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Hiroshi Kanazawa

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TOP 3
Takahiro Yoshikawa; Hiroshi Kanazawa
Cellular signaling crosstalk between multiple receptors for investigation of pathophysiology in multifactorial diseases--what is clinically-relevant crosstalk?
Gakuya Tamagaki; Hiroshi Kanazawa; Kazuto Hirata
Association of airway pentosidine levels with bronchodilator response mediated by salbutamol administration in asthmatic patients.
Takahiro Yoshikawa; Hiroshi Kanazawa
Integrated effect of EGFR and PAR-1 signaling crosstalk on airway hyperresponsiveness.

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All Publications

2013: Takahiro Yoshikawa; Hiroshi Kanazawa
Cellular signaling crosstalk between multiple receptors for investigation of pathophysiology in multifactorial diseases--what is clinically-relevant crosstalk?
Current medicinal chemistry 2013;20(9):1091-102.
2012: Gakuya Tamagaki; Hiroshi Kanazawa; Kazuto Hirata
Association of airway pentosidine levels with bronchodilator response mediated by salbutamol administration in asthmatic patients.
Pulmonary pharmacology & therapeutics 2012;25(6):478-82.
2012: Takahiro Yoshikawa; Hiroshi Kanazawa
Integrated effect of EGFR and PAR-1 signaling crosstalk on airway hyperresponsiveness.
International journal of molecular medicine 2012;30(1):41-8.
2012: Hiroshi Kanazawa; Yoshihiro Tochino; Tetsuya Watanabe; Kazuhisa Asai; Yukikazu Ichimaru; Kazuto Hirata
Validity of HMGB1 measurement in epithelial lining fluid in patients with COPD.
European journal of clinical investigation 2012;42(4):419-26.
2012: Takahiro Yoshikawa; Hiroshi Kanazawa
Characteristics of young atopic adults with self-reported past wheeze and airway hyperresponsiveness.
Allergology international : official journal of the Japanese Society of Allergology 2012;61(1):65-73.
2012: Takahiro Yoshikawa; Hiroshi Kanazawa
Association of plasma adiponectin levels with cellular hydration state measured using bioelectrical impedance analysis in patients with COPD.
International journal of chronic obstructive pulmonary disease 2012;7():515-21.
2011: Nahoko Shiratsuchi; Yoshihiro Tochino; Kazuhisa Asai; Hiroshi Kanazawa; Toyoki Kodama; Shigenori Kyoh; Kazuto Hirata
Measurement of soluble perforin, a marker of CD8+ T lymphocyte activation in epithelial lining fluid.
Respiratory medicine 2011;105(12):1885-90.
2011: Hiroshi Kanazawa; Kazuto Hirata
[The cutting-edge of medicine; cross-talk between airway and vascular remodeling].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(11):3361-7.
2011: Daiki Kobayashi; Shigenori Kyoh; Yoshihiro Tochino; Kazuhisa Asai; Yukikazu Ichimaru; Hiroshi Kanazawa; Kazuto Hirata
Comparison of alveolar nitric oxide concentrations using two different methods for assessing small airways obstruction in asthma.
Respirology (Carlton, Vic.) 2011;16(5):862-8.
2011: Hiroki Fujimoto; Hiroshi Kanazawa; Tetsuya Watanabe; Kazuhisa Asai; Kazuto Hirata
Association of six-minute walk distance (6MWD) with resting pulmonary function in patients with chronic obstructive pulmonary disease (COPD).
Osaka city medical journal 2011;57(1):21-9.
2011: Hiroshi Kanazawa; Yoshihiro Tochino; Shigenori Kyoh; Yukikazu Ichimaru; Kazuhisa Asai; Kazuto Hirata
Potential roles of pentosidine in age-related and disease-related impairment of pulmonary functions in patients with asthma.
The Journal of allergy and clinical immunology 2011;127(4):899-904.
2011: Tetsuya Watanabe; Kazuhisa Asai; Hiroki Fujimoto; Hidenori Tanaka; Hiroshi Kanazawa; Kazuto Hirata
Increased levels of HMGB-1 and endogenous secretory RAGE in induced sputum from asthmatic patients.
Respiratory medicine 2011;105(4):519-25.
2011: Takahiro Yoshikawa; Hiroshi Kanazawa
Phenotypic differences between asymptomatic airway hyperresponsiveness and remission of asthma.
Respiratory medicine 2011;105(1):24-30.
