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Jerry Kaplan

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Rita Polati; Anna Maria Timperio; Lello Zolla; Jerry Kaplan; Oliviero Olivieri; Tiziana Alberio; Alessandra Maria Bossi; Ryan Brunch; Annalisa Castagna; Angelo D'Alessandro; Ivana De Domenico; Federica Gevi; Domenico Girelli
Murine macrophages response to iron.
Liangtao Li; Ren Miao; Diane M Ward; Sophie Bertram; Xuan Jia; Jerry Kaplan
A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeast.
Dustin C Bagley; Jerry Kaplan; Prasad N Paradkar; Diane M Ward
Mon1a protein acts in trafficking through the secretory apparatus.

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2012: Rita Polati; Anna Maria Timperio; Lello Zolla; Jerry Kaplan; Oliviero Olivieri; Tiziana Alberio; Alessandra Maria Bossi; Ryan Brunch; Annalisa Castagna; Angelo D'Alessandro; Ivana De Domenico; Federica Gevi; Domenico Girelli
Murine macrophages response to iron.
Journal of proteomics 2012;76 Spec No.():10-27.
2012: Liangtao Li; Ren Miao; Diane M Ward; Sophie Bertram; Xuan Jia; Jerry Kaplan
A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeast.
The Journal of biological chemistry 2012;287(42):35709-21.
2012: Dustin C Bagley; Jerry Kaplan; Prasad N Paradkar; Diane M Ward
Mon1a protein acts in trafficking through the secretory apparatus.
The Journal of biological chemistry 2012;287(30):25577-88.
2011: Liangtao Li; Diane M Ward; Xuan Jia; Jerry Kaplan
Yap5 protein-regulated transcription of the TYW1 gene protects yeast from high iron toxicity.
The Journal of biological chemistry 2011;286(44):38488-97.
2011: Ivana De Domenico; Iqbal Hamza; Tamara Korolnek; Eric Lo; Diane McVey Ward; Baoli Yang; Jerry Kaplan
The role of ubiquitination in hepcidin-independent and hepcidin-dependent degradation of ferroportin.
Cell metabolism 2011;14(5):635-46.
2011: Ivana De Domenico; Diane McVey Ward; Jerry Kaplan
Hepcidin and ferroportin: the new players in iron metabolism.
Seminars in liver disease 2011;31(3):272-9.
2011: Ivana De Domenico; Michael B Vaughn; Prasad N Paradkar; Eric Lo; Diane M Ward; Jerry Kaplan
Decoupling ferritin synthesis from free cytosolic iron results in ferritin secretion.
Cell metabolism 2011;13(1):57-67.
2011: Jerry Kaplan; Diane M Ward; Ivana De Domenico
The molecular basis of iron overload disorders and iron-linked anemias.
International journal of hematology 2011;93(1):14-20.
2010: Ivana De Domenico; Eric Lo; Diane M Ward; Jerry Kaplan
Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulation.
Blood 2010;115(14):2956-9.
2010: Liangtao Li; Grace Murdock; Dustin Bagley; Xuan Jia; Diane McVey Ward; Jerry Kaplan
Genetic dissection of a mitochondria-vacuole signaling pathway in yeast reveals a link between chronic oxidative stress and vacuolar iron transport.
The Journal of biological chemistry 2010;285(14):10232-42.
2010: Ivana De Domenico; Diane McVey Ward; Jerry Kaplan
Autophagy, ferritin and iron chelation.
Autophagy 2010;6(1):157.
2009: Ivana De Domenico; Jerry Kaplan
A new wrinkle in the fold: hepcidin links inflammation to the unfolded protein response.
Cell metabolism 2009;10(4):245-6.
2009: Craig D Kaplan; Jerry Kaplan
Iron acquisition and transcriptional regulation.
Chemical reviews 2009;109(10):4536-52.
