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Shiro Kanegasaki

Research Profile

Chemicals & Drugs

Anatomy

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Chronic Granulomatous Disease

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Arya Biragyn; Monica Bodogai; Sinan R Denny-Brown; Cory M Hogaboam; Shiro Kanegasaki; Purevdorj B Olkhanud; Nitin Puri; Katarzyna Wejksza; Koichi Ayukawa; Catalina Lee-Chang
Inhibition of Lung Metastasis by Chemokine CCL17-mediated In Vivo Silencing of Genes in CCR4+ Tregs.
Maho Kodama; Katsura Tsukamoto; Kimiko Yoshida; Kazunori Aoki; Shiro Kanegasaki; Gary Quinn
Embryonic stem cell transplantation correlates with endogenous neurogenin 3 expression and pancreas regeneration in streptozotocin-injured mice.
Etsuko Toda; Yuya Terashima; Tsuyoshi Sato; Kenzo Hirose; Shiro Kanegasaki; Kouji Matsushima
FROUNT is a common regulator of CCR2 and CCR5 signaling to control directional migration.

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2013: Arya Biragyn; Monica Bodogai; Sinan R Denny-Brown; Cory M Hogaboam; Shiro Kanegasaki; Purevdorj B Olkhanud; Nitin Puri; Katarzyna Wejksza; Koichi Ayukawa; Catalina Lee-Chang
Inhibition of Lung Metastasis by Chemokine CCL17-mediated In Vivo Silencing of Genes in CCR4+ Tregs.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2013;36(4):258-67.
2009: Maho Kodama; Katsura Tsukamoto; Kimiko Yoshida; Kazunori Aoki; Shiro Kanegasaki; Gary Quinn
Embryonic stem cell transplantation correlates with endogenous neurogenin 3 expression and pancreas regeneration in streptozotocin-injured mice.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009;57(12):1149-58.
2009: Etsuko Toda; Yuya Terashima; Tsuyoshi Sato; Kenzo Hirose; Shiro Kanegasaki; Kouji Matsushima
FROUNT is a common regulator of CCR2 and CCR5 signaling to control directional migration.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(10):6387-94.
2009: Nao Nitta; Yoshiko Aoki; Yasushi Isogawa; Tomoko Tsuchiya; Shiro Kanegasaki
Image analysis of mast cell degranulation in a concentration gradient of stimuli formed in the channel between a glass plate and a silicon substrate.
European journal of cell biology 2009;88(9):541-9.
2008: Ayaka Ito; Takayoshi Suganami; Akira Yamauchi; Mikako Degawa-Yamauchi; Miyako Tanaka; Ryuji Kouyama; Yuko Kobayashi; Nao Nitta; Kazuki Yasuda; Yukio Hirata; William Kuziel; Motohiro Takeya; Shiro Kanegasaki; Yasutomi Kamei; Yoshihiro Ogawa
Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue.
The Journal of biological chemistry 2008;283(51):35715-23.
2008: Futoshi Kuribayashi; Satoru Tsuruta; Tsuyoshi Yamazaki; Hiroyuki Nunoi; Shinobu Imajoh-Ohmi; Shiro Kanegasaki; Michio Nakamura
Cell adhesion markedly increases lucigenin-enhanced chemiluminescence of the phagocyte NADPH oxidase.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(12):1249-56.
2008: Kanako Saito; Mie Torii; Ning Ma; Tomoko Tsuchiya; Linan Wang; Tomohide Hori; Daisuke Nagakubo; Nao Nitta; Shiro Kanegasaki; Kunio Hieshima; Osamu Yoshie; Esteban C Gabazza; Naoyuki Katayama; Hiroshi Shiku; Kagemasa Kuribayashi; Takuma Kato
Differential regulatory function of resting and preactivated allergen-specific CD4+ CD25+ regulatory T cells in Th2-type airway inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):6889-97.
2008: Kenshiro Shiraishi; Yoshiro Ishiwata; Keiichi Nakagawa; Shoji Yokochi; Chiho Taruki; Teruo Akuta; Kuni Ohtomo; Kouji Matsushima; Takuya Tamatani; Shiro Kanegasaki
Enhancement of antitumor radiation efficacy and consistent induction of the abscopal effect in mice by ECI301, an active variant of macrophage inflammatory protein-1alpha.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1159-66.
