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Lothar Kanz

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Juliane S Stickel; Jörg-Peter Vollmer; Christine S Zürn; Meinrad Gawaz; Lothar Kanz; Frank Mayer; Axel Bauer
Ventricular thrombus and thrombocytopenia as first presentation of anaplastic thyroid carcinoma.
M Heni; Lothar Kanz; F Mayer; G Schnauder; B Besemer; M Guthoff; Maik Häntschel; H- U Häring; Stefan Wirths; W Vogel
[Endocrine abnormalities in a young patient with metastatic cancer - case 3/2013].
Stefanie Bugl; Julia-Stefanie Frick; Rupert Handgretinger; Lothar Kanz; Maya C André; Elke Malenke; Melanie Märklin; Martin R Müller; Markus P Radsak; Hans-Georg Rammensee; Hansjörg Schild; Pamela Stein; Tina Wiesner; Stefan Wirths; Hans-Georg Kopp
Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling.

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2013: Juliane S Stickel; Jörg-Peter Vollmer; Christine S Zürn; Meinrad Gawaz; Lothar Kanz; Frank Mayer; Axel Bauer
Ventricular thrombus and thrombocytopenia as first presentation of anaplastic thyroid carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(12):e194-6.
2013: M Heni; Lothar Kanz; F Mayer; G Schnauder; B Besemer; M Guthoff; Maik Häntschel; H- U Häring; Stefan Wirths; W Vogel
[Endocrine abnormalities in a young patient with metastatic cancer - case 3/2013].
Deutsche medizinische Wochenschrift (1946) 2013;138(17):908.
2013: Stefanie Bugl; Julia-Stefanie Frick; Rupert Handgretinger; Lothar Kanz; Maya C André; Elke Malenke; Melanie Märklin; Martin R Müller; Markus P Radsak; Hans-Georg Rammensee; Hansjörg Schild; Pamela Stein; Tina Wiesner; Stefan Wirths; Hans-Georg Kopp
Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling.
Blood 2013;121(5):723-33.
2013: Stefan Wirths; Hans-Jörg Bühring; Falko Fend; Claus Hann von Weyhern; Lothar Kanz; Torsten Kluba; Elke Malenke; Frank Mayer; Martin R Müller; Florian Nagl; Simone Rieger; Sabine Schleicher; Wichard Vogel; Hans-Georg Kopp
Shared cell surface marker expression in mesenchymal stem cells and adult sarcomas.
Stem cells translational medicine 2013;2(1):53-60.
2013: M Konantz; O S Kustikova; S Lehle; L Quintanilla-Martinez; O C Rothfuss; Helmut R Salih; K Schulze-Osthoff; H Wang; M C André; C Baum; M Ebinger; Frank Essmann; F Fend; M Grauer; S Grzywna; Rupert Handgretinger; Lothar Kanz; Claudia Lengerke
EVI-1 modulates leukemogenic potential and apoptosis sensitivity in human acute lymphoblastic leukemia.
Leukemia 2013;27(1):56-65.
2012: D Schneidawind; W Vogel; C Faul; F Fend; Marius Horger; Lothar Kanz; D Nann; Wolfgang A Bethge
Allogeneic hematopoietic cell transplantation in patients with acute myeloid leukemia and pulmonary mucormycosis.
Transplant infectious disease : an official journal of the Transplantation Society 2012;14(6):E166-72.
2012: Wolfgang A Bethge; Martin Bornhauser; H Baurmann; Helmut Dittmann; Christoph Faul; B Federmann; Lothar Kanz; Matthias Stelljes; Rudolf Trenschel; Wichard Vogel; S von Harsdorf; D Bunjes
Dose-escalated radioimmunotherapy as part of reduced intensity conditioning for allogeneic transplantation in patients with advanced high-grade non-Hodgkin lymphoma.
Bone marrow transplantation 2012;47(11):1397-402.
2012: Birgit Federmann; Rupert Handgretinger; Lothar Kanz; Lambros Kordelas; Christoph Meisner; Michael Schumm; Rainer Schwerdtfeger; Matthias Stelljes; Gernot Stuhler; Wichard Vogel; Dietrich W Beelen; Gerhard Behre; Martin Bornhauser; Maximilian Christopeit; Christoph Faul; Wolfgang A Bethge
Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: a phase II study.
Haematologica 2012;97(10):1523-31.
2012: Kavitha Sivasubramaniyan; Malgorzata Sobiesiak; Harald Abele; Wilhelm K Aicher; Flavianna Cerabona; Peter de Zwart; Christoph Faul; Roshanak Ghazanfari; Sabrina Grimm; Abhishek Harichandan; Lothar Kanz; Daniela Lehnen; Elisabeth Mortha; Neli Petkova; Hans-Jörg Bühring
Phenotypic and functional heterogeneity of human bone marrow- and amnion-derived MSC subsets.
Annals of the New York Academy of Sciences 2012;1266():94-106.
2012: Nils Heyne; Lothar Kanz; Katharina Oehrlein; Barbara Denecke; Martina Guthoff; Hans-Ulrich Häring; Katja C Weisel
Extracorporeal light chain elimination: high cut-off (HCO) hemodialysis parallel to chemotherapy allows for a high proportion of renal recovery in multiple myeloma patients with dialysis-dependent acute kidney injury.
Annals of hematology 2012;91(5):729-35.
2012: Adriana C Drost; Mirjam Funk; Lothar Kanz; Karoline Pia Norz; Gabriele Seitz; Xingkui Xue; Anne Zipfel; Andreas Boehmler; Robert Möhle
The G protein-coupled receptor CysLT1 mediates chemokine-like effects and prolongs survival in chronic lymphocytic leukemia.
Leukemia & lymphoma 2012;53(4):665-73.
2012: Joerg C Henes; Lothar Kanz; Gabriela Riemekasten; Marc Schmalzing; Wichard Vogel; Falko Fend; Ina Kötter
Optimization of autologous stem cell transplantation for systemic sclerosis -- a single-center longterm experience in 26 patients with severe organ manifestations.
The Journal of rheumatology 2012;39(2):269-75.
2012: Tilman Todenhöfer; Claus Hann von Weyhern; Stefan Wirths; Arnulf Stenzl; Stefan Heckl; Jörg Hennenlotter; Marius Horger; Lothar Kanz; Christian Schwentner
Severe paraneoplastic hypereosinophilia in metastatic renal cell carcinoma.
BMC urology 2012;12():7.
2012: Eric Schweikle; Tina Baessler; Lothar Kanz; Robert Möhle; Sedat Yildirim; Katja C Weisel
Osteoprotegerin positively regulates hematopoietic progenitor cells.
Current stem cell research & therapy 2012;7(1):72-7.
2011: Hans-Georg Kopp; K Krauss; Tanja Fehm; Lothar Kanz; Annette Staebler; Wichard Vogel; Jennifer Zahm; Frank Mayer
Symptomatic bone marrow involvement in breast cancer--clinical presentation, treatment, and prognosis: a single institution review of 22 cases.
Anticancer research 2011;31(11):4025-30.
2011: Felicitas Thol; Katharina Wagner; Claudia Winschel; Haiyang Yun; Frederik Damm; Walter Fiedler; Arnold Ganser; Gudrun Göhring; Gerhard Heil; Dieter Hoelzer; Lothar Kanz; Hartmut Kirchner; Jürgen Krauter; Michael Lübbert; Andrea Lüdeking; Michael Morgan; Brigitte Schlegelberger; Michael Heuser
Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(21):2889-96.
2011: Susanne M Rittig; Maik Haentschel; Katrin J Weimer; Annkristin Heine; Martin R Muller; Wolfram Brugger; Marius S Horger; Olga Maksimovic; Arnulf Stenzl; Ingmar Hoerr; Hans-Georg Rammensee; Tobias A W Holderried; Lothar Kanz; Steve Pascolo; Peter Brossart
Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(5):990-9.
2011: Frederik Damm; Ruud Delwel; Walter Fiedler; Kerstin Görlich; Anika Grosshennig; Iyas Hamwi; Gerhard Heil; Michael Heuser; Lothar Kanz; Jürgen Krauter; Bob Löwenberg; Michael Lübbert; Michael Morgan; Christoph Reuter; Ewa Surdziel; Felicitas Thol; Peter J M Valk; Katharina Wagner; Arnold Ganser
Integrative prognostic risk score in acute myeloid leukemia with normal karyotype.
Blood 2011;117(17):4561-8.
2011: Karsten Müssig; Harald Staiger; Konstantinos Kantartzis; Andreas Fritsche; Lothar Kanz; Hans-Ulrich Häring
Type 2 diabetes mellitus and risk of malignancy: is there a strategy to identify a subphenotype of patients with increased susceptibility to endogenous and exogenous hyperinsulinism?
Diabetic medicine : a journal of the British Diabetic Association 2011;28(3):276-86.
2011: J C Henes; Lothar Kanz; Ina Kötter
Rituximab and leflunomide for Wegener's granulomatosis: a long-term follow-up.
Rheumatology international 2011;31(3):425-6.
2011: Frederik Damm; Tina Oberacker; Felicitas Thol; Ewa Surdziel; Katharina Wagner; Anuhar Chaturvedi; Michael Morgan; Karoline Bomm; Gudrun Göhring; Michael Lübbert; Lothar Kanz; Walter Fiedler; Brigitte Schlegelberger; Gerhard Heil; Richard F Schlenk; Konstanze Döhner; Hartmut Döhner; Jürgen Krauter; Arnold Ganser; Michael Heuser
Prognostic importance of histone methyltransferase MLL5 expression in acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(6):682-9.
2011: Steffen Boettcher; Alexander Wacker; Klaus Moerike; Hans-Georg Kopp; Karl Jaschonek; Thomas Grobosch; Lothar Kanz; Helmut R Salih
Acquired coagulopathy caused by intoxication with the superwarfarin-type anticoagulant rodenticide flocoumafen.
European journal of haematology 2011;86(2):173-5.
2011: Claudia Lengerke; Tanja Fehm; Ralf Kurth; Hans Neubauer; Veit Scheble; Friederike Müller; Friederike Schneider; Karen Petersen; Diethelm Wallwiener; Lothar Kanz; Falko Fend; Sven Perner; Petra M Bareiss; Annette Staebler
Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma.
BMC cancer 2011;11():42.
2011: B Federmann; M Hägele; Matthias Pfeiffer; Stefan Wirths; Michael Schumm; Christoph Faul; Wichard Vogel; Rupert Handgretinger; Lothar Kanz; Wolfgang A Bethge
Immune reconstitution after haploidentical hematopoietic cell transplantation: impact of reduced intensity conditioning and CD3/CD19 depleted grafts.
Leukemia 2011;25(1):121-9.
2010: Joerg C Henes; Marius Horger; Ilhan Guenaydin; Lothar Kanz; Ina Kötter
Mixed response to tocilizumab for ankylosing spondylitis.
Annals of the rheumatic diseases 2010;69(12):2217-8.
2010: Hans-Georg Kopp; Stefan Wirths; Christoph Faul; Wolfgang A Bethge; Stefan Scheding; Wolfram Brugger; Lothar Kanz; Wichard Vogel
Long-term results after transplantation of CD34+ selected (CellPro) versus unselected peripheral blood progenitor cells (PBPC) from related allogeneic donors.
Journal of cancer research and clinical oncology 2010;136(12):1921-7.
2010: Eckhard Thiel; Agnieszka Korfel; Peter Martus; Lothar Kanz; Frank Griesinger; Michael Rauch; Alexander Röth; Bernd Hertenstein; Theda von Toll; Thomas Hundsberger; Hans-Günther Mergenthaler; Malte Leithäuser; Tobias Birnbaum; Lars Fischer; Kristoph Jahnke; Ulrich Herrlinger; Ludwig Plasswilm; Thomas Nägele; Torsten Pietsch; D D; Michael Weller
High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial.
The lancet oncology 2010;11(11):1036-47.
2010: Wolfgang A Bethge; Thoralf Lange; Christoph Meisner; Stephanie von Harsdorf; Martin Bornhaeuser; Birgit Federmann; Michael Stadler; Lutz Uharek; Matthias Stelljes; Stefan Knop; Gerald Wulf; Rudolf Trenschel; Vladan Vucinic; Helmut Dittmann; Christoph Faul; Wichard Vogel; Lothar Kanz; Donald Bunjes
Radioimmunotherapy with yttrium-90-ibritumomab tiuxetan as part of a reduced- intensity conditioning regimen for allogeneic hematopoietic cell transplantation in patients with advanced non-Hodgkin lymphoma: results of a phase 2 study.
Blood 2010;116(10):1795-802.
2010: Felicitas Thol; Frederik Damm; Katharina Wagner; Gudrun Göhring; Brigitte Schlegelberger; Dieter Hoelzer; Michael Lübbert; Wolfgang Heit; Lothar Kanz; Günter Schlimok; Aruna Raghavachar; Walter Fiedler; Hartmut Kirchner; Gerhard Heil; Michael Heuser; Jürgen Krauter; Arnold Ganser
Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia.
Blood 2010;116(4):614-6.
2010: Christina Pfannenberg; Philip Aschoff; Helmut Dittmann; Frank Mayer; Gerald Reischl; Claus Von Weyhern; Lothar Kanz; Claus D Claussen; Roland Bares; Joerg T Hartmann
PET/CT with 18F-FLT: does it improve the therapeutic management of metastatic germ cell tumors?
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(6):845-53.
2010: Katharina Wagner; Frederik Damm; Gudrun Göhring; Kerstin Görlich; Michael Heuser; Irina Schäfer; Oliver G Ottmann; Michael Lübbert; Wolfgang Heit; Lothar Kanz; Günter Schlimok; Aruna A Raghavachar; Walter Fiedler; Hartmut H Kirchner; Wolfram Brugger; Manuela Zucknick; Brigitte Schlegelberger; Gerhard Heil; Arnold Ganser; Jürgen Krauter
Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(14):2356-64.
2010: Joerg Christoph Henes; Joerg Schedel; Lothar Kanz; Ina Kötter
Rituximab and concomitant leflunomide for the treatment of rheumatoid arthritis.
Rheumatology international 2010;30(5):709-12.
2010: Frederik Damm; Michael Heuser; Michael Morgan; Haiyang Yun; Anika Grosshennig; Gudrun Göhring; Brigitte Schlegelberger; Konstanze Döhner; Oliver G Ottmann; Michael Lübbert; Wolfgang Heit; Lothar Kanz; Günter Schlimok; Aruna Raghavachar; Walter Fiedler; Hartmut Kirchner; Hartmut Döhner; Gerhard Heil; Arnold Ganser; Jürgen Krauter
Single nucleotide polymorphism in the mutational hotspot of WT1 predicts a favorable outcome in patients with cytogenetically normal acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(4):578-85.