2009: Wen Chen; Prasad N Paradkar; Liangtao Li; Eric L Pierce; Nathaniel B Langer; Naoko Takahashi-Makise; Brigham B Hyde; Orian S Shirihai; Diane M Ward; Jerry Kaplan; Barry H Paw
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16263-8.
2009: Huilan Lin; Damali Burton; Liangtao Li; David E Warner; John D Phillips; Diane McVey Ward; Jerry Kaplan
Gain-of-function mutations identify amino acids within transmembrane domains of the yeast vacuolar transporter Zrc1 that determine metal specificity.
The Biochemical journal 2009;422(2):273-83.
2009: Curry L Koening; Jennifer C Miller; Jenifer M Nelson; Diane McVey Ward; James P Kushner; Linda K Bockenstedt; Janis J Weis; Jerry Kaplan; Ivana De Domenico
Toll-like receptors mediate induction of hepcidin in mice infected with Borrelia burgdorferi.
Blood 2009;114(9):1913-8.
2009: Roland Nilsson; Iman J Schultz; Eric L Pierce; Kathleen A Soltis; Amornrat Naranuntarat; Diane M Ward; Joshua M Baughman; Prasad N Paradkar; Paul D Kingsley; Valeria Cizewski Culotta; Jerry Kaplan; James Palis; Barry H Paw; Vamsi K Mootha
Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.
Cell metabolism 2009;10(2):119-30.
2009: Augustine Fernandes; Gloria C Preza; Yen Phung; Ivana De Domenico; Jerry Kaplan; Tomas Ganz; Elizabeta Nemeth
The molecular basis of hepcidin-resistant hereditary hemochromatosis.
Blood 2009;114(2):437-43.
2009: Ivana De Domenico; Eric Lo; Diane McVey Ward; Jerry Kaplan
Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3800-5.
2009: Ivana De Domenico; Diane McVey Ward; Jerry Kaplan
Serum ferritin regulates blood vessel formation: a role beyond iron storage.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1683-4.
2009: Prasad N Paradkar; Kimberley B Zumbrennen; Barry H Paw; Diane M Ward; Jerry Kaplan
Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2.
Molecular and cellular biology 2009;29(4):1007-16.
2009: Curry L Koening; Hong Hua Mu; Adam Van Schelt; Eric Lo; Diane M Ward; Jerry Kaplan; Ivana De Domenico
Hepcidin is elevated in mice injected with Mycoplasma arthritidis.
Journal of inflammation (London, England) 2009;6():33.
2009: marie-berengere troadec; Diane M Ward; Jerry Kaplan
A Tf-independent iron transport system required for organogenesis.
Developmental cell 2009;16(1):3-4.
2008: Huilan Lin; Attila Kumánovics; Jenifer M Nelson; David E Warner; Diane McVey Ward; Jerry Kaplan
A single amino acid change in the yeast vacuolar metal transporters ZRC1 and COT1 alters their substrate specificity.
The Journal of biological chemistry 2008;283(49):33865-73.
2008: Domenico Girelli; Ivana De Domenico; Claudia Bozzini; Natascia Campostrini; Fabiana Busti; Annalisa Castagna; Nadia Soriani; Laura Cremonesi; Maurizio Ferrari; Romano Colombari; Diane McVey Ward; Jerry Kaplan; Roberto Corrocher
Clinical, pathological, and molecular correlates in ferroportin disease: a study of two novel mutations.
Journal of hepatology 2008;49(4):664-71.
2008: Ivana De Domenico; Elizabeta Nemeth; Jenifer M Nelson; John D Phillips; Richard S Ajioka; Michael S Kay; James P Kushner; Tomas Ganz; Diane M Ward; Jerry Kaplan
The hepcidin-binding site on ferroportin is evolutionarily conserved.
Cell metabolism 2008;8(2):146-56.
2008: Prasad N Paradkar; Ivana De Domenico; Nina Durchfort; Irene Zohn; Jerry Kaplan; Diane McVey Ward
Iron depletion limits intracellular bacterial growth in macrophages.
Blood 2008;112(3):866-74.
