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Dimitris Kardassis

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Philippe Costet; Ewa Ehrenborg; Barbara Fielding; Rachel Fisher; Albert Groen; Anne Tybjaerg Hansen; Dimitris Kardassis; Ernst Malle; Monique Mulder; Andreas Niemeier; Giuseppe D Norata; Arnold von Eckardstein
European lipoprotein club: report of the 35th ELC annual conference (Tutzing, 10th-13th September 2012).
Adelina Duka; Panagiotis Fotakis; Dimitra Georgiadou; Dimitris Kardassis; Andreas Kateifides; efstratios stratikos; Kalliopi Tzavlaki; Leonard von Eckardstein; Vassilis I Zannis
ApoA-IV promotes the biogenesis of apoA-IV-containing HDL particles with the participation of ABCA1 and LCAT.
Dimitris Kardassis; Max Petzold; Marie Schönander; Lars Sjöström; Odd Bech-Hanssen; Kristjan Karason
Impact of body composition, fat distribution and sustained weight loss on cardiac function in obesity.

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2013: Philippe Costet; Ewa Ehrenborg; Barbara Fielding; Rachel Fisher; Albert Groen; Anne Tybjaerg Hansen; Dimitris Kardassis; Ernst Malle; Monique Mulder; Andreas Niemeier; Giuseppe D Norata; Arnold von Eckardstein
European lipoprotein club: report of the 35th ELC annual conference (Tutzing, 10th-13th September 2012).
Atherosclerosis 2013;226(2):510-6.
2013: Adelina Duka; Panagiotis Fotakis; Dimitra Georgiadou; Dimitris Kardassis; Andreas Kateifides; efstratios stratikos; Kalliopi Tzavlaki; Leonard von Eckardstein; Vassilis I Zannis
ApoA-IV promotes the biogenesis of apoA-IV-containing HDL particles with the participation of ABCA1 and LCAT.
Journal of lipid research 2013;54(1):107-15.
2012: Dimitris Kardassis; Max Petzold; Marie Schönander; Lars Sjöström; Odd Bech-Hanssen; Kristjan Karason
Impact of body composition, fat distribution and sustained weight loss on cardiac function in obesity.
International journal of cardiology 2012;159(2):128-33.
2012: Beata Wojciak-Stothard; Yixing Wu; Lan Zhao; Louise S Harrington; Olivier Dubois; Minzhou Huang; Dimitris Kardassis; Harrington Louise; Jane A Mitchell; Eduardo Oliver; George C Prendergast; Eleftheria Vasilaki; Martin R Wilkins
Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia.
Circulation research 2012;110(11):1423-34.
2012: Dimitris Kardassis; Marie Schönander; Lars Sjöström; Odd Bech-Hanssen; Kristjan Karason
The influence of body composition, fat distribution, and sustained weight loss on left ventricular mass and geometry in obesity.
Obesity (Silver Spring, Md.) 2012;20(3):605-11.
2012: Jesper Schou; Efstathia Thymiakou; Ruth Frikke-Schmidt; Peer Grande; Gorm Jensen; Dimitris Kardassis; Børge G Nordestgaard; Anne Tybjaerg-Hansen
Genetic variation in ABCG1 and risk of myocardial infarction and ischemic heart disease.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(2):506-15.
2012: Violeta G Trusca; Dimitris Kardassis; Irina C Florea; Anca Gafencu
STAT1 interacts with RXRα to upregulate ApoCII gene expression in macrophages.
PloS one 2012;7(7):e40463.
2011: Vassilios M Vazgiourakis; Sule Yavuz; Neslihan Yilmaz; Maria Zervou; George Bertsias; Dimitrios T Boumpas; Christianna Choulaki; Dimitris Kardassis; Maria Melissourgaki; Darren Plant; Prodromos Sidiropoulos; Rene E Toes; Leendert A Trouw; George N Goulielmos
A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis.
Annals of the rheumatic diseases 2011;70(12):2184-90.
2011: Stefan Stender; Aristomenis Anestis; Ruth Frikke-Schmidt; Dimitris Kardassis; Børge G Nordestgaard; Amar A Sethi; Anne Tybjaerg-Hansen
Genetic variation in liver X receptor alpha and risk of ischemic vascular disease in the general population.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(12):2990-6.
2011: Andreas K Kateifides; Angeliki Chroni; Adelina Duka; Irina N Gorshkova; Dimitris Kardassis; Vassilis I Zannis
Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL.
Journal of lipid research 2011;52(7):1363-72.
