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Yasufumi Kaneda

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Procedures

Gene Therapy

Physiology

Chemicals & Drugs

Living Beings

Devices

Gene Transfer Techniques

Anatomy

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Co-Publications
Name
130
Morishita, Ryuichi
92
Ogihara, Toshio
53
Aoki, Motokuni
32
Higaki, Jitsuo
31
Tomita, Naruya
29
Nakagami, Hironori
28
Tamai, Katsuto
24
Sawa, Yoshiki
21
Matsuda, Hikaru
17
Moriguchi, Atsushi
17
Taniyama, Yoshiaki
15
Nakamura, Tadashi
14
Nakamura, Toshikazu
14
Mayumi, Tadanori
13
Hayashi, Seiji

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Publications

TOP 3
Tamai Katsuto; Kaneda Yasufumi; Uitto Jouni
Molecular therapies for heritable blistering diseases.
Nimura Keisuke; Ura Kiyoe; Shiratori Hidetaka; Ikawa Masato; Okabe Masaru; Schwartz Robert J; Kaneda Yasufumi
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
Mori Masaki; Nakagami Hironori; Koibuchi Nobutaka; Miura Koichi; Takami Yoichi; Koriyama Hiroshi; Hayashi Hiroki; Sabe Hisataka; Mochizuki Naoki; Morishita Ryuichi; Kaneda Yasufumi
Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis.

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All Publications

2009: Tamai Katsuto; Kaneda Yasufumi; Uitto Jouni
Molecular therapies for heritable blistering diseases.
Trends in molecular medicine 2009;15(7):285-92.
2009: Nimura Keisuke; Ura Kiyoe; Shiratori Hidetaka; Ikawa Masato; Okabe Masaru; Schwartz Robert J; Kaneda Yasufumi
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
Nature 2009;460(7252):287-91.
2009: Mori Masaki; Nakagami Hironori; Koibuchi Nobutaka; Miura Koichi; Takami Yoichi; Koriyama Hiroshi; Hayashi Hiroki; Sabe Hisataka; Mochizuki Naoki; Morishita Ryuichi; Kaneda Yasufumi
Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis.
Molecular biology of the cell 2009;20(13):3115-24.
2009: Kaneda Yasufumi
[Progress of human gene therapy]
Nippon rinsho. Japanese journal of clinical medicine 2009;67(6):1180-4.
2009: Hayashi Hiroki; Nakagami Hironori; Takami Yoichi; Koriyama Hiroshi; Mori Masaki; Tamai Katsuto; Sun Jianxin; Nagao Kaori; Morishita Ryuichi; Kaneda Yasufumi
FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):909-14.
2009: Kawaguchi Yoshifumi; Miyamoto Yasuhide; Inoue Takehiro; Kaneda Yasufumi
Efficient eradication of hormone-resistant human prostate cancers by inactivated Sendai virus particle.
International journal of cancer. Journal international du cancer 2009;124(10):2478-87.
2009: Nishikawa Tomoyuki; Nakagami Hironori; Maeda Akito; Morishita Ryuichi; Miyazaki Nobuhiko; Ogawa Toshihiro; Tabata Yasuhiko; Kikuchi Yasushi; Hayashi Hiroki; Tatsu Yoshiro; Yumoto Noboru; Tamai Katsuto; Tomono Kazunori; Kaneda Yasufumi
Development of a novel antimicrobial peptide, AG-30, with angiogenic properties.
Journal of cellular and molecular medicine 2009;13(3):535-46.
2008: Chino Takenao; Tamai Katsuto; Yamazaki Takehiko; Otsuru Satoru; Kikuchi Yasushi; Nimura Keisuke; Endo Masayuki; Nagai Miki; Uitto Jouni; Kitajima Yasuo; Kaneda Yasufumi
Bone marrow cell transfer into fetal circulation can ameliorate genetic skin diseases by providing fibroblasts to the skin and inducing immune tolerance.
The American journal of pathology 2008;173(3):803-14.
2008: Kikuchi Yasushi; Tamai Katsuto; Kaneda Yasufumi
Cutaneous gene delivery.
Journal of dermatological science 2008;50(2):87-98.
2008: Suzuki Hayato; Kurooka Masayuki; Hiroaki Yoko; Fujiyoshi Yoshinori; Kaneda Yasufumi
Sendai virus F glycoprotein induces IL-6 production in dendritic cells in a fusion-independent manner.
FEBS letters 2008;582(9):1325-9.
2008: Saito Y; Nakagami H; Kurooka M; Takami Y; Kikuchi Y; Hayashi H; Nishikawa T; Tamai K; Morishita R; Azuma N; Sasajima T; Kaneda Y
Cold shock domain protein A represses angiogenesis and lymphangiogenesis via inhibition of serum response element.
Oncogene 2008;27(13):1821-33.
2008: Kaneda Yasufumi
Applications of Hemagglutinating Virus of Japan in therapeutic delivery systems.
Expert opinion on drug delivery 2008;5(2):221-33.
2008: Saga Kotaro; Tamai Katsuto; Kawachi Masako; Shimbo Takashi; Fujita Hiroshi; Yamazaki Takehiko; Kaneda Yasufumi
Functional modification of Sendai virus by siRNA.
Journal of biotechnology 2008;133(3):386-94.
2008: Otsuru Satoru; Tamai Katsuto; Yamazaki Takehiko; Yoshikawa Hideki; Kaneda Yasufumi
Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway.
Stem cells (Dayton, Ohio) 2008;26(1):223-34.
2008: Fujihara Atsuko; Kurooka Masayuki; Miki Tsuneharu; Kaneda Yasufumi
Intratumoral injection of inactivated Sendai virus particles elicits strong antitumor activity by enhancing local CXCL10 expression and systemic NK cell activation.
Cancer immunology, immunotherapy : CII 2008;57(1):73-84.
2007: Nakagami Hironori; Kikuchi Yasushi; Katsuya Tomohiro; Morishita Ryuichi; Akasaka Hiroshi; Saitoh Shigeyuki; Rakugi Hiromi; Kaneda Yasufumi; Shimamoto Kazuaki; Ogihara Toshio
Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(12):1239-46.
2007: Shimbo Takashi; Kawachi Masako; Saga Kotaro; Fujita Hiroshi; Yamazaki Takehiko; Tamai Katsuto; Kaneda Yasufumi
Development of a transferrin receptor-targeting HVJ-E vector.
Biochemical and biophysical research communications 2007;364(3):423-8.
2007: Hayashi Hiroki; Nakagami Hironori; Takami Yoichi; Sato Naoyuki; Saito Yukihiro; Nishikawa Tomoyuki; Mori Masaki; Koriyama Hiroshi; Tamai Katsuto; Morishita Ryuichi; Kaneda Yasufumi
Involvement of gamma-secretase in postnatal angiogenesis.
Biochemical and biophysical research communications 2007;363(3):584-90.
2007: Miyake Takashi; Aoki Motokuni; Masaki Hisao; Kawasaki Tomio; Oishi Masako; Kataoka Kazusaburo; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
Regression of abdominal aortic aneurysms by simultaneous inhibition of nuclear factor kappaB and ets in a rabbit model.
Circulation research 2007;101(11):1175-84.
2007: Kawachi Masako; Tamai Katsuto; Saga Kotaro; Yamazaki Takehiko; Fujita Hiroshi; Shimbo Takashi; Kikuchi Yasushi; Nimura Keisuke; Nishifuji Koji; Amagai Masayuki; Uitto Jouni; Kaneda Yasufumi
Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin.
Human gene therapy 2007;18(10):881-94.
2007: Takami Yoichi; Nakagami Hironori; Morishita Ryuichi; Katsuya Tomohiro; Cui Tai-Xing; Ichikawa Tomonaga; Saito Yukihiro; Hayashi Hiroki; Kikuchi Yasushi; Nishikawa Tomoyuki; Baba Yoshichika; Yasuda Osamu; Rakugi Hiromi; Ogihara Toshio; Kaneda Yasufumi
Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(10):2184-90.
2007: Hayashi Masanori; Nimura Keisuke; Kashiwagi Katsunobu; Harada Taku; Takaoka Kunio; Kato Hiroyuki; Tamai Katsuto; Kaneda Yasufumi
Comparative roles of Twist-1 and Id1 in transcriptional regulation by BMP signaling.
Journal of cell science 2007;120(Pt 8):1350-7.
2007: Otsuru Satoru; Tamai Katsuto; Yamazaki Takehiko; Yoshikawa Hideki; Kaneda Yasufumi
Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice.
Biochemical and biophysical research communications 2007;354(2):453-8.
2007: Yasuoka Eri; Oshima Kazuo; Tamai Katsuto; Kubo Takeshi; Kaneda Yasufumi
Needleless intranasal administration of HVJ-E containing allergen attenuates experimental allergic rhinitis.
Journal of molecular medicine (Berlin, Germany) 2007;85(3):283-92.
2007: Kurooka Masayuki; Kaneda Yasufumi
Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
Cancer research 2007;67(1):227-36.
2007: Suvanasuthi Saroj; Tamai Katsuto; Kaneda Yasufumi
Rapid transport of plasmid DNA into the nucleolus via actin depolymerization using the HVJ envelope vector.
The journal of gene medicine 2007;9(1):55-62.
2007: Kawano Hirokazu; Komaba Shintarou; Kanamori Toshihide; Kaneda Yasufumi
A new therapy for highly effective tumor eradication using HVJ-E combined with chemotherapy.
BMC medicine 2007;5():28.
2006: Koike H; Ishida A; Shimamura M; Mizuno S; Nakamura T; Ogihara T; Kaneda Y; Morishita R
Prevention of onset of Parkinson's disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson's disease.
Gene therapy 2006;13(23):1639-44.