2008: Collin Kieffer; Jack J Skalicky; Eiji Morita; Ivana De Domenico; Diane M Ward; Jerry Kaplan; Wesley I Sundquist
Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding.
Developmental cell 2008;15(1):62-73.
2008: Attila Kumánovics; Opal S. Chen; Liangtao Li; Dustin Bagley; Erika Adkins Scholl; Huilan Lin; Nin N Dingra; Caryn Outten; Greg Keller; Dennis R Winge; Diane McVey Ward; Jerry Kaplan
Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis.
The Journal of biological chemistry 2008;283(16):10276-86.
2008: marie-berengere troadec; Jerry Kaplan
Some vertebrates go with the GLO.
Cell 2008;132(6):921-2.
2008: Siobán B Keel; Raymond T Doty; Zhantao Yang; John Quigley; Jing Chen; Sue Knoblaugh; Paul D Kingsley; Ivana De Domenico; Michael B Vaughn; Jerry Kaplan; James Palis; Janis L Abkowitz
A heme export protein is required for red blood cell differentiation and iron homeostasis.
Science (New York, N.Y.) 2008;319(5864):825-8.
2008: Liangtao Li; Dustin Bagley; Diane M Ward; Jerry Kaplan
Yap5 is an iron-responsive transcriptional activator that regulates vacuolar iron storage in yeast.
Molecular and cellular biology 2008;28(4):1326-37.
2008: Jerry Kaplan; Ivana De Domenico; Diane McVey Ward
Chediak-Higashi syndrome.
Current opinion in hematology 2008;15(1):22-9.
2008: Ivana De Domenico; Diane McVey Ward; Jerry Kaplan
Regulation of iron acquisition and storage: consequences for iron-linked disorders.
Nature reviews. Molecular cell biology 2008;9(1):72-81.
2007: Ivana De Domenico; Michael B Vaughn; Donghoon Yoon; James P Kushner; Diane McVey Ward; Jerry Kaplan
Zebrafish as a model for defining the functional impact of mammalian ferroportin mutations.
Blood 2007;110(10):3780-3.
2007: Fudi Wang; Prasad N Paradkar; Angel O Custodio; Diane McVey Ward; Mark D Fleming; Dean R Campagna; Kristina A Roberts; Victor Boyartchuk; William F Dietrich; Jerry Kaplan; Nancy C Andrews
Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice.
Nature genetics 2007;39(8):1025-32.
2007: Ivana De Domenico; Diane McVey Ward; Jerry Kaplan
Hepcidin regulation: ironing out the details.
The Journal of clinical investigation 2007;117(7):1755-8.
2007: Ivana De Domenico; Diane McVey Ward; Charles Langelier; Michael B Vaughn; Elizabeta Nemeth; Wesley I Sundquist; Tomas Ganz; Giovanni Musci; Jerry Kaplan
The molecular mechanism of hepcidin-mediated ferroportin down-regulation.
Molecular biology of the cell 2007;18(7):2569-78.
2007: Ivana De Domenico; Diane McVey Ward; Maria Carmela Bonaccorsi di Patti; Suh Young Jeong; Samuel David; Giovanni Musci; Jerry Kaplan
Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI-ceruloplasmin.
The EMBO journal 2007;26(12):2823-31.
2007: Irene E Zohn; Ivana De Domenico; Andrew Pollock; Diane McVey Ward; Jessica F Goodman; Xiayun Liang; Amaru J Sanchez; Lee Niswander; Jerry Kaplan
The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease.
Blood 2007;109(10):4174-80.
2007: Ivana De Domenico; Diane McVey Ward; Giovanni Musci; Jerry Kaplan
Evidence for the multimeric structure of ferroportin.
Blood 2007;109(5):2205-9.
2006: Ivana De Domenico; Michael B Vaughn; Liangtao Li; Dustin Bagley; Giovanni Musci; Diane McVey Ward; Jerry Kaplan
Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome.
The EMBO journal 2006;25(22):5396-404.
