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Yasufumi Kaneda

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Gerardo Rodriguez-Araujo; Tetsuya Shiuchi; Yoichi Takami; Hiroki Hayashi; Issei Komuro; Yasuhiko Minokoshi; Masaki Mori; Ryuichi Morishita; Hironori Nakagami; Yoshikazu Nakaoka; Yasufumi Kaneda
Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway.
Kotaro Saga; Katsuto Tamai; Takehiko Yamazaki; Yasufumi Kaneda
Systemic administration of a novel immune-stimulatory pseudovirion suppresses lung metastatic melanoma by regionally enhancing IFN-γ production.
Motonari Nomura; Takashi Shimbo; Masahiro Fukuzawa; Yasuhide Miyamoto; Yasufumi Kaneda
13-Cis retinoic acid can enhance the antitumor activity of non-replicating Sendai virus particle against neuroblastoma.

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2013: Gerardo Rodriguez-Araujo; Tetsuya Shiuchi; Yoichi Takami; Hiroki Hayashi; Issei Komuro; Yasuhiko Minokoshi; Masaki Mori; Ryuichi Morishita; Hironori Nakagami; Yoshikazu Nakaoka; Yasufumi Kaneda
Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway.
Cellular and molecular life sciences : CMLS 2013;70(6):1123-33.
2013: Kotaro Saga; Katsuto Tamai; Takehiko Yamazaki; Yasufumi Kaneda
Systemic administration of a novel immune-stimulatory pseudovirion suppresses lung metastatic melanoma by regionally enhancing IFN-γ production.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(3):668-79.
2013: Motonari Nomura; Takashi Shimbo; Masahiro Fukuzawa; Yasuhide Miyamoto; Yasufumi Kaneda
13-Cis retinoic acid can enhance the antitumor activity of non-replicating Sendai virus particle against neuroblastoma.
Cancer science 2013;104(2):238-44.
2013: Makiko Takeichi; Masaki Mori; Hironori Nakagami; Keisuke Nimura; Yasufumi Kaneda
The transcription factors Tbx18 and Wt1 control the epicardial epithelial-mesenchymal transition through bi-directional regulation of Slug in murine primary epicardial cells.
PloS one 2013;8(2):e57829.
2012: Taeko Matsushima-Miyagi; Tomoyuki Nishikawa; Motonari Nomura; Kotaro Saga; Takashi Shimbo; Koji Hatano; Liu Li-Wen; Yasufumi Kaneda
TRAIL and Noxa are selectively upregulated in prostate cancer cells downstream of the RIG-I/MAVS signaling pathway by nonreplicating Sendai virus particles.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(22):6271-83.
2012: Hirofumi Makino; Toshio Ogihara; Yoshiki Sawa; Keita Yamasaki; Motokuni Aoki; Junya Azuma; Naotaka Hashiya; Yasufumi Kaneda; Ryuichi Morishita
Long-term follow-up evaluation of results from clinical trial using hepatocyte growth factor gene to treat severe peripheral arterial disease.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(10):2503-9.
2012: Makoto Sakai; Naohiro Fujimoto; K Ishii; Yasufumi Kaneda; Hiroyuki Nakamura; Kunio Awazu
In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope.
Journal of biomedical optics 2012;17(7):77009.
2012: Makoto Sakai; Naohiro Fujimoto; K Ishii; Yasufumi Kaneda; Hiroyuki Nakamura; Kunio Awazu
In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope.
Journal of biomedical optics 2012;17(7):077009.
2012: Makoto Sakai; Naohiro Fujimoto; K Ishii; Yasufumi Kaneda; Hiroyuki Nakamura; Kunio Awazu
In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope.
Journal of biomedical optics 2012;17(7):078002.
2012: E Kiyohara; K Tamai; I Katayama; Yasufumi Kaneda
The combination of chemotherapy with HVJ-E containing Rad51 siRNA elicited diverse anti-tumor effects and synergistically suppressed melanoma.
Gene therapy 2012;19(7):734-41.
2012: Hironori Nakagami; Tomoyuki Nishikawa; Takashi Shimosato; Katsuto Tamai; Nao Tamura; Kazunori Tomono; Akito Maeda; Masayoshi Mochizuki; Ryuichi Morishita; Toshinori Moriya; Hajime Hibino; Yasufumi Kaneda
Modification of a novel angiogenic peptide, AG30, for the development of novel therapeutic agents.
Journal of cellular and molecular medicine 2012;16(7):1629-39.
2012: Hiroki Hayashi; Rodriguez Gerardo Araujo; Nobutaka Koibuchi; Hiroshi Koriyama; Akito Maeda; Masaki Mori; Ryuichi Morishita; Hironori Nakagami; Eiji Oiki; Naoyuki Sato; Munehisa Shimamura; Makiko Takeichi; Katsuto Tamai; Yasufumi Kaneda
HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(6):2306-17.
2012: Masaki Mori; Hironori Nakagami; Keisuke Nimura; Gerardo Rodriguez-Araujo; Yasufumi Kaneda
Essential role for miR-196a in brown adipogenesis of white fat progenitor cells.
PLoS biology 2012;10(4):e1001314.
2012: Koji Hatano; Yasuhide Miyamoto; Masaki Mori; Yasutomo Nakai; Keisuke Nimura; Norio Nonomura; Yasufumi Kaneda
Androgen-regulated transcriptional control of sialyltransferases in prostate cancer cells.
PloS one 2012;7(2):e31234.
2011: Koji Hatano; Yasuhide Miyamoto; Norio Nonomura; Yasufumi Kaneda
Expression of gangliosides, GD1a, and sialyl paragloboside is regulated by NF-κB-dependent transcriptional control of α2,3-sialyltransferase I, II, and VI in human castration-resistant prostate cancer cells.
International journal of cancer. Journal international du cancer 2011;129(8):1838-47.
2011: Hiroshi Fujita; Katsuto Tamai; Masako Kawachi; Kotaro Saga; Takashi Shimbo; Takehiko Yamazaki; Yasufumi Kaneda
Methyl-beta cyclodextrin alters the production and infectivity of Sendai virus.
Archives of virology 2011;156(6):995-1005.
2011: Masahide Matsuda; Keisuke Nimura; Takashi Shimbo; Toshimitsu Hamasaki; Tetsuya Yamamoto; Akira Matsumura; Yasufumi Kaneda
Immunogene therapy using immunomodulating HVJ-E vector augments anti-tumor effects in murine malignant glioma.
Journal of neuro-oncology 2011;103(1):19-31.
2011: Katsuto Tamai; Takehiko Yamazaki; Takenao Chino; Masaru Ishii; Satoru Otsuru; Yasushi Kikuchi; Shin Iinuma; Kotaro Saga; Keisuke Nimura; Takashi Shimbo; Noriko Umegaki; Ichiro Katayama; Jun-Ichi Miyazaki; Junji Takeda; John A McGrath; Jouni Uitto; Yasufumi Kaneda
PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(16):6609-14.
2011: Ryuichi Morishita; Hirofumi Makino; Motokuni Aoki; Naotaka Hashiya; Keita Yamasaki; Junya Azuma; Yoshiaki Taniyama; Yoshiki Sawa; Yasufumi Kaneda; Toshio Ogihara
Phase I/IIa clinical trial of therapeutic angiogenesis using hepatocyte growth factor gene transfer to treat critical limb ischemia.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(3):713-20.
2011: Katsunobu Kashiwagi; Keisuke Nimura; Kiyoe Ura; Yasufumi Kaneda
DNA methyltransferase 3b preferentially associates with condensed chromatin.
Nucleic acids research 2011;39(3):874-88.
2011: Hitoshi Fujii; Akifumi Matsuyama; Hiroshi Komoda; Masao Sasai; Minoru Suzuki; Tomoyuki Asano; Yuichiro Doki; Mitsunori Kirihata; Koji Ono; Yasuhiko Tabata; Yasufumi Kaneda; Yoshiki Sawa; Chun Man Lee
Cationized gelatin-HVJ envelope with sodium borocaptate improved the BNCT efficacy for liver tumors in vivo.
Radiation oncology (London, England) 2011;6():8.
2010: Yasufumi Kaneda
A non-replicating oncolytic vector as a novel therapeutic tool against cancer.
BMB reports 2010;43(12):773-80.
2010: Keisuke Nimura; Kiyoe Ura; Yasufumi Kaneda
Histone methyltransferases: regulation of transcription and contribution to human disease.
Journal of molecular medicine (Berlin, Germany) 2010;88(12):1213-20.
2010: Hiroshi Koriyama; Hironori Nakagami; Tomohiro Katsuya; Ken Sugimoto; Hidetoshi Yamashita; Yoichi Takami; Shiro Maeda; Michiaki Kubo; Atsushi Takahashi; Yusuke Nakamura; Toshio Ogihara; Hiromi Rakugi; Yasufumi Kaneda; Ryuichi Morishita
Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
Journal of atherosclerosis and thrombosis 2010;17(10):1054-62.
2010: Yasufumi Kaneda
Update on non-viral delivery methods for cancer therapy: possibilities of a drug delivery system with anticancer activities beyond delivery as a new therapeutic tool.
Expert opinion on drug delivery 2010;7(9):1079-93.
2010: Yasufumi Kaneda
[Current status of gene therapy in Japan and other countries].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 8():577-83.
2010: Hiroshi Koriyama; Hironori Nakagami; Tomohiro Katsuya; Hiroshi Akasaka; Shigeyuki Saitoh; Kazuaki Shimamoto; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita; Hiromi Rakugi
Variation in OSBPL10 is associated with dyslipidemia.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(5):511-4.
2010: Masahiko Tanaka; Takashi Shimbo; Yasushi Kikuchi; Masahide Matsuda; Yasufumi Kaneda
Sterile alpha motif containing domain 9 is involved in death signaling of malignant glioma treated with inactivated Sendai virus particle (HVJ-E) or type I interferon.
International journal of cancer. Journal international du cancer 2010;126(8):1982-91.
2010: Takashi Shimbo; Atsushi Tanemura; Takehiko Yamazaki; Katsuto Tamai; Ichiro Katayama; Yasufumi Kaneda
Serum anti-BPAG1 auto-antibody is a novel marker for human melanoma.
PloS one 2010;5(5):e10566.
2009: M Matsuda; Toshiya Yamamoto; Akihide Matsumura; Yasufumi Kaneda
Highly efficient eradication of intracranial glioblastoma using Eg5 siRNA combined with HVJ envelope.
Gene therapy 2009;16(12):1465-76.
2009: Keisuke Nimura; Kiyoe Ura; Hidetaka Shiratori; Masahito Ikawa; Masaru Okabe; Robert J Schwartz; Yasufumi Kaneda
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
Nature 2009;460(7252):287-91.
2009: Katsuto Tamai; Yasufumi Kaneda; Jouni Uitto
Molecular therapies for heritable blistering diseases.
Trends in molecular medicine 2009;15(7):285-92.
2009: Masaki Mori; Hironori Nakagami; Nobutaka Koibuchi; Koichi Miura; Yoichi Takami; Hiroshi Koriyama; Hiroki Hayashi; Hisataka Sabe; Naoki Mochizuki; Ryuichi Morishita; Yasufumi Kaneda
Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis.
Molecular biology of the cell 2009;20(13):3115-24.
2009: Yasufumi Kaneda
[Progress of human gene therapy].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(6):1180-4.
2009: Hiroki Hayashi; Hironori Nakagami; Yoichi Takami; Hiroshi Koriyama; Masaki Mori; Katsuto Tamai; Jianxin Sun; Kaori Nagao; Ryuichi Morishita; Yasufumi Kaneda
FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):909-14.
