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Ioannis Karakikes

Research Profile

Chemicals & Drugs

Anatomy

Physiology

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Gene Transfer Techniques

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Publications

TOP 3
Ioannis Karakikes; Bertrand N Mukete; Shihong Zhang; Antoine H Chaanine; Roger J Hajjar; Dongtak Jeong; Soojeong Kang; Djamel Lebeche
Therapeutic cardiac-targeted delivery of miR-1 reverses pressure overload-induced cardiac hypertrophy and attenuates pathological remodeling.
Kenneth M Fish; Lahouaria Hadri; Kiyotake Ishikawa; Dongtak Jeong; Ioannis Karakikes; Yoshiaki Kawase; Evangelia G Kranias; Dennis Ladage; Hung Ly; Jochen Muller-Ehmsen; R Jude Samulski; Lisa Tilemann; Roger J Hajjar
AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling.
Ioannis Karakikes; Metodi V Metodiev; Gergana Metodieva; Jose M Miranda-Sayago; Ian E G Morrison; Cristina V Navarrete; Peter O'Toole; Richard J Cherry; Jesus Gomez; Nelson Fernandez
Interaction of HLA-DR and CD74 at the cell surface of antigen-presenting cells by single particle image analysis.

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All Publications

2013: Ioannis Karakikes; Bertrand N Mukete; Shihong Zhang; Antoine H Chaanine; Roger J Hajjar; Dongtak Jeong; Soojeong Kang; Djamel Lebeche
Therapeutic cardiac-targeted delivery of miR-1 reverses pressure overload-induced cardiac hypertrophy and attenuates pathological remodeling.
Journal of the American Heart Association 2013;2(2):e000078.
2013: Kenneth M Fish; Lahouaria Hadri; Kiyotake Ishikawa; Dongtak Jeong; Ioannis Karakikes; Yoshiaki Kawase; Evangelia G Kranias; Dennis Ladage; Hung Ly; Jochen Muller-Ehmsen; R Jude Samulski; Lisa Tilemann; Roger J Hajjar
AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling.
Circulation. Heart failure 2013;6(2):310-7.
2012: Ioannis Karakikes; Metodi V Metodiev; Gergana Metodieva; Jose M Miranda-Sayago; Ian E G Morrison; Cristina V Navarrete; Peter O'Toole; Richard J Cherry; Jesus Gomez; Nelson Fernandez
Interaction of HLA-DR and CD74 at the cell surface of antigen-presenting cells by single particle image analysis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(12):4886-96.
2012: Ioannis Karakikes; Yoshiaki Kawase; Dennis Ladage; Charlotte Morel; Kleopatra Rapti; Lisa Tilemann; Thomas Weber; Geng-Hua Yi; Krisztina Maria Zsebo; Judith K Gwathmey; Lahouaria Hadri; Kiyotake Ishikawa; Roger J Hajjar
Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(3):565-71.
2011: Dennis Ladage; C Morel; J Müller-Ehmsen; K Rapti; Yoshiaki Takewa; I C Turnbull; Kevin D Costa; Lahouaria Hadri; Roger J Hajjar; K Ishikawa; Ioannis Karakikes; Y Kawase
Delivery of gelfoam-enabled cells and vectors into the pericardial space using a percutaneous approach in a porcine model.
Gene therapy 2011;18(10):979-85.
2011: Perundurai S Dhandapany; Frank Fabris; Rahul Tonk; Ardo Illaste; Ioannis Karakikes; Mehran Sorourian; Jipo Sheng; Roger J Hajjar; Marco Tartaglia; Eric Sobie; Djamel Lebeche; Bruce D Gelb
Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes.
Journal of molecular and cellular cardiology 2011;51(1):4-15.
2011: Jagat C Borah; Shiraz Mujtaba; Ioannis Karakikes; Lei Zeng; Michaela Muller; Jigneshkumar Patel; Natasha Moshkina; Keita Morohashi; Weijia Zhang; Guillermo Gerona-Navarro; Roger J Hajjar; Ming-Ming Zhou
A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes.
Chemistry & biology 2011;18(4):531-41.
