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Martien Kapsenberg

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Angelic M G van der Aar; S Marieke Van Ham; Sebastian A J Zaat; Jan D Bos; Leonie de Boer; Thaddeus C George; Hans Janssen; Martien L Kapsenberg; Femke J Muller; Daisy I Picavet; Marcel B M Teunissen; Toni M M van Capel; Esther C de Jong
Langerhans cells favor skin flora tolerance through limited presentation of bacterial antigens and induction of regulatory T cells.
Rosa de Groot; Esther C de Jong; Esther W M Taanman-Kueter; Astrid J van Beelen; Ghaith Bakdash; Martien L Kapsenberg
Viral dsRNA-activated human dendritic cells produce IL-27, which selectively promotes cytotoxicity in naive CD8+ T cells.
Jeroen den Dunnen; Martien L Kapsenberg; Taco W Kuijpers; Femke J M Muller; Lisa T C Vogelpoel; Tomasz Wypych; Sebastian A J Zaat; Leonie de Boer; Esther C de Jong
IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells.

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2013: Angelic M G van der Aar; S Marieke Van Ham; Sebastian A J Zaat; Jan D Bos; Leonie de Boer; Thaddeus C George; Hans Janssen; Martien L Kapsenberg; Femke J Muller; Daisy I Picavet; Marcel B M Teunissen; Toni M M van Capel; Esther C de Jong
Langerhans cells favor skin flora tolerance through limited presentation of bacterial antigens and induction of regulatory T cells.
The Journal of investigative dermatology 2013;133(5):1240-9.
2012: Rosa de Groot; Esther C de Jong; Esther W M Taanman-Kueter; Astrid J van Beelen; Ghaith Bakdash; Martien L Kapsenberg
Viral dsRNA-activated human dendritic cells produce IL-27, which selectively promotes cytotoxicity in naive CD8+ T cells.
Journal of leukocyte biology 2012;92(3):605-10.
2012: Jeroen den Dunnen; Martien L Kapsenberg; Taco W Kuijpers; Femke J M Muller; Lisa T C Vogelpoel; Tomasz Wypych; Sebastian A J Zaat; Leonie de Boer; Esther C de Jong
IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells.
Blood 2012;120(1):112-21.
2012: Inge L Huibregtse; Martien L Kapsenberg; Maikel Peppelenbosch; Maria A Sartori da Silva; Sander J H van Deventer; Sebatian A Zaat; Henri Braat
Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells.
Gastroenterology research and practice 2012;2012():639291.
2011: Jelle de Wit; Tineke Jorritsma; Martien L Kapsenberg; Hanny Klaasse Bos; Femke J M Muller; Yuri Souwer; Astrid J van Beelen; Rosa de Groot; Esther C de Jong; S Marieke Van Ham
CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation.
Blood 2011;118(23):6107-14.
2011: Angelic M G van der Aar; René A W van Lier; Rosa de Groot; Esther C de Jong; Marta Sanchez-Hernandez; Esther W M Taanman; Marcel B M Teunissen; Martien L Kapsenberg
Cutting edge: virus selectively primes human langerhans cells for CD70 expression promoting CD8+ T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(7):3488-92.
2011: Angelic M G van der Aar; Darya S Sibiryak; Ghaith Bakdash; Toni M M van Capel; Hanneke P M van der Kleij; Dirk-Jan E Opstelten; Marcel B M Teunissen; Martien L Kapsenberg; Esther C de Jong
Vitamin D3 targets epidermal and dermal dendritic cells for induction of distinct regulatory T cells.
The Journal of allergy and clinical immunology 2011;127(6):1532-40.e7.
2010: Yuri Souwer; Krisztina Szegedi; Martien L Kapsenberg; Esther C de Jong
IL-17 and IL-22 in atopic allergic disease.
Current opinion in immunology 2010;22(6):821-6.
2009: Martien L Kapsenberg
Gammadelta T cell receptors without a job.
Immunity 2009;31(2):181-3.
2008: M Cristina Lebre; Toni M M van Capel; Jan D Bos; Edward F Knol; Martien L Kapsenberg; Esther C de Jong
Aberrant function of peripheral blood myeloid and plasmacytoid dendritic cells in atopic dermatitis patients.
The Journal of allergy and clinical immunology 2008;122(5):969-976.e5.
2007: Francesca Milano; Agnieszka M Rygiel; Navtej S Buttar; Jacques J G H M Bergman; Carine Sondermeijer; Jantine van Baal; Anja ten Brinke; Martien L Kapsenberg; S Marieke Van Ham; Maikel Peppelenbosch; Kausilia K Krishnadath
An ex vivo readout for evaluation of dendritic cell-induced autologous cytotoxic T lymphocyte responses against esophageal cancer.