2010: Hiroshi Kanazawa; Toyoki Kodama; Kazuhisa Asai; Saeko Matsumura; Kazuto Hirata
Increased levels of N(epsilon)-(carboxymethyl)lysine in epithelial lining fluid from peripheral airways in patients with chronic obstructive pulmonary disease: a pilot study.
Clinical science (London, England : 1979) 2010;119(3):143-9.
2010: Hiroshi Kanazawa; Shigenori Kyoh; Kazuhisa Asai; Kazuto Hirata
Validity of measurement of two specific biomarkers for the assessment of small airways inflammation in asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 2010;47(4):400-6.
2010: Takahiro Yoshikawa; Hiroshi Kanazawa; Junji Tanaka; Shigeo Fujimoto; Takushi Yamamoto
Gene polymorphism of epidermal growth factor receptor and airway hyperresponsiveness in young allergic subjects without respiratory symptoms.
Medical science monitor : international medical journal of experimental and clinical research 2010;16(4):CR163-171.
2009: Hiroshi Kanazawa; Kazuhisa Asai; Yoshihiro Tochino; S Kyoh; T Kodama; Kazuto Hirata
Increased levels of angiopoietin-2 in induced sputum from smoking asthmatic patients.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(9):1330-7.
2009: Hiroshi Kanazawa; Shigenori Kyoh; Yoshihiro Tochino; Toyoki Kodama; Kazuhisa Asai; Kazuto Hirata
[Potential mechanisms of airway remodeling initiated by activated thrombin in asthma].
Arerugī = [Allergy] 2009;58(5):554-9.
2009: Toyoki Kodama; Hiroshi Kanazawa; Yoshihiro Tochino; Shigenori Kyoh; Kazuhisa Asai; Kazuto Hirata
A technological advance comparing epithelial lining fluid from different regions of the lung in smokers.
Respiratory medicine 2009;103(1):35-40.
2008: Shigenori Kyoh; Hiroshi Kanazawa; Yoshihiro Tochino; Toyoki Kodama; Kazuhisa Asai; Kazuto Hirata
Comparison of N-epsilon-(Carboxymethyl)Lysine levels and percentage of eosinophils in induced sputum for assessment of small airway involvements in asthma.
Medical science monitor : international medical journal of experimental and clinical research 2008;14(7):CR375-8.
2008: Y Ichimaru; Hiroshi Kanazawa; H Kamoi; S Kyoh; Yoshihiro Tochino; T Kodama; K Hirata
Correlations of health-related quality of life questionnaire results in asthma and allergic rhinitis: effects of a leukotriene receptor antagonist.
The Journal of international medical research 2008;36(3):559-66.
2008: Hiroshi Kanazawa; Yoshihiro Tochino; Kazuhisa Asai
Angiopoietin-2 as a contributing factor of exercise-induced bronchoconstriction in asthmatic patients receiving inhaled corticosteroid therapy.
The Journal of allergy and clinical immunology 2008;121(2):390-5.
2007: Yoshihiro Tochino; Hiroshi Kanazawa; Yukikazu Ichimaru; Kazuhisa Asai; Shigenori Kyoh; Kazuto Hirata
Nepsilon-(carboxymethyl)lysine, a major advanced glycation end product in exhaled breath condensate as a biomarker of small airway involvement in asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 2007;44(10):861-6.
2007: Hiroshi Kanazawa
Role of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease.
Medical science monitor : international medical journal of experimental and clinical research 2007;13(11):RA189-195.
2007: Hiroshi Kanazawa; Takahiro Yoshikawa
Up-regulation of thrombin activity induced by vascular endothelial growth factor in asthmatic airways.
Chest 2007;132(4):1169-74.
2007: Hiroshi Kanazawa; Kazuhisa Asai; Saeko Nomura
Changes in circulating thrombomodulin levels with exercise in patients with chronic obstructive pulmonary disease.
Respirology (Carlton, Vic.) 2007;12(5):670-4.
2007: Hiroshi Kanazawa
Microvascular theory of exercise-induced bronchoconstriction in asthma: potential implication of vascular endothelial growth factor.
Inflammation & allergy drug targets 2007;6(2):133-7.
2007: Hiroshi Kanazawa; Saeko Nomura; Kazuhisa Asai
Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients.
Chest 2007;131(4):1035-41.
2007: Hiroshi Kanazawa; Kazuhisa Asai; Saeko Nomura
Vascular endothelial growth factor as a non-invasive marker of pulmonary vascular remodeling in patients with bronchitis-type of COPD.