2009: Yoshifumi Kawaguchi; Yasuhide Miyamoto; Takehiro Inoue; Yasufumi Kaneda
Efficient eradication of hormone-resistant human prostate cancers by inactivated Sendai virus particle.
International journal of cancer. Journal international du cancer 2009;124(10):2478-87.
2009: Tomoyuki Nishikawa; Hironori Nakagami; Akito Maeda; Ryuichi Morishita; Nobuhiko Miyazaki; Toshihiro Ogawa; Yasuhiko Tabata; Yasushi Kikuchi; Hiroki Hayashi; Yoshiro Tatsu; Noboru Yumoto; Katsuto Tamai; Kazunori Tomono; Yasufumi Kaneda
Development of a novel antimicrobial peptide, AG-30, with angiogenic properties.
Journal of cellular and molecular medicine 2009;13(3):535-46.
2008: Takenao Chino; Katsuto Tamai; Takehiko Yamazaki; Satoru Otsuru; Yasushi Kikuchi; Keisuke Nimura; Masayuki Endo; Miki Nagai; Jouni Uitto; Yasuo Kitajima; Yasufumi Kaneda
Bone marrow cell transfer into fetal circulation can ameliorate genetic skin diseases by providing fibroblasts to the skin and inducing immune tolerance.
The American journal of pathology 2008;173(3):803-14.
2008: Yasushi Kikuchi; Katsuto Tamai; Yasufumi Kaneda
Cutaneous gene delivery.
Journal of dermatological science 2008;50(2):87-98.
2008: Hayato Suzuki; Masayuki Kurooka; Yoko Hiroaki; Yoshinori Fujiyoshi; Yasufumi Kaneda
Sendai virus F glycoprotein induces IL-6 production in dendritic cells in a fusion-independent manner.
FEBS letters 2008;582(9):1325-9.
2008: Yukihiro Saito; Hironori Nakagami; Masayuki Kurooka; Yoichi Takami; Yasushi Kikuchi; H Hayashi; Tomoyuki Nishikawa; Katsuto Tamai; Ryuichi Morishita; N Azuma; T Sasajima; Yasufumi Kaneda
Cold shock domain protein A represses angiogenesis and lymphangiogenesis via inhibition of serum response element.
Oncogene 2008;27(13):1821-33.
2008: Yasufumi Kaneda
Applications of Hemagglutinating Virus of Japan in therapeutic delivery systems.
Expert opinion on drug delivery 2008;5(2):221-33.
2008: Kotaro Saga; Katsuto Tamai; Masako Kawachi; Takashi Shimbo; Hiroshi Fujita; Takehiko Yamazaki; Yasufumi Kaneda
Functional modification of Sendai virus by siRNA.
Journal of biotechnology 2008;133(3):386-94.
2008: Satoru Otsuru; Katsuto Tamai; Takehiko Yamazaki; Hideki Yoshikawa; Yasufumi Kaneda
Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway.
Stem cells (Dayton, Ohio) 2008;26(1):223-34.
2008: Atsuko Fujihara; Masayuki Kurooka; Tsuneharu Miki; Yasufumi Kaneda
Intratumoral injection of inactivated Sendai virus particles elicits strong antitumor activity by enhancing local CXCL10 expression and systemic NK cell activation.
Cancer immunology, immunotherapy : CII 2008;57(1):73-84.
2007: Takashi Shimbo; Masako Kawachi; Kotaro Saga; Hiroshi Fujita; Takehiko Yamazaki; Katsuto Tamai; Yasufumi Kaneda
Development of a transferrin receptor-targeting HVJ-E vector.
Biochemical and biophysical research communications 2007;364(3):423-8.
2007: Hironori Nakagami; Yasushi Kikuchi; Tomohiro Katsuya; Ryuichi Morishita; Hiroshi Akasaka; Shigeyuki Saitoh; Hiromi Rakugi; Yasufumi Kaneda; Kazuaki Shimamoto; Toshio Ogihara
Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(12):1239-46.
2007: Takashi Miyake; Motokuni Aoki; Hisao Masaki; Tomio Kawasaki; Masako Oishi; Kazusaburo Kataoka; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Regression of abdominal aortic aneurysms by simultaneous inhibition of nuclear factor kappaB and ets in a rabbit model.
Circulation research 2007;101(11):1175-84.
2007: Hiroki Hayashi; Hironori Nakagami; Yoichi Takami; Naoyuki Sato; Yukihiro Saito; Tomoyuki Nishikawa; Masaki Mori; Hiroshi Koriyama; Katsuto Tamai; Ryuichi Morishita; Yasufumi Kaneda
Involvement of gamma-secretase in postnatal angiogenesis.
Biochemical and biophysical research communications 2007;363(3):584-90.
2007: Masako Kawachi; Katsuto Tamai; Kotaro Saga; Takehiko Yamazaki; Hiroshi Fujita; Takashi Shimbo; Yasushi Kikuchi; Keisuke Nimura; Koji Nishifuji; Masayuki Amagai; Jouni Uitto; Yasufumi Kaneda
Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin.
Human gene therapy 2007;18(10):881-94.
2007: Yoichi Takami; Hironori Nakagami; Ryuichi Morishita; Tomohiro Katsuya; Tai-Xing Cui; Tomonaga Ichikawa; Yukihiro Saito; Hiroki Hayashi; Yasushi Kikuchi; Tomoyuki Nishikawa; Yoshichika Baba; Osamu Yasuda; Hiromi Rakugi; Toshio Ogihara; Yasufumi Kaneda
Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(10):2184-90.
2007: Masanori Hayashi; Keisuke Nimura; Katsunobu Kashiwagi; Taku Harada; Kunio Takaoka; Hiroyuki Kato; Katsuto Tamai; Yasufumi Kaneda
Comparative roles of Twist-1 and Id1 in transcriptional regulation by BMP signaling.
Journal of cell science 2007;120(Pt 8):1350-7.
2007: Satoru Otsuru; Katsuto Tamai; Takehiko Yamazaki; Hideki Yoshikawa; Yasufumi Kaneda
Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice.
Biochemical and biophysical research communications 2007;354(2):453-8.
2007: Eri Yasuoka; Kazuo Oshima; Katsuto Tamai; Takeshi Kubo; Yasufumi Kaneda
Needleless intranasal administration of HVJ-E containing allergen attenuates experimental allergic rhinitis.
Journal of molecular medicine (Berlin, Germany) 2007;85(3):283-92.
2007: Hirokazu Kawano; Shintarou Komaba; Toshihide Kanamori; Yasufumi Kaneda
A new therapy for highly effective tumor eradication using HVJ-E combined with chemotherapy.
BMC medicine 2007;5():28.
2007: Masayuki Kurooka; Yasufumi Kaneda
Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
Cancer research 2007;67(1):227-36.
2007: Saroj Suvanasuthi; Katsuto Tamai; Yasufumi Kaneda
Rapid transport of plasmid DNA into the nucleolus via actin depolymerization using the HVJ envelope vector.
The journal of gene medicine 2007;9(1):55-62.
2006: Hiromi Koike; A Ishida; Munehisa Shimamura; Shinya Mizuno; Tadashi Nakamura; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Prevention of onset of Parkinson's disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson's disease.
Gene therapy 2006;13(23):1639-44.
2006: Keisuke Nimura; Chisaki Ishida; Hiroshi Koriyama; Kenichiro Hata; Shinya Yamanaka; En Li; Kiyoe Ura; Yasufumi Kaneda
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(10):1225-37.
2006: Suguru Shiraya; Ken Miwa; Motokuni Aoki; Takashi Miyake; Masako Oishi; Kazusaburo Kataoka; Shigetsugu Ohgi; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Hypertension accelerated experimental abdominal aortic aneurysm through upregulation of nuclear factor kappaB and Ets.
Hypertension 2006;48(4):628-36.
2006: Yukihiro Saito; Hironori Nakagami; Ryuichi Morishita; Yoichi Takami; Yasushi Kikuchi; Hiroki Hayashi; Tomoyuki Nishikawa; Katsuto Tamai; Nobuyoshi Azuma; Tadahiro Sasajima; Yasufumi Kaneda
Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis.
Circulation 2006;114(11):1177-84.
2006: Shin-ichi Takeda; Bungo Terazono; Fumihito Mishima; Hironori Nakagami; Shigehiro Nishijima; Yasufumi Kaneda
Novel drug delivery system by surface modified magnetic nanoparticles.
Journal of nanoscience and nanotechnology 2006;6(9-10):3269-76.
2006: Takashi Miyake; Motokuni Aoki; Suguru Shiraya; Kazuo Tanemoto; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model.
Journal of molecular and cellular cardiology 2006;41(3):431-40.
2006: Tetsuya Tomita; Yasuo Kunugiza; Naruya Tomita; Hiroshi Takano; Ryuichi Morishita; Yasufumi Kaneda; Hideki Yoshikawa
E2F decoy oligodeoxynucleotide ameliorates cartilage invasion by infiltrating synovium derived from rheumatoid arthritis.
International journal of molecular medicine 2006;18(2):257-65.
2006: Yasuo Kunugiza; Naruya Tomita; Yoshiaki Taniyama; Tetsuya Tomita; Mariana Kiomy Osako; Katsuto Tamai; Tadashi Tanabe; Yasufumi Kaneda; Hideki Yoshikawa; Ryuichi Morishita
Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet.
Gene therapy 2006;13(15):1143-52.
2006: H Shimizu; Hironori Nakagami; I Tsukamoto; S Morita; Yasuo Kunugiza; Tetsuya Tomita; Hideki Yoshikawa; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita
NFkappaB decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts.
Gene therapy 2006;13(12):933-41.
2006: Shinsuke Koyama; Tadashi Kimura; Kazuhide Ogita; Hitomi Nakamura; Chisa Tabata; Khan Md Abu Hadi Noor Ali; Kumiko Temma-Asano; Koichiro Shimoya; Tateki Tsutsui; Masayasu Koyama; Yasufumi Kaneda; Yuji Murata
Simple and highly efficient method for transient in vivo gene transfer to mid-late pregnant mouse uterus.
Journal of reproductive immunology 2006;70(1-2):59-69.
2006: Nobutaka Koibuchi; Yoshiaki Taniyama; Kaori Nagao; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
The effect of VEGF on blood vessels and blood cells during Xenopus development.
Biochemical and biophysical research communications 2006;344(1):339-45.
2006: Hitomi Nakamura; Tadashi Kimura; Shinsuke Koyama; Kazuhide Ogita; Tateki Tsutsui; Koichiro Shimoya; Takeshi Taniguchi; Masayasu Koyama; Yasufumi Kaneda; Yuji Murata
Mouse model of human infertility: transient and local inhibition of endometrial STAT-3 activation results in implantation failure.
FEBS letters 2006;580(11):2717-22.
2006: Yasufumi Kaneda; Yasuhiko Tabata
Non-viral vectors for cancer therapy.
Cancer science 2006;97(5):348-54.
2006: Hironori Nakagami; Ryuichi Morishita; Kazuhisa Maeda; Yasushi Kikuchi; Toshio Ogihara; Yasufumi Kaneda
Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy.
Journal of atherosclerosis and thrombosis 2006;13(2):77-81.
2006: Hironori Nakagami; Naruya Tomita; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita
Anti-oxidant gene therapy by NF kappa B decoy oligodeoxynucleotide.
Current pharmaceutical biotechnology 2006;7(2):95-100.
2006: Hidetoshi Mima; Seiji Yamamoto; Makoto Ito; Ryuji Tomoshige; Yasuhiko Tabata; Katsuto Tamai; Yasufumi Kaneda
Targeted chemotherapy against intraperitoneally disseminated colon carcinoma using a cationized gelatin-conjugated HVJ envelope vector.
