhibitor inhibits both myosin phosphorylation-dependent and -independent enhancement of myofilament Ca2+ sensitivity in the bovine middle cerebral artery.
British journal of pharmacology 2003;140(5):871-80.
2003: Ise Shinji; Nishimura Junji; Hirano Katsuya; Hara Nobuyuki; Kanaide Hideo
Theophylline attenuates Ca2+ sensitivity and modulates BK channels in porcine tracheal smooth muscle.
British journal of pharmacology 2003;140(5):939-47.
2003: Hirano Katusya; Derkach Dmitry N; Hirano Mayumi; Nishimura Junji; Kanaide Hideo
Protein kinase network in the regulation of phosphorylation and dephosphorylation of smooth muscle myosin light chain.
Molecular and cellular biochemistry 2003;248(1-2):105-14.
2003: Takahashi Ryosuke; Nishimura Junji; Hirano Katsuya; Naito Seiji; Kanaide Hideo
Modulation of Ca2+ sensitivity regulates contractility of rabbit corpus cavernosum smooth muscle.
The Journal of urology 2003;169(6):2412-6.
2003: Beppu Kiichiro; Morisaki Takashi; Matsunaga Hisashi; Uchiyama Akihiko; Ihara Eikichi; Hirano Katsuya; Kanaide Hideo; Tanaka Masao; Katano Mitsuo
Inhibition of interferon-gamma-activated nuclear factor-kappa B by cyclosporin A: A possible mechanism for synergistic induction of apoptosis by interferon-gamma and cyclosporin A in gastric carcinoma cells.
Biochemical and biophysical research communications 2003;305(4):797-805.
2003: Yamanaka Jun; Nishimura Junji; Hirano Katsuya; Kanaide Hideo
An important role for the Na+-Ca2+ exchanger in the decrease in cytosolic Ca2+ concentration induced by isoprenaline in the porcine coronary artery.
The Journal of physiology 2003;549(Pt 2):553-62.
2003: Hirano Katsuya; Zeng Ying; Hirano Mayumi; Nishimura Junji; Kanaide Hideo
Sequence requirement for nuclear localization and growth inhibition of p27Kip1R, a degradation-resistant isoform of p27Kip1.
Journal of cellular biochemistry 2003;89(1):191-202.
2003: Fukuyama Kae; Ichiki Toshihiro; Takeda Kotaro; Tokunou Tomotake; Iino Naoko; Masuda Satoko; Ishibashi Minako; Egashira Kensuke; Shimokawa Hiroaki; Hirano Katsuya; Kanaide Hideo; Takeshita Akira
Downregulation of vascular angiotensin II type 1 receptor by thyroid hormone.
Hypertension 2003;41(3):598-603.
2003: Nakayama Tetsuzo; Hirano Katsuya; Shintani Yoshinobu; Nishimura Junji; Nakatsuka Akio; Kuga Hirotaka; Takahashi Shosuke; Kanaide Hideo
Unproductive cleavage and the inactivation of protease-activated receptor-1 by trypsin in vascular endothelial cells.
British journal of pharmacology 2003;138(1):121-30.
2003: Hirano Katsuya; Kanaide Hideo
Role of protease-activated receptors in the vascular system.
Journal of atherosclerosis and thrombosis 2003;10(4):211-25.
2002: Takahashi Ryosuke; Nishimura Junji; Hirano Katsuya; Naito Seiji; Kanaide Hideo
The mechanisms for tachykinin-induced contractions of the rabbit corpus cavernosum.
British journal of pharmacology 2002;137(6):845-54.
2002: Takahashi Ryosuke; Naito Seiji; Takahashi Ryosuke; Nishimura Junji; Kanaide Hideo
[The modulation of Ca2+ sensitivity regulates the contractility of the corpus cavernosum smooth muscle]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 6():57-61.
2002: Ihara Eikichi; Hirano Katsuya; Hirano Mayumi; Nishimura Junji; Nawata Hajime; Kanaide Hideo
Mechanism of down-regulation of L-type Ca(2+) channel in the proliferating smooth muscle cells of rat aorta.
Journal of cellular biochemistry 2002;87(2):242-51.
2001: Ichiki T; Takeda K; Tokunou T; Iino N; Egashira K; Shimokawa H; Hirano K; Kanaide H; Takeshita A
Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(12):1896-901.
2001: Hirano M; Hirano K; Nishimura J; Kanaide H
Transcriptional up-regulation of p27(Kip1) during contact-induced growth arrest in vascular endothelial cells.
Experimental cell research 2001;271(2):356-67.
