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John Kappler

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Amy S McKee; Michael W Munks; Matthew A Burchill; Rachel S Friedman; Jordan Jacobelli; Lei Jin; John W Kappler; Philippa Marrack
Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells.
Anatoly V Rubtsov; Kira Rubtsova; John W Kappler; Philippa Marrack
TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice.
Bernard Collins; James Hagman; Philippa Marrack; James Scott-Browne; Janice White; Eric T Clambey; John W Kappler
Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line.

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2013: Amy S McKee; Michael W Munks; Matthew A Burchill; Rachel S Friedman; Jordan Jacobelli; Lei Jin; John W Kappler; Philippa Marrack
Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(12):E1122-31.
2013: Anatoly V Rubtsov; Kira Rubtsova; John W Kappler; Philippa Marrack
TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice.
Immunologic research 2013;55(1-3):210-6.
2013: Bernard Collins; James Hagman; Philippa Marrack; James Scott-Browne; Janice White; Eric T Clambey; John W Kappler
Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line.
European journal of immunology 2013;43(2):521-32.
2013: Megan K L Macleod; Alexandria David; Niyun Jin; John W Kappler; Laura Noges; Jieru Wang; Philippa Marrack
Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza a virus that expresses an altered nucleoprotein sequence.
PloS one 2013;8(4):e61775.
2013: Eric T Clambey; Bernard Collins; Alexandria David; Jens Eberlein; John W Kappler; Mary H Young; Philippa Marrack
The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells.
PloS one 2013;8(2):e57435.
2012: Lei Yin; Frances Crawford; John W Kappler; Philippa Marrack; Shaodong Dai
T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(45):18517-22.
2012: Kimberly R Jordan; John W Kappler; Brandon L Moore; Jonathan D Buhrman; Dexiang Gao; Jonathan Sprague; Jill E Slansky
TCR hypervariable regions expressed by T cells that respond to effective tumor vaccines.
Cancer immunology, immunotherapy : CII 2012;61(10):1627-38.
2012: Philippa Marrack; John W Kappler
Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases?
Cold Spring Harbor perspectives in medicine 2012;2(9):a007765.
2012: K Christopher Garcia; John W Kappler; Jarrett J Adams; Michael E Birnbaum; Laurent Gapin; James P Scott-Browne; Philippa Marrack
A closer look at TCR germline recognition.
Immunity 2012;36(6):887-8; author reply 889-90.
2011: Li Zhang; John W Kappler; Aaron Michels; Brian D Stadinski; George S Eisenbarth
Immunization with an insulin peptide-MHC complex to prevent type 1 diabetes of NOD mice.
Diabetes/metabolism research and reviews 2011;27(8):784-9.
2011: James P Scott-Browne; Mary H Young; Frances Crawford; John W Kappler; Philippa Marrack; Laurent Gapin
Evolutionarily conserved features contribute to αβ T cell receptor specificity.
Immunity 2011;35(4):526-35.
2011: Natalie A Bowerman; Michael T Falta; John W Kappler; Douglas G Mack; Andrew P Fontenot
Mutagenesis of beryllium-specific TCRs suggests an unusual binding topology for antigen recognition.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(7):3694-703.
2011: Anatoly V Rubtsov; Kira Rubtsova; Richard T Meehan; Aryeh Fischer; Joann Z Gillis; John W Kappler; Philippa Marrack
Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity.
Blood 2011;118(5):1305-15.
2011: Lei Yin; Frances Crawford; Shaodong Dai; Eric S Huseby; Philippa Marrack; Clamencia Pinilla; Kira Rubtsova; James Scott-Browne; John W Kappler
A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers.
Immunity 2011;35(1):23-33.
2011: Megan K L MacLeod; Alexandria David; Amy S McKee; Frances Crawford; John W Kappler; Philippa Marrack
Memory CD4 T cells that express CXCR5 provide accelerated help to B cells.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(5):2889-96.