2011: Ioanna Mosialou; Konstantin Krasagakis; Dimitris Kardassis
Opposite regulation of the human apolipoprotein M gene by hepatocyte nuclear factor 1 and Jun transcription factors.
The Journal of biological chemistry 2011;286(19):17259-69.
2011: Violeta Georgeta Trusca; Elena Valeria Fuior; Irina Cristina Florea; Dimitris Kardassis; Maya Simionescu; Anca Violeta Gafencu
Macrophage-specific up-regulation of apolipoprotein E gene expression by STAT1 is achieved via long range genomic interactions.
The Journal of biological chemistry 2011;286(16):13891-904.
2011: Pascale M Ohnsorg; Lucia Rohrer; Damir Perisa; Andreas Kateifides; Angeliki Chroni; Dimitris Kardassis; Vassilis I Zannis; Arnold von Eckardstein
Carboxyl terminus of apolipoprotein A-I (ApoA-I) is necessary for the transport of lipid-free ApoA-I but not prelipidated ApoA-I particles through aortic endothelial cells.
The Journal of biological chemistry 2011;286(10):7744-54.
2011: Elsa Papadimitriou; Dimitris Kardassis; Aristidis Moustakas; Christos Stournaras
TGFβ-induced early activation of the small GTPase RhoA is Smad2/3-independent and involves Src and the guanine nucleotide exchange factor Vav2.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2011;28(2):229-38.
2010: Ioanna Mosialou; Vassilis I Zannis; Dimitris Kardassis
Regulation of human apolipoprotein m gene expression by orphan and ligand-dependent nuclear receptors.
The Journal of biological chemistry 2010;285(40):30719-30.
2010: Sofia Mavridou; Maria Venihaki; Olga Rassouli; Christos Tsatsanis; Dimitris Kardassis
Feedback inhibition of human scavenger receptor class B type I gene expression by glucocorticoid in adrenal and ovarian cells.
Endocrinology 2010;151(7):3214-24.
2010: Twee Tsao; Steven M Kornblau; Stephen Safe; Julie C Watt; Vivian Ruvolo; Wenjing Chen; Yihua Qiu; Kevin R Coombes; Zhenlin Ju; Maen Abdelrahim; Wendy D Schober; Xiaoyang Ling; Dimitris Kardassis; Colin Meyer; Aaron D Schimmer; Andrew Lamb; Michael Andreeff; Marina Konopleva
Role of peroxisome proliferator-activated receptor-gamma and its coactivator DRIP205 in cellular responses to CDDO (RTA-401) in acute myelogenous leukemia.
Cancer research 2010;70(12):4949-60.
2010: Eleftheria Vasilaki; Elsa Papadimitriou; Virginia Tajadura; Anne J Ridley; Christos Stournaras; Dimitris Kardassis
Transcriptional regulation of the small GTPase RhoB gene by TGF{beta}-induced signaling pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(3):891-905.
2009: Eleftheria Vasilaki; Manos Siderakis; Paraskevi Papakosta; Konstantina Skourti-Stathaki; Sofia Mavridou; Dimitris Kardassis
Novel regulation of Smad3 oligomerization and DNA binding by its linker domain.
Biochemistry 2009;48(35):8366-78.
2009: Dimitris Kardassis; Carol Murphy; Theodore Fotsis; Aristidis Moustakas; Christos Stournaras
Control of transforming growth factor beta signal transduction by small GTPases.
The FEBS journal 2009;276(11):2947-65.
2009: Tonia Akoumianaki; Dimitris Kardassis; Hara Polioudaki; Spyros D Georgatos; Panayiotis A Theodoropoulos
Nucleocytoplasmic shuttling of soluble tubulin in mammalian cells.
Journal of cell science 2009;122(Pt 8):1111-8.
2009: Bente Grüner Sveälv; Asa Cider; Margareta Scharin Täng; Eva Angwald; Dimitris Kardassis; Bert Andersson
Benefit of warm water immersion on biventricular function in patients with chronic heart failure.
Cardiovascular ultrasound 2009;7():33.
2009: George Bertsias; Magda Nakou; Christianna Choulaki; Amalia Raptopoulou; Eva D Papadimitraki; George N Goulielmos; Heraklis D Kritikos; Prodromos Sidiropoulos; Maria Tzardi; Dimitris Kardassis; Clio Mamalaki; Dimitrios T Boumpas
Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus.
Arthritis and rheumatism 2009;60(1):207-18.
2008: Aristides Moschonas; Maria Kouraki; Pauline G Knox; Efstathia Thymiakou; Dimitris Kardassis; Aristides G Eliopoulos
CD40 induces antigen transporter and immunoproteasome gene expression in carcinomas via the coordinated action of NF-kappaB and of NF-kappaB-mediated de novo synthesis of IRF-1.