2001: Nakayama T; Hirano K; Nishimura J; Takahashi S; Kanaide H
Mechanism of trypsin-induced endothelium-dependent vasorelaxation in the porcine coronary artery.
British journal of pharmacology 2001;134(4):815-26.
2001: Ohnishi Y; Hirano K; Nishimura J; Furue M; Kanaide H
Inhibitory effects of brefeldin A, a membrane transport blocker, on the bradykinin-induced hyperpolarization-mediated relaxation in the porcine coronary artery.
British journal of pharmacology 2001;134(1):168-78.
2001: Shintani Y; Hirano K; Nakayama T; Nishimura J; Nakano H; Kanaide H
Mechanism of trypsin-induced contraction in the rat myometrium: the possible involvement of a novel member of protease-activated receptor.
British journal of pharmacology 2001;133(8):1276-85.
2001: Ihara E; Derkach D N; Hirano K; Nishimura J; Nawata H; Kanaide H
Ca(2+) influx in the endothelial cells is required for the bradykinin-induced endothelium-dependent contraction in the porcine interlobar renal artery.
The Journal of physiology 2001;534(Pt 3):701-11.
2001: Nakamura K; Nishimura J; Hirano K; Ibayashi S; Fujishima M; Kanaide H
Hydroxyfasudil, an active metabolite of fasudil hydrochloride, relaxes the rabbit basilar artery by disinhibition of myosin light chain phosphatase.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(7):876-85.
2001: Ieiri S; Nishimura J; Hirano K; Suita S; Kanaide H
The mechanism for the contraction induced by leukotriene C4 in guinea-pig taenia coli.
British journal of pharmacology 2001;133(4):529-38.
2001: Nishimura J; Setoguchi H; Kanaide H
[Regulation of vascular tone by the modulation of Ca2+ sensitivity]
Clinical calcium 2001;11(4):411-7.
2001: Setoguchi H; Nishimura J; Hirano K; Takahashi S; Kanaide H
Leukotriene C(4) enhances the contraction of porcine tracheal smooth muscle through the activation of Y-27632, a rho kinase inhibitor, sensitive pathway.
British journal of pharmacology 2001;132(1):111-8.
2001: Hirano K; Hirano M; Zeng Y; Nishimura J; Hara K; Muta K; Nawata H; Kanaide H
Cloning and functional expression of a degradation-resistant novel isoform of p27Kip1.
The Biochemical journal 2001;353(Pt 1):51-57.
2000: Derkach D N; Ihara E; Hirano K; Nishimura J; Takahashi S; Kanaide H
Thrombin causes endothelium-dependent biphasic regulation of vascular tone in the porcine renal interlobar artery.
British journal of pharmacology 2000;131(8):1635-42.
2000: Shintani Y; Hirano K; Nishimura J; Nakano H; Kanaide H
Enhanced contractile response to thrombin in the pregnant rat myometrium.
British journal of pharmacology 2000;131(8):1619-28.
2000: Ieiri S; Hirano K; Nishimura J; Suita S; Kanaide H
Alteration of the [Ca(2+)](i)-force relationship during the vasorelaxation induced by a Ca(2+) channel blocker SR33805 in the porcine coronary artery.
British journal of pharmacology 2000;131(8):1597-606.
2000: Matoba T; Shimokawa H; Nakashima M; Hirakawa Y; Mukai Y; Hirano K; Kanaide H; Takeshita A
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice.
The Journal of clinical investigation 2000;106(12):1521-30.
2000: Takeda K; Ichiki T; Tokunou T; Funakoshi Y; Iino N; Hirano K; Kanaide H; Takeshita A
Peroxisome proliferator-activated receptor gamma activators downregulate angiotensin II type 1 receptor in vascular smooth muscle cells.
Circulation 2000;102(15):1834-9.
2000: Hirano K; Hirano M; Eto W; Nishimura J; Kanaide H
Mitogen-induced up-regulation of non-smooth muscle isoform of alpha-tropomyosin in rat aortic smooth muscle cells.
European journal of pharmacology 2000;406(2):209-18.
2000: Morisaki T; Matsunaga H; Beppu K; Ihara E; Hirano K; Kanaide H; Mori M; Katano M
A combination of cyclosporin-A (CsA) and interferon-gamma (INF-gamma) induces apoptosis in human gastric carcinoma cells.
Anticancer research 2000;20(5B):3363-73.
2000: Kuroiwa-Matsumoto M; Hirano K; Ahmed A; Kawasaki J; Nishimura J; Kanaide H
Mechanisms of the thapsigargin-induced Ca(2+) entry in in situ endothelial cells of the porcine aortic valve and the endothelium-dependent relaxation in the porcine coronary artery.
