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Yuzuru Kanakura

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Takahiro Matsui; Hidekazu Tahara; Yuzuru Kanakura; Yumi Kinugasa; Nobuyuki Takakura
Possible role of mural cell-covered mature blood vessels in inducing drug resistance in cancer-initiating cells.
Yasuyoshi Morita; Jun-ichi Nishimura; Kentaro Serizawa; Takahiro Shimada; Hirokazu Tanaka; Yasuhiro Taniguchi; Mitsuhiro Tsuritani; Yuzuru Kanakura; Itaru Matsumura
Successful anticoagulant therapy for two pregnant PNH patients, and prospects for the eculizumab era.
Shinichiro Okamoto; Jonathan Smith; Steven Troy; Brihad Abhyankar; Ian Hodgson; Yoshitaka Miyakawa; Yuzuru Kanakura
Open-label, dose-titration and continuation study to assess efficacy, safety, and pharmacokinetics of anagrelide in treatment-naïve Japanese patients with essential thrombocythemia.

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2013: Takahiro Matsui; Hidekazu Tahara; Yuzuru Kanakura; Yumi Kinugasa; Nobuyuki Takakura
Possible role of mural cell-covered mature blood vessels in inducing drug resistance in cancer-initiating cells.
The American journal of pathology 2013;182(5):1790-9.
2013: Yasuyoshi Morita; Jun-ichi Nishimura; Kentaro Serizawa; Takahiro Shimada; Hirokazu Tanaka; Yasuhiro Taniguchi; Mitsuhiro Tsuritani; Yuzuru Kanakura; Itaru Matsumura
Successful anticoagulant therapy for two pregnant PNH patients, and prospects for the eculizumab era.
International journal of hematology 2013;97(4):491-7.
2013: Shinichiro Okamoto; Jonathan Smith; Steven Troy; Brihad Abhyankar; Ian Hodgson; Yoshitaka Miyakawa; Yuzuru Kanakura
Open-label, dose-titration and continuation study to assess efficacy, safety, and pharmacokinetics of anagrelide in treatment-naïve Japanese patients with essential thrombocythemia.
International journal of hematology 2013;97(3):360-8.
2013: Tsuyoshi Nakazawa; Seiji Tadokoro; Shigenori Honda; Tsuyoshi Kamae; Yuzuru Kanakura; Hirokazu Kashiwagi; Kazunobu Kiyomizu; Yoshiaki Tomiyama
Agonist stimulation, talin-1, and kindlin-3 are crucial for α(IIb)β(3) activation in a human megakaryoblastic cell line, CMK.
Experimental hematology 2013;41(1):79-90.e1.
2012: Kazunobu Kiyomizu; Tsuyoshi Nakazawa; Seiji Tadokoro; Shigenori Honda; Yuzuru Kanakura; Hirokazu Kashiwagi; Yoshiaki Tomiyama
Recognition of highly restricted regions in the β-propeller domain of αIIb by platelet-associated anti-αIIbβ3 autoantibodies in primary immune thrombocytopenia.
Blood 2012;120(7):1499-509.
2012: Jun-Ichi Nishimura; Yuzuru Kanakura
[Bone marrow failure syndrome (idiopathic hematopoietic disorders): progress in diagnosis and treatment. Topics: III. Diagnosis and treatments; 4. Paroxysmal nocturnal hemoglobinuria].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2012;101(7):1953-9.
2012: Takao Sudo; Tatsuki Sugiyama; Hirokazu Tanaka; Takafumi Yokota; Sachiko Ezoe; Natsuko Fujita; Tatsuro Ishida; Tetsuo Maeda; Takashi Nagasawa; Kenji Oritani; Yusuke Satoh; Hirohiko Shibayama; Yuzuru Kanakura
The endothelial antigen ESAM monitors hematopoietic stem cell status between quiescence and self-renewal.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(1):200-10.
2012: Yoshiaki Tomiyama; T Hattori; Y Ikeda; K Katsura; S Katsutani; A Kimura; H Kosugi; Y Miyakawa; H Ninomiya; S Nomura; S Okamoto; Y Okoshi; K Ozaki; Yuzuru Kanakura
A lower starting dose of eltrombopag is efficacious in Japanese patients with previously treated chronic immune thrombocytopenia.
Journal of thrombosis and haemostasis : JTH 2012;10(5):799-806.
2012: Naoki Wada; Mona A A Zaki; Masayuki Hino; Hiroshi Inagaki; Yuzuru Kanakura; Masaharu Kohara; Itaru Matsumura; Eiichi Morii; Shosaku Nomura; Hiroyasu Ogawa; Haruo Sugiyama; Katsuyuki Aozasa
Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka Lymphoma Study Group.
Histopathology 2012;60(6):924-32.
2012: Masao Mizuki; Yuzuru Kanakura
[Pathogenesis, diagnosis and treatment of mastocytosis].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 2():337-41.
2012: Keiko Matsui; Itaru Matsumura; Michael W McBurney; Kenji Oritani; Masaru Shibata; Takao Sudo; Hirokazu Tanaka; Akira Tanimura; Masahiro Tokunaga; Sachiko Ezoe; Natsuko Fujita; Yuzuru Kanakura
NAD-dependent histone deacetylase, SIRT1, plays essential roles in the maintenance of hematopoietic stem cells.
Biochemical and biophysical research communications 2012;418(4):811-7.
2012: Mai Suzuki; Kohji Takei; Kenji Tanabe; Hirokazu Tanaka; Akira Tanimura; Takaya Abe; Manabu Fukumoto; Yuzuru Kanakura; Syunsuke Kon; Itaru Matsumura; Natsuko Oe; Shinya Rai; Toshio Watanabe
The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.
PloS one 2012;7(2):e31854.
2011: Masaru Shibata; Takayuki Takahashi; Masahiro Tokunaga; Sachiko Ezoe; Natsuko Fujita; Masayuki Hino; Keiko Matsui; Itaru Matsumura; Kenji Oritani; Yuri Saito; Yuzuru Kanakura
Predictability of the response to tyrosine kinase inhibitors via in vitro analysis of Bcr-Abl phosphorylation.
Leukemia research 2011;35(9):1205-11.
2011: Jun-Ichi Nishimura; Yuzuru Kanakura
[The cutting-edge of medicine: etiology, pathogenesis and treatment in PNH].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(7):1994-9.
2011: Yuri Saito; Hirohiko Shibayama; Hirokazu Tanaka; Akira Tanimura; Itaru Matsumura; Yuzuru Kanakura
PICOT is a molecule which binds to anamorsin.
Biochemical and biophysical research communications 2011;408(2):329-33.
2011: Mona A A Zaki; Naoki Wada; Masaharu Kohara; Junichiro Ikeda; Yumiko Hori; Shigeki Fujita; Hiroyasu Ogawa; Haruo Sugiyama; Masayuki Hino; Yuzuru Kanakura; Eiichi Morii; Katsuyuki Aozasa
Presence of B-cell clones in T-cell lymphoma.
European journal of haematology 2011;86(5):412-9.
2011: Tsuyoshi Kamae; K Kiyomizu; T Nakazawa; Seiji Tadokoro; Hirokazu Kashiwagi; Shigenori Honda; Yuzuru Kanakura; Yoshiaki Tomiyama
Bleeding tendency and impaired platelet function in a patient carrying a heterozygous mutation in the thromboxane A2 receptor.
Journal of thrombosis and haemostasis : JTH 2011;9(5):1040-8.
2011: Jiro Fujita; Masao Mizuki; Masayasu Otsuka; Sachiko Ezoe; Hirokazu Tanaka; Yusuke Satoh; Kentaro Fukushima; Masahiro Tokunaga; Itaru Matsumura; Yuzuru Kanakura
Myeloid neoplasm-related gene abnormalities differentially affect dendritic cell differentiation from murine hematopoietic stem/progenitor cells.
Immunology letters 2011;136(1):61-73.
2011: Kyung-Ah Park; Nuri Yun; Dong-Ik Shin; So Yoen Choi; Hyun Kim; Won-Ki Kim; Yuzuru Kanakura; Hirohiko Shibayama; Young J Oh
Nuclear translocation of anamorsin during drug-induced dopaminergic neurodegeneration in culture and in rat brain.
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(3):433-44.
2011: Yuri Saito; Hirohiko Shibayama; Hirokazu Tanaka; Akira Tanimura; Yuzuru Kanakura
A cell-death-defying factor, anamorsin mediates cell growth through inactivation of PKC and p38MAPK.
Biochemical and biophysical research communications 2011;405(2):303-7.
2011: Naoki Wada; Junichiro Ikeda; Yumiko Hori; Shigeki Fujita; Hiroyasu Ogawa; Toshihiro Soma; Haruo Sugiyama; Shirou Fukuhara; Akihisa Kanamaru; Masayuki Hino; Yuzuru Kanakura; Eiichi Morii; Katsuyuki Aozasa
Epstein-barr virus in diffuse large B-Cell lymphoma in immunocompetent patients in Japan is as low as in Western Countries.
Journal of medical virology 2011;83(2):317-21.
2011: Seiji Tadokoro; Tsuyoshi Nakazawa; Tsuyoshi Kamae; Kazunobu Kiyomizu; Hirokazu Kashiwagi; Shigenori Honda; Yuzuru Kanakura; Yoshiaki Tomiyama
A potential role for α-actinin in inside-out αIIbβ3 signaling.
Blood 2011;117(1):250-8.
2011: Shugo Sasaki; Masataka Hasegawa; Koji Hashimoto; Yuzuru Kanakura; Seiki Nagata; Tomoaki Nakano; Shin-ichi Nakatsuka; Norio Hayashi
Plasmablastic extramedullary plasmacytoma associated with Epstein-Barr virus arising in an immunocompetent patient with multiple myeloma.
Internal medicine (Tokyo, Japan) 2011;50(21):2615-20.
2011: Takeshi Chihara; Naoki Wada; Junichiro Ikeda; Shigeki Fujita; Yumiko Hori; Hiroyasu Ogawa; Haruo Sugiyama; Shosaku Nomura; Itaru Matsumura; Masayuki Hino; Yuzuru Kanakura; Eiichi Morii; Katsuyuki Aozasa
Frequency of intravascular large B-cell lymphoma in Japan: study of the Osaka Lymphoma Study Group.
Journal of hematology & oncology 2011;4():14.
2011: Masayasu Otsuka; Masao Mizuki; Jiro Fujita; Sumin Kang; Yuzuru Kanakura
Constitutively active FGFR3 with Lys650Glu mutation enhances bortezomib sensitivity in plasma cell malignancy.
Anticancer research 2011;31(1):113-22.
2011: Takahiro Hashimoto; Yasushi Sakata; Kentaro Fukushima; Tetsuo Maeda; Yukio Arita; Wataru Shioyama; Yoshikazu Nakaoka; Yumiko Hori; Eiichi Morii; Katsuyuki Aozasa; Yuzuru Kanakura; Keiko Yamauchi-Takihara; Issei Komuro
Pulmonary arterial hypertension associated with chronic active Epstein-Barr virus infection.
Internal medicine (Tokyo, Japan) 2011;50(2):119-24.
