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Shitij Kapur

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TOP 3
Delia Bishara; Shitij Kapur; Olubanke Olofinjana; Anna Sparshatt; David Taylor; Maxine X Patel
Olanzapine: a systematic review and meta-regression of the relationships between dose, plasma concentration, receptor occupancy, and response.
Euitae Kim; Ji Who Kim; Jae Sung Lee; Sang-Goo Shin; Federico E Turkheimer; Oliver D Howes; In-Jin Jang; Jae Min Jeong; Shitij Kapur; Bo-Hyung Kim; Jun Soo Kwon
The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory : A dual [(11)C]raclopride and [(18) F]FDG imaging study with aripiprazole.
Rowena Handley; Atholl Johnston; Shitij Kapur; Tiago Reis Marques; Philip McGuire; Mitul A Mehta; Ruth L O'Gorman; Carmine M Pariante; A A T Simone Reinders; Heather Taylor; Steve Williams; Fernando O Zelaya; David C Alsop; Paola Dazzan
Acute effects of single-dose aripiprazole and haloperidol on resting cerebral blood flow (rCBF) in the human brain.

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All Publications

2013: Delia Bishara; Shitij Kapur; Olubanke Olofinjana; Anna Sparshatt; David Taylor; Maxine X Patel
Olanzapine: a systematic review and meta-regression of the relationships between dose, plasma concentration, receptor occupancy, and response.
Journal of clinical psychopharmacology 2013;33(3):329-35.
2013: Euitae Kim; Ji Who Kim; Jae Sung Lee; Sang-Goo Shin; Federico E Turkheimer; Oliver D Howes; In-Jin Jang; Jae Min Jeong; Shitij Kapur; Bo-Hyung Kim; Jun Soo Kwon
The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory : A dual [(11)C]raclopride and [(18) F]FDG imaging study with aripiprazole.
Psychopharmacology 2013;227(2):221-9.
2013: Rowena Handley; Atholl Johnston; Shitij Kapur; Tiago Reis Marques; Philip McGuire; Mitul A Mehta; Ruth L O'Gorman; Carmine M Pariante; A A T Simone Reinders; Heather Taylor; Steve Williams; Fernando O Zelaya; David C Alsop; Paola Dazzan
Acute effects of single-dose aripiprazole and haloperidol on resting cerebral blood flow (rCBF) in the human brain.
Human brain mapping 2013;34(2):272-82.
2013: John Ainsworth; Emma Barkus; Christine Barrowclough; Iain Buchan; Graham Dunn; Richard S Hopkins; Shitij Kapur; Matthew Machin; Jasper E Palmier-Claus; Anne Rogers; Til Wykes; Shôn Lewis
A Comparison of two delivery modalities of a mobile phone-based assessment for serious mental illness: native smartphone application vs text-messaging only implementations.
Journal of medical Internet research 2013;15(4):e60.
2013: Jasper E Palmier-Claus; Anne Rogers; Til Wykes; Matt Machin; John Ainsworth; Emma Barkus; Christine Barrowclough; Shitij Kapur; Louise Laverty; Shôn W Lewis
Integrating mobile-phone based assessment for psychosis into people's everyday lives and clinical care: a qualitative study.
BMC psychiatry 2013;13():34.
2013: Amir Englund; Amanda Feilding; Dominic Hague; David Holt; Fergus Kane; Paul D Morrison; Robin M Murray; Judith Nottage; Avi Reichenberg; James M Stone; Lucy Walker; Stefania Bonaccorso; Rudolf Brenneisen; Shitij Kapur
Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment.
Journal of psychopharmacology (Oxford, England) 2013;27(1):19-27.
2012: Oliver Howes; Shitij Kapur; Philip McGuire; Siobhan Gee; Francis Vergunst; David Taylor
Adherence to treatment guidelines in clinical practice: study of antipsychotic treatment prior to clozapine initiation.
The British journal of psychiatry : the journal of mental science 2012;201(6):481-5.
2012: Mette Odegaard Nielsen; Egill Rostrup; Sanne Wulff; Nikolaj Bak; Brian Villumsen Broberg; Shitij Kapur; Henrik Lublin; Birte Y Glenthoj
Improvement of brain reward abnormalities by antipsychotic monotherapy in schizophrenia.
Archives of general psychiatry 2012;69(12):1195-204.
2012: Arsime Demjaha; Shitij Kapur; Philip K McGuire; Robin M Murray; Oliver Howes
Dopamine synthesis capacity in patients with treatment-resistant schizophrenia.
The American journal of psychiatry 2012;169(11):1203-10.
2012: Nicholas J Bray; Shitij Kapur; Jack Price
Investigating schizophrenia in a "dish": possibilities, potential and limitations.
World psychiatry : official journal of the World Psychiatric Association (WPA) 2012;11(3):153-5.
2012: Oliver Howes; Joseph Kambeitz; Euitae Kim; Mark Slifstein; Daniel Stahl; Anissa Abi-Dargham; Shitij Kapur
The nature of dopamine dysfunction in schizophrenia and what this means for treatment.
Archives of general psychiatry 2012;69(8):776-86.
2012: Sridhar Natesan; Shitij Kapur
Antipsychotic therapy over half a century: a tale of discovery from chlorpromazine to aripiprazole.
The National medical journal of India 2012;25(4):193-5.
2012: Mette Ødegaard Nielsen; Egill Rostrup; Sanne Wulff; Nikolaj Bak; Shitij Kapur; Henrik Lublin; Birte Y Glenthøj
Alterations of the brain reward system in antipsychotic naïve schizophrenia patients.
Biological psychiatry 2012;71(10):898-905.
2012: Anthony C Vernon; Steven C R Williams; Jonathan D Cooper; Bill Crum; Michel Modo; Sridhar Natesan; Shitij Kapur
Contrasting effects of haloperidol and lithium on rodent brain structure: a magnetic resonance imaging study with postmortem confirmation.
Biological psychiatry 2012;71(10):855-63.
2012: Jonathan Rabinowitz; Stephen Levine; Carmen Galani Berardo; Dragana Bugarski-Kirola; George Garibaldi; Shitij Kapur
Negative symptoms have greater impact on functioning than positive symptoms in schizophrenia: analysis of CATIE data.
Schizophrenia research 2012;137(1-3):147-50.
2012: J Mourao-Miranda; Robin M Murray; A A T S Reinders; V Rocha-Rego; J Rondina; gillian doody; Paul Fearon; Peter B Jones; Shitij Kapur; Julia M Lappin; Craig Morgan; Kevin D Morgan; Paola Dazzan
Individualized prediction of illness course at the first psychotic episode: a support vector machine MRI study.
Psychological medicine 2012;42(5):1037-47.
2012: Euitae Kim; Jae Sung Lee; Sang-Goo Shin; Federico E Turkheimer; Oliver D Howes; In-Jin Jang; Jae Min Jeong; Shitij Kapur; Bo-Hyung Kim; Jun Soo Kwon
Predicting brain occupancy from plasma levels using PET: superiority of combining pharmacokinetics with pharmacodynamics while modeling the relationship.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(4):759-68.
2012: Suzanne H So; Shitij Kapur; Elizabeth Kuipers; Paul Bebbington; Graham Dunn; David Fowler; Daniel Freeman; Philippa A Garety
Jumping to conclusions, a lack of belief flexibility and delusional conviction in psychosis: a longitudinal investigation of the structure, frequency, and relatedness of reasoning biases.
Journal of abnormal psychology 2012;121(1):129-39.
2012: Nathalie Ginovart; Shitij Kapur
Role of dopamine D(2) receptors for antipsychotic activity.
Handbook of experimental pharmacology 2012;(212):27-52.
2012: Katherine E Tansey; Jens R Wendland; Katherine J Aitchison; Guido Bondolfi; Ian Craig; Enrico Domenici; David Evans; Anne Farmer; Michel Guipponi; Stephanie K Hall; Joanna Hauser; Neven Henigsberg; Peter Holmans; Xiaolan Hu; Borut Jerman; Shitij Kapur; Cathryn M Lewis; Glyn Lewis; Wolfgang Maier; Alain Malafosse; Peter McGuffin; Ole Mors; Michael O'Donovan; Nader Perroud; Tim J Peters; Anna Placentino; Marcella Rietschel; Daniel Souery; Tine Bryan Stensbøl; Rudolf Uher
Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.
PLoS medicine 2012;9(10):e1001326.
2012: Jasper E Palmier-Claus; Anne Rogers; Emma Salter; Til Wykes; John Ainsworth; Emma Barkus; Cristine Barrowclough; Iain Buchan; Graham Dunn; Shitij Kapur; Matthew Machin; Shôn W Lewis
The feasibility and validity of ambulatory self-report of psychotic symptoms using a smartphone software application.
BMC psychiatry 2012;12():172.
2011: Mahesh Menon; Gary Remington; Taylor W Schmitz; Michele Korostil; David Mamo; Jean Addington; Adam K Anderson; Philip Gerretsen; Ariel Graff-Guerrero; Shitij Kapur
Exploring the neural correlates of delusions of reference.
Biological psychiatry 2011;70(12):1127-33.
2011: Hiroyuki Uchida; Tiffany W Chow; Sylvain Houle; Shitij Kapur; David Mamo; Benoit H Mulsant; Bruce G Pollock; Ariel Graff-Guerrero
Effects of aging on 5-HT(2A) R binding: a HRRT PET study with and without partial volume corrections.
