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Feige Kaplan

Research Profile

Disorders

Tay-Sachs Disease

Chemicals & Drugs

Anatomy

Lung

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Physiology

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Quebec

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Publications

TOP 3
Neetu Manwani; Stéphane Gagnon; Martin Post; Stephen Joza; Louis Muglia; Salomon Cornejo; Feige Kaplan; Neil B Sweezey
Reduced viability of mice with lung epithelial-specific knockout of glucocorticoid receptor.
Jeremy R Grushka; Saleh Al-Abbad; Robert Baird; Pramod S Puligandla; Feige Kaplan; Jean-Martin Laberge
The effect of in vitro tracheal occlusion on branching morphogenesis in fetal lung explants from the rat nitrofen model of congenital diaphragmatic hernia.
Katia Nadeau; Laura Montermini; Isabel Mandeville; Mousheng Xu; Scott T Weiss; Neil B Sweezey; Feige Kaplan
Modulation of Lgl1 by steroid, retinoic acid, and vitamin D models complex transcriptional regulation during alveolarization.

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All Publications

2010: Neetu Manwani; Stéphane Gagnon; Martin Post; Stephen Joza; Louis Muglia; Salomon Cornejo; Feige Kaplan; Neil B Sweezey
Reduced viability of mice with lung epithelial-specific knockout of glucocorticoid receptor.
American journal of respiratory cell and molecular biology 2010;43(5):599-606.
2010: Jeremy R Grushka; Saleh Al-Abbad; Robert Baird; Pramod S Puligandla; Feige Kaplan; Jean-Martin Laberge
The effect of in vitro tracheal occlusion on branching morphogenesis in fetal lung explants from the rat nitrofen model of congenital diaphragmatic hernia.
Journal of pediatric surgery 2010;45(5):943-7.
2010: Katia Nadeau; Laura Montermini; Isabel Mandeville; Mousheng Xu; Scott T Weiss; Neil B Sweezey; Feige Kaplan
Modulation of Lgl1 by steroid, retinoic acid, and vitamin D models complex transcriptional regulation during alveolarization.
Pediatric research 2010;67(4):375-81.
2009: Jie Lan; Leslie Ribeiro; Isabel Mandeville; Katia Nadeau; Tim Bao; Salomon Cornejo; Neil B Sweezey; Feige Kaplan
Inflammatory cytokines, goblet cell hyperplasia and altered lung mechanics in Lgl1+/- mice.
Respiratory research 2009;10():83.
2009: Huayan Zhang; Samuel J Garber; Zheng Cui; Joseph P Foley; Gopi S Mohan; Minesh Jobanputra; Feige Kaplan; Neil B Sweezey; Linda W Gonzales; Rashmin C Savani
The angiogenic factor midkine is regulated by dexamethasone and retinoic acid during alveolarization and in alveolar epithelial cells.
Respiratory research 2009;10():77.
2008: Baharak Nemati; Wayhuni Atmodjo; Stéphane Gagnon; Daryl Humes; Colin McKerlie; Feige Kaplan; Neil B Sweezey
Glucocorticoid receptor disruption delays structural maturation in the lungs of newborn mice.
Pediatric pulmonology 2008;43(2):125-33.
2008: Jie Liang; Guifen Ke; Wenjun You; Zi Peng; Jie Lan; Markus Kalesse; Alan M Tartakoff; Feige Kaplan; Tao Tao
Interaction between importin 13 and myopodin suggests a nuclear import pathway for myopodin.
Molecular and cellular biochemistry 2008;307(1-2):93-100.
2007: Jacklyn Quinlan; Feige Kaplan; Neil B Sweezey; Paul Goodyer
LGL1, a novel branching morphogen in developing kidney, is induced by retinoic acid.
American journal of physiology. Renal physiology 2007;293(4):F987-93.
2006: Tao Tao; Jie Lan; Gergely L Lukacs; Robert J G Haché; Feige Kaplan
Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells.
American journal of respiratory cell and molecular biology 2006;35(6):668-80.
2006: Katia Nadeau; Robert P Jankov; A Keith Tanswell; Neil B Sweezey; Feige Kaplan
Lgl1 is suppressed in oxygen toxicity animal models of bronchopulmonary dysplasia and normalizes during recovery in air.
Pediatric research 2006;59(3):389-95.
2006: Stéphane Gagnon; Wayhuni Atmodjo; Daryl Humes; Colin McKerlie; Feige Kaplan; Neil B Sweezey
Transgenic glucocorticoid receptor expression driven by the SP-C promoter reduces neonatal lung cellularity and midkine expression in GRhypo mice.