2011: Yuzuru Kanakura; Kazuma Ohyashiki; Tsutomu Shichishima; Shinichiro Okamoto; Kiyoshi Ando; Haruhiko Ninomiya; Tatsuya Kawaguchi; Shinji Nakao; Hideki Nakakuma; Jun-ichi Nishimura; Taroh Kinoshita; Camille L Bedrosian; Marye Ellen Valentine; Gus Khursigara; Keiya Ozawa; Mitsuhiro Omine
Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria: the AEGIS clinical trial.
International journal of hematology 2011;93(1):36-46.
2011: Hirokazu Kashiwagi; Kazunobu Kiyomizu; Tsuyoshi Kamae; Tsuyoshi Nakazawa; Seiji Tadokoro; Shuji Takiguchi; Yuichiro Doki; Yuzuru Kanakura; Yoshiaki Tomiyama
Molecular analysis of a patient with type I Glanzmann thrombasthenia and clinical impact of the presence of anti-αIIbβ3 alloantibodies.
International journal of hematology 2011;93(1):106-11.
2011: Norimitsu Saitoh; Kenji Oritani; Kazunobu Saito; Takafumi Yokota; Michiko Ichii; Takao Sudo; Natsuko Fujita; Koichi Nakajima; Masato Okada; Yuzuru Kanakura
Identification of functional domains and novel binding partners of STIM proteins.
Journal of cellular biochemistry 2011;112(1):147-56.
2010: Masahiro Tokunaga; Sachiko Ezoe; Hirokazu Tanaka; Yusuke Satoh; Kentaro Fukushima; Keiko Matsui; Masaru Shibata; Akira Tanimura; Kenji Oritani; Itaru Matsumura; Yuzuru Kanakura
BCR-ABL but not JAK2 V617F inhibits erythropoiesis through the Ras signal by inducing p21CIP1/WAF1.
The Journal of biological chemistry 2010;285(41):31774-82.
2010: Yoh Arita; Yasushi Sakata; Takao Sudo; Tetsuo Maeda; Ken Matsuoka; Keito Tamai; Kaori Higuchi; Wataru Shioyama; Yoshikazu Nakaoka; Yuzuru Kanakura; Keiko Yamauchi-Takihara
The efficacy of tocilizumab in a patient with pulmonary arterial hypertension associated with Castleman's disease.
Heart and vessels 2010;25(5):444-7.
2010: Michiko Ichii; Kenji Oritani; Takafumi Yokota; Daniel C Schultz; Jennifer L Holter; Yuzuru Kanakura; Paul W Kincade
Stromal cell-free conditions favorable for human B lymphopoiesis in culture.
Journal of immunological methods 2010;359(1-2):47-55.
2010: Naoki Wada; Masaharu Kohara; Junichiro Ikeda; Yumiko Hori; Shigeki Fujita; Masaya Okada; Hiroyasu Ogawa; Haruo Sugiyama; Shirou Fukuhara; Akihisa Kanamaru; Masayuki Hino; Yuzuru Kanakura; Eiichi Morii; Katsuyuki Aozasa
Diffuse large B-cell lymphoma in the spinal epidural space: A study of the Osaka Lymphoma Study Group.
Pathology, research and practice 2010;206(7):439-44.
2010: Tadashi Nagai; Jin Takeuchi; Nobuaki Dobashi; Yuzuru Kanakura; Shuichi Taniguchi; Koji Ezaki; Chiaki Nakaseko; Akira Hiraoka; Masaya Okada; Yasushi Miyazaki; Toshiko Motoji; Masaaki Higashihara; Norifumi Tsukamoto; Hitoshi Kiyoi; Shinji Nakao; Katsuji Shinagawa; Ryuzo Ohno; Tomoki Naoe; Kazunori Ohnishi; Noriko Usui
Imatinib for newly diagnosed chronic-phase chronic myeloid leukemia: results of a prospective study in Japan.
International journal of hematology 2010;92(1):111-7.
2010: Takeshi Chihara; Naoki Wada; Masaharu Kohara; Takako Matsui; Hiroaki Masaya; Tetsuo Maeda; Hirohiko Shibayama; Yuzuru Kanakura; Mamori Tani; Eiichi Morii; Katsuyuki Aozasa
Peripheral T-cell lymphoma of Lennert type complicated by monoclonal proliferation of large B-cells.
Pathology, research and practice 2010;206(3):185-90.
2010: Naoto Nakamichi; Naoki Wada; Masaharu Kohara; Shirou Fukuhara; Haruo Sugiyama; Hiroyasu Ogawa; Masayuki Hino; Akihisa Kanamaru; Yuzuru Kanakura; Eiichi Morii; Katsuyuki Aozasa
Polymorphous lymphoproliferative disorder: a clinicopathological analysis.
Virchows Archiv : an international journal of pathology 2010;456(3):269-76.
2010: Michiko Ichii; Kenji Oritani; Takafumi Yokota; Qingzhao Zhang; Karla P Garrett; Yuzuru Kanakura; Paul W Kincade
The density of CD10 corresponds to commitment and progression in the human B lymphoid lineage.
PloS one 2010;5(9):e12954.
2009: Yuzuru Kanakura
[Diagnosis and treatment of paroxysmal nocturnal hemoglobinuria].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2009;50(10):1469-76.
2009: Jun Ishikawa; Tetsuo Maeda; Itaru Matsumura; Masato Yasumi; Hidetoshi Ujiie; Hiroaki Masaie; Tsuyoshi Nakazawa; Nobuo Mochizuki; Satoshi Kishino; Yuzuru Kanakura
Antifungal activity of micafungin in serum.
Antimicrobial agents and chemotherapy 2009;53(10):4559-62.
2009: Naoki Wada; Junichiro Ikeda; Masaharu Kohara; Hiroyasu Ogawa; Masayuki Hino; Shirou Fukuhara; Akihisa Kanamaru; Haruo Sugiyama; Yuzuru Kanakura; Eiichi Morii; Katsuyuki Aozasa
Diffuse large B-cell lymphoma with a high number of epithelioid histiocytes (lymphoepithelioid B-cell lymphoma): a study of Osaka Lymphoma Study Group.
Virchows Archiv : an international journal of pathology 2009;455(3):285-93.
2009: M Akiyama; Hirokazu Kashiwagi; K Todo; M Moroi; M C Berndt; H Kojima; Yuzuru Kanakura; Yoshiaki Tomiyama
Presence of platelet-associated anti-glycoprotein (GP)VI autoantibodies and restoration of GPVI expression in patients with GPVI deficiency.
Journal of thrombosis and haemostasis : JTH 2009;7(8):1373-83.
2009: Mitsuaki Tatsumi; Hiroyuki Sugahara; Ichiro Higuchi; Hiroki Fukunaga; Hironobu Nakamura; Yuzuru Kanakura; Jun Hatazawa
Standardized uptake value on FDG-PET as a marker for disease activity in patients with non-Hodgkin's lymphoma: comparison with serum soluble interleukin-2 receptor values.
International journal of clinical oncology 2009;14(2):150-8.
2009: Takafumi Yokota; Kenji Oritani; Stefan Butz; Koichi Kokame; Paul W Kincade; Toshiyuki Miyata; Dietmar Vestweber; Yuzuru Kanakura
The endothelial antigen ESAM marks primitive hematopoietic progenitors throughout life in mice.
Blood 2009;113(13):2914-23.
2009: Kentaro Fukushima; Itaru Matsumura; Sachiko Ezoe; Masahiro Tokunaga; Masato Yasumi; Yusuke Satoh; Hirohiko Shibayama; Hirokazu Tanaka; Atsushi Iwama; Yuzuru Kanakura
FIP1L1-PDGFRalpha imposes eosinophil lineage commitment on hematopoietic stem/progenitor cells.
The Journal of biological chemistry 2009;284(12):7719-32.
2009: Itsuko Nakamichi; Kouki Shimazu; Jun-ichiro Ikeda; Amane Yamauchi; Jun Ishiko; Masao Mizuki; Yuzuru Kanakura; Katsuyuki Aozasa
Intravascular lymphomatosis initially suspected from uterine cytology: a case report.
Acta cytologica 2009;53(2):198-200.
2009: Shigeru Miyagawa; Goro Matsumiya; Toshihiro Funatsu; Masao Yoshitatsu; Naozumi Sekiya; Shinya Fukui; Takaya Hoashi; Masatsugu Hori; Hideki Yoshikawa; Yuzuru Kanakura; Jun Ishikawa; Katsuyuki Aozasa; Naomasa Kawaguchi; Nariaki Matsuura; Akira Myoui; Akifumi Matsuyama; Sachiko Ezoe; Hidehiro Iida; Hikaru Matsuda; Yoshiki Sawa
Combined autologous cellular cardiomyoplasty using skeletal myoblasts and bone marrow cells for human ischemic cardiomyopathy with left ventricular assist system implantation: report of a case.
Surgery today 2009;39(2):133-6.
2008: Kayako Isohashi; Mitsuaki Tatsumi; Ichiro Higuchi; Atsuo Inoue; Kazuya Nakajo; Jun Ishikawa; Eku Shimosegawa; Yuzuru Kanakura; Hironobu Nakamura; Jun Hatazawa
18F-FDG-PET in patients with malignant lymphoma having long-term follow-up: staging and restaging, and evaluation of treatment response and recurrence.
Annals of nuclear medicine 2008;22(9):795-802.
2008: Takafumi Yokota; Kenji Oritani; Karla P Garrett; Taku Kouro; Makoto Nishida; Isao Takahashi; Michiko Ichii; Yusuke Satoh; Paul W Kincade; Yuzuru Kanakura
Soluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(9):6061-72.
2008: Yusuke Satoh; Itaru Matsumura; Hirokazu Tanaka; Sachiko Ezoe; Kentaro Fukushima; Masahiro Tokunaga; Masato Yasumi; Hirohiko Shibayama; Masao Mizuki; Takumi Era; Tsukasa Okuda; Yuzuru Kanakura
AML1/RUNX1 works as a negative regulator of c-Mpl in hematopoietic stem cells.
The Journal of biological chemistry 2008;283(44):30045-56.
2008: Amane Yamauchi; Jun-Ichiro Ikeda; Itsuko Nakamichi; M Kohara; S Fukuhara; Masayuki Hino; Yuzuru Kanakura; Hiroyasu Ogawa; Haruo Sugiyama; Akihisa Kanamaru; Katsuyuki Aozasa
Diffuse large B-cell lymphoma showing an interfollicular pattern of proliferation: a study of the Osaka Lymphoma Study Group.
Histopathology 2008;52(6):731-7.
2008: Junzo Nojima; Y Masuda; Yoshinori Iwatani; Hirohiko Kuratsune; Y Watanabe; Etsuji Suehisa; T Takano; Y Hidaka; Yuzuru Kanakura
Arteriosclerosis obliterans associated with anti-cardiolipin antibody/beta2-glycoprotein I antibodies as a strong risk factor for ischaemic heart disease in patients with systemic lupus erythematosus.
Rheumatology (Oxford, England) 2008;47(5):684-9.
2008: Michiko Ichii; Kenji Oritani; Takafumi Yokota; Makoto Nishida; Isao Takahashi; Takahiro Shirogane; Sachiko Ezoe; Norimitsu Saitoh; Rie Tanigawa; Paul W Kincade; Yuzuru Kanakura
Regulation of human B lymphopoiesis by the transforming growth factor-beta superfamily in a newly established coculture system using human mesenchymal stem cells as a supportive microenvironment.