British journal of pharmacology 2000;131(1):115-23.
2000: Zeng Y; Hirano K; Hirano M; Nishimura J; Kanaide H
Minimal requirements for the nuclear localization of p27(Kip1), a cyclin-dependent kinase inhibitor.
Biochemical and biophysical research communications 2000;274(1):37-42.
2000: Shintani Y; Nishimura J; Niiro N; Hirano K; Nakano H; Kanaide H
Mechanisms underlying the neurokinin A-induced contraction of the pregnant rat myometrium.
British journal of pharmacology 2000;130(5):1165-73.
2000: Mizuno O; Kobayashi S; Hirano K; Nishimura J; Kubo C; Kanaide H
Stimulus-specific alteration of the relationship between cytosolic Ca(2+) transients and nitric oxide production in endothelial cells ex vivo.
British journal of pharmacology 2000;130(5):1140-6.
2000: Kawasaki J; Hirano K; Hirano M; Nishimura J; Nakatsuka A; Fujishima M; Kanaide H
Dissociation between the Ca(2+) signal and tube formation induced by vascular endothelial growth factor in bovine aortic endothelial cells.
European journal of pharmacology 2000;398(1):19-29.
2000: Ihara E; Hirano K; Derkach D N; Nishimura J; Nawata H; Kanaide H
The mechanism of bradykinin-induced endothelium-dependent contraction and relaxation in the porcine interlobar renal artery.
British journal of pharmacology 2000;129(5):943-52.
2000: Ushio-Fukai M; Yamamoto H; Nishimura J; Hirano K; Kanaide H
The mechanism of the decrease in cytosolic Ca2+ concentrations induced by angiotensin II in the high K(+)-depolarized rabbit femoral artery.
British journal of pharmacology 2000;129(3):437-47.
2000: Ushio-Fukai M; Yamamoto H; Toyofuku K; Nishimura J; Hirano K; Kanaide H
Changes in the cytosolic Ca2+ concentration and Ca(2+)-sensitivity of the contractile apparatus during angiotensin II-induced desensitization in the rabbit femoral artery.
British journal of pharmacology 2000;129(3):425-36.
2000: Mizuno O; Hirano K; Nishimura J; Kubo C; Kanaide H
Proteolysis and phosphorylation-mediated regulation of thrombin receptor activity in in situ endothelial cells.
European journal of pharmacology 2000;389(1):13-23.
1999: Ihara E; Hirano K; Nishimura J; Nawata H; Kanaide H
Thapsigargin-induced endothelium-dependent triphasic regulation of vascular tone in the porcine renal artery.
British journal of pharmacology 1999;128(3):689-99.
1999: Kawasaki J; Hirano K; Hirano M; Nishimura J; Fujishima M; Kanaide H
Troglitazone inhibits the capacitative Ca2+ entry in endothelial cells.
European journal of pharmacology 1999;373(1):111-20.
1999: Zhou Y; Hirano K; Sakihara C; Nishimura J; Kanaide H
NH2-terminal fragments of the 130 kDa subunit of myosin phosphatase increase the Ca2+ sensitivity of porcine renal artery.
The Journal of physiology 1999;516 ( Pt 1)():55-65.
1999: Yasutsune T; Kawakami N; Hirano K; Nishimura J; Yasui H; Kitamura K; Kanaide H
Vasorelaxation and inhibition of the voltage-operated Ca2+ channels by FK506 in the porcine coronary artery.
British journal of pharmacology 1999;126(3):717-29.
1999: Zhou Y; Nishimura J; Hirano K; Kanaide H
The exogenously added small subunit of smooth muscle myosin phosphatase increases the Ca2+ sensitivity of the contractile apparatus in the permeabilized porcine renal artery.
Biochemical and biophysical research communications 1999;254(1):158-63.
1999: Hirano M; Niiro N; Hirano K; Nishimura J; Hartshorne D J; Kanaide H
Expression, subcellular localization, and cloning of the 130-kDa regulatory subunit of myosin phosphatase in porcine aortic endothelial cells.
Biochemical and biophysical research communications 1999;254(2):490-6.
1999: Kanaide H
Measurement of [Ca2+]i in smooth muscle strips using front-surface fluorimetry.
Methods in molecular biology (Clifton, N.J.) 1999;114():269-77.
1998: Kawasaki J; Hirano K; Nishimura J; Fujishima M; Kanaide H
Mechanisms of vasorelaxation induced by troglitazone, a novel antidiabetic drug, in the porcine coronary artery.
Circulation 1998;98(22):2446-52.
