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Johanne Kaplan

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Sambasiva P Rao; Bruce L Roberts; Jose Sancho; Peter B Severy; Srinivas Shankara; Timothy Weeden; Paula M Boutin; Juanita Campos-Rivera; Johanne M Kaplan
Human peripheral blood mononuclear cells exhibit heterogeneous CD52 expression levels and show differential sensitivity to alemtuzumab mediated cytolysis.
William M Siders; Jacqueline Shields; Carrie Garron; Yanping Hu; Paula Boutin; Srinivas Shankara; William Weber; Bruce Roberts; Johanne M Kaplan
Involvement of neutrophils and natural killer cells in the anti-tumor activity of alemtuzumab in xenograft tumor models.
Yanping Hu; Michael J Turner; Jacqueline Shields; Matthew S Gale; Elizabeth Hutto; Bruce L Roberts; William M Siders; Johanne M Kaplan
Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model.

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2012: Sambasiva P Rao; Bruce L Roberts; Jose Sancho; Peter B Severy; Srinivas Shankara; Timothy Weeden; Paula M Boutin; Juanita Campos-Rivera; Johanne M Kaplan
Human peripheral blood mononuclear cells exhibit heterogeneous CD52 expression levels and show differential sensitivity to alemtuzumab mediated cytolysis.
PloS one 2012;7(6):e39416.
2010: William M Siders; Jacqueline Shields; Carrie Garron; Yanping Hu; Paula Boutin; Srinivas Shankara; William Weber; Bruce Roberts; Johanne M Kaplan
Involvement of neutrophils and natural killer cells in the anti-tumor activity of alemtuzumab in xenograft tumor models.
Leukemia & lymphoma 2010;51(7):1293-304.
2009: Yanping Hu; Michael J Turner; Jacqueline Shields; Matthew S Gale; Elizabeth Hutto; Bruce L Roberts; William M Siders; Johanne M Kaplan
Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model.
Immunology 2009;128(2):260-70.
2004: Johanne M Kaplan
New cancer vaccine approaches.
Drugs of today (Barcelona, Spain : 1998) 2004;40(11):913-29.
2004: Michael A Perricone; Karen A Smith; Kirsten A Claussen; Malinda S Plog; Donna M Hempel; Bruce L Roberts; Judith A St George; Johanne M Kaplan
Enhanced efficacy of melanoma vaccines in the absence of B lymphocytes.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(4):273-81.
2003: William M Siders; Kristin L Vergilis; Carrie Johnson; Jacqueline Shields; Johanne M Kaplan
Induction of specific antitumor immunity in the mouse with the electrofusion product of tumor cells and dendritic cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(4):498-505.
2002: William M Siders; Kristin Vergillis; Carrie Johnson; Ronald K Scheule; Johanne M Kaplan
Tumor treatment with complexes of cationic lipid and noncoding plasmid DNA results in the induction of cytotoxic T cells and systemic tumor elimination.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(4):519-27.
2002: Carla A Lawendowski; Gina LaCorcia; Yin Yin Huang; G Joseph Franklin; Johanne M Kaplan; Bruce L Roberts; Charles A Nicolette
Solid-phase epitope recovery: a high throughput method for antigen identification and epitope optimization.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2414-21.
2000: Abraham Scaria; Jennifer A Sullivan; Judith A St George; Johanne M Kaplan; Michael Lukason; James E Morris; Malinda S Plog; Charles A Nicolette; Richard J Gregory; Samuel C Wadsworth
Adenoviral vector expressing ICP47 inhibits adenovirus-specific cytotoxic T lymphocytes in nonhuman primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(5):505-14.
2000: Michael A Perricone; D D Rees; C R Sacks; Karen A Smith; Johanne M Kaplan; Judith A St George
Inhibitory effect of cystic fibrosis sputum on adenovirus-mediated gene transfer in cultured epithelial cells.
Human gene therapy 2000;11(14):1997-2008.
2000: Michael A Perricone; Kirsten A Claussen; Karen A Smith; Johanne M Kaplan; S Piraino; Srinivas Shankara; Bruce L Roberts
Immunogene therapy for murine melanoma using recombinant adenoviral vectors expressing melanoma-associated antigens.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(3):275-84.