2008: Maho Kodama; Fumitaka Takeshita; Shiro Kanegasaki; Takahiro Ochiya; Gary Quinn
Pancreatic endocrine and exocrine cell ontogeny from renal capsule transplanted embryonic stem cells in streptozocin-injured mice.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2008;56(1):33-44.
2007: Nao Nitta; Tomoko Tsuchiya; Akira Yamauchi; Takuya Tamatani; Shiro Kanegasaki
Quantitative analysis of eosinophil chemotaxis tracked using a novel optical device -- TAXIScan.
Journal of immunological methods 2007;320(1-2):155-63.
2007: Alexandre Vasilescu; Y Terashima; M Enomoto; Simon Heath; V Poonpiriya; H Gatanaga; Hervé Do; Gora Diop; Thomas Hirtzig; Prasert Auewarakul; Darat Lauhakirti; Thanyachai Sura; P Charneau; S Marullo; Amu Therwath; S Oka; Shiro Kanegasaki; Mark Lathrop; K Matsushima; Jean-François Zagury; Fumihiko MATSUDA
A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3354-9.
2006: Fumitaka Takeshita; M Kodama; Hanako Yamamoto; Y Ikarashi; S Ueda; Takumi Teratani; Yusuke Yamamoto; T Tamatani; Shiro Kanegasaki; Takahiro Ochiya; Gary Quinn
Streptozotocin-induced partial beta cell depletion in nude mice without hyperglycaemia induces pancreatic morphogenesis in transplanted embryonic stem cells.
Diabetologia 2006;49(12):2948-58.
2005: Yuya Terashima; Nobuyuki Onai; Masako Murai; Masahiko Enomoto; Vongsakorn Poonpiriya; Tsuyoshi Hamada; Kazushi Motomura; Makiko Suwa; Taichi Ezaki; Tatsuya Haga; Shiro Kanegasaki; Kouji Matsushima
Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis.
Nature immunology 2005;6(8):827-35.
2005: Hiroyuki Nunoi; Maria Regina Mercado; Tomoyuki Mizukami; Kenji Okajima; Tsuneo Morishima; Hiroshi Sakata; Shinichi Nakayama; Seiji Mori; Masatoshi Hayashi; Hiromi Mori; Seiichi Kagimoto; Shiro Kanegasaki; Keisuke Watanabe; Naoto Adachi; Fumio Endo
Apoptosis under hypercytokinemia is a possible pathogenesis in influenza-associated encephalopathy.
Pediatrics international : official journal of the Japan Pediatric Society 2005;47(2):175-9.
2005: Junko Sawada; Shinya Shimizu; Takuya Tamatani; Shiro Kanegasaki; Hirohisa Saito; Akane Tanaka; Naotomo Kambe; Tatsutoshi Nakahata; Hiroshi Matsuda
Stem cell factor has a suppressive activity to IgE-mediated chemotaxis of mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3626-32.
2003: Shiro Kanegasaki; Yuka Nomura; Nao Nitta; Shuichi Akiyama; Takuya Tamatani; Yasuhiro Goshoh; Takashi Yoshida; Tsuyoshi Sato; Yuji Kikuchi
A novel optical assay system for the quantitative measurement of chemotaxis.
Journal of immunological methods 2003;282(1-2):1-11.
2002: Kaoru Azumi; Futoshi Kuribayashi; Shiro Kanegasaki; Hideyoshi Yokosawa
Zymosan induces production of superoxide anions by hemocytes of the solitary ascidian Halocynthia roretzi.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2002;133(4):567-74.
2001: Y Inoue; M Yagisawa; Kumiko Saeki; Shinobu Imajoh-Ohmi; Shiro Kanegasaki; Akira Yuo
Induction of phagocyte oxidase components during human myeloid differentiation: independent protein expression and discrepancy with the function.
Bioscience, biotechnology, and biochemistry 2001;65(11):2581-4.
2001: Hiroyuki Nunoi; T Yamazaki; Shiro Kanegasaki
Neutrophil cytoskeletal disease.
International journal of hematology 2001;74(2):119-24.
2001: Fuminari Ishibashi; Tomoyuki Mizukami; Shiro Kanegasaki; L Motoda; R Kakinuma; Fumio Endo; Hiroyuki Nunoi
Improved superoxide-generating ability by interferon gamma due to splicing pattern change of transcripts in neutrophils from patients with a splice site mutation in CYBB gene.
Blood 2001;98(2):436-41.