2006: Nimura Keisuke; Ishida Chisaki; Koriyama Hiroshi; Hata Kenichiro; Yamanaka Shinya; Li En; Ura Kiyoe; Kaneda Yasufumi
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(10):1225-37.
2006: Shiraya Suguru; Miwa Ken; Aoki Motokuni; Miyake Takashi; Oishi Masako; Kataoka Kazusaburo; Ohgi Shigetsugu; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
Hypertension accelerated experimental abdominal aortic aneurysm through upregulation of nuclear factor kappaB and Ets.
Hypertension 2006;48(4):628-36.
2006: Takeda Shin-ichi; Terazono Bungo; Mishima Fumihito; Nakagami Hironori; Nishijima Shigehiro; Kaneda Yasufumi
Novel drug delivery system by surface modified magnetic nanoparticles.
Journal of nanoscience and nanotechnology 2006;6(9-10):3269-76.
2006: Saito Yukihiro; Nakagami Hironori; Morishita Ryuichi; Takami Yoichi; Kikuchi Yasushi; Hayashi Hiroki; Nishikawa Tomoyuki; Tamai Katsuto; Azuma Nobuyoshi; Sasajima Tadahiro; Kaneda Yasufumi
Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis.
Circulation 2006;114(11):1177-84.
2006: Miyake Takashi; Aoki Motokuni; Shiraya Suguru; Tanemoto Kazuo; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model.
Journal of molecular and cellular cardiology 2006;41(3):431-40.
2006: Tomita Tetsuya; Kunugiza Yasuo; Tomita Naruya; Takano Hiroshi; Morishita Ryuichi; Kaneda Yasufumi; Yoshikawa Hideki
E2F decoy oligodeoxynucleotide ameliorates cartilage invasion by infiltrating synovium derived from rheumatoid arthritis.
International journal of molecular medicine 2006;18(2):257-65.
2006: Kunugiza Y; Tomita N; Taniyama Y; Tomita T; Osako M K; Tamai K; Tanabe T; Kaneda Y; Yoshikawa H; Morishita R
Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet.
Gene therapy 2006;13(15):1143-52.
2006: Shimizu H; Nakagami H; Tsukamoto I; Morita S; Kunugiza Y; Tomita T; Yoshikawa H; Kaneda Y; Ogihara T; Morishita R
NFkappaB decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts.
Gene therapy 2006;13(12):933-41.
2006: Koyama Shinsuke; Kimura Tadashi; Ogita Kazuhide; Nakamura Hitomi; Tabata Chisa; Md Abu Hadi Noor Ali Khan; Temma-Asano Kumiko; Shimoya Koichiro; Tsutsui Tateki; Koyama Masayasu; Kaneda Yasufumi; Murata Yuji
Simple and highly efficient method for transient in vivo gene transfer to mid-late pregnant mouse uterus.
Journal of reproductive immunology 2006;70(1-2):59-69.
2006: Nakamura Hitomi; Kimura Tadashi; Koyama Shinsuke; Ogita Kazuhide; Tsutsui Tateki; Shimoya Koichiro; Taniguchi Takeshi; Koyama Masayasu; Kaneda Yasufumi; Murata Yuji
Mouse model of human infertility: transient and local inhibition of endometrial STAT-3 activation results in implantation failure.
FEBS letters 2006;580(11):2717-22.
2006: Koibuchi Nobutaka; Taniyama Yoshiaki; Nagao Kaori; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
The effect of VEGF on blood vessels and blood cells during Xenopus development.
Biochemical and biophysical research communications 2006;344(1):339-45.
2006: Kaneda Yasufumi; Tabata Yasuhiko
Non-viral vectors for cancer therapy.
Cancer science 2006;97(5):348-54.
2006: Nakagami Hironori; Morishita Ryuichi; Maeda Kazuhisa; Kikuchi Yasushi; Ogihara Toshio; Kaneda Yasufumi
Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy.
Journal of atherosclerosis and thrombosis 2006;13(2):77-81.
2006: Nakagami Hironori; Tomita Naruya; Kaneda Yasufumi; Ogihara Toshio; Morishita Ryuichi
Anti-oxidant gene therapy by NF kappa B decoy oligodeoxynucleotide.
Current pharmaceutical biotechnology 2006;7(2):95-100.
2006: Mima Hidetoshi; Yamamoto Seiji; Ito Makoto; Tomoshige Ryuji; Tabata Yasuhiko; Tamai Katsuto; Kaneda Yasufumi
Targeted chemotherapy against intraperitoneally disseminated colon carcinoma using a cationized gelatin-conjugated HVJ envelope vector.
Molecular cancer therapeutics 2006;5(4):1021-8.
2006: Seki Yosuke; Yamamoto Hirofumi; Ngan Chew Yee; Yasui Masayoshi; Tomita Naruya; Kitani Kotaro; Takemasa Ichiro; Ikeda Masataka; Sekimoto Mitsugu; Matsuura Nariaki; Albanese Chris; Kaneda Yasufumi; Pestell Richard G; Monden Morito
Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway.
Molecular cancer therapeutics 2006;5(4):985-94.
2006: Nishikawa Tomoyuki; Nakagami Hironori; Matsuki Atsushi; Maeda Akito; Yo Chiah Yian; Harada Taku; Morishita Ryuichi; Tamai Katsuto; Kaneda Yasufumi
Development of high-throughput functional screening of therapeutic genes, using a hemagglutinating virus of Japan envelope vector.
Human gene therapy 2006;17(4):470-5.
2006: Shimamura Munehisa; Sato Naoyuki; Waguri Satoshi; Uchiyama Yasuo; Hayashi Takuya; Iida Hidehiro; Nakamura Toshikazu; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction.
Hypertension 2006;47(4):742-51.
2006: Miyake T; Aoki M; Nakashima H; Kawasaki T; Oishi M; Kataoka K; Tanemoto K; Ogihara T; Kaneda Y; Morishita R
Prevention of abdominal aortic aneurysms by simultaneous inhibition of NFkappaB and ets using chimeric decoy oligonucleotides in a rabbit model.
Gene therapy 2006;13(8):695-704.
2006: Shimamura Munehisa; Sato Naoyuki; Yoshimura Shinichi; Kaneda Yasufumi; Morishita Ryuichi
HVJ-based non-viral gene transfer method: successful gene therapy using HGF and VEGF genes in experimental ischemia.
Frontiers in bioscience : a journal and virtual library 2006;11():753-9.
2005: Tamai Katsuto; Kaneda Yasufumi; Nakamura Hiroshige; Aoki Motohiro; Morishita Ryuichi; Hashimoto Koji; Morita Akimichi; Katayama Ichiro; Hanada Katsumi
[NFkappaB decoy DNA for treatment of atopic dermatitis]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():659-63.
2005: Nkagami Hironori; Kaneda Yasufumi; Morishita Ryuichi
[Future view of gene therapy in cardiovascular field]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():577-81.
2005: Kaneda Yasufumi
[Strategies for gene therapy]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():486-90.
2005: Kaneda Yasufumi
[Current status and future prospective of gene therapy]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():469-74.
2005: Nakagami Hironori; Maeda Kazuhisa; Morishita Ryuichi; Iguchi Sota; Nishikawa Tomoyuki; Takami Yoichi; Kikuchi Yasushi; Saito Yukihiro; Tamai Katsuto; Ogihara Toshio; Kaneda Yasufumi
Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2542-7.
2005: Shimamura Munehisa; Sato Naoyuki; Taniyama Yoshiaki; Kurinami Hitomi; Tanaka Hiroyuki; Takami Toshihiro; Ogihara Toshio; Tohyama Masaya; Kaneda Yasufumi; Morishita Ryuichi
Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles.
The journal of gene medicine 2005;7(11):1468-74.
2005: Kimura Tadashi; Nakamura Hitomi; Koyama Shinsuke; Ogita Kazuhide; Tabata Chisa; Tsutsui Tateki; Shimoya Koichiro; Koyama Masayasu; Kaneda Yasufumi; Murata Yuji
In vivo gene transfer into the mouse uterus: a powerful tool for investigating implantation physiology.
Journal of reproductive immunology 2005;67(1-2):13-20.
2005: Shirakawa Yukitoshi; Sawa Yoshiki; Takewa Yoshiaki; Tatsumi Eisuke; Kaneda Yasufumi; Taenaka Yoshiyuki; Matsuda Hikaru
Gene transfection with human hepatocyte growth factor complementary DNA plasmids attenuates cardiac remodeling after acute myocardial infarction in goat hearts implanted with ventricular assist devices.
The Journal of thoracic and cardiovascular surgery 2005;130(3):624-32.
2005: Ito Makoto; Yamamoto Seiji; Nimura Keisuke; Hiraoka Kazuya; Tamai Katsuto; Kaneda Yasufumi
Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin.
The journal of gene medicine 2005;7(8):1044-52.
2005: Miwa K; Nakashima H; Aoki M; Miyake T; Kawasaki T; Iwai M; Oishi M; Kataoka K; Ohgi S; Ogihara T; Kaneda Y; Morishita R
Inhibition of ets, an essential transcription factor for angiogenesis, to prevent the development of abdominal aortic aneurysm in a rat model.
Gene therapy 2005;12(14):1109-18.
2005: Mima Hidetoshi; Tomoshige Ryuji; Kanamori Toshihide; Tabata Yasuhiko; Yamamoto Seiji; Ito Susumu; Tamai Katsuto; Kaneda Yasufumi
Biocompatible polymer enhances the in vitro and in vivo transfection efficiency of HVJ envelope vector.
The journal of gene medicine 2005;7(7):888-97.
2005: Shigemura Norihisa; Sawa Yoshiki; Mizuno Shinya; Ono Masamichi; Minami Masato; Okumura Meinoshin; Nakamura Toshikazu; Kaneda Yasufumi; Matsuda Hikaru
Induction of compensatory lung growth in pulmonary emphysema improves surgical outcomes in rats.