2009: Claudia Lengerke; Matthias Grauer; Nina I Niebuhr; Tamara Riedt; Lothar Kanz; In-Hyun Park; George Q Daley
Hematopoietic development from human induced pluripotent stem cells.
Annals of the New York Academy of Sciences 2009;1176():219-27.
2009: Adriana C Drost; Sibylle Weng; Gerhard Feil; Jochen Schäfer; Simon Baumann; Lothar Kanz; Karl-Dietrich Sievert; Arnulf Stenzl; Robert Möhle
In vitro myogenic differentiation of human bone marrow-derived mesenchymal stem cells as a potential treatment for urethral sphincter muscle repair.
Annals of the New York Academy of Sciences 2009;1176():135-43.
2009: Katja C Weisel; John Dick; Willem E Fibbe; Lothar Kanz
International Symposium and Workshop on hematopoietic stem cells VII, University of Tübingen, Germany, September 18-20, 2008.
Annals of the New York Academy of Sciences 2009;1176():1-17.
2009: Andreas M Boehmler; Adriana Drost; Lena Jaggy; Gabriele Seitz; Tina Wiesner; Claudio Denzlinger; Lothar Kanz; Robert Möhle
The CysLT1 ligand leukotriene D4 supports alpha4beta1- and alpha5beta1-mediated adhesion and proliferation of CD34+ hematopoietic progenitor cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):6789-98.
2009: Tamara Riedt; Martin Ebinger; Helmut R Salih; Jürgen Tomiuk; Rupert Handgretinger; Lothar Kanz; Frank Grünebach; Claudia Lengerke
Aberrant expression of the homeobox gene CDX2 in pediatric acute lymphoblastic leukemia.
Blood 2009;113(17):4049-51.
2009: Hans-Georg Kopp; S Yildirim; Katja C Weisel; Lothar Kanz; Wichard Vogel
Contamination of autologous peripheral blood progenitor cell grafts predicts overall survival after high-dose chemotherapy in multiple myeloma.
Journal of cancer research and clinical oncology 2009;135(4):637-42.
2009: Marcus Schittenhelm; Christian Kollmannsberger; Karin Oechsle; Amy Harlow; Jason Morich; Friedemann Honecker; Raffael Kurek; Stephan Störkel; Lothar Kanz; Christopher L Corless; Kwok-Kin Wong; Carsten Bokemeyer; Michael C Heinrich
Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer.
Molecular cancer therapeutics 2009;8(3):481-9.
2009: Katja C Weisel; Sedat Yildirim; Eric Schweikle; Lothar Kanz; Robert Möhle
Regulation of FLT3 and its ligand in normal hematopoietic progenitor cells.
Annals of hematology 2009;88(3):203-11.
2009: Katja C Weisel; Malcolm A S Moore; Lothar Kanz; Robert Möhle
Extended in vitro expansion of adult, mobilized CD34+ cells without significant cell senescence using a stromal cell coculture system with single cytokine support.
Stem cells and development 2009;18(2):229-34.
2009: Venkata Lokesh Battula; Sabrina Treml; Petra Bareiß; Friederike Gieseke; Helene Roelofs; Peter de Zwart; Ingo Müller; Bernhard Schewe; Thomas Skutella; Willem E Fibbe; Lothar Kanz; Hans-Jörg Bühring
Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1.
Haematologica 2009;94(2):173-84.
2009: Katja C Weisel; F Bautz; Gabriele Seitz; Sedat Yildirim; Lothar Kanz; Robert Möhle
Modulation of CXC chemokine receptor expression and function in human neutrophils during aging in vitro suggests a role in their clearance from circulation.
Mediators of inflammation 2009;2009():790174.
2009: Jan Pintoffl; Ines Meisinger; Frank Mayer; Marius Horger; Claus von Weyhern; Lothar Kanz; Jörg Thomas Hartmann
Long-term disease stabilization during second-line gemcitabine in a refractory metastatic haemangioendothelioma.
Anti-cancer drugs 2009;20(1):73-4.
2009: Katja C Weisel; Michael Böckeler; Leonardo Bianchi; Luigi M Terracciano; Frank Mayer; Lothar Kanz
Development of rapid light-chain deposition disease in hepatic arteries with severe ischemic cholangitis in a multiple myeloma patient treated with melphalan, prednisone and lenalidomide.
International journal of hematology 2009;89(1):91-4.
2008: Jörg Thomas Hartmann; Lothar Kanz
Sunitinib and periodic hair depigmentation due to temporary c-KIT inhibition.
Archives of dermatology 2008;144(11):1525-6.
2008: Katja C Weisel; Eckhart Weidmann; Ioannis Anagnostopoulos; Lothar Kanz; Antonio Pezzutto; Marion Subklewe
Epstein-Barr virus-associated B-cell lymphoma secondary to FCD-C therapy in patients with peripheral T-cell lymphoma.
International journal of hematology 2008;88(4):434-40.
2008: J C Henes; M Müller; J Krieger; Bernd M Balletshofer; A C Pfannenberg; Lothar Kanz; Ina Kötter
[18F] FDG-PET/CT as a new and sensitive imaging method for the diagnosis of large vessel vasculitis.
Clinical and experimental rheumatology 2008;26(3 Suppl 49):S47-52.
2008: Marius Horger; P Pereira; Claus D Claussen; Lothar Kanz; Reinhard Vonthein; B Denecke; C Driessen
Hyperattenuating bone marrow abnormalities in myeloma patients using whole-body non-enhanced low-dose MDCT: correlation with haematological parameters.
The British journal of radiology 2008;81(965):386-96.
2008: Anna Sureda; Stephen Robinson; Carme Canals; Angelo M Carella; Marc A Boogaerts; Dolores Caballero; Ann E Hunter; Lothar Kanz; Shimon Slavin; Jan J Cornelissen; Martin Gramatzki; Dietger Niederwieser; Nigel H Russell; Norbert Schmitz
Reduced-intensity conditioning compared with conventional allogeneic stem-cell transplantation in relapsed or refractory Hodgkin's lymphoma: an analysis from the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(3):455-62.
2008: Wolfgang A Bethge; Christoph Faul; Martin Bornhäuser; Gernot Stuhler; Dietrich W Beelen; Peter Lang; Matthias Stelljes; Wichard Vogel; Matthias Hägele; Rupert Handgretinger; Lothar Kanz
Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: an update.
Blood cells, molecules & diseases 2008;40(1):13-9.
2007: Ina Kötter; Alexander Wacker; Silvia Koch; Jörg Henes; Constanze Richter; Andreas Engel; Ilhan Günaydin; Lothar Kanz
Anakinra in patients with treatment-resistant adult-onset Still's disease: four case reports with serial cytokine measurements and a review of the literature.
Seminars in arthritis and rheumatism 2007;37(3):189-97.
2007: Michael Haap; Baptist Gallwitz; Claus Thamer; Karsten Müssig; Hans-Ulrich Häring; Lothar Kanz; Jörg Thomas Hartmann
Symptomatic hypoglycemia during imatinib mesylate in a non-diabetic female patient with gastrointestinal stromal tumor.
Journal of endocrinological investigation 2007;30(8):688-92.
2007: Frank Mayer; Hermann Aebert; Maximilian Rudert; Alfred Königsrainer; Marius Horger; Lothar Kanz; D D; Gerhard Ziemer; Jörg Thomas Hartmann
Primary malignant sarcomas of the heart and great vessels in adult patients--a single-center experience.
The oncologist 2007;12(9):1134-42.
2007: Jörg Thomas Hartmann; Frank Mayer; Jan Schleicher; Marius Horger; Jens Huober; Ines Meisinger; Jan Pintoffl; Gabriele Käfer; Lothar Kanz; Viktor Grünwald
Bendamustine hydrochloride in patients with refractory soft tissue sarcoma: a noncomparative multicenter phase 2 study of the German sarcoma group (AIO-001).
Cancer 2007;110(4):861-6.
2007: Hans-Georg Kopp; Marius Horger; Christoph Faul; Jörg Thomas Hartmann; Lothar Kanz; Peter Lang; Wichard Vogel
Granulocyte colony-stimulating factor induced pulmonary hemorrhage in a healthy stem cell donor.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(21):3174-5.
2007: Robert Möhle; Lothar Kanz
Hematopoietic growth factors for hematopoietic stem cell mobilization and expansion.
Seminars in hematology 2007;44(3):193-202.
2007: Katja C Weisel; Willem E Fibbe; Lothar Kanz
Meeting summary: International Symposium and Workshop on Hematopoietic Stem Cells VI, University of Tübingen, Germany, September 14-16, 2006.
Experimental hematology 2007;35(7):1005-14.
2007: Katharina M Brauer; Daniela Werth; Karin von Schwarzenberg; Anita Bringmann; Lothar Kanz; Frank Grünebach; Peter Brossart
BCR-ABL activity is critical for the immunogenicity of chronic myelogenous leukemia cells.
Cancer research 2007;67(11):5489-97.
2007: Katja C Weisel; Sedat Yildirim; Eric Schweikle; Lothar Kanz; Robert Möhle
Effect of FLT3 inhibition on normal hematopoietic progenitor cells.
Annals of the New York Academy of Sciences 2007;1106():190-6.
2007: Hans-Jörg Bühring; Venkata Lokesh Battula; Sabrina Treml; Bernhard Schewe; Lothar Kanz; Wichard Vogel
Novel markers for the prospective isolation of human MSC.
Annals of the New York Academy of Sciences 2007;1106():262-71.
2007: Xingkui Xue; Zhen Cai; Guido Seitz; Lothar Kanz; Katja C Weisel; Robert Möhle
Differential effects of G protein coupled receptors on hematopoietic progenitor cell growth depend on their signaling capacities.
Annals of the New York Academy of Sciences 2007;1106():180-9.
2007: Jörg Thomas Hartmann; Jan Pintoffl; Salah-Eddin Al-Batran; Detlef Quietzsch; Ines Meisinger; Marius Horger; Oliver Nehls; Carsten Bokemeyer; Alfred Königsrainer; Elke Jäger; Lothar Kanz
Mitomycin C plus infusional 5-fluorouracil in platinum-refractory gastric adenocarcinoma: an extended multicenter phase II study.
Onkologie 2007;30(5):235-40.
2007: Marius Horger; Lothar Kanz; Barbara Denecke; Reinhard Vonthein; Philippe Pereira; Claus D Claussen; Christoph Driessen
The benefit of using whole-body, low-dose, nonenhanced, multidetector computed tomography for follow-up and therapy response monitoring in patients with multiple myeloma.
Cancer 2007;109(8):1617-26.
2007: Martin Schmidt-Hieber; Igor Wolfgang Blau; Rudolf Trenschel; R Andreesen; Gernot Stuhler; Hermann Einsele; Lothar Kanz; Ulrich Keilholz; Olga Marinets; Dietrich W Beelen; Axel A Fauser; Liisa Volin; T Ruutu; Lutz Uharek; Thomas Fietz; Wolfgang Knauf; Werner Hopfenmüller; Eckhard Thiel; M Freund; Jochen Casper
Reduced-toxicity conditioning with fludarabine and treosulfan prior to allogeneic stem cell transplantation in multiple myeloma.
Bone marrow transplantation 2007;39(7):389-96.
2007: Stefan Balabanov; Artur Gontarewicz; Patrick Ziegler; Ulrike Hartmann; Winfried Kammer; Mhairi Copland; Ute Brassat; Martin Priemer; Ilona Hauber; Thomas Wilhelm; Gerold Schwarz; Lothar Kanz; Carsten Bokemeyer; Joachim Hauber; Tessa L Holyoake; Alfred Nordheim; Tim H Brümmendorf
Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach.
Blood 2007;109(4):1701-11.
2006: Karin Oechsle; Martin R Müller; Jörg Thomas Hartmann; Lothar Kanz; Carsten Bokemeyer
Aprepitant as salvage therapy in patients with chemotherapy-induced nausea and emesis refractory to prophylaxis with 5-HT(3) antagonists and dexamethasone.
Onkologie 2006;29(12):557-61.
2006: Jörg Thomas Hartmann; Ines Meisinger; Stefan Kröber; Katja C Weisel; Karin Klingel; Lothar Kanz
Progressive bicytopenia due to persistent parvovirus B19 infection after immunochemotherapy with fludarabine/cyclophosphamide and rituximab for relapsed B cell lymphoma.
Haematologica 2006;91(12 Suppl):ECR49.
2006: Wolfgang A Bethge; Matthias Haegele; Christoph Faul; Peter Lang; Michael Schumm; Martin Bornhauser; Rupert Handgretinger; Lothar Kanz
Haploidentical allogeneic hematopoietic cell transplantation in adults with reduced-intensity conditioning and CD3/CD19 depletion: fast engraftment and low toxicity.
Experimental hematology 2006;34(12):1746-52.
2006: Stefan Knop; M Schupp; E Wardelmann; D Stueker; M S Horger; Lothar Kanz; Hermann Einsele; S M Kroeber
A new case of Carney triad: gastrointestinal stromal tumours and leiomyoma of the oesophagus do not show activating mutations of KIT and platelet-derived growth factor receptor alpha.
Journal of clinical pathology 2006;59(10):1097-9.
2006: Hans-Georg Kopp; Lothar Kanz; Jörg Thomas Hartmann
Complete remission of relapsing high-grade angiosarcoma with single-agent metronomic trofosfamide.
Anti-cancer drugs 2006;17(8):997-8.
2006: Barbara Wassmann; Heike Pfeifer; Nicola Goekbuget; Dietrich W Beelen; Joachim Beck; Matthias Stelljes; Martin Bornhäuser; Albrecht Reichle; Jolanta B Perz; Rainer Haas; Arnold Ganser; Mathias Schmid; Lothar Kanz; Georg Lenz; Martin Kaufmann; Anja Binckebanck; Patrick Brück; Regina Reutzel; Harald Gschaidmeier; Stefan Schwartz; Dieter Hoelzer; Oliver G Ottmann
Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL).
Blood 2006;108(5):1469-77.
2006: Jan Wierecky; Martin R Müller; Stefan Wirths; Edith Halder-Oehler; Daniela Dörfel; Susanne M Schmidt; Maik Häntschel; Wolfram Brugger; Stephen Schröder; Marius Horger; Lothar Kanz; Peter Brossart
Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients.
Cancer research 2006;66(11):5910-8.
2006: Christian Kollmannsberger; Marcus Schittenhelm; Friedemann Honecker; J Tillner; D Weber; Karin Oechsle; Lothar Kanz; Carsten Bokemeyer
A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(6):1007-13.