International journal of geriatric psychiatry 2011;26(12):1300-8.
2011: Ofer Agid; Tamara Arenovich; George Foussias; Shitij Kapur; Gautam Sajeev; Robert B Zipursky; Gary Remington
An algorithm-based approach to first-episode schizophrenia: response rates over 3 prospective antipsychotic trials with a retrospective data analysis.
The Journal of clinical psychiatry 2011;72(11):1439-44.
2011: Davide Amato; Shitij Kapur; Sridhar Natesan; Leonid Yavich; Christian P Müller
Dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2011;14(10):1327-39.
2011: Euitae Kim; Su Jin Kim; Yong Gil Kim; Oliver D Howes; In-Jin Jang; Jae Min Jeong; Shitij Kapur; Bo-Hyung Kim; Jae Sung Lee; Jung Shin Park; Sang-Goo Shin; Federico E Turkheimer; Kyung-Sang Yu; Jun Soo Kwon
The use of healthy volunteers instead of patients to inform drug dosing studies: a [¹¹C]raclopride PET study.
Psychopharmacology 2011;217(4):515-23.
2011: Sridhar Natesan; José N Nobrega; Greg E Reckless; Karen B L Barlow; Shitij Kapur
Partial agonists in schizophrenia--why some work and others do not: insights from preclinical animal models.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2011;14(9):1165-78.
2011: Romina Mizrahi; Gary Remington; Pablo Rusjan; Ivonne Suridjan; Alan A Wilson; Ofer Agid; Carol Borlido; Sylvain Houle; Shitij Kapur
Effects of antipsychotics on D3 receptors: a clinical PET study in first episode antipsychotic naive patients with schizophrenia using [11C]-(+)-PHNO.
Schizophrenia research 2011;131(1-3):63-8.
2011: Chisa Tsutsumi; Yuichiro Tsutsumi; Hiroyuki Uchida; Koichiro Watanabe; Yoshie Kimura; Shinichiro Nakajima; Takefumi Suzuki; Hiroyoshi Takeuchi; Yasushi Imasaka; Koichi Ishii; Shitij Kapur
The evolution of antipsychotic switch and polypharmacy in natural practice--a longitudinal perspective.
Schizophrenia research 2011;130(1-3):40-6.
2011: Virginia L Stauffer; Sara Kollack-Walker; Haya Ascher-Svanum; Tamara Ball; Michael Case; Shitij Kapur; Bruce J Kinon
Trajectories of response to treatment with atypical antipsychotic medication in patients with schizophrenia pooled from 6 double-blind, randomized clinical trials.
Schizophrenia research 2011;130(1-3):11-9.
2011: Davide Amato; Sridhar Natesan; Shitij Kapur; Christian P Müller
Haloperidol modulates noradrenergic responses to aversive stimulation depending on treatment duration.
Behavioural brain research 2011;221(1):311-3.
2011: Anna Sparshatt; David Taylor; Maxine X Patel; Shitij Kapur
Relationship between daily dose, plasma concentrations, dopamine receptor occupancy, and clinical response to quetiapine: a review.
The Journal of clinical psychiatry 2011;72(8):1108-23.
2011: Gary Remington; Philip Seeman; Chekkera Shammi; Alan Feingold; Steve Mann; Shitij Kapur
"Extended" antipsychotic dosing in the maintenance treatment of schizophrenia: a double-blind, placebo-controlled trial.
The Journal of clinical psychiatry 2011;72(8):1042-8.
2011: T R Marques; T Arenovich; O Agid; G Sajeev; B Muthén; L Chen; B J Kinon; Shitij Kapur
The different trajectories of antipsychotic response: antipsychotics versus placebo.
Psychological medicine 2011;41(7):1481-8.
2011: Cedric O'Gorman; Shitij Kapur; Sheela Kolluri; John Kane
Early improvement on antipsychotic treatment as a predictor of subsequent response in schizophrenia: analyses from ziprasidone clinical studies.
Human psychopharmacology 2011;26(4-5):282-90.
2011: Anthony C Vernon; Sridhar Natesan; Mike Modo; Shitij Kapur
Effect of chronic antipsychotic treatment on brain structure: a serial magnetic resonance imaging study with ex vivo and postmortem confirmation.
Biological psychiatry 2011;69(10):936-44.
2011: Shitij Kapur
What Kraepelin might say about schizophrenia: just the facts.
Schizophrenia research 2011;128(1-3):1-2.
2011: Paul D Morrison; Judith Nottage; James M Stone; Sagnik Bhattacharyya; Nigel Tunstall; Rudolf Brenneisen; David Holt; Daniel Wilson; Alex Sumich; Philip McGuire; Robin M Murray; Shitij Kapur; Dominic H Ffytche
Disruption of frontal θ coherence by Δ9-tetrahydrocannabinol is associated with positive psychotic symptoms.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(4):827-36.
2011: Shitij Kapur
Looking for a "biological test" to diagnose"schizophrenia": are we chasing red herrings?
World psychiatry : official journal of the World Psychiatric Association (WPA) 2011;10(1):32.
2011: Andreea Oliviana Diaconescu; Jimmy Jensen; Hongye Wang; Matthäus Willeit; Mahesh Menon; Shitij Kapur; Anthony R McIntosh
Aberrant Effective Connectivity in Schizophrenia Patients during Appetitive Conditioning.
Frontiers in human neuroscience 2011;4():239.
2010: Nicholas J Bray; F Markus Leweke; Shitij Kapur; Andreas Meyer-Lindenberg
The neurobiology of schizophrenia: new leads and avenues for treatment.
Current opinion in neurobiology 2010;20(6):810-5.
2010: Anna Sparshatt; David Taylor; Maxine X Patel; Shitij Kapur
A systematic review of aripiprazole--dose, plasma concentration, receptor occupancy, and response: implications for therapeutic drug monitoring.
The Journal of clinical psychiatry 2010;71(11):1447-56.
2010: Gary Remington; Shitij Kapur
Antipsychotic dosing: how much but also how often?
Schizophrenia bulletin 2010;36(5):900-3.
2010: Suzanne H So; Philippa A Garety; Emmanuelle R Peters; Shitij Kapur
Do antipsychotics improve reasoning biases? A review.
Psychosomatic medicine 2010;72(7):681-93.
2010: Panayiota G Michalopoulou; Vincent Giampietro; Lucy A Morley; Adnan Azim; Shitij Kapur; Lefteris Lykouras; Sukhwinder S Shergill
The effects of reality distortion syndrome on salient stimuli processing in patients with schizophrenia: an fMRI study.
Psychiatry research 2010;183(2):93-8.
2010: Patrick N McCormick; Shitij Kapur; Ariel Graff-Guerrero; Roger Raymond; José N Nobrega; Alan A Wilson
The antipsychotics olanzapine, risperidone, clozapine, and haloperidol are D2-selective ex vivo but not in vitro.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(8):1826-35.
2010: Bruce J Kinon; Lei Chen; Virginia L Stauffer; Jennifer Sniadecki; Haya Ascher-Svanum; Sara Kollack-Walker; Jayanthi Jacob; Shitij Kapur
Early onset of antipsychotic action in schizophrenia: evaluating the possibility of shorter acute efficacy trials.
Journal of clinical psychopharmacology 2010;30(3):286-9.
2010: Bruce J Kinon; Lei Chen; Haya Ascher-Svanum; Virginia L Stauffer; Sara Kollack-Walker; Wei Zhou; Shitij Kapur; John M Kane; Dieter Naber
Challenging the assumption that improvement in functional outcomes is delayed relative to improvement in symptoms in the treatment of schizophrenia.
Schizophrenia research 2010;118(1-3):176-82.
2010: Ariel Graff-Guerrero; Laura Redden; Walid Abi-Saab; David A Katz; Sylvain Houle; Penny Barsoum; Anahita Bhathena; Ramesh Palaparthy; Mario Saltarelli; Shitij Kapur
Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2010;13(3):273-87.
2010: Andreea Oliviana Diaconescu; Mahesh Menon; Jimmy Jensen; Shitij Kapur; Anthony R McIntosh
Dopamine-induced changes in neural network patterns supporting aversive conditioning.
Brain research 2010;1313():143-61.
2010: Sagnik Bhattacharyya; Paul D Morrison; Paolo Fusar-Poli; Rocio Martin-Santos; Stefan J Borgwardt; Toby Winton-Brown; Chiara Nosarti; Colin M O' Carroll; Marc Seal; Paul Allen; Mitul A Mehta; James M Stone; Nigel Tunstall; Vincent Giampietro; Shitij Kapur; Robin M Murray; Antonio W Zuardi; José Alexandre de Souza Crippa; Zerrin Atakan; Philip K McGuire
Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(3):764-74.
2010: Min Wang; Lin Pei; Paul J Fletcher; Shitij Kapur; Philip Seeman; Fang Liu
Schizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerization.
Molecular brain 2010;3():25.
2010: Jim van Os; Shitij Kapur
[Psychosis: from diagnosis to syndrome].
Nederlands tijdschrift voor geneeskunde 2010;154():A1874.