1998: Niiro N; Nishimura J; Hirano K; Nakano H; Kanaide H
Mechanisms of galanin-induced contraction in the rat myometrium.
British journal of pharmacology 1998;124(8):1623-32.
1998: Mizuno O; Hirano K; Nishimura J; Kubo C; Kanaide H
Mechanism of endothelium-dependent relaxation induced by thrombin in the pig coronary artery.
European journal of pharmacology 1998;351(1):67-77.
1998: Seguchi H; Nishimura J; Zhou Y; Niiro N; Kumazawa J; Kanaide H
Expression of beta3-adrenoceptors in rat detrusor smooth muscle.
The Journal of urology 1998;159(6):2197-201.
1998: Ahmed A; Kobayashi S; Shikasho T; Nishimura J; Kanaide H
Differential effects of Ca2+ channel blockers on Ca2+ transients and cell cycle progression in vascular smooth muscle cells.
European journal of pharmacology 1998;344(2-3):323-31.
1998: Zhou Y; Nishimura J; Seguchi H; Hirano K; Kanaide H
Expression and function of alpha1-adrenoceptor subtypes in the porcine renal artery.
European journal of pharmacology 1998;341(1):95-103.
1997: Sumiyoshi R; Nishimura J; Kawasaki J; Kobayashi S; Takahashi S; Kanaide H
Diadenosine polyphosphates directly relax porcine coronary arterial smooth muscle.
The Journal of pharmacology and experimental therapeutics 1997;283(2):548-56.
1997: Yoshimura H; Nishimura J; Sakihara C; Kobayashi S; Takahashi S; Kanaide H
Expression and function of endothelins, endothelin receptors, and endothelin converting enzyme in the porcine trachea.
American journal of respiratory cell and molecular biology 1997;17(4):471-80.
1997: Eguchi D; Nishimura J; Kobayashi S; Komori K; Sugimachi K; Kanaide H
Down-regulation of endothelin B receptors in autogenous saphenous veins grafted into the arterial circulation.
Cardiovascular research 1997;35(2):360-7.
1997: Kawasaki J; Kobayashi S; Miyagi Y; Nishimura J; Fujishima M; Kanaide H
The mechanisms of the relaxation induced by vasoactive intestinal peptide in the porcine coronary artery.
British journal of pharmacology 1997;121(5):977-85.
1997: Chen X; Miyagi Y; Nishimura J; Kobayashi S; Fukui M; Kanaide H
Resting load and modulation of the myofilament Ca2+ sensitivity in rabbit cerebral arteries.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(2):236-40.
1997: Eguchi D; Nishimura J; Kobayashi S; Komori K; Sugimachi K; Kanaide H
Mechanism of contraction induced by bradykinin in the rabbit saphenous vein.
British journal of pharmacology 1997;120(3):371-8.
1997: Nishimura J; Seguchi H; Sakihara C; Kureishi Y; Yoshimura H; Kobayashi S; Kanaide H
The relaxant effect of adrenomedullin on particular smooth muscles despite a general expression of its mRNA in smooth muscle, endothelial and epithelial cells.
British journal of pharmacology 1997;120(2):193-200.
1997: Niiro N; Nishimura J; Sakihara C; Nakano H; Kanaide H
Up-regulation of rho A and rho-kinase mRNAs in the rat myometrium during pregnancy.
Biochemical and biophysical research communications 1997;230(2):356-9.
1996: Hiroishi G; Kobayashi S; Nishimura J; Inomata H; Kanaide H
Differential effects of diltiazem and nitroglycerin on cytosolic Ca2+ concentration and on force in the bovine ophthalmic artery.
Investigative ophthalmology & visual science 1996;37(13):2612-23.
1996: Kai T; Takahashi S; Kanaide H
Halothane counteracts acetylcholine-induced increase in Ca2+ sensitivity of the contractile apparatus in airway smooth muscle.
European journal of pharmacology 1996;315(3):313-8.
1996: Nishimura J; Sakihara C; Zhou Y; Kanaide H
Expression of rho A and rho kinase mRNAs in porcine vascular smooth muscle.
Biochemical and biophysical research communications 1996;227(3):750-4.
1996: Sakihara C; Nishimura J; Kobayashi S; Takahashi S; Kanaide H
Direct inhibitory effect of chlorpromazine on smooth muscle of the porcine pulmonary artery.
Anesthesiology 1996;85(3):616-25.
1996: Kuga T; Kobayashi S; Hirakawa Y; Kanaide H; Takeshita A
Cell cycle--dependent expression of L- and T-type Ca2+ currents in rat aortic smooth muscle cells in primary culture.