2001: A Yamauchi; L Yu; A J Pötgens; Futoshi Kuribayashi; Hiroyuki Nunoi; Shiro Kanegasaki; D Roos; H L Malech; M C Dinauer; Michio Nakamura
Location of the epitope for 7D5, a monoclonal antibody raised against human flavocytochrome b558, to the extracellular peptide portion of primate gp91phox.
Microbiology and immunology 2001;45(3):249-57.
2000: Fuminari Ishibashi; Hiroyuki Nunoi; Fumio Endo; I Matsuda; Shiro Kanegasaki
Statistical and mutational analysis of chronic granulomatous disease in Japan with special reference to gp91-phox and p22-phox deficiency.
Human genetics 2000;106(5):473-81.
1999: Toshio Kitamura; Naomi Tanaka; J Watanabe; Shiro Kanegasaki; Yasuaki Yamada; Koh Nakata
Idiopathic pulmonary alveolar proteinosis as an autoimmune disease with neutralizing antibody against granulocyte/macrophage colony-stimulating factor.
The Journal of experimental medicine 1999;190(6):875-80.
1999: Hiroyuki Nunoi; T Yamazaki; H Tsuchiya; Shigeaki Kato; H L Malech; I Matsuda; Shiro Kanegasaki
A heterozygous mutation of beta-actin associated with neutrophil dysfunction and recurrent infection.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8693-8.
1999: T Tsuchiya; Shinobu Imajoh-Ohmi; Hiroyuki Nunoi; Shiro Kanegasaki
Uncompetitive inhibition of superoxide generation by a synthetic peptide corresponding to a predicted NADPH binding site in gp91-phox, a component of the phagocyte respiratory oxidase.
Biochemical and biophysical research communications 1999;257(1):124-8.
1999: Naomi Tanaka; J Watanabe; Toshio Kitamura; Yasuaki Yamada; Shiro Kanegasaki; Koh Nakata
Lungs of patients with idiopathic pulmonary alveolar proteinosis express a factor which neutralizes granulocyte-macrophage colony stimulating factor.
FEBS letters 1999;442(2-3):246-50.
1998: M Iwata; Hiroyuki Nunoi; I Matsuda; Shiro Kanegasaki; Takashi Tsuruo; Yoshikazu Sugimoto
Drug-selected complete restoration of superoxide generation in Epstein-Barr virus-transformed B cells from p47phox-deficient chronic granulomatous disease patients by using a bicistronic retrovirus vector encoding a human multi-drug resistance gene (MDR1) and the p47phox gene.
Human genetics 1998;103(4):419-23.
1998: R Matsumoto; H Matsumoto; M Seki; M Hata; Y Asano; Shiro Kanegasaki; R L Stevens; M Hirashima
Human ecalectin, a variant of human galectin-9, is a novel eosinophil chemoattractant produced by T lymphocytes.
The Journal of biological chemistry 1998;273(27):16976-84.
1998: Hiroyuki Nunoi; Y Sugimoto; Shiro Kanegasaki
[Prospects for gene therapy for chronic granulomatous disease with gp91-phox deficiency].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1998;39(2):132.
1997: Yuki Nakajima; J Alvarez-Bravo; J Cho; Koichi J Homma; Shiro Kanegasaki; Shunji Natori
Chemotherapeutic activity of synthetic antimicrobial peptides: correlation between chemotherapeutic activity and neutrophil-activating activity.
FEBS letters 1997;415(1):64-6.
1997: M Y Park; Shinobu Imajoh-Ohmi; Hiroyuki Nunoi; Shiro Kanegasaki
Synthetic peptides corresponding to various hydrophilic regions of the large subunit of cytochrome b558 inhibit superoxide generation in a cell-free system from neutrophils.
Biochemical and biophysical research communications 1997;234(2):531-6.
1997: K Nakata; T Tozu; Y Hoshikawa; A Sakai; Naomi Tanaka; T Akashi; Shiro Kanegasaki
[Suppressive effect of clarithromycin on the production of verotoxin by E. coli O157].
Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1997;71(5):437-42.
1997: N N Faizunnessa; T Tsuchiya; Atsushi Kumatori; H Kurozumi; Shinobu Imajoh-Ohmi; Shiro Kanegasaki; M Nakamura
A 25-kb deletion in the 5' region of the cytochrome b558 heavy chain gene (CYBB) in a patient with X-linked chronic granulomatous disease.