2010: Philip Gerretsen; Ariel Graff-Guerrero; Mahesh Menon; Bruce G Pollock; Shitij Kapur; Neil Vasdev; Sylvain Houle; David Mamo
Is desire for social relationships mediated by the serotonergic system in the prefrontal cortex? An [(18)F]setoperone PET study.
Social neuroscience 2010;5(4):375-83.
2010: Jolanta Zanelli; Abraham Reichenberg; Kevin Morgan; Paul Fearon; Eugenia Kravariti; Paola Dazzan; Craig Morgan; Caroline Zanelli; Arsime Demjaha; Peter B Jones; gillian doody; Shitij Kapur; Robin M Murray
Specific and generalized neuropsychological deficits: a comparison of patients with various first-episode psychosis presentations.
The American journal of psychiatry 2010;167(1):78-85.
2010: Bruce J Kinon; Lei Chen; Haya Ascher-Svanum; Virginia L Stauffer; Sara Kollack-Walker; Wei Zhou; Shitij Kapur; John M Kane
Early response to antipsychotic drug therapy as a clinical marker of subsequent response in the treatment of schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(2):581-90.
2010: Terence A Ketter; Ofer Agid; Shitij Kapur; Antony Loebel; Cynthia O Siu; Steven J Romano
Rapid antipsychotic response with ziprasidone predicts subsequent acute manic/mixed episode remission.
Journal of psychiatric research 2010;44(1):8-14.
2009: Hiroyuki Uchida; Tarek K Rajji; Benoit H Mulsant; Shitij Kapur; Bruce G Pollock; Ariel Graff-Guerrero; Mahesh Menon; David Mamo
D2 receptor blockade by risperidone correlates with attention deficits in late-life schizophrenia.
Journal of clinical psychopharmacology 2009;29(6):571-5.
2009: Lieuwe Appel; Yona Geffen; Kerstin Heurling; Catarina Eriksson; Gunnar Antoni; Shitij Kapur
BL-1020, a novel antipsychotic candidate with GABA-enhancing effects: D2 receptor occupancy study in humans.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2009;19(12):841-50.
2009: Patrick McCormick; Shitij Kapur; Greg Reckless; Alan Wilson
Ex vivo [11C]-(+)-PHNO binding is unchanged in animal models displaying increased high-affinity states of the D2 receptor in vitro.
Synapse (New York, N.Y.) 2009;63(11):998-1009.
2009: Robert E Featherstone; Christie L Burton; Romina Coppa-Hopman; Zoë Rizos; Judy Sinyard; Shitij Kapur; Paul Fletcher
Gestational treatment with methylazoxymethanol (MAM) that disrupts hippocampal-dependent memory does not alter behavioural response to cocaine.
Pharmacology, biochemistry, and behavior 2009;93(4):382-90.
2009: Paul D Morrison; V Zois; D A McKeown; T D Lee; David Holt; J F Powell; Shitij Kapur; Robin M Murray
The acute effects of synthetic intravenous Delta9-tetrahydrocannabinol on psychosis, mood and cognitive functioning.
Psychological medicine 2009;39(10):1607-16.
2009: Jim van Os; Shitij Kapur
Schizophrenia.
Lancet 2009;374(9690):635-45.
2009: Usoa E Busto; Laura Redden; Helen S Mayberg; Shitij Kapur; Sylvain Houle; Laurie A Zawertailo
Dopaminergic activity in depressed smokers: a positron emission tomography study.
Synapse (New York, N.Y.) 2009;63(8):681-9.
2009: Guy Goodwin; Wolfgang Fleischhacker; Celso Arango; Pierre Baumann; Michael Davidson; marc de hert; Peter Falkai; Shitij Kapur; Stefan Leucht; Rasmus Licht; Dieter Naber; Veronica O'Keane; George Papakostas; Eduard Vieta; Joseph Zohar
Advantages and disadvantages of combination treatment with antipsychotics ECNP Consensus Meeting, March 2008, Nice.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2009;19(7):520-32.
2009: Ariel Graff-Guerrero; David Mamo; C M Shammi; Romina Mizrahi; Heidi Marcon; Penny Barsoum; Pablo Rusjan; Sylvain Houle; Alan Wilson; Shitij Kapur
The effect of antipsychotics on the high-affinity state of D2 and D3 receptors: a positron emission tomography study With [11C]-(+)-PHNO.
Archives of general psychiatry 2009;66(6):606-15.
2009: Romina Mizrahi; David Mamo; Pablo Rusjan; Ariel Graff-Guerrero; Sylvain Houle; Shitij Kapur
The relationship between subjective well-being and dopamine D2 receptors in patients treated with a dopamine partial agonist and full antagonist antipsychotics.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009;12(5):715-21.
2009: Faïza Benaliouad; Shitij Kapur; Sridhar Natesan; Pierre-Paul Rompré
Effects of the dopamine stabilizer, OSU-6162, on brain stimulation reward and on quinpirole-induced changes in reward and locomotion.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2009;19(6):416-30.
2009: Toby T Winton-Brown; Shitij Kapur
Neuroimaging of schizophrenia: what it reveals about the disease and what it tells us about a patient.
Annals of the Academy of Medicine, Singapore 2009;38(5):433-3.
2009: Oliver D Howes; Shitij Kapur
The dopamine hypothesis of schizophrenia: version III--the final common pathway.
Schizophrenia bulletin 2009;35(3):549-62.
2009: Isabelle Boileau; Mark Guttman; Pablo Rusjan; John R Adams; Sylvain Houle; Junchao Tong; Oleh Hornykiewicz; Yoshiaki Furukawa; Alan Wilson; Shitij Kapur; Stephen J Kish
Decreased binding of the D3 dopamine receptor-preferring ligand [11C]-(+)-PHNO in drug-naive Parkinson's disease.
Brain : a journal of neurology 2009;132(Pt 5):1366-75.
2009: Hiroyuki Uchida; Shitij Kapur; Benoit H Mulsant; Ariel Graff-Guerrero; Bruce G Pollock; David Mamo
Sensitivity of older patients to antipsychotic motor side effects: a PET study examining potential mechanisms.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2009;17(3):255-63.
2009: Hiroyuki Uchida; David Mamo; Benoit H Mulsant; Bruce G Pollock; Shitij Kapur
Increased antipsychotic sensitivity in elderly patients: evidence and mechanisms.
The Journal of clinical psychiatry 2009;70(3):397-405.
2009: Ariel Graff-Guerrero; Romina Mizrahi; Ofer Agid; Heidi Marcon; Penny Barsoum; Pablo Rusjan; Alan Wilson; Robert B Zipursky; Shitij Kapur
The dopamine D2 receptors in high-affinity state and D3 receptors in schizophrenia: a clinical [11C]-(+)-PHNO PET study.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(4):1078-86.
2009: Nathalie Ginovart; Alan Wilson; Doug Hussey; Sylvain Houle; Shitij Kapur
D2-receptor upregulation is dependent upon temporal course of D2-occupancy: a longitudinal [11C]-raclopride PET study in cats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(3):662-71.
2009: O D Howes; A Egerton; V Allan; P McGuire; Paul Stokes; Shitij Kapur
Mechanisms underlying psychosis and antipsychotic treatment response in schizophrenia: insights from PET and SPECT imaging.
Current pharmaceutical design 2009;15(22):2550-9.
2008: Maria J Arranz; Shitij Kapur
Pharmacogenetics in psychiatry: are we ready for widespread clinical use?
Schizophrenia bulletin 2008;34(6):1130-44.
2008: Oliver D Howes; Philip K McGuire; Shitij Kapur
Understanding pathophysiology is crucial in linking clinical staging to targeted therapeutics.
World psychiatry : official journal of the World Psychiatric Association (WPA) 2008;7(3):162-3.
2008: Sridhar Natesan; Greg E Reckless; Karen B L Barlow; José N Nobrega; Shitij Kapur
Amisulpride the 'atypical' atypical antipsychotic--comparison to haloperidol, risperidone and clozapine.
Schizophrenia research 2008;105(1-3):224-35.
2008: Alexa Mead; Ming Li; Shitij Kapur
Clozapine and olanzapine exhibit an intrinsic anxiolytic property in two conditioned fear paradigms: contrast with haloperidol and chlordiazepoxide.
Pharmacology, biochemistry, and behavior 2008;90(4):551-62.
2008: Rajiv Tandon; Ming Tsuang; Avi Weizman; Ziad Kronfol; Hagop Akiskal; Parmesvara Deva; Russell D'Souza; B N Gangadhar; Afzal Javed; Shitij Kapur; Matcheri S Keshavan
Disaster mental health in Asia and the Asian Journal of Psychiatry.
Asian journal of psychiatry 2008;1(1):5-6.
2008: Ofer Agid; Shitij Kapur; Gary Remington
Emerging drugs for schizophrenia.
Expert opinion on emerging drugs 2008;13(3):479-95.
2008: Romina Mizrahi; Jean Addington; Gary Remington; Shitij Kapur
Attribution style as a factor in psychosis and symptom resolution.
Schizophrenia research 2008;104(1-3):220-7.
2008: Hiroyuki Uchida; David Mamo; Shitij Kapur; Alain Labelle; Chekkera Shammi; Erik Mannaert; Steve W Mann; Gary Remington
Monthly administration of long-acting injectable risperidone and striatal dopamine D2 receptor occupancy for the management of schizophrenia.