Circulation research 1996;79(1):14-9.
1996: Fukuizumi Y; Kobayashi S; Nishimura J; Kanaide H
The effects of calcitonin gene-related peptide on the cytosolic calcium concentration and force in the porcine coronary artery.
The Journal of pharmacology and experimental therapeutics 1996;278(1):220-31.
1996: Kanaide H
Endothelin regulation of vascular tonus.
General pharmacology 1996;27(4):559-63.
1996: Miyagi Y; Kobayashi S; Nishimura J; Fukui M; Kanaide H
Dual regulation of cerebrovascular tone by UTP: P2U receptor-mediated contraction and endothelium-dependent relaxation.
British journal of pharmacology 1996;118(4):847-56.
1996: Higuchi Y; Nishimura J; Kobayashi S; Kanaide H
CPA induces a sustained increase in [Ca2+]i of endothelial cells in situ and relaxes porcine coronary artery.
The American journal of physiology 1996;270(6 Pt 2):H2038-49.
1996: Seguchi H; Nishimura J; Toyofuku K; Kobayashi S; Kumazawa J; Kanaide H
The mechanism of relaxation induced by atrial natriuretic peptide in the porcine renal artery.
British journal of pharmacology 1996;118(2):343-51.
1996: Miyagi Y; Kobayashi S; Nishimura J; Fukui M; Kanaide H
P2U receptor is linked to cytosolic Ca2+ transient and release of vasorelaxing factor in bovine endothelial cells in situ.
The Journal of physiology 1996;492 ( Pt 3)():751-61.
1996: Miyagi Y; Kobayashi S; Ahmed A; Nishimura J; Fukui M; Kanaide H
P2U purinergic activation leads to the cell cycle progression from the G1 to the S and M phases but not from the G0 to G1 phase in vascular smooth muscle cells in primary culture.
Biochemical and biophysical research communications 1996;222(2):652-8.
1996: Sakihara C; Nishimura J; Kobayashi S; Takahashi S; Kanaide H
Expression of calponin mRNA in porcine aortic endothelial cells.
Biochemical and biophysical research communications 1996;222(2):195-200.
1996: Jahan H; Kobayashi S; Nishimura J; Kanaide H
Endothelin-1 and angiotensin II act as progression but not competence growth factors in vascular smooth muscle cells.
European journal of pharmacology 1996;295(2-3):261-9.
1995: Yoshimura H; Kai T; Nishimura J; Kobayashi S; Takahashi S; Kanaide H
Effects of midazolam on intracellular Ca2+ and tension in airway smooth muscles.
Anesthesiology 1995;83(5):1009-20.
1995: Kuroiwa M; Aoki H; Kobayashi S; Nishimura J; Kanaide H
Mechanism of endothelium-dependent relaxation induced by substance P in the coronary artery of the pig.
British journal of pharmacology 1995;116(3):2040-7.
1995: Seguchi H; Nishimura J; Kobayashi S; Kumazawa J; Kanaide H
Autocrine regulation of the renal arterial tone by adrenomedullin.
Biochemical and biophysical research communications 1995;215(2):619-25.
1995: Nishimura J; Aoki H; Chen X; Shikasho T; Kobayashi S; Kanaide H
Evidence for the presence of endothelin ETA receptors in endothelial cells in situ on the aortic side of porcine aortic valve.
British journal of pharmacology 1995;115(8):1369-76.
1995: Kureishi Y; Kobayashi S; Nishimura J; Nakano T; Kanaide H
Adrenomedullin decreases both cytosolic Ca2+ concentration and Ca(2+)-sensitivity in pig coronary arterial smooth muscle.
Biochemical and biophysical research communications 1995;212(2):572-9.
1995: Miyagi Y; Kobayashi S; Nishimura J; Fukui M; Kanaide H
Resting load regulates vascular sensitivity by a cytosolic Ca(2+)-insensitive mechanism.
The American journal of physiology 1995;268(6 Pt 1):C1332-41.
1995: Hiroishi G; Kobayashi S; Nishimura J; Inomata H; Kanaide H
High D-glucose stimulates the cell cycle from the G1 to the S and M phases, but has no competent effect on the G0 phase, in vascular smooth muscle cells.
Biochemical and biophysical research communications 1995;211(2):619-26.
1995: Toyofuku K; Nishimura J; Kobayashi S; Nakano H; Kanaide H
Effects of U46619 on intracellular Ca++ concentration and tension in human umbilical artery.
American journal of obstetrics and gynecology 1995;172(5):1414-21.