Experimental hematology 2008;36(5):587-97.
2008: Hiroshi Sasaki; Jun Hayakawa; Y Terai; Masanori Kanemura; A Tanabe-Kimura; H Kamegai; H Seino-Noda; Sachiko Ezoe; Itaru Matsumura; Yuzuru Kanakura; Masahiro Sakata; Keiichi Tasaka; Masahide Ohmichi
Difference between genomic actions of estrogen versus raloxifene in human ovarian cancer cell lines.
Oncogene 2008;27(19):2737-45.
2008: Jun-ichi Nishimura; Yuzuru Kanakura
[Paroxysmal nocturnal hemoglobinuria (PNH)].
Nihon rinsho. Japanese journal of clinical medicine 2008;66(3):490-6.
2008: Itaru Matsumura; Yuzuru Kanakura
[Pathogenesis of anemia of chronic disease].
Nihon rinsho. Japanese journal of clinical medicine 2008;66(3):535-9.
2008: Itaru Matsumura; Masao Mizuki; Yuzuru Kanakura
Roles for deregulated receptor tyrosine kinases and their downstream signaling molecules in hematologic malignancies.
Cancer science 2008;99(3):479-85.
2008: Junzo Nojima; Yumiko Masuda; Yoshinori Iwatani; Etsuji Suehisa; Yoshiaki Futsukaichi; Hirohiko Kuratsune; Yasuyoshi Watanabe; Toru Takano; Yoh Hidaka; Yuzuru Kanakura
Tissue factor expression on monocytes induced by anti-phospholipid antibodies as a strong risk factor for thromboembolic complications in SLE patients.
Biochemical and biophysical research communications 2008;365(1):195-200.
2008: Takae Shizusawa; Hirohiko Shibayama; Shinsuke Murata; Yuri Saitoh; Yuna Sugimoto; Itaru Matsumura; Hiroyasu Ogawa; Haruo Sugiyama; Shirou Fukuhara; Masayuki Hino; Akihisa Kanamaru; Amane Yamauchi; Katsuyuki Aozasa; Yuzuru Kanakura
The expression of anamorsin in diffuse large B cell lymphoma: possible prognostic biomarker for low IPI patients.
Leukemia & lymphoma 2008;49(1):113-21.
2007: Junzo Nojima; Akikazu Sakudo; Yukiko Hakariya; Hirohiko Kuratsune; Yasuyoshi Watanabe; Yuzuru Kanakura; Kazuyoshi Ikuta
Spectroscopic diagnosis of anti-phospholipid antibodies by visible and near-infrared spectroscopy in SLE patients' plasma samples.
Biochemical and biophysical research communications 2007;362(2):522-4.
2007: Amane Yamauchi; Shigeki Fujita; Jun-Ichiro Ikeda; Itsuko Nakamichi; Shiro Fukuhara; Masayuki Hino; Yuzuru Kanakura; Hiroyasu Ogawa; Haruo Sugiyama; Akihisa Kanamaru; Katsuyuki Aozasa
Diffuse large B-cell lymphoma in the young in Japan: a study by the Osaka Lymphoma Study Group.
American journal of hematology 2007;82(10):893-7.
2007: Jun Ishiko; Masao Mizuki; Masato Yasumi; Hidetoshi Ujiie; Itsuko Nakamichi; Katsuyuki Aozasa; Yuzuru Kanakura
An indolent subtype of "intravascular lymphoma": A case with a 3-year history of LDH elevation.
Leukemia & lymphoma 2007;48(9):1872-4.
2007: Motoi Kondo; Keiko Tazumi; Keiko Kouji; Natsuko Matsumura; Manabu Takegami; Nobuo Kurokawa; Yuzuru Kanakura; Shinzaburo Noguchi; Masao Mizuki
[Present situation and problems of the ordering system type infusion center].
Gan to kagaku ryoho. Cancer & chemotherapy 2007;34(8):1264-6.
2007: Itsuko Nakamichi; Yasuhiko Tomita; Binglin Zhang; Haruo Sugiyama; Yuzuru Kanakura; Shirou Fukuhara; Masayuki Hino; Akihisa Kanamaru; Hiroyasu Ogawa; Katsuyuki Aozasa
Correlation between promoter hypermethylation of GSTP1 and response to chemotherapy in diffuse large B cell lymphoma.
Annals of hematology 2007;86(8):557-64.
2007: Hiroaki Masaie; Kenji Oritani; Takafumi Yokota; Ichiro Takahashi; Takahiro Shirogane; Hidetoshi Ujiie; Michiko Ichii; Norimitsu Saitoh; Tetsuo Maeda; Rie Tanigawa; Kazumasa Oka; Yoshihiko Hoshida; Yoshiaki Tomiyama; Yuzuru Kanakura
Adiponectin binds to chemokines via the globular head and modulates interactions between chemokines and heparan sulfates.
Experimental hematology 2007;35(6):947-56.
2007: Masaaki Takatoku; Takashi Uchiyama; Shinichiro Okamoto; Yuzuru Kanakura; Kenichi Sawada; Masao Tomonaga; Shinji Nakao; Tatsutoshi Nakahata; Mine Harada; Takashi Murate; Keiya Ozawa
Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality.
European journal of haematology 2007;78(6):487-94.
2007: Hachiro Yamanishi; Shigeki Kimura; Nobuaki Hata; Shigeru Iyama; Yuzuru Kanakura; Yoshinori Iwatani
Evaluation of a model of latent pathologic factors in relation to serum ferritin elevation.
Clinical biochemistry 2007;40(5-6):359-64.
2007: Itaru Matsumura; Yuzuru Kanakura
[Molecular abnormalities involved in leukemogenesis].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 1():100-4.
2007: Hachiro Yamanishi; Nobuko Imai; Etsuji Suehisa; Yuzuru Kanakura; Yoshinori Iwatani
Determination of leukocyte counts in cerebrospinal fluid with a disposable plastic hemocytometer.
Journal of clinical laboratory analysis 2007;21(5):282-5.
2007: Osamu Kabutomori; Yuzuru Kanakura; Yoshinori Iwatani
Characteristic changes in platelet-large cell ratio, lactate dehydrogenase and C-reactive protein in thrombocytosis-related diseases.
Acta haematologica 2007;118(2):84-7.
2006: Norimitsu Inoue; Tomohisa Izui-Sarumaru; Yoshiko Murakami; Yuichi Endo; Jun-Ichi Nishimura; Ken Kurokawa; Maki Kuwayama; Hiroaki Shime; Takashi Machii; Yuzuru Kanakura; Gabrielle Meyers; Carl Wittwer; Zhong Chen; William Babcock; Debra Frei-Lahr; Charles J Parker; Taroh Kinoshita
Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH).
Blood 2006;108(13):4232-6.
2006: Hitoshi Yoshida; Tetsuo Maeda; Jun Ishikawa; Shinya Inoue; Hitomi Matsunaga; Satoru Kosugi; Masamichi Shiraga; Kenji Oritani; Yuzuru Kanakura; Yoshiaki Tomiyama
Expression of CD27 on peripheral CD4+ T-lymphocytes correlates with the development of severe acute graft-versus-host disease after allogeneic bone marrow transplantation.
International journal of hematology 2006;84(4):367-76.
2006: Hirokazu Tanaka; Itaru Matsumura; Kiminari Itoh; Asako Hatsuyama; Masayuki Shikamura; Yusuke Satoh; Toshio Heike; Tatsutoshi Nakahata; Yuzuru Kanakura
HOX decoy peptide enhances the ex vivo expansion of human umbilical cord blood CD34+ hematopoietic stem cells/hematopoietic progenitor cells.
Stem cells (Dayton, Ohio) 2006;24(11):2592-602.
2006: Min Yu; Jincai Luo; Wentian Yang; Yongping Wang; Masao Mizuki; Yuzuru Kanakura; Peter Besmer; Benjamin G Neel; Haihua Gu
The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway.
The Journal of biological chemistry 2006;281(39):28615-26.
2006: H Kimura; Eiichi Morii; JI Ikeda; Sachiko Ezoe; Jing-Xian Xu; N Nakamichi; Yasuhiko Tomita; Hirohiko Shibayama; Yuzuru Kanakura; Katsuyuki Aozasa
Role of DNA methylation for expression of novel stem cell marker CDCP1 in hematopoietic cells.
Leukemia 2006;20(9):1551-6.
2006: Hachiro Yamanishi; Nobuko Imai; Toshinari Ohmine; Miho Nishiyama; Etsuji Suehisa; Yuzuru Kanakura; Yoshinori Iwatani
Urine flow cytometer quantification of leukocytes in samples containing a large proportion of lymphocytes.
Clinical biochemistry 2006;39(8):857-9.
2006: Itaru Matsumura; Yuzuru Kanakura
[Molecular targeting therapy of hematopoietic tumors].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2006;95(7):1375-81.
2006: Tsuyoshi Kamae; Masamichi Shiraga; Hirokazu Kashiwagi; Hisashi Kato; Seiji Tadokoro; Yoshiyuki Kurata; Yoshiaki Tomiyama; Yuzuru Kanakura
Critical role of ADP interaction with P2Y12 receptor in the maintenance of alpha(IIb)beta3 activation: association with Rap1B activation.
Journal of thrombosis and haemostasis : JTH 2006;4(6):1379-87.
2006: Junzo Nojima; Yoshinori Iwatani; Etsuji Suehisa; Hirohiko Kuratsune; Yuzuru Kanakura
The presence of anti-phosphatidylserine/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematosus.
Haematologica 2006;91(5):699-702.
2006: Hidetoshi Ujiie; Kenji Oritani; Hisashi Kato; Takafumi Yokota; Ichiro Takahashi; Tetsuo Maeda; Hiroaki Masaie; Michiko Ichii; Yoshihiro Kamada; Shinji Tamura; Shinji Kihara; Tohru Funahashi; Yoshiaki Tomiyama; Yuzuru Kanakura
Identification of amino-terminal region of adiponectin as a physiologically functional domain.
Journal of cellular biochemistry 2006;98(1):194-207.
2006: Hisashi Kato; Hirokazu Kashiwagi; Masamichi Shiraga; Seiji Tadokoro; Tsuyoshi Kamae; Hidetoshi Ujiie; Shigenori Honda; Shigeki Miyata; Yoshinobu Ijiri; Junichiro Yamamoto; Norikazu Maeda; Tohru Funahashi; Yoshiyuki Kurata; Iichiro Shimomura; Yoshiaki Tomiyama; Yuzuru Kanakura
Adiponectin acts as an endogenous antithrombotic factor.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):224-30.
2005: Jun Ishiko; Masao Mizuki; Itaru Matsumura; Hirohiko Shibayama; Hiroyuki Sugahara; Glen Scholz; Hubert Serve; Yuzuru Kanakura
Roles of tyrosine residues 845, 892 and 922 in constitutive activation of murine FLT3 kinase domain mutant.
Oncogene 2005;24(55):8144-53.
2005: Emiko Sakane-Ishikawa; Shin-ichi Nakatsuka; Yasuhiko Tomita; Shigeki Fujita; Itsuko Nakamichi; Tetsuya Takakuwa; Haruo Sugiyama; Shirou Fukuhara; Masayuki Hino; Akihisa Kanamaru; Toshihiro Soma; Machiko Tsukaguchi; Kazuhiko Igarashi; Yuzuru Kanakura; Katsuyuki Aozasa
Prognostic significance of BACH2 expression in diffuse large B-cell lymphoma: a study of the Osaka Lymphoma Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(31):8012-7.