Molecular and cellular biology 2008;28(20):6208-22.
2008: Lina Vardouli; Eleftheria Vasilaki; Elsa Papadimitriou; Dimitris Kardassis; Christos Stournaras
A novel mechanism of TGFbeta-induced actin reorganization mediated by Smad proteins and Rho GTPases.
The FEBS journal 2008;275(16):4074-87.
2008: Melanthia Stavroulaki; Dimitris Kardassis; Ekaterini Chatzaki; George Sakellaris; Carsten Lindschau; Hermann Haller; Androniki Tosca; Konstantin Krasagakis
Exposure of normal human melanocytes to a tumor promoting phorbol ester reverses growth suppression by transforming growth factor beta.
Journal of cellular physiology 2008;214(2):363-70.
2008: Parviz Minoo; Lingyan Hu; Nian-Ling Zhu; Zea Borok; Saverio Bellusci; John Groffen; Dimitris Kardassis; Changgong Li
SMAD3 prevents binding of NKX2.1 and FOXA1 to the SpB promoter through its MH1 and MH2 domains.
Nucleic acids research 2008;36(1):179-88.
2007: Vassiliki Prokova; Sofia Mavridou; Paraskevi Papakosta; Kyriacos Petratos; Dimitris Kardassis
Novel mutations in Smad proteins that inhibit signaling by the transforming growth factor beta in mammalian cells.
Biochemistry 2007;46(48):13775-86.
2007: Efstathia Thymiakou; Vassilis I Zannis; Dimitris Kardassis
Physical and functional interactions between liver X receptor/retinoid X receptor and Sp1 modulate the transcriptional induction of the human ATP binding cassette transporter A1 gene by oxysterols and retinoids.
Biochemistry 2007;46(41):11473-83.
2007: Kassi Psifogeorgou; Paraskevi Papakosta; Scott J Russo; Rachael L Neve; Dimitris Kardassis; Stephen J Gold; Venetia Zachariou
RGS9-2 is a negative modulator of mu-opioid receptor function.
Journal of neurochemistry 2007;103(2):617-25.
2007: Georgios Koukos; Angeliki Chroni; Adelina Duka; Dimitris Kardassis; Vassilis I Zannis
LCAT can rescue the abnormal phenotype produced by the natural ApoA-I mutations (Leu141Arg)Pisa and (Leu159Arg)FIN.
Biochemistry 2007;46(37):10713-21.
2007: Georgios Koukos; Angeliki Chroni; Adelina Duka; Dimitris Kardassis; Vassilis I Zannis
Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with LCAT.
The Biochemical journal 2007;406(1):167-74.
2007: Anca Gafencu; Marius R Robciuc; Elena Fuior; Vassilis I Zannis; Dimitris Kardassis; Maya Simionescu
Inflammatory signaling pathways regulating ApoE gene expression in macrophages.
The Journal of biological chemistry 2007;282(30):21776-85.
2007: Konstantinos Drosatos; Despina Sanoudou; Kyriakos E Kypreos; Dimitris Kardassis; Vassilis I Zannis
A dominant negative form of the transcription factor c-Jun affects genes that have opposing effects on lipid homeostasis in mice.
The Journal of biological chemistry 2007;282(27):19556-64.
2006: Varvara Nikolaidou-Neokosmidou; Vassilis I Zannis; Dimitris Kardassis
Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor kappaB pathway.
The Biochemical journal 2006;398(3):439-50.
2005: George Koutsodontis; Eleftheria Vasilaki; Wan-Chih Chou; Paraskevi Papakosta; Dimitris Kardassis
Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: importance for the regulation of genes involved in cell-cycle arrest and apoptosis.
The Biochemical journal 2005;389(Pt 2):443-55.
2005: Vassiliki Prokova; Sofia Mavridou; Paraskevi Papakosta; Dimitris Kardassis
Characterization of a novel transcriptionally active domain in the transforming growth factor beta-regulated Smad3 protein.
Nucleic acids research 2005;33(12):3708-21.
2004: George Koutsodontis; Dimitris Kardassis
Inhibition of p53-mediated transcriptional responses by mithramycin A.
Oncogene 2004;23(57):9190-200.
2004: Vassilis I Zannis; Angeliki Chroni; Kyriakos E Kypreos; Horng-Yuan Kan; Thais Borges Cesar; Eleni E Zanni; Dimitris Kardassis
Probing the pathways of chylomicron and HDL metabolism using adenovirus-mediated gene transfer.
Current opinion in lipidology 2004;15(2):151-66.