Molecular cancer therapeutics 2006;5(4):1021-8.
2006: Yosuke Seki; Hirofumi Yamamoto; Chew Yee Ngan; Masayoshi Yasui; Naruya Tomita; Kotaro Kitani; Ichiro Takemasa; Masataka Ikeda; Mitsugu Sekimoto; Nariaki Matsuura; Chris Albanese; Yasufumi Kaneda; Richard G Pestell; Morito Monden
Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway.
Molecular cancer therapeutics 2006;5(4):985-94.
2006: Tomoyuki Nishikawa; Hironori Nakagami; Atsushi Matsuki; Akito Maeda; Chiah Yian Yo; Taku Harada; Ryuichi Morishita; Katsuto Tamai; Yasufumi Kaneda
Development of high-throughput functional screening of therapeutic genes, using a hemagglutinating virus of Japan envelope vector.
Human gene therapy 2006;17(4):470-5.
2006: Munehisa Shimamura; Naoyuki Sato; Satoshi Waguri; Yasuo Uchiyama; Takuya Hayashi; Hidehiro Iida; Toshikazu Nakamura; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction.
Hypertension 2006;47(4):742-51.
2006: Takashi Miyake; Motokuni Aoki; H Nakashima; T Kawasaki; Masako Oishi; Kazusaburo Kataoka; Kazuo Tanemoto; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Prevention of abdominal aortic aneurysms by simultaneous inhibition of NFkappaB and ets using chimeric decoy oligonucleotides in a rabbit model.
Gene therapy 2006;13(8):695-704.
2006: Munehisa Shimamura; Naoyuki Sato; Shinichi Yoshimura; Yasufumi Kaneda; Ryuichi Morishita
HVJ-based non-viral gene transfer method: successful gene therapy using HGF and VEGF genes in experimental ischemia.
Frontiers in bioscience : a journal and virtual library 2006;11():753-9.
2005: Katsuto Tamai; Yasufumi Kaneda; Hiroshige Nakamura; Motohiro Aoki; Ryuichi Morishita; Koji Hashimoto; Akimichi Morita; Ichiro Katayama; Katsumi Hanada
[NFkappaB decoy DNA for treatment of atopic dermatitis].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():659-63.
2005: Hironori Nkagami; Yasufumi Kaneda; Ryuichi Morishita
[Future view of gene therapy in cardiovascular field].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():577-81.
2005: Yasufumi Kaneda
[Strategies for gene therapy].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():486-90.
2005: Yasufumi Kaneda
[Current status and future prospective of gene therapy].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():469-74.
2005: Hironori Nakagami; Kazuhisa Maeda; Ryuichi Morishita; Sota Iguchi; Tomoyuki Nishikawa; Yoichi Takami; Yasushi Kikuchi; Yukihiro Saito; Katsuto Tamai; Toshio Ogihara; Yasufumi Kaneda
Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2542-7.
2005: Munehisa Shimamura; Naoyuki Sato; Yoshiaki Taniyama; Hitomi Kurinami; Hiroyuki Tanaka; Toshihiro Takami; Toshio Ogihara; Masaya Tohyama; Yasufumi Kaneda; Ryuichi Morishita
Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles.
The journal of gene medicine 2005;7(11):1468-74.
2005: Tadashi Kimura; Hitomi Nakamura; Shinsuke Koyama; Kazuhide Ogita; Chisa Tabata; Tateki Tsutsui; Koichiro Shimoya; Masayasu Koyama; Yasufumi Kaneda; Yuji Murata
In vivo gene transfer into the mouse uterus: a powerful tool for investigating implantation physiology.
Journal of reproductive immunology 2005;67(1-2):13-20.
2005: Yukitoshi Shirakawa; Yoshiki Sawa; Yoshiaki Takewa; Eisuke Tatsumi; Yasufumi Kaneda; Yoshiyuki Taenaka; Hikaru Matsuda
Gene transfection with human hepatocyte growth factor complementary DNA plasmids attenuates cardiac remodeling after acute myocardial infarction in goat hearts implanted with ventricular assist devices.
The Journal of thoracic and cardiovascular surgery 2005;130(3):624-32.
2005: Makoto Ito; Seiji Yamamoto; Keisuke Nimura; Kazuya Hiraoka; Katsuto Tamai; Yasufumi Kaneda
Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin.
The journal of gene medicine 2005;7(8):1044-52.
2005: Ken Miwa; H Nakashima; Motokuni Aoki; Takashi Miyake; T Kawasaki; M Iwai; Masako Oishi; Kazusaburo Kataoka; Shigetsugu Ohgi; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Inhibition of ets, an essential transcription factor for angiogenesis, to prevent the development of abdominal aortic aneurysm in a rat model.
Gene therapy 2005;12(14):1109-18.
2005: Hidetoshi Mima; Ryuji Tomoshige; Toshihide Kanamori; Yasuhiko Tabata; Seiji Yamamoto; Susumu Ito; Katsuto Tamai; Yasufumi Kaneda
Biocompatible polymer enhances the in vitro and in vivo transfection efficiency of HVJ envelope vector.
The journal of gene medicine 2005;7(7):888-97.
2005: Norihisa Shigemura; Yoshiki Sawa; Shinya Mizuno; Masamichi Ono; Masato Minami; Meinoshin Okumura; Toshikazu Nakamura; Yasufumi Kaneda; Hikaru Matsuda
Induction of compensatory lung growth in pulmonary emphysema improves surgical outcomes in rats.
American journal of respiratory and critical care medicine 2005;171(11):1237-45.
2005: Hironori Nakagami; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita
Hepatocyte growth factor as potential cardiovascular therapy.
Expert review of cardiovascular therapy 2005;3(3):513-9.
2005: Hideaki Saeki; Keita Ohsumi; Hitoshi Aihara; Takashi Ito; Susumu Hirose; Kiyoe Ura; Yasufumi Kaneda
Linker histone variants control chromatin dynamics during early embryogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(16):5697-702.
2005: Masamichi Ono; Yoshiki Sawa; Yuji Miyamoto; Norihide Fukushima; Hajime Ichikawa; Toru Ishizaka; Yasufumi Kaneda; Hikaru Matsuda
The effect of gene transfer with hepatocyte growth factor for pulmonary vascular hypoplasia in neonatal porcine model.
The Journal of thoracic and cardiovascular surgery 2005;129(4):740-5.
2005: Norihisa Shigemura; Yoshiki Sawa; Shinya Mizuno; Masamichi Ono; Mitsunori Ohta; Toshikazu Nakamura; Yasufumi Kaneda; Hikaru Matsuda
Amelioration of pulmonary emphysema by in vivo gene transfection with hepatocyte growth factor in rats.
Circulation 2005;111(11):1407-14.
2005: Hironori Nakagami; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita
Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis.
Current diabetes reviews 2005;1(1):59-63.
2005: Yasufumi Kaneda; Seiji Yamamoto; Toshihiro Nakajima
Development of HVJ envelope vector and its application to gene therapy.
Advances in genetics 2005;53():307-32.
2004: Naruya Tomita; Haruhito Azuma; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita
Application of decoy oligodeoxynucleotides-based approach to renal diseases.
Current drug targets 2004;5(8):717-33.
2004: Kazuya Hiraoka; Seiji Yamamoto; Satoru Otsuru; Seiji Nakai; Katsuto Tamai; Ryuichi Morishita; Toshio Ogihara; Yasufumi Kaneda
Enhanced tumor-specific long-term immunity of hemagglutinating [correction of hemaggluttinating] virus of Japan-mediated dendritic cell-tumor fused cell vaccination by coadministration with CpG oligodeoxynucleotides.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4297-307.
2004: Munehisa Shimamura; Naoyuki Sato; Yoshiaki Taniyama; S Yamamoto; M Endoh; Hitomi Kurinami; Motokuni Aoki; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Development of efficient plasmid DNA transfer into adult rat central nervous system using microbubble-enhanced ultrasound.
Gene therapy 2004;11(20):1532-9.
2004: Hitomi Nakamura; Tadashi Kimura; Kazuhide Ogita; Shinsuke Koyama; Tomoko Tsujie; Tateki Tsutsui; Koichiro Shimoya; Masayasu Koyama; Yasufumi Kaneda; Yuji Murata
Alteration of the timing of implantation by in vivo gene transfer: delay of implantation by suppression of nuclear factor kappaB activity and partial rescue by leukemia inhibitory factor.
Biochemical and biophysical research communications 2004;321(4):886-92.
2004: Ryuichi Morishita; Motokuni Aoki; Naotaka Hashiya; Hirofumi Makino; Keita Yamasaki; Junya Azuma; Yoshiki Sawa; Hikaru Matsuda; Yasufumi Kaneda; Toshio Ogihara
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease.
Hypertension 2004;44(2):203-9.
2004: Naotaka Hashiya; Nobuo Jo; Motokuni Aoki; Kunio Matsumoto; Toshikazu Nakamura; Yasufumi Sato; Nahoko Ogata; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
In vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade.
Circulation 2004;109(24):3035-41.
2004: Keita Masuda; Seiji Yamamoto; Masayuki Endoh; Yasufumi Kaneda
Transposon-independent increase of transcription by the Sleeping Beauty transposase.
Biochemical and biophysical research communications 2004;317(3):796-800.
2004: Hironori Nakagami; Ryuichi Morishita; Tomoyuki Nishikawa; Hideo Shimizu; Sota Iguchi; Kunio Matsumoto; Toshikazu Nakamura; Yasufumi Kaneda; Toshio Ogihara
Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(5):359-65.
2004: Naruya Tomita; John Y S Kim; Gary H Gibbons; Lunan Zhang; Yasufumi Kaneda; Rolf A K Stahl; Malcom Ogborn; Benoit Venderville; Ryuichi Morishita; Dana Baran; Victor J Dzau
Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis.
International journal of molecular medicine 2004;13(5):629-36.
2004: Nobutaka Koibuchi; Yasufumi Kaneda; Yoshiaki Taniyama; Kunio Matsumoto; Toshikazu Nakamura; Toshio Ogihara; Ryuichi Morishita
Essential role of HGF (hepatocyte growth factor) in blood formation in Xenopus.
Blood 2004;103(9):3320-5.
2004: Ryuichi Morishita; Naruya Tomita; Yasufumi Kaneda; Toshio Ogihara
Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides.
Current opinion in pharmacology 2004;4(2):139-46.
2004: Atsushi Matsuki; Seiji Yamamoto; Hironori Nakagami; Motokuni Aoki; Katsuto Tamai; Kunio Matsumoto; Toshikazu Nakamura; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice.
Biochemical and biophysical research communications 2004;315(1):59-65.
2004: Yoshihiro Asano; Seiji Takashima; Masanori Asakura; Yasunori Shintani; Yulin Liao; Tetsuo Minamino; Hiroshi Asanuma; Shoji Sanada; Jiyoong Kim; Akiko Ogai; Tomi Fukushima; Yumiko Oikawa; Yasushi Okazaki; Yasufumi Kaneda; Manabu Sato; Jun-ichi Miyazaki; Soichiro Kitamura; Hitonobu Tomoike; Masafumi Kitakaze; Masatsugu Hori
Lamr1 functional retroposon causes right ventricular dysplasia in mice.
Nature genetics 2004;36(2):123-30.
2004: Munehisa Shimamura; Naoyuki Sato; Kazuo Oshima; Motokuni Aoki; Hitomi Kurinami; Satoshi Waguri; Yasuo Uchiyama; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model.