2005: Norihiro Nishimoto; Yuzuru Kanakura; Katsuyuki Aozasa; Takeshi Johkoh; Minoru Nakamura; Shuji Nakano; Nobuaki Nakano; Yasuo Ikeda; Takeshi Sasaki; Kiyoshi Nishioka; Masamichi Hara; Hirokuni Taguchi; Yukihiko Kimura; Yoshiro Kato; Hideki Asaoku; Shunichi Kumagai; Fumio Kodama; Hideko Nakahara; Keisuke Hagihara; Kazuyuki Yoshizaki; Tadamitsu Kishimoto
Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease.
Blood 2005;106(8):2627-32.
2005: Masamichi Shiraga; S Miyata; Hisashi Kato; Hirokazu Kashiwagi; Shigenori Honda; Yoshiyuki Kurata; Yoshiaki Tomiyama; Yuzuru Kanakura
Impaired platelet function in a patient with P2Y12 deficiency caused by a mutation in the translation initiation codon.
Journal of thrombosis and haemostasis : JTH 2005;3(10):2315-23.
2005: Hirokazu Kashiwagi; Masamichi Shiraga; Hisashi Kato; Tsuyoshi Kamae; Naoko Yamamoto; Seiji Tadokoro; Yoshiyuki Kurata; Yoshiaki Tomiyama; Yuzuru Kanakura
Negative regulation of platelet function by a secreted cell repulsive protein, semaphorin 3A.
Blood 2005;106(3):913-21.
2005: Kenji Oritani; Yuzuru Kanakura
IFN-zeta/ limitin: a member of type I IFN with mild lympho-myelosuppression.
Journal of cellular and molecular medicine 2005;9(2):244-54.
2005: Hiroyuki Hanada; Keiko Takeoka; Tomoko Nomura; Takanori Moriyama; Yuzuru Kanakura
[Analysis of the dilution deviation in CA19-9 measurement].
Rinsho byori. The Japanese journal of clinical pathology 2005;53(4):297-302.
2005: Naoko Ishida; Kenji Oritani; Masamichi Shiraga; Hitoshi Yoshida; Sin-Ichiro Kawamoto; Hidetoshi Ujiie; Hiroaki Masaie; Michiko Ichii; Yoshiaki Tomiyama; Yuzuru Kanakura
Differential effects of a novel IFN-zeta/limitin and IFN-alpha on signals for Daxx induction and Crk phosphorylation that couple with growth control of megakaryocytes.
Experimental hematology 2005;33(4):495-503.
2005: Sachiko Ezoe; Itaru Matsumura; Karin Gale; Yusuke Satoh; Jun Ishikawa; Masao Mizuki; Satoru Takahashi; Naoko Minegishi; Koichi Nakajima; Masayuki Yamamoto; Tariq Enver; Yuzuru Kanakura
GATA transcription factors inhibit cytokine-dependent growth and survival of a hematopoietic cell line through the inhibition of STAT3 activity.
The Journal of biological chemistry 2005;280(13):13163-70.
2005: Yu-ichiro Koma; Akihiko Ito; Kenji Watabe; Tatsumi Hirata; Masao Mizuki; Hiroshi Yokozaki; Toshio Kitamura; Yuzuru Kanakura; Yukihiko Kitamura
Distinct role for c-kit receptor tyrosine kinase and SgIGSF adhesion molecule in attachment of mast cells to fibroblasts.
Laboratory investigation; a journal of technical methods and pathology 2005;85(3):426-35.
2005: Junzo Nojima; Hirohiko Kuratsune; Etsuji Suehisa; Yoshinori Iwatani; Yuzuru Kanakura
Acquired activated protein C resistance associated with IgG antibodies against beta2-glycoprotein I and prothrombin as a strong risk factor for venous thromboembolism.
Clinical chemistry 2005;51(3):545-52.
2005: Eri Ishiko; Itaru Matsumura; Sachiko Ezoe; Karin Gale; Jun Ishiko; Yusuke Satoh; Hirokazu Tanaka; Hirohiko Shibayama; Masao Mizuki; Takumi Era; Tariq Enver; Yuzuru Kanakura
Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1.
The Journal of biological chemistry 2005;280(6):4929-39.
2005: Hirokazu Kashiwagi; Masamichi Shiraga; Hisashi Kato; Shigenori Honda; Masahiro Sako; Yoshiyuki Kurata; Yuzuru Kanakura; Yoshiaki Tomiyama
Expression and subcellular localization of WAVE isoforms in the megakaryocyte/platelet lineage.
Journal of thrombosis and haemostasis : JTH 2005;3(2):361-8.
2005: Osamu Kabutomori; Yuzuru Kanakura; Yoshinori Iwatani
Inflammation markers and liver dysfunction.
Annals of hematology 2005;84(2):136.
2005: Yuzuru Kanakura
Regulation and dysregulation of hematopoiesis by a cytokine-induced antiapoptotic molecule anamorsin.
Hematology (Amsterdam, Netherlands) 2005;10 Suppl 1():73-5.
2004: Soichi Nakata; Itaru Matsumura; Hirokazu Tanaka; Sachiko Ezoe; Yusuke Satoh; Jun Ishikawa; Takumi Era; Yuzuru Kanakura
NF-kappaB family proteins participate in multiple steps of hematopoiesis through elimination of reactive oxygen species.
The Journal of biological chemistry 2004;279(53):55578-86.
2004: Dai Watanabe; Sachiko Ezoe; Minoru Fujimoto; Akihiro Kimura; Yoshiyuki Saito; Hisaki Nagai; Isao Tachibana; Itaru Matsumura; Toshio Tanaka; Hirokazu Kanegane; Toshio Miyawaki; Mitsuru Emi; Yuzuru Kanakura; Ichiro Kawase; Tetsuji Naka; Tadamitsu Kishimoto
Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines.
British journal of haematology 2004;126(5):726-35.
2004: Yuzuru Kanakura; Drew J Winston
[Antifungal prophylaxis in allogenic hematopoietic stem-cell transplant recipients].
The Japanese journal of antibiotics 2004;57(4):421-4.
2004: Yusuke Satoh; Itaru Matsumura; Hirokazu Tanaka; Sachiko Ezoe; Hiroyuki Sugahara; Masao Mizuki; Hirohiko Shibayama; Eri Ishiko; Jun Ishiko; Koichi Nakajima; Yuzuru Kanakura
Roles for c-Myc in self-renewal of hematopoietic stem cells.
The Journal of biological chemistry 2004;279(24):24986-93.
2004: Hirokazu Murakami; Hiroshi Handa; Kohzoh Imai; Yuzuru Kanakura; Masaaki Kosaka; Morio Sawamura; Chihiro Shimazaki; Kenshi Suzuki; Akihiro Ishii; Toshiyuki Takagi; Masashi Taniwaki; Atsushi Togawa; Hiroyuki Hata; Toshio Wakayama; Kiyoshi Takatsuki
[Thalidomide treatment of patients with refractory myeloma in the institutes participating in the Japan Myeloma Study Group].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2004;45(6):468-72.
2004: Jun-ichi Nishimura; Yuzuru Kanakura; Russell E Ware; Tsutomu Shichishima; Hideki Nakakuma; Haruhiko Ninomiya; Carlos M DeCastro; Sharon Hall; Akihisa Kanamaru; Keith M Sullivan; Hideaki Mizoguchi; Mitsuhiro Omine; Taroh Kinoshita; Wendell F Rosse
Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan.
Medicine 2004;83(3):193-207.
2004: Junzo Nojima; Hirohiko Kuratsune; Etsuji Suehisa; Teruo Kitani; Yoshinori Iwatani; Yuzuru Kanakura
Strong correlation between the prevalence of cerebral infarction and the presence of anti-cardiolipin/beta2-glycoprotein I and anti-phosphatidylserine/prothrombin antibodies--Co-existence of these antibodies enhances ADP-induced platelet activation in vitro.
Thrombosis and haemostasis 2004;91(5):967-76.
2004: Sadao Hayashi; Kiyoshi Ichihara; Yuzuru Kanakura; Yoshinori Iwatani
A new quality control method based on a moving average of "latent reference values" selected from patients' daily test results.
Rinsho byori. The Japanese journal of clinical pathology 2004;52(3):204-11.
2004: Sachiko Ezoe; Itaru Matsumura; Yusuke Satoh; Hirokazu Tanaka; Yuzuru Kanakura
Cell cycle regulation in hematopoietic stem/progenitor cells.
Cell cycle (Georgetown, Tex.) 2004;3(3):314-8.
2004: Hirohiko Shibayama; Emi Takai; Itaru Matsumura; Michiyoshi Kouno; Eiichi Morii; Yukihiko Kitamura; Junji Takeda; Yuzuru Kanakura
Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis.
The Journal of experimental medicine 2004;199(4):581-92.
2004: Hiroyuki Sugahara; Masao Mizuki; Sayoko Matsumae; Yoshiko Nabetani; Motoko Kikuchi; Yuzuru Kanakura
Footwear exchange has no influence on the incidence of febrile neutropenia in patients undergoing chemotherapy for hematologic malignancies.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2004;25(1):51-4.
2003: Yoshihisa Kataoka; Itaru Matsumura; Sachiko Ezoe; Soichi Nakata; Eri Takigawa; Yusuke Sato; Akira Kawasaki; Takashi Yokota; Koichi Nakajima; Armando Felsani; Yuzuru Kanakura
Reciprocal inhibition between MyoD and STAT3 in the regulation of growth and differentiation of myoblasts.
The Journal of biological chemistry 2003;278(45):44178-87.
2003: Masao Mizuki; Shuji Ueda; Itaru Matsumura; Jun Ishiko; Joachim Schwäble; Hubert Serve; Yuzuru Kanakura
Oncogenic receptor tyrosine kinase in leukemia.
Cellular and molecular biology (Noisy-le-Grand, France) 2003;49(6):907-22.
2003: Susumu Tanaka; Hirohiko Kuratsune; Yoh Hidaka; Yukiko Hakariya; Ke-ita Tatsumi; Toru Takano; Yuzuru Kanakura; Nobuyuki Amino
Autoantibodies against muscarinic cholinergic receptor in chronic fatigue syndrome.
International journal of molecular medicine 2003;12(2):225-30.
2003: Osamu Kabutomori; Yuzuru Kanakura; Yoshinori Iwatani
Incorrect measurement of leukocyte counts in post-bone marrow transplantation (P-BMT) patients.
Annals of hematology 2003;82(8):529-30.
2003: Itaru Matsumura; Hirokazu Tanaka; Yuzuru Kanakura
E2F1 and c-Myc in cell growth and death.
Cell cycle (Georgetown, Tex.) 2003;2(4):333-8.
2003: Hachiro Yamanishi; Shigeru Iyama; Yoshihisa Yamaguchi; Yuzuru Kanakura; Yoshinori Iwatani
Modification of the colorimetric assay for serum unsaturated iron-binding capacity.
Clinical chemistry 2003;49(6 Pt 1):1023-5.
