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Siddhartha Kar

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TOP 3
Siddhartha Kar; Meifang Wang; Brian I Carr
2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis.
Silvia D Stan; Siddhartha Kar; Gary D Stoner; Shivendra V Singh
Bioactive food components and cancer risk reduction.
Siddhartha Kar; Meifang Wang; Brian I Carr
alpha-Thrombin inhibits DNA synthesis in rat hepatocytes but not in hepatoma cells by receptor activation and proteolysis.

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All Publications

2008: Siddhartha Kar; Meifang Wang; Brian I Carr
2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis.
Cancer chemotherapy and pharmacology 2008;62(5):831-40.
2008: Silvia D Stan; Siddhartha Kar; Gary D Stoner; Shivendra V Singh
Bioactive food components and cancer risk reduction.
Journal of cellular biochemistry 2008;104(1):339-56.
2007: Siddhartha Kar; Meifang Wang; Brian I Carr
alpha-Thrombin inhibits DNA synthesis in rat hepatocytes but not in hepatoma cells by receptor activation and proteolysis.
Molecular and cellular biochemistry 2007;304(1-2):189-97.
2007: Brian I Carr; Siddhartha Kar; Meifang Wang; Ziqiu Wang
Growth inhibitory actions of prothrombin on normal hepatocytes: influence of matrix.
Cell biology international 2007;31(9):929-38.
2006: Siddhartha Kar; Meifang Wang; Seung Wook Ham; Brian I Carr
Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK.
Biochemical pharmacology 2006;72(10):1217-27.
2006: Siddhartha Kar; Meifang Wang; Seung Wook Ham; Brian I Carr
H32, a non-quinone sulfone analog of vitamin K3, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating ERK.
Cancer biology & therapy 2006;5(10):1340-7.
2006: Siddhartha Kar; Meifang Wang; Wei Yao; Christopher J Michejda; Brian I Carr
PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo.
Molecular cancer therapeutics 2006;5(6):1511-9.
2005: Vincent Peyregne; Siddhartha Kar; Seung Wook Ham; Meifang Wang; Ziqiu Wang; Brian I Carr
Novel hydroxyl naphthoquinones with potent Cdc25 antagonizing and growth inhibitory properties.
Molecular cancer therapeutics 2005;4(4):595-602.
2004: Siddhartha Kar; Meifang Wang; Kathryn S Rosi; Craig S Wilcox; Brian I Carr
Inhibition of rat liver regeneration after partial hepatectomy and induction of ERK phosphorylation by Cpd 5, a K vitamin-based anticancer compound.
Carcinogenesis 2004;25(12):2345-51.
2004: Lisheng Ge; Ziqiu Wang; Meifang Wang; Siddhartha Kar; Brian I Carr
Involvement of c-Myc in growth inhibition of Hep 3B human hepatoma cells by a vitamin K analog.
Journal of hepatology 2004;41(5):823-9.
2003: Zhenggang Ren; Siddhartha Kar; Ziqiu Wang; Meifang Wang; Joseph E Saavedra; Brian I Carr
JS-K, a novel non-ionic diazeniumdiolate derivative, inhibits Hep 3B hepatoma cell growth and induces c-Jun phosphorylation via multiple MAP kinase pathways.
Journal of cellular physiology 2003;197(3):426-34.
2003: Siddhartha Kar; Iliya Lefterov; Meifang Wang; John Lazo; Colleen N Scott; Craig S Wilcox; Brian I Carr
Binding and inhibition of Cdc25 phosphatases by vitamin K analogues.
Biochemistry 2003;42(35):10490-7.
2003: Siddhartha Kar; Meifang Wang; Craig S Wilcox; Brian I Carr
Antitumor and anticarcinogenic actions of Cpd 5: a new class of protein phosphatase inhibitor.
Carcinogenesis 2003;24(3):411-6.
2003: Brian I Carr; Ziqiu Wang; Meifang Wang; Siddhartha Kar; Craig S Wilcox; Kathryn S Rosi; Eileen C Southwick; John Lazo
A Cdc25A antagonizing K vitamin inhibits hepatocyte DNA synthesis in vitro and in vivo.
Journal of molecular biology 2003;326(3):721-35.
2002: Brian I Carr; Ziqiu Wang; Siddhartha Kar
K vitamins, PTP antagonism, and cell growth arrest.
Journal of cellular physiology 2002;193(3):263-74.
2002: Takahito Adachi; Siddhartha Kar; Meifang Wang; Brian I Carr
Transient and sustained ERK phosphorylation and nuclear translocation in growth control.
Journal of cellular physiology 2002;192(2):151-9.
2002: Siddhartha Kar; Takahito Adachi; Brian I Carr
EGFR-independent activation of ERK1/2 mediates growth inhibition by a PTPase antagonizing K-vitamin analog.
Journal of cellular physiology 2002;190(3):356-64.
2001: Ziqiu Wang; Eileen C Southwick; Meifang Wang; Siddhartha Kar; Kathryn S Rosi; Craig S Wilcox; John Lazo; Brian I Carr
Involvement of Cdc25A phosphatase in Hep3B hepatoma cell growth inhibition induced by novel K vitamin analogs.
Cancer research 2001;61(19):7211-6.
2000: Siddhartha Kar; Brian I Carr
Growth inhibition and protein tyrosine phosphorylation in MCF 7 breast cancer cells by a novel K vitamin.
Journal of cellular physiology 2000;185(3):386-93.