Circulation 2004;109(3):424-31.
2004: Hideki Nakashima; Motokuni Aoki; Takashi Miyake; Tomio Kawasaki; Masahiro Iwai; Nobuo Jo; Masako Oishi; Kazusaburo Kataoka; Shigetsugu Ohgi; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Inhibition of experimental abdominal aortic aneurysm in the rat by use of decoy oligodeoxynucleotides suppressing activity of nuclear factor kappaB and ets transcription factors.
Circulation 2004;109(1):132-8.
2004: Yoshiaki Taniyama; Naruya Tomita; Seiji Endoh; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita
[Gene transfer with ultrasound and microbubbles (optison) as a potential treatment for cardiovascular diseases].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2004;41(1):51-4.
2004: Kazuo Oshima; Munehisa Shimamura; Shinya Mizuno; Katsuto Tamai; Katsumi Doi; Ryuichi Morishita; Toshikazu Nakamura; Takeshi Kubo; Yasufumi Kaneda
Intrathecal injection of HVJ-E containing HGF gene to cerebrospinal fluid can prevent and ameliorate hearing impairment in rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):212-4.
2003: Kazuya Hiraoka; Hiromi Koike; Seiji Yamamoto; Naruya Tomita; Chieko Yokoyama; Tadashi Tanabe; Takashi Aikou; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Enhanced therapeutic angiogenesis by cotransfection of prostacyclin synthase gene or optimization of intramuscular injection of naked plasmid DNA.
Circulation 2003;108(21):2689-96.
2003: Satoru Yamazaki; Ryo Iwamoto; Kazuko Saeki; Masanori Asakura; Seiji Takashima; Ayano Yamazaki; Rina Kimura; Hiroto Mizushima; Hiroki Moribe; Shigeki Higashiyama; Masayuki Endoh; Yasufumi Kaneda; Satoshi Takagi; Satoshi Itami; Naoki Takeda; Gen Yamada; Eisuke Mekada
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities.
The Journal of cell biology 2003;163(3):469-75.
2003: Tsunetatsu Namba; Hiromi Koike; Kazushi Murakami; Motokuni Aoki; Hirofumi Makino; Naotaka Hashiya; Toshio Ogihara; Yasufumi Kaneda; Masakazu Kohno; Ryuichi Morishita
Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model.
Circulation 2003;108(18):2250-7.
2003: Yasufumi Kaneda
New vector innovation for drug delivery: development of fusigenic non-viral particles.
Current drug targets 2003;4(8):599-602.
2003: Hitomi Nakamura; Tadashi Kimura; Hiroyuki Ikegami; Kazuhide Ogita; Shinsuke Koyama; Koichiro Shimoya; Tomoko Tsujie; Masayasu Koyama; Yasufumi Kaneda; Yuji Murata
Highly efficient and minimally invasive in-vivo gene transfer to the mouse uterus using haemagglutinating virus of Japan (HVJ) envelope vector.
Molecular human reproduction 2003;9(10):603-9.
2003: Kazuya Hiraoka; Yasufumi Kaneda
[Gene therapy for colorectal cancer in clinical trials].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():522-5.
2003: Chisaki Ishida; Kiyoe Ura; Akiko Hirao; Hiroyuki Sasaki; Atsushi Toyoda; Yoshiyuki Sakaki; Hitoshi Niwa; En Li; Yasufumi Kaneda
Genomic organization and promoter analysis of the Dnmt3b gene.
Gene 2003;310():151-9.
2003: Kazunori Taniguchi; Koji Umeshita; Masato Sakon; Hideyuki Miyoshi; Masaru Tokunaga; Hideo Ariyoshi; Tomoki Yamano; Yasufumi Kaneda; Morito Monden
Suppression of oxidative stress-induced hepatocyte injury by calpain antisense.
The Journal of surgical research 2003;111(1):23-7.
2003: Naruya Tomita; Haruhito Azuma; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita
Gene therapy with transcription factor decoy oligonucleotides as a potential treatment for cardiovascular diseases.
Current drug targets 2003;4(4):339-46.
2003: Yasufumi Kaneda; Katsuto Tamai
Current status and future prospects of gene therapy technologies toward the treatment of intractable skin diseases.
Archives of dermatological research 2003;295 Suppl 1():S63-6.
2003: Hiromi Koike; Ryuichi Morishita; Sota Iguchi; Motokuni Aoki; Kunio Matsumoto; Toshikazu Nakamura; Chieko Yokoyama; Tadashi Tanabe; Toshio Ogihara; Yasufumi Kaneda
Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):779-81.
2003: Naruya Tomita; Ryuichi Morishita; Yoshiaki Taniyama; Hiromi Koike; Motokuni Aoki; Hideo Shimizu; Kunio Matsumoto; Toshikazu Nakamura; Yasufumi Kaneda; Toshio Ogihara
Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1.
Circulation 2003;107(10):1411-7.
2003: Seiji Yamamoto; Tomoki Yamano; Maki Tanaka; Dave S B Hoon; Sonshin Takao; Ryuichi Morishita; Takashi Aikou; Yasufumi Kaneda
A novel combination of suicide gene therapy and histone deacetylase inhibitor for treatment of malignant melanoma.
Cancer gene therapy 2003;10(3):179-86.
2003: Keita Yamasaki; T Asai; M Shimizu; Motokuni Aoki; Naotaka Hashiya; H Sakonjo; Hirofumi Makino; Yasufumi Kaneda; Toshio Ogihara; Ryuichi Morishita
Inhibition of NFkappaB activation using cis-element 'decoy' of NFkappaB binding site reduces neointimal formation in porcine balloon-injured coronary artery model.
Gene therapy 2003;10(4):356-64.
2003: Youichi Saitoh; Amami Kato; Yasushi Hagihara; Yasufumi Kaneda; Toshiki Yoshimine
Gene therapy for ischemic brain diseases.
Current gene therapy 2003;3(1):49-58.
2003: Munehisa Shimamura; Ryuichi Morishita; Masayuki Endoh; Kazuo Oshima; Motokuni Aoki; Satoshi Waguri; Yasuo Uchiyama; Yasufumi Kaneda
HVJ-envelope vector for gene transfer into central nervous system.
Biochemical and biophysical research communications 2003;300(2):464-71.
2003: Yasufumi Kaneda; Seiji Yamamoto; Kazuya Hiraoka
The hemagglutinating virus of Japan-liposome method for gene delivery.
Methods in enzymology 2003;373():482-93.
2003: Ryuichi Morishita; Yasufumi Kaneda; Toshio Ogihara
Therapeutic potential of oligonucleotide-based therapy in cardiovascular disease.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2003;17(6):383-9.
2003: M Nakabayashi; Ryuichi Morishita; Hironori Nakagami; K Kuba; Kunihiro Matsumoto; Tadashi Nakamura; Yasuo Tano; Yasufumi Kaneda
HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model.
Diabetologia 2003;46(1):115-23.
2002: Masamichi Ono; Yoshiki Sawa; Kunio Matsumoto; Toshikazu Nakamura; Yasufumi Kaneda; Hikaru Matsuda
In vivo gene transfection with hepatocyte growth factor via the pulmonary artery induces angiogenesis in the rat lung.
Circulation 2002;106(12 Suppl 1):I264-9.
2002: Naruya Tomita; Ryuichi Morishita; Kei Yamamoto; Jitsuo Higaki; Victor J Dzau; Toshio Ogihara; Yasufumi Kaneda
Targeted gene therapy for rat glomerulonephritis using HVJ-immunoliposomes.
The journal of gene medicine 2002;4(5):527-35.
2002: Hideji Nakamura; Motokuni Aoki; Katsuto Tamai; Masako Oishi; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Prevention and regression of atopic dermatitis by ointment containing NF-kB decoy oligodeoxynucleotides in NC/Nga atopic mouse model.
Gene therapy 2002;9(18):1221-9.
2002: Yasufumi Kaneda; Toshihiro Nakajima; Tomoyuki Nishikawa; Seiji Yamamoto; Hiroyuki Ikegami; Naho Suzuki; Hitomi Nakamura; Ryuichi Morishita; Hitoshi Kotani
Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):219-26.
2002: Hironori Nakagami; Ryuichi Morishita; Kei Yamamoto; Yoshiaki Taniyama; Motokuni Aoki; Keita Yamasaki; Kunio Matsumoto; Toshikazu Nakamura; Yasufumi Kaneda; Toshio Ogihara
Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane.
Diabetes 2002;51(8):2604-11.
2002: Naruya Tomita; Ryuichi Morishita; Hiromi Koike; Masahide Hashizume; Mitsue Notake; Buichi Fujitani; Yasufumi Kaneda; Masatsugu Horiuchi; Toshio Ogihara
Therapeutic approach to familial hypercholesterolemia by HVJ-liposomes in LDL receptor knockout mouse.
International journal of molecular medicine 2002;10(2):137-43.
2002: Yoshiaki Taniyama; Ryuichi Morishita; Motokuni Aoki; Kazuya Hiraoka; Keita Yamasaki; Naotaka Hashiya; Kunio Matsumoto; Toshikazu Nakamura; Yasufumi Kaneda; Toshio Ogihara
Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy.
Hypertension 2002;40(1):47-53.
2002: Masaki Mori; Hironori Nakagami; Ryuichi Morishita; Noriaki Mitsuda; Kei Yamamoto; Shin-ichi Yoshimura; Nobutaka Ohkubo; Naoyuki Sato; Toshio Ogihara; Yasufumi Kaneda
N141I mutant presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression.
Life sciences 2002;70(21):2567-80.
2002: Tadashi Nakamura; Ryuichi Morishita; T Asai; N Tsuboniwa; Motokuni Aoki; H Sakonjo; Keita Yamasaki; Naotaka Hashiya; Yasufumi Kaneda; Toshio Ogihara
Molecular strategy using cis-element 'decoy' of E2F binding site inhibits neointimal formation in porcine balloon-injured coronary artery model.
Gene therapy 2002;9(8):488-94.
2002: Ryuichi Morishita; Minako Sakaki; Kei Yamamoto; Sota Iguchi; Motokuni Aoki; Keita Yamasaki; Kunio Matsumoto; Toshikazu Nakamura; Richard Lawn; Toshio Ogihara; Yasufumi Kaneda
Impairment of collateral formation in lipoprotein(a) transgenic mice: therapeutic angiogenesis induced by human hepatocyte growth factor gene.
Circulation 2002;105(12):1491-6.
2002: Yoshiaki Taniyama; K Tachibana; Kazuya Hiraoka; Motokuni Aoki; Seiji Yamamoto; Kunihiro Matsumoto; Tadashi Nakamura; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle.
Gene therapy 2002;9(6):372-80.
2002: Yasufumi Kaneda
Viral liposomes. Preparation and use.
Methods in molecular medicine 2002;69():63-72.
2002: Hiroshige Nakamura; Ryuichi Morishita; Yasufumi Kaneda
Molecular therapy via transcriptional regulation with double-stranded oligodeoxynucleotides as decoys.
In vivo (Athens, Greece) 2002;16(1):45-8.
2002: Ryuichi Morishita; Yasufumi Kaneda
HVJ (hemagglutinating virus of Japan; Sendai virus)-liposome method.
Methods in enzymology 2002;346():619-27.
2001: Ryuichi Morishita; Motokuni Aoki; Yasufumi Kaneda
Decoy oligodeoxynucleotides as novel cardiovascular drugs for cardiovascular disease.
Annals of the New York Academy of Sciences 2001;947():294-301; discussion 301-2.