2003: Akira Kawasaki; Itaru Matsumura; Yoshihisa Kataoka; Eri Takigawa; Koichi Nakajima; Yuzuru Kanakura
Opposing effects of PML and PML/RAR alpha on STAT3 activity.
Blood 2003;101(9):3668-73.
2003: Masao Mizuki; Joachim Schwable; Claudia Steur; Chunaram Choudhary; Shuchi Agrawal; Bülent Sargin; Björn Steffen; Itaru Matsumura; Yuzuru Kanakura; Frank-D Böhmer; Carsten Müller-Tidow; Wolfgang E Berdel; Hubert Serve
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.
Blood 2003;101(8):3164-73.
2003: Xian Zhang; Takashi Machii; Itaru Matsumura; Sachiko Ezoe; Akira Kawasaki; Hirokazu Tanaka; Shuji Ueda; Hiroyuki Sugahara; Hirohiko Shibayama; Masao Mizuki; Yuzuru Kanakura
Constitutively activated Rho guanosine triphosphatases regulate the growth and morphology of hairy cell leukemia cells.
International journal of hematology 2003;77(3):263-73.
2003: Shigeki Kimura; Hachiro Yamanishi; Shigeru Iyama; Yoshihisa Yamaguchi; Yuzuru Kanakura
Enzymatic assay for determination of bicarbonate ion in plasma using urea amidolyase.
Clinica chimica acta; international journal of clinical chemistry 2003;328(1-2):179-84.
2003: Koji Hashimoto; Itaru Matsumura; Tohru Tsujimura; Dae-Ki Kim; Hideki Ogihara; Hirokazu Ikeda; Shuji Ueda; Masao Mizuki; Hiroyuki Sugahara; Hirohiko Shibayama; Yukihiko Kitamura; Yuzuru Kanakura
Necessity of tyrosine 719 and phosphatidylinositol 3'-kinase-mediated signal pathway in constitutive activation and oncogenic potential of c-kit receptor tyrosine kinase with the Asp814Val mutation.
Blood 2003;101(3):1094-102.
2003: Yasuki Ueda; Masahiko Matsui; Sadao Hayashi; Yoshihisa Yamaguchi; Yuzuru Kanakura
New homogeneous HDL-cholesterol assay without the influence of high TG sample using the selective detergent to lipoproteins.
Journal of clinical laboratory analysis 2003;17(6):201-8.
2003: Kazuko Tahara; Matsuo Deguchi; Masanori Kagita; Takashi Nakano; Kaori Ichigo; Yuko Sasahara; Seishi Asari; Yuzuru Kanakura; Yoshinori Iwatani
[Clinical evaluation of polymerase chain reaction (PCR) method for the detection of hepatitis B virus (HBV)-DNA].
Rinshō Biseibutsu Jinsoku Shindan Kenkyūkai shi = JARMAM : Journal of the Association for Rapid Method and Automation in Microbiology 2003;13(2):121-8.
2003: Osamu Kabutomori; Yuzuru Kanakura; Yoshinori Iwatani
Marked decreases of total and immature reticulocytes in myelodysplastic syndrome among patients with pancytopenia.
Acta haematologica 2003;109(4):212-3.
2003: Shigeki Kimura; Shigeru Iyama; Yoshihisa Yamaguchi; Yuzuru Kanakura
New enzymatic assay for serum urea nitrogen using urea amidolyase.
Journal of clinical laboratory analysis 2003;17(2):52-6.
2003: Hachiro Yamanishi; Shigeru Iyama; Yoshihisa Yamaguchi; Yuzuru Kanakura; Yoshinori Iwatani
Total iron-binding capacity calculated from serum transferrin concentration or serum iron concentration and unsaturated iron-binding capacity.
Clinical chemistry 2003;49(1):175-8.
2002: Shuji Ueda; Hirokazu Ikeda; Masao Mizuki; Jun Ishiko; Itaru Matsumura; Hirokazu Tanaka; Hirohiko Shibayama; Hiroyuki Sugahara; Emi Takai; Xian Zhang; Takashi Machii; Yuzuru Kanakura
Constitutive activation of c-kit by the juxtamembrane but not the catalytic domain mutations is inhibited selectively by tyrosine kinase inhibitors STI571 and AG1296.
International journal of hematology 2002;76(5):427-35.
2002: Sachiko Ezoe; Itaru Matsumura; Soichi Nakata; Karin Gale; Katsuhiko Ishihara; Naoko Minegishi; Takashi Machii; Toshio Kitamura; Masayuki Yamamoto; Tariq Enver; Yuzuru Kanakura
GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through accumulation of p21(WAF1) and p27(Kip1) proteins.
Blood 2002;100(10):3512-20.
2002: Junzo Nojima; Hirohiko Kuratsune; Etsuji Suehisa; Tomio Kawasaki; Takashi Machii; Teruo Kitani; Yoshinori Iwatani; Yuzuru Kanakura
Acquired activated protein C resistance associated with anti-protein S antibody as a strong risk factor for DVT in non-SLE patients.
Thrombosis and haemostasis 2002;88(5):716-22.
2002: Hirohiko Kuratsune; Kouzi Yamaguti; Gudrun Lindh; Birgitta Evengård; Gisela E Hagberg; Kiyoshi Matsumura; Masao Iwase; Hirotaka Onoe; Mamoru Takahashi; Takashi Machii; Yuzuru Kanakura; Teruo Kitani; Bengt Långström; Yasuyoshi Watanabe
Brain regions involved in fatigue sensation: reduced acetylcarnitine uptake into the brain.
NeuroImage 2002;17(3):1256-65.
2002: Hachiro Yamanishi; Shigeru Iyama; Yoshihisa Yamaguchi; Yuzuru Kanakura; Yoshinori Iwatani
Relation between iron content of serum ferritin and clinical status factors extracted by factor analysis in patients with hyperferritinemia.
Clinical biochemistry 2002;35(7):523-9.
2002: Osamu Kabutomori; Yuzuru Kanakura; Yoshinori I Watani
Induction of toxic granulation in neutrophils by granulocyte colony-stimulating factor.
European journal of haematology 2002;69(3):187-8.
2002: Hachiro Yamanishi; Shigeru Iyama; Yoshihisa Yamaguchi; Yuzuru Kanakura; Yoshinori Iwatani
Modification of fully automated total iron-binding capacity (TIBC) assay in serum and comparison with dimension TIBC method.
Clinical chemistry 2002;48(9):1565-70.
2002: Junzo Nojima; Hirohiko Kuratsune; Etsuji Suehisa; Tomio Kawasaki; Takashi Machii; Teruo Kitani; Yoshinori Iwatani; Yuzuru Kanakura
Acquired activated protein C resistance is associated with the co-existence of anti-prothrombin antibodies and lupus anticoagulant activity in patients with systemic lupus erythematosus.
British journal of haematology 2002;118(2):577-83.
2002: Itaru Matsumura; Yuzuru Kanakura
Molecular control of megakaryopoiesis and thrombopoiesis.
International journal of hematology 2002;75(5):473-83.
2002: Hirokazu Tanaka; Itaru Matsumura; Sachiko Ezoe; Yusuke Satoh; Toshiyuki Sakamaki; Chris Albanese; Takashi Machii; Richard G Pestell; Yuzuru Kanakura
E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination.
Molecular cell 2002;9(5):1017-29.
2002: Osamu Kabutomori; Yuzuru Kanakura; Yoshinori Iwatani
Movement of toxic granulation neutrophils and C-reactive protein in inflammatory processes.
The American journal of medicine 2002;112(7):595-6.
2002: Shuji Ueda; Masao Mizuki; Hirokazu Ikeda; Tohru Tsujimura; Itaru Matsumura; Kazushi Nakano; Hanako Daino; Zen-ichiro Honda Zi; Junko Sonoyama; Hirohiko Shibayama; Hiroyuki Sugahara; Takashi Machii; Yuzuru Kanakura
Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: contribution of src family kinase and PI3-kinase on calcium mobilization and cell migration.
Blood 2002;99(9):3342-9.
2002: Jun-ichi Nishimura Ji; Toshiyuki Hirota; Yuzuru Kanakura; Takashi Machii; Takashi Kageyama; Shoichi Doi; Hiroshi Wada; Toru Masaoka; Yoshio Kanayama; Hiroshi Fujii; Norimitsu Inoue; Maki Kuwayama; Norimitsu Inoue; Kazuhito Ohishi; Taroh Kinoshita
Long-term support of hematopoiesis by a single stem cell clone in patients with paroxysmal nocturnal hemoglobinuria.
Blood 2002;99(8):2748-51.
2002: Masao Mizuki; Itaru Matsumura; Hirokazu Ikeda; Shuji Ueda; Junko Sonoyama; Junko Okashima; Yuzuru Kanakura
[Inhibition of leukemogenic signaling and its therapeutic implications].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2002;43(4):239-42.
2002: Junko Sonoyama; Itaru Matsumura; Sachiko Ezoe; Yusuke Satoh; Xian Zhang; Yoshihisa Kataoka; Emi Takai; Masao Mizuki; Takashi Machii; Hiroshi Wakao; Yuzuru Kanakura
Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells.
The Journal of biological chemistry 2002;277(10):8076-82.
2001: Yuzuru Kanakura; Itaru Matsumura
[Signal transduction from receptors for hematopoietic growth factors].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(12):2304-7.
2001: Osamu Kabutomori; Yuzuru Kanakura; Yoshinori Iwatani
Increase in platelet-large cell ratio in chronic myeloid leukemia.
Leukemia research 2001;25(10):873.
2001: Junzo Nojima; Hirohiko Kuratsune; Etsuji Suehisa; Yoshiaki Futsukaichi; Hachiro Yamanishi; Takashi Machii; Teruo Kitani; Yoshinori Iwatani; Yuzuru Kanakura
Anti-prothrombin antibodies combined with lupus anti-coagulant activity is an essential risk factor for venous thromboembolism in patients with systemic lupus erythematosus.
British journal of haematology 2001;114(3):647-54.
2001: Junzo Nojima; Hirohiko Kuratsune; Etsuji Suehisa; Yoshiaki Futsukaichi; Hachiro Yamanishi; Takashi Machii; Yoshinori Iwatani; Yuzuru Kanakura
Association between the prevalence of antibodies to beta(2)-glycoprotein I, prothrombin, protein C, protein S, and annexin V in patients with systemic lupus erythematosus and thrombotic and thrombocytopenic complications.
Clinical chemistry 2001;47(6):1008-15.
2001: Kenneth L Phillips; Russell E Ware; S Hall; L Wilson; Tracy Gentry; Thad A Howard; Y Murakami; Makio Shibano; Takashi Machii; Eli Gilboa; Yuzuru Kanakura; J Takeda; Taroh Kinoshita; Wendell F Rosse; Clay A Smith
Efficient retrovirus-mediated PIG-A gene transfer and stable restoration of GPI-anchored protein expression in cells with the PNH phenotype.
Blood 2001;97(10):3004-10.
2001: M Tatsumi; H Kitayama; Hiroyuki Sugahara; N Tokita; H Nakamura; Yuzuru Kanakura; Tsunehiko Nishimura
Whole-body hybrid PET with 18F-FDG in the staging of non-Hodgkin's lymphoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(4):601-8.