Cancer immunology, immunotherapy : CII 2007;56(12):1967-77.
2007: Astrid J van Beelen; Zuzana Zelinkova; Esther W Taanman-Kueter; Femke J Muller; Daan W Hommes; Sebastian A J Zaat; Martien L Kapsenberg; Esther C de Jong
Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells.
Immunity 2007;27(4):660-9.
2007: Astrid J van Beelen; Marcel B M Teunissen; Martien L Kapsenberg; Esther C de Jong
Interleukin-17 in inflammatory skin disorders.
Current opinion in allergy and clinical immunology 2007;7(5):374-81.
2007: Sander W Tas; Margriet J Vervoordeldonk; Najat Hajji; Joost Schuitemaker; Koenraad F van der Sluijs; Michael May; Sankar Ghosh; Martien L Kapsenberg; Paul P Tak; Esther C de Jong
Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation.
Blood 2007;110(5):1540-9.
2007: Francesca Milano; Jantine van Baal; Agnieszka M Rygiel; Jacques J G H M Bergman; Sander J H van Deventer; Martien L Kapsenberg; Maikel Peppelenbosch; Kausilia K Krishnadath
An improved protocol for generation of immuno-potent dendritic cells through direct electroporation of CD14+ monocytes.
Journal of immunological methods 2007;321(1-2):94-106.
2007: Angelic M G van der Aar; Regien M R Sylva-Steenland; Jan D Bos; Martien L Kapsenberg; Esther C de Jong; Marcel B M Teunissen
Loss of TLR2, TLR4, and TLR5 on Langerhans cells abolishes bacterial recognition.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):1986-90.
2007: M Cristina Lebre; Angelic M G van der Aar; Lisa G M van Baarsen; Toni M M van Capel; Joost Schuitemaker; Martien L Kapsenberg; Esther C de Jong
Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9.
The Journal of investigative dermatology 2007;127(2):331-41.
2006: Fedde Groot; Toni M M van Capel; Martien L Kapsenberg; Ben Berkhout; Esther C de Jong
Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition.
Blood 2006;108(6):1957-64.
2006: Martien L Kapsenberg
Tweaking of memory T helper 2 cells by TSLP.
Immunity 2006;24(6):673-5.
2006: Esther C de Jong; Martien L Kapsenberg
Future perspectives of novel immunomodulating substances in immunotherapy.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 2006;(95):207-10; discussion 210.
2005: Anna Skowera; Esther C de Jong; Joost Schuitemaker; Jennifer S Allen; Simon Wessely; Gareth Griffiths; Martien L Kapsenberg; Mark Peakman
Analysis of anthrax and plague biowarfare vaccine interactions with human monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7235-43.
2005: M Cristina Lebre; Timothy J Burwell; Pedro L Vieira; Jose M Lora; Anthony J Coyle; Martien L Kapsenberg; Björn E Clausen; Esther C de Jong
Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation.
Immunology and cell biology 2005;83(5):525-35.
2005: Hermelijn H Smits; Anneke Engering; Desiree Van der Kleij; Esther C de Jong; Kim Schipper; Toni M M van Capel; Bas A J Zaat; Maria Yazdanbakhsh; Eddy A Wierenga; Yvette van Kooyk; Martien L Kapsenberg
Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.
The Journal of allergy and clinical immunology 2005;115(6):1260-7.
2005: Clare L Bennett; Erwin van Rijn; Steffen Jung; Kayo Inaba; Ralph M Steinman; Martien L Kapsenberg; Björn E Clausen
Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity.
The Journal of cell biology 2005;169(4):569-76.
2005: Hermelijn H Smits; Esther C de Jong; Eddy A Wierenga; Martien L Kapsenberg
Different faces of regulatory DCs in homeostasis and immunity.
Trends in immunology 2005;26(3):123-9.
2005: Esther C de Jong; Hermelijn H Smits; Martien L Kapsenberg
Dendritic cell-mediated T cell polarization.
Springer seminars in immunopathology 2005;26(3):289-307.
2004: Mathijs P Bergman; Anneke Engering; Hermelijn H Smits; Sandra J van Vliet; Ad van Bodegraven; Hans-Peter Wirth; Martien L Kapsenberg; Christina M.J.E, Vandenbroucke-Grauls; Yvette van Kooyk; Ben J Appelmelk
Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN.
The Journal of experimental medicine 2004;200(8):979-90.