2001: Yoshiaki Taniyama; Ryuichi Morishita; Kazuya Hiraoka; Motokuni Aoki; Hironori Nakagami; Keita Yamasaki; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic hind limb ischemia model: molecular mechanisms of delayed angiogenesis in diabetes.
Circulation 2001;104(19):2344-50.
2001: T Miyata; Seiji Yamamoto; K Sakamoto; Ryuichi Morishita; Yasufumi Kaneda
Novel immunotherapy for peritoneal dissemination of murine colon cancer with macrophage inflammatory protein-1beta mediated by a tumor-specific vector, HVJ cationic liposomes.
Cancer gene therapy 2001;8(11):852-60.
2001: T Ueno; Yoshiki Sawa; Satoru Kitagawa-Sakakida; Motonobu Nishimura; R Morishita; Yasufumi Kaneda; E Kohmura; Toshiki Yoshimine; Hikaru Matsuda
Nuclear factor-kappa B decoy attenuates neuronal damage after global brain ischemia: a future strategy for brain protection during circulatory arrest.
The Journal of thoracic and cardiovascular surgery 2001;122(4):720-7.
2001: M Wataya-Kaneda; Yasufumi Kaneda; Okio Hino; H Adachi; Y Hirayama; K Seyama; T Satou; Kunihiko Yoshikawa
Cells derived from tuberous sclerosis show a prolonged S phase of the cell cycle and increased apoptosis.
Archives of dermatological research 2001;293(9):460-9.
2001: Y Kobayashi; Norihide Fukushima; Yoshiki Sawa; Shigeaki Ohtake; Goro Matsumiya; Kei Horiguchi; N Kawaguchi; N Matsuura; Yasufumi Kaneda; Hikaru Matsuda
Effects of gene transfection of human bcl-2 on concordant cardiac xenografts in hamster to rat model.
The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi 2001;49(9):570-5.
2001: Ryuichi Morishita; Motokuni Aoki; Yasufumi Kaneda; Toshio Ogihara
Gene therapy in vascular medicine: recent advances and future perspectives.
Pharmacology & therapeutics 2001;91(2):105-14.
2001: Motokuni Aoki; Ryuichi Morishita; Seiji Hayashi; Nobuo Jo; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model.
Diabetologia 2001;44(8):1034-42.
2001: K Kaneko; Masahiko Yano; Tomoki Yamano; T Tsujinaka; Hiroaki Miki; Y Akiyama; Masahiko Taniguchi; Yoshiyuki Fujiwara; Yuichiro Doki; Masahiro Inoue; Hitoshi Shiozaki; Yasufumi Kaneda; Morito Monden
Detection of peritoneal micrometastases of gastric carcinoma with green fluorescent protein and carcinoembryonic antigen promoter.
Cancer research 2001;61(14):5570-4.
2001: T Otomo; Satoru Yamamoto; Ryuichi Morishita; Yasufumi Kaneda
EBV replicon vector system enhances transgene expression in vivo: applications to cancer gene therapy.
The journal of gene medicine 2001;3(4):345-52.
2001: Motokuni Aoki; T Nata; Ryuichi Morishita; H Matsushita; Hironori Nakagami; Kazuhiro Yamamoto; K Yamazaki; M Nakabayashi; Toshio Ogihara; Yasufumi Kaneda
Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: antiapoptotic effect of antioxidant agents on endothelial cells.
Hypertension 2001;38(1):48-55.
2001: Hironori Nakagami; Ryuichi Morishita; Kazuhiro Yamamoto; S I Yoshimura; Yoshiaki Taniyama; Motokuni Aoki; H Matsubara; S Kim; Yasufumi Kaneda; Toshio Ogihara
Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells.
Diabetes 2001;50(6):1472-81.
2001: Kazuhiro Yamamoto; Ryuichi Morishita; Seiji Hayashi; H Matsushita; Hironori Nakagami; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells.
Hypertension 2001;37(5):1341-8.
2001: Kiyoe Ura; Marito Araki; Hideaki Saeki; Chikahide Masutani; Takashi Ito; Shigenori Iwai; T Mizukoshi; Yasufumi Kaneda; Fumio Hanaoka
ATP-dependent chromatin remodeling facilitates nucleotide excision repair of UV-induced DNA lesions in synthetic dinucleosomes.
The EMBO journal 2001;20(8):2004-14.
2001: M Tsujie; Yoshitaka Isaka; Hideji Nakamura; Yasufumi Kaneda; Enyu Imai; Masatsugu Hori
Prolonged transgene expression in glomeruli using an EBV replicon vector system combined with HVJ liposomes.
Kidney international 2001;59(4):1390-6.
2001: N Tsuboniwa; Ryuichi Morishita; T Hirano; J Fujimoto; S Furukawa; M Kikumori; Akihiko Okuyama; Yasufumi Kaneda
Safety evaluation of hemagglutinating virus of Japan--artificial viral envelope liposomes in nonhuman primates.
Human gene therapy 2001;12(5):469-87.
2001: Yoshiaki Taniyama; Ryuichi Morishita; Motokuni Aoki; Hironori Nakagami; Kazuhiro Yamamoto; K Yamazaki; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease.
Gene therapy 2001;8(3):181-9.
2001: T Sakaguchi; Yoshiki Sawa; Norihide Fukushima; Motonobu Nishimura; Hajime Ichikawa; Yasufumi Kaneda; Hikaru Matsuda
A novel strategy of decoy transfection against nuclear factor-kappaB in myocardial preservation.
The Annals of thoracic surgery 2001;71(2):624-9; discussion 629-30.
2001: Hironori Nakagami; Ryuichi Morishita; Kazuhiro Yamamoto; Yoshiaki Taniyama; Motokuni Aoki; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; M Horiuchi; Toshio Ogihara
Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells.
Hypertension 2001;37(2 Pt 2):581-6.
2001: Yasufumi Kaneda
Improvements in gene therapy technologies.
Molecular urology 2001;5(2):85-9.
2001: Naruya Tomita; Ryuichi Morishita; S Tomita; Yasufumi Kaneda; J Higaki; Toshio Ogihara; M Horiuchi
Inhibition of TNF-alpha, induced cytokine and adhesion molecule. Expression in glomerular cells in vitro and in vivo by transcription factor decoy for NFkappaB.
Experimental nephrology 2001;9(3):181-90.
2001: H Kanyama; Naruya Tomita; Tomoki Yamano; T Aihara; Yasuo Miyoshi; Masayuki Ohue; Mitsugu Sekimoto; Isao Sakita; Yasuhiro Tamaki; Yasufumi Kaneda; P D Senter; Morito Monden
Usefulness of repeated direct intratumoral gene transfer using hemagglutinating virus of Japan-liposome method for cytosine deaminase suicide gene therapy.
Cancer research 2001;61(1):14-8.
2000: Toshiki Takahashi; Tadashi Nakamura; Atsushi Hayashi; Motohiro Kamei; Masao Nakabayashi; Akira Okada; Naruya Tomita; Yasufumi Kaneda; Yasuo Tano
Inhibition of experimental choroidal neovascularization by overexpression of tissue inhibitor of metalloproteinases-3 in retinal pigment epithelium cells.
American journal of ophthalmology 2000;130(6):774-81.
2000: Haruhiko Kamada; Yasuo Tsutsumi; Yoko Yamamoto; Tetsuya Kihira; Yasufumi Kaneda; Yu Mu; Hiroshi Kodaira; Shin-ichi Tsunoda; Shinsaku Nakagawa; Tadanori Mayumi
Antitumor activity of tumor necrosis factor-alpha conjugated with polyvinylpyrrolidone on solid tumors in mice.
Cancer research 2000;60(22):6416-20.
2000: Yoshitaka Isaka; M Tsujie; Y Ando; Hideji Nakamura; Yasufumi Kaneda; Enyu Imai; Masatsugu Hori
Transforming growth factor-beta 1 antisense oligodeoxynucleotides block interstitial fibrosis in unilateral ureteral obstruction.
Kidney international 2000;58(5):1885-92.
2000: Noritoshi Nagaya; Chieko Yokoyama; Shingo Kyotani; Manabu Shimonishi; Ryuichi Morishita; Masaaki Uematsu; T Nishikimi; Norifumi Nakanishi; Toshio Ogihara; M Yamagishi; Kunio Miyatake; Yasufumi Kaneda; Tadashi Tanabe
Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.
Circulation 2000;102(16):2005-10.
2000: K Hayashi; Shun Nakamura; Ryuichi Morishita; Atsushi Moriguchi; Motokuni Aoki; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Naohiko Sakai; Toshio Ogihara
In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model.
Gene therapy 2000;7(19):1664-71.
2000: Yasufumi Kaneda
Virosomes: evolution of the liposome as a targeted drug delivery system.
Advanced drug delivery reviews 2000;43(2-3):197-205.
2000: Kazuhiro Yamamoto; Ryuichi Morishita; Naruya Tomita; T Shimozato; Hironori Nakagami; A Kikuchi; Motokuni Aoki; Jitsuo Higaki; Yasufumi Kaneda; Toshio Ogihara
Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model: potential application of ribozyme strategy to treat cardiovascular disease.
Circulation 2000;102(11):1308-14.
2000: Shin-ichi Tsunoda; Haruhiko Kamada; Yoko Yamamoto; T Ishikawa; J Matsui; Keiichi Koizumi; Yasufumi Kaneda; Yasuo Tsutsumi; Yoshiyuki Ohsugi; T Hirano; Tadanori Mayumi
Molecular design of polyvinylpyrrolidone-conjugated interleukin-6 for enhancement of in vivo thrombopoietic activity in mice.
Journal of controlled release : official journal of the Controlled Release Society 2000;68(3):335-41.
2000: Naruya Tomita; Ryuichi Morishita; S Tomita; Gary H Gibbons; L Zhang; M Horiuchi; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara; Victor J Dzau
Transcription factor decoy for NFkappaB inhibits TNF-alpha-induced cytokine and adhesion molecule expression in vivo.
Gene therapy 2000;7(15):1326-32.
2000: Ryuichi Morishita; Gary H Gibbons; Yasufumi Kaneda; Toshio Ogihara; Victor J Dzau
Systemic administration of HVJ viral coat-liposome complex containing human insulin vector decreases glucose level in diabetic mouse: A model of gene therapy.
Biochemical and biophysical research communications 2000;273(2):666-74.
2000: Ryuichi Morishita; Motokuni Aoki; Yasufumi Kaneda
Oligonucleotide-based gene therapy for cardiovascular disease: are oligonucleotide therapeutics novel cardiovascular drugs?
Current drug targets 2000;1(1):15-23.
2000: Naruya Tomita; Ryuichi Morishita; H Y Lan; Kazuhiro Yamamoto; M Hashizume; M Notake; K Toyosawa; Buichi Fujitani; W Mu; D J Nikolic-Paterson; R C Atkins; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
In vivo administration of a nuclear transcription factor-kappaB decoy suppresses experimental crescentic glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2000;11(7):1244-52.
2000: Tomoki Yamano; Kiyoe Ura; Ryuichi Morishita; H Nakajima; Morito Monden; Yasufumi Kaneda
Amplification of transgene expression in vitro and in vivo using a novel inhibitor of histone deacetylase.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(6):574-80.
2000: Kiyoe Ura; Yasufumi Kaneda
[DNA methylation and chromatin modification on transcription].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1465-72.
2000: Ryuichi Morishita; Motokuni Aoki; Shun Nakamura; Jitsuo Higaki; Yasufumi Kaneda; Toshio Ogihara
Gene therapy for cardiovascular disease using hepatocyte growth factor.
Annals of the New York Academy of Sciences 2000;902():369-76.
