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Hideo Kanoh

Research Profile

Chemicals & Drugs

Anatomy

Physiology

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Phosphorylation

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Cloning, Molecular

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Publications

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Masahiro Kai; Satoshi Yasuda; Shin-ichi Imai; Minoru Toyota; Hideo Kanoh; Fumio Sakane
Diacylglycerol kinase alpha enhances protein kinase Czeta-dependent phosphorylation at Ser311 of p65/RelA subunit of nuclear factor-kappaB.
Shin-Ichi Imai; Satoshi Yasuda; Masahiro Kai; Hideo Kanoh; Fumio Sakane
Diacylglycerol kinase delta associates with receptor for activated C kinase 1, RACK1.
Fumio Sakane; Shin-ichi Imai; Masahiro Kai; Satoshi Yasuda; Hideo Kanoh
Diacylglycerol kinases as emerging potential drug targets for a variety of diseases.

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All Publications

2009: Masahiro Kai; Satoshi Yasuda; Shin-ichi Imai; Minoru Toyota; Hideo Kanoh; Fumio Sakane
Diacylglycerol kinase alpha enhances protein kinase Czeta-dependent phosphorylation at Ser311 of p65/RelA subunit of nuclear factor-kappaB.
FEBS letters 2009;583(19):3265-8.
2009: Shin-Ichi Imai; Satoshi Yasuda; Masahiro Kai; Hideo Kanoh; Fumio Sakane
Diacylglycerol kinase delta associates with receptor for activated C kinase 1, RACK1.
Biochimica et biophysica acta 2009;1791(4):246-53.
2008: Fumio Sakane; Shin-ichi Imai; Masahiro Kai; Satoshi Yasuda; Hideo Kanoh
Diacylglycerol kinases as emerging potential drug targets for a variety of diseases.
Current drug targets 2008;9(8):626-40.
2008: Satoshi Yasuda; Masahiro Kai; Shin-ichi Imai; Hideo Kanoh; Fumio Sakane
Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase gamma with the Src homology 2 and C1 domains of beta2-chimaerin.
The Biochemical journal 2008;409(1):95-106.
2008: Akinori Kawakami; Fumio Sakane; Shin-ichi Imai; Satoshi Yasuda; Masahiro Kai; Hideo Kanoh; Hai-Ying Jin; Kuninori Hirosaki; Toshiharu Yamashita; David E Fisher; Kowichi Jimbow
Rab7 regulates maturation of melanosomal matrix protein gp100/Pmel17/Silv.
The Journal of investigative dermatology 2008;128(1):143-50.
2007: Masahiro Kai; Satoshi Yasuda; Shin-Ichi Imai; Hideo Kanoh; Fumio Sakane
Tyrosine phosphorylation of beta2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity.
Biochimica et biophysica acta 2007;1773(9):1407-15.
2007: Fumio Sakane; Shin-Ichi Imai; Masahiro Kai; Satoshi Yasuda; Hideo Kanoh
Diacylglycerol kinases: why so many of them?
Biochimica et biophysica acta 2007;1771(7):793-806.
2007: Kenji Yanagisawa; Satoshi Yasuda; Masahiro Kai; Shin-ichi Imai; Keiko Yamada; Toshiharu Yamashita; Kowichi Jimbow; Hideo Kanoh; Fumio Sakane
Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation.
Biochimica et biophysica acta 2007;1771(4):462-74.
2007: Satoshi Yasuda; Masahiro Kai; Shin-Ichi Imai; Hideo Kanoh; Fumio Sakane
Diacylglycerol kinase gamma interacts with and activates beta2-chimaerin, a Rac-specific GAP, in response to epidermal growth factor.
FEBS letters 2007;581(3):551-7.
2006: Masahiro Kai; Fumio Sakane; Yan-Jun Jia; Shin-Ichi Imai; Satoshi Yasuda; Hideo Kanoh
Lipid phosphate phosphatases 1 and 3 are localized in distinct lipid rafts.
Journal of biochemistry 2006;140(5):677-86.
2005: Shin-ichi Imai; Masahiro Kai; Satoshi Yasuda; Hideo Kanoh; Fumio Sakane
Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa.
The Journal of biological chemistry 2005;280(48):39870-81.
2004: Shin-Ichi Imai; Masahiro Kai; Keiko Yamada; Hideo Kanoh; Fumio Sakane
The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain.
The Biochemical journal 2004;382(Pt 3):957-66.
2004: Shuichi Tsushima; Masahiro Kai; Keiko Yamada; Shin-ichi Imai; Kiyohiro Houkin; Hideo Kanoh; Fumio Sakane
Diacylglycerol kinase gamma serves as an upstream suppressor of Rac1 and lamellipodium formation.
The Journal of biological chemistry 2004;279(27):28603-13.
2004: Asako Kamada; Hisao Nagaya; Taku Tamura; Masataka Kinjo; Hai-Ying Jin; Toshiharu Yamashita; Kowichi Jimbow; Hideo Kanoh; Ikuo Wada
Regulation of immature protein dynamics in the endoplasmic reticulum.
The Journal of biological chemistry 2004;279(20):21533-42.
2003: Yan-Jun Jia; Masahiro Kai; Ikuo Wada; Fumio Sakane; Hideo Kanoh
Differential localization of lipid phosphate phosphatases 1 and 3 to cell surface subdomains in polarized MDCK cells.
FEBS letters 2003;552(2-3):240-6.
2003: Tomohiro Murakami; Fumio Sakane; Shin-ichi Imai; Kiyohiro Houkin; Hideo Kanoh
Identification and characterization of two splice variants of human diacylglycerol kinase eta.