1995: Miyagi Y; Kobayashi S; Nishimura J; Fukui M; Kanaide H
Resting load regulates cytosolic calcium-force relationship of the contraction of bovine cerebrovascular smooth muscle.
The Journal of physiology 1995;484 ( Pt 1)():123-37.
1995: Hirakawa Y; Kuga T; Kobayashi S; Kanaide H; Takeshita A
Dual regulation of L-type Ca2+ channels by serotonin 2 receptor stimulation in vascular smooth muscle cells.
The American journal of physiology 1995;268(2 Pt 2):H544-9.
1995: Fukuizumi Y; Kobayashi S; Nishimura J; Kanaide H
Cytosolic calcium concentration-force relation during contractions in the rabbit femoral artery: time-dependency and stimulus specificity.
British journal of pharmacology 1995;114(2):329-38.
1995: Ushio-Fukai M; Nishimura J; Kobayashi S; Kanaide H
Endothelin-1 and endothelin-3 regulate differently vasoconstrictor responses of smooth muscle of the porcine coronary artery.
British journal of pharmacology 1995;114(1):171-9.
1995: Kanaide H
The effects of endothelin on vascular tonus.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1995;28(1):7-17.
1994: Ushio-Fukai M; Hirano K; Kanaide H
The effects of a novel vasodilator, LP-805, on cytosolic Ca2+ concentrations and on tension in rabbit isolated femoral arteries.
British journal of pharmacology 1994;113(4):1173-82.
1994: Kodama M; Yamamoto H; Kanaide H
Myosin phosphorylation and Ca2+ sensitization in porcine coronary arterial smooth muscle stimulated with endothelin-1.
European journal of pharmacology 1994;288(1):69-77.
1994: Higuchi Y; Nishimura J; Kanaide H
Motilin induces the endothelium-dependent relaxation of smooth muscle and the elevation of cytosolic calcium in endothelial cells in situ.
Biochemical and biophysical research communications 1994;202(1):346-53.
1994: Aoki H; Kobayashi S; Nishimura J; Kanaide H
Sensitivity of G-protein involved in endothelin-1-induced Ca2+ influx to pertussis toxin in porcine endothelial cells in situ.
British journal of pharmacology 1994;111(4):989-96.
1994: Chen X; Nishimura J; Hasna J; Kobayashi S; Shikasho T; Kanaide H
Protein kinase C and protein kinase A regulate the expression of angiotensin II receptor mRNA in smooth muscle cells.
European journal of pharmacology 1994;267(2):175-83.
1994: Kobayashi S; Nishimura J; Kanaide H
Cytosolic Ca2+ transients are not required for platelet-derived growth factor to induce cell cycle progression of vascular smooth muscle cells in primary culture. Actions of tyrosine kinase.
The Journal of biological chemistry 1994;269(12):9011-8.
1994: Hirakawa Y; Kuga T; Kanaide H; Takeshita A
Actions of a new Ca2+ channel antagonist, CD832, on two types of Ca2+ channels in smooth muscle.
European journal of pharmacology 1994;252(3):267-74.
1994: Aoki H; Nishimura J; Kobayashi S; Kanaide H
Relationship between cytosolic calcium concentration and force in the papaverine-induced relaxation of medial strips of pig coronary artery.
British journal of pharmacology 1994;111(2):489-96.
1993: Hirano K; Kanaide H
Cytosolic Ca2+ transients in endothelium-dependent relaxation of pig coronary artery, and effects of captopril.
European journal of pharmacology 1993;250(3):439-46.
1993: Kuroiwa M; Aoki H; Kobayashi S; Nishimura J; Kanaide H
Role of GTP-protein and endothelium in contraction induced by ethanol in pig coronary artery.
The Journal of physiology 1993;470():521-37.
1993: Watanabe C; Yamamoto H; Kobayashi S; Kanaide H
Extracellular Ca(2+)-dependent potentiation by cocaine of serotonin- and norepinephrine-induced contractions in rat vascular smooth muscle.
Circulation research 1993;72(6):1191-201.
1993: Kai T; Nishimura J; Kobayashi S; Takahashi S; Yoshitake J; Kanaide H
Effects of lidocaine on intracellular Ca2+ and tension in airway smooth muscle.
Anesthesiology 1993;78(5):954-65.
1993: Ushio-Fukai M; Abe S; Kobayashi S; Nishimura J; Kanaide H
Effects of isoprenaline on cytosolic calcium concentrations and on tension in the porcine coronary artery.
The Journal of physiology 1993;462():679-96.
1993: Hirano K; Hirano M; Kanaide H
Enhancement by captopril of bradykinin-induced calcium transients in cultured endothelial cells of the bovine aorta.