2010: Xia Hong; Jianye Zang; Janice White; Chao Wang; Cheol-Ho Pan; Rui Zhao; Robert C Murphy; Shaodong Dai; Peter Henson; John W Kappler; James Hagman; Gongyi Zhang
Interaction of JMJD6 with single-stranded RNA.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(33):14568-72.
2010: Brian D Stadinski; Li Zhang; Frances Crawford; Philippa Marrack; George S Eisenbarth; John W Kappler
Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(24):10978-83.
2010: Michael T Falta; Natalie A Bowerman; Shaodong Dai; John W Kappler; Andrew P Fontenot
Linking genetic susceptibility and T cell activation in beryllium-induced disease.
Proceedings of the American Thoracic Society 2010;7(2):126-9.
2010: Anatoly V Rubtsov; Kira Rubtsova; John W Kappler; Philippa Marrack
Genetic and hormonal factors in female-biased autoimmunity.
Autoimmunity reviews 2010;9(7):494-8.
2010: Kimberly R Jordan; Rachel H McMahan; Charles B Kemmler; John W Kappler; Jill E Slansky
Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(10):4652-7.
2010: Brian D Stadinski; Thomas Delong; Nichole Reisdorph; Richard Reisdorph; Roger L Powell; Michael Armstrong; Jon D Piganelli; Gene Barbour; Brenda Bradley; Frances Crawford; Philippa Marrack; Sushil K Mahata; John W Kappler; Kathryn Haskins
Chromogranin A is an autoantigen in type 1 diabetes.
Nature immunology 2010;11(3):225-31.
2010: Amy S McKee; Megan K L MacLeod; John W Kappler; Philippa Marrack
Immune mechanisms of protection: can adjuvants rise to the challenge?
BMC biology 2010;8():37.
2009: Yibing Wang; Dean Becker; Tibor Vass; Janice White; Philippa Marrack; John W Kappler
A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling.
PLoS biology 2009;7(12):e1000253.
2009: Kira Rubtsova; James P Scott-Browne; Frances Crawford; Shaodong Dai; Philippa Marrack; John W Kappler
Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(19):7951-6.
2009: James P Scott-Browne; Janice White; John W Kappler; Laurent Gapin; Philippa Marrack
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection.
Nature 2009;458(7241):1043-6.
2009: Anthony L Desbien; John W Kappler; Philippa Marrack
The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5663-8.
2009: Kimberly R Jordan; Fran Crawford; John W Kappler; Jill E Slansky
Vaccination of mice with baculovirus-infected insect cells expressing antigenic proteins.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2009;Chapter 2():Unit 2.15.
2009: Megan K L MacLeod; Eric T Clambey; John W Kappler; Philippa Marrack
CD4 memory T cells: what are they and what can they do?
Seminars in immunology 2009;21(2):53-61.
2009: Michael F J Bassetti; Janice White; John W Kappler; Philippa Marrack
Transgenic Bcl-3 slows T cell proliferation.
International immunology 2009;21(4):339-48.
2008: Eric T Clambey; Janice White; John W Kappler; Philippa Marrack
Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):12997-3002.
2008: Shaodong Dai; Frances Crawford; Philippa Marrack; John W Kappler
The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11893-7.
2008: Amy S McKee; Megan MacLeod; Janice White; Frances Crawford; John W Kappler; Philippa Marrack
Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses.
International immunology 2008;20(5):659-69.
2008: Philippa Marrack; Kira Rubtsova; James Scott-Browne; John W Kappler
T cell receptor specificity for major histocompatibility complex proteins.
Current opinion in immunology 2008;20(2):203-7.
2008: Shaodong Dai; Eric S Huseby; Kira Rubtsova; James Scott-Browne; Frances Crawford; Whitney A Macdonald; Philippa Marrack; John W Kappler
Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity 2008;28(3):324-34.