American journal of respiratory and critical care medicine 2005;171(11):1237-45.
2005: Nakagami Hironori; Kaneda Yasufumi; Ogihara Toshio; Morishita Ryuichi
Hepatocyte growth factor as potential cardiovascular therapy.
Expert review of cardiovascular therapy 2005;3(3):513-9.
2005: Ono Masamichi; Sawa Yoshiki; Miyamoto Yuji; Fukushima Norihide; Ichikawa Hajime; Ishizaka Toru; Kaneda Yasufumi; Matsuda Hikaru
The effect of gene transfer with hepatocyte growth factor for pulmonary vascular hypoplasia in neonatal porcine model.
The Journal of thoracic and cardiovascular surgery 2005;129(4):740-5.
2005: Saeki Hideaki; Ohsumi Keita; Aihara Hitoshi; Ito Takashi; Hirose Susumu; Ura Kiyoe; Kaneda Yasufumi
Linker histone variants control chromatin dynamics during early embryogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(16):5697-702.
2005: Shigemura Norihisa; Sawa Yoshiki; Mizuno Shinya; Ono Masamichi; Ohta Mitsunori; Nakamura Toshikazu; Kaneda Yasufumi; Matsuda Hikaru
Amelioration of pulmonary emphysema by in vivo gene transfection with hepatocyte growth factor in rats.
Circulation 2005;111(11):1407-14.
2005: Nakagami Hironori; Kaneda Yasufumi; Ogihara Toshio; Morishita Ryuichi
Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis.
Current diabetes reviews 2005;1(1):59-63.
2005: Kaneda Yasufumi; Yamamoto Seiji; Nakajima Toshihiro
Development of HVJ envelope vector and its application to gene therapy.
Advances in genetics 2005;53():307-32.
2004: Tomita Naruya; Azuma Haruhito; Kaneda Yasufumi; Ogihara Toshio; Morishita Ryuichi
Application of decoy oligodeoxynucleotides-based approach to renal diseases.
Current drug targets 2004;5(8):717-33.
2004: Hiraoka Kazuya; Yamamoto Seiji; Otsuru Satoru; Nakai Seiji; Tamai Katsuto; Morishita Ryuichi; Ogihara Toshio; Kaneda Yasufumi
Enhanced tumor-specific long-term immunity of hemagglutinating [correction of hemaggluttinating] virus of Japan-mediated dendritic cell-tumor fused cell vaccination by coadministration with CpG oligodeoxynucleotides.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4297-307.
2004: Shimamura M; Sato N; Taniyama Y; Yamamoto S; Endoh M; Kurinami H; Aoki M; Ogihara T; Kaneda Y; Morishita R
Development of efficient plasmid DNA transfer into adult rat central nervous system using microbubble-enhanced ultrasound.
Gene therapy 2004;11(20):1532-9.
2004: Nakamura Hitomi; Kimura Tadashi; Ogita Kazuhide; Koyama Shinsuke; Tsujie Tomoko; Tsutsui Tateki; Shimoya Koichiro; Koyama Masayasu; Kaneda Yasufumi; Murata Yuji
Alteration of the timing of implantation by in vivo gene transfer: delay of implantation by suppression of nuclear factor kappaB activity and partial rescue by leukemia inhibitory factor.
Biochemical and biophysical research communications 2004;321(4):886-92.
2004: Morishita Ryuichi; Aoki Motokuni; Hashiya Naotaka; Makino Hirofumi; Yamasaki Keita; Azuma Junya; Sawa Yoshiki; Matsuda Hikaru; Kaneda Yasufumi; Ogihara Toshio
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease.
Hypertension 2004;44(2):203-9.
2004: Hashiya Naotaka; Jo Nobuo; Aoki Motokuni; Matsumoto Kunio; Nakamura Toshikazu; Sato Yasufumi; Ogata Nahoko; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
In vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade.
Circulation 2004;109(24):3035-41.
2004: Nakagami Hironori; Morishita Ryuichi; Nishikawa Tomoyuki; Shimizu Hideo; Iguchi Sota; Matsumoto Kunio; Nakamura Toshikazu; Kaneda Yasufumi; Ogihara Toshio
Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(5):359-65.
2004: Masuda Keita; Yamamoto Seiji; Endoh Masayuki; Kaneda Yasufumi
Transposon-independent increase of transcription by the Sleeping Beauty transposase.
Biochemical and biophysical research communications 2004;317(3):796-800.
2004: Tomita Naruya; Kim John Y S; Gibbons Gary H; Zhang Lunan; Kaneda Yasufumi; Stahl Rolf A K; Ogborn Malcom; Venderville Benoit; Morishita Ryuichi; Baran Dana; Dzau Victro J
Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis.
International journal of molecular medicine 2004;13(5):629-36.
2004: Koibuchi Nobutaka; Kaneda Yasufumi; Taniyama Yoshiaki; Matsumoto Kunio; Nakamura Toshikazu; Ogihara Toshio; Morishita Ryuichi
Essential role of HGF (hepatocyte growth factor) in blood formation in Xenopus.
Blood 2004;103(9):3320-5.
2004: Morishita Ryuichi; Tomita Naruya; Kaneda Yasufumi; Ogihara Toshio
Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides.
Current opinion in pharmacology 2004;4(2):139-46.
2004: Matsuki Atsushi; Yamamoto Seiji; Nakagami Hironori; Aoki Motokuni; Tamai Katsuto; Matsumoto Kunio; Nakamura Toshikazu; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice.
Biochemical and biophysical research communications 2004;315(1):59-65.
2004: Asano Yoshihiro; Takashima Seiji; Asakura Masanori; Shintani Yasunori; Liao Yulin; Minamino Tetsuo; Asanuma Hiroshi; Sanada Shoji; Kim Jiyoong; Ogai Akiko; Fukushima Tomi; Oikawa Yumiko; Okazaki Yasushi; Kaneda Yasufumi; Sato Manabu; Miyazaki Jun-ichi; Kitamura Soichiro; Tomoike Hitonobu; Kitakaze Masafumi; Hori Masatsugu
Lamr1 functional retroposon causes right ventricular dysplasia in mice.
Nature genetics 2004;36(2):123-30.
2004: Taniyama Yoshiaki; Tomita Naruya; Endoh Seiji; Kaneda Yasufumi; Ogihara Toshio; Morishita Ryuichi
[Gene transfer with ultrasound and microbubbles (optison) as a potential treatment for cardiovascular diseases]
Nippon Ronen Igakkai zasshi. Japanese journal of geriatrics 2004;41(1):51-4.
2004: Shimamura Munehisa; Sato Naoyuki; Oshima Kazuo; Aoki Motokuni; Kurinami Hitomi; Waguri Satoshi; Uchiyama Yasuo; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model.
Circulation 2004;109(3):424-31.
2004: Nakashima Hideki; Aoki Motokuni; Miyake Takashi; Kawasaki Tomio; Iwai Masahiro; Jo Nobuo; Oishi Masako; Kataoka Kazusaburo; Ohgi Shigetsugu; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
Inhibition of experimental abdominal aortic aneurysm in the rat by use of decoy oligodeoxynucleotides suppressing activity of nuclear factor kappaB and ets transcription factors.
Circulation 2004;109(1):132-8.
2004: Oshima Kazuo; Shimamura Munehisa; Mizuno Shinya; Tamai Katsuto; Doi Katsumi; Morishita Ryuichi; Nakamura Toshikazu; Kubo Takeshi; Kaneda Yasufumi
Intrathecal injection of HVJ-E containing HGF gene to cerebrospinal fluid can prevent and ameliorate hearing impairment in rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):212-4.
2003: Yamazaki Satoru; Iwamoto Ryo; Saeki Kazuko; Asakura Masanori; Takashima Seiji; Yamazaki Ayano; Kimura Rina; Mizushima Hiroto; Moribe Hiroki; Higashiyama Shigeki; Endoh Masayuki; Kaneda Yasufumi; Takagi Satoshi; Itami Satoshi; Takeda Naoki; Yamada Gen; Mekada Eisuke
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities.
The Journal of cell biology 2003;163(3):469-75.
2003: Kaneda Yasufumi
New vector innovation for drug delivery: development of fusigenic non-viral particles.
Current drug targets 2003;4(8):599-602.
2003: Namba Tsunetatsu; Koike Hiromi; Murakami Kazushi; Aoki Motokuni; Makino Hirofumi; Hashiya Naotaka; Ogihara Toshio; Kaneda Yasufumi; Kohno Masakazu; Morishita Ryuichi
Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model.
Circulation 2003;108(18):2250-7.
2003: Hiraoka Kazuya; Koike Hiromi; Yamamoto Seiji; Tomita Naruya; Yokoyama Chieko; Tanabe Tadashi; Aikou Takashi; Ogihara Toshio; Kaneda Yasufumi; Morishita Ryuichi
Enhanced therapeutic angiogenesis by cotransfection of prostacyclin synthase gene or optimization of intramuscular injection of naked plasmid DNA.
Circulation 2003;108(21):2689-96.
2003: Nakamura Hitomi; Kimura Tadashi; Ikegami Hiroyuki; Ogita Kazuhide; Koyama Shinsuke; Shimoya Koichiro; Tsujie Tomoko; Koyama Masayasu; Kaneda Yasufumi; Murata Yuji
Highly efficient and minimally invasive in-vivo gene transfer to the mouse uterus using haemagglutinating virus of Japan (HVJ) envelope vector.
Molecular human reproduction 2003;9(10):603-9.
2003: Hiraoka Kazuya; Kaneda Yasufumi
[Gene therapy for colorectal cancer in clinical trials]
Nippon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():522-5.
2003: Taniguchi Kazunori; Umeshita Koji; Sakon Masato; Miyoshi Hideyuki; Tokunaga Masaru; Ariyoshi Hideo; Yamano Tomoki; Kaneda Yasufumi; Monden Morito
Suppression of oxidative stress-induced hepatocyte injury by calpain antisense.