2001: Sadao Hayashi; Etsuji Suehisa; Seishi Asari; I Maeda; Isao Nishi; Yoshinori Iwatani; Yuzuru Kanakura
[Informed consent for the use of the remaining portion of laboratory specimens for education, research, and quality control of laboratory tests].
Rinsho byori. The Japanese journal of clinical pathology 2001;49(3):273-7.
2001: Etsuji Suehisa; T Nomura; T Kawasaki; Yuzuru Kanakura
Frequency of natural coagulation inhibitor (antithrombin III, protein C and protein S) deficiencies in Japanese patients with spontaneous deep vein thrombosis.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2001;12(2):95-9.
2001: Akira Kawasaki; Itaru Matsumura; Sachiko Ezoe; Hiromitsu Tanaka; Y Terada; M Tatsuka; Takashi Machii; H Miyazaki; Y Furukawa; Yuzuru Kanakura
Downregulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells.
The Journal of cell biology 2001;152(2):275-87.
2001: Shigeki Kimura; Shigeru Iyama; Yoshihisa Yamaguchi; Yuzuru Kanakura
Homogenous enzyme immunoassay for cyclosporine in whole blood using the EMIT 2000 cyclosporine specific assay with the COBAS MIRA-plus analyzer.
Journal of clinical laboratory analysis 2001;15(6):319-23.
2001: Etsuji Suehisa; M Toku; T Kawasaki; Yuzuru Kanakura
Measurement of a newly developed thrombomodulin addition activated partial thromboplastin time assay in patients with deep venous thrombosis.
Haemostasis 2001;31(1):26-31.
2000: Masao Mizuki; R Fenski; Hartmut Halfter; Itaru Matsumura; R Schmidt; C Müller; W Grüning; K Kratz-Albers; S Serve; Claudia Steur; Thomas Büchner; Joachim Kienast; Yuzuru Kanakura; Wolfgang E Berdel; Hubert Serve
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways.
Blood 2000;96(12):3907-14.
2000: Osamu Kabutomori; Yoshinori Iwatani; Yuzuru Kanakura; O Kabutomuri
Toxic granulation neutrophils and C-reactive protein.
Archives of internal medicine 2000;160(21):3326-7.
2000: Y Kuwahara; A Hirata; H Miwa; S Munakata; Shuji Ueda; Yuzuru Kanakura; M Maruno; Tadashi Hongyo; Taisei Nomura; Katsuyuki Aozasa
Epstein-Barr virus associated B-cell lymphoma of brain developing in myelodysplastic syndrome with c-kit mutation (Try-557 -->stop).
American journal of hematology 2000;65(3):234-8.
2000: Itaru Matsumura; Akira Kawasaki; Hiromitsu Tanaka; Junko Sonoyama; Sachiko Ezoe; Naoko Minegishi; Koichi Nakajima; Masahiro Yamamoto; Yuzuru Kanakura
Biologic significance of GATA-1 activities in Ras-mediated megakaryocytic differentiation of hematopoietic cell lines.
Blood 2000;96(7):2440-50.
2000: Junko Odajima; Itaru Matsumura; Junko Sonoyama; Hanako Daino; Akira Kawasaki; Hiromitsu Tanaka; Naohiro Inohara; Toshio Kitamura; J Downward; Koichi Nakajima; Toshio Hirano; Yuzuru Kanakura
Full oncogenic activities of v-Src are mediated by multiple signaling pathways. Ras as an essential mediator for cell survival.
The Journal of biological chemistry 2000;275(31):24096-105.
2000: M Yamaguchi; Takashi Machii; Y Azenishi; Jun-ichi Nishimura; Makio Shibano; Yuzuru Kanakura; Teruo Kitani
Detection of small populations of CD59-deficient erythrocytes in patients with aplastic anemia or myelodysplastic syndrome and normal individuals.
Blood cells, molecules & diseases 2000;26(3):247-54.
2000: Tadashi Hongyo; T Li; Mukh Syaifudin; R Baskar; Hirokazu Ikeda; Yuzuru Kanakura; Katsuyuki Aozasa; Taisei Nomura
Specific c-kit mutations in sinonasal natural killer/T-cell lymphoma in China and Japan.
Cancer research 2000;60(9):2345-7.
2000: Hanako Daino; Itaru Matsumura; K Takada; Junko Odajima; Hiromitsu Tanaka; Shuji Ueda; Hirohiko Shibayama; Hirokazu Ikeda; Masahiko Hibi; Takashi Machii; Toshio Hirano; Yuzuru Kanakura
Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells.
Blood 2000;95(8):2577-85.
2000: Itaru Matsumura; Hiromitsu Tanaka; Akira Kawasaki; Junko Odajima; Hanako Daino; Keiko Hashimoto; Hiroshi Wakao; Koichi Nakajima; Takayuki Kato; H Miyazaki; Yuzuru Kanakura
Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line.
The Journal of biological chemistry 2000;275(8):5553-9.
2000: Hiromitsu Tanaka; Itaru Matsumura; Koichi Nakajima; Hanako Daino; Junko Sonoyama; Hitoshi Yoshida; Kenji Oritani; Takashi Machii; Masahiro Yamamoto; Toshio Hirano; Yuzuru Kanakura
GATA-1 blocks IL-6-induced macrophage differentiation and apoptosis through the sustained expression of cyclin D1 and bcl-2 in a murine myeloid cell line M1.
Blood 2000;95(4):1264-73.
2000: Maki Kuwayama; Takashi Machii; M Yamaguchi; Kouzi Yamaguti; Teruo Kitani; Yuzuru Kanakura
Blastic transformation of splenic lymphoma with villous lymphocytes after a well-controlled chronic phase of more than 10 years.
International journal of hematology 2000;71(2):167-71.
1999: K Aoyama; Kenji Oritani; Takashi Yokota; Jun Ishikawa; Tetsuo Nishiura; K Miyake; Yuzuru Kanakura; Yoshiaki Tomiyama; Paul W Kincade; Yuji Matsuzawa
Stromal cell CD9 regulates differentiation of hematopoietic stem/progenitor cells.
Blood 1999;93(8):2586-94.
1999: Junzo Nojima; Etsuji Suehisa; Hirohiko Kuratsune; Takashi Machii; T Koike; Teruo Kitani; Yuzuru Kanakura; N Amino
Platelet activation induced by combined effects of anticardiolipin and lupus anticoagulant IgG antibodies in patients with systemic lupus erythematosus--possible association with thrombotic and thrombocytopenic complications.
Thrombosis and haemostasis 1999;81(3):436-41.
1999: Itaru Matsumura; Toshio Kitamura; Hiroshi Wakao; Hiromitsu Tanaka; Keiko Hashimoto; C Albanese; J Downward; Richard G Pestell; Yuzuru Kanakura
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells.
The EMBO journal 1999;18(5):1367-77.
1999: Kenji Oritani; Yoshiaki Tomiyama; Paul W Kincade; K Aoyama; Takashi Yokota; Itaru Matsumura; Yuzuru Kanakura; Koichi Nakajima; Toshio Hirano; Yuji Matsuzawa
Both Stat3-activation and Stat3-independent BCL2 downregulation are important for interleukin-6-induced apoptosis of 1A9-M cells.
Blood 1999;93(4):1346-54.
1999: Tohru Tsujimura; Keiko Hashimoto; H Kitayama; Hirokazu Ikeda; Hiroyuki Sugahara; Itaru Matsumura; Tsuneyasu Kaisho; N Terada; Yukihiko Kitamura; Yuzuru Kanakura
Activating mutation in the catalytic domain of c-kit elicits hematopoietic transformation by receptor self-association not at the ligand-induced dimerization site.
Blood 1999;93(4):1319-29.
1999: Itaru Matsumura; Y Horikawa; Yuzuru Kanakura
Functional roles of thrombopoietin-c-mpl system in essential thrombocythemia.
Leukemia & lymphoma 1999;32(3-4):351-8.
1998: Hitoshi Yoshida; Tetsuo Nishiura; Takahiro Karasuno; Itaru Matsumura; Jun Ishikawa; M Yoshimura; Takashi Yokota; Y Okajima; Minetaro Ogawa; Yuzuru Kanakura; Yoshiaki Tomiyama; Yuji Matsuzawa
Effect of the interaction between fibronectin and VLA-4 on the proliferation of human B cells, especially a novel human B-cell line, OPM-3.
British journal of haematology 1998;103(3):804-12.
1998: Masao Mizuki; Shuji Ueda; S Tagawa; Hirohiko Shibayama; Y Nishimori; Makio Shibano; Hideo Asada; Masato Tanaka; Shigekazu Nagata; U Koudera; K Suzuki; Takashi Machii; M Ohsawa; Katsuyuki Aozasa; Teruo Kitani; Yuzuru Kanakura
Natural killer cell-derived large granular lymphocyte lymphoma of lung developed in a patient with hypersensitivity to mosquito bites and reactivated Epstein-Barr virus infection.
American journal of hematology 1998;59(4):309-15.
1998: Masamichi Shiraga; Yoshiaki Tomiyama; S Honda; H Suzuki; Satoru Kosugi; Seiji Tadokoro; Yuzuru Kanakura; K Tanoue; Yoshiyuki Kurata; Yuji Matsuzawa
Involvement of Na+/Ca2+ exchanger in inside-out signaling through the platelet integrin IIbbeta3.
Blood 1998;92(10):3710-20.
1998: Minetaro Ogawa; Tetsuo Nishiura; M Yoshimura; Y Horikawa; Hitoshi Yoshida; Y Okajima; Itaru Matsumura; Jun Ishikawa; H Nakao; Yoshiaki Tomiyama; Y Kanayama; Yuzuru Kanakura; Yuji Matsuzawa
Decreased nitric oxide-mediated natural killer cell activation in chronic fatigue syndrome.
European journal of clinical investigation 1998;28(11):937-43.
1998: Seiji Tadokoro; Yoshiaki Tomiyama; Shigenori Honda; M Arai; Naoko Yamamoto; Masamichi Shiraga; Satoru Kosugi; Yuzuru Kanakura; Yoshiyuki Kurata; Yuji Matsuzawa
A Gln747-->Pro substitution in the IIb subunit is responsible for a moderate IIbbeta3 deficiency in Glanzmann thrombasthenia.
Blood 1998;92(8):2750-8.
1998: Dae-Ki Kim; Eiichi Morii; Hideki Ogihara; Keiko Hashimoto; Kenji Oritani; YM Lee; Tomoko Jippo; S Adachi; Yuzuru Kanakura; Yukihiko Kitamura
Impaired expression of integrin alpha-4 subunit in cultured mast cells derived from mutant mice of mi/mi genotype.
Blood 1998;92(6):1973-80.
1998: Y Okajima; Itaru Matsumura; Tetsuo Nishiura; Keiko Hashimoto; Hitoshi Yoshida; Jun Ishikawa; Hiroshi Wakao; A Yoshimura; Yuzuru Kanakura; Yoshiaki Tomiyama; Yuji Matsuzawa
Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5.
The Journal of biological chemistry 1998;273(36):22877-83.
1998: T Nishida; S Hirota; M Taniguchi; K Hashimoto; Koji Isozaki; H Nakamura; Yuzuru Kanakura; T Tanaka; Arimichi Takabayashi; H Matsuda; Y Kitamura
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene.
Nature genetics 1998;19(4):323-4.