2006: Jörg Thomas Hartmann; Karin Oechsle; Jens Huober; Andreas Jakob; M Azemar; Marius Horger; Lothar Kanz; Carsten Bokemeyer
An open label, non-comparative phase II study of gemcitabine as salvage treatment for patients with pretreated adult type soft tissue sarcoma.
Investigational new drugs 2006;24(3):249-53.
2006: Gernot Stuhler; Stefan Knop; M S Topp; Stefan Kröber; Ulrike Ernemann; Ulrich Herrlinger; Hermann Einsele; Lothar Kanz; Holger Hebart
Intravenously administered rituximab induces remission of EBV associated non Hodgkin lymphoma confined to the brain in a patient after allogeneic stem cell transplantation.
Haematologica 2006;91(3):ECR01.
2006: Hans-Georg Kopp; Markus Kuczyk; Johannes Classen; Arnulf Stenzl; Lothar Kanz; Frank Mayer; D D; Jörg Thomas Hartmann
Advances in the treatment of testicular cancer.
Drugs 2006;66(5):641-59.
2005: Ina Kötter; Thomas Daikeler; CC Amberger; Alan Tyndall; Lothar Kanz
Autologous stem cell transplantation of treatment-resistant systemic vasculitis--a single center experience and review of the literature.
Clinical nephrology 2005;64(6):485-9.
2005: Ina Kötter; Thomas Daikeler; H Einsele; S Koch; L Lochmann; Lothar Kanz; J Löffler
Relapse of autoimmune diseases after autologous T cell depleted stem cell transplantation may be triggered by T cells recently emigrated from the thymus.
Annals of the rheumatic diseases 2005;64(12):1787-9.
2005: Wolfgang A Bethge; Marc Schmalzing; Gernot Stuhler; Ulrike Schumacher; Stefan Kröber; Marius Horger; Hermann Einsele; Lothar Kanz; Holger Hebart
Mucormycoses in patients with hematologic malignancies: an emerging fungal infection.
Haematologica 2005;90 Suppl():ECR22.
2005: Stefan Knop; Ulrich Herrlinger; Ulrike Ernemann; Lothar Kanz; Holger Hebart
Fludarabine may induce durable remission in patients with leptomeningeal involvement of chronic lymphocytic leukemia.
Leukemia & lymphoma 2005;46(11):1593-8.
2005: Ulrich Herrlinger; Holger Hebart; Lothar Kanz; Johannes Dichgans; Michael Weller
Relapse of primary CNS lymphoma after more than 10 years in complete remission.
Journal of neurology 2005;252(11):1409-10.
2005: Martin Sökler; Lothar Kanz
[Systemic mastocytosis].
Deutsche medizinische Wochenschrift (1946) 2005;Suppl 1():96.
2005: Claudia Lengerke; Stefan Wirths; Lothar Kanz; Holger Hebart; Edwin Kaiserling; Stefan M Krober; Marius Horger; Karsten Soennichsen
Unusual leukemia presentations. Case 1. Pulmonary chloroma preceded by leukemia cutis 7 years earlier.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(24):5837-9.
2005: Michael Haap; Ina Kötter; Marius Horger; Claus Thamer; Manfred Wehrmann; Hans-Ulrich Häring; Lothar Kanz; Jörg Thomas Hartmann
Disseminated epitheloid hemangioendothelioma mimicking symptoms of systemic vasculitis.
Onkologie 2005;28(8-9):429-32.
2005: Jörg Thomas Hartmann; Oliver Rick; Karin Oechsle; Markus Kuczyk; Thomas Gauler; Patrick Schöffski; Jan Schleicher; Frank Mayer; Reinhard Teichmann; Lothar Kanz; Carsten Bokemeyer
Role of postchemotherapy surgery in the management of patients with liver metastases from germ cell tumors.
Annals of surgery 2005;242(2):260-6.
2005: Kerol Bartolović; Stefan Balabanov; Birgit Berner; Hans-Jörg Bühring; Martina Komor; Sven Becker; Dieter Hoelzer; Lothar Kanz; Wolf-Karsten Hofmann; Tim H Brümmendorf
Clonal heterogeneity in growth kinetics of CD34+CD38- human cord blood cells in vitro is correlated with gene expression pattern and telomere length.
Stem cells (Dayton, Ohio) 2005;23(7):946-57.
2005: Stefan Balabanov; Kerol Bartolovic; Martina Komor; Lothar Kanz; Wolf-Karsten Hofmann; Tim H Brümmendorf
Gene expression profiling of normal hematopoietic progenitor cells under treatment with imatinib in vitro.
Leukemia 2005;19(8):1483-5.
2005: Christian Kollmannsberger; W Budach; M Stahl; Norbert Schleucher; Thomas Hehr; Hansjochen Wilke; Jan Schleicher; Udo Vanhoefer; Ekkehard C Jehle; Karin Oechsle; Tanja Trarbach; I Boehlke; Lothar Kanz; Jörg Thomas Hartmann; Carsten Bokemeyer
Adjuvant chemoradiation using 5-fluorouracil/folinic acid/cisplatin with or without paclitaxel and radiation in patients with completely resected high-risk gastric cancer: two cooperative phase II studies of the AIO/ARO/ACO.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(8):1326-33.
2005: Fabian Beier; Stefan Balabanov; Tom Buckley; Klaus Dietz; Ulrike Hartmann; Markus T Rojewski; Lothar Kanz; Hubert Schrezenmeier; Tim H Brümmendorf
Accelerated telomere shortening in glycosylphosphatidylinositol (GPI)-negative compared with GPI-positive granulocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) detected by proaerolysin flow-FISH.
Blood 2005;106(2):531-3.
2005: S Yildirim; Andreas M Boehmler; Lothar Kanz; Robert Möhle
Expansion of cord blood CD34+ hematopoietic progenitor cells in coculture with autologous umbilical vein endothelial cells (HUVEC) is superior to cytokine-supplemented liquid culture.
Bone marrow transplantation 2005;36(1):71-9.
2005: Stefan Balabanov; Silke Appel; Lothar Kanz; Peter Brossart; Tim H Brümmendorf
Effect of tyrosine kinase inhibition using imatinib on normal lymphohematopoietic cells.
Annals of the New York Academy of Sciences 2005;1044():168-77.
2005: Guido Seitz; Andreas M Boehmler; Lothar Kanz; Robert Möhle
The role of sphingosine 1-phosphate receptors in the trafficking of hematopoietic progenitor cells.
Annals of the New York Academy of Sciences 2005;1044():84-9.
2005: Ulrich Herrlinger; Wilhelm Küker; Martin Uhl; Hans-Peter Blaicher; Hans-Otto Karnath; Lothar Kanz; D D; Michael Weller
NOA-03 trial of high-dose methotrexate in primary central nervous system lymphoma: final report.
Annals of neurology 2005;57(6):843-7.
2005: Katja C Weisel; Tim H Brümmendorf; Donald Orlic; Willem E Fibbe; Lothar Kanz
Meeting summary: International Symposium and Workshop on Hematopoietic Stem Cells V, University of Tübingen, Germany, September 16-18, 2004.
Experimental hematology 2005;33(5):513-22.
2005: Ulrike Hartmann; Stefan Balabanov; Patrick Ziegler; Jörg Fellenberg; Heiko van der Kuip; Justus Duyster; Hans-Peter Lipp; Carsten Bokemeyer; Lothar Kanz; Tim H Brümmendorf
Telomere length and telomerase activity in the BCR-ABL-transformed murine Pro-B cell line BaF3 is unaffected by treatment with imatinib.
Experimental hematology 2005;33(5):542-9.
2005: Thomas Daikeler; C Erley; Martin Mohren; CC Amberger; H Einsele; Lothar Kanz; Ina Kötter
Fever and increasing cANCA titre after kidney and autologous stem cell transplantation for Wegener's granulomatosis.
Annals of the rheumatic diseases 2005;64(4):646-7.
2005: Jan Wierecky; Christian Kollmannsberger; I Boehlke; Markus Kuczyk; Jan Schleicher; Norbert Schleucher; Bernd Metzner; Lothar Kanz; Jörg Thomas Hartmann; Carsten Bokemeyer
Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer.
Journal of cancer research and clinical oncology 2005;131(4):255-60.
2005: Wichard Vogel; Hans-Georg Kopp; Lothar Kanz; Hermann Einsele
Myeloma cell contamination of peripheral blood stem-cell grafts can predict the outcome in multiple myeloma patients after high-dose chemotherapy and autologous stem-cell transplantation.
Journal of cancer research and clinical oncology 2005;131(4):214-8.
2005: Martin Sökler; Lothar Kanz
[Systemic mastocytosis].
Deutsche medizinische Wochenschrift (1946) 2005;130(9):474.
2005: Claudia Lengerke; T Brümmendorf; U Herrlinger; Marius Horger; Lothar Kanz; J T Hartmann
Transient respiratory failure possibly associated to imatinib.
Investigational new drugs 2005;23(2):137-8.
2005: Ulrich Herrlinger; Agnieszka Korfel; Holger Hebart; Uwe Schlegel; Ludwig Plasswilm; Gerald Illerhaus; Jürgen Finke; William Krüger; Michael Montemurro; Timo Wolf; Eckhart Thiel; D D; Michael Weller; Lothar Kanz
Meeting report: primary central nervous system lymphoma: standards of care and future perspectives.
Onkologie 2005;28(2):109-11.
2004: Volker L Reichardt; Peter Brossart; Lothar Kanz
Dendritic cells in vaccination therapies of human malignant disease.
Blood reviews 2004;18(4):235-43.
2004: Wolfram Brugger; J Hirsch; Frank Grünebach; R Repp; Peter Brossart; Wichard Vogel; H-G Kopp; M G Manz; M Bitzer; G Schlimok; M Kaufmann; Arnold Ganser; K Fehnle; Martin Gramatzki; Lothar Kanz
Rituximab consolidation after high-dose chemotherapy and autologous blood stem cell transplantation in follicular and mantle cell lymphoma: a prospective, multicenter phase II study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(11):1691-8.
2004: Stefan Knop; Bernhard M Dohmen; Lothar Kanz; Roland Bares; Hermann Einsele
153 Samarium-EDTMP in myeloablative dosage followed by a second autotransplantation in patients with relapsed multiple myeloma.
Haematologica 2004;89(9):ECR36.
2004: Carsten Bokemeyer; Christian Kollmannsberger; Sally P Stenning; Jörg Thomas Hartmann; Alan Horwich; C Clemm; Arthur Gerl; Christoph Meisner; C-P Rückerl; Hans-J Schmoll; Lothar Kanz; T Oliver
Metastatic seminoma treated with either single agent carboplatin or cisplatin-based combination chemotherapy: a pooled analysis of two randomised trials.
British journal of cancer 2004;91(4):683-7.
2004: Hans-Georg Kopp; Lothar Kanz; Jörg Thomas Hartmann
Hypersensitivity pneumonitis associated with the use of trofosfamide.
Anti-cancer drugs 2004;15(6):603-4.
2004: Takafumi Kimura; Andreas M Boehmler; Guido Seitz; Selim Kuçi; Tina Wiesner; Volker Brinkmann; Lothar Kanz; Robert Möhle
The sphingosine 1-phosphate receptor agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34+ progenitor cells.
Blood 2004;103(12):4478-86.
2004: Jörg Thomas Hartmann; Karin Oechsle; Elke Jäger; Hans-Edgar Reis; Cornelie Haag; Norbert Niederle; Hans-Joachim Wilke; Karl-Heinz Pflüger; Salah Al Batran; Thomas Büchele; Ralf-Dieter Hofheinz; Lothar Kanz; Carsten Bokemeyer
Prospective multicenter phase II study of irinotecan as third-line therapy in metastatic colorectal cancer and progression after bolus and infusional 5-fluorouracil.
Anti-cancer drugs 2004;15(5):473-7.
2004: Stefan Knop; Juergen Bux; Stefan M Kroeber; Peter Bader; Holger Hebart; Lothar Kanz; Hermann Einsele
Fatal immune-mediated pancytopenia and a TRALI-like syndrome associated with high titers of recipient-type antibodies against donor-derived peripheral blood cells after allogeneic bone marrow transplantation following dose reduced conditioning.
Haematologica 2004;89(5):ECR12.
2004: Stefan Scheding; Markus Bergmannn; Gisa Rathke; Wichard Vogel; Wolfram Brugger; Lothar Kanz
Additional transplantation of ex vivo generated megakaryocytic cells after high-dose chemotherapy.
Haematologica 2004;89(5):630-1.
2004: Martin Mohren; Thomas Daikeler; D Benz; Ilhan Günaydin; Lothar Kanz; Ina Kötter
Myeloablative immunosuppressive treatment with autologous haematopoietic stem cell transplantation in a patient with psoriatic arthropathy and monoclonal gammopathy of undetermined significance.
Annals of the rheumatic diseases 2004;63(4):466-7.
2004: Susanne M Schmidt; Kerstin Schag; Martin R Müller; Toni Weinschenk; Silke Appel; Oliver Schoor; Markus M Weck; Frank Grünebach; Lothar Kanz; Stefan Stevanovic; Hans-Georg Rammensee; Peter Brossart
Induction of adipophilin-specific cytotoxic T lymphocytes using a novel HLA-A2-binding peptide that mediates tumor cell lysis.
Cancer research 2004;64(3):1164-70.
2004: Stefan Knop; Andreas Jakob; Lothar Kanz; Holger Hebart; Roland Bares; Bernhard Dohmen
186Rhenium-labeled anti-CD20 antibody radioimmunotherapy followed by autologous peripheral blood stem cell transplantation in patients with relapsed or refractory non-Hodgkin lymphoma.
Blood 2004;103(3):1175.
2004: Silke Appel; Andreas M Boehmler; Frank Grünebach; Martin R Müller; Anette Rupf; Markus M Weck; Ulrike Hartmann; Volker L Reichardt; Lothar Kanz; Tim H Brümmendorf; Peter Brossart
Imatinib mesylate affects the development and function of dendritic cells generated from CD34+ peripheral blood progenitor cells.
Blood 2004;103(2):538-44.
2004: Kerol Bartolovic; Stefan Balabanov; Ulrike Hartmann; Martina Komor; Andreas M Boehmler; Hans-Jörg Bühring; Robert Möhle; Dieter Hoelzer; Lothar Kanz; Wolf-Karsten Hofmann; Tim H Brümmendorf
Inhibitory effect of imatinib on normal progenitor cells in vitro.
Blood 2004;103(2):523-9.
2004: Katja C Weisel; Wolfram Brugger; Stefan Kröber; Edwin Kaiserling; Lothar Kanz
Intravascular lymphoma - a rare cause of hemolytic anemia and neurologic disorders.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(5):444-6.