2011: Regis Bobe; Lahouaria Hadri; Jose J Lopez; Yassine Sassi; Fabrice Atassi; Ioannis Karakikes; Lifan Liang; Isabelle Limon; Anne-Marie Lompré; Stephane N Hatem; Roger J Hajjar; Larissa Lipskaia
SERCA2a controls the mode of agonist-induced intracellular Ca2+ signal, transcription factor NFAT and proliferation in human vascular smooth muscle cells.
Journal of molecular and cellular cardiology 2011;50(4):621-33.
2010: Ronen Beeri; Miguel Chaput; J Luis Guerrero; Yoshiaki Kawase; Chaim Yosefy; Suzan Abedat; Ioannis Karakikes; Charlotte Morel; Ashley Tisosky; Suzanne Sullivan; Mark D Handschumacher; Dan GILON; Gus J Vlahakes; Roger J Hajjar; Robert A Levine
Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation.
Circulation. Heart failure 2010;3(5):627-34.
2010: Hongwei Jin; Lahouaria Hadri; Julieta Palomeque; Charlotte Morel; Ioannis Karakikes; Roger Kaprielian; Roger J Hajjar; Djamel Lebeche
KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling.
Journal of molecular and cellular cardiology 2010;48(6):1169-79.
2010: Elisa Galende; Ioannis Karakikes; Lisa Edelmann; Robert J Desnick; Thomas Kerenyi; Georges Khoueiry; James Lafferty; Joseph T McGinn; Michael Brodman; Valentin Fuster; Roger J Hajjar; Katalin Polgar
Amniotic fluid cells are more efficiently reprogrammed to pluripotency than adult cells.
Cellular reprogramming 2010;12(2):117-25.
2009: Yoshiaki Takewa; Elie R Chemaly; Miyako Takaki; Li Fan Liang; Hongwei Jin; Ioannis Karakikes; Charlotte Morel; Yoshiyuki Taenaka; Eisuke Tatsumi; Roger J Hajjar
Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats.
American journal of physiology. Heart and circulatory physiology 2009;296(4):H1117-24.
2009: Ioannis Karakikes; Maengjo Kim; Lahouaria Hadri; Susumu Sakata; Yezhou Sun; Weijia Zhang; Elie R Chemaly; Roger J Hajjar; Djamel Lebeche
Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a.
PloS one 2009;4(7):e6474.
2007: Georgina M Ellison; Daniele Torella; Ioannis Karakikes; Saranya Purushothaman; Antonio Curcio; Cosimo Gasparri; Ciro Indolfi; N Tim Cable; David F Goldspink; Bernardo Nadal-Ginard
Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells.
The Journal of biological chemistry 2007;282(15):11397-409.
2007: Daniele Torella; Georgina M Ellison; Ioannis Karakikes; Bernardo Nadal-Ginard
Resident cardiac stem cells.
Cellular and molecular life sciences : CMLS 2007;64(6):661-73.
2007: Georgina M Ellison; Daniele Torella; Ioannis Karakikes; Bernardo Nadal-Ginard
Myocyte death and renewal: modern concepts of cardiac cellular homeostasis.
Nature clinical practice. Cardiovascular medicine 2007;4 Suppl 1():S52-9.
2007: Daniele Torella; Georgina M Ellison; Ioannis Karakikes; Bernardo Nadal-Ginard
Growth-factor-mediated cardiac stem cell activation in myocardial regeneration.
Nature clinical practice. Cardiovascular medicine 2007;4 Suppl 1():S46-51.
2003: Ian E G Morrison; Ioannis Karakikes; Rosamund E Barber; Nelson Fernández; Richard J Cherry
Detecting and quantifying colocalization of cell surface molecules by single particle fluorescence imaging.
Biophysical journal 2003;85(6):4110-21.
2003: Ioannis Karakikes; Rosamund E Barber; Ian E G Morrison; Nelson Fernández; Richard J Cherry
Co-localization of cell surface receptors at high spatial resolution by single-particle fluorescence imaging.
Biochemical Society transactions 2003;31(Pt 6):1453-5.
2003: Richard J Cherry; Ian E G Morrison; Ioannis Karakikes; Rosamund E Barber; Gary Silkstone; Nelson Fernández
Measurements of associations of cell-surface receptors by single-particle fluorescence imaging.
Biochemical Society transactions 2003;31(Pt 5):1028-31.