The Journal of surgical research 2003;111(1):23-7.
2003: Ishida Chisaki; Ura Kiyoe; Hirao Akiko; Sasaki Hiroyuki; Toyoda Atsushi; Sakaki Yoshiyuki; Niwa Hitoshi; Li En; Kaneda Yasufumi
Genomic organization and promoter analysis of the Dnmt3b gene.
Gene 2003;310():151-9.
2003: Tomita Naruya; Azuma Haruhito; Kaneda Yasufumi; Ogihara Toshio; Morishita Ryuichi
Gene therapy with transcription factor decoy oligonucleotides as a potential treatment for cardiovascular diseases.
Current drug targets 2003;4(4):339-46.
2003: Kaneda Yasufumi; Tamai Katsuto
Current status and future prospects of gene therapy technologies toward the treatment of intractable skin diseases.
Archives of dermatological research 2003;295 Suppl 1():S63-6.
2003: Koike Hiromi; Morishita Ryuichi; Iguchi Sohta; Aoki Motokuni; Matsumoto Kunio; Nakamura Toshikazu; Yokoyama Chieko; Tanabe Tadashi; Ogihara Toshio; Kaneda Yasufumi
Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):779-81.
2003: Tomita Naruya; Morishita Ryuichi; Taniyama Yoshiaki; Koike Hiromi; Aoki Motokuni; Shimizu Hideo; Matsumoto Kunio; Nakamura Toshikazu; Kaneda Yasufumi; Ogihara Toshio
Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1.
Circulation 2003;107(10):1411-7.
2003: Yamamoto Seiji; Yamano Tomoki; Tanaka Maki; Hoon Dave S B; Takao Sonshin; Morishita Ryuichi; Aikou Takashi; Kaneda Yasufumi
A novel combination of suicide gene therapy and histone deacetylase inhibitor for treatment of malignant melanoma.
Cancer gene therapy 2003;10(3):179-86.
2003: Yamasaki K; Asai T; Shimizu M; Aoki M; Hashiya N; Sakonjo H; Makino H; Kaneda Y; Ogihara T; Morishita R
Inhibition of NFkappaB activation using cis-element 'decoy' of NFkappaB binding site reduces neointimal formation in porcine balloon-injured coronary artery model.
Gene therapy 2003;10(4):356-64.
2003: Saitoh Youichi; Kato Amami; Hagihara Yasushi; Kaneda Yasufumi; Yoshimine Toshiki
Gene therapy for ischemic brain diseases.
Current gene therapy 2003;3(1):49-58.
2003: Nakabayashi M; Morishita R; Nakagami H; Kuba K; Matsumoto K; Nakamura T; Tano Y; Kaneda Y
HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model.
Diabetologia 2003;46(1):115-23.
2003: Shimamura Munehisa; Morishita Ryuichi; Endoh Masayuki; Oshima Kazuo; Aoki Motokuni; Waguri Satoshi; Uchiyama Yasuo; Kaneda Yasufumi
HVJ-envelope vector for gene transfer into central nervous system.
Biochemical and biophysical research communications 2003;300(2):464-71.
2003: Kaneda Yasufumi; Yamamoto Seiji; Hiraoka Kazuya
The hemagglutinating virus of Japan-liposome method for gene delivery.
Methods in enzymology 2003;373():482-93.
2003: Morishita Ryuichi; Kaneda Yasufumi; Ogihara Toshio
Therapeutic potential of oligonucleotide-based therapy in cardiovascular disease.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2003;17(6):383-9.
2002: Ono Masamichi; Sawa Yoshiki; Matsumoto Kunio; Nakamura Toshikazu; Kaneda Yasufumi; Matsuda Hikaru
In vivo gene transfection with hepatocyte growth factor via the pulmonary artery induces angiogenesis in the rat lung.
Circulation 2002;106(12 Suppl 1):I264-9.
2002: Tomita Naruya; Morishita Ryuichi; Yamamoto Kei; Higaki Jitsuo; Dzau Victor J; Ogihara Toshio; Kaneda Yasufumi
Targeted gene therapy for rat glomerulonephritis using HVJ-immunoliposomes.
The journal of gene medicine 2002;4(5):527-35.
2002: Nakamura H; Aoki M; Tamai K; Oishi M; Ogihara T; Kaneda Y; Morishita R
Prevention and regression of atopic dermatitis by ointment containing NF-kB decoy oligodeoxynucleotides in NC/Nga atopic mouse model.
Gene therapy 2002;9(18):1221-9.
2002: Kaneda Yasufumi; Nakajima Toshihiro; Nishikawa Tomoyuki; Yamamoto Seiji; Ikegami Hiroyuki; Suzuki Naho; Nakamura Hitomi; Morishita Ryuichi; Kotani Hitoshi
Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):219-26.
2002: Nakagami Hironori; Morishita Ryuichi; Yamamoto Kei; Taniyama Yoshiaki; Aoki Motokuni; Yamasaki Keita; Matsumoto Kunio; Nakamura Toshikazu; Kaneda Yasufumi; Ogihara Toshio
Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane.
Diabetes 2002;51(8):2604-11.
2002: Tomita Naruya; Morishita Ryuichi; Koike Hiromi; Hashizume Masahide; Notake Mitsue; Fujitani Buichi; Kaneda Yasufumi; Horiuchi Masatsugu; Ogihara Toshio
Therapeutic approach to familial hypercholesterolemia by HVJ-liposomes in LDL receptor knockout mouse.
International journal of molecular medicine 2002;10(2):137-43.
2002: Taniyama Yoshiaki; Morishita Ryuichi; Aoki Motokuni; Hiraoka Kazuya; Yamasaki Keita; Hashiya Naotaka; Matsumoto Kunio; Nakamura Toshikazu; Kaneda Yasufumi; Ogihara Toshio
Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy.
Hypertension 2002;40(1):47-53.
2002: Mori Masaki; Nakagami Hironori; Morishita Ryuichi; Mitsuda Noriaki; Yamamoto Kei; Yoshimura Shin-ichi; Ohkubo Nobutaka; Sato Naoyuki; Ogihara Toshio; Kaneda Yasufumi
N141I mutant presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression.
Life sciences 2002;70(21):2567-80.
2002: Nakamura T; Morishita R; Asai T; Tsuboniwa N; Aoki M; Sakonjo H; Yamasaki K; Hashiya N; Kaneda Y; Ogihara T
Molecular strategy using cis-element 'decoy' of E2F binding site inhibits neointimal formation in porcine balloon-injured coronary artery model.
Gene therapy 2002;9(8):488-94.
2002: Taniyama Y; Tachibana K; Hiraoka K; Aoki M; Yamamoto S; Matsumoto K; Nakamura T; Ogihara T; Kaneda Y; Morishita R
Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle.
Gene therapy 2002;9(6):372-80.
2002: Morishita Ryuichi; Sakaki Minako; Yamamoto Kei; Iguchi Sota; Aoki Motokuni; Yamasaki Keita; Matsumoto Kunio; Nakamura Toshikazu; Lawn Richard; Ogihara Toshio; Kaneda Yasufumi
Impairment of collateral formation in lipoprotein(a) transgenic mice: therapeutic angiogenesis induced by human hepatocyte growth factor gene.
Circulation 2002;105(12):1491-6.
2002: Nakamura Hiroshige; Morishita Ryuichi; Kaneda Yasufumi
Molecular therapy via transcriptional regulation with double-stranded oligodeoxynucleotides as decoys.
In vivo (Athens, Greece) 2002;16(1):45-8.
2002: Kaneda Yasufumi
Viral liposomes. Preparation and use.
Methods in molecular medicine 2002;69():63-72.
2002: Morishita Ryuichi; Kaneda Yasufumi
HVJ (hemagglutinating virus of Japan; Sendai virus)-liposome method.
Methods in enzymology 2002;346():619-27.
2001: Morishita R; Aoki M; Kaneda Y
Decoy oligodeoxynucleotides as novel cardiovascular drugs for cardiovascular disease.
Annals of the New York Academy of Sciences 2001;947():294-301; discussion 301-2.
2001: Miyata T; Yamamoto S; Sakamoto K; Morishita R; Kaneda Y
Novel immunotherapy for peritoneal dissemination of murine colon cancer with macrophage inflammatory protein-1beta mediated by a tumor-specific vector, HVJ cationic liposomes.
Cancer gene therapy 2001;8(11):852-60.
2001: Taniyama Y; Morishita R; Hiraoka K; Aoki M; Nakagami H; Yamasaki K; Matsumoto K; Nakamura T; Kaneda Y; Ogihara T
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic hind limb ischemia model: molecular mechanisms of delayed angiogenesis in diabetes.
Circulation 2001;104(19):2344-50.
2001: Ueno T; Sawa Y; Kitagawa-Sakakida S; Nishimura M; Morishita R; Kaneda Y; Kohmura E; Yoshimine T; Matsuda H
Nuclear factor-kappa B decoy attenuates neuronal damage after global brain ischemia: a future strategy for brain protection during circulatory arrest.
The Journal of thoracic and cardiovascular surgery 2001;122(4):720-7.
2001: Wataya-Kaneda M; Kaneda Y; Hino O; Adachi H; Hirayama Y; Seyama K; Satou T; Yoshikawa K
Cells derived from tuberous sclerosis show a prolonged S phase of the cell cycle and increased apoptosis.
Archives of dermatological research 2001;293(9):460-9.
2001: Kobayashi Y; Fukushima N; Sawa Y; Ohtake S; Matsumiya G; Horiguchi K; Kawaguchi N; Matsuura N; Kaneda Y; Matsuda H
Effects of gene transfection of human bcl-2 on concordant cardiac xenografts in hamster to rat model.
The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi 2001;49(9):570-5.