The Journal of clinical psychiatry 2008;69(8):1281-6.
2008: Sridhar Natesan; Greg E Reckless; Karen B L Barlow; John Odontiadis; José N Nobrega; Glen B Baker; Susan R George; David Mamo; Shitij Kapur
The antipsychotic potential of l-stepholidine--a naturally occurring dopamine receptor D1 agonist and D2 antagonist.
Psychopharmacology 2008;199(2):275-89.
2008: Anne-Noël Samaha; Greg E Reckless; Philip Seeman; Mustansir Diwan; José N Nobrega; Shitij Kapur
Less is more: antipsychotic drug effects are greater with transient rather than continuous delivery.
Biological psychiatry 2008;64(2):145-52.
2008: Ofer Agid; Shitij Kapur; Lewis Warrington; Antony Loebel; Cynthia Siu
Early onset of antipsychotic response in the treatment of acutely agitated patients with psychotic disorders.
Schizophrenia research 2008;102(1-3):241-8.
2008: Robert E Featherstone; Zoe Rizos; Shitij Kapur; Paul Fletcher
A sensitizing regimen of amphetamine that disrupts attentional set-shifting does not disrupt working or long-term memory.
Behavioural brain research 2008;189(1):170-9.
2008: Ariel Graff-Guerrero; Matthäus Willeit; Nathalie Ginovart; David Mamo; Romina Mizrahi; Pablo Rusjan; Irina Vitcu; Philip Seeman; Alan Wilson; Shitij Kapur
Brain region binding of the D2/3 agonist [11C]-(+)-PHNO and the D2/3 antagonist [11C]raclopride in healthy humans.
Human brain mapping 2008;29(4):400-10.
2008: Jimmy Jensen; Matthäus Willeit; Robert B Zipursky; Ioulia Savina; Andrew J Smith; Mahesh Menon; Adrian P Crawley; Shitij Kapur
The formation of abnormal associations in schizophrenia: neural and behavioral evidence.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(3):473-9.
2008: David C Mamo; Hiroyuki Uchida; Irina Vitcu; Penny Barsoum; Alain Gendron; Jeffrey Goldstein; Shitij Kapur
Quetiapine extended-release versus immediate-release formulation: a positron emission tomography study.
The Journal of clinical psychiatry 2008;69(1):81-6.
2008: Patrick McCormick; Shitij Kapur; Philip Seeman; Alan Wilson
Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo.
Nuclear medicine and biology 2008;35(1):11-7.
2008: Mahesh Menon; Romina Mizrahi; Shitij Kapur
'Jumping to conclusions' and delusions in psychosis: relationship and response to treatment.
Schizophrenia research 2008;98(1-3):225-31.
2008: David Mamo; Shitij Kapur; Matcheri S Keshavan; Marc Laruelle; Cindy C Taylor; Prajakti A Kothare; Penny Barsoum; David McDonnell
D2 receptor occupancy of olanzapine pamoate depot using positron emission tomography: an open-label study in patients with schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(2):298-304.
2008: Matthäus Willeit; Nathalie Ginovart; Ariel Graff-Guerrero; Pablo Rusjan; Irina Vitcu; Sylvain Houle; Philip Seeman; Alan Wilson; Shitij Kapur
First human evidence of d-amphetamine induced displacement of a D2/3 agonist radioligand: A [11C]-(+)-PHNO positron emission tomography study.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(2):279-89.
2007: Imran Chaudhry; Nusrat Husain; Salahuddin Khan; Sareer Badshah; Bill Deakin; Shitij Kapur
Amoxapine as an antipsychotic: comparative study versus haloperidol.
Journal of clinical psychopharmacology 2007;27(6):575-81.
2007: R E Featherstone; Shitij Kapur; Paul Fletcher
The amphetamine-induced sensitized state as a model of schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry 2007;31(8):1556-71.
2007: Krista L Lanctôt; Doug F Hussey; Nathan Herrmann; Sandra Black; Pablo Rusjan; Alan Wilson; Sylvain Houle; Nicole Kozloff; Nicolaas P L G Verhoeff; Shitij Kapur
A positron emission tomography study of 5-hydroxytryptamine-1A receptors in Alzheimer disease.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2007;15(10):888-98.
2007: Mahesh Menon; Jimmy Jensen; Irina Vitcu; Ariel Graff-Guerrero; Adrian P Crawley; Mark A Smith; Shitij Kapur
Temporal difference modeling of the blood-oxygen level dependent response during aversive conditioning in humans: effects of dopaminergic modulation.
Biological psychiatry 2007;62(7):765-72.
2007: David Mamo; Ariel Graff-Guerrero; Romina Mizrahi; Chekkera Shammi; Françoise Romeyer; Shitij Kapur
Differential effects of aripiprazole on D(2), 5-HT(2), and 5-HT(1A) receptor occupancy in patients with schizophrenia: a triple tracer PET study.
The American journal of psychiatry 2007;164(9):1411-7.
2007: Ofer Agid; Gary Remington; Shitij Kapur; Tamara Arenovich; Robert B Zipursky
Early use of clozapine for poorly responding first-episode psychosis.
Journal of clinical psychopharmacology 2007;27(4):369-73.
2007: Sridhar Natesan; Greg E Reckless; Karen B L Barlow; José N Nobrega; Shitij Kapur
Evaluation of N-desmethylclozapine as a potential antipsychotic--preclinical studies.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(7):1540-9.
2007: Ofer Agid; David Mamo; Nathalie Ginovart; Irina Vitcu; Alan Wilson; Robert B Zipursky; Shitij Kapur
Striatal vs extrastriatal dopamine D2 receptors in antipsychotic response--a double-blind PET study in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(6):1209-15.
2007: Philip Seeman; Patrick N McCormick; Shitij Kapur
Increased dopamine D2(High) receptors in amphetamine-sensitized rats, measured by the agonist [(3)H](+)PHNO.
Synapse (New York, N.Y.) 2007;61(5):263-7.
2007: John Odontiadis; Erin M MacKenzie; Sridhar Natesan; David Mamo; Shitij Kapur; Glen B Baker
Quantification of l-stepholidine in rat brain and plasma by high performance liquid chromatography combined with fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;850(1-2):544-7.
2007: Paul Fletcher; Catherine C Tenn; Judy Sinyard; Zoë Rizos; Shitij Kapur
A sensitizing regimen of amphetamine impairs visual attention in the 5-choice serial reaction time test: reversal by a D1 receptor agonist injected into the medial prefrontal cortex.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(5):1122-32.
2007: Romina Mizrahi; Pablo Rusjan; Ofer Agid; Ariel Graff-Guerrero; David Mamo; Robert B Zipursky; Shitij Kapur
Adverse subjective experience with antipsychotics and its relationship to striatal and extrastriatal D2 receptors: a PET study in schizophrenia.
The American journal of psychiatry 2007;164(4):630-7.
2007: Romina Mizrahi; Michele Korostil; Sergio E Starkstein; Robert B Zipursky; Shitij Kapur
The effect of antipsychotic treatment on Theory of Mind.
Psychological medicine 2007;37(4):595-601.
2007: Nathalie Ginovart; Matthäus Willeit; Pablo Rusjan; Ariel Graff-Guerrero; Peter M Bloomfield; Sylvain Houle; Shitij Kapur; Alan Wilson
Positron emission tomography quantification of [11C]-(+)-PHNO binding in the human brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(4):857-71.
2007: Jimmy Jensen; Andrew J Smith; Matthäus Willeit; Adrian P Crawley; David J Mikulis; Irina Vitcu; Shitij Kapur
Separate brain regions code for salience vs. valence during reward prediction in humans.
Human brain mapping 2007;28(4):294-302.
2007: Anne-Noël Samaha; Philip Seeman; Jane Stewart; Heshmat Rajabi; Shitij Kapur
"Breakthrough" dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(11):2979-86.
2007: Faïza Benaliouad; Shitij Kapur; Pierre-Paul Rompré
Blockade of 5-HT2a receptors reduces haloperidol-induced attenuation of reward.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(3):551-61.
2007: Robert E Featherstone; Zoë Rizos; José N Nobrega; Shitij Kapur; Paul Fletcher
Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(2):483-92.
2007: Ming Li; Paul Fletcher; Shitij Kapur
Time course of the antipsychotic effect and the underlying behavioral mechanisms.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(2):263-72.
2007: Andrew J Smith; Ming Li; Suzanna Becker; Shitij Kapur
Linking animal models of psychosis to computational models of dopamine function.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(1):54-66.
2006: Romina Mizrahi; Michael Kiang; David Mamo; Tamara Arenovich; R Michael Bagby; Robert B Zipursky; Shitij Kapur
The selective effect of antipsychotics on the different dimensions of the experience of psychosis in schizophrenia spectrum disorders.
Schizophrenia research 2006;88(1-3):111-8.
2006: Marci L Chew; Benoit H Mulsant; Bruce G Pollock; Mark E Lehman; Andrew Greenspan; Margaret A Kirshner; Robert R Bies; Shitij Kapur; Georges Gharabawi
A model of anticholinergic activity of atypical antipsychotic medications.
Schizophrenia research 2006;88(1-3):63-72.
2006: Philip Seeman; Alan Wilson; Peter Gmeiner; Shitij Kapur
Dopamine D2 and D3 receptors in human putamen, caudate nucleus, and globus pallidus.