Human genetics 1997;99(4):469-73.
1997: S Aoshima; Hiroyuki Nunoi; M Ushikubi; Shiro Kanegasaki; N Chonabayashi; S Kudo; T Sato
[Study of peripheral neutrophil functions of macrolide-resistant patients with DPB (diffuse panbronchitis) by using flow cytometry].
The Japanese journal of antibiotics 1997;50 Suppl A():75-7.
1997: E Wada; H Sakiyama; M Nakamura; Shiro Kanegasaki
Density dependent change of myristoylated proteins in C3H10T1/2 fibroblasts and their transformants.
Cell biochemistry and function 1997;15(1):19-26.
1996: M Aoshima; Hiroyuki Nunoi; M Shimazu; S Shimizu; O Tatsuzawa; Richard Kenney; Shiro Kanegasaki
Two-exon skipping due to a point mutation in p67-phox--deficient chronic granulomatous disease.
Blood 1996;88(5):1841-5.
1995: T Shinagawa; Hiroyuki Nunoi; Shigeaki Nonoyama; Shiro Kanegasaki
Induction of CD40 in promyelocytic HL60 cells cultured with retinoic acid and/or various cytokines.
Journal of biochemistry 1995;118(3):534-40.
1995: Hiroyuki Nunoi; M Iwata; S Tatsuzawa; Y Onoe; S Shimizu; Shiro Kanegasaki; I Matsuda
AG dinucleotide insertion in a patient with chronic granulomatous disease lacking cytosolic 67-kD protein.
Blood 1995;86(1):329-33.
1995: S Kobayashi; Shinobu Imajoh-Ohmi; F Kuribayashi; Hiroyuki Nunoi; M Nakamura; Shiro Kanegasaki
Characterization of the superoxide-generating system in human peripheral lymphocytes and lymphoid cell lines.
Journal of biochemistry 1995;117(4):758-65.
1994: M Y Park; Shinobu Imajoh-Ohmi; Hiroyuki Nunoi; Shiro Kanegasaki
Peptides corresponding to the region adjacent to His-94 in the small subunit of cytochrome b558 inhibit superoxide generation in a cell-free system from human neutrophils.
Biochemical and biophysical research communications 1994;204(2):924-9.
1994: H Kikuchi; T Fujinawa; F Kuribayashi; A Nakanishi; Shinobu Imajoh-Ohmi; M Goto; Shiro Kanegasaki
Induction of essential components of the superoxide generating system in human monoblastic leukemia U937 cells.
Journal of biochemistry 1994;116(4):742-6.
1994: M Iwata; Hiroyuki Nunoi; H Yamazaki; T Nakano; H Niwa; S Tsuruta; S Ohga; S Ohmi; Shiro Kanegasaki; I Matsuda
Homologous dinucleotide (GT or TG) deletion in Japanese patients with chronic granulomatous disease with p47-phox deficiency.
Biochemical and biophysical research communications 1994;199(3):1372-7.
1993: Hisako Sakiyama; M Yasukawa; M Nishijima; E Wada; Shiro Kanegasaki
Mechanisms of suppression of X-ray-induced transformation of 10T1/2 cells by lipopolysaccharide.
Journal of radiation research 1993;34(4):285-93.
1993: Shiro Kanegasaki
[Superoxide-generating system in leukocytes: its activation mechanism and significance].
Human cell 1993;6(4):245-52.
1993: M Shiota; S Mori; Shinobu Imajoh-Ohmi; M Nakamura; Shiro Kanegasaki; H Serizawa; T Izumo; T Uehara
Expression of cytochrome b558 on B cell- and CD 30 positive-lymphomas.
Pathology, research and practice 1993;189(9):985-91.
1993: Y Ono; S Kimura; Shinichi Oka; K Shimada; O Kunii; Shiro Kanegasaki
Low opsonic activity in sera from HIV-infected patients against Streptococcus pneumoniae.
Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1993;67(11):1136-7.
1993: T Jibu; Sachiko Koike; Koichi Ando; T Matsumoto; M Kimoto; Shiro Kanegasaki
Antimetastatic activity of lipopolysaccharide against a NK-resistant murine fibrosarcoma.
Clinical & experimental metastasis 1993;11(4):306-12.
1993: M Kimoto; Koichi Ando; Sachiko Koike; T Matsumoto; T Jibu; H Moriya; Shiro Kanegasaki
Significance of platelets in an antimetastatic activity of bacterial lipopolysaccharide.