European journal of pharmacology 1993;244(2):133-7.
1993: Watanabe C; Hirano K; Kanaide H
Role of extracellular and intracellular sources of Ca2+ in sarafotoxin S6b-induced contraction of strips of the rat aorta.
British journal of pharmacology 1993;108(1):30-7.
1992: Nishimura J; Kobayashi S; Shikasho T; Kanaide H
Platelet derived growth factor induces c-fos and c-myc mRNA in rat aortic smooth muscle cells in primary culture without elevation of intracellular Ca2+ concentration.
Biochemical and biophysical research communications 1992;188(3):1198-204.
1992: Watanabe C; Yamamoto H; Hirano K; Kobayashi S; Kanaide H
Mechanisms of caffeine-induced contraction and relaxation of rat aortic smooth muscle.
The Journal of physiology 1992;456():193-213.
1992: Nishimura J; Chen X; Jahan H; Shikasho T; Kobayashi S; Kanaide H
cAMP induces up-regulation of ETA receptor mRNA and increases responsiveness to endothelin-1 of rat aortic smooth muscle cells in primary culture.
Biochemical and biophysical research communications 1992;188(2):719-26.
1992: Ushio-Fukai M; Nishimura J; Aoki H; Kobayashi S; Kanaide H
Endothelin-1 inhibits and enhances contraction of porcine coronary arterial strips with an intact endothelium.
Biochemical and biophysical research communications 1992;184(1):518-24.
1992: Natori Y; Moriguchi M; Fujiwara S; Takeshita I; Fukui M; Iwaki T; Kanaide H
Effects of L-NMMA and L-NNA on the selective ATP-induced enhancement of intratumoral blood flow.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(1):120-7.
1992: Nishimura J; Kobayashi S; Shikasho T; Kanaide H
Platelet-derived growth factor induces c-fos and c-myc mRNA in cultured rat aortic smooth muscle cells irrespective of intracellular Ca2+ levels.
Japanese journal of pharmacology 1992;58 Suppl 2():413P.
1992: Kobayashi S; Nishimura J; Kanaide H
Platelet-derived growth factor induces Ca2+ transients and proliferation of vascular smooth muscle cells: a role of tyrosine kinase.
Japanese journal of pharmacology 1992;58 Suppl 2():412P.
1992: Fukuizumi Y; Kobayashi S; Nishimura J; Kanaide H
Temporal changes in the Ca(2+)-force relationship during norepinephrine-, serotonin- and high K(+)-induced contractions in the rabbit femoral artery.
Japanese journal of pharmacology 1992;58 Suppl 2():277P.
1992: Hirakawa Y; Kuga T; Kanaide H; Takeshita A
Dual regulation of L-type calcium channels by S2 receptor stimulation in vascular smooth muscle cells.
Japanese journal of pharmacology 1992;58 Suppl 2():405P.
1991: Aoki H; Kobayashi S; Nishimura J; Yamamoto H; Kanaide H
Endothelin induces the Ca(2+)-transient in endothelial cells in situ.
Biochemical and biophysical research communications 1991;181(3):1352-7.
1991: Kai H; Kanaide H
[Intracellular signal transduction induced by endothelin]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(14):2372-80.
1991: Yamamoto H; Kanaide H; Nakamura M
Dextran sulfate inhibits the inositol 1,4,5-trisphosphate-induced Ca2+ release from skinned and cultured smooth muscle cells.
European journal of pharmacology 1991;206(3):175-9.
1991: Shogakiuchi Y; Kanaide H; Nakamura M
Cytosolic calcium transients differ between porcine coronary arterial and aortic smooth muscle cells in primary culture.
Circulation research 1991;68(3):818-26.
1991: Hirano K; Kanaide H; Abe S; Nakamura M
Temporal changes in the calcium-force relation during histamine-induced contractions of strips of the coronary artery of the pig.
British journal of pharmacology 1991;102(1):27-34.
1991: Yoshitake K; Hirano K; Kanaide H
Effects of glibenclamide on cytosolic calcium concentrations and on contraction of the rabbit aorta.
British journal of pharmacology 1991;102(1):113-8.
1990: Abe S; Kanaide H; Nakamura M
Front-surface fluorometry with fura-2 and effects of nitroglycerin on cytosolic calcium concentrations and on tension in the coronary artery of the pig.
British journal of pharmacology 1990;101(3):545-52.
1990: Hirano K; Kanaide H; Abe S; Nakamura M
Effects of diltiazem on calcium concentrations in the cytosol and on force of contractions in porcine coronary arterial strips.