Biology of the neonate 2006;90(1):46-57.
2004: Tao Tao; Jie Lan; John F Presley; Neil B Sweezey; Feige Kaplan
Nucleocytoplasmic shuttling of lgl2 is developmentally regulated in fetal lung.
American journal of respiratory cell and molecular biology 2004;30(3):350-9.
2003: Lami Oyewumi; Feige Kaplan; Neil B Sweezey
Lgl1, a mesenchymal modulator of early lung branching morphogenesis, is a secreted glycoprotein imported by late gestation lung epithelial cells.
The Biochemical journal 2003;376(Pt 1):61-9.
2003: Ewa Zietkiewicz; Vania Yotova; Dominik Gehl; Tina Wambach; Isabel Arrieta; Mark A Batzer; David E C Cole; Peter Hechtman; Feige Kaplan; David Modiano; Jean-Paul Moisan; Roman Michalski; Damian Labuda
Haplotypes in the dystrophin DNA segment point to a mosaic origin of modern human diversity.
American journal of human genetics 2003;73(5):994-1015.
2003: Lami Oyewumi; Feige Kaplan; Stéphane Gagnon; Neil B Sweezey
Antisense oligodeoxynucleotides decrease LGL1 mRNA and protein levels and inhibit branching morphogenesis in fetal rat lung.
American journal of respiratory cell and molecular biology 2003;28(2):232-40.
2003: Feige Kaplan; Julie Comber; Robert Sladek; Thomas J Hudson; Louis J Muglia; Tara Macrae; Stéphane Gagnon; Minoru Asada; Judson Brewer; Neil B Sweezey
The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development.
American journal of respiratory cell and molecular biology 2003;28(1):33-41.
2002: Feige Kaplan; Tara MacRae; Julie Comber; Stéphane Gagnon; Robert Sladek; Thomas J Hudson; Neil B Sweezey
Application of expression microarrays to the investigation of fetal lung development in a glucocorticoid receptor knockout mouse model.
Chest 2002;121(3 Suppl):90S.
2000: P Cordeiro; Peter Hechtman; Feige Kaplan
The GM2 gangliosidoses databases: allelic variation at the HEXA, HEXB, and GM2A gene loci.
Genetics in medicine : official journal of the American College of Medical Genetics 2000;2(6):319-27.
2000: Feige Kaplan
Molecular determinants of fetal lung organogenesis.
Molecular genetics and metabolism 2000;71(1-2):321-41.
2000: C Zhang; Neil B Sweezey; Stéphane Gagnon; B Muskat; David R Koehler; Martin Post; Feige Kaplan
A novel karyopherin-beta homolog is developmentally and hormonally regulated in fetal lung.
American journal of respiratory cell and molecular biology 2000;22(4):451-9.
1999: Feige Kaplan; P Ledoux; F Q Kassamali; Stéphane Gagnon; Martin Post; David R Koehler; J Deimling; Neil B Sweezey
A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
The American journal of physiology 1999;276(6 Pt 1):L1027-36.
1998: Feige Kaplan
Tay-Sachs disease carrier screening: a model for prevention of genetic disease.
Genetic testing 1998;2(4):271-92.
1997: F Yadao; Peter Hechtman; Feige Kaplan
Formation of a ternary complex between GM2 activator protein, GM2 ganglioside and hexosaminidase A.
Biochimica et biophysica acta 1997;1340(1):45-52.
1997: M J Fernandes; Peter Hechtman; B Boulay; Feige Kaplan
A chronic GM2 gangliosidosis variant with a HEXA splicing defect: quantitation of HEXA mRNAs in normal and mutant fibroblasts.
European journal of human genetics : EJHG 1997;5(3):129-36.
1997: M J Fernandes; S Yew; Daniel Leclerc; Bernard Henrissat; C E Vorgias; Roy A Gravel; Peter Hechtman; Feige Kaplan
Identification of candidate active site residues in lysosomal beta-hexosaminidase A.
The Journal of biological chemistry 1997;272(2):814-20.
1997: T Martino; Feige Kaplan; S Diamond; A Oppenheim; Charles R Scriver
Probable identity by descent and discovery of familial relationships by means of a rare beta-thalassemia haplotype.
Human mutation 1997;9(1):86-7.
1996: Y Hou; G Vavougios; Aleksander Hinek; K K Wu; Peter Hechtman; Feige Kaplan; Don J Mahuran
The Val192Leu mutation in the alpha-subunit of beta-hexosaminidase A is not associated with the B1-variant form of Tay-Sachs disease.
American journal of human genetics 1996;59(1):52-8.