2004: Robbie B Mailliard; Anna Wankowicz-Kalinska; Quan Cai; Amy Wesa; Catharien M Hilkens; Martien L Kapsenberg; John M Kirkwood; Walter J Storkus; Pawel Kalinski
alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity.
Cancer research 2004;64(17):5934-7.
2004: Lianne Wassink; Pedro L Vieira; Hermelijn H Smits; Gillian A Kingsbury; Anthony J Coyle; Martien L Kapsenberg; Eddy A Wierenga
ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1779-86.
2004: Joost L M Vissers; Betty C A M van Esch; Gerard A Hofman; Martien L Kapsenberg; Frank R Weller; Antoon J M Van Oosterhout
Allergen immunotherapy induces a suppressive memory response mediated by IL-10 in a mouse asthma model.
The Journal of allergy and clinical immunology 2004;113(6):1204-10.
2004: Hermelijn H Smits; Astrid J van Beelen; Christina Hessle; Robert Westland; Esther de Jong; Eelco Soeteman; Agnes E Wold; Eddy A Wierenga; Martien L Kapsenberg
Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development.
European journal of immunology 2004;34(5):1371-80.
2004: Pedro L Vieira; Lianne Wassink; L Mary Smith; Samuel Nam; Gillian A Kingsbury; Jose-Carlos Gutierrez-Ramos; Anthony J Coyle; Martien L Kapsenberg; Eddy A Wierenga
ICOS-mediated signaling regulates cytokine production by human T cells and provides a unique signal to selectively control the clonal expansion of Th2 helper cells.
European journal of immunology 2004;34(5):1282-90.
2004: Henri Braat; Esther C de Jong; Jan M H Van Den Brande; Martien L Kapsenberg; Maikel Peppelenbosch; Eric A F van Tol; Sander J H van Deventer
Dichotomy between Lactobacillus rhamnosus and Klebsiella pneumoniae on dendritic cell phenotype and function.
Journal of molecular medicine (Berlin, Germany) 2004;82(3):197-205.
2003: Martien L Kapsenberg
Dendritic-cell control of pathogen-driven T-cell polarization.
Nature reviews. Immunology 2003;3(12):984-93.
2003: Pawel Kalinski; M Cristina Lebre; D Kramer; Esther C de Jong; J W P M Van Schijndel; Martien L Kapsenberg
Analysis of the CD4+ T cell responses to house dust mite allergoid.
Allergy 2003;58(7):648-56.
2003: Heleen C Heystek; Bianca den Drijver; Martien L Kapsenberg; René A W van Lier; Esther C de Jong
Type I IFNs differentially modulate IL-12p70 production by human dendritic cells depending on the maturation status of the cells and counteract IFN-gamma-mediated signaling.
Clinical immunology (Orlando, Fla.) 2003;107(3):170-7.
2003: M Cristina Lebre; Jeanine C Antons; Pawel Kalinski; Joost Schuitemaker; Toni M M van Capel; Martien L Kapsenberg; Esther C de Jong
Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type-1 polarized phenotype in dendritic cells: role of keratinocyte-derived tumor necrosis factor alpha, type I interferons, and interleukin-18.
The Journal of investigative dermatology 2003;120(6):990-7.
2003: Pedro L Vieira; Heleen C Heystek; Jan Wormmeester; Eddy A Wierenga; Martien L Kapsenberg
Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(9):4483-8.
2003: Pawel Kalinski; Pedro Vieira; Joost Schuitemaker; Quan Cai; Martien L Kapsenberg
Generation of human type 1- and type 2-polarized dendritic cells from peripheral blood.
Methods in molecular biology (Clifton, N.J.) 2003;215():427-36.
2002: Desiree Van der Kleij; Eicke Latz; Jos F H M Brouwers; Yvonne C M Kruize; Marion Schmitz; Evelyn A Kurt-Jones; Terje Espevik; Esther C de Jong; Martien L Kapsenberg; Douglas T Golenbock; Aloysius Tielens; Maria Yazdanbakhsh
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
The Journal of biological chemistry 2002;277(50):48122-9.
2002: Rogier W Sanders; Esther C de Jong; Chris E Baldwin; Joost Schuitemaker; Martien L Kapsenberg; Ben Berkhout
Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells.
Journal of virology 2002;76(15):7812-21.
2002: Robbie B Mailliard; Shinichi Egawa; Quan Cai; Anna Kalinska; Svetlana N Bykovskaya; Michael T Lotze; Martien L Kapsenberg; Walter J Storkus; Pawel Kalinski
Complementary dendritic cell-activating function of CD8+ and CD4+ T cells: helper role of CD8+ T cells in the development of T helper type 1 responses.