2003: Eudoxia G Hatzivassiliou; Georgios Koukos; Agnes Ribeiro; Vassilis I Zannis; Dimitris Kardassis
Functional specificity of two hormone response elements present on the human apoA-II promoter that bind retinoid X receptor alpha/thyroid receptor beta heterodimers for retinoids and thyroids: synergistic interactions between thyroid receptor beta and upstream stimulatory factor 2a.
The Biochemical journal 2003;376(Pt 2):423-31.
2003: Dimitris Kardassis; Anastasia Roussou; Paraskevi Papakosta; Konstantinos Boulias; Iannis Talianidis; Vassilis I Zannis
Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoids.
The Biochemical journal 2003;372(Pt 2):291-304.
2003: Vassilis I Zannis; Tong Liu; Markella Zanni; Horng-Yuan Kan; Dimitris Kardassis
Regulatory gene mutations affecting apolipoprotein gene expression: functions and regulatory behavior of known genes may guide future pharmacogenomic approaches to therapy.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003;41(4):411-24.
2003: Wan-Chih Chou; Vassiliki Prokova; Keiko Shiraishi; Ulrich Valcourt; Aristidis Moustakas; Margarita Hadzopoulou-Cladaras; Vassilis I Zannis; Dimitris Kardassis
Mechanism of a transcriptional cross talk between transforming growth factor-beta-regulated Smad3 and Smad4 proteins and orphan nuclear receptor hepatocyte nuclear factor-4.
Molecular biology of the cell 2003;14(3):1279-94.
2002: George Koutsodontis; Aristidis Moustakas; Dimitris Kardassis
The role of Sp1 family members, the proximal GC-rich motifs, and the upstream enhancer region in the regulation of the human cell cycle inhibitor p21WAF-1/Cip1 gene promoter.
Biochemistry 2002;41(42):12771-84.
2002: Vassiliki Prokova; George Mosialos; Dimitris Kardassis
Inhibition of transforming growth factor beta signaling and Smad-dependent activation of transcription by the Latent Membrane Protein 1 of Epstein-Barr virus.
The Journal of biological chemistry 2002;277(11):9342-50.
2002: Dimitris Kardassis; Eileen Falvey; Panayota Tsantili; Margarita Hadzopoulou-Cladaras; Vassilis I Zannis
Direct physical interactions between HNF-4 and Sp1 mediate synergistic transactivation of the apolipoprotein CIII promoter.
Biochemistry 2002;41(4):1217-28.
2001: George Koutsodontis; I Tentes; Paraskevi Papakosta; Aristidis Moustakas; Dimitris Kardassis
Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.
The Journal of biological chemistry 2001;276(31):29116-25.
2001: Vassilis I Zannis; Horng-Yuan Kan; A Kritis; Eleni E Zanni; Dimitris Kardassis
Transcriptional regulatory mechanisms of the human apolipoprotein genes in vitro and in vivo.
Current opinion in lipidology 2001;12(2):181-207.
2001: Vassilis I Zannis; Horng-Yuan Kan; A Kritis; Eleni E Zanni; Dimitris Kardassis
Transcriptional regulation of the human apolipoprotein genes.
Frontiers in bioscience : a journal and virtual library 2001;6():D456-504.
2000: Dimitris Kardassis; Katerina Pardali; Vassilis I Zannis
SMAD proteins transactivate the human ApoCIII promoter by interacting physically and functionally with hepatocyte nuclear factor 4.
The Journal of biological chemistry 2000;275(52):41405-14.
2000: Katerina Pardali; Akira Kurisaki; Anita Morén; Peter ten Dijke; Dimitris Kardassis; Aristidis Moustakas
Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.
The Journal of biological chemistry 2000;275(38):29244-56.
1999: Dimitris Kardassis; Paraskevi Papakosta; Katerina Pardali; Aristidis Moustakas
c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1.
The Journal of biological chemistry 1999;274(41):29572-81.
1999: Anna Tsapara; Dimitris Kardassis; Aristidis Moustakas; Achille Gravanis; Christos Stournaras
Expression and characterization of Cys374 mutated human beta-actin in two different mammalian cell lines: impaired microfilament organization and stability.
FEBS letters 1999;455(1-2):117-22.
1999: Sophia Lavrentiadou; Margarita Hadzopoulou-Cladaras; Dimitris Kardassis; Vassilis I Zannis
Binding specificity and modulation of the human ApoCIII promoter activity by heterodimers of ligand-dependent nuclear receptors.
Biochemistry 1999;38(3):964-75.