2000: Yoshihisa Hagihara; Youichi Saitoh; Yasufumi Kaneda; E Kohmura; Toshiki Yoshimine
Widespread gene transfection into the central nervous system of primates.
Gene therapy 2000;7(9):759-63.
2000: M Tsujie; Yoshitaka Isaka; Y Ando; Yoshitaka Akagi; Yasufumi Kaneda; N Ueda; Enyu Imai; Masatsugu Hori
Gene transfer targeting interstitial fibroblasts by the artificial viral envelope-type hemagglutinating virus of Japan liposome method.
Kidney international 2000;57(5):1973-80.
2000: Toru Arai; Kin'ya Abe; Hiroaki Matsuoka; Masasuke Yoshida; Masahide Mori; Sho Goya; Hiroshi Kida; Kazumi Nishino; Tadashi Osaki; Isao Tachibana; Yasufumi Kaneda; Seiji Hayashi
Introduction of the interleukin-10 gene into mice inhibited bleomycin-induced lung injury in vivo.
American journal of physiology. Lung cellular and molecular physiology 2000;278(5):L914-22.
2000: Ryuichi Morishita; Gary H Gibbons; Naruya Tomita; L Zhang; Yasufumi Kaneda; Toshio Ogihara; Victor J Dzau
Antisense oligodeoxynucleotide inhibition of vascular angiotensin-converting enzyme expression attenuates neointimal formation: evidence for tissue angiotensin-converting enzyme function.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):915-22.
2000: H Matsushita; Ryuichi Morishita; Motokuni Aoki; Naruya Tomita; Yoshiaki Taniyama; Hironori Nakagami; T Shimozato; Jitsuo Higaki; Yasufumi Kaneda; Toshio Ogihara
Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells.
Circulation 2000;101(12):1447-52.
2000: Motokuni Aoki; Ryuichi Morishita; Yoshiaki Taniyama; Iwao Kida; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets.
Gene therapy 2000;7(5):417-27.
2000: Yasufumi Kaneda; Yukihiko Saeki; Masao Nakabayashi; WZ Zhou; M W Kaneda; Ryuichi Morishita
Enhancement of transgene expression by cotransfection of oriP plasmid with EBNA-1 expression vector.
Human gene therapy 2000;11(3):471-9.
2000: J Sakuma-Mochizuki; Masasuke Yoshida; Kin'ya Abe; Toru Arai; Masahide Mori; Yasufumi Kaneda; Seiji Hayashi
Changes in pulmonary histology and exfoliated bronchoalveolar cells induced by in vivo introduction of the tumor necrosis factor-alpha gene.
Inflammation 2000;24(1):11-9.
2000: Jitsuo Higaki; M Aoki; Ryuichi Morishita; Iwao Kida; Y Taniyama; Naruya Tomita; K Yamamoto; Atsushi Moriguchi; Yasufumi Kaneda; Toshio Ogihara
In vivo evidence of the importance of cardiac angiotensin-converting enzyme in the pathogenesis of cardiac hypertrophy.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):428-34.
2000: Motokuni Aoki; Ryuichi Morishita; Yoshiaki Taniyama; Yasufumi Kaneda; Toshio Ogihara
Therapeutic angiogenesis induced by hepatocyte growth factor: potential gene therapy for ischemic diseases.
Journal of atherosclerosis and thrombosis 2000;7(2):71-6.
1999: Tetsuya Tomita; Eiji Takeuchi; Naruya Tomita; Ryuichi Morishita; Motoharu Kaneko; Kazuhiro Yamamoto; Takanobu Nakase; H Seki; K Kato; Yasufumi Kaneda; Takahiro Ochi
Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapy.
Arthritis and rheumatism 1999;42(12):2532-42.
1999: Masasuke Yoshida; J Sakuma-Mochizuki; Kin'ya Abe; Toru Arai; Masahide Mori; Sho Goya; Hiroaki Matsuoka; Seiji Hayashi; Yasufumi Kaneda; Tadamitsu Kishimoto
In vivo gene transfer of an extracellular domain of platelet-derived growth factor beta receptor by the HVJ-liposome method ameliorates bleomycin-induced pulmonary fibrosis.
Biochemical and biophysical research communications 1999;265(2):503-8.
1999: WZ Zhou; Dave S B Hoon; S K Huang; S Fujii; K Hashimoto; Ryuichi Morishita; Yasufumi Kaneda
RNA melanoma vaccine: induction of antitumor immunity by human glycoprotein 100 mRNA immunization.
Human gene therapy 1999;10(16):2719-24.
1999: K Suzuki; Yoshiki Sawa; Hajime Ichikawa; Yasufumi Kaneda; Hikaru Matsuda
Myocardial protection with endogenous overexpression of manganese superoxide dismutase.
The Annals of thoracic surgery 1999;68(4):1266-71.
1999: WZ Zhou; Yasufumi Kaneda; S Huang; Ryuichi Morishita; Dave S B Hoon
Protective immunization against melanoma by gp100 DNA-HVJ-liposome vaccine.
Gene therapy 1999;6(10):1768-73.
1999: Yasufumi Kaneda; Ryuichi Morishita
[Gene therapy of cardiovascular disorders].
Human cell 1999;12(3):109-14.
1999: Y Kawahira; Yoshiki Sawa; Motonobu Nishimura; Satoru Kitagawa-Sakakida; H Ueda; Yasufumi Kaneda; Hikaru Matsuda
Gene transfection of beta 2-adrenergic receptor into the normal rat heart enhances cardiac response to beta-adrenergic agonist.
The Journal of thoracic and cardiovascular surgery 1999;118(3):446-51.
1999: T Nishii; A Moriguchi; Ryuichi Morishita; K Yamada; S Nakamura; N Tomita; Yasufumi Kaneda; A Fukamizu; H Mikami; Jitsuo Higaki; Toshio Ogihara
Angiotensinogen gene-activating elements regulate blood pressure in the brain.
Circulation research 1999;85(3):257-63.
1999: Shun Nakamura; Atsushi Moriguchi; Ryuichi Morishita; K Yamada; T Nishii; Naruya Tomita; Mitsuru Ohishi; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Activation of the brain angiotensin system by in vivo human angiotensin-converting enzyme gene transfer in rats.
Hypertension 1999;34(2):302-8.
1999: Motokuni Aoki; Ryuichi Morishita; H Matsushita; Seiji Hayashi; Hironori Nakagami; Kazuhiro Yamamoto; Atsushi Moriguchi; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells. Potential role of p53 in regulation of vascular smooth muscle cell growth.
Hypertension 1999;34(2):192-200.
1999: Yasufumi Kaneda; Yukihiko Saeki; Ryuichi Morishita
Gene therapy using HVJ-liposomes: the best of both worlds?
Molecular medicine today 1999;5(7):298-303.
1999: H Ueda; Yoshiki Sawa; Kunihiro Matsumoto; Satoru Kitagawa-Sakakida; Y Kawahira; Tadashi Nakamura; Yasufumi Kaneda; Hikaru Matsuda
Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart.
The Annals of thoracic surgery 1999;67(6):1726-31.
1999: Haruhiko Kamada; Yasuo Tsutsumi; Shin-ichi Tsunoda; Tetsuya Kihira; Yasufumi Kaneda; Yoko Yamamoto; Shinsaku Nakagawa; Y Horisawa; Tadanori Mayumi
Molecular design of conjugated tumor necrosis factor-alpha: synthesis and characteristics of polyvinyl pyrrolidone modified tumor necrosis factor-alpha.
Biochemical and biophysical research communications 1999;257(2):448-53.
1999: Mitsunobu Sato; Yukihiko Saeki; Keiichi Tanaka; Yasufumi Kaneda
Ribosome-associated protein LBP/p40 binds to S21 protein of 40S ribosome: analysis using a yeast two-hybrid system.
Biochemical and biophysical research communications 1999;256(2):385-90.
1999: Yu Mu; Haruhiko Kamada; Yasufumi Kaneda; Yoko Yamamoto; Hiroshi Kodaira; Shin-ichi Tsunoda; Yasuo Tsutsumi; Mitsuko Maeda; Koichi Kawasaki; M Nomizu; Yoshihiro Yamada; Tadanori Mayumi
Bioconjugation of laminin peptide YIGSR with poly(styrene co-maleic acid) increases its antimetastatic effect on lung metastasis of B16-BL6 melanoma cells.
Biochemical and biophysical research communications 1999;255(1):75-9.
1999: Yoshitaka Isaka; Yoshitaka Akagi; Y Ando; M Tsujie; T Sudo; N Ohno; Wayne A Border; Nancy A Noble; Yasufumi Kaneda; Masatsugu Hori; Enyu Imai
Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis.
Kidney international 1999;55(2):465-75.
1999: Tatemi Todaka; Chieko Yokoyama; Hiroji Yanamoto; Nobuo Hashimoto; Izumi Nagata; T Tsukahara; Shuntaro Hara; Toshihisa Hatae; Ryuichi Morishita; Motokuni Aoki; Toshio Ogihara; Yasufumi Kaneda; Tadashi Tanabe
Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats.
Stroke; a journal of cerebral circulation 1999;30(2):419-26.
1999: Masasuke Yoshida; Seiji Hayashi; J Sakuma-Mochizuki; Kin'ya Abe; Toru Arai; Masahide Mori; Sho Goya; Hiroaki Matsuoka; Yasufumi Kaneda; Tadamitsu Kishimoto
Introduction of plasmid DNA and oligonucleotides into lung epithelial cells by the hemagglutinating virus of Japan (HVJ)-liposome method.
Somatic cell and molecular genetics 1999;25(1):49-57.
1999: Yasufumi Kaneda
Development of a novel fusogenic viral liposome system (HVJ-liposomes) and its applications to the treatment of acquired diseases.
Molecular membrane biology 1999;16(1):119-22.
1999: I Ozkan; Konsei Shino; Norimasa Nakamura; T Natsuume; Norinao Matsumoto; Shuji Horibe; Tetsuya Tomita; Yasufumi Kaneda; Takahiro Ochi
Direct in vivo gene transfer to healing rat patellar ligament by intra-arterial delivery of haemagglutinating virus of Japan liposomes.
European journal of clinical investigation 1999;29(1):63-7.
1998: Kayoko Kinoshita; Yasufumi Kaneda; Mitsunobu Sato; Yukihiko Saeki; M Wataya-Kaneda; A Hoffmann
LBP-p40 binds DNA tightly through associations with histones H2A, H2B, and H4.
Biochemical and biophysical research communications 1998;253(2):277-82.
1998: Y Kawahira; Yoshiki Sawa; Motonobu Nishimura; Satoru Kitagawa-Sakakida; H Ueda; Yasufumi Kaneda; Hikaru Matsuda
In vivo transfer of a beta 2-adrenergic receptor gene into the pressure-overloaded rat heart enhances cardiac response to beta-adrenergic agonist.
Circulation 1998;98(19 Suppl):II262-7; discussion II267-8.
1998: Ryuichi Morishita; Shingo Yamada; Kazuhiro Yamamoto; Naruya Tomita; Iwao Kida; Ikunosuke Sakurabayashi; A Kikuchi; Yasufumi Kaneda; R Lawn; Jitsuo Higaki; Toshio Ogihara
Novel therapeutic strategy for atherosclerosis: ribozyme oligonucleotides against apolipoprotein(a) selectively inhibit apolipoprotein(a) but not plasminogen gene expression.
Circulation 1998;98(18):1898-904.
1998: Yoshiki Sawa; Yasufumi Kaneda; HZ Bai; K Suzuki; J Fujimoto; Ryuichi Morishita; Hikaru Matsuda
Efficient transfer of oligonucleotides and plasmid DNA into the whole heart through the coronary artery.