2008: Eric S Huseby; John W Kappler; Philippa Marrack
Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains.
Molecular immunology 2008;45(3):599-606.
2008: Philippa Marrack; James P Scott-Browne; Shaodong Dai; Laurent Gapin; John W Kappler
Evolutionarily conserved amino acids that control TCR-MHC interaction.
Annual review of immunology 2008;26():171-203.
2008: Kimberly R Jordan; Rachel H McMahan; Jason Z Oh; Matthew R Pipeling; Drew M Pardoll; Ross M Kedl; John W Kappler; Jill E Slansky
Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):188-97.
2007: Trine N Jorgensen; Amy McKee; Michael Wang; Ella Kushnir; Janice White; Yosef Refaeli; John W Kappler; Philippa Marrack
Bim and Bcl-2 mutually affect the expression of the other in T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):3417-24.
2007: Eric T Clambey; John W Kappler; Philippa Marrack
CD8 T cell clonal expansions & aging: a heterogeneous phenomenon with a common outcome.
Experimental gerontology 2007;42(5):407-11.
2007: Fred W Peyerl; Shaodong Dai; G A Murphy; F Crawford; J White; Philippa Marrack; John W Kappler
Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex.
Cell death and differentiation 2007;14(3):447-52.
2006: Xinqi Liu; Yanan Zhu; Shaodong Dai; Janice White; Fred W Peyerl; John W Kappler; Philippa Marrack
Bcl-xl does not have to bind Bax to protect T cells from death.
The Journal of experimental medicine 2006;203(13):2953-61.
2006: Eric S Huseby; Frances Crawford; Janice White; Philippa Marrack; John W Kappler
Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide.
Nature immunology 2006;7(11):1191-9.
2006: Richard A Willis; John W Kappler; Philippa Marrack
CD8 T cell competition for dendritic cells in vivo is an early event in activation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):12063-8.
2006: Jennifer M Robertson; Megan MacLeod; Vanessa S Marsden; John W Kappler; Philippa Marrack
Not all CD4+ memory T cells are long lived.
Immunological reviews 2006;211():49-57.
2006: Frances Crawford; Kimberly R Jordan; Brian Stadinski; Yibing Wang; Eric S Huseby; Philippa Marrack; Jill E Slansky; John W Kappler
Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands.
Immunological reviews 2006;210():156-70.
2006: Vanessa S Marsden; John W Kappler; Philippa Marrack
Homeostasis of the memory T cell pool.
International archives of allergy and immunology 2006;139(1):63-74.
2005: Eric T Boder; Jerome R Bill; Andrew W Nields; Philippa Marrack; John W Kappler
Yeast surface display of a noncovalent MHC class II heterodimer complexed with antigenic peptide.
Biotechnology and bioengineering 2005;92(4):485-91.
2005: Eric S Huseby; Janice White; Frances Crawford; Tibor Vass; Dean Becker; Clemencia Pinilla; Philippa Marrack; John W Kappler
How the T cell repertoire becomes peptide and MHC specific.
Cell 2005;122(2):247-60.
2005: Eric T Clambey; Linda F van Dyk; John W Kappler; Philippa Marrack
Non-malignant clonal expansions of CD8+ memory T cells in aged individuals.
Immunological reviews 2005;205():170-89.
2005: Yibing Wang; Anatoyla Rubtsov; Ryan Heiser; Janice White; Frances Crawford; Philippa Marrack; John W Kappler
Using a baculovirus display library to identify MHC class I mimotopes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(7):2476-81.
2004: Frances Crawford; Eric S Huseby; Janice White; Philippa Marrack; John W Kappler
Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library.
PLoS biology 2004;2(4):E90.
2004: Brian C Schaefer; John W Kappler; Abraham Kupfer; Philippa Marrack
Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(4):1004-9.
2003: Xinqi Liu; Shaodong Dai; Yanan Zhu; Philippa Marrack; John W Kappler
The structure of a Bcl-xL/Bim fragment complex: implications for Bim function.