1998: Margarita Hadzopoulou-Cladaras; Sophia Lavrentiadou; Vassilis I Zannis; Dimitris Kardassis
Transactivation of the ApoCIII promoter by ATF-2 and repression by members of the Jun family.
Biochemistry 1998;37(40):14078-87.
1998: Dimitris Kardassis; E Sacharidou; Vassilis I Zannis
Transactivation of the human apolipoprotein CII promoter by orphan and ligand-dependent nuclear receptors. The regulatory element CIIC is a thyroid hormone response element.
The Journal of biological chemistry 1998;273(28):17810-6.
1998: Aristidis Moustakas; Dimitris Kardassis
Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6733-8.
1998: Pelagia Vorgia; Vassilis I Zannis; Dimitris Kardassis
A short proximal promoter and the distal hepatic control region-1 (HCR-1) contribute to the liver specificity of the human apolipoprotein C-II gene. Hepatic enhancement by HCR-1 requires two proximal hormone response elements which have different binding specificities for orphan receptors HNF-4, ARP-1, and EAR-2.
The Journal of biological chemistry 1998;273(7):4188-96.
1997: Dimitris Kardassis; I Tzameli; Margarita Hadzopoulou-Cladaras; Iannis Talianidis; Vassilis I Zannis
Distal apolipoprotein C-III regulatory elements F to J act as a general modular enhancer for proximal promoters that contain hormone response elements. Synergism between hepatic nuclear factor-4 molecules bound to the proximal promoter and distal enhancer sites.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(1):222-32.
1996: Dimitris Kardassis; M Laccotripe; Iannis Talianidis; Vassilis I Zannis
Transcriptional regulation of the genes involved in lipoprotein transport. The role of proximal promoters and long-range regulatory elements and factors in apolipoprotein gene regulation.
Hypertension 1996;27(4):980-1008.
1993: Philippe Cardot; Jean CHAMBAZ; Dimitris Kardassis; C Cladaras; Vassilis I Zannis
Factors participating in the liver-specific expression of the human apolipoprotein A-II gene and their significance for transcription.
Biochemistry 1993;32(35):9080-93.
1993: Vassilis I Zannis; Dimitris Kardassis; E E Zanni
Genetic mutations affecting human lipoproteins, their receptors, and their enzymes.
Advances in human genetics 1993;21():145-319.
1992: John A A Ladias; Margarita Hadzopoulou-Cladaras; Dimitris Kardassis; Philippe Cardot; J Cheng; Vassilis I Zannis; C Cladaras
Transcriptional regulation of human apolipoprotein genes ApoB, ApoCIII, and ApoAII by members of the steroid hormone receptor superfamily HNF-4, ARP-1, EAR-2, and EAR-3.
The Journal of biological chemistry 1992;267(22):15849-60.
1992: Dimitris Kardassis; Vassilis I Zannis; C Cladaras
Organization of the regulatory elements and nuclear activities participating in the transcription of the human apolipoprotein B gene.
The Journal of biological chemistry 1992;267(11):7956.
1992: Dimitris Kardassis; Vassilis I Zannis; C Cladaras
Organization of the regulatory elements and nuclear activities participating in the transcription of the human apolipoprotein B gene.
The Journal of biological chemistry 1992;267(4):2622-32.
1991: K Ogami; Dimitris Kardassis; C Cladaras; Vassilis I Zannis
Purification and characterization of a heat stable nuclear factor CIIIB1 involved in the regulation of the human ApoC-III gene.
The Journal of biological chemistry 1991;266(15):9640-6.
1991: Vassilis I Zannis; Dimitris Kardassis; K Ogami; Margarita Hadzopoulou-Cladaras; C Cladaras
Transcriptional regulation of the human apolipoprotein genes.
Advances in experimental medicine and biology 1991;285():1-23.
1990: Dimitris Kardassis; Vassilis I Zannis; C Cladaras
Purification and characterization of the nuclear factor BA1. A transcriptional activator of the human apoB gene.
The Journal of biological chemistry 1990;265(35):21733-40.
1990: Dimitris Kardassis; Margarita Hadzopoulou-Cladaras; D P Ramji; R Cortese; Vassilis I Zannis; C Cladaras
Characterization of the promoter elements required for hepatic and intestinal transcription of the human apoB gene: definition of the DNA-binding site of a tissue-specific transcriptional factor.
Molecular and cellular biology 1990;10(6):2653-9.
1988: Vassilis I Zannis; M M Hussain; Margarita Hadzopoulou-Cladaras; A Kouvatsi; Dimitris Kardassis; C Cladaras
Molecular biology of human apolipoprotein B and related diseases.
Advances in experimental medicine and biology 1988;243():107-21.