Synapse (New York, N.Y.) 2006;60(3):205-11.
2006: Sridhar Natesan; Greg E Reckless; José N Nobrega; Paul Fletcher; Shitij Kapur
Dissociation between in vivo occupancy and functional antagonism of dopamine D2 receptors: comparing aripiprazole to other antipsychotics in animal models.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(9):1854-63.
2006: Laurent Galineau; Alan Wilson; Armando Garcia; Sylvain Houle; Shitij Kapur; Nathalie Ginovart
In vivo characterization of the pharmacokinetics and pharmacological properties of [11C]-(+)-PHNO in rats using an intracerebral beta-sensitive system.
Synapse (New York, N.Y.) 2006;60(2):172-83.
2006: Sridhar Natesan; Kjell A Svensson; Greg E Reckless; José N Nobrega; Karen B L Barlow; Anette M Johansson; Shitij Kapur
The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat.
The Journal of pharmacology and experimental therapeutics 2006;318(2):810-8.
2006: Pablo Rusjan; David Mamo; Nathalie Ginovart; Doug Hussey; Irina Vitcu; Fumihiko Yasuno; Suhara Tetsuya; Sylvain Houle; Shitij Kapur
An automated method for the extraction of regional data from PET images.
Psychiatry research 2006;147(1):79-89.
2006: Nathalie Ginovart; Laurent Galineau; Matthäus Willeit; Romina Mizrahi; Peter M Bloomfield; Philip Seeman; Sylvain Houle; Shitij Kapur; Alan Wilson
Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography.
Journal of neurochemistry 2006;97(4):1089-103.
2006: Andrew Smith; Ming Li; Sue Becker; Shitij Kapur
Dopamine, prediction error and associative learning: a model-based account.
Network (Bristol, England) 2006;17(1):61-84.
2006: Ofer Agid; Philip Seeman; Shitij Kapur
The "delayed onset" of antipsychotic action--an idea whose time has come and gone.
Journal of psychiatry & neuroscience : JPN 2006;31(2):93-100.
2006: Gary Remington; David Mamo; Alain Labelle; Jeffrey Reiss; Chekkera Shammi; Erik Mannaert; Steve Mann; Shitij Kapur
A PET study evaluating dopamine D2 receptor occupancy for long-acting injectable risperidone.
The American journal of psychiatry 2006;163(3):396-401.
2006: Matthäus Willeit; Nathalie Ginovart; Shitij Kapur; Sylvain Houle; Doug Hussey; Philip Seeman; Alan Wilson
High-affinity states of human brain dopamine D2/3 receptors imaged by the agonist [11C]-(+)-PHNO.
Biological psychiatry 2006;59(5):389-94.
2006: Shitij Kapur; Ofer Agid; Romina Mizrahi; Ming Li
How antipsychotics work-from receptors to reality.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2006;3(1):10-21.
2005: Gary Remington; Shitij Kapur
Remission: what's in a name?
The American journal of psychiatry 2005;162(12):2393-4; author reply 2394.
2005: Gary Remington; Philip Seeman; Chekkera Shammi; Steve Mann; Shitij Kapur
"Extended" antipsychotic dosing: rationale and pilot data.
Journal of clinical psychopharmacology 2005;25(6):611-3.
2005: Paul Fletcher; Catherine C Tenn; Zoë Rizos; Vedran Lovic; Shitij Kapur
Sensitization to amphetamine, but not PCP, impairs attentional set shifting: reversal by a D1 receptor agonist injected into the medial prefrontal cortex.
Psychopharmacology 2005;183(2):190-200.
2005: Rogelio Apiquian; Ana Fresan; Rosa-Elena Ulloa; Camilo de la Fuente-Sandoval; Miguel Herrera-Estrella; Alejandra Vazquez; Humberto Nicolini; Shitij Kapur
Amoxapine as an atypical antipsychotic: a comparative study vs risperidone.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(12):2236-44.
2005: Shitij Kapur; Romina Mizrahi; Ming Li
From dopamine to salience to psychosis--linking biology, pharmacology and phenomenology of psychosis.
Schizophrenia research 2005;79(1):59-68.
2005: Sridhar Natesan; Susan C VanderSpek; José N Nobrega; Robert A McClelland; Shitij Kapur
Contrasting loxapine to its isomer isoloxapine--the critical role of in vivo D2 blockade in determining atypicality.
Schizophrenia research 2005;77(2-3):189-99.
2005: Ming Li; Radek Budin; Alison S Fleming; Shitij Kapur
Effects of novel antipsychotics, amisulpiride and aripiprazole, on maternal behavior in rats.
Psychopharmacology 2005;181(3):600-10.
2005: Robert B Zipursky; Bruce K Christensen; Zafiris J Daskalakis; Irvin Epstein; Paul Roy; Ivana Furimsky; Todd Sanger; Shitij Kapur
Treatment response to olanzapine and haloperidol and its association with dopamine D receptor occupancy in first-episode psychosis.
Canadian journal of psychiatry. Revue canadienne de psychiatrie 2005;50(8):462-9.
2005: Catherine C Tenn; Shitij Kapur; Paul Fletcher
Sensitization to amphetamine, but not phencyclidine, disrupts prepulse inhibition and latent inhibition.
Psychopharmacology 2005;180(2):366-76.
2005: Alan Wilson; Patrick McCormick; Shitij Kapur; Matthäus Willeit; Armando Garcia; Doug Hussey; Sylvain Houle; Philip Seeman; Nathalie Ginovart
Radiosynthesis and evaluation of [11C]-(+)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a potential radiotracer for in vivo imaging of the dopamine D2 high-affinity state with positron emission tomography.
Journal of medicinal chemistry 2005;48(12):4153-60.
2005: Tod E Kippin; Shitij Kapur; Derek van der Kooy
Dopamine specifically inhibits forebrain neural stem cell proliferation, suggesting a novel effect of antipsychotic drugs.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(24):5815-23.
2005: Ming Li; Radek Budin; Alison S Fleming; Shitij Kapur
Effects of chronic typical and atypical antipsychotic drug treatment on maternal behavior in rats.
Schizophrenia research 2005;75(2-3):325-36.
2005: Romina Mizrahi; R Michael Bagby; Robert B Zipursky; Shitij Kapur
How antipsychotics work: the patients' perspective.
Progress in neuro-psychopharmacology & biological psychiatry 2005;29(5):859-64.
2005: Shitij Kapur; Tamara Arenovich; Ofer Agid; Robert B Zipursky; Stacy Lindborg; Barry Jones
Evidence for onset of antipsychotic effects within the first 24 hours of treatment.
The American journal of psychiatry 2005;162(5):939-46.
2005: Catherine C Tenn; Paul Fletcher; Shitij Kapur
A putative animal model of the "prodromal" state of schizophrenia.
Biological psychiatry 2005;57(6):586-93.
2005: Peter Turrone; Gary Remington; Shitij Kapur; José N Nobrega
Continuous but not intermittent olanzapine infusion induces vacuous chewing movements in rats.
Biological psychiatry 2005;57(4):406-11.
2005: Andrew James Smith; Suzanna Becker; Shitij Kapur
A computational model of the functional role of the ventral-striatal D2 receptor in the expression of previously acquired behaviors.
Neural computation 2005;17(2):361-95.
2004: Johannes Tauscher; Tabasum Hussain; Ofer Agid; Nicolaas P L G Verhoeff; Alan Wilson; Sylvain Houle; Gary Remington; Robert B Zipursky; Shitij Kapur
Equivalent occupancy of dopamine D1 and D2 receptors with clozapine: differentiation from other atypical antipsychotics.
The American journal of psychiatry 2004;161(9):1620-5.
2004: Ming Li; Patty Davidson; Radek Budin; Shitij Kapur; Alison S Fleming
Effects of typical and atypical antipsychotic drugs on maternal behavior in postpartum female rats.
Schizophrenia research 2004;70(1):69-80.
2004: David Mamo; Ewen Sedman; Joachim Tillner; Edward M Sellers; Myroslava K Romach; Shitij Kapur
EMD 281014, a specific and potent 5HT2 antagonist in humans: a dose-finding PET study.
Psychopharmacology 2004;175(3):382-8.
2004: Ming Li; Jun Parkes; Paul Fletcher; Shitij Kapur
Evaluation of the motor initiation hypothesis of APD-induced conditioned avoidance decreases.
Pharmacology, biochemistry, and behavior 2004;78(4):811-9.
2004: Shitij Kapur
How antipsychotics become anti-"psychotic"--from dopamine to salience to psychosis.
Trends in pharmacological sciences 2004;25(8):402-6.
2004: Paul B Fitzgerald; Sacha L Filia; Anthony de Castella; Nicole McBain; Shitij Kapur; Jayashri Kulkarni
Amoxapine in schizophrenia: a negative double-blind controlled trial.
Journal of clinical psychopharmacology 2004;24(4):448-50.
2004: Nathalie Ginovart; Alan Wilson; Sylvain Houle; Shitij Kapur
Amphetamine pretreatment induces a change in both D2-Receptor density and apparent affinity: a [11C]raclopride positron emission tomography study in cats.
Biological psychiatry 2004;55(12):1188-94.