Gene therapy 1998;5(11):1472-80.
1998: Norimasa Nakamura; Konsei Shino; T Natsuume; Shuji Horibe; Norinao Matsumoto; Yasufumi Kaneda; Takahiro Ochi
Early biological effect of in vivo gene transfer of platelet-derived growth factor (PDGF)-B into healing patellar ligament.
Gene therapy 1998;5(9):1165-70.
1998: HZ Bai; Yoshiki Sawa; W D Zhang; T Yamakawa; Ryuichi Morishita; Yasufumi Kaneda; Hikaru Matsuda
Gene transfer to vein graft wall by HVJ-liposome method: time course and localization of gene expression.
The Annals of thoracic surgery 1998;66(3):814-9; discussion 819-20.
1998: Ryuichi Morishita; Kazuhiro Yamamoto; Shingo Yamada; H Matsushita; Naruya Tomita; Ikunosuke Sakurabayashi; Yasufumi Kaneda; Atsushi Moriguchi; Jitsuo Higaki; Toshio Ogihara
Stimulatory effect of lipoprotein (a) on proliferation of human mesangial cells: role of lipoprotein (a) in renal disease.
Biochemical and biophysical research communications 1998;249(2):313-20.
1998: Yukihiko Saeki; M Wataya-Kaneda; Keiichi Tanaka; Yasufumi Kaneda
Sustained transgene expression in vitro and in vivo using an Epstein-Barr virus replicon vector system combined with HVJ liposomes.
Gene therapy 1998;5(8):1031-7.
1998: Ryuichi Morishita; Shingo Yamada; Jitsuo Higaki; Naruya Tomita; Iwao Kida; Motokuni Aoki; Atsushi Moriguchi; Seiji Hayashi; Ikunosuke Sakurabayashi; Yasufumi Kaneda; Toshio Ogihara
Conditioned medium from HepG2 cells transfected with human apolipoprotein(a) gene stimulates growth of human vascular smooth muscle cells: effects of overexpression of human apolipoprotein(a) gene.
Hypertension 1998;32(2):215-22.
1998: H Bai; Ryuichi Morishita; Iwao Kida; T Yamakawa; W Zhang; Motokuni Aoki; H Matsushita; A Noda; R Nagai; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara; Yoshiki Sawa; Hikaru Matsuda
Inhibition of intimal hyperplasia after vein grafting by in vivo transfer of human senescent cell-derived inhibitor-1 gene.
Gene therapy 1998;5(6):761-9.
1998: K Suzuki; Yoshiki Sawa; Yasufumi Kaneda; H Ichikawa; R Shirakura; Hikaru Matsuda
Overexpressed heat shock protein 70 attenuates hypoxic injury in coronary endothelial cells.
Journal of molecular and cellular cardiology 1998;30(6):1129-36.
1998: Yoshitaka Isaka; Yoshitaka Akagi; Yasufumi Kaneda; Enyu Imai
The HVJ liposome method.
Experimental nephrology 1998;6(2):144-7.
1998: K Suzuki; Yoshiki Sawa; Yasufumi Kaneda; H Ichihara; Ryota Shirakura; Hikaru Matsuda
[In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat].
Journal of cardiology 1998;31(3):187-8.
1998: Yasufumi Kaneda; Yoko Yamamoto; Haruhiko Kamada; Shin-ichi Tsunoda; Yasuo Tsutsumi; Toshio Hirano; Tadanori Mayumi
Antitumor activity of tumor necrosis factor alpha conjugated with divinyl ether and maleic anhydride copolymer on solid tumors in mice.
Cancer research 1998;58(2):290-5.
1998: Yasufumi Kaneda; Kayoko Kinoshita; Mitsunobu Sato; Yukihiko Saeki; R Yamada; M Wataya-Kaneda; Keiichi Tanaka
The induction of apoptosis in HeLa cells by the loss of LBP-p40.
Cell death and differentiation 1998;5(1):20-8.
1998: Enyu Imai; Yoshitaka Isaka; Yoshitaka Akagi; Yasufumi Kaneda; Masatsugu Hori
Gene transfer and kidney disease.
Journal of nephrology 1998;11(1):16-9.
1998: H Matsushita; Ryuichi Morishita; Iwao Kida; Motokuni Aoki; Seiji Hayashi; Naruya Tomita; Kazuhiro Yamamoto; Atsushi Moriguchi; A Noda; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Inhibition of growth of human vascular smooth muscle cells by overexpression of p21 gene through induction of apoptosis.
Hypertension 1998;31(1 Pt 2):493-8.
1997: Yukihiko Saeki; Norinao Matsumoto; Y Nakano; Masahide Mori; K Awai; Yasufumi Kaneda
Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): reciprocal effect of cationic lipid for in vitro and in vivo gene transfer.
Human gene therapy 1997;8(17):2133-41.
1997: Yoshiki Sawa; Ryuichi Morishita; K Suzuki; Koji Kagisaki; Yasufumi Kaneda; Kazuhisa Maeda; K Kadoba; Hikaru Matsuda
A novel strategy for myocardial protection using in vivo transfection of cis element 'decoy' against NFkappaB binding site: evidence for a role of NFkappaB in ischemia-reperfusion injury.
Circulation 1997;96(9 Suppl):II-280-4; discussion II-285.
1997: Yasufumi Kaneda; Yoko Yamamoto; Shin-ichi Tsunoda; Haruhiko Kamada; Yasuo Tsutsumi; Toshio Hirano; Tadanori Mayumi
Bioconjugation of tumor necrosis factor-alpha with the copolymer of divinyl ether and maleic anhydride increasing its antitumor potency.
Biochemical and biophysical research communications 1997;239(1):160-5.
1997: E Mabuchi; Kiyonori Shimizu; Y Miyao; Yasufumi Kaneda; Haruhiko Kishima; M Tamura; Kazuhiro Ikenaka; Takao Hayakawa
Gene delivery by HVJ-liposome in the experimental gene therapy of murine glioma.
Gene therapy 1997;4(8):768-72.
1997: Yasufumi Kaneda; Y Yamamoto; Naoki Okada; Y Tsutsuml; Shinsaku Nakagawa; M Kakiuch; Mitsuko Maeda; Koichi Kawasaki; Tadanori Mayumi
Antimetastatic effect of synthetic Glu-Ile-Leu-Asp-Val peptide derivatives containing D-amino acids.
Anti-cancer drugs 1997;8(7):702-7.
1997: Ryuichi Morishita; T Sugimoto; Motokuni Aoki; Iwao Kida; Naruya Tomita; Atsushi Moriguchi; K Maeda; Yoshiki Sawa; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction.
Nature medicine 1997;3(8):894-9.
1997: Yasufumi Kaneda
[Liposome-mediated gene delivery].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1806-13.
1997: Shin'ichi Takeda; Yoshiki Sawa; Masato Minami; Yasufumi Kaneda; Y Fujii; Ryota Shirakura; Masashi Yanagisawa; Hikaru Matsuda
Experimental bronchiolitis obliterans induced by in vivo HVJ-liposome-mediated endothelin-1 gene transfer.
The Annals of thoracic surgery 1997;63(6):1562-7.
1997: Tetsuya Tomita; Hideo Hashimoto; Naruya Tomita; Ryuichi Morishita; S B Lee; K Hayashida; Norimasa Nakamura; Kazuo Yonenobu; Yasufumi Kaneda; Takahiro Ochi
In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes.
Arthritis and rheumatism 1997;40(5):901-6.
1997: Yasufumi Kaneda; Ryuichi Morishita; Victor J Dzau
Prevention of restenosis by gene therapy.
Annals of the New York Academy of Sciences 1997;811():299-308; discussion 308-10.
1997: Motokuni Aoki; Ryuichi Morishita; A Muraishi; Atsushi Moriguchi; T Sugimoto; K Maeda; Victor J Dzau; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Efficient in vivo gene transfer into the heart in the rat myocardial infarction model using the HVJ (Hemagglutinating Virus of Japan)--liposome method.
Journal of molecular and cellular cardiology 1997;29(3):949-59.
1997: Enyu Imai; Yoshitaka Isaka; Yoshitaka Akagi; Yasufumi Kaneda
Gene transfer into the glomerulus by the hemagglutinating virus of Japan-liposome method.
Experimental nephrology 1997;5(2):112-7.
1997: Yoshiki Sawa; K Kadoba; K Suzuki; HZ Bai; Yasufumi Kaneda; Ryota Shirakura; Hikaru Matsuda
Efficient gene transfer method into the whole heart through the coronary artery with hemagglutinating virus of Japan liposome.
The Journal of thoracic and cardiovascular surgery 1997;113(3):512-8; discussion 518-9.
1997: Motokuni Aoki; Ryuichi Morishita; Jitsuo Higaki; Atsushi Moriguchi; Iwao Kida; Seiji Hayashi; H Matsushita; Yasufumi Kaneda; Toshio Ogihara
In vivo transfer efficiency of antisense oligonucleotides into the myocardium using HVJ-liposome method.
Biochemical and biophysical research communications 1997;231(3):540-5.
1997: Yasufumi Kaneda; Ryuichi Morishita
[Development of in vivo gene transfer methods towards future gene therapy].
Rinsho byori. The Japanese journal of clinical pathology 1997;45(2):99-105.
1997: Motokuni Aoki; Ryuichi Morishita; Jitsuo Higaki; Atsushi Moriguchi; Seiji Hayashi; H Matsushita; Iwao Kida; Naruya Tomita; Yoshiki Sawa; Yasufumi Kaneda; Toshio Ogihara
Survival of grafts of genetically modified cardiac myocytes transfected with FITC-labeled oligodeoxynucleotides and the beta-galactosidase gene in the noninfarcted area, but not the myocardial infarcted area.
Gene therapy 1997;4(2):120-7.
1997: Yasuo Tsutsumi; Shin-ichi Tsunoda; Haruhiko Kamada; Tetsuya Kihira; Yasufumi Kaneda; Yoshiyuki Ohsugi; Tadanori Mayumi
PEGylation of interleukin-6 effectively increases its thrombopoietic potency.
Thrombosis and haemostasis 1997;77(1):168-73.
1996: M Sato; Kayoko Kinoshita; Yasufumi Kaneda; Yukihiko Saeki; A Iwamatsu; K Tanaka
Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40).
Biochemical and biophysical research communications 1996;229(3):896-901.
1996: Yasufumi Kaneda
[Structure and function of higher eukaryote chromosome].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2219-29.
1996: K Yamada; Atsushi Moriguchi; Ryuichi Morishita; Motokuni Aoki; Y Nakamura; Hiroshi Mikami; T Oshima; M Ninomiya; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Efficient oligonucleotide delivery using the HVJ-liposome method in the central nervous system.
The American journal of physiology 1996;271(5 Pt 2):R1212-20.
1996: Yasuo Tsutsumi; Shin-ichi Tsunoda; Yasufumi Kaneda; Haruhiko Kamada; Tetsuya Kihira; Shinsaku Nakagawa; Yoko Yamamoto; Y Horisawa; Tadanori Mayumi
In vivo anti-tumor efficacy of polyethylene glycol-modified tumor necrosis factor-alpha against tumor necrosis factor-resistant tumors.
Japanese journal of cancer research : Gann 1996;87(10):1078-85.
1996: Yasufumi Kaneda
[Development of non-viral gene delivery system and its applications].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(10):2829-38.
1996: Seiji Hayashi; Ryuichi Morishita; Motokuni Aoki; Atsushi Moriguchi; Iwao Kida; M Nakajima; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid.
Gene therapy 1996;3(10):878-85.