The Journal of biological chemistry 2003;278(36):34364-72.
2003: Keiko Yamada; Fumio Sakane; Shuichi Tsushima; Tomohiro Murakami; Shin ichi Imai; Hideo Kanoh
Regulatory role of diacylglycerol kinase gamma in macrophage differentiation of leukemia cells.
Biochemical and biophysical research communications 2003;305(1):101-7.
2002: Fumio Sakane; Shin-Ichi Imai; Keiko Yamada; Tomohiro Murakami; Shuichi Tsushima; Hideo Kanoh
Alternative splicing of the human diacylglycerol kinase delta gene generates two isoforms differing in their expression patterns and in regulatory functions.
The Journal of biological chemistry 2002;277(45):43519-26.
2002: Shin-ichi Imai; Fumio Sakane; Hideo Kanoh
Phorbol ester-regulated oligomerization of diacylglycerol kinase delta linked to its phosphorylation and translocation.
The Journal of biological chemistry 2002;277(38):35323-32.
2002: Hideo Kanoh; Keiko Yamada; Fumio Sakane
Diacylglycerol kinases: emerging downstream regulators in cell signaling systems.
Journal of biochemistry 2002;131(5):629-33.
2002: Hisao Nagaya; Ikuo Wada; Yan-Jun Jia; Hideo Kanoh
Diacylglycerol kinase delta suppresses ER-to-Golgi traffic via its SAM and PH domains.
Molecular biology of the cell 2002;13(1):302-16.
2000: T Ishikawa; Masahiro Kai; Ikuo Wada; Hideo Kanoh
Cell surface activities of the human type 2b phosphatidic acid phosphatase.
Journal of biochemistry 2000;127(4):645-51.
1999: Hideo Kanoh; Masahiro Kai; Ikuo Wada
[Phosphatidic acid phosphatase].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(8 Suppl):983-8.
1999: Hideo Kanoh; Masahiro Kai; Ikuo Wada
Molecular characterization of the type 2 phosphatidic acid phosphatase.
Chemistry and physics of lipids 1999;98(1-2):119-26.
1998: Ikuo Wada; Masahiro Kai; Hideo Kanoh
[Phosphatidic acid phosphatase (type 2), haloperoxidase family and germ cell migration].
Seikagaku. The Journal of Japanese Biochemical Society 1998;70(9):1185-8.
1997: Fumio Sakane; Hideo Kanoh
Molecules in focus: diacylglycerol kinase.
The international journal of biochemistry & cell biology 1997;29(10):1139-43.
1997: Masahiro Kai; Ikuo Wada; S i Imai; Fumio Sakane; Hideo Kanoh
Cloning and characterization of two human isozymes of Mg2+-independent phosphatidic acid phosphatase.
The Journal of biological chemistry 1997;272(39):24572-8.
1997: Hideo Kanoh; Masahiro Kai; Ikuo Wada
Phosphatidic acid phosphatase from mammalian tissues: discovery of channel-like proteins with unexpected functions.
Biochimica et biophysica acta 1997;1348(1-2):56-62.
1997: Ikuo Wada; Masahiro Kai; S Imai; Fumio Sakane; Hideo Kanoh
Promotion of transferrin folding by cyclic interactions with calnexin and calreticulin.
The EMBO journal 1997;16(17):5420-32.
1997: Keiko Yamada; Fumio Sakane; Norio Matsushima; Hideo Kanoh
EF-hand motifs of alpha, beta and gamma isoforms of diacylglycerol kinase bind calcium with different affinities and conformational changes.
The Biochemical journal 1997;321 ( Pt 1)():59-64.
1996: Ikuo Wada; Masahiro Kai; S Imai; Fumio Sakane; Hideo Kanoh
Translocation of diacylglycerol kinase alpha to the nuclear matrix of rat thymocytes and peripheral T-lymphocytes.
FEBS letters 1996;393(1):48-52.
1996: Hideo Kanoh; Masahiro Kai; Ikuo Wada
Molecular properties of enzymes involved in diacylglycerol and phosphatidate metabolism.
Journal of lipid mediators and cell signalling 1996;14(1-3):245-50.
1996: Fumio Sakane; Masahiro Kai; Ikuo Wada; S Imai; Hideo Kanoh
The C-terminal part of diacylglycerol kinase alpha lacking zinc fingers serves as a catalytic domain.
The Biochemical journal 1996;318 ( Pt 2)():583-90.
1996: Masahiro Kai; Ikuo Wada; S Imai; Fumio Sakane; Hideo Kanoh
Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes. Polymerase chain reaction amplification of mouse H2O2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphatase.
The Journal of biological chemistry 1996;271(31):18931-8.
1996: Fumio Sakane; S Imai; Masahiro Kai; Ikuo Wada; Hideo Kanoh
Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases.
The Journal of biological chemistry 1996;271(14):8394-401.
1995: Ikuo Wada; S Imai; Masahiro Kai; Fumio Sakane; Hideo Kanoh
Chaperone function of calreticulin when expressed in the endoplasmic reticulum as the membrane-anchored and soluble forms.
The Journal of biological chemistry 1995;270(35):20298-304.
1994: Masahiro Kai; Fumio Sakane; S Imai; Ikuo Wada; Hideo Kanoh
Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in human retina with a truncated and inactive enzyme expression in most other human cells.
The Journal of biological chemistry 1994;269(28):18492-8.