2001: Morishita R; Aoki M; Kaneda Y; Ogihara T
Gene therapy in vascular medicine: recent advances and future perspectives.
Pharmacology & therapeutics 2001;91(2):105-14.
2001: Aoki M; Morishita R; Hayashi S; Jo N; Matsumoto K; Nakamura T; Kaneda Y; Ogihara T
Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model.
Diabetologia 2001;44(8):1034-42.
2001: Otomo T; Yamamoto S; Morishita R; Kaneda Y
EBV replicon vector system enhances transgene expression in vivo: applications to cancer gene therapy.
The journal of gene medicine 2001;3(4):345-52.
2001: Aoki M; Nata T; Morishita R; Matsushita H; Nakagami H; Yamamoto K; Yamazaki K; Nakabayashi M; Ogihara T; Kaneda Y
Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: antiapoptotic effect of antioxidant agents on endothelial cells.
Hypertension 2001;38(1):48-55.
2001: Kaneko K; Yano M; Yamano T; Tsujinaka T; Miki H; Akiyama Y; Taniguchi M; Fujiwara Y; Doki Y; Inoue M; Shiozaki H; Kaneda Y; Monden M
Detection of peritoneal micrometastases of gastric carcinoma with green fluorescent protein and carcinoembryonic antigen promoter.
Cancer research 2001;61(14):5570-4.
2001: Nakagami H; Morishita R; Yamamoto K; Yoshimura S I; Taniyama Y; Aoki M; Matsubara H; Kim S; Kaneda Y; Ogihara T
Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells.
Diabetes 2001;50(6):1472-81.
2001: Yamamoto K; Morishita R; Hayashi S; Matsushita H; Nakagami H; Moriguchi A; Matsumoto K; Nakamura T; Kaneda Y; Ogihara T
Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells.
Hypertension 2001;37(5):1341-8.
2001: Ura K; Araki M; Saeki H; Masutani C; Ito T; Iwai S; Mizukoshi T; Kaneda Y; Hanaoka F
ATP-dependent chromatin remodeling facilitates nucleotide excision repair of UV-induced DNA lesions in synthetic dinucleosomes.
The EMBO journal 2001;20(8):2004-14.
2001: Tsujie M; Isaka Y; Nakamura H; Kaneda Y; Imai E; Hori M
Prolonged transgene expression in glomeruli using an EBV replicon vector system combined with HVJ liposomes.
Kidney international 2001;59(4):1390-6.
2001: Tsuboniwa N; Morishita R; Hirano T; Fujimoto J; Furukawa S; Kikumori M; Okuyama A; Kaneda Y
Safety evaluation of hemagglutinating virus of Japan--artificial viral envelope liposomes in nonhuman primates.
Human gene therapy 2001;12(5):469-87.
2001: Taniyama Y; Morishita R; Aoki M; Nakagami H; Yamamoto K; Yamazaki K; Matsumoto K; Nakamura T; Kaneda Y; Ogihara T
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease.
Gene therapy 2001;8(3):181-9.
2001: Sakaguchi T; Sawa Y; Fukushima N; Nishimura M; Ichikawa H; Kaneda Y; Matsuda H
A novel strategy of decoy transfection against nuclear factor-kappaB in myocardial preservation.
The Annals of thoracic surgery 2001;71(2):624-9; discussion 629-30.
2001: Nakagami H; Morishita R; Yamamoto K; Taniyama Y; Aoki M; Matsumoto K; Nakamura T; Kaneda Y; Horiuchi M; Ogihara T
Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells.
Hypertension 2001;37(2 Part 2):581-6.
2001: Kanyama H; Tomita N; Yamano T; Aihara T; Miyoshi Y; Ohue M; Sekimoto M; Sakita I; Tamaki Y; Kaneda Y; Senter P D; Monden M
Usefulness of repeated direct intratumoral gene transfer using hemagglutinating virus of Japan-liposome method for cytosine deaminase suicide gene therapy.
Cancer research 2001;61(1):14-8.
2001: Kaneda Y
Improvements in gene therapy technologies.
Molecular urology 2001;5(2):85-9.
2001: Tomita N; Morishita R; Tomita S; Kaneda Y; Higaki J; Ogihara T; Horiuchi M
Inhibition of TNF-alpha, induced cytokine and adhesion molecule. Expression in glomerular cells in vitro and in vivo by transcription factor decoy for NFkappaB.
Experimental nephrology 2001;9(3):181-90.
2000: Takahashi T; Nakamura T; Hayashi A; Kamei M; Nakabayashi M; Okada A A; Tomita N; Kaneda Y; Tano Y
Inhibition of experimental choroidal neovascularization by overexpression of tissue inhibitor of metalloproteinases-3 in retinal pigment epithelium cells.
American journal of ophthalmology 2000;130(6):774-81.
2000: Kamada H; Tsutsumi Y; Yamamoto Y; Kihira T; Kaneda Y; Mu Y; Kodaira H; Tsunoda S I; Nakagawa S; Mayumi T
Antitumor activity of tumor necrosis factor-alpha conjugated with polyvinylpyrrolidone on solid tumors in mice.
Cancer research 2000;60(22):6416-20.
2000: Isaka Y; Tsujie M; Ando Y; Nakamura H; Kaneda Y; Imai E; Hori M
Transforming growth factor-beta 1 antisense oligodeoxynucleotides block interstitial fibrosis in unilateral ureteral obstruction.
Kidney international 2000;58(5):1885-92.
2000: Hayashi K; Nakamura S; Morishita R; Moriguchi A; Aoki M; Matsumoto K; Nakamura T; Kaneda Y; Sakai N; Ogihara T
In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model.
Gene therapy 2000;7(19):1664-71.
2000: Nagaya N; Yokoyama C; Kyotani S; Shimonishi M; Morishita R; Uematsu M; Nishikimi T; Nakanishi N; Ogihara T; Yamagishi M; Miyatake K; Kaneda Y; Tanabe T
Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.
Circulation 2000;102(16):2005-10.
2000: Yamamoto K; Morishita R; Tomita N; Shimozato T; Nakagami H; Kikuchi A; Aoki M; Higaki J; Kaneda Y; Ogihara T
Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model: potential application of ribozyme strategy to treat cardiovascular disease.
Circulation 2000;102(11):1308-14.
2000: Tsunoda S; Kamada H; Yamamoto Y; Ishikawa T; Matsui J; Koizumi K; Kaneda Y; Tsutsumi Y; Ohsugi Y; Hirano T; Mayumi T
Molecular design of polyvinylpyrrolidone-conjugated interleukin-6 for enhancement of in vivo thrombopoietic activity in mice.
Journal of controlled release : official journal of the Controlled Release Society 2000;68(3):335-41.
2000: Kaneda Y
Virosomes: evolution of the liposome as a targeted drug delivery system.
Advanced drug delivery reviews 2000;43(2-3):197-205.
2000: Tomita N; Morishita R; Tomita S; Gibbons G H; Zhang L; Horiuchi M; Kaneda Y; Higaki J; Ogihara T; Dzau V J
Transcription factor decoy for NFkappaB inhibits TNF-alpha-induced cytokine and adhesion molecule expression in vivo.
Gene therapy 2000;7(15):1326-32.
2000: Morishita R; Aoki M; Kaneda Y
Oligonucleotide-based gene therapy for cardiovascular disease: are oligonucleotide therapeutics novel cardiovascular drugs?
Current drug targets 2000;1(1):15-23.
2000: Morishita R; Gibbons G H; Kaneda Y; Ogihara T; Dzau V J
Systemic administration of HVJ viral coat-liposome complex containing human insulin vector decreases glucose level in diabetic mouse: A model of gene therapy.
Biochemical and biophysical research communications 2000;273(2):666-74.
2000: Tomita N; Morishita R; Lan H Y; Yamamoto K; Hashizume M; Notake M; Toyosawa K; Fujitani B; Mu W; Nikolic-Paterson D J; Atkins R C; Kaneda Y; Higaki J; Ogihara T
In vivo administration of a nuclear transcription factor-kappaB decoy suppresses experimental crescentic glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2000;11(7):1244-52.
2000: Yamano T; Ura K; Morishita R; Nakajima H; Monden M; Kaneda Y
Amplification of transgene expression in vitro and in vivo using a novel inhibitor of histone deacetylase.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(6):574-80.
2000: Ura K; Kaneda Y
[DNA methylation and chromatin modification on transcription]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1465-72.
2000: Morishita R; Aoki M; Nakamura S; Higaki J; Kaneda Y; Ogihara T
Gene therapy for cardiovascular disease using hepatocyte growth factor.
Annals of the New York Academy of Sciences 2000;902():369-76.
2000: Hagihara Y; Saitoh Y; Kaneda Y; Kohmura E; Yoshimine T
Widespread gene transfection into the central nervous system of primates.
Gene therapy 2000;7(9):759-63.
2000: Tsujie M; Isaka Y; Ando Y; Akagi Y; Kaneda Y; Ueda N; Imai E; Hori M
Gene transfer targeting interstitial fibroblasts by the artificial viral envelope-type hemagglutinating virus of Japan liposome method.
Kidney international 2000;57(5):1973-80.
2000: Arai T; Abe K; Matsuoka H; Yoshida M; Mori M; Goya S; Kida H; Nishino K; Osaki T; Tachibana I; Kaneda Y; Hayashi S
Introduction of the interleukin-10 gene into mice inhibited bleomycin-induced lung injury in vivo.
American journal of physiology. Lung cellular and molecular physiology 2000;278(5):L914-22.
2000: Morishita R; Gibbons G H; Tomita N; Zhang L; Kaneda Y; Ogihara T; Dzau V J
Antisense oligodeoxynucleotide inhibition of vascular angiotensin-converting enzyme expression attenuates neointimal formation: evidence for tissue angiotensin-converting enzyme function.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):915-22.