Immunity 2003;19(3):341-52.
2003: Ross M Kedl; John W Kappler; Philippa Marrack
Epitope dominance, competition and T cell affinity maturation.
Current opinion in immunology 2003;15(1):120-7.
2002: Thomas C Mitchell; Teague Kent; David A Hildeman; Jeremy Bender; William A Rees; Ross M Kedl; Brad Swanson; John W Kappler; Philippa Marrack
Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival.
Annals of the New York Academy of Sciences 2002;975():114-31.
2002: Ross M Kedl; Brian C Schaefer; John W Kappler; Philippa Marrack
T cells down-modulate peptide-MHC complexes on APCs in vivo.
Nature immunology 2002;3(1):27-32.
2001: Brian C Schaefer; M L Schaefer; John W Kappler; Philippa Marrack; Ross M Kedl
Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo.
Cellular immunology 2001;214(2):110-22.
2001: Brian C Schaefer; Thomas C Mitchell; John W Kappler; Philippa Marrack
A novel family of retroviral vectors for the rapid production of complex stable cell lines.
Analytical biochemistry 2001;297(1):86-93.
2000: Teague Kent; Brian C Schaefer; David A Hildeman; Jeremy Bender; T Mitchell; John W Kappler; Philippa Marrack
Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling.
The Journal of experimental medicine 2000;191(6):915-26.
1999: Brian C Schaefer; Marti Ware; Philippa Marrack; Gary R Fanger; John W Kappler; Gary L Johnson; CR Monks
Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor.
Immunity 1999;11(4):411-21.
1997: Teague Kent; Philippa Marrack; John W Kappler; AT Vella
IL-6 rescues resting mouse T cells from apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):5791-6.
1997: J L Seibel; N Wilson; H Kozono; Philippa Marrack; John W Kappler
Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition.
The Journal of experimental medicine 1997;185(11):1919-27.
1997: AT Vella; T Mitchell; B Groth; Peter Linsley; J M Green; Craig Thompson; John W Kappler; Philippa Marrack
CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):4714-20.
1997: Abdel Rahim A Hamad; Philippa Marrack; John W Kappler
Transcytosis of staphylococcal superantigen toxins.
The Journal of experimental medicine 1997;185(8):1447-54.
1997: Eckard H Hamelmann; AT Vella; A Oshiba; John W Kappler; Philippa Marrack; Erwin W Gelfand
Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1350-5.
1997: C P Liu; W J Lin; M Huang; John W Kappler; Philippa Marrack
Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):616-21.
1996: C P Liu; John W Kappler; Philippa Marrack
Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage.
The Journal of experimental medicine 1996;184(5):1619-30.
1996: AT Vella; M T Scherer; L Schultz; John W Kappler; Philippa Marrack
B cells are not essential for peripheral T-cell tolerance.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):951-5.
1995: AT Vella; J E McCormack; Peter Linsley; John W Kappler; Philippa Marrack
Lipopolysaccharide interferes with the induction of peripheral T cell death.
Immunity 1995;2(3):261-70.
1994: Abdel Rahim A Hamad; A Herman; Philippa Marrack; John W Kappler
Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B.
The Journal of experimental medicine 1994;180(2):615-21.
1994: J P Donahue; N S Ricalton; C E Behrendt; C Rittershaus; S Calaman; Philippa Marrack; John W Kappler; Brian L Kotzin
Genetic analysis of low V beta 3 expression in humans.
The Journal of experimental medicine 1994;179(5):1701-6.
1994: G M Winslow; Philippa Marrack; John W Kappler
Processing and major histocompatibility complex binding of the MTV7 superantigen.
Immunity 1994;1(1):23-33.
1994: P Hugo; John W Kappler; Dale I Godfrey; Philippa Marrack
Thymic epithelial cell lines that mediate positive selection can also induce thymocyte clonal deletion.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):1022-31.