1998: Hirohiko Kuratsune; Kouzi Yamaguti; Gudrun Lindh; B Evengard; Mamoru Takahashi; Takashi Machii; Kiyoshi Matsumura; J Takaishi; S Kawata; Bengt Långström; Yuzuru Kanakura; Teruo Kitani; Yasuyoshi Watanabe
Low levels of serum acylcarnitine in chronic fatigue syndrome and chronic hepatitis type C, but not seen in other diseases.
International journal of molecular medicine 1998;2(1):51-6.
1998: Itaru Matsumura; Koichi Nakajima; Hiroshi Wakao; S Hattori; Keiko Hashimoto; Hiroyuki Sugahara; Takayuki Kato; H Miyazaki; T Hirano; Yuzuru Kanakura
Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line.
Molecular and cellular biology 1998;18(7):4282-90.
1998: Junzo Nojima; Etsuji Suehisa; Hirohiko Kuratsune; Takashi Machii; M Toku; H Tada; Kouzi Yamaguti; T Koike; Yuzuru Kanakura; Teruo Kitani; N Amino
High prevalence of thrombocytopenia in SLE patients with a high level of anticardiolipin antibodies combined with lupus anticoagulant.
American journal of hematology 1998;58(1):55-60.
1998: M Yoshimura; Y Ihara; Tetsuo Nishiura; Y Okajima; Minetaro Ogawa; Hitoshi Yoshida; M Suzuki; K Yamamura; Yuzuru Kanakura; Yuji Matsuzawa; Naoyuki Taniguchi
Bisecting GlcNAc structure is implicated in suppression of stroma-dependent haemopoiesis in transgenic mice expressing N-acetylglucosaminyltransferase III.
The Biochemical journal 1998;331 ( Pt 3)():733-42.
1998: Takashi Yokota; Kenji Oritani; H Mitsui; K Aoyama; Jun Ishikawa; Hiroyuki Sugahara; Itaru Matsumura; Schickwann Tsai; Yoshiaki Tomiyama; Yuzuru Kanakura; Yuji Matsuzawa
Growth-supporting activities of fibronectin on hematopoietic stem/progenitor cells in vitro and in vivo: structural requirement for fibronectin activities of CS1 and cell-binding domains.
Blood 1998;91(9):3263-72.
1998: M Morimoto; Tohru Tsujimura; Yuzuru Kanakura; Yukihiko Kitamura; Hikaru Matsuda
Expression of c-kit and stem cell factor mRNA in liver specimens from healthy adult dogs.
American journal of veterinary research 1998;59(3):363-6.
1998: Seiichi Hirota; Koji Isozaki; Y Moriyama; Keiko Hashimoto; Toshirou Nishida; Shingo Ishiguro; K Kawano; M Hanada; A Kurata; M Takeda; G Muhammad Tunio; Y Matsuzawa; Yuzuru Kanakura; Yasuhisa Shinomura; Yukihiko Kitamura
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
Science (New York, N.Y.) 1998;279(5350):577-80.
1998: Hirohiko Kuratsune; Kouzi Yamaguti; M Sawada; S Kodate; Takashi Machii; Yuzuru Kanakura; Teruo Kitani
Dehydroepiandrosterone sulfate deficiency in chronic fatigue syndrome.
International journal of molecular medicine 1998;1(1):143-6.
1998: Masao Mizuki; Yuzuru Kanakura
[Small noncleaved cell lymphoma, non-Burkitt's type].
Ryōikibetsu shōkōgun shirīzu 1998;(22 Pt 3):265-7.
1998: Masao Mizuki; Yuzuru Kanakura
[Small noncleaved cell lymphoma, Burkitt's type].
Ryōikibetsu shōkōgun shirīzu 1998;(22 Pt 3):262-4.
1997: Y Horikawa; Itaru Matsumura; Keiko Hashimoto; Masamichi Shiraga; Satoru Kosugi; Seiji Tadokoro; Takayuki Kato; H Miyazaki; Yoshiaki Tomiyama; Yoshiyuki Kurata; Yuji Matsuzawa; Yuzuru Kanakura
Markedly reduced expression of platelet c-mpl receptor in essential thrombocythemia.
Blood 1997;90(10):4031-8.
1997: Tohru Tsujimura; Keiko Hashimoto; Eiichi Morii; G M Tunio; K Tsujino; T Kondo; Yuzuru Kanakura; Yukihiko Kitamura
Involvement of transcription factor encoded by the mouse mi locus (MITF) in apoptosis of cultured mast cells induced by removal of interleukin-3.
The American journal of pathology 1997;151(4):1043-51.
1997: Itaru Matsumura; Jun Ishikawa; Koichi Nakajima; Kenji Oritani; Yoshiaki Tomiyama; Jun-ichiro Miyagawa; Takayuki Kato; H Miyazaki; Yuji Matsuzawa; Yuzuru Kanakura
Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5.
Molecular and cellular biology 1997;17(5):2933-43.
1997: Tohru Tsujimura; Yuzuru Kanakura; Yukihiko Kitamura
Mechanisms of constitutive activation of c-kit receptor tyrosine kinase.
Leukemia 1997;11 Suppl 3():396-8.
1996: Itaru Matsumura; H Ikeda; Yuzuru Kanakura
The effects of thrombopoietin on the growth of acute myeloblastic leukemia cells.
Leukemia & lymphoma 1996;23(5-6):533-8.
1996: Tetsuo Nishiura; T Karasuno; H Yoshida; H Nakao; M Ogawa; Y Horikawa; M Yoshimura; Y Okajima; Yuzuru Kanakura; Y Kanayama; Yuji Matsuzawa
Functional role of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor in cell adhesion and proliferation of a human myeloma cell line OPM-2.
Blood 1996;88(9):3546-54.
1996: Itaru Matsumura; Yuzuru Kanakura; Takayuki Kato; H Ikeda; Y Horikawa; Jun Ishikawa; H Kitayama; Tetsuo Nishiura; Yoshiaki Tomiyama; H Miyazaki; Yuji Matsuzawa
The biologic properties of recombinant human thrombopoietin in the proliferation and megakaryocytic differentiation of acute myeloblastic leukemia cells.
Blood 1996;88(8):3074-82.
1996: Masamichi Shiraga; Yoshiaki Tomiyama; Shigenori Honda; H Kashiwagi; Satoru Kosugi; M Handa; Y Ikeda; Yuzuru Kanakura; Yoshiyuki Kurata; Yuji Matsuzawa
Affinity modulation of the platelet integrin alpha IIb beta 3 by alpha-chymotrypsin: a possible role for Na+/Ca2+ exchanger.
Blood 1996;88(7):2594-602.
1996: T Tsujimura; Eiichi Morii; M Nozaki; Keiko Hashimoto; Yoshinori Moriyama; K Takebayashi; T Kondo; Yuzuru Kanakura; Y Kitamura
Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of mice.
Blood 1996;88(4):1225-33.
1996: H Kitayama; T Tsujimura; Itaru Matsumura; Kenji Oritani; H Ikeda; Jun Ishikawa; Masaru Okabe; M Suzuki; K Yamamura; Yuji Matsuzawa; Y Kitamura; Yuzuru Kanakura
Neoplastic transformation of normal hematopoietic cells by constitutively activating mutations of c-kit receptor tyrosine kinase.
Blood 1996;88(3):995-1004.
1996: H Kashiwagi; Yoshiaki Tomiyama; S Nozaki; Shigenori Honda; Satoru Kosugi; Masamichi Shiraga; T Nakagawa; N Nagao; Yuzuru Kanakura; Yoshiyuki Kurata; Yuji Matsuzawa
A single nucleotide insertion in codon 317 of the CD36 gene leads to CD36 deficiency.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(8):1026-32.
1996: Satoru Kosugi; Yoshiyuki Kurata; Yoshiaki Tomiyama; T Tahara; Takayuki Kato; Seiji Tadokoro; Masamichi Shiraga; Shigenori Honda; Yuzuru Kanakura; Yuji Matsuzawa
Circulating thrombopoietin level in chronic immune thrombocytopenic purpura.
British journal of haematology 1996;93(3):704-6.
1996: Yoshinori Moriyama; T Tsujimura; Keiko Hashimoto; M Morimoto; H Kitayama; Y Kitamura; Yuzuru Kanakura
Role of aspartic acid 814 in the function and expression of c-kit receptor tyrosine kinase.
The Journal of biological chemistry 1996;271(7):3347-50.
1996: Satoru Kosugi; Yoshiaki Tomiyama; Masamichi Shiraga; H Kashiwagi; H Mizutani; Yuzuru Kanakura; Yoshiyuki Kurata; Yuji Matsuzawa
Platelet-associated anti-glycoprotein (GP) IIb-IIIa autoantibodies in chronic immune thrombocytopenic purpura mainly recognize cation-dependent conformations: comparison with the epitopes of serum autoantibodies.
Thrombosis and haemostasis 1996;75(2):339-45.
1996: M Yoshimura; Y Ihara; A Ohnishi; Naokuni Ijuhin; Tetsuo Nishiura; Yuzuru Kanakura; Yuji Matsuzawa; Naoyuki Taniguchi
Bisecting N-acetylglucosamine on K562 cells suppresses natural killer cytotoxicity and promotes spleen colonization.
Cancer research 1996;56(2):412-8.
1996: Itaru Matsumura; Yuzuru Kanakura; H Ikeda; Jun Ishikawa; H Yoshida; Y Horikawa; Tetsuo Nishiura; T Tahara; Takayuki Kato; H Miyazaki; Yuji Matsuzawa
Coexpression of thrombopoietin and c-mpl genes in human acute myeloblastic leukemia cells.
Leukemia 1996;10(1):91-4.
1996: T Tsujimura; M Morimoto; Keiko Hashimoto; Yoshinori Moriyama; H Kitayama; Yuji Matsuzawa; Y Kitamura; Yuzuru Kanakura
Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain.
Blood 1996;87(1):273-83.
1996: Keiko Hashimoto; T Tsujimura; Yoshinori Moriyama; Atsushi Yamatodani; M Kimura; K Tohya; M Morimoto; H Kitayama; Yuzuru Kanakura; Y Kitamura
Transforming and differentiation-inducing potential of constitutively activated c-kit mutant genes in the IC-2 murine interleukin-3-dependent mast cell line.
The American journal of pathology 1996;148(1):189-200.
1995: A Ito; S Hirota; H Mizuno; Y Kawasaki; T Takemura; Tetsuo Nishiura; Yuzuru Kanakura; Y Katayama; Shintaro Nomura; Y Kitamura
Expression of vascular permeability factor (VPF/VEGF) messenger RNA by plasma cells: possible involvement in the development of edema in chronic inflammation.
Pathology international 1995;45(10):715-20.
1995: H Mizutani; Yoshiyuki Kurata; Satoru Kosugi; Masamichi Shiraga; H Kashiwagi; Yoshiaki Tomiyama; Yuzuru Kanakura; R A Good; Y Matsuzawa
Monoclonal anticardiolipin autoantibodies established from the (New Zealand white x BXSB)F1 mouse model of antiphospholipid syndrome cross-react with oxidized low-density lipoprotein.
Arthritis and rheumatism 1995;38(10):1382-8.