2004: Christian Kollmannsberger; Jörg Beyer; R Liersch; P Schoeffski; Bernd Metzner; Jörg Thomas Hartmann; Oliver Rick; K Stengele; K Hohloch; C Spott; Lothar Kanz; Carsten Bokemeyer
Combination chemotherapy with gemcitabine plus oxaliplatin in patients with intensively pretreated or refractory germ cell cancer: a study of the German Testicular Cancer Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(1):108-14.
2003: Jörg Thomas Hartmann; Karin Oechsle; Detlef Quietzsch; Axel Wein; Ralf-Dieter Hofheinz; Friedemann Honecker; O Nehls; Claus-Henning Köhne; G Käfer; Lothar Kanz; Carsten Bokemeyer
Protracted infusional 5-fluorouracil plus high-dose folinic acid combined with bolus mitomycin C in patients with gastrointestinal cancer: a phase I/II dose escalation study.
British journal of cancer 2003;89(11):2051-6.
2003: Jürgen Krauter; Kerstin Gorlich; Oliver G Ottmann; Michael Lubbert; Hartmut Dohner; Wolfgang Heit; Lothar Kanz; Arnold Ganser; Gerhard Heil
Prognostic value of minimal residual disease quantification by real-time reverse transcriptase polymerase chain reaction in patients with core binding factor leukemias.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(23):4413-22.
2003: Hans-J Schmoll; Christian Kollmannsberger; Bernd Metzner; Jörg Thomas Hartmann; Norbert Schleucher; Patrick Schöffski; Jan Schleicher; Oliver Rick; Jörg Beyer; Dieter K Hossfeld; Lothar Kanz; Wolfgang E Berdel; Reinhard Andreesen; Carsten Bokemeyer
Long-term results of first-line sequential high-dose etoposide, ifosfamide, and cisplatin chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(22):4083-91.
2003: Peter Reichardt; Karin Oechsle; Daniel Pink; Carsten Bokemeyer; F Schneller; Rolf Issels; Lothar Kanz; Jörg Thomas Hartmann
An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma.
Investigational new drugs 2003;21(4):481-6.
2003: Volker L Reichardt; Caterina Milazzo; Wolfram Brugger; Hermann Einsele; Lothar Kanz; Peter Brossart
Idiotype vaccination of multiple myeloma patients using monocyte-derived dendritic cells.
Haematologica 2003;88(10):1139-49.
2003: A Wiesmann; Peter Bader; Christoph Faul; M Schnaidt; Lothar Kanz; Hermann Einsele
Successful haematopoietic stem cell transplantation from a matched unrelated donor following three graft failures from HLA-mismatched related donors.
Bone marrow transplantation 2003;32(7):729-31.
2003: Hermann Einsele; M Bamberg; W Budach; H Schmidberger; C F Hess; B Wörmann; Christoph Meisner; Christian Straka; Holger Hebart; Lorenz Trümper; Nicolaus Kröger; Axel R Zander; Susanna Hegewisch-Becker; D K Hossfeld; H Schmidt; P Müller; Günter Schlimok; Bernd Hertenstein; D Peest; Bernd Metzner; Norbert Frickhofen; Lothar Kanz; W I Bensinger
A new conditioning regimen involving total marrow irradiation, busulfan and cyclophosphamide followed by autologous PBSCT in patients with advanced multiple myeloma.
Bone marrow transplantation 2003;32(6):593-9.
2003: Alexander Kugler; Gernot Stuhler; Peter Walden; Gerhard Zöller; Anke Zobywalski; Peter Brossart; Uwe Trefzer; Silke Ullrich; Claudia A Müller; Volker Becker; Andreas Gross; Bernhard Hemmerlein; Lothar Kanz; Gerhard A Müller; Rolf-Hermann Ringert
Retraction: Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids.
Nature medicine 2003;9(9):1221.
2003: A Wiesmann; Peter Bader; D D; Christoph Faul; Lothar Kanz; Hermann Einsele
Severe acute graft-versus-host disease after T-cell depleted allogeneic stem cell graft from a second donor caused by persisting T-cells from the first donor.
Bone marrow transplantation 2003;32(5):511-3.
2003: Martin R Müller; Frank Grünebach; Katrin Kayser; Wichard Vogel; Alessio Nencioni; Wolfram Brugger; Lothar Kanz; Peter Brossart
Expression of her-2/neu on acute lymphoblastic leukemias: implications for the development of immunotherapeutic approaches.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3448-53.
2003: Helmut R Salih; Holger Antropius; Friederike Gieseke; Stefan Zoltan Lutz; Lothar Kanz; Hans-Georg Rammensee; Alexander Steinle
Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia.
Blood 2003;102(4):1389-96.
2003: Stefan Scheding; Inci Ersöz; Ulrike Hartmann; Kerol Bartolvic; Stefan Balabanov; Abdulgabar Salama; Lothar Kanz; Tim H Brümmendorf
Peripheral blood cell telomere length measurements indicate that hematopoietic stem cell turnover is not significantly increased in whole blood and apheresis PLT donors.
Transfusion 2003;43(8):1089-95.
2003: Susanne M Schmidt; Kerstin Schag; Martin R Müller; Markus M Weck; Silke Appel; Lothar Kanz; Frank Grünebach; Peter Brossart
Survivin is a shared tumor-associated antigen expressed in a broad variety of malignancies and recognized by specific cytotoxic T cells.
Blood 2003;102(2):571-6.
2003: Carsten Bokemeyer; Norbert Schleucher; Bernd Metzner; M Thomas; Oliver Rick; Hans-J Schmoll; Christian Kollmannsberger; I Boehlke; Lothar Kanz; Jörg Thomas Hartmann
First-line sequential high-dose VIP chemotherapy with autologous transplantation for patients with primary mediastinal nonseminomatous germ cell tumours: a prospective trial.
British journal of cancer 2003;89(1):29-35.
2003: Tim H Brümmendorf; Donald Orlic; Willem E Fibbe; Saul J Sharkis; Lothar Kanz
Meeting summary: International Symposium and Workshop on Hematopoietic Stem Cells IV, University of Tübingen, Germany, September 19-21, 2002.
Experimental hematology 2003;31(6):475-82.
2003: Ulrich Herrlinger; Frank Schwärzler; Robert Beck; Wilhelm Küker; Holger Hebart; Lothar Kanz; Johannes Dichgans; Michael Weller
Progressive multifocal leukoencephalopathy: cidofovir therapy in three patients with underlying hematological disease.
Journal of neurology 2003;250(5):612-4.
2003: Christina Giesert; Anke Marxer; D Robert Sutherland; Andre C Schuh; Lothar Kanz; Hans-Jorg Buhring
Antibody W7C5 defines a CD109 epitope expressed on CD34+ and CD34- hematopoietic and mesenchymal stem cell subsets.
Annals of the New York Academy of Sciences 2003;996():227-30.
2003: Tim Conze; Reiner Lammers; Selim Kuci; Marwa Scherl-Mostageer; Norbert Schweifer; Lothar Kanz; Hans-Jorg Buhring
CDCP1 is a novel marker for hematopoietic stem cells.
Annals of the New York Academy of Sciences 2003;996():222-6.
2003: Robert Mohle; Andreas M Boehmler; Claudio Denzlinger; Lothar Kanz
Nonpeptide mediators in the hematopoietic microenvironment.
Annals of the New York Academy of Sciences 2003;996():61-6.
2003: Tim H Brummendorf; Inci Ersoz; Ulrike Hartmann; Stefan Balabanov; Holger Wolke; Peter Paschka; Tanja Lahaye; Birgit Berner; Kerol Bartolovic; Sebastian Kreil; Ute Berger; Harald Gschaidmeier; Carsten Bokemeyer; Rüdiger Hehlmann; Klaus Dietz; Peter M Lansdorp; Lothar Kanz; Andreas Hochhaus
Normalization of previously shortened telomere length under treatment with imatinib argues against a preexisting telomere length deficit in normal hematopoietic stem cells from patients with chronic myeloid leukemia.
Annals of the New York Academy of Sciences 2003;996():26-38.
2003: Hermann Einsele; Hans-Jörg Schäfer; Holger Hebart; Peter Bader; Christoph Meisner; Ludwig Plasswilm; Peter Liebisch; D D; Christoph Faul; Lothar Kanz
Follow-up of patients with progressive multiple myeloma undergoing allografts after reduced-intensity conditioning.
British journal of haematology 2003;121(3):411-8.
2003: Christian Kollmannsberger; Norbert Schleucher; Oliver Rick; Bernd Metzner; Jörg Thomas Hartmann; Patrick Schöffski; Jörg Beyer; Jochen Casper; M Sosada; Hans-J Schmoll; I Böhlke; Christoph Meisner; Lothar Kanz; Carsten Bokemeyer
Analysis of salvage treatments for germ cell cancer patients who have relapsed after primary high-dose chemotherapy plus autologous stem cell support.
European journal of cancer (Oxford, England : 1990) 2003;39(6):775-82.
2003: Jörg Thomas Hartmann; Karin Oechsle; Frank Mayer; Lothar Kanz; Carsten Bokemeyer
Phase II trial of trofosfamide in patients with advanced pretreated soft tissue sarcomas.
Anticancer research 2003;23(2C):1899-901.
2003: Wichard Vogel; Frank Grünebach; Conrad A Messam; Lothar Kanz; Wolfram Brugger; Hans-Jörg Bühring
Heterogeneity among human bone marrow-derived mesenchymal stem cells and neural progenitor cells.
Haematologica 2003;88(2):126-33.
2003: Michaela Treusch; Nicole Stübiger; Reinhard Vonthein; Manuela Baur; Silvia Koch; Ilhan Günaydin; Lothar Kanz; Manfred Zierhut; Ina Kötter
Influence of interferon-alpha on lymphocyte subpopulations in Behçet's disease.
Advances in experimental medicine and biology 2003;528():533-5.
2003: Ina Kötter; Manfred Zierhut; Anja Katrin Eckstein; Reinhard Vonthein; Thomas Ness; Ilhan Günaydin; Bodo Grimbacher; Sabine Blaschke; Hans-Hartmut Peter; Lothar Kanz; Nicole Stübiger
Human recombinant interferon-alpha2a (rhIFN alpha2a) for the treatment of Behçet's disease with sight-threatening retinal vasculitis.
Advances in experimental medicine and biology 2003;528():521-3.
2003: Ina Kötter; Ilhan Günaydin; Michaela Treusch; Manfred Zierhut; Lothar Kanz; Nicole Stübiger
The use of interferon-alpha in Behçet's disease--review of the literature and possible mechanisms of action.
Advances in experimental medicine and biology 2003;528():503-9.
2003: Ina Kötter; Reinhard Vonthein; Ilhan Günaydin; Claudia Müller; Lothar Kanz; Manfred Zierhut; Nicole Stübiger
Behçet's disease in patients of German and Turkish origin--a comparative study.
Advances in experimental medicine and biology 2003;528():53-8.
2003: Carsten Bokemeyer; Jörg Thomas Hartmann; Sophie D Fossa; Jean Pierre Droz; Hans-J Schmol; Alan Horwich; Arthur Gerl; Jörg Beyer; Jörg Pont; Lothar Kanz; Craig Nichols; Lawrence Einhorn
Extragonadal germ cell tumors: relation to testicular neoplasia and management options.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):49-59; discussion 59-63.
2003: Andreas M Boehmler; Claudio Denzlinger; Lothar Kanz; Robert Möhle
Potential role of cysteinyl leukotrienes in trafficking and survival of hematopoietic progenitor cells.
Advances in experimental medicine and biology 2003;525():25-8.
2003: Tim H Brümmendorf; Inci Ersöz; Ulrike Hartmann; Kerol Bartolovic; Stefan Balabanov; Alexandra Wahl; Peter Paschka; Sebastian Kreil; Tanja Lahaye; Ute Berger; Harald Gschaidmeier; Carsten Bokemeyer; Rüdiger Hehlmann; Klaus Dietz; Peter M Lansdorp; Lothar Kanz; Andreas Hochhaus
Telomere length in peripheral blood granulocytes reflects response to treatment with imatinib in patients with chronic myeloid leukemia.
Blood 2003;101(1):375-6.
2002: Carsten Bokemeyer; Karin Oechsle; Jörg Thomas Hartmann; Patrick Schöffski; Norbert Schleucher; Bernd Metzner; Jan Schleicher; Lothar Kanz
Treatment-induced anaemia and its potential clinical impact in patients receiving sequential high dose chemotherapy for metastatic testicular cancer.
British journal of cancer 2002;87(10):1066-71.
2002: Carsten Bokemeyer; Lothar Kanz
[Allogeneic hematopoetic cell transplantation in patients with solid tumors - Contra].
Deutsche medizinische Wochenschrift (1946) 2002;127(42):2215.
2002: Anne Wiesmann; Robert Weissert; Lothar Kanz; Hermann Einsele
Long-term follow-up on a patient with incomplete POEMS syndrome undergoing high-dose therapy and autologous blood stem cell transplantation.
Blood 2002;100(7):2679-80.
2002: Christian Kollmannsberger; Oliver Rick; H Klaproth; T Kubin; H G Sayer; M Hentrich; M Welslau; Frank Mayer; Markus Kuczyk; C Spott; Lothar Kanz; Carsten Bokemeyer
Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group.
British journal of cancer 2002;87(7):729-32.
2002: Ludwig Plasswilm; Ulrich Herrlinger; Agnieszka Korfel; Michael Weller; Wilhelm Küker; Lothar Kanz; E Thiel; D D
Primary central nervous system (CNS) lymphoma in immunocompetent patients.
Annals of hematology 2002;81(8):415-23.
2002: Christian Kollmannsberger; Frank Mayer; Harald Pressler; S Koch; Lothar Kanz; J W Oosterhuis; Leendert H J Looijenga; Carsten Bokemeyer
Absence of c-KIT and members of the epidermal growth factor receptor family in refractory germ cell cancer.
Cancer 2002;95(2):301-8.
2002: Jörg Thomas Hartmann; Craig Nichols; Jean Pierre Droz; Alan Horwich; Arthur Gerl; Sophie D Fossa; Jörg Beyer; Jörg Pont; Lothar Kanz; Lawrence Einhorn; Carsten Bokemeyer
Prognostic variables for response and outcome in patients with extragonadal germ-cell tumors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13(7):1017-28.
2002: Wichard Vogel; Hans-Georg Kopp; Lothar Kanz; Hermann Einsele
Correlations between hematopoietic progenitor cell counts as measured by Sysmex and CD34+ cell harvest yields following mobilization with different regimens.
Journal of cancer research and clinical oncology 2002;128(7):380-4.