1994: Leszek Ignatowicz; John W Kappler; Philippa Marrack; M T Scherer
Identification of two V beta 7-specific viral superantigens.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):65-71.
1993: J E Callahan; John W Kappler; Philippa Marrack
Unexpected expansions of CD8-bearing cells in old mice.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):6657-69.
1993: Philippa Marrack; Leszek Ignatowicz; John W Kappler; J Boymel; J H Freed
Comparison of peptides bound to spleen and thymus class II.
The Journal of experimental medicine 1993;178(6):2173-83.
1993: P Hugo; John W Kappler; J E McCormack; Philippa Marrack
Fibroblasts can induce thymocyte positive selection in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10335-9.
1993: P Hugo; John W Kappler; Philippa Marrack
Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein?
Immunological reviews 1993;135():133-55.
1993: Philippa Marrack; G M Winslow; Y Choi; M Scherer; A Pullen; J White; John W Kappler
The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions.
Immunological reviews 1993;131():79-92.
1993: J White; A Pullen; K Choi; Philippa Marrack; John W Kappler
Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor.
The Journal of experimental medicine 1993;177(1):119-25.
1993: M T Scherer; Leszek Ignatowicz; G M Winslow; John W Kappler; Philippa Marrack
Superantigens: bacterial and viral proteins that manipulate the immune system.
Annual review of cell biology 1993;9():101-28.
1992: P Hugo; John W Kappler; Dale I Godfrey; Philippa Marrack
A cell line that can induce thymocyte positive selection.
Nature 1992;360(6405):679-82.
1992: G M Winslow; M T Scherer; John W Kappler; Philippa Marrack
Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a).
Cell 1992;71(5):719-30.
1992: Y Choi; Philippa Marrack; John W Kappler
Structural analysis of a mouse mammary tumor virus superantigen.
The Journal of experimental medicine 1992;175(3):847-52.
1992: John W Kappler; A Herman; J Clements; Philippa Marrack
Mutations defining functional regions of the superantigen staphylococcal enterotoxin B.
The Journal of experimental medicine 1992;175(2):387-96.
1991: A Herman; N Labrecque; Jacques Thibodeau; Philippa Marrack; John W Kappler; Rafick-Pierre Sekaly
Identification of the staphylococcal enterotoxin A superantigen binding site in the beta 1 domain of the human histocompatibility antigen HLA-DR.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):9954-8.
1991: Y Choi; John W Kappler; Philippa Marrack
A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus.
Nature 1991;350(6315):203-7.
1991: A Herman; John W Kappler; Philippa Marrack; A M Pullen
Superantigens: mechanism of T-cell stimulation and role in immune responses.
Annual review of immunology 1991;9():745-72.
1990: A M Pullen; T Wade; Philippa Marrack; John W Kappler
Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a.
Cell 1990;61(7):1365-74.
1990: J E Callahan; A Herman; John W Kappler; Philippa Marrack
Stimulation of B10.BR T cells with superantigenic staphylococcal toxins.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(7):2473-9.
1989: H G Burgert; J White; H U Weltzien; Philippa Marrack; John W Kappler
Reactivity of V beta 17a+ CD8+ T cell hybrids. Analysis using a new CD8+ T cell fusion partner.
The Journal of experimental medicine 1989;170(6):1887-904.
1989: John W Kappler; E Kushnir; Philippa Marrack
Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype.
The Journal of experimental medicine 1989;169(5):1533-41.
1989: A M Pullen; Philippa Marrack; John W Kappler
Evidence that Mls-2 antigens which delete V beta 3+ T cells are controlled by multiple genes.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3033-7.
1989: R T Kubo; Willi K Born; John W Kappler; Philippa Marrack; M Pigeon
Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(8):2736-42.
1989: J White; A Herman; A M Pullen; R Kubo; John W Kappler; Philippa Marrack
The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice.
Cell 1989;56(1):27-35.