2006: Sandra R Davis-Kaplan; Mark A Compton; Andrew R Flannery; Diane McVey Ward; Jerry Kaplan; Tom H Stevens; Laurie A Graham
PKR1 encodes an assembly factor for the yeast V-type ATPase.
The Journal of biological chemistry 2006;281(42):32025-35.
2006: Charles Langelier; Uta K von Schwedler; Robert D Fisher; Ivana De Domenico; Paul L White; Christopher P Hill; Jerry Kaplan; Diane Ward; Wesley I Sundquist
Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release.
Journal of virology 2006;80(19):9465-80.
2006: Attila Kumánovics; Katherine E Poruk; Katharine A Osborn; Diane McVey Ward; Jerry Kaplan
YKE4 (YIL023C) encodes a bidirectional zinc transporter in the endoplasmic reticulum of Saccharomyces cerevisiae.
The Journal of biological chemistry 2006;281(32):22566-74.
2006: Ivana De Domenico; Diane McVey Ward; Elizabeta Nemeth; Tomas Ganz; Elena Corradini; Francesca Ferrara; Giovanni Musci; Antonello Pietrangelo; Jerry Kaplan
Molecular and clinical correlates in iron overload associated with mutations in ferroportin.
Haematologica 2006;91(8):1092-5.
2006: Jerry Kaplan; Diane McVey Ward; Robert J Crisp; Caroline C Philpott
Iron-dependent metabolic remodeling in S. cerevisiae.
Biochimica et biophysica acta 2006;1763(7):646-51.
2006: Robert J Crisp; Erika Adkins Scholl; Emily Kimmel; Jerry Kaplan
Recruitment of Tup1p and Cti6p regulates heme-deficient expression of Aft1p target genes.
The EMBO journal 2006;25(3):512-21.
2006: Ivana De Domenico; Diane McVey Ward; Giovanni Musci; Jerry Kaplan
Iron overload due to mutations in ferroportin.
Haematologica 2006;91(1):92-5.
2006: Elizabeta Nemeth; Gloria C Preza; Chun-Ling Jung; Jerry Kaplan; Alan J Waring; Tomas Ganz
The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study.
Blood 2006;107(1):328-33.
2005: Ivana De Domenico; Diane McVey Ward; Elizabeta Nemeth; Michael B Vaughn; Giovanni Musci; Tomas Ganz; Jerry Kaplan
The molecular basis of ferroportin-linked hemochromatosis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(25):8955-60.
2005: Maria Rosa Felice; Ivana De Domenico; Liangtao Li; Diane McVey Ward; Beatrix Bartok; Giovanni Musci; Jerry Kaplan
Post-transcriptional regulation of the yeast high affinity iron transport system.
The Journal of biological chemistry 2005;280(23):22181-90.
2005: Diane McVey Ward; Michael B Vaughn; Shelly L Shiflett; Paul L White; Amanda L Pollock; Joshua Hill; Rachel Schnegelberger; Wesley I Sundquist; Jerry Kaplan
The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells.
The Journal of biological chemistry 2005;280(11):10548-55.
2004: Elizabeta Nemeth; Marie S Tuttle; Julie Powelson; Michael B Vaughn; Adriana Donovan; Diane McVey Ward; Tomas Ganz; Jerry Kaplan
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization.
Science (New York, N.Y.) 2004;306(5704):2090-3.
2004: Shelly L Shiflett; Michael B Vaughn; Dinh Huynh; Jerry Kaplan; Diane McVey Ward
Bph1p, the Saccharomyces cerevisiae homologue of CHS1/beige, functions in cell wall formation and protein sorting.
Traffic (Copenhagen, Denmark) 2004;5(9):700-10.
2004: Liangtao Li; Jerry Kaplan
A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism.
The Journal of biological chemistry 2004;279(32):33653-61.
2004: Opal S. Chen; Robert J Crisp; Martin Valachovic; Martin Bard; Dennis R Winge; Jerry Kaplan
Transcription of the yeast iron regulon does not respond directly to iron but rather to iron-sulfur cluster biosynthesis.