British journal of pharmacology 1990;101(2):273-80.
1990: Kuga T; Sadoshima J; Tomoike H; Kanaide H; Akaike N; Nakamura M
Actions of Ca2+ antagonists on two types of Ca2+ channels in rat aorta smooth muscle cells in primary culture.
Circulation research 1990;67(2):469-80.
1990: Meno H; Kanaide H
[Calcium overload and myocardial injury]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(10):1845-53.
1990: Yamamoto H; Kanaide H; Nakamura M
Heparin specifically inhibits the inositol 1,4,5-trisphosphate-induced Ca2+ release from skinned rat aortic smooth muscle cells in primary culture.
Naunyn-Schmiedeberg's archives of pharmacology 1990;341(4):273-8.
1990: Matsumoto T; Kanaide H; Shogakiuchi Y; Nakamura M
Characteristics of the histamine-sensitive calcium store in vascular smooth muscle. Comparison with norepinephrine- or caffeine-sensitive stores.
The Journal of biological chemistry 1990;265(10):5610-6.
1990: Yamamoto H; Kanaide H
Release of intracellularly stored Ca2+ by inositol 1,4,5-trisphosphate--an overview.
General pharmacology 1990;21(4):387-93.
1990: Hirano K; Kanaide H; Nakamura M
Effects of okadaic acid on cytosolic calcium concentration and contraction of porcine coronary artery.
Advances in second messenger and phosphoprotein research 1990;24():461-6.
1989: Hirano K; Kanaide H; Nakamura M
Effects of okadaic acid on cytosolic calcium concentrations and on contractions of the porcine coronary artery.
British journal of pharmacology 1989;98(4):1261-6.
1989: Kai H; Kanaide H; Nakamura M
Effects of nicorandil on cytosolic calcium concentrations in quin2-loaded rat aortic vascular smooth muscle cells in primary culture.
The Journal of pharmacology and experimental therapeutics 1989;251(3):1174-80.
1989: Akaike N; Kanaide H; Kuga T; Nakamura M; Sadoshima J; Tomoike H
Low-voltage-activated calcium current in rat aorta smooth muscle cells in primary culture.
The Journal of physiology 1989;416():141-60.
1989: Matsumoto T; Kanaide H; Nishimura J; Kuga T; Kobayashi S; Nakamura M
Histamine-induced calcium transients in vascular smooth muscle cells: effects of verapamil and diltiazem.
The American journal of physiology 1989;257(2 Pt 2):H563-70.
1989: Nishimura J; Kanaide H; Miwa-Nishimura N; Nakamura M
Selective blockade of alpha 1-adrenoceptors of porcine vascular smooth muscle cells by bunazosin.
Arzneimittel-Forschung 1989;39(6):668-9.
1989: Kodama M; Kanaide H; Abe S; Hirano K; Kai H; Nakamura M
Endothelin-induced Ca-independent contraction of the porcine coronary artery.
Biochemical and biophysical research communications 1989;160(3):1302-8.
1989: Kai H; Kanaide H; Nakamura M
Endothelin-sensitive intracellular Ca2+ store overlaps with caffeine-sensitive one in rat aortic smooth muscle cells in primary cultures.
Biochemical and biophysical research communications 1989;158(1):235-43.
1989: Sadoshima J; Akaike N; Tomoike H; Kanaide H; Nakamura M
Voltage-dependent anion-selective channels in cultured smooth muscle cells of the rat aorta.
Comparative biochemistry and physiology. A, Comparative physiology 1989;92(1):61-3.
1988: Miasiro N; Yamamoto H; Kanaide H; Nakamura M
Does endothelin mobilize calcium from intracellular store sites in rat aortic vascular smooth muscle cells in primary culture?
Biochemical and biophysical research communications 1988;156(1):312-7.
1988: Sadoshima J; Akaike N; Kanaide H; Nakamura M
Cyclic AMP modulates Ca-activated K channel in cultured smooth muscle cells of rat aortas.
The American journal of physiology 1988;255(4 Pt 2):H754-9.
1988: Sadoshima J; Akaike N; Tomoike H; Kanaide H; Nakamura M
Ca-activated K channel in cultured smooth muscle cells of rat aortic media.
The American journal of physiology 1988;255(3 Pt 2):H410-8.
1988: Kanaide H; Kobayashi S; Nishimura J; Hasegawa M; Shogakiuchi Y; Matsumoto T; Nakamura M
Quin2 microfluorometry and effects of verapamil and diltiazem on calcium release from rat aorta smooth muscle cells in primary culture.
Circulation research 1988;63(1):16-26.

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