Respiratory research 2007;8():22.
2007: Hiroshi Kanazawa
Efficacy of azithromycin administration in prevention of respiratory tract infection after bronchoscopic biopsy: a randomized, controlled trial.
Respirology (Carlton, Vic.) 2007;12(1):70-5.
2006: Hiroshi Kanazawa
Relationship between hepatitis C virus infection and pulmonary disorders: potential mechanisms of interaction.
Expert review of clinical immunology 2006;2(5):801-10.
2006: Hiroshi Kanazawa; Yoshihiro Tochino; Yukitoshi Ichimaru; Toyoki Kodama; Shigenori Kyoh; Nobuaki Umeda
Role of vascular endothelial growth factor in pulmonary endothelial cell injury by exercise challenge in asthmatic patients.
The Journal of asthma : official journal of the Association for the Care of Asthma 2006;43(4):267-71.
2006: Saeko Nomura; Hiroshi Kanazawa; Kazuhisa Asai; Naho Nomura; Kazuto Hirata; Junichi Yoshikawa
Potential mechanisms of improvement of airway hyperresponsiveness by inhaled corticosteroid therapy in asthmatic patients.
The Journal of asthma : official journal of the Association for the Care of Asthma 2006;43(2):113-7.
2006: Hiroshi Kanazawa
Anticholinergic agents in asthma: chronic bronchodilator therapy, relief of acute severe asthma, reduction of chronic viral inflammation and prevention of airway remodeling.
Current opinion in pulmonary medicine 2006;12(1):60-7.
2006: Hiroshi Kanazawa; Junichi Yoshikawa
Alterations in T-lymphocyte subsets in the airways of asthmatic patients with active hepatitis C virus infection.
Respiration; international review of thoracic diseases 2006;73(3):318-23.
2005: Hiroshi Kanazawa; Junichi Yoshikawa
Effect of beclomethasone dipropionate on basic fibroblast growth factor levels in induced sputum samples from asthmatic patients.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;95(6):546-50.
2005: Hiroshi Kanazawa; Junichi Yoshikawa
Elevated oxidative stress and reciprocal reduction of vascular endothelial growth factor levels with severity of COPD.
Chest 2005;128(5):3191-7.
2005: Hiroshi Kanazawa; Junichi Yoshikawa
A case-control study of bronchial asthma associated with ulcerative colitis: role of airway microvascular permeability.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(11):1432-6.
2005: Hiroshi Kanazawa; Yohsuke Eguchi; Naho Nomura; Junichi Yoshikawa
Analysis of vascular endothelial growth factor levels in induced sputum samples from patients with cough variant asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2005;95(3):266-71.
2005: Saeko Nomura; Hiroshi Kanazawa; Kazuto Hirata; Hiroshi Iwao; Junichi Yoshikawa
Relationship between vascular endothelial growth factor and angiopoietin-2 in asthmatics before and after inhaled beclomethasone therapy.
The Journal of asthma : official journal of the Association for the Care of Asthma 2005;42(2):141-6.
2005: Shigeki Mitsuoka; Hiroshi Kanazawa
Images in Thorax. An unique case of primary pulmonary cryptococcosis with extensive chest wall invasion.
Thorax 2005;60(1):86.
2004: Hiroshi Kanazawa; Yoshitaka Tateishi; Junichi Yoshikawa
Acute effects of nifedipine administration in pulmonary haemodynamics and oxygen delivery during exercise in patients with chronic obstructive pulmonary disease: implication of the angiotensin-converting enzyme gene polymorphisms.
Clinical physiology and functional imaging 2004;24(4):224-8.
2004: Hiroshi Kanazawa; Junichi Yoshikawa
Accelerated decline in lung function and impaired reversibility with salbutamol in asthmatic patients with chronic hepatitis C virus infection: a 6-year follow-up study.
The American journal of medicine 2004;116(11):749-52.
2004: Hiroshi Kanazawa; Saeko Nomura; Junichi Yoshikawa
Role of microvascular permeability on physiologic differences in asthma and eosinophilic bronchitis.
American journal of respiratory and critical care medicine 2004;169(10):1125-30.
2004: Hiroshi Kanazawa; Takahiro Yoshikawa; Kazuto Hirata; Junichi Yoshikawa
Effects of pranlukast administration on vascular endothelial growth factor levels in asthmatic patients.