1993: Peter Hechtman; Feige Kaplan
Tay-Sachs disease screening and diagnosis: evolving technologies.
DNA and cell biology 1993;12(8):651-65.
1993: J Mitchell; Charles R Scriver; C L Clow; Feige Kaplan
What young people think and do when the option for cystic fibrosis carrier testing is available.
Journal of medical genetics 1993;30(7):538-42.
1993: Feige Kaplan; S Kapoor; D Lee; M Fernandes; M Vienozinskis; A Mascisch; Charles R Scriver; J Lim-Steele; M Kaback; K Zeiger; A Zoossman-Diskin; B Bonne-Tamir; E Landels; M Bobrow; P Hechtman
A Pst+ polymorphism in the HEXA gene with an unusual geographic distribution.
European journal of human genetics : EJHG 1993;1(4):301-5.
1992: Peter Hechtman; B Boulay; Marc de Braekeleer; Eva Andermann; SB Melançon; J Larochelle; C Prevost; Feige Kaplan
The intron 7 donor splice site transition: a second Tay-Sachs disease mutation in French Canada.
Human genetics 1992;90(4):402-6.
1992: M Fernandes; Feige Kaplan; Marvin R Natowicz; E Prence; E Kolodny; M Kaback; Peter Hechtman
A new Tay-Sachs disease B1 allele in exon 7 in two compound heterozygotes each with a second novel mutation.
Human molecular genetics 1992;1(9):759-61.
1992: Marc de Braekeleer; Peter Hechtman; Eva Andermann; Feige Kaplan
The French Canadian Tay-Sachs disease deletion mutation: identification of probable founders.
Human genetics 1992;89(1):83-7.
1992: M J Fernandes; Feige Kaplan; C L Clow; Peter Hechtman; Charles R Scriver
Specificity and sensitivity of hexosaminidase assays and DNA analysis for the detection of Tay-Sachs disease gene carriers among Ashkenazic Jews.
Genetic epidemiology 1992;9(3):169-75.
1992: N Akalin; H P Shi; G Vavougios; Peter Hechtman; W Lo; Charles R Scriver; Don J Mahuran; Feige Kaplan
Novel Tay-Sachs disease mutations from China.
Human mutation 1992;1(1):40-6.
1992: I Trop; Feige Kaplan; C Brown; Don J Mahuran; Peter Hechtman
A glycine250--> aspartate substitution in the alpha-subunit of hexosaminidase A causes juvenile-onset Tay-Sachs disease in a Lebanese-Canadian family.
Human mutation 1992;1(1):35-9.
1991: Feige Kaplan; G Kokotsis; A Capua; Charles R Scriver
Quantitation of beta-thalassemia genes in Quebec immigrants of Mediterranean, southeast Asian, and Asian Indian origins.
Clinical and investigative medicine. Médecine clinique et experimentale 1991;14(4):325-30.
1991: Feige Kaplan; B Boulay; J Bayleran; Peter Hechtman
Allele-specific amplification of genomic DNA for detection of deletion mutations: identification of a French-Canadian Tay-Sachs mutation.
Journal of inherited metabolic disease 1991;14(5):707-14.
1990: Peter Hechtman; Feige Kaplan; J Bayleran; B Boulay; Eva Andermann; Marc de Braekeleer; SB Melançon; Marie Lambert; M Potier; R Gagné
More than one mutant allele causes infantile Tay-Sachs disease in French-Canadians.
American journal of human genetics 1990;47(5):815-22.
1990: Feige Kaplan; G Kokotsis; M DeBraekeleer; Kenneth Morgan; Charles R Scriver
Beta-thalassemia genes in French-Canadians: haplotype and mutation analysis of Portneuf chromosomes.
American journal of human genetics 1990;46(1):126-32.
1985: M Szyf; Feige Kaplan; V Mann; H Giloh; E Kedar; Aharon Razin
Cell cycle-dependent regulation of eukaryotic DNA methylase level.
The Journal of biological chemistry 1985;260(15):8653-6.
1984: M Szyf; K Avraham-Haetzni; A Reifman; J Shlomai; Feige Kaplan; A Oppenheim; Aharon Razin
DNA methylation pattern is determined by the intracellular level of the methylase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(11):3278-82.
1984: Feige Kaplan; Peter Hechtman
Rat liver Golgi galactosyltransferases. Distinct enzymes for glycolipid and glycoprotein acceptor substrates.
The Biochemical journal 1984;217(2):353-64.
1983: Feige Kaplan; Peter Hechtman
Purification and properties of two enzymes catalyzing galactose transfer to GM2 ganglioside from rat liver Golgi.
The Journal of biological chemistry 1983;258(2):770-6.