2000: Matsushita H; Morishita R; Aoki M; Tomita N; Taniyama Y; Nakagami H; Shimozato T; Higaki J; Kaneda Y; Ogihara T
Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells.
Circulation 2000;101(12):1447-52.
2000: Aoki M; Morishita R; Taniyama Y; Kida I; Moriguchi A; Matsumoto K; Nakamura T; Kaneda Y; Higaki J; Ogihara T
Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets.
Gene therapy 2000;7(5):417-27.
2000: Sakuma-Mochizuki J; Yoshida M; Abe K; Arai T; Mori M; Kaneda Y; Hayashi S
Changes in pulmonary histology and exfoliated bronchoalveolar cells induced by in vivo introduction of the tumor necrosis factor-alpha gene.
Inflammation 2000;24(1):11-9.
2000: Kaneda Y; Saeki Y; Nakabayashi M; Zhou W Z; Kaneda M W; Morishita R
Enhancement of transgene expression by cotransfection of oriP plasmid with EBNA-1 expression vector.
Human gene therapy 2000;11(3):471-9.
2000: Higaki J; Aoki M; Morishita R; Kida I; Taniyama Y; Tomita N; Yamamoto K; Moriguchi A; Kaneda Y; Ogihara T
In vivo evidence of the importance of cardiac angiotensin-converting enzyme in the pathogenesis of cardiac hypertrophy.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):428-34.
2000: Aoki M; Morishita R; Taniyama Y; Kaneda Y; Ogihara T
Therapeutic angiogenesis induced by hepatocyte growth factor: potential gene therapy for ischemic diseases.
Journal of atherosclerosis and thrombosis 2000;7(2):71-6.
1999: Tomita T; Takeuchi E; Tomita N; Morishita R; Kaneko M; Yamamoto K; Nakase T; Seki H; Kato K; Kaneda Y; Ochi T
Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapy.
Arthritis and rheumatism 1999;42(12):2532-42.
1999: Zhou W Z; Hoon D S; Huang S K; Fujii S; Hashimoto K; Morishita R; Kaneda Y
RNA melanoma vaccine: induction of antitumor immunity by human glycoprotein 100 mRNA immunization.
Human gene therapy 1999;10(16):2719-24.
1999: Yoshida M; Sakuma-Mochizuki J; Abe K; Arai T; Mori M; Goya S; Matsuoka H; Hayashi S; Kaneda Y; Kishimoto T
In vivo gene transfer of an extracellular domain of platelet-derived growth factor beta receptor by the HVJ-liposome method ameliorates bleomycin-induced pulmonary fibrosis.
Biochemical and biophysical research communications 1999;265(2):503-8.
1999: Suzuki K; Sawa Y; Ichikawa H; Kaneda Y; Matsuda H
Myocardial protection with endogenous overexpression of manganese superoxide dismutase.
The Annals of thoracic surgery 1999;68(4):1266-71.
1999: Zhou W Z; Kaneda Y; Huang S; Morishita R; Hoon D
Protective immunization against melanoma by gp100 DNA-HVJ-liposome vaccine.
Gene therapy 1999;6(10):1768-73.
1999: Kaneda Y; Morishita R
[Gene therapy of cardiovascular disorders]
Human cell : official journal of Human Cell Research Society 1999;12(3):109-14.
1999: Kawahira Y; Sawa Y; Nishimura M; Sakakida S; Ueda H; Kaneda Y; Matsuda H
Gene transfection of beta 2-adrenergic receptor into the normal rat heart enhances cardiac response to beta-adrenergic agonist.
The Journal of thoracic and cardiovascular surgery 1999;118(3):446-51.
1999: Nakamura S; Moriguchi A; Morishita R; Yamada K; Nishii T; Tomita N; Ohishi M; Kaneda Y; Higaki J; Ogihara T
Activation of the brain angiotensin system by in vivo human angiotensin-converting enzyme gene transfer in rats.
Hypertension 1999;34(2):302-8.
1999: Aoki M; Morishita R; Matsushita H; Hayashi S; Nakagami H; Yamamoto K; Moriguchi A; Kaneda Y; Higaki J; Ogihara T
Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells. Potential role of p53 in regulation of vascular smooth muscle cell growth.
Hypertension 1999;34(2):192-200.
1999: Nishii T; Moriguchi A; Morishita R; Yamada K; Nakamura S; Tomita N; Kaneda Y; Fukamizu A; Mikami H; Higaki J; Ogihara T
Angiotensinogen gene-activating elements regulate blood pressure in the brain.
Circulation research 1999;85(3):257-63.
1999: Kaneda Y; Saeki Y; Morishita R
Gene therapy using HVJ-liposomes: the best of both worlds?
Molecular medicine today 1999;5(7):298-303.
1999: Ueda H; Sawa Y; Matsumoto K; Kitagawa-Sakakida S; Kawahira Y; Nakamura T; Kaneda Y; Matsuda H
Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart.
The Annals of thoracic surgery 1999;67(6):1726-31.
1999: Kamada H; Tsutsumi Y; Tsunoda S; Kihira T; Kaneda Y; Yamamoto Y; Nakagawa S; Horisawa Y; Mayumi T
Molecular design of conjugated tumor necrosis factor-alpha: synthesis and characteristics of polyvinyl pyrrolidone modified tumor necrosis factor-alpha.
Biochemical and biophysical research communications 1999;257(2):448-53.
1999: Sato M; Saeki Y; Tanaka K; Kaneda Y
Ribosome-associated protein LBP/p40 binds to S21 protein of 40S ribosome: analysis using a yeast two-hybrid system.
Biochemical and biophysical research communications 1999;256(2):385-90.
1999: Mu Y; Kamada H; Kaneda Y; Yamamoto Y; Kodaira H; Tsunoda S; Tsutsumi Y; Maeda M; Kawasaki K; Nomizu M; Yamada Y; Mayumi T
Bioconjugation of laminin peptide YIGSR with poly(styrene co-maleic acid) increases its antimetastatic effect on lung metastasis of B16-BL6 melanoma cells.
Biochemical and biophysical research communications 1999;255(1):75-9.
1999: Isaka Y; Akagi Y; Ando Y; Tsujie M; Sudo T; Ohno N; Border W A; Noble N A; Kaneda Y; Hori M; Imai E
Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis.
Kidney international 1999;55(2):465-75.
1999: Todaka T; Yokoyama C; Yanamoto H; Hashimoto N; Nagata I; Tsukahara T; Hara S; Hatae T; Morishita R; Aoki M; Ogihara T; Kaneda Y; Tanabe T
Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats.
Stroke; a journal of cerebral circulation 1999;30(2):419-26.
1999: Yoshida M; Hayashi S; Sakuma-Mochizuki J; Abe K; Arai T; Mori M; Goya S; Matsuoka H; Kaneda Y; Kishimoto T
Introduction of plasmid DNA and oligonucleotides into lung epithelial cells by the hemagglutinating virus of Japan (HVJ)-liposome method.
Somatic cell and molecular genetics 1999;25(1):49-57.
1999: Kaneda Y
Development of a novel fusogenic viral liposome system (HVJ-liposomes) and its applications to the treatment of acquired diseases.
Molecular membrane biology 1999;16(1):119-22.
1999: Ozkan I; Shino K; Nakamura N; Natsuume T; Matsumoto N; Horibe S; Tomita T; Kaneda Y; Ochi T
Direct in vivo gene transfer to healing rat patellar ligament by intra-arterial delivery of haemagglutinating virus of Japan liposomes.
European journal of clinical investigation 1999;29(1):63-7.
1998: Kinoshita K; Kaneda Y; Sato M; Saeki Y; Wataya-Kaneda M; Hoffmann A
LBP-p40 binds DNA tightly through associations with histones H2A, H2B, and H4.
Biochemical and biophysical research communications 1998;253(2):277-82.
1998: Sawa Y; Kaneda Y; Bai H Z; Suzuki K; Fujimoto J; Morishita R; Matsuda H
Efficient transfer of oligonucleotides and plasmid DNA into the whole heart through the coronary artery.
Gene therapy 1998;5(11):1472-80.
1998: Kawahira Y; Sawa Y; Nishimura M; Sakakida S; Ueda H; Kaneda Y; Matsuda H
In vivo transfer of a beta 2-adrenergic receptor gene into the pressure-overloaded rat heart enhances cardiac response to beta-adrenergic agonist.
Circulation 1998;98(19 Suppl):II262-7; discussion II267-8.
1998: Morishita R; Yamada S; Yamamoto K; Tomita N; Kida I; Sakurabayashi I; Kikuchi A; Kaneda Y; Lawn R; Higaki J; Ogihara T
Novel therapeutic strategy for atherosclerosis: ribozyme oligonucleotides against apolipoprotein(a) selectively inhibit apolipoprotein(a) but not plasminogen gene expression.
Circulation 1998;98(18):1898-904.
1998: Nakamura N; Shino K; Natsuume T; Horibe S; Matsumoto N; Kaneda Y; Ochi T
Early biological effect of in vivo gene transfer of platelet-derived growth factor (PDGF)-B into healing patellar ligament.
Gene therapy 1998;5(9):1165-70.
1998: Bai H Z; Sawa Y; Zhang W D; Yamakawa T; Morishita R; Kaneda Y; Matsuda H
Gene transfer to vein graft wall by HVJ-liposome method: time course and localization of gene expression.
The Annals of thoracic surgery 1998;66(3):814-9; discussion 819-20.
1998: Saeki Y; Wataya-Kaneda M; Tanaka K; Kaneda Y
Sustained transgene expression in vitro and in vivo using an Epstein-Barr virus replicon vector system combined with HVJ liposomes.
Gene therapy 1998;5(8):1031-7.
1998: Morishita R; Yamada S; Higaki J; Tomita N; Kida I; Aoki M; Moriguchi A; Hayashi S; Sakurabayashi I; Kaneda Y; Ogihara T
Conditioned medium from HepG2 cells transfected with human apolipoprotein(a) gene stimulates growth of human vascular smooth muscle cells: effects of overexpression of human apolipoprotein(a) gene.