The Journal of biological chemistry 2004;279(28):29513-8.
2004: Z Leah Harris; Sandra R Davis-Kaplan; Jonathan D Gitlin; Jerry Kaplan
A fungal multicopper oxidase restores iron homeostasis in aceruloplasminemia.
Blood 2004;103(12):4672-3.
2004: Shelly L Shiflett; Diane McVey Ward; Dinh Huynh; Michael B Vaughn; Jennifer C Simmons; Jerry Kaplan
Characterization of Vta1p, a class E Vps protein in Saccharomyces cerevisiae.
The Journal of biological chemistry 2004;279(12):10982-90.
2004: Sandra R Davis-Kaplan; Diane McVey Ward; Shelly L Shiflett; Jerry Kaplan
Genome-wide analysis of iron-dependent growth reveals a novel yeast gene required for vacuolar acidification.
The Journal of biological chemistry 2004;279(6):4322-9.
2003: Robert J Crisp; Annette Pollington; Charles Galea; Shulamit Jaron; Yuko Yamaguchi-Iwai; Jerry Kaplan
Inhibition of heme biosynthesis prevents transcription of iron uptake genes in yeast.
The Journal of biological chemistry 2003;278(46):45499-506.
2003: Liangtao Li; Christopher D Vulpe; Jerry Kaplan
Functional studies of hephaestin in yeast: evidence for multicopper oxidase activity in the endocytic pathway.
The Biochemical journal 2003;375(Pt 3):793-8.
2003: Uta K von Schwedler; Melissa Stuchell; Barbara Müller; Diane McVey Ward; Hyo-Young Chung; Eiji Morita; Hubert E Wang; Thaylon Davis; Gong-Ping He; Daniel M Cimbora; Anna Scott; Hans-Georg Kräusslich; Jerry Kaplan; Scott G Morham; Wesley I Sundquist
The protein network of HIV budding.
Cell 2003;114(6):701-13.
2003: Diane McVey Ward; Shelly L Shiflett; Dinh Huynh; Michael B Vaughn; Glenn D Prestwich; Jerry Kaplan
Use of expression constructs to dissect the functional domains of the CHS/beige protein: identification of multiple phenotypes.
Traffic (Copenhagen, Denmark) 2003;4(6):403-15.
2003: Mark S Tuttle; Derek Radisky; Liangtao Li; Jerry Kaplan
A dominant allele of PDR1 alters transition metal resistance in yeast.
The Journal of biological chemistry 2003;278(2):1273-80.
2002: Opal S. Chen; Shawn Hemenway; Jerry Kaplan
Genetic analysis of iron citrate toxicity in yeast: implications for mammalian iron homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16922-7.
2002: Jerry Kaplan
Mechanisms of cellular iron acquisition: another iron in the fire.
Cell 2002;111(5):603-6.
2002: Jerry Kaplan
Strategy and tactics in the evolution of iron acquisition.
Seminars in hematology 2002;39(4):219-26.
2002: Opal S. Chen; Shawn Hemenway; Jerry Kaplan
Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12321-6.
2002: Diane McVey Ward; Shelly L Shiflett; Jerry Kaplan
Chediak-Higashi syndrome: a clinical and molecular view of a rare lysosomal storage disorder.
Current molecular medicine 2002;2(5):469-77.
2002: Shelly L Shiflett; Jerry Kaplan; Diane McVey Ward
Chediak-Higashi Syndrome: a rare disorder of lysosomes and lysosome related organelles.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2002;15(4):251-7.
2002: Jerry Kaplan
Spinocerebellar ataxias due to mitochondrial defects.
Neurochemistry international 2002;40(6):553-7.
2002: Anthony Van Ho; Diane McVey Ward; Jerry Kaplan
Transition metal transport in yeast.
Annual review of microbiology 2002;56():237-61.