2002: Friedemann Honecker; Christian Kollmannsberger; Detlef Quietzsch; Caroline Haag; M Schroeder; C Spott; Jörg Thomas Hartmann; W Baronius; V Hempel; Lothar Kanz; Carsten Bokemeyer
Phase II study of weekly paclitaxel plus 24-h continuous infusion 5-fluorouracil, folinic acid and 3-weekly cisplatin for the treatment of patients with advanced gastric cancer.
Anti-cancer drugs 2002;13(5):497-503.
2002: Hermann Einsele; Eddy Roosnek; Nathalie Rufer; Christian Sinzger; Susanne Riegler; Jürgen Löffler; Ulrich Grigoleit; Arnaud Moris; Hans-Georg Rammensee; Lothar Kanz; Annette Kleihauer; Friederike Frank; Gerhard Jahn; Holger Hebart
Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy.
Blood 2002;99(11):3916-22.
2002: Holger Hebart; Senay Daginik; Stefan Stevanovic; Ulrich Grigoleit; Andrea Dobler; Manuela Baur; Georg Rauser; Christian Sinzger; Gerhard Jahn; Juergen Loeffler; Lothar Kanz; Hans-Georg Rammensee; Hermann Einsele
Sensitive detection of human cytomegalovirus peptide-specific cytotoxic T-lymphocyte responses by interferon-gamma-enzyme-linked immunospot assay and flow cytometry in healthy individuals and in patients after allogeneic stem cell transplantation.
Blood 2002;99(10):3830-7.
2002: Frank Mayer; Jörg Thomas Hartmann; Joachim von Pawel; J Beck; M Schroeder; I Boehlke; Lothar Kanz; Carsten Bokemeyer
A phase I study of oral uracil-ftorafur plus folinic acid in combination with weekly paclitaxel in patients with solid tumors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13(5):755-9.
2002: Christian Kollmannsberger; Karin Oechsle; Bernhard M Dohmen; Anna C Pfannenberg; Roland Bares; Claus D Claussen; Lothar Kanz; Carsten Bokemeyer
Prospective comparison of [18F]fluorodeoxyglucose positron emission tomography with conventional assessment by computed tomography scans and serum tumor markers for the evaluation of residual masses in patients with nonseminomatous germ cell carcinoma.
Cancer 2002;94(9):2353-62.
2002: Christian Kollmannsberger; Oliver Rick; Hans Günter Derigs; Norbert Schleucher; Patrick Schöffski; Jörg Beyer; R Schoch; H G Sayer; Arthur Gerl; Markus Kuczyk; C Spott; Lothar Kanz; Carsten Bokemeyer
Activity of oxaliplatin in patients with relapsed or cisplatin-refractory germ cell cancer: a study of the German Testicular Cancer Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(8):2031-7.
2002: Andreas Jakob; Carsten Bokemeyer; Stefan Knop; M Schupp; Frank Mayer; Lothar Kanz
Capecitabine in patients with breast cancer relapsing after high-dose chemotherapy plus autologous peripheral stem cell transplantation--a phase II study.
Anti-cancer drugs 2002;13(4):405-10.
2002: Carsten Bokemeyer; Craig Nichols; Jean Pierre Droz; Hans-J Schmoll; Alan Horwich; Arthur Gerl; Sophie D Fossa; Jörg Beyer; Jörg Pont; Lothar Kanz; Lawrence Einhorn; Jörg Thomas Hartmann
Extragonadal germ cell tumors of the mediastinum and retroperitoneum: results from an international analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(7):1864-73.
2002: Markus G Manz; Christoph Berger; Hans-Peter Horny; Robert Beck; Wolfram Brugger; Richard Viebahn; Lothar Kanz; Hans Knecht
Sustained remission of an extensive monoclonal, Epstein-Barr virus-associated diffuse large B cell lymphoma in a kidney-pancreas transplant recipient.
Transplantation 2002;73(6):995-7.
2002: Stefan Scheding; Markus Bergmann; Akihiro Shimosaka; Philipp Wolff; Christoph Driessen; Gisa Rathke; Karl Jaschonek; Wolfram Brugger; Lothar Kanz
Human plasma thrombopoietin levels are regulated by binding to platelet thrombopoietin receptors in vivo.
Transfusion 2002;42(3):321-7.
2002: Carsten Bokemeyer; Christian Kollmannsberger; Karin Oechsle; Bernhard M Dohmen; Anna C Pfannenberg; Claus D Claussen; Roland Bares; Lothar Kanz
Early prediction of treatment response to high-dose salvage chemotherapy in patients with relapsed germ cell cancer using [(18)F]FDG PET.
British journal of cancer 2002;86(4):506-11.
2002: Ulrich Herrlinger; Martin Schabet; Wolfram Brugger; Rolf-Dieter Kortmann; Wilhelm Küker; Martina Deckert; Corinna Engel; Hans-Jürgen Schmeck-Lindenau; Hans-Günther Mergenthaler; Peter Krauseneck; Christian Benöhr; Christoph Meisner; Otmar D Wiestler; Johannes Dichgans; Lothar Kanz; D D; Michael Weller
German Cancer Society Neuro-Oncology Working Group NOA-03 multicenter trial of single-agent high-dose methotrexate for primary central nervous system lymphoma.
Annals of neurology 2002;51(2):247-52.
2002: Karl S Lang; Benjamin Roll; Svetlana Myssina; Marcus Schittenhelm; Hans-Gerhard Scheel-Walter; Lothar Kanz; Jasmin Fritz; Florian Lang; Stephan M Huber; Thomas Wieder
Enhanced erythrocyte apoptosis in sickle cell anemia, thalassemia and glucose-6-phosphate dehydrogenase deficiency.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2002;12(5-6):365-72.
2001: R Stilz; Frank Grünebach; Peter Bader; W Vogel; Lothar Kanz; Wolfram Brugger; Stefan Scheding
Ex vivo expansion of normal progenitor cells from acute myeloid leukemia cell-contaminated CD34+ peripheral blood progenitor cells after mafosfamide purging.
Journal of hematotherapy & stem cell research 2001;10(6):777-85.
2001: Jörg Thomas Hartmann; Sophie D Fossa; Craig Nichols; Jean Pierre Droz; Alan Horwich; Arthur Gerl; Jörg Beyer; Jörg Pont; Karim Fizazi; H Hecker; Lothar Kanz; Lawrence Einhorn; Carsten Bokemeyer
Incidence of metachronous testicular cancer in patients with extragonadal germ cell tumors.
Journal of the National Cancer Institute 2001;93(22):1733-8.
2001: Peter Brossart; Stefan Wirths; Wolfram Brugger; Lothar Kanz
Dendritic cells in cancer vaccines.
Experimental hematology 2001;29(11):1247-55.
2001: Peter Brossart; A Schneider; P Dill; T Schammann; Frank Grünebach; Stefan Wirths; Lothar Kanz; Hans-Jörg Bühring; Wolfram Brugger
The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes.
Cancer research 2001;61(18):6846-50.
2001: H Schäfer; C Berger; Christian Aepinus; Holger Hebart; Robert Beck; Edwin Kaiserling; Lothar Kanz; Hermann Einsele; H Knecht
Molecular pathogenesis of Epstein-Barr virus associated posttransplant lymphomas: new insights through latent membrane protein 1 fingerprinting.
Transplantation 2001;72(3):492-6.
2001: Tim H Brümmendorf; Donald Orlic; Saul J Sharkis; Lothar Kanz
Meeting summary: International Symposium and Workshop on Hematopoietic Stem Cells III, University of Tübingen, Germany, September 14-16, 2000.
Experimental hematology 2001;29(7):797-802.
2001: Carsten Bokemeyer; Ad J M Gillis; K Pompe; Frank Mayer; Bernd Metzner; Norbert Schleucher; Jan Schleicher; G Pflugrad-Jauch; J W Oosterhuis; Lothar Kanz; Leendert H J Looijenga
Clinical impact of germ cell tumor cells in apheresis products of patients receiving high-dose chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(12):3029-36.
2001: Wolfram Brugger; A Schneider; T Schammann; P Dill; Frank Grünebach; Hans-Jörg Bühring; Lothar Kanz; Peter Brossart
Dendritic cell-based vaccines in patients with hematological malignancies.
Annals of the New York Academy of Sciences 2001;938():359-62; discussion 362-3.
2001: Robert Möhle; F Bautz; Claudio Denzlinger; Lothar Kanz
Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors.
Annals of the New York Academy of Sciences 2001;938():26-34; discussion 34-5.
2001: Christina Giesert; Graça Almeida-Porada; A Scheffold; Lothar Kanz; Esmail D Zanjani; Hans-Jörg Bühring
The monoclonal antibody W7C5 defines a novel surface antigen on hematopoietic stem cells.
Annals of the New York Academy of Sciences 2001;938():175-83.
2001: F Bautz; Claudio Denzlinger; Lothar Kanz; Robert Möhle
Chemotaxis and transendothelial migration of CD34(+) hematopoietic progenitor cells induced by the inflammatory mediator leukotriene D4 are mediated by the 7-transmembrane receptor CysLT1.
Blood 2001;97(11):3433-40.
2001: Hans-Jörg Bühring; M Seiffert; Christina Giesert; Anke Marxer; Lothar Kanz; Peter Valent; K Sano
The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3.
Blood 2001;97(10):3303-5.
2001: M Seiffert; Peter Brossart; C Cant; M Cella; Marco COLONna; Wolfram Brugger; Lothar Kanz; A Ullrich; Hans-Jörg Bühring
Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells.
Blood 2001;97(9):2741-9.
2001: Christian Kollmannsberger; Frank Mayer; Markus Kuczyk; Lothar Kanz; Carsten Bokemeyer
Treatment of patients with metastatic germ cell tumors relapsing after high-dose chemotherapy.
World journal of urology 2001;19(2):120-5.
2001: Annette Kleihauer; Ulrich Grigoleit; Holger Hebart; Arnaud Moris; Peter Brossart; A Muhm; Stefan Stevanovic; Hans-Georg Rammensee; Christian Sinzger; Susanne Riegler; Gerhard Jahn; Lothar Kanz; Hermann Einsele
Ex vivo generation of human cytomegalovirus-specific cytotoxic T cells by peptide-pulsed dendritic cells.
British journal of haematology 2001;113(1):231-9.
2001: M Manz; Reimer Riessen; L Poll; Bernhard M Dohmen; E Kaiserling; W Krück; M Laniado; Lothar Kanz; Claudio Denzlinger
High-grade lymphoma mimicking bone crisis in Gaucher's disease.
British journal of haematology 2001;113(1):191-3.
2001: Holger Hebart; W Brugger; Ulrich Grigoleit; B Gscheidle; Juergen Loeffler; H Schäfer; Lothar Kanz; Hermann Einsele; Christian Sinzger
Risk for cytomegalovirus disease in patients receiving polymerase chain reaction-based preemptive antiviral therapy after allogeneic stem cell transplantation depends on transplantation modality.
Blood 2001;97(7):2183-5.
2001: Carsten Bokemeyer; Jean Pierre Droz; Alan Horwich; Arthur Gerl; Sophie D Fossa; Jörg Beyer; Jörg Pont; Hans-J Schmoll; Lothar Kanz; Lawrence Einhorn; Craig Nichols; Jörg Thomas Hartmann
Extragonadal seminoma: an international multicenter analysis of prognostic factors and long term treatment outcome.
Cancer 2001;91(7):1394-401.
2001: Jörg Thomas Hartmann; Lawrence Einhorn; Craig Nichols; Jean Pierre Droz; Alan Horwich; Arthur Gerl; Sophie D Fossa; Jörg Beyer; Jörg Pont; Hans-J Schmoll; Lothar Kanz; Carsten Bokemeyer
Second-line chemotherapy in patients with relapsed extragonadal nonseminomatous germ cell tumors: results of an international multicenter analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(6):1641-8.
2001: Jörg Thomas Hartmann; A von Vangerow; Lüder M Fels; Stefan Knop; Hilmar Stolte; Lothar Kanz; Carsten Bokemeyer
A randomized trial of amifostine in patients with high-dose VIC chemotherapy plus autologous blood stem cell transplantation.
British journal of cancer 2001;84(3):313-20.
2001: Ulrich Herrlinger; Martin Schabet; Wolfram Brugger; Rolf-Dieter Kortmann; Lothar Kanz; D D; Johannes Dichgans; Michael Weller
Primary central nervous system lymphoma 1991-1997: outcome and late adverse effects after combined modality treatment.
Cancer 2001;91(1):130-5.
2001: Oliver Rick; Carsten Bokemeyer; Jörg Beyer; Jörg Thomas Hartmann; Nimrod Schwella; Dorothea Kingreen; S Neureither; Bernd Metzner; Jochen Casper; Hannes Wandt; F Hartmann; Hans-J Schmoll; Günter Derigs; Arthur Gerl; Wolfgang E Berdel; Lothar Kanz; Wolfgang Siegert
Salvage treatment with paclitaxel, ifosfamide, and cisplatin plus high-dose carboplatin, etoposide, and thiotepa followed by autologous stem-cell rescue in patients with relapsed or refractory germ cell cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(1):81-8.
2001: Ina Kötter; Christian Aepinus; F Graepler; V Gärtner; Anja Katrin Eckstein; Nicole Stübiger; Bernd A Kaskas; Manfred Zierhut; Burkhard D Bültmann; R Kandolf; Lothar Kanz
HHV8 associated Kaposi's sarcoma during triple immunosuppressive treatment with cyclosporin A, azathioprine, and prednisolone for ocular Behçet's disease and complete remission of both disorders with interferon alpha.
Annals of the rheumatic diseases 2001;60(1):83-6.
2000: Holger Hebart; Jürgen Löffler; H Reitze; A Engel; Ulrike Schumacher; Thomas Klingebiel; Peter Bader; A Böhme; H Martin; D Bunjes; WV Kern; Lothar Kanz; Hermann Einsele
Prospective screening by a panfungal polymerase chain reaction assay in patients at risk for fungal infections: implications for the management of febrile neutropenia.
British journal of haematology 2000;111(2):635-40.
2000: Peter Brossart; Stefan Wirths; Gernot Stuhler; Volker L Reichardt; Lothar Kanz; Wolfram Brugger
Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells.
Blood 2000;96(9):3102-8.
2000: Carsten Bokemeyer; Jörg Thomas Hartmann; Frank Mayer; I Böhlke; Lothar Kanz; Joachim von Pawel; Günter Derigs; M Schröder
UFT/leucovorin plus weekly paclitaxel in the treatment of solid tumors.
Oncology (Williston Park, N.Y.) 2000;14(10 Suppl 9):63-7.