Hypertension 1998;32(2):215-22.
1998: Morishita R; Yamamoto K; Yamada S; Matsushita H; Tomita N; Sakurabayashi I; Kaneda Y; Moriguchi A; Higaki J; Ogihara T
Stimulatory effect of lipoprotein (a) on proliferation of human mesangial cells: role of lipoprotein (a) in renal disease.
Biochemical and biophysical research communications 1998;249(2):313-20.
1998: Bai H; Morishita R; Kida I; Yamakawa T; Zhang W; Aoki M; Matsushita H; Noda A; Nagai R; Kaneda Y; Higaki J; Ogihara T; Sawa Y; Matsuda H
Inhibition of intimal hyperplasia after vein grafting by in vivo transfer of human senescent cell-derived inhibitor-1 gene.
Gene therapy 1998;5(6):761-9.
1998: Suzuki K; Sawa Y; Kaneda Y; Ichikawa H; Shirakura R; Matsuda H
Overexpressed heat shock protein 70 attenuates hypoxic injury in coronary endothelial cells.
Journal of molecular and cellular cardiology 1998;30(6):1129-36.
1998: Isaka Y; Akagi Y; Kaneda Y; Imai E
The HVJ liposome method.
Experimental nephrology 1998;6(2):144-7.
1998: Suzuki K; Sawa Y; Kaneda Y; Ichihara H; Shirakura R; Matsuda H
[In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat]
Journal of cardiology 1998;31(3):187-8.
1998: Kaneda Y; Kinoshita K; Sato M; Saeki Y; Yamada R; Wataya-Kaneda M; Tanaka K
The induction of apoptosis in HeLa cells by the loss of LBP-p40.
Cell death and differentiation 1998;5(1):20-8.
1998: Imai E; Isaka Y; Akagi Y; Kaneda Y; Hori M
Gene transfer and kidney disease.
Journal of nephrology 1998;11(1):16-9.
1998: Matsushita H; Morishita R; Kida I; Aoki M; Hayashi S; Tomita N; Yamamoto K; Moriguchi A; Noda A; Kaneda Y; Higaki J; Ogihara T
Inhibition of growth of human vascular smooth muscle cells by overexpression of p21 gene through induction of apoptosis.
Hypertension 1998;31(1 Pt 2):493-8.
1998: Kaneda Y; Yamamoto Y; Kamada H; Tsunoda S; Tsutsumi Y; Hirano T; Mayumi T
Antitumor activity of tumor necrosis factor alpha conjugated with divinyl ether and maleic anhydride copolymer on solid tumors in mice.
Cancer research 1998;58(2):290-5.
1997: Saeki Y; Matsumoto N; Nakano Y; Mori M; Awai K; Kaneda Y
Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): reciprocal effect of cationic lipid for in vitro and in vivo gene transfer.
Human gene therapy 1997;8(17):2133-41.
1997: Sawa Y; Morishita R; Suzuki K; Kagisaki K; Kaneda Y; Maeda K; Kadoba K; Matsuda H
A novel strategy for myocardial protection using in vivo transfection of cis element 'decoy' against NFkappaB binding site: evidence for a role of NFkappaB in ischemia-reperfusion injury.
Circulation 1997;96(9 Suppl):II-280-4; discussion II-285.
1997: Kaneda Y; Yamamoto Y; Tsunoda S; Kamada H; Tsutsumi Y; Hirano T; Mayumi T
Bioconjugation of tumor necrosis factor-alpha with the copolymer of divinyl ether and maleic anhydride increasing its antitumor potency.
Biochemical and biophysical research communications 1997;239(1):160-5.
1997: Mabuchi E; Shimizu K; Miyao Y; Kaneda Y; Kishima H; Tamura M; Ikenaka K; Hayakawa T
Gene delivery by HVJ-liposome in the experimental gene therapy of murine glioma.
Gene therapy 1997;4(8):768-72.
1997: Kaneda Y; Yamamoto Y; Okada N; Tsutsuml Y; Nakagawa S; Kakiuch M; Maeda M; Kawasaki K; Mayumi T
Antimetastatic effect of synthetic Glu-Ile-Leu-Asp-Val peptide derivatives containing D-amino acids.
Anti-cancer drugs 1997;8(7):702-7.
1997: Morishita R; Sugimoto T; Aoki M; Kida I; Tomita N; Moriguchi A; Maeda K; Sawa Y; Kaneda Y; Higaki J; Ogihara T
In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction.
Nature medicine 1997;3(8):894-9.
1997: Kaneda Y
[Liposome-mediated gene delivery]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1806-13.
1997: Takeda S; Sawa Y; Minami M; Kaneda Y; Fujii Y; Shirakura R; Yanagisawa M; Matsuda H
Experimental bronchiolitis obliterans induced by in vivo HVJ-liposome-mediated endothelin-1 gene transfer.
The Annals of thoracic surgery 1997;63(6):1562-7.
1997: Tomita T; Hashimoto H; Tomita N; Morishita R; Lee S B; Hayashida K; Nakamura N; Yonenobu K; Kaneda Y; Ochi T
In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes.
Arthritis and rheumatism 1997;40(5):901-6.
1997: Kaneda Y; Morishita R; Dzau V J
Prevention of restenosis by gene therapy.
Annals of the New York Academy of Sciences 1997;811():299-308; discussion 308-10.
1997: Aoki M; Morishita R; Muraishi A; Moriguchi A; Sugimoto T; Maeda K; Dzau V J; Kaneda Y; Higaki J; Ogihara T
Efficient in vivo gene transfer into the heart in the rat myocardial infarction model using the HVJ (Hemagglutinating Virus of Japan)--liposome method.
Journal of molecular and cellular cardiology 1997;29(3):949-59.
1997: Imai E; Isaka Y; Akagi Y; Kaneda Y
Gene transfer into the glomerulus by the hemagglutinating virus of Japan-liposome method.
Experimental nephrology 1997;5(2):112-7.
1997: Sawa Y; Kadoba K; Suzuki K; Bai H Z; Kaneda Y; Shirakura R; Matsuda H
Efficient gene transfer method into the whole heart through the coronary artery with hemagglutinating virus of Japan liposome.
The Journal of thoracic and cardiovascular surgery 1997;113(3):512-8; discussion 518-9.
1997: Kaneda Y; Morishita R
[Development of in vivo gene transfer methods towards future gene therapy]
Rinsho byori. The Japanese journal of clinical pathology 1997;45(2):99-105.
1997: Aoki M; Morishita R; Higaki J; Moriguchi A; Hayashi S; Matsushita H; Kida I; Tomita N; Sawa Y; Kaneda Y; Ogihara T
Survival of grafts of genetically modified cardiac myocytes transfected with FITC-labeled oligodeoxynucleotides and the beta-galactosidase gene in the noninfarcted area, but not the myocardial infarcted area.
Gene therapy 1997;4(2):120-7.
1997: Aoki M; Morishita R; Higaki J; Moriguchi A; Kida I; Hayashi S; Matsushita H; Kaneda Y; Ogihara T
In vivo transfer efficiency of antisense oligonucleotides into the myocardium using HVJ-liposome method.
Biochemical and biophysical research communications 1997;231(3):540-5.
1997: Tsutsumi Y; Tsunoda S; Kamada H; Kihira T; Kaneda Y; Ohsugi Y; Mayumi T
PEGylation of interleukin-6 effectively increases its thrombopoietic potency.
Thrombosis and haemostasis 1997;77(1):168-73.
1996: Sato M; Kinoshita K; Kaneda Y; Saeki Y; Iwamatsu A; Tanaka K
Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40).
Biochemical and biophysical research communications 1996;229(3):896-901.
1996: Kaneda Y
[Structure and function of higher eukaryote chromosome]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2219-29.
1996: Yamada K; Moriguchi A; Morishita R; Aoki M; Nakamura Y; Mikami H; Oshima T; Ninomiya M; Kaneda Y; Higaki J; Ogihara T
Efficient oligonucleotide delivery using the HVJ-liposome method in the central nervous system.
The American journal of physiology 1996;271(5 Pt 2):R1212-20.
1996: Tsutsumi Y; Tsunoda S; Kaneda Y; Kamada H; Kihira T; Nakagawa S; Yamamoto Y; Horisawa Y; Mayumi T
In vivo anti-tumor efficacy of polyethylene glycol-modified tumor necrosis factor-alpha against tumor necrosis factor-resistant tumors.
Japanese journal of cancer research : Gann 1996;87(10):1078-85.
1996: Kaneda Y
[Development of non-viral gene delivery system and its applications]
Nippon rinsho. Japanese journal of clinical medicine 1996;54(10):2829-38.
1996: Hayashi S I; Morishita R; Aoki M; Moriguchi A; Kida I; Nakajima M; Kaneda Y; Higaki J; Ogihara T
In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid.
Gene therapy 1996;3(10):878-85.
1996: Tsutsumi Y; Tsunoda S; Kamada H; Kihira T; Nakagawa S; Kaneda Y; Kanamori T; Mayumi T
Molecular design of hybrid tumour necrosis factor-alpha. II: The molecular size of polyethylene glycol-modified tumour necrosis factor-alpha affects its anti-tumour potency.
British journal of cancer 1996;74(7):1090-5.
1996: Tsutsumi Y; Kihira T; Tsunoda S; Kamada H; Nakagawa S; Kaneda Y; Kanamori T; Mayumi T
Molecular design of hybrid tumor necrosis factor-alpha III: polyethylene glycol-modified tumor necrosis factor-alpha has markedly enhanced antitumor potency due to longer plasma half-life and higher tumor accumulation.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1006-11.