2004: Akihiro Takano; Tetsuya Suhara; Jun Maeda; Kiyoshi Ando; Takashi Okauchi; Shigeru Obayashi; Takashi Nakayama; Shitij Kapur
Relation between cortical dopamine D(2) receptor occupancy and suppression of conditioned avoidance response in non-human primate.
Psychiatry and clinical neurosciences 2004;58(3):330-2.
2004: Andrew Smith; Ming Li; Sue Becker; Shitij Kapur
A model of antipsychotic action in conditioned avoidance: a computational approach.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(6):1040-9.
2004: David Mamo; Shitij Kapur; Chekkera Shammi; George Papatheodorou; Steve Mann; François Therrien; Gary Remington
A PET study of dopamine D2 and serotonin 5-HT2 receptor occupancy in patients with schizophrenia treated with therapeutic doses of ziprasidone.
The American journal of psychiatry 2004;161(5):818-25.
2004: David Mamo; Gary Remington; José N Nobrega; Doug Hussey; Raman Chirakal; Alan Wilson; Glen Baker; Sylvain Houle; Shitij Kapur
Effect of acute antipsychotic administration on dopamine synthesis in rodents and human subjects using 6-[18F]-L-m-tyrosine.
Synapse (New York, N.Y.) 2004;52(2):153-62.
2004: Nathalie Ginovart; Wenshan Sun; Alan Wilson; Sylvain Houle; Shitij Kapur
Quantitative validation of an intracerebral beta-sensitive microprobe system to determine in vivo drug-induced receptor occupancy using [11C]raclopride in rats.
Synapse (New York, N.Y.) 2004;52(2):89-99.
2004: Laura Cárdenas; Sylvain Houle; Shitij Kapur; Usoa E Busto
Oral D-amphetamine causes prolonged displacement of [11C]raclopride as measured by PET.
Synapse (New York, N.Y.) 2004;51(1):27-31.
2003: Jimmy Jensen; Anthony R McIntosh; Adrian P Crawley; David J Mikulis; Gary Remington; Shitij Kapur
Direct activation of the ventral striatum in anticipation of aversive stimuli.
Neuron 2003;40(6):1251-7.
2003: Ofer Agid; Shitij Kapur; Tamara Arenovich; Robert B Zipursky
Delayed-onset hypothesis of antipsychotic action: a hypothesis tested and rejected.
Archives of general psychiatry 2003;60(12):1228-35.
2003: Catherine C Tenn; Paul Fletcher; Shitij Kapur
Amphetamine-sensitized animals show a sensorimotor gating and neurochemical abnormality similar to that of schizophrenia.
Schizophrenia research 2003;64(2-3):103-14.
2003: Aviva Abosch; Shitij Kapur; Anthony E Lang; Doug Hussey; Elspeth Sime; Janis M Miyasaki; Sylvain Houle; Andres M Lozano
Stimulation of the subthalamic nucleus in Parkinson's disease does not produce striatal dopamine release.
Neurosurgery 2003;53(5):1095-102; discussion 1102-5.
2003: Zafiris J Daskalakis; Bruce K Christensen; Robert Chen; Paul B Fitzgerald; Robert B Zipursky; Shitij Kapur
Effect of antipsychotics on cortical inhibition using transcranial magnetic stimulation.
Psychopharmacology 2003;170(3):255-62.
2003: Shitij Kapur; David Mamo
Half a century of antipsychotics and still a central role for dopamine D2 receptors.
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(7):1081-90.
2003: Philip Seeman; Shitij Kapur
Anesthetics inhibit high-affinity states of dopamine D2 and other G-linked receptors.
Synapse (New York, N.Y.) 2003;50(1):35-40.
2003: Michael Kiang; Bruce K Christensen; Gary Remington; Shitij Kapur
Apathy in schizophrenia: clinical correlates and association with functional outcome.
Schizophrenia research 2003;63(1-2):79-88.
2003: Peter Turrone; Gary Remington; Shitij Kapur; José N Nobrega
Differential effects of within-day continuous vs. transient dopamine D2 receptor occupancy in the development of vacuous chewing movements (VCMs) in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(8):1433-9.
2003: Michael Kiang; Zafiris J Daskalakis; Bruce K Christensen; Gary Remington; Shitij Kapur
Actigraphic measurement of the effects of single-dose haloperidol and olanzapine on spontaneous motor activity in normal subjects.
Journal of psychiatry & neuroscience : JPN 2003;28(4):293-9.
2003: Shitij Kapur; Susan C VanderSpek; Barbara A Brownlee; José N Nobrega
Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy.
The Journal of pharmacology and experimental therapeutics 2003;305(2):625-31.
2003: W Sun; Nathalie Ginovart; F Ko; Philip Seeman; Shitij Kapur
In vivo evidence for dopamine-mediated internalization of D2-receptors after amphetamine: differential findings with [3H]raclopride versus [3H]spiperone.
Molecular pharmacology 2003;63(2):456-62.
2003: Shitij Kapur
Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia.
The American journal of psychiatry 2003;160(1):13-23.
2003: Nicolaas P L G Verhoeff; Bruce K Christensen; Doug Hussey; Maggie Lee; George Papatheodorou; Lili C Kopala; Qing Rui; Robert B Zipursky; Shitij Kapur
Effects of catecholamine depletion on D2 receptor binding, mood, and attentiveness in humans: a replication study.
Pharmacology, biochemistry, and behavior 2003;74(2):425-32.
2003: Peter Turrone; Gary Remington; Shitij Kapur; José N Nobrega
The relationship between dopamine D2 receptor occupancy and the vacuous chewing movement syndrome in rats.
Psychopharmacology 2003;165(2):166-71.
2003: Rogelio Apiquian; Elena Ulloa; Ana Fresan; Cristina Loyzaga; Humberto Nicolini; Shitij Kapur
Amoxapine shows atypical antipsychotic effects in patients with schizophrenia: results from a prospective open-label study.
Schizophrenia research 2003;59(1):35-9.
2002: Philip Seeman; Teresa Tallerico; Françoise Ko; Catherine Tenn; Shitij Kapur
Amphetamine-sensitized animals show a marked increase in dopamine D2 high receptors occupied by endogenous dopamine, even in the absence of acute challenges.
Synapse (New York, N.Y.) 2002;46(4):235-9.
2002: Sitra Tauscher-Wisniewski; Shitij Kapur; Johannes Tauscher; Corey Jones; Zafiris J Daskalakis; George Papatheodorou; Irvin Epstein; Bruce K Christensen; Robert B Zipursky
Quetiapine: an effective antipsychotic in first-episode schizophrenia despite only transiently high dopamine-2 receptor blockade.
The Journal of clinical psychiatry 2002;63(11):992-7.
2002: Shitij Kapur; Xavier Langlois; P Vinken; Anton Megens; R De Coster; J S Andrews
The differential effects of atypical antipsychotics on prolactin elevation are explained by their differential blood-brain disposition: a pharmacological analysis in rats.
The Journal of pharmacology and experimental therapeutics 2002;302(3):1129-34.
2002: Gary Remington; Shitij Kapur
Review: amisulpride is effective and safe for schizophrenia.
Evidence-based mental health 2002;5(3):85.
2002: Françoise Ko; Philip Seeman; W S Sun; Shitij Kapur
Dopamine D2 receptors internalize in their low-affinity state.
Neuroreport 2002;13(8):1017-20.
2002: Johannes Tauscher; Shitij Kapur; Nicolaas P L G Verhoeff; Doug F Hussey; Zafiris J Daskalakis; Sitra Tauscher-Wisniewski; Alan Wilson; Sylvain Houle; Siegfried Kasper; Robert B Zipursky
Brain serotonin 5-HT(1A) receptor binding in schizophrenia measured by positron emission tomography and [11C]WAY-100635.
Archives of general psychiatry 2002;59(6):514-20.
2002: Shitij Kapur; Robert A McClelland; Susan C VanderSpek; Marie-Louise G Wadenberg; Glen Baker; José N Nobrega; Robert B Zipursky; Philip Seeman
Increasing D2 affinity results in the loss of clozapine's atypical antipsychotic action.
Neuroreport 2002;13(6):831-5.
2002: Shitij Kapur; Philip Seeman
Atypical antipsychotics, cortical D(2) receptors and sensitivity to endogenous dopamine.
The British journal of psychiatry : the journal of mental science 2002;180():465-6.
2002: Zafiris J Daskalakis; Bruce K Christensen; Robert Chen; Paul B Fitzgerald; Robert B Zipursky; Shitij Kapur
Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation.
Archives of general psychiatry 2002;59(4):347-54.
2002: Tetsuya Suhara; Takashi Okauchi; Yasuhiko Sudo; Akihiro Takano; Kouichi Kawabe; Jun Maeda; Shitij Kapur
Clozapine can induce high dopamine D(2) receptor occupancy in vivo.
Psychopharmacology 2002;160(1):107-12.
2002: Shitij Kapur; Philip Seeman
NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia.
Molecular psychiatry 2002;7(8):837-44.
2002: Nicolaas P L G Verhoeff; Doug Hussey; Maggie Lee; Johannes Tauscher; George Papatheodorou; Alan Wilson; Sylvain Houle; Shitij Kapur
Dopamine depletion results in increased neostriatal D(2), but not D(1), receptor binding in humans.
Molecular psychiatry 2002;7(3):233, 322-8.