1999: Johanne M Kaplan; Q Yu; S T Piraino; SE Pennington; Srinivas Shankara; LA Woodworth; Bruce L Roberts
Induction of antitumor immunity with dendritic cells transduced with adenovirus vector-encoding endogenous tumor-associated antigens.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):699-707.
1999: Johanne M Kaplan; Donna Armentano; Abraham Scaria; LA Woodworth; SE Pennington; Samuel C Wadsworth; AE Smith; Richard J Gregory
Novel role for E4 region genes in protection of adenovirus vectors from lysis by cytotoxic T lymphocytes.
Journal of virology 1999;73(5):4489-92.
1998: Abraham Scaria; Judith A St George; Canwen Jiang; Johanne M Kaplan; Samuel C Wadsworth; Richard J Gregory
Adenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium.
Journal of virology 1998;72(9):7302-9.
1998: Johanne M Kaplan; SE Pennington; Judith A St George; LA Woodworth; A Fasbender; John Marshall; Seng Cheng; Samuel C Wadsworth; Richard J Gregory; AE Smith
Potentiation of gene transfer to the mouse lung by complexes of adenovirus vector and polycations improves therapeutic potential.
Human gene therapy 1998;9(10):1469-79.
1997: Samuel C Wadsworth; H Zhou; AE Smith; Johanne M Kaplan
Adenovirus vector-infected cells can escape adenovirus antigen-specific cytotoxic T-lymphocyte killing in vivo.
Journal of virology 1997;71(7):5189-96.
1997: Johanne M Kaplan; AE Smith
Transient immunosuppression with deoxyspergualin improves longevity of transgene expression and ability to readminister adenoviral vector to the mouse lung.
Human gene therapy 1997;8(9):1095-104.
1997: Abraham Scaria; Judith A St George; Richard J Gregory; R J Noelle; Samuel C Wadsworth; AE Smith; Johanne M Kaplan
Antibody to CD40 ligand inhibits both humoral and cellular immune responses to adenoviral vectors and facilitates repeated administration to mouse airway.
Gene therapy 1997;4(6):611-7.
1997: Ronald K Scheule; Judith A St George; Rebecca G Bagley; John Marshall; Johanne M Kaplan; Geoffrey Y Akita; KX Wang; ER Lee; DJ Harris; Canwen Jiang; Nelson S Yew; AE Smith; Seng Cheng
Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung.
Human gene therapy 1997;8(6):689-707.
1997: Ruth J Mcdonald; Michael Lukason; Otto G Raabe; D R Canfield; E A Burr; Johanne M Kaplan; Samuel C Wadsworth; Judith A St George
Safety of airway gene transfer with Ad2/CFTR2: aerosol administration in the nonhuman primate.
Human gene therapy 1997;8(4):411-22.
1997: Tim E. Sparer; SG Wynn; D J Clark; Johanne M Kaplan; L M Cardoza; Samuel C Wadsworth; AE Smith; Linda R Gooding
Generation of cytotoxic T lymphocytes against immunorecessive epitopes after multiple immunizations with adenovirus vectors is dependent on haplotype.
Journal of virology 1997;71(3):2277-84.
1997: Johanne M Kaplan; Donna Armentano; Tim E. Sparer; SG Wynn; P A Peterson; Samuel C Wadsworth; K K Couture; SE Pennington; Judith A St George; Linda R Gooding; AE Smith
Characterization of factors involved in modulating persistence of transgene expression from recombinant adenovirus in the mouse lung.
Human gene therapy 1997;8(1):45-56.
1996: Johanne M Kaplan; Judith A St George; SE Pennington; L D Keyes; R P Johnson; Samuel C Wadsworth; AE Smith
Humoral and cellular immune responses of nonhuman primates to long-term repeated lung exposure to Ad2/CFTR-2.
Gene therapy 1996;3(2):117-27.
1996: Judith A St George; SE Pennington; Johanne M Kaplan; P A Peterson; L J Kleine; AE Smith; Samuel C Wadsworth
Biological response of nonhuman primates to long-term repeated lung exposure to Ad2/CFTR-2.
Gene therapy 1996;3(2):103-16.