2000: Jörg Thomas Hartmann; Lüder M Fels; A Franzke; Stefan Knop; M Renn; B Maess; P Panagiotou; H Lampe; Lothar Kanz; Hilmar Stolte; Carsten Bokemeyer
Comparative study of the acute nephrotoxicity from standard dose cisplatin +/- ifosfamide and high-dose chemotherapy with carboplatin and ifosfamide.
Anticancer research 2000;20(5C):3767-73.
2000: Christian Kollmannsberger; Craig Nichols; Christoph Meisner; Frank Mayer; Lothar Kanz; Carsten Bokemeyer
Identification of prognostic subgroups among patients with metastatic 'IGCCCG poor-prognosis' germ-cell cancer: an explorative analysis using cart modeling.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(9):1115-20.
2000: Robert Möhle; Marcus Schittenhelm; C Failenschmid; F Bautz; K Kratz-Albers; Hubert Serve; Wolfram Brugger; Lothar Kanz
Functional response of leukaemic blasts to stromal cell-derived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonocytic and lymphoblastic leukaemia.
British journal of haematology 2000;110(3):563-72.
2000: Peter Brossart; Anke Zobywalski; Frank Grünebach; L Behnke; Gernot Stuhler; Volker L Reichardt; Lothar Kanz; Wolfram Brugger
Tumor necrosis factor alpha and CD40 ligand antagonize the inhibitory effects of interleukin 10 on T-cell stimulatory capacity of dendritic cells.
Cancer research 2000;60(16):4485-92.
2000: Christian Kollmannsberger; Arthur Gerl; Norbert Schleucher; Jörg Beyer; Markus Kuczyk; Oliver Rick; Jochen Casper; M Sosada; C Rie; Lothar Kanz; Carsten Bokemeyer
Phase II study of bendamustine in patients with relapsed or cisplatin-refractory germ cell cancer.
Anti-cancer drugs 2000;11(7):535-9.
2000: Jörg Thomas Hartmann; Lüder M Fels; Stefan Knop; H Stolt; Lothar Kanz; Carsten Bokemeyer
A randomized trial comparing the nephrotoxicity of cisplatin/ifosfamide-based combination chemotherapy with or without amifostine in patients with solid tumors.
Investigational new drugs 2000;18(3):281-9.
2000: Christian Kollmannsberger; Detlef Quietzsch; Caroline Haag; T Lingenfelser; M Schroeder; Jörg Thomas Hartmann; W Baronius; V Hempel; Michael Clemens; Lothar Kanz; Carsten Bokemeyer
A phase II study of paclitaxel, weekly, 24-hour continous infusion 5-fluorouracil, folinic acid and cisplatin in patients with advanced gastric cancer.
British journal of cancer 2000;83(4):458-62.
2000: F Bautz; Shahin Rafii; Lothar Kanz; Robert Möhle
Expression and secretion of vascular endothelial growth factor-A by cytokine-stimulated hematopoietic progenitor cells. Possible role in the hematopoietic microenvironment.
Experimental hematology 2000;28(6):700-6.
2000: Jörg Thomas Hartmann; Craig Nichols; Jean Pierre Droz; Alan Horwich; Arthur Gerl; Sophie D Fossa; Jörg Beyer; Jörg Pont; Lawrence Einhorn; Lothar Kanz; Carsten Bokemeyer
The relative risk of second nongerminal malignancies in patients with extragonadal germ cell tumors.
Cancer 2000;88(11):2629-35.
2000: Christian Kollmannsberger; Craig Nichols; D D; Jörg Thomas Hartmann; Norbert Schleucher; Jörg Beyer; P Schöfski; Günter Derigs; U Rüther; I Böhlke; Hans-J Schmoll; Lothar Kanz; Carsten Bokemeyer
First-line high-dose chemotherapy +/- radiation therapy in patients with metastatic germ-cell cancer and brain metastases.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(5):553-9.
2000: Holger Hebart; Jürgen Löffler; C Meisner; F Serey; D Schmidt; A Böhme; H Martin; A Engel; D Bunje; WV Kern; Ulrike Schumacher; Lothar Kanz; Hermann Einsele
Early detection of aspergillus infection after allogeneic stem cell transplantation by polymerase chain reaction screening.
The Journal of infectious diseases 2000;181(5):1713-9.
2000: Norbert Braun; Christoph Faul; Dorothee Wernet; M Schnaidt; Gernot Stuhler; Lothar Kanz; Teut Risler; Hermann Einsele
Successful transplantation of highly selected CD34+ peripheral blood stem cells in a HLA-sensitized patient treated with immunoadsorption onto protein A.
Transplantation 2000;69(8):1742-4.
2000: Stefan Scheding; Bernhard Meister; Hans-Jörg Bühring; C M Baum; J P Mc Kearn; TA Bock; Lothar Kanz; Wolfram Brugger
Effective ex vivo generation of granulopoietic postprogenitor cells from mobilized peripheral blood CD34(+) cells.
Experimental hematology 2000;28(4):460-70.
2000: Hermann Einsele; Holger Hebart; C Kauffmann-Schneider; Christian Sinzger; Gerhard Jahn; Peter Bader; Thomas Klingebiel; K Dietz; Jürgen Löffler; C Bokemeyer; CA Müller; Lothar Kanz
Risk factors for treatment failures in patients receiving PCR-based preemptive therapy for CMV infection.
Bone marrow transplantation 2000;25(7):757-63.
2000: Jörg Thomas Hartmann; Lothar Kanz; Carsten Bokemeyer
Phase II study of continuous 120-hour-infusion of mitomycin C as salvage chemotherapy in patients with progressive or rapidly recurrent gastrointestinal adenocarcinoma.
Anticancer research 2000;20(2B):1177-82.
2000: Wolfgang A Bethge; D Guggenberger; D D; Lothar Kanz; C Bokemeyer
Thyroid toxicity of treatment for Hodgkin's disease.
Annals of hematology 2000;79(3):114-8.
2000: K Kratz-Albers; Stefan Scheding; Robert Möhle; Hans-Jörg Bühring; C M Baum; J P Mc Kearn; T Büchner; Lothar Kanz; Wolfram Brugger
Effective ex vivo generation of megakaryocytic cells from mobilized peripheral blood CD34(+) cells with stem cell factor and promegapoietin.
Experimental hematology 2000;28(3):335-46.
2000: Alexander Kugler; Gernot Stuhler; Peter Walden; Gerhard Zöller; Anke Zobywalski; Peter Brossart; Uwe Trefzer; S Ullrich; Claudia A Müller; Volker Becker; Andreas Gross; Bernhard Hemmerlein; Lothar Kanz; Gerhard A Müller; Rolf-Hermann Ringert
Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids.
Nature medicine 2000;6(3):332-6.
2000: Ilhan Günaydin; Philippe Pereira; Thomas Daikeler; Martin Mohren; Jochen Trübenbach; Fritz Schick; Lothar Kanz; Ina Kötter
Magnetic resonance imaging guided corticosteroid injection of the sacroiliac joints in patients with therapy resistant spondyloarthropathy: a pilot study.
The Journal of rheumatology 2000;27(2):424-8.
2000: Jörg Thomas Hartmann; Craig Nichols; Jean Pierre Droz; Alan Horwich; Arthur Gerl; Sophie D Fossa; Jörg Beyer; Jörg Pont; Karim Fizazi; Lawrence Einhorn; Lothar Kanz; Carsten Bokemeyer
Hematologic disorders associated with primary mediastinal nonseminomatous germ cell tumors.
Journal of the National Cancer Institute 2000;92(1):54-61.
2000: Carsten Bokemeyer; Christian Kollmannsberger; Jörg Thomas Hartmann; Lothar Kanz
Follow up after primary treatment: curable diseases treated non-surgically.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11 Suppl 3():73-8.
2000: Jörg Thomas Hartmann; Stefan Knop; Lüder M Fels; A van Vangerow; Hilmar Stolte; Lothar Kanz; Carsten Bokemeyer
The use of reduced doses of amifostine to ameliorate nephrotoxicity of cisplatin/ifosfamide-based chemotherapy in patients with solid tumors.
Anti-cancer drugs 2000;11(1):1-6.
2000: W Vogel; Stefan Scheding; Lothar Kanz; Wolfram Brugger
Clinical applications of CD34(+) peripheral blood progenitor cells (PBPC).
Stem cells (Dayton, Ohio) 2000;18(2):87-92.
2000: Wolfram Brugger; Stefan Scheding; BL Ziegler; Hans-Jörg Bühring; Lothar Kanz
Ex vivo manipulation of hematopoietic stem and progenitor cells.
Seminars in hematology 2000;37(1 Suppl 2):42-9.
2000: Claudio Denzlinger; D Bowen; Dietmar Benz; KJ Gelly; Wolfram Brugger; Lothar Kanz
Low-dose melphalan induces favourable responses in elderly patients with high-risk myelodysplastic syndromes or secondary acute myeloid leukaemia.
British journal of haematology 2000;108(1):93-5.
1999: Peter Brossart; B Spahlinger; Frank Grünebach; Gernot Stuhler; Volker L Reichardt; Lothar Kanz
Induction of minor histocompatiblity antigen HA-1-specific cytotoxic T cells for the treatment of leukemia after allogeneic stem cell transplantation.
Blood 1999;94(12):4374-6.
1999: Jörg Thomas Hartmann; Christian Kollmannsberger; Lothar Kanz; Carsten Bokemeyer
Platinum organ toxicity and possible prevention in patients with testicular cancer.
International journal of cancer. Journal international du cancer 1999;83(6):866-9.
1999: Christian Kollmannsberger; Jörg Thomas Hartmann; Lothar Kanz; Carsten Bokemeyer
Therapy-related malignancies following treatment of germ cell cancer.
International journal of cancer. Journal international du cancer 1999;83(6):860-3.
1999: Carsten Bokemeyer; Christian Kollmannsberger; Andreas Harstrick; Jörg Beyer; Arthur Gerl; Jochen Casper; Bernd Metzner; Jörg Thomas Hartmann; Hans-J Schmoll; Lothar Kanz
Treatment of patients with cisplatin-refractory testicular germ-cell cancer. German Testicular Cancer Study Group (GTCSG).
International journal of cancer. Journal international du cancer 1999;83(6):848-51.
1999: Hermann Einsele; Lothar Kanz
[Allogeneic transplantation of stem cells].
Der Internist 1999;40(12):1249-56.
1999: Wolfgang A Bethge; R Beck; Gerhard Jahn; PM Mundinger; Lothar Kanz; Hermann Einsele
Successful treatment of human herpesvirus-6 encephalitis after bone marrow transplantation.
Bone marrow transplantation 1999;24(11):1245-8.
1999: Robert Möhle; C Failenschmid; F Bautz; Lothar Kanz
Overexpression of the chemokine receptor CXCR4 in B cell chronic lymphocytic leukemia is associated with increased functional response to stromal cell-derived factor-1 (SDF-1).
Leukemia 1999;13(12):1954-9.
1999: Christian Kollmannsberger; M Kuzcyk; Frank Mayer; Jörg Thomas Hartmann; Lothar Kanz; Carsten Bokemeyer
Late toxicity following curative treatment of testicular cancer.
Seminars in surgical oncology 1999;17(4):275-81.
1999: M Seiffert; C Cant; Z Chen; I Rappold; Wolfram Brugger; Lothar Kanz; E J Brown; A Ullrich; Hans-Jörg Bühring
Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47.
Blood 1999;94(11):3633-43.
1999: Christian Kollmannsberger; Harald Pressler; Frank Mayer; Lothar Kanz; Carsten Bokemeyer
Cisplatin-refractory, HER2/neu-expressing germ-cell cancer: induction of remission by the monoclonal antibody Trastuzumab.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(11):1393-4.
1999: Carsten Bokemeyer; Christian Kollmannsberger; Christoph Meisner; Andreas Harstrick; Jörg Beyer; Bernd Metzner; Jörg Thomas Hartmann; Hans-J Schmoll; Lawrence Einhorn; Lothar Kanz; Craig Nichols
First-line high-dose chemotherapy compared with standard-dose PEB/VIP chemotherapy in patients with advanced germ cell tumors: A multivariate and matched-pair analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(11):3450-6.
1999: Jörg Thomas Hartmann; Markus A Kuczyk; Christian Kollmannsberger; Lothar Kanz; Carsten Bokemeyer
Future prospects in the chemotherapy of metastatic nonseminomatous testicular germ-cell cancer.
World journal of urology 1999;17(5):324-33.
1999: Hans-Jörg Bühring; Paul J Simmons; M Pudney; Robert Müller; D Jarrossay; A van Agthoven; M Willheim; Wolfram Brugger; Peter Valent; Lothar Kanz
The monoclonal antibody 97A6 defines a novel surface antigen expressed on human basophils and their multipotent and unipotent progenitors.
Blood 1999;94(7):2343-56.
1999: Jörg Thomas Hartmann; Detlef Quietzsch; Thomas Daikeler; Christian Kollmannsberger; Frank Mayer; Lothar Kanz; Carsten Bokemeyer
Mitomycin C continuous infusion as salvage chemotherapy in pretreated patients with advanced gastric cancer.
Anti-cancer drugs 1999;10(8):729-33.
1999: Jörg Thomas Hartmann; Lothar Kanz; Carsten Bokemeyer
Diagnosis and treatment of patients with testicular germ cell cancer.
Drugs 1999;58(2):257-81.
1999: Hans-Jörg Bühring; M Seiffert; Anke Marxer; B Weiss; C Faul; Lothar Kanz; Wolfram Brugger
AC133 antigen expression is not restricted to acute myeloid leukemia blasts but is also found on acute lymphoid leukemia blasts and on a subset of CD34+ B-cell precursors.
Blood 1999;94(2):832-3.
1999: Carsten Bokemeyer; Jörg Thomas Hartmann; Christian Kollmannsberger; Frank Mayer; Lothar Kanz
UFT/calcium folinate plus weekly paclitaxel for solid tumors.
Oncology (Williston Park, N.Y.) 1999;13(7 Suppl 3):106-11.
1999: Peter Brossart; K S Heinrich; Gernot Stuhler; L Behnke; Volker L Reichardt; Stefan Stevanovic; A Muhm; Hans-Georg Rammensee; Lothar Kanz; Wolfram Brugger
Identification of HLA-A2-restricted T-cell epitopes derived from the MUC1 tumor antigen for broadly applicable vaccine therapies.
Blood 1999;93(12):4309-17.
1999: Christian Kollmannsberger; W Brugger; Jörg Thomas Hartmann; Franz Maurer; P Böhm; Lothar Kanz; Carsten Bokemeyer
Phase II study of oral trofosfamide as palliative therapy in pretreated patients with metastatic soft-tissue sarcoma.
Anti-cancer drugs 1999;10(5):453-6.