2002: Johannes Tauscher; C Jones; Gary Remington; Robert B Zipursky; Shitij Kapur
Significant dissociation of brain and plasma kinetics with antipsychotics.
Molecular psychiatry 2002;7(3):317-21.
2002: Peter Turrone; Shitij Kapur; Mary V Seeman; Alastair J Flint
Elevation of prolactin levels by atypical antipsychotics.
The American journal of psychiatry 2002;159(1):133-5.
2001: Shitij Kapur; Gary Remington
Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient.
Biological psychiatry 2001;50(11):873-83.
2001: Marie-Louise G Wadenberg; A Soliman; Susan C VanderSpek; Shitij Kapur
Dopamine D(2) receptor occupancy is a common mechanism underlying animal models of antipsychotics and their clinical effects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(5):633-41.
2001: Shitij Kapur; Karen B L Barlow; Susan C VanderSpek; M Javanmard; José N Nobrega
Drug-induced receptor occupancy: substantial differences in measurements made in vivo vs ex vivo.
Psychopharmacology 2001;157(2):168-71.
2001: Johannes Tauscher; R M Bagby; M Javanmard; Bruce K Christensen; Siegfried Kasper; Shitij Kapur
Inverse relationship between serotonin 5-HT(1A) receptor binding and anxiety: a [(11)C]WAY-100635 PET investigation in healthy volunteers.
The American journal of psychiatry 2001;158(8):1326-8.
2001: Nicolaas P L G Verhoeff; Shitij Kapur; Doug Hussey; Maggie Lee; B Christensen; George Papatheodorou; Robert B Zipursky
A simple method to measure baseline occupancy of neostriatal dopamine D2 receptors by dopamine in vivo in healthy subjects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(2):213-23.
2001: G Remington; Shitij Kapur
SB-277011 GlaxoSmithKline.
Current opinion in investigational drugs (London, England : 2000) 2001;2(7):946-9.
2001: D S Sa; Shitij Kapur; Anthony E Lang
Amoxapine shows an antipsychotic effect but worsens motor function in patients with Parkinson's disease and psychosis.
Clinical neuropharmacology 2001;24(4):242-4.
2001: Shitij Kapur; Philip Seeman
Ketamine has equal affinity for NMDA receptors and the high-affinity state of the dopamine D2 receptor.
Biological psychiatry 2001;49(11):954-7.
2001: Johannes Tauscher; Nicolaas P L G Verhoeff; Bruce K Christensen; Doug Hussey; Jeffrey H Meyer; A Kecojevic; M Javanmard; S Kasper; Shitij Kapur
Serotonin 5-HT1A receptor binding potential declines with age as measured by [11C]WAY-100635 and PET.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;24(5):522-30.
2001: Shitij Kapur; Philip Seeman
Does fast dissociation from the dopamine d(2) receptor explain the action of atypical antipsychotics?: A new hypothesis.
The American journal of psychiatry 2001;158(3):360-9.
2001: Shitij Kapur; P Roy; J Daskalakis; G Remington; R Zipursky
Increased dopamine d(2) receptor occupancy and elevated prolactin level associated with addition of haloperidol to clozapine.
The American journal of psychiatry 2001;158(2):311-4.
2001: Johannes Tauscher; Shitij Kapur
Choosing the right dose of antipsychotics in schizophrenia: lessons from neuroimaging studies.
CNS drugs 2001;15(9):671-8.
2001: Shitij Kapur; Gary Remington
Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia.
Annual review of medicine 2001;52():503-17.
2001: Jeffrey H Meyer; Shitij Kapur; Beata S Eisfeld; Gregory Brown; Sylvain Houle; Jean N DaSilva; Alan Wilson; Shahryar Rafi-Tari; Helen S Mayberg; Sidney H Kennedy
The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study.
The American journal of psychiatry 2001;158(1):78-85.
2000: Shitij Kapur; G Remington
Atypical antipsychotics.
BMJ (Clinical research ed.) 2000;321(7273):1360-1.
2000: Shitij Kapur; S C Barsoum; Philip Seeman
Dopamine D(2) receptor blockade by haloperidol. (3)H-raclopride reveals much higher occupancy than EEDQ.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(5):595-8.
2000: Nicolaas P L G Verhoeff; Jeffrey H Meyer; A Kecojevic; Doug Hussey; R Lewis; Johannes Tauscher; Robert B Zipursky; Shitij Kapur
A voxel-by-voxel analysis of [18F]setoperone PET data shows no substantial serotonin 5-HT(2A) receptor changes in schizophrenia.
Psychiatry research 2000;99(3):123-35.
2000: S Silvestri; Mary V Seeman; Juan C Negrete; Sylvain Houle; Chekkera Shammi; Gary Remington; Shitij Kapur; Robert B Zipursky; Alan Wilson; Bruce K Christensen; Philip Seeman
Increased dopamine D2 receptor binding after long-term treatment with antipsychotics in humans: a clinical PET study.
Psychopharmacology 2000;152(2):174-80.
2000: Nicole D Anderson; T Iidaka; Roberto Cabeza; Shitij Kapur; Anthony R McIntosh; Fergus I M Craik
The effects of divided attention on encoding- and retrieval-related brain activity: A PET study of younger and older adults.
Journal of cognitive neuroscience 2000;12(5):775-92.
2000: Luc F de Nil; Robert M Kroll; Shitij Kapur; Sylvain Houle
A positron emission tomography study of silent and oral single word reading in stuttering and nonstuttering adults.
Journal of speech, language, and hearing research : JSLHR 2000;43(4):1038-53.
2000: Philip Seeman; Shitij Kapur
Schizophrenia: more dopamine, more D2 receptors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(14):7673-5.
2000: Marie-Louise G Wadenberg; Shitij Kapur; A Soliman; C Jones; Franco J Vaccarino
Dopamine D2 receptor occupancy predicts catalepsy and the suppression of conditioned avoidance response behavior in rats.
Psychopharmacology 2000;150(4):422-9.
2000: Shitij Kapur; Robert B Zipursky; C Jones; C S Shammi; Gary Remington; Philip Seeman
A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy.
Archives of general psychiatry 2000;57(6):553-9.
2000: Shitij Kapur; Marie-Louise G Wadenberg; Gary Remington
Are animal studies of antipsychotics appropriately dosed? Lessons from the bedside to the bench.
Canadian journal of psychiatry. Revue canadienne de psychiatrie 2000;45(3):241-6.
2000: M G Wadenberg; TL Sills; Paul Fletcher; Shitij Kapur
Antipsychoticlike effects of amoxapine, without catalepsy, using the prepulse inhibition of the acoustic startle reflex test in rats.
Biological psychiatry 2000;47(7):670-6.
2000: Shitij Kapur; Robert B Zipursky; C Jones; Gary Remington; Sylvain Houle
Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia.
The American journal of psychiatry 2000;157(4):514-20.
2000: P B Fitzgerald; Shitij Kapur; G Remington; P Roy; R B Zipursky
Predicting haloperidol occupancy of central dopamine D2 receptors from plasma levels.
Psychopharmacology 2000;149(1):1-5.
2000: T Iidaka; Nicole D Anderson; Shitij Kapur; Roberto Cabeza; Fergus I M Craik
The effect of divided attention on encoding and retrieval in episodic memory revealed by positron emission tomography.
Journal of cognitive neuroscience 2000;12(2):267-80.
2000: Shitij Kapur; Philip Seeman
Antipsychotic agents differ in how fast they come off the dopamine D2 receptors. Implications for atypical antipsychotic action.
Journal of psychiatry & neuroscience : JPN 2000;25(2):161-6.
2000: Gary Remington; Shitij Kapur
Atypical antipsychotics: are some more atypical than others?
Psychopharmacology 2000;148(1):3-15.
2000: P B Fitzgerald; Shitij Kapur; M P Caligiuri; C Jones; S Silvestri; G Remington; R B Zipursky
Instrumentally detected changes in motor functioning in patients with low levels of antipsychotic dopamine D2 blockade.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(1):19-26.
1999: Jeffrey H Meyer; Shitij Kapur; Sylvain Houle; Jean N DaSilva; B Owczarek; Gregory Brown; Alan Wilson; Sidney H Kennedy
Prefrontal cortex 5-HT2 receptors in depression: an [18F]setoperone PET imaging study.
The American journal of psychiatry 1999;156(7):1029-34.
1999: Gary Remington; S A Chong; Shitij Kapur
Distinguishing change in primary and secondary negative symptoms.
The American journal of psychiatry 1999;156(6):974-5.
1999: Shitij Kapur; R Cho; C Jones; G McKay; R B Zipursky
Is amoxapine an atypical antipsychotic? Positron-emission tomography investigation of its dopamine2 and serotonin2 occupancy.
Biological psychiatry 1999;45(9):1217-20.
1999: R Cho; Shitij Kapur; L Du; P Hrdina
Relationship between central and peripheral serotonin 5-HT2A receptors: a positron emission tomography study in healthy individuals.
Neuroscience letters 1999;261(3):139-42.
1999: Shitij Kapur; Robert B Zipursky; Gary Remington
Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia.
The American journal of psychiatry 1999;156(2):286-93.
1999: G Remington; Shitij Kapur
D2 and 5-HT2 receptor effects of antipsychotics: bridging basic and clinical findings using PET.
The Journal of clinical psychiatry 1999;60 Suppl 10():15-9.