The Journal of experimental medicine 2002;195(4):473-83.
2002: Desiree Van der Kleij; Alexandra Van Remoortere; Joost Schuitemaker; Martien L Kapsenberg; André M Deelder; Aloysius Tielens; Cornelis H Hokke; Maria Yazdanbakhsh
Triggering of innate immune responses by schistosome egg glycolipids and their carbohydrate epitope GalNAc beta 1-4(Fuc alpha 1-2Fuc alpha 1-3)GlcNAc.
The Journal of infectious diseases 2002;185(4):531-9.
2002: Hermelijn H Smits; Esther C de Jong; Joost Schuitemaker; Teunis B H Geijtenbeek; Yvette van Kooyk; Martien L Kapsenberg; Eddy A Wierenga
Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1710-6.
2002: Esther C de Jong; Pedro L Vieira; Pawel Kalinski; Joost Schuitemaker; Yuetsu Tanaka; Eddy A Wierenga; Maria Yazdanbakhsh; Martien L Kapsenberg
Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse th cell-polarizing signals.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1704-9.
2001: Hermelijn H Smits; Catharien M U Hilkens; Pawel Kalinski; Martien L Kapsenberg; Eddy A Wierenga
How to deal with polarized Th2 cells: exploring the Achilles' heel.
International archives of allergy and immunology 2001;126(2):102-10.
2001: P Kaliński; Pedro L Vieira; Joost Schuitemaker; Esther C de Jong; Martien L Kapsenberg
Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer.
Blood 2001;97(11):3466-9.
2001: Hermelijn H Smits; J G I van Rietschoten; Catharien M U Hilkens; R Sayilir; F Stiekema; Martien L Kapsenberg; Eddy A Wierenga
IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression.
European journal of immunology 2001;31(4):1055-65.
2000: Martien L Kapsenberg; Catharien M U Hilkens; Tineke C T M van der Pouw Kraan; Eddy A Wierenga; Pawel Kalinski
Atopic allergy: a failure of antigen-presenting cells to properly polarize helper T cells?
American journal of respiratory and critical care medicine 2000;162(3 Pt 2):S76-80.
2000: P Kaliński; Hermelijn H Smits; Joost Schuitemaker; Pedro L Vieira; Martin van Eijk; Esther C de Jong; Eddy A Wierenga; Martien L Kapsenberg
IL-4 is a mediator of IL-12p70 induction by human Th2 cells: reversal of polarized Th2 phenotype by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):1877-81.
2000: Pedro L Vieira; Esther C de Jong; Eddy A Wierenga; Martien L Kapsenberg; P Kaliński
Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4507-12.
1999: P Kaliński; Catharien M U Hilkens; Eddy A Wierenga; Martien L Kapsenberg
T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal.
Immunology today 1999;20(12):561-7.
1999: Esther C de Jong; P L Vieira; Pawel Kalinski; Martien L Kapsenberg
Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3.
Journal of leukocyte biology 1999;66(2):201-4.
1999: Martien L Kapsenberg; Pawel Kalinski
The concept of type 1 and type 2 antigen-presenting cells.
Immunology letters 1999;69(1):5-6.
1999: Martien L Kapsenberg; Catharien M U Hilkens; Eddy A Wierenga; Pawel Kalinski
The paradigm of type 1 and type 2 antigen-presenting cells. Implications for atopic allergy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29 Suppl 2():33-6.
1999: P Kaliński; Joost Schuitemaker; Catharien M U Hilkens; Eddy A Wierenga; Martien L Kapsenberg
Final maturation of dendritic cells is associated with impaired responsiveness to IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3231-6.
1999: Eddy A Wierenga; Monika Walchner; G Kick; Martien L Kapsenberg; E H Weiss; Gerald Messer
Evidence for suppressed activity of the transcription factor NFAT1 at its proximal binding element P0 in the IL-4 promoter associated with enhanced IL-4 gene transcription in T cells of atopic patients.
International immunology 1999;11(2):297-306.
1999: A Wassenaar; T Verschoor; femia kievits; M T Den Hartog; Martien L Kapsenberg; V Everts; A Snijders
CD40 engagement modulates the production of matrix metalloproteinases by gingival fibroblasts.
Clinical and experimental immunology 1999;115(1):161-7.
1998: Martien L Kapsenberg; Catharien M U Hilkens; Eddy A Wierenga; Pawel Kalinski
The role of antigen-presenting cells in the regulation of allergen-specific T cell responses.
Current opinion in immunology 1998;10(6):607-13.