1996: Yasuo Tsutsumi; Shin-ichi Tsunoda; Haruhiko Kamada; Tetsuya Kihira; Shinsaku Nakagawa; Yasufumi Kaneda; T Kanamori; Tadanori Mayumi
Molecular design of hybrid tumour necrosis factor-alpha. II: The molecular size of polyethylene glycol-modified tumour necrosis factor-alpha affects its anti-tumour potency.
British journal of cancer 1996;74(7):1090-5.
1996: Yasuo Tsutsumi; Tetsuya Kihira; Shin-ichi Tsunoda; Haruhiko Kamada; Shinsaku Nakagawa; Yasufumi Kaneda; T Kanamori; Tadanori Mayumi
Molecular design of hybrid tumor necrosis factor-alpha III: polyethylene glycol-modified tumor necrosis factor-alpha has markedly enhanced antitumor potency due to longer plasma half-life and higher tumor accumulation.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1006-11.
1996: Naoki Okada; Yasufumi Kaneda; H Miyamoto; Yoko Yamamoto; H Mizuguchi; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Selective enhancement by tumor necrosis factor-alpha of vascular permeability of new blood vessels induced with agarose hydrogel-entrapped Meth-A fibrosarcoma cells.
Japanese journal of cancer research : Gann 1996;87(8):831-6.
1996: N Tomita; Ryuichi Morishita; Jitsuo Higaki; S Tomita; Motokuni Aoki; Yasufumi Kaneda; Toshio Ogihara
Sustained transgene expression by transfection of renin gene into liver of neonates.
Biochemical and biophysical research communications 1996;224(1):43-9.
1996: Yoshitaka Akagi; Yoshitaka Isaka; M Arai; T Kaneko; Masaru Takenaka; Toshiki Moriyama; Yasufumi Kaneda; A Ando; Yoshimasa Orita; T Kamada; N Ueda; Enyu Imai
Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis.
Kidney international 1996;50(1):148-55.
1996: Itaru Yanagihara; Koji Inui; George Dickson; G Turner; T Piper; Yasufumi Kaneda; Shintaro Okada
Expression of full-length human dystrophin cDNA in mdx mouse muscle by HVJ-liposome injection.
Gene therapy 1996;3(6):549-53.
1996: N Tomita; Ryuichi Morishita; Jitsuo Higaki; S Tomita; Motokuni Aoki; Toshio Ogihara; Yasufumi Kaneda
In vivo gene transfer of insulin gene into neonatal rats by the HVJ-liposome method resulted in sustained transgene expression.
Gene therapy 1996;3(6):477-82.
1996: Seiji Hayashi; Ryuichi Morishita; Jitsuo Higaki; Motokuni Aoki; Atsushi Moriguchi; Iwao Kida; S Yoshiki; K Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Autocrine-paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells.
Biochemical and biophysical research communications 1996;220(3):539-45.
1996: Ryuichi Morishita; Jitsuo Higaki; N Tomita; Motokuni Aoki; Atsushi Moriguchi; K Tamura; K Murakami; Yasufumi Kaneda; Toshio Ogihara
Role of transcriptional cis-elements, angiotensinogen gene-activating elements, of angiotensinogen gene in blood pressure regulation.
Hypertension 1996;27(3 Pt 2):502-7.
1996: Ryuichi Morishita; Jitsuo Higaki; M Aoki; S Hayashi; Iwao Kida; Yasufumi Kaneda; Toshio Ogihara
Novel strategy of gene therapy in cardiovascular disease with HVJ-liposome method.
Contributions to nephrology 1996;118():254-64.
1996: Enyu Imai; Yoshitaka Isaka; Y Akagi; M Arai; T Moriyama; M Takenaka; T Kaneko; M Horio; A Ando; Yoshimasa Orita; Yasufumi Kaneda; N Ueda; T Kamada
Application of antisense oligodeoxynucleotides (ODNs) for the intervention of kidney disease. Antisense ODNs for transforming growth factor-beta-suppressed glomerulosclerosis in experimental glomerulonephritis.
Contributions to nephrology 1996;118():86-93.
1996: Norimasa Nakamura; Shuji Horibe; Norinao Matsumoto; Tetsuya Tomita; T Natsuume; Yasufumi Kaneda; Konsei Shino; Takahiro Ochi
Transient introduction of a foreign gene into healing rat patellar ligament.
The Journal of clinical investigation 1996;97(1):226-31.
1995: M Wataya-Kaneda; K Hashimoto; Kunihiko Yoshikawa; Yasufumi Kaneda
The loss of 40-kDa chromosomal protein in tuberous sclerosis lesions.
Biochemical and biophysical research communications 1995;217(2):599-607.
1995: N Tomita; Ryuichi Morishita; Jitsuo Higaki; S Tomita; Motokuni Aoki; Yasufumi Kaneda; Toshio Ogihara
Effect of angiotensinogen on blood pressure regulation in normotensive rats: application of a loss of function approach.
Journal of hypertension 1995;13(12 Pt 2):1767-74.
1995: Shuntaro Hara; Ryuichi Morishita; Yoshinori Tone; Chieko Yokoyama; H Inoue; Yasufumi Kaneda; Toshio Ogihara; Tadashi Tanabe
Overexpression of prostacyclin synthase inhibits growth of vascular smooth muscle cells.
Biochemical and biophysical research communications 1995;216(3):862-7.
1995: Yoshiki Sawa; K Suzuki; HZ Bai; Ryota Shirakura; Ryuichi Morishita; Yasufumi Kaneda; H Matsuda
Efficiency of in vivo gene transfection into transplanted rat heart by coronary infusion of HVJ liposome.
Circulation 1995;92(9 Suppl):II479-82.
1995: Yasufumi Kaneda
[Induction of hepatitis in rats injected with HBV-DNA using HVJ-liposome].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 2):104-10.
1995: Yasufumi Kaneda; Ryuichi Morishita; N Tomita
Increased expression of DNA cointroduced with nuclear protein in adult rat liver.
Journal of molecular medicine (Berlin, Germany) 1995;73(6):289-97.
1995: M Arai; A Wada; Yoshitaka Isaka; Yoshitaka Akagi; T Sugiura; M Miyazaki; Toshiki Moriyama; Yasufumi Kaneda; K Naruse; M Naruse
In vivo transfection of genes for renin and angiotensinogen into the glomerular cells induced phenotypic change of the mesangial cells and glomerular sclerosis.
Biochemical and biophysical research communications 1995;206(2):525-32.
1995: Yasufumi Kaneda; S Yamamoto; Tetsuya Kihira; Yasuo Tsutsumi; Shinsaku Nakagawa; M Miyake; K Kawasaki; Tadanori Mayumi
Synthetic cell-adhesive laminin peptide YIGSR conjugated with polyethylene glycol has improved antimetastatic activity due to a longer half-life in blood.
Invasion & metastasis 1995;15(3-4):156-62.
1994: S Yamamoto; Yasufumi Kaneda; N Okada; Shinsaku Nakagawa; K Kubo; S Inoue; M Maeda; Y Yamashiro; K Kawasaki; Tadanori Mayumi
Antimetastatic effects of synthetic peptides containing the core sequence of the type III connecting segment domain (IIICS) of fibronectin.
Anti-cancer drugs 1994;5(4):424-8.
1994: Enyu Imai; Yoshitaka Isaka; Y Fujiwara; Yasufumi Kaneda; T Kamada; N Ueda
Introduction of a foreign gene into the kidney in vivo: development of glomerulosclerosis by the transfection of genes for PDGF and TGF-beta.
Contributions to nephrology 1994;107():205-15.
1994: N Tomita; Jitsuo Higaki; Toshio Ogihara; T Kondo; Yasufumi Kaneda
A novel gene-transfer technique mediated by HVJ (Sendai virus), nuclear protein, and liposomes.
Cancer detection and prevention 1994;18(6):485-91.
1993: Yoshitaka Isaka; Y Fujiwara; N Ueda; Yasufumi Kaneda; T Kamada; Enyu Imai
Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.
The Journal of clinical investigation 1993;92(6):2597-601.
1993: S Fujita; E Shin; Tadashi Nakamura; H Kurahashi; Yasufumi Kaneda; K Tanaka; T Mori; Shin-ichiro Takai; I Nishisho
Construction of radiation-reduced hybrids and their use in mapping of microclones from chromosome 10p11.2-q11.2.
The Japanese journal of human genetics 1993;38(4):361-70.
1993: N Tomita; Jitsuo Higaki; Yasufumi Kaneda; H Yu; Ryuichi Morishita; Hiroshi Mikami; Toshio Ogihara
Hypertensive rats produced by in vivo introduction of the human renin gene.
Circulation research 1993;73(5):898-905.
1993: Yasufumi Kaneda; K Kinoshita; M Sato; K Tanaka; Y Kaneda
The analysis of 40 kDa nuclear protein, p40, in interphase cells and mitotic cells.
Journal of cell science 1993;106 ( Pt 3)():741-8.
1993: Yasufumi Kaneda; K Kato; Mahito Nakanishi; T Uchida
Introduction of plasmid DNA and nuclear protein into cells by using erythrocyte ghosts, liposomes, and Sendai virus.
Methods in enzymology 1993;221():317-27.
1992: N Tomita; Jitsuo Higaki; Yasufumi Kaneda; Toshio Ogihara
[Direct in vivo gene introduction into rat kidney].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(12):2874-8.
1992: Yoshihiro Yoneda; T Semba; Yasufumi Kaneda; R L Noble; Y Matsuoka; T Kurihara; Y Okada; Naoko Imamoto
A long synthetic peptide containing a nuclear localization signal and its flanking sequences of SV40 T-antigen directs the transport of IgM into the nucleus efficiently.
Experimental cell research 1992;201(2):313-20.
1992: N Tomita; Jitsuo Higaki; Ryuichi Morishita; K Kato; Hiroshi Mikami; Yasufumi Kaneda; Toshio Ogihara
Direct in vivo gene introduction into rat kidney.
Biochemical and biophysical research communications 1992;186(1):129-34.
1991: K Kato; Yasufumi Kaneda; M Sakurai; Mahito Nakanishi; Y Okada
Direct injection of hepatitis B virus DNA into liver induced hepatitis in adult rats.
The Journal of biological chemistry 1991;266(33):22071-4.
1991: Akihiro Yoneda; Y Yoneda; Yasufumi Kaneda; H Hayes; T Uchida; Y Okada
Monoclonal antibodies specific for human chromosome 5 obtained with a monochromosomal hybrid can be used to sort out cells containing the chromosome with a FACS.
Chromosoma 1991;100(3):187-92.
1991: K Kato; Mahito Nakanishi; Yasufumi Kaneda; T Uchida; Y Okada
Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified liposome method.
The Journal of biological chemistry 1991;266(6):3361-4.
1989: Yasufumi Kaneda; K Iwai; T Uchida
Introduction and expression of the human insulin gene in adult rat liver.
The Journal of biological chemistry 1989;264(21):12126-9.
1989: Yasufumi Kaneda; K Iwai; T Uchida
Increased expression of DNA cointroduced with nuclear protein in adult rat liver.
Science (New York, N.Y.) 1989;243(4889):375-8.
1987: Yasufumi Kaneda; T Uchida; J Kim; M Ishiura; Y Okada
The improved efficient method for introducing macromolecules into cells using HVJ (Sendai virus) liposomes with gangliosides.
Experimental cell research 1987;173(1):56-69.
1987: H Hayes; Yasufumi Kaneda; T Uchida; Y Okada
Regional assignment of the gene for diphtheria toxin sensitivity using subchromosomal fragments in microcell hybrids.
Chromosoma 1987;96(1):26-32.