1999: BL Ziegler; Robert Müller; Mauro Valtieri; C P Lamping; CA Thomas; Marco Gabbianelli; Christina Giesert; Hans-Jörg Bühring; Lothar Kanz; Cesare Peschle
Unicellular-unilineage erythropoietic cultures: molecular analysis of regulatory gene expression at sibling cell level.
Blood 1999;93(10):3355-68.
1999: Sebastian Fetscher; Wolfram Brugger; R Engelhardt; Lothar Kanz; J Hasse; Hermann Frommhold; Winand Lange; Roland Mertelsmann
Standard- and high-dose etoposide, ifosfamide, carboplatin, and epirubicin in 107 patients with non-small-cell lung cancer: a mature follow-up report.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(5):605-7.
1999: Sebastian Fetscher; Wolfram Brugger; R Engelhardt; Lothar Kanz; J Hasse; Hermann Frommhold; Winand Lange; Roland Mertelsmann
Standard- and high-dose etoposide, ifosfamide, carboplatin, and epirubicin in 100 patients with small-cell lung cancer: a mature follow-up report.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(5):561-7.
1999: Stefan Scheding; H Franke; V Diehl; H E Wichmann; Wolfram Brugger; Lothar Kanz; S Schmitz
How many myeloid post-progenitor cells have to be transplanted to completely abrogate neutropenia after peripheral blood progenitor cell transplantation? Results of a computer simulation.
Experimental hematology 1999;27(5):956-65.
1999: Wolfram Brugger; Hans-Jörg Bühring; Frank Grünebach; Wichard Vogel; S Kaul; R Müller; Tim H Brümmendorf; BL Ziegler; I Rappold; Peter Brossart; Stefan Scheding; Lothar Kanz
Expression of MUC-1 epitopes on normal bone marrow: implications for the detection of micrometastatic tumor cells.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(5):1535-44.
1999: Wolfram Brugger; Peter Brossart; Stefan Scheding; Gernot Stuhler; K Heinrich; Volker L Reichardt; Frank Grünebach; Hans-Jörg Bühring; Lothar Kanz
Approaches to dendritic cell-based immunotherapy after peripheral blood stem cell transplantation.
Annals of the New York Academy of Sciences 1999;872():363-71.
1999: TA Bock; BL Ziegler; Hans-Jörg Bühring; Stefan Scheding; Wolfram Brugger; Lothar Kanz
Characterization of purified and ex vivo manipulated human hematopoietic progenitor and stem cells in xenograft recipients.
Annals of the New York Academy of Sciences 1999;872():200-7; discussion 207-10.
1999: Robert Möhle; F Bautz; Shahin Rafii; Malcolm A S Moore; Wolfram Brugger; Lothar Kanz
Regulation of transendothelial migration of hematopoietic progenitor cells.
Annals of the New York Academy of Sciences 1999;872():176-85; discussion 185-6.
1999: Hans-Jörg Bühring; M Seiffert; TA Bock; Stefan Scheding; A Thiel; A Scheffold; Lothar Kanz; Wolfram Brugger
Expression of novel surface antigens on early hematopoietic cells.
Annals of the New York Academy of Sciences 1999;872():25-38; discussion 38-9.
1999: TA Bock; Stefan Scheding; Wolfram Brugger; Lothar Kanz
Clinical use for expanded peripheral blood stem cells.
Baillière's best practice & research. Clinical haematology 1999;12(1-2):117-28.
1999: Bernhard Meister; Frank Grünebach; F Bautz; Wolfram Brugger; Franz-Martin Fink; Lothar Kanz; Robert Möhle
Expression of vascular endothelial growth factor (VEGF) and its receptors in human neuroblastoma.
European journal of cancer (Oxford, England : 1990) 1999;35(3):445-9.
1999: Gernot Stuhler; Anke Zobywalski; Frank Grünebach; Peter Brossart; Volker L Reichardt; H Barth; Stefan Stevanovic; Wolfram Brugger; Lothar Kanz; Stuart F Schlossman
Immune regulatory loops determine productive interactions within human T lymphocyte-dendritic cell clusters.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1532-5.
1999: Carsten Bokemeyer; Arthur Gerl; Patrick Schöffski; Andreas Harstrick; N Niederle; Jörg Beyer; Jochen Casper; Hans-J Schmoll; Lothar Kanz
Gemcitabine in patients with relapsed or cisplatin-refractory testicular cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(2):512-6.
1999: Rupert Handgretinger; A Geiselhart; Arnaud Moris; R Grau; O Teuffel; Wolfgang A Bethge; Lothar Kanz; Paul Fisch
Pure red-cell aplasia associated with clonal expansion of granular lymphocytes expressing killer-cell inhibitory receptors.
The New England journal of medicine 1999;340(4):278-84.
1999: Ilhan Günaydin; T Terhorst; Anja Katrin Eckstein; Thomas Daikeler; Lothar Kanz; Ina Kötter
Assessment of keratoconjunctivitis sicca in patients with fibromyalgia: results of a prospective study.
Rheumatology international 1999;19(1-2):7-9.
1999: Thomas Daikeler; Ilhan Günaydin; H Einsele; Lothar Kanz; Ina Kötter
Transmission of psoriatic arthritis by allogeneic bone marrow transplantation for chronic myelogenous leukaemia from an HLA-identical donor.
Rheumatology (Oxford, England) 1999;38(1):89-90.
1999: Ilhan Günaydin; Thomas Daikeler; Martin Mohren; Lothar Kanz; Ina Kötter
Lower limb pitting edema in systemic lupus erythematosus.
Rheumatology international 1999;18(4):159-60.
1999: A Wiesmann; A Weller; G Lischka; Thomas Klingebiel; Lothar Kanz; Hermann Einsele
Treatment of acute graft-versus-host disease with PUVA (psoralen and ultraviolet irradiation): results of a pilot study.
Bone marrow transplantation 1999;23(2):151-5.
1999: Christian Kollmannsberger; K Mross; Andreas Jakob; Lothar Kanz; Carsten Bokemeyer
Topotecan - A novel topoisomerase I inhibitor: pharmacology and clinical experience.
Oncology 1999;56(1):1-12.
1998: D T Bowen; Claudio Denzlinger; Wolfram Brugger; D Culligan; KJ Gelly; S Adlakha; M Groves; MD Hepburn; Lothar Kanz
Poor response rate to a continuous schedule of Amifostine therapy for 'low/intermediate risk' myelodysplastic patients.
British journal of haematology 1998;103(3):785-7.
1998: Peter Brossart; Frank Grünebach; Gernot Stuhler; Volker L Reichardt; Robert Möhle; Lothar Kanz; Wolfram Brugger
Generation of functional human dendritic cells from adherent peripheral blood monocytes by CD40 ligation in the absence of granulocyte-macrophage colony-stimulating factor.
Blood 1998;92(11):4238-47.
1998: Andreas Jakob; Christian Kollmannsberger; Lothar Kanz; Carsten Bokemeyer
[Late toxicity after chemotherapy of malignant testicular tumors].
Der Urologe. Ausg. A 1998;37(6):635-47.
1998: BL Ziegler; Lothar Kanz
Expansion of stem and progenitor cells.
Current opinion in hematology 1998;5(6):434-40.
1998: Christian Kollmannsberger; Jörg Beyer; Jean Pierre Droz; Andreas Harstrick; Jörg Thomas Hartmann; Pierre Biron; Aude Fléchon; Patrick Schöffski; Markus Kuczyk; Hans-J Schmoll; Lothar Kanz; Carsten Bokemeyer
Secondary leukemia following high cumulative doses of etoposide in patients treated for advanced germ cell tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(10):3386-91.
1998: A Wiesmann; P Pereira; P Böhm; Christoph Faul; Lothar Kanz; Hermann Einsele
Avascular necrosis of bone following allogeneic stem cell transplantation: MR screening and therapeutic options.
Bone marrow transplantation 1998;22(6):565-9.
1998: Stefan Scheding; K Kratz-Albers; Bernhard Meister; Wolfram Brugger; Lothar Kanz
Ex vivo expansion of hematopoietic progenitor cells for clinical use.
Seminars in hematology 1998;35(3):232-40.
1998: Jörg Thomas Hartmann; Claus-Henning Köhne; H J Schmoll; Thomas Daikeler; Lothar Kanz; Carsten Bokemeyer
Is continuous 24-hour infusion of 5-fluorouracil plus high-dose folinic acid effective in patients with progressive or recurrent colorectal cancer? A phase II study.
Oncology 1998;55(4):320-5.
1998: Robert Möhle; F Bautz; Shahin Rafii; Malcolm A S Moore; Wolfram Brugger; Lothar Kanz
The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1.
Blood 1998;91(12):4523-30.
1998: Jörg Thomas Hartmann; Andreas Harstrick; Thomas Daikeler; Christian Kollmannsberger; C Müller; S Seeber; Lothar Kanz; Carsten Bokemeyer
Phase II study of continuous 120 h infusion of mitomycin C as salvage chemotherapy in patients with progressive or rapidly recurrent colorectal cancer.
Anti-cancer drugs 1998;9(5):427-31.
1998: Holger Hebart; D Gamer; Juergen Loeffler; C Mueller; Christian Sinzger; Gerhard Jahn; Peter Bader; T Klingebiel; Lothar Kanz; Hermann Einsele
Evaluation of Murex CMV DNA hybrid capture assay for detection and quantitation of cytomegalovirus infection in patients following allogeneic stem cell transplantation.
Journal of clinical microbiology 1998;36(5):1333-7.
1998: Carsten Bokemeyer; C C Berger; Jörg Thomas Hartmann; Christian Kollmannsberger; Hans-J Schmoll; Markus A Kuczyk; Lothar Kanz
Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer.
British journal of cancer 1998;77(8):1355-62.
1998: Carsten Bokemeyer; Andreas Harstrick; Jörg Beyer; Bernd Metzner; U Rüther; J T Hartmann; K Holstein; Hans Günter Derigs; R de Wit; J Casper; Patrick Schöffski; I Kührer; Hans-Jochen Illiger; B Kempf; A Reichle; A Föller; Dieter K Hossfeld; J T Fischer; W E Berdel; H H Gerhartz; H Kirchner; K H Pflüger; Helmut Ostermann; Lothar Kanz; H J Schmoll
The use of dose-intensified chemotherapy in the treatment of metastatic nonseminomatous testicular germ cell tumors. German Testicular Cancer Study Group.
Seminars in oncology 1998;25(2 Suppl 4):24-32; discussion 45-8.
1998: Peter Brossart; Gernot Stuhler; Thomas Flad; Stefan Stevanovic; Hans-Georg Rammensee; Lothar Kanz; Wolfram Brugger
Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes.
Cancer research 1998;58(4):732-6.
1998: Wolfram Brugger; Sebastian Fetscher; J Hasse; Hermann Frommhold; K Pressler; Roland Mertelsmann; R Engelhardt; Lothar Kanz
Multimodality treatment including early high-dose chemotherapy with peripheral blood stem cell transplantation in limited-disease small cell lung cancer.
Seminars in oncology 1998;25(1 Suppl 2):42-8.
1998: Andreas Jakob; Lothar Kanz
[Diagnostic criteria in polycythemia vera].
Deutsche medizinische Wochenschrift (1946) 1998;123(1-2):30-1.
1998: Carsten Bokemeyer; Jörg Thomas Hartmann; Markus A Kuczyk; M C Truss; Christian Kollmannsberger; Jörg Beyer; Udo Jonas; Lothar Kanz
Recent strategies for the use of paclitaxel in the treatment of urological malignancies.
World journal of urology 1998;16(2):155-62.
1998: Lothar Kanz; Wolfram Brugger; Stefan Scheding
Ex vivo manipulation of hematopoietic stem and progenitor cells.
Stem cells (Dayton, Ohio) 1998;16 Suppl 1():199-204.
1998: Ilhan Günaydin; Thomas Daikeler; S Jacki; Martin Mohren; Lothar Kanz; Ina Kötter
Articular involvement in patients with relapsing polychondritis.
Rheumatology international 1998;18(3):93-6.
1998: Christian Kollmannsberger; Jörg Thomas Hartmann; Lothar Kanz; Carsten Bokemeyer
Risk of secondary myeloid leukemia and myelodysplastic syndrome following standard-dose chemotherapy or high-dose chemotherapy with stem cell support in patients with potentially curable malignancies.
Journal of cancer research and clinical oncology 1998;124(3-4):207-14.
1998: Ilhan Günaydin; Ina Kötter; S Jacki; Thomas Daikeler; Lothar Kanz
Collagenous colitis associated with rheumatoid arthritis and anticardiolipin antibodies.
Clinical rheumatology 1998;17(1):79-80.
1998: Holger Hebart; Lothar Kanz; Gerhard Jahn; Hermann Einsele
Management of cytomegalovirus infection after solid-organ or stem-cell transplantation. Current guidelines and future prospects.
Drugs 1998;55(1):59-72.
1997: Carsten Bokemeyer; Jörg Thomas Hartmann; C S Lampe; M R Clemens; Detlef Quietzsch; L Forkmann; Lothar Kanz
Paclitaxel and weekly 24-hour infusion of 5-fluorouracil/folinic acid in advanced gastric cancer.
Seminars in oncology 1997;24(6 Suppl 19):S19-96-S19-100.
1997: Lothar Kanz
[High dose therapy and stem cell transplantation. A new path in tumor therapy].
Der Internist 1997;38(11):1045-9.
1997: Sebastian Fetscher; Wolfram Brugger; Hartmut Bertz; G Krieger; Lothar Kanz; Roland Mertelsmann; Winand Lange
High-dose chemotherapy with autologous peripheral blood stem cell transplantation for metastatic gastric leiomyosarcoma.
Bone marrow transplantation 1997;20(9):787-8.
1997: Carsten Bokemeyer; A Franzke; Jörg Thomas Hartmann; C Schöber; L Arseniev; Bernd Metzner; H Link; Lothar Kanz; Hans-J Schmoll
A phase I/II study of sequential, dose-escalated, high dose ifosfamide plus doxorubicin with peripheral blood stem cell support for the treatment of patients with advanced soft tissue sarcomas.
Cancer 1997;80(7):1221-7.
1997: Thomas Daikeler; K Maas; Jörg Thomas Hartmann; Lothar Kanz; Carsten Bokemeyer
Weekly short infusions of gemcitabine are not associated with suppression of lymphatic activity in patients with solid tumors.
Anti-cancer drugs 1997;8(6):643-4.
1997: I Rappold; BL Ziegler; I Köhler; Sylvie Marchetto; O Rosnet; Daniel Birnbaum; Paul J Simmons; Andrew C W Zannettino; B Hill; S Neu; W Knapp; Riitta Alitalo; Kari Alitalo; A Ullrich; Lothar Kanz; Hans-Jörg Bühring
Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase.