1998: Pedro L Vieira; P Kaliński; Eddy A Wierenga; Martien L Kapsenberg; Esther C de Jong
Glucocorticoids inhibit bioactive IL-12p70 production by in vitro-generated human dendritic cells without affecting their T cell stimulatory potential.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5245-51.
1998: A Snijders; Pawel Kalinski; Catharien M U Hilkens; Martien L Kapsenberg
High-level IL-12 production by human dendritic cells requires two signals.
International immunology 1998;10(11):1593-8.
1998: Antoon J M Van Oosterhout; Betty C A M van Esch; Gerard A Hofman; CL Hofstra; Ingrid van Ark; Frans P Nijkamp; Martien L Kapsenberg; HF Savelkoul; F R Weller
Allergen immunotherapy inhibits airway eosinophilia and hyperresponsiveness associated with decreased IL-4 production by lymphocytes in a murine model of allergic asthma.
American journal of respiratory cell and molecular biology 1998;19(4):622-8.
1998: P Kaliński; Joost Schuitemaker; Catharien M U Hilkens; Martien L Kapsenberg
Prostaglandin E2 induces the final maturation of IL-12-deficient CD1a+CD83+ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(6):2804-9.
1998: R J J Van Neerven; Marjan van de Pol; jaring s. van der zee; F E Stiekema; M De Boer; Martien L Kapsenberg
Requirement of CD28-CD86 costimulation for allergen-specific T cell proliferation and cytokine expression.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(7):808-16.
1998: A Snijders; Tineke C T M van der Pouw Kraan; M Engel; Jan Wormmeester; P Widjaja; I M Zonneveld; J D Bos; Martien L Kapsenberg
Enhanced prostaglandin E2 production by monocytes in atopic dermatitis (AD) is not accompanied by enhanced production of IL-6, IL-10 or IL-12.
Clinical and experimental immunology 1998;111(3):472-6.
1997: A Wassenaar; A Snijders; L Abraham-Inpijn; Martien L Kapsenberg; femia kievits
Antigen-presenting properties of gingival fibroblasts in chronic adult periodontitis.
Clinical and experimental immunology 1997;110(2):277-84.
1997: Catharien M U Hilkens; Pawel Kalinski; Martin de Boer; Martien L Kapsenberg
Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype.
Blood 1997;90(5):1920-6.
1997: P Kaliński; Catharien M U Hilkens; A Snijders; FG Snijdewint; Martien L Kapsenberg
IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):28-35.
1997: Tineke C T M van der Pouw Kraan; LC Boeije; Els R de Groot; Steven O Stapel; A Snijders; Martien L Kapsenberg; jaring s. van der zee; Lucien A Aarden
Reduced production of IL-12 and IL-12-dependent IFN-gamma release in patients with allergic asthma.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5560-5.
1997: M Barna; Jan D Bos; Martien L Kapsenberg; FG Snijdewint
Effect of calcitriol on the production of T-cell-derived cytokines in psoriasis.
The British journal of dermatology 1997;136(4):536-41.
1997: P Kaliński; Catharien M U Hilkens; A Snijders; FG Snijdewint; Martien L Kapsenberg
Dendritic cells, obtained from peripheral blood precursors in the presence of PGE2, promote Th2 responses.
Advances in experimental medicine and biology 1997;417():363-7.
1996: Catharien M U Hilkens; G Messer; kiki tesselaar; A G van Rietschoten; Martien L Kapsenberg; Eddy A Wierenga
Lack of IL-12 signaling in human allergen-specific Th2 cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4316-21.
1996: R J J Van Neerven; C Ebner; H Yssel; Martien L Kapsenberg; J R Lamb
T-cell responses to allergens: epitope-specificity and clinical relevance.
Immunology today 1996;17(11):526-32.
1996: Catharien M U Hilkens; A Snijders; H Vermeulen; P van der Meide; Eddy A Wierenga; Martien L Kapsenberg
Accessory cell-derived interleukin-12 and prostaglandin E2 determine the level of interferon-gamma produced by activated human CD4+ T cells.
Annals of the New York Academy of Sciences 1996;795():349-50.
1996: I B Kremer; Catharien M U Hilkens; Regien M R Sylva-Steenland; Cornelis W Koomen; Martien L Kapsenberg; Jan D Bos; Marcel B M Teunissen
Reduced IL-12 production by monocytes upon ultraviolet-B irradiation selectively limits activation of T helper-1 cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(5):1913-8.
1996: Catharien M U Hilkens; A Snijders; F G Snijdewint; Eddy A Wierenga; Martien L Kapsenberg
Modulation of T-cell cytokine secretion by accessory cell-derived products.
The European respiratory journal. Supplement 1996;22():90s-94s.