1996: Okada N; Kaneda Y; Miyamoto H; Yamamoto Y; Mizuguchi H; Tsutsumi Y; Nakagawa S; Mayumi T
Selective enhancement by tumor necrosis factor-alpha of vascular permeability of new blood vessels induced with agarose hydrogel-entrapped Meth-A fibrosarcoma cells.
Japanese journal of cancer research : Gann 1996;87(8):831-6.
1996: Akagi Y; Isaka Y; Arai M; Kaneko T; Takenaka M; Moriyama T; Kaneda Y; Ando A; Orita Y; Kamada T; Ueda N; Imai E
Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis.
Kidney international 1996;50(1):148-55.
1996: Tomita N; Morishita R; Higaki J; Tomita S; Aoki M; Kaneda Y; Ogihara T
Sustained transgene expression by transfection of renin gene into liver of neonates.
Biochemical and biophysical research communications 1996;224(1):43-9.
1996: Yanagihara I; Inui K; Dickson G; Turner G; Piper T; Kaneda Y; Okada S
Expression of full-length human dystrophin cDNA in mdx mouse muscle by HVJ-liposome injection.
Gene therapy 1996;3(6):549-53.
1996: Tomita N; Morishita R; Higaki J; Tomita S; Aoki M; Ogihara T; Kaneda Y
In vivo gene transfer of insulin gene into neonatal rats by the HVJ-liposome method resulted in sustained transgene expression.
Gene therapy 1996;3(6):477-82.
1996: Morishita R; Higaki J; Tomita N; Aoki M; Moriguchi A; Tamura K; Murakami K; Kaneda Y; Ogihara T
Role of transcriptional cis-elements, angiotensinogen gene-activating elements, of angiotensinogen gene in blood pressure regulation.
Hypertension 1996;27(3 Pt 2):502-7.
1996: Hayashi S; Morishita R; Higaki J; Aoki M; Moriguchi A; Kida I; Yoshiki S; Matsumoto K; Nakamura T; Kaneda Y; Ogihara T
Autocrine-paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells.
Biochemical and biophysical research communications 1996;220(3):539-45.
1996: Nakamura N; Horibe S; Matsumoto N; Tomita T; Natsuume T; Kaneda Y; Shino K; Ochi T
Transient introduction of a foreign gene into healing rat patellar ligament.
The Journal of clinical investigation 1996;97(1):226-31.
1996: Morishita R; Higaki J; Aoki M; Hayashi S; Kida I; Kaneda Y; Ogihara T
Novel strategy of gene therapy in cardiovascular disease with HVJ-liposome method.
Contributions to nephrology 1996;118():254-64.
1996: Imai E; Isaka Y; Akagi Y; Arai M; Moriyama T; Takenaka M; Kaneko T; Horio M; Ando A; Orita Y; Kaneda Y; Ueda N; Kamada T
Application of antisense oligodeoxynucleotides (ODNs) for the intervention of kidney disease. Antisense ODNs for transforming growth factor-beta-suppressed glomerulosclerosis in experimental glomerulonephritis.
Contributions to nephrology 1996;118():86-93.
1995: Tomita N; Morishita R; Higaki J; Tomita S; Aoki M; Kaneda Y; Ogihara T
Effect of angiotensinogen on blood pressure regulation in normotensive rats: application of a loss of function approach.
Journal of hypertension 1995;13(12 Pt 2):1767-74.
1995: Wataya-Kaneda M; Hashimoto K; Yoshikawa K; Kaneda Y
The loss of 40-kDa chromosomal protein in tuberous sclerosis lesions.
Biochemical and biophysical research communications 1995;217(2):599-607.
1995: Sawa Y; Suzuki K; Bai H Z; Shirakura R; Morishita R; Kaneda Y; Matsuda H
Efficiency of in vivo gene transfection into transplanted rat heart by coronary infusion of HVJ liposome.
Circulation 1995;92(9 Suppl):II479-82.
1995: Hara S; Morishita R; Tone Y; Yokoyama C; Inoue H; Kaneda Y; Ogihara T; Tanabe T
Overexpression of prostacyclin synthase inhibits growth of vascular smooth muscle cells.
Biochemical and biophysical research communications 1995;216(3):862-7.
1995: Kaneda Y
[Induction of hepatitis in rats injected with HBV-DNA using HVJ-liposome]
Nippon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 2):104-10.
1995: Kaneda Y; Morishita R; Tomita N
Increased expression of DNA cointroduced with nuclear protein in adult rat liver.
Journal of molecular medicine (Berlin, Germany) 1995;73(6):289-97.
1995: Arai M; Wada A; Isaka Y; Akagi Y; Sugiura T; Miyazaki M; Moriyama T; Kaneda Y; Naruse K; Naruse M
In vivo transfection of genes for renin and angiotensinogen into the glomerular cells induced phenotypic change of the mesangial cells and glomerular sclerosis.
Biochemical and biophysical research communications 1995;206(2):525-32.
1995: Kaneda Y; Yamamoto S; Kihira T; Tsutsumi Y; Nakagawa S; Miyake M; Kawasaki K; Mayumi T
Synthetic cell-adhesive laminin peptide YIGSR conjugated with polyethylene glycol has improved antimetastatic activity due to a longer half-life in blood.
Invasion & metastasis 1995;15(3-4):156-62.
1994: Yamamoto S; Kaneda Y; Okada N; Nakagawa S; Kubo K; Inoue S; Maeda M; Yamashiro Y; Kawasaki K; Mayumi T
Antimetastatic effects of synthetic peptides containing the core sequence of the type III connecting segment domain (IIICS) of fibronectin.
Anti-cancer drugs 1994;5(4):424-8.
1994: Imai E; Isaka Y; Fujiwara Y; Kaneda Y; Kamada T; Ueda N
Introduction of a foreign gene into the kidney in vivo: development of glomerulosclerosis by the transfection of genes for PDGF and TGF-beta.
Contributions to nephrology 1994;107():205-15.
1994: Tomita N; Higaki J; Ogihara T; Kondo T; Kaneda Y
A novel gene-transfer technique mediated by HVJ (Sendai virus), nuclear protein, and liposomes.
Cancer detection and prevention 1994;18(6):485-91.
1993: Isaka Y; Fujiwara Y; Ueda N; Kaneda Y; Kamada T; Imai E
Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.
The Journal of clinical investigation 1993;92(6):2597-601.
1993: Fujita S; Shin E; Nakamura T; Kurahashi H; Kaneda Y; Tanaka K; Mori T; Takai S; Nishisho I
Construction of radiation-reduced hybrids and their use in mapping of microclones from chromosome 10p11.2-q11.2.
The Japanese journal of human genetics 1993;38(4):361-70.
1993: Tomita N; Higaki J; Kaneda Y; Yu H; Morishita R; Mikami H; Ogihara T
Hypertensive rats produced by in vivo introduction of the human renin gene.
Circulation research 1993;73(5):898-905.
1993: Kaneda Y; Kinoshita K; Sato M; Tanaka K; Kaneda Y
The analysis of 40 kDa nuclear protein, p40, in interphase cells and mitotic cells.
Journal of cell science 1993;106 ( Pt 3)():741-8.
1993: Kaneda Y; Kinoshita K; Sato M; Tanaka K; Kaneda Y
The analysis of 40 kDa nuclear protein, p40, in interphase cells and mitotic cells.
Journal of cell science 1993;106 ( Pt 3)():741-8.
1993: Kaneda Y; Kato K; Nakanishi M; Uchida T
Introduction of plasmid DNA and nuclear protein into cells by using erythrocyte ghosts, liposomes, and Sendai virus.
Methods in enzymology 1993;221():317-27.
1992: Tomita N; Higaki J; Kaneda Y; Ogihara T
[Direct in vivo gene introduction into rat kidney]
Nippon rinsho. Japanese journal of clinical medicine 1992;50(12):2874-8.
1992: Yoneda Y; Semba T; Kaneda Y; Noble R L; Matsuoka Y; Kurihara T; Okada Y; Imamoto N
A long synthetic peptide containing a nuclear localization signal and its flanking sequences of SV40 T-antigen directs the transport of IgM into the nucleus efficiently.
Experimental cell research 1992;201(2):313-20.
1992: Tomita N; Higaki J; Morishita R; Kato K; Mikami H; Kaneda Y; Ogihara T
Direct in vivo gene introduction into rat kidney.
Biochemical and biophysical research communications 1992;186(1):129-34.
1991: Kato K; Kaneda Y; Sakurai M; Nakanishi M; Okada Y
Direct injection of hepatitis B virus DNA into liver induced hepatitis in adult rats.
The Journal of biological chemistry 1991;266(33):22071-4.
1991: Yoneda A; Yoneda Y; Kaneda Y; Hayes H; Uchida T; Okada Y
Monoclonal antibodies specific for human chromosome 5 obtained with a monochromosomal hybrid can be used to sort out cells containing the chromosome with a FACS.
Chromosoma 1991;100(3):187-92.
1991: Kato K; Nakanishi M; Kaneda Y; Uchida T; Okada Y
Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified liposome method.
The Journal of biological chemistry 1991;266(6):3361-4.
1989: Kaneda Y; Iwai K; Uchida T
Introduction and expression of the human insulin gene in adult rat liver.
The Journal of biological chemistry 1989;264(21):12126-9.
1989: Kaneda Y; Iwai K; Uchida T
Increased expression of DNA cointroduced with nuclear protein in adult rat liver.
Science (New York, N.Y.) 1989;243(4889):375-8.
1987: Kaneda Y; Uchida T; Kim J; Ishiura M; Okada Y
The improved efficient method for introducing macromolecules into cells using HVJ (Sendai virus) liposomes with gangliosides.
Experimental cell research 1987;173(1):56-69.
1987: Hayes H; Kaneda Y; Uchida T; Okada Y
Regional assignment of the gene for diphtheria toxin sensitivity using subchromosomal fragments in microcell hybrids.
Chromosoma 1987;96(1):26-32.

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