1995: H Kashiwagi; Yoshiaki Tomiyama; Satoru Kosugi; Masamichi Shiraga; Robert Lipsky; N Nagao; Yuzuru Kanakura; Yoshiyuki Kurata; Yuji Matsuzawa
Family studies of type II CD36 deficient subjects: linkage of a CD36 allele to a platelet-specific mRNA expression defect(s) causing type II CD36 deficiency.
Thrombosis and haemostasis 1995;74(2):758-63.
1995: Itaru Matsumura; Yuzuru Kanakura; Takayuki Kato; H Ikeda; Jun Ishikawa; Y Horikawa; Keiko Hashimoto; Yoshinori Moriyama; T Tsujimura; Tetsuo Nishiura
Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin.
Blood 1995;86(2):703-9.
1995: Y Kitamura; T Tsujimura; Tomoko Jippo; T Kasugai; Yuzuru Kanakura
Regulation of development, survival and neoplastic growth of mast cells through the c-kit receptor.
International archives of allergy and immunology 1995;107(1-3):54-6.
1995: T Tsujimura; T Furitsu; M Morimoto; Y Kanayama; Shintaro Nomura; Yuji Matsuzawa; Y Kitamura; Yuzuru Kanakura
Substitution of an aspartic acid results in constitutive activation of c-kit receptor tyrosine kinase in a rat tumor mast cell line RBL-2H3.
International archives of allergy and immunology 1995;106(4):377-85.
1995: H Kitayama; Yuzuru Kanakura; T Furitsu; T Tsujimura; Kenji Oritani; H Ikeda; Hiroyuki Sugahara; H Mitsui; Y Kanayama; Y Kitamura
Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines.
Blood 1995;85(3):790-8.
1995: K Hashimoto; Yuzuru Kanakura; H Yagura; H Mitsui; M Ogawa; Y Horikawa; Tetsuo Nishiura; Y Kanayama; Yuji Matsuzawa
Early trilineage recovery by granulocyte colony-stimulating factor in a patient with aplastic anemia.
Acta haematologica 1995;93(2-4):110-2.
1994: Hiroyuki Sugahara; Yuzuru Kanakura; T Furitsu; K Ishihara; Kenji Oritani; H Ikeda; H Kitayama; Jun Ishikawa; Keiko Hashimoto; Y Kanayama
Induction of programmed cell death in human hematopoietic cell lines by fibronectin via its interaction with very late antigen 5.
The Journal of experimental medicine 1994;179(6):1757-66.
1994: T Tsujimura; T Furitsu; M Morimoto; Koji Isozaki; Shintaro Nomura; Yuji Matsuzawa; Y Kitamura; Yuzuru Kanakura
Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation.
Blood 1994;83(9):2619-26.
1994: Yuzuru Kanakura; T Furitsu; T Tsujimura; J H Butterfield; L K Ashman; H Ikeda; H Kitayama; Y Kanayama; Yuji Matsuzawa; Y Kitamura
Activating mutations of the c-kit proto-oncogene in a human mast cell leukemia cell line.
Leukemia 1994;8 Suppl 1():S18-22.
1994: Uichi Koshimizu; T Tsujimura; Koji Isozaki; Shintaro Nomura; T Furitsu; Yuzuru Kanakura; Y Kitamura; Yoshitake Nishimune
Wn mutation of c-kit receptor affects its post-translational processing and extracellular expression.
Oncogene 1994;9(1):157-62.
1993: H Ikeda; Yuzuru Kanakura; T Furitsu; H Kitayama; Hiroyuki Sugahara; Tetsuo Nishiura; T Karasuno; Yoshiaki Tomiyama; Atsushi Yamatodani; Y Kanayama
Changes in phenotype and proliferative potential of human acute myeloblastic leukemia cells in culture with stem cell factor.
Experimental hematology 1993;21(13):1686-94.
1993: M Morimoto; T Kasugai; H Tei; T Jippo-Kanemoto; Yuzuru Kanakura; Y Kitamura
Age-dependent amelioration of hypoplastic anemia in Ws/Ws rats with a small deletion at the kinase domain of c-kit.
Blood 1993;82(11):3315-20.
1993: T Hirata; Eiichi Morii; M Morimoto; T Kasugai; T Tsujimura; S Hirota; Yuzuru Kanakura; Shintaro Nomura; Y Kitamura
Stem cell factor induces outgrowth of c-kit-positive neurites and supports the survival of c-kit-positive neurons in dorsal root ganglia of mouse embryos.
Development (Cambridge, England) 1993;119(1):49-56.
1993: T Tsujimura; Uichi Koshimizu; H Katoh; Koji Isozaki; Yuzuru Kanakura; T Tono; S Adachi; T Kasugai; H Tei; Yoshitake Nishimune
Mast cell number in the skin of heterozygotes reflects the molecular nature of c-kit mutation.
Blood 1993;81(10):2530-8.
1993: Yuzuru Kanakura; H Ikeda; H Kitayama; Hiroyuki Sugahara; T Furitsu
Expression, function and activation of the proto-oncogene c-kit product in human leukemia cells.
Leukemia & lymphoma 1993;10(1-2):35-41.
1993: Yuzuru Kanakura; Hiroyuki Sugahara; H Mitsui; H Ikeda; T Furitsu; H Yagura; H Kitayama; Y Kanayama; Yuji Matsuzawa
Functional expression of interleukin 2 receptor in a human factor-dependent megakaryoblastic leukemia cell line: evidence that granulocyte-macrophage colony-stimulating factor inhibits interleukin 2 binding to its receptor.
Cancer research 1993;53(3):675-80.
1992: Y Ebi; Yuzuru Kanakura; T Jippo-Kanemoto; T Tsujimura; T Furitsu; H Ikeda; S Adachi; T Kasugai; Shintaro Nomura; Y Kanayama
Low c-kit expression of cultured mast cells of mi/mi genotype may be involved in their defective responses to fibroblasts that express the ligand for c-kit.
Blood 1992;80(6):1454-62.
1992: T Tamaki; Yuzuru Kanakura; A Kuriu; H Ikeda; H Mitsui; H Yagura; Itaru Matsumura; Brian J Druker; James D Griffin; Y Kanayama
Surface immunoglobulin-mediated signal transduction involves rapid phosphorylation and activation of the protooncogene product Raf-1 in human B-cells.
Cancer research 1992;52(3):566-70.
1991: H Ikeda; Yuzuru Kanakura; T Tamaki; A Kuriu; H Kitayama; Jun Ishikawa; Y Kanayama; T Yonezawa; S Tarui; James D Griffin
Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells.
Blood 1991;78(11):2962-8.
1991: A Kuriu; H Ikeda; Yuzuru Kanakura; James D Griffin; Brian J Druker; H Yagura; H Kitayama; Jun Ishikawa; Tetsuo Nishiura; Y Kanayama
Proliferation of human myeloid leukemia cell line associated with the tyrosine-phosphorylation and activation of the proto-oncogene c-kit product.
Blood 1991;78(11):2834-40.
1991: H Mitsui; H Yagura; T Tamaki; H Ikeda; Itaru Matsumura; Yuzuru Kanakura; T Yonezawa; S Tarui; H Ideka
High-affinity interleukin 2 receptors on B cell chronic lymphocytic leukemia cells are induced by phorbol myristate acetate but not by calcium ionophore.
Immunology letters 1991;27(2):105-11.
1990: T Fukuzumi; N Waki; Yuzuru Kanakura; J Nagoshi; S Hirota; Kunihiko Yoshikawa; Y Kitamura
Differences in irradiation susceptibility and turnover between mucosal and connective tissue-type mast cells of mice.
Experimental hematology 1990;18(7):843-7.
1990: N Waki; Y Kitamura; Yuzuru Kanakura; H Asai; Toru Nakano
Intraperitoneally injected cultured mast cells suppress recruitment and differentiation of bone marrow-derived mast cell precursors in the peritoneal cavity of W/Wv mice.
Experimental hematology 1990;18(3):243-7.
1989: A Kuriu; S Sonoda; Yuzuru Kanakura; K Jozaki; Atsushi Yamatodani; Y Kitamura
Proliferative potential of degranulated murine peritoneal mast cells.
Blood 1989;74(3):925-9.
1989: J Fujita; H Onoue; Y Ebi; H Nakayama; Yuzuru Kanakura
In vitro duplication and in vivo cure of mast-cell deficiency of Sl/Sld mutant mice by cloned 3T3 fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2888-91.
1989: A Kuriu; J Fujita; Yuzuru Kanakura; T Yonezawa; K Yoshida; Y Kitamura
Acceleration of a murine T-cell leukemia associated with loss of interleukin-3 producing activity.
Leukemia research 1989;13(1):77-82.
1988: Toru Nakano; N Waki; Yuzuru Kanakura; J Fujita; S Sonoda; H Asai; Y Kitamura
Hybrid resistance to parental bone marrow-derived cultured mast cells in the skin but not in the peritoneal cavity of (WB X C57BL/6)F1-W/Wv mice.
Experimental hematology 1988;16(11):908-11.
1988: Yuzuru Kanakura; H Thompson; Toru Nakano; T Yamamura; H Asai; Y Kitamura; D D Metcalfe; S J Galli
Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells.
Blood 1988;72(3):877-85.
1988: J Fujita; H Nakayama; H Onoue; Y Ebi; Yuzuru Kanakura; A Kuriu; Y Kitamura
Failure of W/Wv mouse-derived cultured mast cells to enter S phase upon contact with NIH/3T3 fibroblasts.
Blood 1988;72(2):463-8.
1988: N Tominaga; S Katagiri; Y Hamaguchi; Tetsuo Nishiura; Yuzuru Kanakura; Y Kanayama; K Nagao; Y Kakiuchi; K Nishida; T Abe
Plasma cell leukaemia of non-producer type with missing light chain gene rearrangement.
British journal of haematology 1988;69(2):213-8.
1988: Yuzuru Kanakura; A Kuriu; N Waki; Toru Nakano; H Asai; T Yonezawa; Y Kitamura
Changes in numbers and types of mast cell colony-forming cells in the peritoneal cavity of mice after injection of distilled water: evidence that mast cells suppress differentiation of bone marrow-derived precursors.
Blood 1988;71(3):573-80.
1988: J Fujita; H Nakayama; H Onoue; Yuzuru Kanakura; Toru Nakano; H Asai; S Takeda; T Honjo; Y Kitamura
Fibroblast-dependent growth of mouse mast cells in vitro: duplication of mast cell depletion in mutant mice of W/Wv genotype.
Journal of cellular physiology 1988;134(1):78-84.
1988: Y Kitamura; Yuzuru Kanakura; A Kuriu; J Fujita; Toru Nakano
Unique features in differentiation of mast cells.
IARC scientific publications 1988;(92):11-9.
1987: Yuzuru Kanakura; S Sonoda; Toru Nakano; J Fujita; A Kuriu; H Asai; Y Kitamura
Formation of mast-cell colonies in methylcellulose by mouse skin cells and development of mucosal-like mast cells from the cloned cells in the gastric mucosa of W/Wv mice.
The American journal of pathology 1987;129(1):168-76.
1987: Yoshiaki Tomiyama; Yoshiyuki Kurata; H Mizutani; Yuzuru Kanakura; T Tsubakio; T Yonezawa; S Tarui
Platelet glycoprotein IIb as a target antigen in two patients with chronic idiopathic thrombocytopenic purpura.
British journal of haematology 1987;66(4):535-8.