1996: Martien L Kapsenberg
Chemicals and proteins as allergens and adjuvants.
Toxicology letters 1996;86(2-3):79-83.
1996: F H Pistoor; A Rambukkana; M Kroezen; J P Lepoittevin; Jan D Bos; Martien L Kapsenberg; Pranab K Das
Novel predictive assay for contact allergens using human skin explant cultures.
The American journal of pathology 1996;149(1):337-43.
1996: Martien L Kapsenberg; Catharien M U Hilkens; Henk M Jansen; Jan D Bos; A Snijders; Eddy A Wierenga
Production and modulation of T-cell cytokines in atopic allergy.
International archives of allergy and immunology 1996;110(2):107-13.
1996: Catharien M U Hilkens; A Snijders; H Vermeulen; P H van der Meide; Eddy A Wierenga; Martien L Kapsenberg
Accessory cell-derived IL-12 and prostaglandin E2 determine the IFN-gamma level of activated human CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(5):1722-27.
1996: Dörte Hamann; Catharien M U Hilkens; Jane Grogan; SM Lens; Martien L Kapsenberg; Maria Yazdanbakhsh; René A W van Lier
CD30 expression does not discriminate between human Th1- and Th2-type T cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(4):1387-91.
1996: A Rambukkana; F H Pistoor; Jan D Bos; Martien L Kapsenberg; Pranab K Das
Effects of contact allergens on human Langerhans cells in skin organ culture: migration, modulation of cell surface molecules, and early expression of interleukin-1 beta protein.
Laboratory investigation; a journal of technical methods and pathology 1996;74(2):422-36.
1996: A Snijders; Catharien M U Hilkens; Tineke C T M van der Pouw Kraan; M Engel; Lucien A Aarden; Martien L Kapsenberg
Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1207-12.
1996: Martien L Kapsenberg; Catharien M U Hilkens; Tineke C T M van der Pouw Kraan; Eddy A Wierenga; A Snijders
The role of accessory cell products in the regulation of T cell cytokine production.
Advances in experimental medicine and biology 1996;409():305-8.
1995: A Rambukkana; Jan D Bos; D Irik; W J Menko; Martien L Kapsenberg; Pranab K Das
In situ behavior of human Langerhans cells in skin organ culture.
Laboratory investigation; a journal of technical methods and pathology 1995;73(4):521-31.
1995: F H Pistoor; Martien L Kapsenberg; Jan D Bos; Marcus M H M Meinardi; M E von Blomberg; R J Scheper
Cross-reactivity of human nickel-reactive T-lymphocyte clones with copper and palladium.
The Journal of investigative dermatology 1995;105(1):92-5.
1995: P Kaliński; Catharien M U Hilkens; Eddy A Wierenga; Tineke C T M van der Pouw Kraan; René A W van Lier; Jan D Bos; Martien L Kapsenberg; F G Snijdewint
Functional maturation of human naive T helper cells in the absence of accessory cells. Generation of IL-4-producing T helper cells does not require exogenous IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3753-60.
1995: F G Snijdewint; Martien L Kapsenberg; P J Wauben-Penris; Jan D Bos
Corticosteroids class-dependently inhibit in vitro Th1- and Th2-type cytokine production.
Immunopharmacology 1995;29(2):93-101.
1995: F L van der Heijden; R J J Van Neerven; Martien L Kapsenberg
Relationship between facilitated allergen presentation and the presence of allergen-specific IgE in serum of atopic patients.
Clinical and experimental immunology 1995;99(2):289-93.
1995: Catharien M U Hilkens; H Vermeulen; R J J Van Neerven; F G Snijdewint; Eddy A Wierenga; Martien L Kapsenberg
Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E2 critically depends on interleukin-2.
European journal of immunology 1995;25(1):59-63.
1994: R J J Van Neerven; M M van de Pol; Eddy A Wierenga; Rob C Aalberse; Henk M Jansen; Martien L Kapsenberg
Peptide specificity and HLA restriction do not dictate lymphokine production by allergen-specific T-lymphocyte clones.
Immunology 1994;82(3):351-6.
1994: R J J Van Neerven; M M van de Pol; F J van Milligen; Henk M Jansen; Rob C Aalberse; Martien L Kapsenberg
Characterization of cat dander-specific T lymphocytes from atopic patients.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(8):4203-10.
1994: M Barna; F G Snijdewint; F L van der Heijden; Jan D Bos; Martien L Kapsenberg
Characterization of lesional psoriatic skin T lymphocyte clones.
Acta dermato-venereologica. Supplementum 1994;186():9-11.