Clinical & experimental metastasis 1993;11(3):285-92.
1993: H Kikuchi; S Imajoh-Ohmi; Shiro Kanegasaki
Novel antibodies specific for proteolyzed forms of protein kinase C: production of anti-peptide antibodies available for in situ analysis of intracellular limited proteolysis.
Biochimica et biophysica acta 1993;1162(1-2):171-6.
1993: T Tsuchiya; M Ueda; H Ochiai; Shinobu Imajoh-Ohmi; Shiro Kanegasaki
Erythropoietin 5'-flanking sequence-binding protein induced during hypoxia and cobalt exposure.
Journal of biochemistry 1993;113(3):395-400.
1993: I Ueno; M Hoshino; T Maitani; Shiro Kanegasaki; Yoshio Ueno
Luteoskyrin, an anthraquinoid hepatotoxin, and ascorbic acid generate hydroxyl radical in vitro in the presence of a trace amount of ferrous iron.
Free radical research communications 1993;19 Suppl 1():S95-100.
1992: A Nakanishi; Shinobu Imajoh-Ohmi; T Fujinawa; H Kikuchi; Shiro Kanegasaki
Direct evidence for interaction between COOH-terminal regions of cytochrome b558 subunits and cytosolic 47-kDa protein during activation of an O(2-)-generating system in neutrophils.
The Journal of biological chemistry 1992;267(27):19072-4.
1992: Shiro Kanegasaki
[Active oxygen generating system in immune cells].
Rinsho byori. The Japanese journal of clinical pathology 1992;40(4):392-6.
1992: T Tsuchiya; H Ochiai; Shinobu Imajoh-Ohmi; M Ueda; T Suda; M Nakamura; Shiro Kanegasaki
In vitro reconstitution of an erythropoietin gene transcription system using its 5'-flanking sequence and a nuclear extract from anemic kidney.
Biochemical and biophysical research communications 1992;182(1):137-43.
1992: Shinobu Imajoh-Ohmi; K Tokita; H Ochiai; M Nakamura; Shiro Kanegasaki
Topology of cytochrome b558 in neutrophil membrane analyzed by anti-peptide antibodies and proteolysis.
The Journal of biological chemistry 1992;267(1):180-4.
1991: T Jibu; Koichi Ando; T Matsumoto; Sachiko Koike; O Kobori; Y Morioka; Shiro Kanegasaki
Active components of intestinal bacteria for abdominal irradiation-induced inhibition of lung metastases.
Clinical & experimental metastasis 1991;9(6):529-40.
1991: I Ueno; S Fujii; H Ohya-Nishiguchi; T Iizuka; Shiro Kanegasaki
Characterization of neutrophil b-type cytochrome in situ by electron paramagnetic resonance spectroscopy.
FEBS letters 1991;281(1-2):130-2.
1990: S Kobayashi; Shinobu Imajoh-Ohmi; M Nakamura; Shiro Kanegasaki
Occurrence of cytochrome b558 in B-cell lineage of human lymphocytes.
Blood 1990;75(2):458-61.
1989: M Nakata; Taisuke Tomita; T Iizuka; Shiro Kanegasaki
Inhibitory effect of antibiotic cerulenin on the respiratory burst in phagocytes. II. Inhibition by cerulenin of intracellular calcium mobilization in human neutrophils.
The Journal of antibiotics 1989;42(7):1178-83.
1989: M Nakata; Taisuke Tomita; Shiro Kanegasaki
Inhibitory effect of antibiotic cerulenin on the respiratory burst in phagocytes. I. Effects of cerulenin on active oxygen-generation and lipid metabolism in phagocytes.
The Journal of antibiotics 1989;42(7):1171-7.
1989: I Ueno; M Kohno; K Mitsuta; Y Mizuta; Shiro Kanegasaki
Reevaluation of the spin-trapped adduct formed from 5,5-dimethyl-1-pyrroline-1-oxide during the respiratory burst in neutrophils.
Journal of biochemistry 1989;105(6):905-10.
1988: M Nakamura; S Kobayashi; S Sendo; T Koga; Shiro Kanegasaki
Deficiency of cytochrome b558 in chronic granulomatous disease demonstrated by monoclonal antibody 7D5.
Acta paediatrica Hungarica 1988;29(1-2):179-83.