2001: Opal S. Chen; Jerry Kaplan
YFH1-mediated iron homeostasis is independent of mitochondrial respiration.
FEBS letters 2001;509(1):131-4.
2001: Orly Ardon; H Bussey; Caroline C Philpott; Diane McVey Ward; Sandra R Davis-Kaplan; S Verroneau; B Jiang; Jerry Kaplan
Identification of a Candida albicans ferrichrome transporter and its characterization by expression in Saccharomyces cerevisiae.
The Journal of biological chemistry 2001;276(46):43049-55.
2001: Liangtao Li; Opal S. Chen; Diane McVey Ward; Jerry Kaplan
CCC1 is a transporter that mediates vacuolar iron storage in yeast.
The Journal of biological chemistry 2001;276(31):29515-9.
2001: Diane McVey Ward; Derek Radisky; M A Scullion; Mark S Tuttle; Michael B Vaughn; Jerry Kaplan
hVPS41 is expressed in multiple isoforms and can associate with vesicles through a RING-H2 finger motif.
Experimental cell research 2001;267(1):126-34.
2001: Liangtao Li; Jerry Kaplan
The yeast gene MSC2, a member of the cation diffusion facilitator family, affects the cellular distribution of zinc.
The Journal of biological chemistry 2001;276(7):5036-43.
2000: Diane McVey Ward; Gillian M Griffiths; Jane C Stinchcombe; Jerry Kaplan
Analysis of the lysosomal storage disease Chediak-Higashi syndrome.
Traffic (Copenhagen, Denmark) 2000;1(11):816-22.
2000: W Yang; C Li; Diane McVey Ward; Jerry Kaplan; S L Mansour
Defective organellar membrane protein trafficking in Ap3b1-deficient cells.
Journal of cell science 2000;113 ( Pt 22)():4077-86.
2000: Diane McVey Ward; Jonathan Pevsner; M A Scullion; Michael B Vaughn; Jerry Kaplan
Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages.
Molecular biology of the cell 2000;11(7):2327-33.
2000: Cheol-Won Yun; Tracey Ferea; Jared Rashford; O Ardon; Patrick O Brown; David Botstein; Jerry Kaplan; Caroline C Philpott
Desferrioxamine-mediated iron uptake in Saccharomyces cerevisiae. Evidence for two pathways of iron uptake.
The Journal of biological chemistry 2000;275(14):10709-15.
2000: Opal S. Chen; Jerry Kaplan
CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation.
The Journal of biological chemistry 2000;275(11):7626-32.
1999: Derek Radisky; M C Babcock; Jerry Kaplan
The yeast frataxin homologue mediates mitochondrial iron efflux. Evidence for a mitochondrial iron cycle.
The Journal of biological chemistry 1999;274(8):4497-9.
1999: Derek Radisky; Jerry Kaplan
Regulation of transition metal transport across the yeast plasma membrane.
The Journal of biological chemistry 1999;274(8):4481-4.
1998: Derek Radisky; Jerry Kaplan
Iron in cytosolic ferritin can be recycled through lysosomal degradation in human fibroblasts.
The Biochemical journal 1998;336 ( Pt 1)():201-5.
1998: Sandra R Davis-Kaplan; CC Askwith; A C Bengtzen; Derek Radisky; Jerry Kaplan
Chloride is an allosteric effector of copper assembly for the yeast multicopper oxidase Fet3p: an unexpected role for intracellular chloride channels.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13641-5.
1998: CC Askwith; Jerry Kaplan
Site-directed mutagenesis of the yeast multicopper oxidase Fet3p.
The Journal of biological chemistry 1998;273(35):22415-9.
1998: Liangtao Li; Jerry Kaplan
Defects in the yeast high affinity iron transport system result in increased metal sensitivity because of the increased expression of transporters with a broad transition metal specificity.
The Journal of biological chemistry 1998;273(35):22181-7.
1998: CC Askwith; Jerry Kaplan
Iron and copper transport in yeast and its relevance to human disease.