1993: Eddy A Wierenga; B Backx; M Snoek; Leo Koenderman; Martien L Kapsenberg
Relative contributions of human types 1 and 2 T-helper cell-derived eosinophilotrophic cytokines to development of eosinophilia.
Blood 1993;82(5):1471-9.
1993: R Joost van Neerven; W van t'Hof; J H Ringrose; Henk M Jansen; Rob C Aalberse; Eddy A Wierenga; Martien L Kapsenberg
T cell epitopes of house dust mite major allergen Der p II.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):2326-35.
1993: F G Snijdewint; P Kaliński; Eddy A Wierenga; Jan D Bos; Martien L Kapsenberg
Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(12):5321-9.
1993: F L van der Heijden; R J Joost van Neerven; M van Katwijk; Jan D Bos; Martien L Kapsenberg
Serum-IgE-facilitated allergen presentation in atopic disease.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(8 Pt 1):3643-50.
1993: Jan D Bos; Martien L Kapsenberg
The skin immune system: progress in cutaneous biology.
Immunology today 1993;14(2):75-8.
1992: Martien L Kapsenberg; Henk M Jansen; Jan D Bos; Eddy A Wierenga
Role of type 1 and type 2 T helper cells in allergic diseases.
Current opinion in immunology 1992;4(6):788-93.
1992: Jan D Bos; Eddy A Wierenga; J H Sillevis Smitt; F L van der Heijden; Martien L Kapsenberg
Immune dysregulation in atopic eczema.
Archives of dermatology 1992;128(11):1509-12.
1992: Marcel B M Teunissen; F H Pistoor; H A Rongen; Martien L Kapsenberg; Jan D Bos
A comparison of the inhibitory effects of immunosuppressive agents cyclosporine, tetranactin, and didemnin B on human T cell responses in vitro.
Transplantation 1992;53(4):875-81.
1992: Martien L Kapsenberg; Jan D Bos; Eddy A Wierenga
T cells in allergic responses to haptens and proteins.
Springer seminars in immunopathology 1992;13(3-4):303-14.
1992: Martien L Kapsenberg; Eddy A Wierenga; F E Stiekema; A M Tiggelman; Jan D Bos
Th1 lymphokine production profiles of nickel-specific CD4+T-lymphocyte clones from nickel contact allergic and non-allergic individuals.
The Journal of investigative dermatology 1992;98(1):59-63.
1991: Martien L Kapsenberg; Eddy A Wierenga; Jan D Bos; H M Jansen
Functional subsets of allergen-reactive human CD4+ T cells.
Immunology today 1991;12(11):392-5.
1991: Eddy A Wierenga; M Snoek; Henk M Jansen; Jan D Bos; René A W van Lier; Martien L Kapsenberg
Human atopen-specific types 1 and 2 T helper cell clones.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(9):2942-9.
1991: Marcel B M Teunissen; M H De Jager; Martien L Kapsenberg; Jan D Bos
Inhibitory effect of cyclosporin A on antigen and alloantigen presenting capacity of human epidermal Langerhans cells.
The British journal of dermatology 1991;125(4):309-16.
1991: F L van der Heijden; Eddy A Wierenga; Jan D Bos; Martien L Kapsenberg
High frequency of IL-4-producing CD4+ allergen-specific T lymphocytes in atopic dermatitis lesional skin.
The Journal of investigative dermatology 1991;97(3):389-94.
1991: Martien L Kapsenberg; Eddy A Wierenga; J D Bos; Henk M Jansen
Aberrant T cell regulation of IgE production in atopy.
The European respiratory journal. Supplement 1991;13():27s-30s.
1990: Eddy A Wierenga; M Snoek; Jan D Bos; Henk M Jansen; Martien L Kapsenberg
Comparison of diversity and function of house dust mite-specific T lymphocyte clones from atopic and non-atopic donors.
European journal of immunology 1990;20(7):1519-26.
1990: Eddy A Wierenga; M Snoek; Cornelis de Groot; I Chrétien; Jan D Bos; Henk M Jansen; Martien L Kapsenberg
Evidence for compartmentalization of functional subsets of CD2+ T lymphocytes in atopic patients.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4651-6.
1990: Marcel B M Teunissen; J Wormmeester; S R Krieg; P J Peters; I M Vogels; Martien L Kapsenberg; Jan D Bos
Human epidermal Langerhans cells undergo profound morphologic and phenotypical changes during in vitro culture.
The Journal of investigative dermatology 1990;94(2):166-73.
1990: Jan D Bos; Marcel B M Teunissen; I Cairo; S R Krieg; Martien L Kapsenberg; Pranab K Das; Jannie Borst
T-cell receptor gamma delta bearing cells in normal human skin.