Chest 2004;125(5):1700-5.
2004: Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Increased responses to inhaled oxitropium bromide in asthmatic patients with active hepatitis C virus infection.
Chest 2004;125(4):1368-71.
2004: Kenichiro Otani; Hiroshi Kanazawa; Hiroshi Fujiwara; Kazuto Hirata; Shigeo Fujimoto; Junichi Yoshikawa
Determinants of the severity of exercise-induced bronchoconstriction in patients with asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 2004;41(3):271-8.
2003: Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Influence of oxygen administration on pulmonary haemodynamics and tissue oxygenation during exercise in COPD patients with different ACE genotypes.
Clinical physiology and functional imaging 2003;23(6):332-6.
2003: Hiroshi Kanazawa; Saeko Nomura; Kazuto Hirata; Junichi Yoshikawa
Effect of inhaled beclomethasone dipropionate on peroxynitrite inhibitory activity in induced sputum from asthmatic patients.
Chest 2003;124(5):1755-61.
2003: Takashi Okamoto; Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Evaluation of oxygen uptake kinetics and oxygen kinetics of peripheral skeletal muscle during recovery from exercise in patients with chronic obstructive pulmonary disease.
Clinical physiology and functional imaging 2003;23(5):257-62.
2003: Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Effects of captopril administration on pulmonary haemodynamics and tissue oxygenation during exercise in ACE gene subtypes in patients with COPD: a preliminary study.
Thorax 2003;58(7):629-31.
2003: Kazuhisa Asai; Hiroshi Kanazawa; H Kamoi; S Shiraishi; Kazuto Hirata; Junichi Yoshikawa
Increased levels of vascular endothelial growth factor in induced sputum in asthmatic patients.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(5):595-9.
2003: Hiroshi Kanazawa; Kazuhisa Asai; Kazuto Hirata; Junichi Yoshikawa
Possible effects of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease.
The American journal of medicine 2003;114(5):354-8.
2003: Hiroshi Kanazawa; Takashi Mamoto; Kazuto Hirata; Junichi Yoshikawa
Interferon therapy induces the improvement of lung function by inhaled corticosteroid therapy in asthmatic patients with chronic hepatitis C virus infection: a preliminary study.
Chest 2003;123(2):600-3.
2003: Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Accelerated decline of lung function in COPD patients with chronic hepatitis C virus infection: a preliminary study based on small numbers of patients.
Chest 2003;123(2):596-9.
2003: Hiroshi Kanazawa; S Shiraishi; Kazuto Hirata; Junichi Yoshikawa
Imbalance between levels of nitrogen oxides and peroxynitrite inhibitory activity in chronic obstructive pulmonary disease.
Thorax 2003;58(2):106-9.
2002: Kazuhisa Asai; Hiroshi Kanazawa; Kenichiro Otani; Satoshi Shiraishi; Kazuto Hirata; Junichi Yoshikawa
Imbalance between vascular endothelial growth factor and endostatin levels in induced sputum from asthmatic subjects.
The Journal of allergy and clinical immunology 2002;110(4):571-5.
2002: Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Involvement of vascular endothelial growth factor in exercise induced bronchoconstriction in asthmatic patients.
Thorax 2002;57(10):885-8.
2002: Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Transient increase in endothelin-1 levels in the pulmonary circulation during exercise while breathing of oxygen in patients with chronic obstructive pulmonary disease.
Internal medicine (Tokyo, Japan) 2002;41(7):522-5.
2002: Hiroshi Kanazawa; S Shiraishi; Kazuto Hirata; Junichi Yoshikawa
Decreased peroxynitrite inhibitory activity in induced sputum in patients with bronchial asthma.
Thorax 2002;57(6):509-12.
2002: Hiroshi Kanazawa; Toshihiro Otsuka; Kazuto Hirata; Junichi Yoshikawa
Association between the angiotensin-converting enzyme gene polymorphisms and tissue oxygenation during exercise in patients with COPD.
Chest 2002;121(3):697-701.
2002: Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Nitrogen oxides reduce albuterol-induced bronchodilation in patients with bronchial asthma.
Respiration; international review of thoracic diseases 2002;69(6):490-5.
2000: Hiroshi Kanazawa; Kazuto Hirata; Junichi Yoshikawa
Role of endogenous nitric oxide in exercise-induced airway narrowing in patients with bronchial asthma.
The Journal of allergy and clinical immunology 2000;106(6):1081-7.