Trends in biochemical sciences 1998;23(4):135-8.
1997: Charles M Perou; J D Leslie; W Green; Liangtao Li; Diane McVey Ward; Jerry Kaplan
The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein.
The Journal of biological chemistry 1997;272(47):29790-4.
1997: Liangtao Li; Jerry Kaplan
Characterization of two homologous yeast genes that encode mitochondrial iron transporters.
The Journal of biological chemistry 1997;272(45):28485-93.
1997: D M Ward; J D Leslie; Jerry Kaplan
Homotypic lysosome fusion in macrophages: analysis using an in vitro assay.
The Journal of cell biology 1997;139(3):665-73.
1997: M Babcock; D de Silva; R Oaks; Sandra R Davis-Kaplan; S Jiralerspong; L Montermini; Massimo Pandolfo; Jerry Kaplan
Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin.
Science (New York, N.Y.) 1997;276(5319):1709-12.
1997: Charles M Perou; Robert J Pryor; T P Naas; Jerry Kaplan
The bg allele mutation is due to a LINE1 element retrotransposition.
Genomics 1997;42(2):366-8.
1997: D de Silva; Sandra R Davis-Kaplan; J Fergestad; Jerry Kaplan
Purification and characterization of Fet3 protein, a yeast homologue of ceruloplasmin.
The Journal of biological chemistry 1997;272(22):14208-13.
1997: Derek Radisky; W B Snyder; Scott D Emr; Jerry Kaplan
Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(11):5662-6.
1997: Charles M Perou; A Perchellet; T Jago; Robert J Pryor; Jerry Kaplan; M J Justice
Comparative mapping in the beige-satin region of mouse chromosome 13.
Genomics 1997;39(2):136-46.
1997: CC Askwith; Jerry Kaplan
An oxidase-permease-based iron transport system in Schizosaccharomyces pombe and its expression in Saccharomyces cerevisiae.
The Journal of biological chemistry 1997;272(1):401-5.
1996: T Taraska; D M Ward; Richard S Ajioka; P B Wyrick; Sandra R Davis-Kaplan; Caroyn H Davis; Jerry Kaplan
The late chlamydial inclusion membrane is not derived from the endocytic pathway and is relatively deficient in host proteins.
Infection and immunity 1996;64(9):3713-27.
1996: Liangtao Li; Jerry Kaplan
Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue.
The Journal of biological chemistry 1996;271(28):16927-33.
1996: Charles M Perou; KJ Moore; DL Nagle; D J Misumi; EA Woolf; S H McGrail; LM Holmgren; T H Brody; BJ Dussault; C A Monroe; Geoffrey Duyk; R J Pryor; Liangtao Li; M J Justice; Jerry Kaplan
Identification of the murine beige gene by YAC complementation and positional cloning.
Nature genetics 1996;13(3):303-8.
1996: Charles M Perou; M J Justice; R J Pryor; Jerry Kaplan
Complementation of the beige mutation in cultured cells by episomally replicating murine yeast artificial chromosomes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(12):5905-9.
1996: CC Askwith; D de Silva; Jerry Kaplan
Molecular biology of iron acquisition in Saccharomyces cerevisiae.
Molecular microbiology 1996;20(1):27-34.
1996: Jerry Kaplan; T V O'Halloran
Iron metabolism in eukaryotes: Mars and Venus at it again.
Science (New York, N.Y.) 1996;271(5255):1510-2.
1996: D M de Silva; CC Askwith; Jerry Kaplan
Molecular mechanisms of iron uptake in eukaryotes.
Physiological reviews 1996;76(1):31-47.
1995: D M Ward; Charles M Perou; M Lloyd; Jerry Kaplan
"Synchronized" endocytosis and intracellular sorting in alveolar macrophages: the early sorting endosome is a transient organelle.
The Journal of cell biology 1995;129(5):1229-40.
1995: D M De Silva; CC Askwith; D Eide; Jerry Kaplan
The FET3 gene product required for high affinity iron transport in yeast is a cell surface ferroxidase.