The Journal of investigative dermatology 1990;94(1):37-42.
1989: Martien L Kapsenberg; F E Stiekema; A Kallan; Jan D Bos; R C Roozemond
The restrictive role of sialic acid in antigen presentation to a subset of human peripheral CD4+ T lymphocytes that requires antigen-presenting dendritic cells.
European journal of immunology 1989;19(10):1829-34.
1989: Jan D Bos; Marcel B M Teunissen; Martien L Kapsenberg
Immunology of contact dermatitis.
Acta dermato-venereologica. Supplementum 1989;151():84-7; discussion 106-10.
1989: Jan D Bos; C Hagenaars; Pranab K Das; S R Krieg; W J Voorn; Martien L Kapsenberg
Predominance of "memory" T cells (CD4+, CDw29+) over "naive" T cells (CD4+, CD45R+) in both normal and diseased human skin.
Archives of dermatological research 1989;281(1):24-30.
1988: Marcel B M Teunissen; J Wormmeester; Martien L Kapsenberg; Jan D Bos
Enrichment of unlabeled human Langerhans cells from epidermal cell suspensions by discontinuous density gradient centrifugation.
The Journal of investigative dermatology 1988;91(4):358-62.
1988: Martien L Kapsenberg; T Van der Pouw-Kraan; F E Stiekema; A Schootemeijer; Jan D Bos
Direct and indirect nickel-specific stimulation of T lymphocytes from patients with allergic contact dermatitis to nickel.
European journal of immunology 1988;18(7):977-82.
1987: Jan D Bos; I Zonneveld; P K Das; S R Krieg; C M van der Loos; Martien L Kapsenberg
The skin immune system (SIS): distribution and immunophenotype of lymphocyte subpopulations in normal human skin.
The Journal of investigative dermatology 1987;88(5):569-73.
1987: P Res; Martien L Kapsenberg; Jan D Bos; F Stiekema
The crucial role of human dendritic antigen-presenting cell subsets in nickel-specific T-cell proliferation.
The Journal of investigative dermatology 1987;88(5):550-4.
1987: F E Stiekema; Martien L Kapsenberg
Accessory cell requirements in mitogen-induced rabbit T lymphocyte proliferation in an improved tissue culture system.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1987;23(4):253-6.
1986: Martien L Kapsenberg; Marcel B M Teunissen; F E Stiekema; H G Keizer
Antigen-presenting cell function of dendritic cells and macrophages in proliferative T cell responses to soluble and particulate antigens.
European journal of immunology 1986;16(4):345-50.
1985: Martien L Kapsenberg; F Stiekema; W Leene
Differential requirements for rabbit dendritic cells and macrophages in T lymphocyte proliferation induced by various mitogens.
Immunology 1985;55(2):301-10.
1985: Marcel B M Teunissen; Martien L Kapsenberg; F E Stiekema; H G Keizer
Dendritic cells as accessory cells in antigen-specific murine T lymphocyte proliferation in vitro.
Journal of immunological methods 1985;77(1):131-8.
1985: Martien L Kapsenberg; F E Stiekema; Marcel B M Teunissen
Dendritic cells and macrophages as antigen presenting cells in ovalbumin-induced T lymphocyte proliferation in vitro.
Advances in experimental medicine and biology 1985;186():389-94.
1985: Cornelis de Groot; R van Schie; J Wormmeester; Martien L Kapsenberg
In vitro growth and differentiation of rat B cell subpopulations.
Advances in experimental medicine and biology 1985;186():57-64.
1984: Martien L Kapsenberg; Eric van Agtmaal; J Wormmeester; F Stiekema; Paul Roholl
Macrophage support and suppression in rabbit T cell mitogenesis.
Journal of immunological methods 1984;72(1):133-43.
1983: Martien L Kapsenberg; Cornelis de Groot; T Hogenes; W Leene
A simple method for the direct visualization of cell surface-associated lectins and antibodies in freeze fracture electron microscopy.
Ultramicroscopy 1983;12(3):253-60.
1982: Cornelis de Groot; Martien L Kapsenberg; W Leene
Observations on transmembrane structures of surface immunoglobulin in the plasma membrane of B lymphocytes.
Biochimica et biophysica acta 1982;689(2):275-82.
1981: Paul Roholl; W Leene; Martien L Kapsenberg; J G Vos
The use of tannic acid fixation for the electron microscope visualization of fluorochrome-labelled antibodies attached to cell surface antigens.
Journal of immunological methods 1981;42(3):285-9.