1999: R Lewis; Shitij Kapur; C Jones; Jean N DaSilva; Gregory Brown; Alan Wilson; Sylvain Houle; Robert B Zipursky
Serotonin 5-HT2 receptors in schizophrenia: a PET study using [18F]setoperone in neuroleptic-naive patients and normal subjects.
The American journal of psychiatry 1999;156(1):72-8.
1998: Gary Remington; Shitij Kapur; Robert B Zipursky
APA Practice Guideline for schizophrenia: risperidone equivalents. American Psychiatric Association.
The American journal of psychiatry 1998;155(9):1301-2.
1998: Shitij Kapur; R B Zipursky
Do loxapine plus cyproheptadine make an atypical antipsychotic? PET analysis of their dopamine D2 and serotonin2 receptor occupancy.
Archives of general psychiatry 1998;55(7):666-8.
1998: Shitij Kapur; Robert B Zipursky; Gary Remington; C Jones; Jean N DaSilva; Alan Wilson; Sylvain Houle
5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: a PET investigation.
The American journal of psychiatry 1998;155(7):921-8.
1998: JM Jennings; Anthony R McIntosh; Shitij Kapur; R B Zipursky; Sylvain Houle
Functional network differences in schizophrenia: a rCBF study of semantic processing.
Neuroreport 1998;9(8):1697-700.
1998: Robert B Zipursky; Evelyn K Lambe; Shitij Kapur; DJ Mikulis
Cerebral gray matter volume deficits in first episode psychosis.
Archives of general psychiatry 1998;55(6):540-6.
1998: M Natasha Rajah; D Hussey; Sylvain Houle; Shitij Kapur; Anthony R McIntosh
Task-independent effect of time on rCBF.
NeuroImage 1998;7(4 Pt 1):314-25.
1998: JM Jennings; Anthony R McIntosh; Shitij Kapur
Mapping neural interactivity onto regional activity: an analysis of semantic processing and response mode interactions.
NeuroImage 1998;7(3):244-54.
1998: Shitij Kapur
A new framework for investigating antipsychotic action in humans: lessons from PET imaging.
Molecular psychiatry 1998;3(2):135-40.
1998: Gary Remington; Shitij Kapur; Robert B Zipursky
The relationship between risperidone plasma levels and dopamine D2 occupancy: a positron emission tomographic study.
Journal of clinical psychopharmacology 1998;18(1):82-3.
1998: Gary Remington; Shitij Kapur; Robert B Zipursky
Pharmacotherapy of first-episode schizophrenia.
The British journal of psychiatry. Supplement 1998;172(33):66-70.
1997: Shitij Kapur; Robert B Zipursky; Gary Remington; C Jones; G McKay; Sylvain Houle
PET evidence that loxapine is an equipotent blocker of 5-HT2 and D2 receptors: implications for the therapeutics of schizophrenia.
The American journal of psychiatry 1997;154(11):1525-9.
1997: Shitij Kapur; R B Zipursky; C Jones; Alan Wilson; J D DaSilva; S Houle
Cyproheptadine: a potent in vivo serotonin antagonist.
The American journal of psychiatry 1997;154(6):884.
1997: Shitij Kapur; Robert B Zipursky; P Roy; C Jones; Gary Remington; K Reed; Sylvain Houle
The relationship between D2 receptor occupancy and plasma levels on low dose oral haloperidol: a PET study.
Psychopharmacology 1997;131(2):148-52.
1997: Shitij Kapur; C Jones; Jean N DaSilva; Alan Wilson; Sylvain Houle
Reliability of a simple non-invasive method for the evaluation of 5-HT2 receptors using [18F]-setoperone PET imaging.
Nuclear medicine communications 1997;18(5):395-9.
1997: JM Jennings; Anthony R McIntosh; Shitij Kapur; Endel Tulving; Sylvain Houle
Cognitive subtractions may not add up: the interaction between semantic processing and response mode.
NeuroImage 1997;5(3):229-39.
1997: Philip Seeman; Shitij Kapur
Clozapine occupies high levels of dopamine D2 receptors.
Life sciences 1997;60(12):PL 207-16.
1997: Roberto Cabeza; Cheryl L Grady; L Nyberg; Anthony R McIntosh; Endel Tulving; Shitij Kapur; JM Jennings; Sylvain Houle; Fergus I M Craik
Age-related differences in neural activity during memory encoding and retrieval: a positron emission tomography study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(1):391-400.
1996: Shitij Kapur; Robert B Zipursky; C Jones; Gary Remington; Alan Wilson; Jean N DaSilva; Sylvain Houle
The D2 receptor occupancy profile of loxapine determined using PET.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(6):562-6.
1996: Shitij Kapur; Endel Tulving; Roberto Cabeza; Anthony R McIntosh; S Houle; Fergus I M Craik
The neural correlates of intentional learning of verbal materials: a PET study in humans.
Brain research. Cognitive brain research 1996;4(4):243-9.
1996: Shitij Kapur; Gary Remington; C Jones; A Wilson; Jean N DaSilva; Sylvain Houle; Robert B Zipursky
High levels of dopamine D2 receptor occupancy with low-dose haloperidol treatment: a PET study.
The American journal of psychiatry 1996;153(7):948-50.
1996: Shitij Kapur; Gary Remington
Serotonin-dopamine interaction and its relevance to schizophrenia.
The American journal of psychiatry 1996;153(4):466-76.
1996: Jeffrey H Meyer; Shitij Kapur; Alan Wilson; Jean N DaSilva; Sylvain Houle; Gregory Brown
Neuromodulation of frontal and temporal cortex by intravenous d-fenfluramine: an [15O]H2O PET study in humans.
Neuroscience letters 1996;207(1):25-8.
1996: Shitij Kapur
5-HT2 antagonism and EPS benefits: is there a causal connection?
Psychopharmacology 1996;124(1-2):35-9.
1996: A Al-Jeshi; J J Jeffries; Shitij Kapur
Loxapine: an enigma.
Canadian journal of psychiatry. Revue canadienne de psychiatrie 1996;41(2):131-2.
1996: Michael Gemar; Shitij Kapur; Z V Segal; Gregory Brown; S Houle
Effects of self-generated sad mood on regional cerebral activity: a PET study in normal subjects.
Depression 1996;4(2):81-8.
1995: L Nyberg; Endel Tulving; R Habib; L G Nilsson; Shitij Kapur; Sylvain Houle; Roberto Cabeza; Anthony R McIntosh
Functional brain maps of retrieval mode and recovery of episodic information.
Neuroreport 1995;7(1):249-52.
1995: Shitij Kapur; Fergus I M Craik; C Jones; Gregory Brown; Sylvain Houle; Endel Tulving
Functional role of the prefrontal cortex in retrieval of memories: a PET study.
Neuroreport 1995;6(14):1880-4.
1995: Shitij Kapur; D Hussey; D Wilson; Sylvain Houle
The statistical power of [15O]-water PET activation studies of cognitive processes.
Nuclear medicine communications 1995;16(9):779-84.
1995: Shitij Kapur; Gary Remington; Robert B Zipursky; Alan Wilson; Sylvain Houle
The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: a PET study.
Life sciences 1995;57(10):PL103-7.
1994: Endel Tulving; H J Markowitsch; Shitij Kapur; R Habib; Sylvain Houle
Novelty encoding networks in the human brain: positron emission tomography data.
Neuroreport 1994;5(18):2525-8.
1994: Sylvain Houle; Shitij Kapur; R Rose; D Hussey; D Wilson
Absence of residual effects after physiological stimulation of the visual and motor cortex: an [15O]-H2O PET study in humans.
Nuclear medicine communications 1994;15(11):860-4.
1994: Shitij Kapur; R Rose; P F Liddle; R B Zipursky; Gregory Brown; Donald T Stuss; S Houle; E Tulving
The role of the left prefrontal cortex in verbal processing: semantic processing or willed action?
Neuroreport 1994;5(16):2193-6.
1994: Shitij Kapur; J Meyer; Alan Wilson; Sylvain Houle; Gregory Brown
Activation of specific cortical regions by apomorphine: an [15O]H2O PET study in humans.
Neuroscience letters 1994;176(1):21-4.
1994: Shitij Kapur; J Meyer; Alan Wilson; Sylvain Houle; Gregory Brown
Modulation of cortical neuronal activity by a serotonergic agent: a PET study in humans.
Brain research 1994;646(2):292-4.
1994: Endel Tulving; Shitij Kapur; Fergus I M Craik; Morris Moscovitch; Sylvain Houle
Hemispheric encoding/retrieval asymmetry in episodic memory: positron emission tomography findings.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2016-20.
1994: Endel Tulving; Shitij Kapur; H J Markowitsch; Fergus I M Craik; R Habib; Sylvain Houle
Neuroanatomical correlates of retrieval in episodic memory: auditory sentence recognition.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2012-5.
1994: Shitij Kapur; Fergus I M Craik; Endel Tulving; A A Wilson; Sylvain Houle; Gregory Brown
Neuroanatomical correlates of encoding in episodic memory: levels of processing effect.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2008-11.
1991: Matcheri S Keshavan; Shitij Kapur; J W Pettegrew
Magnetic resonance spectroscopy in psychiatry: potential, pitfalls, and promise.
The American journal of psychiatry 1991;148(8):976-85.