The Journal of biological chemistry 1995;270(3):1098-101.
1994: I Jordan; Jerry Kaplan
The mammalian transferrin-independent iron transport system may involve a surface ferrireductase activity.
The Biochemical journal 1994;302 ( Pt 3)():875-9.
1994: CC Askwith; D Eide; A Van Ho; Philip S Bernard; Liangtao Li; Sandra R Davis-Kaplan; D M Sipe; Jerry Kaplan
The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake.
Cell 1994;76(2):403-10.
1994: Andrew Dancis; Daniel S Yuan; David Haile; CC Askwith; D Eide; C Moehle; Jerry Kaplan; Richard D Klausner
Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport.
Cell 1994;76(2):393-402.
1993: Charles M Perou; Jerry Kaplan
Complementation analysis of Chediak-Higashi syndrome: the same gene may be responsible for the defect in all patients and species.
Somatic cell and molecular genetics 1993;19(5):459-68.
1993: Charles M Perou; Jerry Kaplan
Chediak-Higashi syndrome is not due to a defect in microtubule-based lysosomal mobility.
Journal of cell science 1993;106 ( Pt 1)():99-107.
1992: D Eide; Sandra R Davis-Kaplan; I Jordan; D Sipe; Jerry Kaplan
Regulation of iron uptake in Saccharomyces cerevisiae. The ferrireductase and Fe(II) transporter are regulated independently.
The Journal of biological chemistry 1992;267(29):20774-81.
1991: Saundra S Buys; C B Martin; M Eldridge; James P Kushner; Jerry Kaplan
Iron absorption in hypotransferrinemic mice.
Blood 1991;78(12):3288-90.
1991: Jerry Kaplan; I Jordan; Anne B Sturrock
Regulation of the transferrin-independent iron transport system in cultured cells.
The Journal of biological chemistry 1991;266(5):2997-3004.
1990: D M Ward; D P Hackenyos; Sandra R Davis-Kaplan; Jerry Kaplan
Inhibition of late endosome-lysosome fusion: studies on the mechanism by which isotonic-K+ buffers alter intracellular ligand movement.
Journal of cellular physiology 1990;145(3):522-30.
1990: D M Ward; Jerry Kaplan
The rate of internalization of different receptor-ligand complexes in alveolar macrophages is receptor-specific.
The Biochemical journal 1990;270(2):369-74.
1990: D M Ward; D P Hackenyos; Jerry Kaplan
Fusion of sequentially internalized vesicles in alveolar macrophages.
The Journal of cell biology 1990;110(4):1013-22.
1990: Anne B Sturrock; J Alexander; J Lamb; C M Craven; Jerry Kaplan
Characterization of a transferrin-independent uptake system for iron in HeLa cells.
The Journal of biological chemistry 1990;265(6):3139-45.
1989: Saundra S Buys; J M Novak; L H Gren; Jerry Kaplan
Effect of volume and pH on surface receptor number in macrophages.
Journal of cellular physiology 1989;140(2):371-8.
1989: D M Ward; Richard S Ajioka; Jerry Kaplan
Cohort movement of different ligands and receptors in the intracellular endocytic pathway of alveolar macrophages.
The Journal of biological chemistry 1989;264(14):8164-70.
1988: J M Novak; Peter M Cala; D M Ward; Saundra S Buys; Jerry Kaplan
Regulatory volume decrease in alveolar macrophages: cation loss is not correlated with changes in membrane recycling.
Journal of cellular physiology 1988;137(2):243-50.
1988: J M Novak; D M Ward; Saundra S Buys; Jerry Kaplan
Effect of hypo-osmotic incubation on membrane recycling.
Journal of cellular physiology 1988;137(2):235-42.
1987: Saundra S Buys; L H Gren; Jerry Kaplan
Phorbol esters and calcium ionophores inhibit internalization and accelerate recycling of receptors in macrophages.
The Journal of biological chemistry 1987;262(27):12970-6.