Blood 1997;90(1):111-25.
1997: Holger Hebart; A Schröder; Jürgen Löffler; Thomas Klingebiel; H Martin; B Wassmann; F Gerneth; H Rabenau; Gerhard Jahn; Lothar Kanz; CA Müller; Hermann Einsele
Cytomegalovirus monitoring by polymerase chain reaction of whole blood samples from patients undergoing autologous bone marrow or peripheral blood progenitor cell transplantation.
The Journal of infectious diseases 1997;175(6):1490-3.
1997: Hermann Einsele; Holger Hebart; G Roller; Jürgen Löffler; I Rothenhofer; CA Müller; R A Bowden; Jo-Anne H van Burik; D Engelhard; Lothar Kanz; Ulrike Schumacher
Detection and identification of fungal pathogens in blood by using molecular probes.
Journal of clinical microbiology 1997;35(6):1353-60.
1997: FC Dimeo; M H Tilmann; H Bertz; Lothar Kanz; Roland Mertelsmann; Joseph Keul
Aerobic exercise in the rehabilitation of cancer patients after high dose chemotherapy and autologous peripheral stem cell transplantation.
Cancer 1997;79(9):1717-22.
1997: Carsten Bokemeyer; C S Lampe; M R Clemens; Jörg Thomas Hartmann; Detlef Quietzsch; L Forkmann; Christian Kollmannsberger; Lothar Kanz
A phase II trial of paclitaxel and weekly 24 h infusion of 5-fluorouracil/folinic acid in patients with advanced gastric cancer.
Anti-cancer drugs 1997;8(4):396-9.
1997: Sebastian Fetscher; Michael Lübbert; Lothar Kanz; Dirk Behringer; Jürgen Finke; Roland Mertelsmann; Winand Lange
Treatment of relapsed non-Hodgkin's lymphoma after BEAM chemotherapy and autologous transplantation by BU/CY chemotherapy and salvage transplantation.
Bone marrow transplantation 1997;19(5):527-8.
1997: Wolfram Brugger; Stefan Scheding; TA Bock; BL Ziegler; Lothar Kanz
Purging of peripheral blood progenitor cell autografts and treatment of minimal residual disease.
Stem cells (Dayton, Ohio) 1997;15 Suppl 1():159-65.
1997: Sebastian Fetscher; Wolfram Brugger; R Engelhardt; Lothar Kanz; J Hasse; Hermann Frommhold; M Wenger; Winand Lange; Roland Mertelsmann
Dose-intense therapy with etoposide, ifosfamide, cisplatin, and epirubicin (VIP-E) in 107 consecutive patients with limited- and extensive-stage non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8(1):57-64.
1997: Sebastian Fetscher; Wolfram Brugger; R Engelhardt; Lothar Kanz; J Hasse; Hermann Frommhold; M Wenger; Winand Lange; Roland Mertelsmann
Dose-intense therapy with etoposide, ifosfamide, cisplatin, and epirubicin (VIP-E) in 100 consecutive patients with limited- and extensive-disease small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8(1):49-56.
1996: Jürgen Finke; Wolfram Brugger; Hartmut Bertz; Dirk Behringer; Regina Kunzmann; R M Weber-Nordt; Lothar Kanz; Roland Mertelsmann
Allogeneic transplantation of positively selected peripheral blood CD34+ progenitor cells from matched related donors.
Bone marrow transplantation 1996;18(6):1081-6.
1996: Holger Hebart; H Einsele; R Klein; I Fischer; S Bühler; K Dietz; Gerhard Jahn; P A Berg; Lothar Kanz; C A Müller
CMV infection after allogeneic bone marrow transplantation is associated with the occurrence of various autoantibodies and monoclonal gammopathies.
British journal of haematology 1996;95(1):138-44.
1996: W Vogel; Dirk Behringer; Stefan Scheding; Lothar Kanz; Wolfram Brugger
Ex vivo expansion of CD34+ peripheral blood progenitor cells: implications for the expansion of contaminating epithelial tumor cells.
Blood 1996;88(7):2707-13.
1996: Wolfram Brugger; Stefan Scheding; W Vogel; TA Bock; Hans-Jörg Bühring; BL Ziegler; Lothar Kanz
Ex vivo manipulations of CD34+ peripheral blood progenitor cells.
Bone marrow transplantation 1996;18 Suppl 1():S5-7.
1996: K Maas; Thomas Daikeler; Lothar Kanz; Carsten Bokemeyer
Activity of gemcitabine in platinum-resistant ovarian germ cell cancer.
European journal of cancer (Oxford, England : 1990) 1996;32A(8):1437-8.
1996: Wolfram Brugger; Lothar Kanz
Ex vivo expansion of hematopoietic precursor cells.
Current opinion in hematology 1996;3(3):235-40.
1996: Holger Hebart; C Erley; B Kaskas; R Mayer; M König; H Einsele; Carsten Bokemeyer; H G Meerpohl; U Feine; Lothar Kanz
Positron emission tomography helps to diagnose tumor emboli and residual disease in choriocarcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(4):416-8.
1996: Paul Fisch; G Köhler; A Garbe; B Herbst; D Wider; H Kohler; H E Schaefer; Roland Mertelsmann; W Brugger; Lothar Kanz
Generation of antigen-presenting cells for soluble protein antigens ex vivo from peripheral blood CD34+ hematopoietic progenitor cells in cancer patients.
European journal of immunology 1996;26(3):595-600.
1996: O Rosnet; Hans-Jörg Bühring; Sylvie Marchetto; I Rappold; C Lavagna; Danielle Sainty; Christine Arnoulet; Christian Chabannon; Lothar Kanz; C Hannum; Daniel Birnbaum
Human FLT3/FLK2 receptor tyrosine kinase is expressed at the surface of normal and malignant hematopoietic cells.
Leukemia 1996;10(2):238-48.
1996: Michael Lübbert; Wolfram Brugger; Roland Mertelsmann; Lothar Kanz
Developmental regulation of myeloid gene expression and demethylation during ex vivo culture of peripheral blood progenitor cells.
Blood 1996;87(2):447-55.
1996: Carsten Bokemeyer; Jörg Thomas Hartmann; M A Kuczyk; Michael C Truss; Jörg Beyer; Udo Jonas; Lothar Kanz
The role of paclitaxel in chemosensitive urological malignancies: current strategies in bladder cancer and testicular germ-cell tumors.
World journal of urology 1996;14(6):354-9.
1996: Carsten Bokemeyer; M A Kuczyk; Jürgen Serth; Jörg Thomas Hartmann; H J Schmoll; Udo Jonas; Lothar Kanz
Treatment of clinical stage I testicular cancer and a possible role for new biological prognostic parameters.
Journal of cancer research and clinical oncology 1996;122(10):575-84.
1996: Wolfram Brugger; Stefan Scheding; W Vogel; Lothar Kanz
Purging of peripheral blood progenitor cells.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7 Suppl 2():11-3.
1995: Dorothee von Laer; U Meyer-Koenig; A Serr; Jürgen Finke; Lothar Kanz; A A Fauser; Dieter Neumann-Haefelin; Wolfram Brugger; Frank T Hufert
Detection of cytomegalovirus DNA in CD34+ cells from blood and bone marrow.
Blood 1995;86(11):4086-90.
1995: Wolfram Brugger; S Heimfeld; R J Berenson; Roland Mertelsmann; Lothar Kanz
Reconstitution of hematopoiesis after high-dose chemotherapy by autologous progenitor cells generated ex vivo.
The New England journal of medicine 1995;333(5):283-7.
1995: Wolfram Brugger; Hermann Frommhold; K Pressler; Roland Mertelsmann; Lothar Kanz
Use of high-dose etoposide/ifosfamide/carboplatin/epirubicin and peripheral blood progenitor cell transplantation in limited-disease small cell lung cancer.
Seminars in oncology 1995;22(1 Suppl 2):3-8.
1994: Wolfram Brugger; R Engelhardt; Roland Mertelsmann; Lothar Kanz
The management of primary mediastinal B-cell lymphoma with sclerosis.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5(10):943-7.
1994: Lothar Kanz; Wolfram Brugger; Roland Mertelsmann
The use of hematopoietic growth factors for high-dose chemotherapy and peripheral blood progenitor cell transplantation.
Seminars in oncology 1994;21(6 Suppl 16):10-8.
1994: Reinhard Henschler; Wolfram Brugger; T Luft; T Frey; Roland Mertelsmann; Lothar Kanz
Maintenance of transplantation potential in ex vivo expanded CD34(+)-selected human peripheral blood progenitor cells.
Blood 1994;84(9):2898-903.
1994: Wolfram Brugger; Reinhard Henschler; S Heimfeld; R J Berenson; Roland Mertelsmann; Lothar Kanz
Positively selected autologous blood CD34+ cells and unseparated peripheral blood progenitor cells mediate identical hematopoietic engraftment after high-dose VP16, ifosfamide, carboplatin, and epirubicin.
Blood 1994;84(5):1421-6.
1994: Wolfram Brugger; K J Bross; M Glatt; F Weber; Roland Mertelsmann; Lothar Kanz
Mobilization of tumor cells and hematopoietic progenitor cells into peripheral blood of patients with solid tumors.
Blood 1994;83(3):636-40.
1994: Stefan Scheding; Wolfram Brugger; Roland Mertelsmann; Lothar Kanz
Peripheral blood stem cells: in vivo biology and therapeutic potential.
Stem cells (Dayton, Ohio) 1994;12 Suppl 1():203-10; discussion 211.
1994: Sebastian Fetscher; Wolfram Brugger; Roland Mertelsmann; Lothar Kanz
The clinical role of hematopoietic growth factors in peripheral blood progenitor cell transplantation.
Vox sanguinis 1994;67 Suppl 3():43-7.
1993: Wolfram Brugger; R Birken; Hartmut Bertz; T Hecht; K Pressler; J Frisch; G Schulz; Roland Mertelsmann; Lothar Kanz
Peripheral blood progenitor cells mobilized by chemotherapy plus granulocyte-colony stimulating factor accelerate both neutrophil and platelet recovery after high-dose VP16, ifosfamide and cisplatin.
British journal of haematology 1993;84(3):402-7.
1993: Wolfram Brugger; Roland Mertelsmann; Lothar Kanz
Mobilization, purification and ex vivo expansion of human peripheral blood progenitor cells.
Nouvelle revue française d'hématologie 1993;35(3):221-3.
1993: Wolfram Brugger; W Möcklin; S Heimfeld; R J Berenson; Roland Mertelsmann; Lothar Kanz
Ex vivo expansion of enriched peripheral blood CD34+ progenitor cells by stem cell factor, interleukin-1 beta (IL-1 beta), IL-6, IL-3, interferon-gamma, and erythropoietin.
Blood 1993;81(10):2579-84.
1993: Lothar Kanz; Wolfram Brugger; Roland Mertelsmann
Haematopoietic growth factors and peripheral blood stem cells as supportive agents in dose intensification.
European journal of cancer (Oxford, England : 1990) 1993;29A Suppl 5():S23-6.
1992: Wolfram Brugger; J Frisch; G Schulz; K Pressler; Roland Mertelsmann; Lothar Kanz
Sequential administration of interleukin-3 and granulocyte-macrophage colony-stimulating factor following standard-dose combination chemotherapy with etoposide, ifosfamide, and cisplatin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(9):1452-9.
1992: F Herrmann; Wolfram Brugger; Lothar Kanz; Roland Mertelsmann
In vivo biology and therapeutic potential of hematopoietic growth factors and circulating progenitor cells.
Seminars in oncology 1992;19(4):422-31.
1992: Arnold Ganser; A Lindemann; Oliver G Ottmann; Gernot Seipelt; U Hess; G Geissler; Lothar Kanz; J Frisch; G Schulz; F Herrmann
Sequential in vivo treatment with two recombinant human hematopoietic growth factors (interleukin-3 and granulocyte-macrophage colony-stimulating factor) as a new therapeutic modality to stimulate hematopoiesis: results of a phase I study.
Blood 1992;79(10):2583-91.
1992: Wolfram Brugger; K J Bross; A Lindemann; Lothar Kanz; Roland Mertelsmann
Role of hematopoietic growth factor combinations in experimental and clinical oncology.
Seminars in oncology 1992;19(2 Suppl 4):8-15.
1992: Wolfram Brugger; K Bross; J Frisch; P Dern; B Weber; Roland Mertelsmann; Lothar Kanz
Mobilization of peripheral blood progenitor cells by sequential administration of interleukin-3 and granulocyte-macrophage colony-stimulating factor following polychemotherapy with etoposide, ifosfamide, and cisplatin.
Blood 1992;79(5):1193-200.
1992: J Frisch; Arnold Ganser; Dieter Hoelzer; Wolfram Brugger; Lothar Kanz; Roland Mertelsmann; G Schulz
Interleukin-3 and granulocyte-macrophage colony-stimulating factor in combination: clinical implication.
Medical and pediatric oncology. Supplement 1992;2():34-7.
1991: Lothar Kanz; Wolfram Brugger; K Bross; Roland Mertelsmann
Combination of cytokines: current status and future prospects.
British journal of haematology 1991;79 Suppl 1():96-104.
1991: Winand Lange; A Luig; G Dölken; Roland Mertelsmann; Lothar Kanz
Fibrinogen gamma-chain mRNA is not detected in human megakaryocytes.
Blood 1991;78(1):20-5.
1991: W Lange; Wolfram Brugger; Felicia M Rosenthal; Lothar Kanz; A Lindemann
The role of cytokines in oncology.
International journal of cell cloning 1991;9(4):252-73.
1991: Lothar Kanz; A Lindemann; Wolfgang Oster; F Herrmann; Roland Mertelsmann
Hemopoietins in clinical oncology.
American journal of clinical oncology 1991;14 Suppl 1():S27-33.
1991: Wolfram Brugger; Felicia M Rosenthal; Lothar Kanz; Roland Mertelsmann
Clinical role of colony stimulating factors.
Acta haematologica 1991;86(3):138-47.
1990: Lothar Kanz; R Mertelsmann
[Proliferation and differentiation in megakaryopoiesis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():28-35.
1988: Lothar Kanz; R Mielke; A A Fauser
Analysis of human hemopoietic progenitor cells for the expression of glycoprotein IIIa.
Experimental hematology 1988;16(9):741-7.
1988: Lothar Kanz; R Mielke; A A Fauser; G W Löhr
Evaluation of c-sis mRNA expression by human megakaryocytic cells in normals and patients with myeloproliferative disorders.
Advances in experimental medicine and biology 1988;241():73-80.