1989: John W Kappler; A Pullen; J Callahan; Y Choi; A Herman; J White; W Potts; E Wakeland; Philippa Marrack
Consequences of self and foreign superantigen interaction with specific V beta elements of the murine TCR alpha beta.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():401-7.
1988: A M Carbone; Philippa Marrack; John W Kappler
Demethylated CD8 gene in CD4+ T cells suggests that CD4+ cells develop from CD8+ precursors.
Science (New York, N.Y.) 1988;242(4882):1174-6.
1988: M McDuffie; N Roehm; John W Kappler; Philippa Marrack
Involvement of major histocompatibility complex products in tolerance induction in the thymus.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(6):1840-7.
1988: T Wade; J Bill; Philippa Marrack; E Palmer; John W Kappler
Molecular basis for the nonexpression of V beta 17 in some strains of mice.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(6):2165-7.
1988: A M Carbone; Philippa Marrack; John W Kappler
Remethylation at sites 5' of the murine Lyt-2 gene in association with shutdown of Lyt-2 expression.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(4):1369-75.
1988: M A Blackman; John W Kappler; Philippa Marrack
T-cell specificity and repertoire.
Immunological reviews 1988;101():5-19.
1987: M McDuffie; N Roehm; W Born; Philippa Marrack; John W Kappler
T cell receptor/MHC interactions in the thymus and the shaping of the T cell repertoire.
Transplantation proceedings 1987;19(6 Suppl 7):111-6.
1987: T H Finkel; M McDuffie; John W Kappler; Philippa Marrack; J C Cambier
Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking.
Nature 1987;330(6144):179-81.
1987: John W Kappler; N Roehm; Philippa Marrack
T cell tolerance by clonal elimination in the thymus.
Cell 1987;49(2):273-80.
1987: John W Kappler; T Wade; J White; E Kushnir; M Blackman; J Bill; N Roehm; Philippa Marrack
A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product.
Cell 1987;49(2):263-71.
1985: N W Roehm; A Carbone; E Kushnir; B A Taylor; R J Riblet; Philippa Marrack; John W Kappler
The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(3):2176-82.
1984: H J Leibson; M Gefter; Albert Zlotnik; Philippa Marrack; John W Kappler
Role of gamma-interferon in antibody-producing responses.
Nature 1984;309(5971):799-801.
1983: Albert Zlotnik; W K Roberts; A Vasil; E Blumenthal; F Larosa; H J Leibson; R O Endres; S D Graham; J White; J Hill; P Henson; J R Klein; M J Bevan; Philippa Marrack; John W Kappler
Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine?
Journal of immunology (Baltimore, Md. : 1950) 1983;131(2):794-800.
1983: N W Roehm; Philippa Marrack; John W Kappler
Helper signals in the plaque-forming cell response to protein-bound haptens.
The Journal of experimental medicine 1983;158(2):317-33.
1983: R O Endres; E Kushnir; John W Kappler; Philippa Marrack; S C Kinsky
A requirement for nonspecific T cell factors in antibody responses to "T cell independent" antigens.
Journal of immunology (Baltimore, Md. : 1950) 1983;130(2):781-4.
1982: N W Roehm; Philippa Marrack; John W Kappler
Antigen-specific, H-2-restricted helper T cell hybridomas.
The Journal of experimental medicine 1982;156(1):191-204.
1982: Philippa Marrack; S D Graham; E Kushnir; H J Leibson; N Roehm; John W Kappler
Nonspecific factors in B cell responses.
Immunological reviews 1982;63():33-49.
1982: R O Endres; E Kushnir; John W Kappler; Philippa Marrack; S C Kinsky
A role for T cell helper factors in antibody responses to "T-independent" antigens.
Lymphokine research 1982;1(4):99-106.
1981: H J Leibson; Philippa Marrack; John W Kappler
B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor.
The Journal of experimental medicine 1981;154(5):1681-93.