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Christian Kardinal

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Sheetal Ramachandran; Christian Kardinal; Sabine Klebba-Faerber; Doan Duy Hai Tran; Anthony D Whetton; Teruko Tamura
An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5.
Irini Tossidou; Marc Dangers; Alexandra Koch; Dominique T Brandt; Mario Schiffer; Christian Kardinal
Tyrosine phosphatase SHP-2 is a regulator of p27(Kip1) tyrosine phosphorylation.
Alexandra Koch; Michaela Scherr; B Breyer; Annalisa Mancini; Christian Kardinal; Karin Battmer; Matthias Eder; Teruko Tamura
Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr-Abl transformed cells via the alteration of signaling complex and the receptor turnover.

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All Publications

2011: Sheetal Ramachandran; Christian Kardinal; Sabine Klebba-Faerber; Doan Duy Hai Tran; Anthony D Whetton; Teruko Tamura
An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5.
RNA (New York, N.Y.) 2011;17(11):1957-66.
2008: Irini Tossidou; Marc Dangers; Alexandra Koch; Dominique T Brandt; Mario Schiffer; Christian Kardinal
Tyrosine phosphatase SHP-2 is a regulator of p27(Kip1) tyrosine phosphorylation.
Cell cycle (Georgetown, Tex.) 2008;7(24):3858-68.
2008: Alexandra Koch; Michaela Scherr; B Breyer; Annalisa Mancini; Christian Kardinal; Karin Battmer; Matthias Eder; Teruko Tamura
Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr-Abl transformed cells via the alteration of signaling complex and the receptor turnover.
Oncogene 2008;27(34):4678-89.
2007: Irini Tossidou; Christian Kardinal; Imke Peters; Wilhelm Kriz; Andrey Shaw; Ivan Dikic; Sergey Tkachuk; Inna Dumler; Hermann Haller; Mario Schiffer
CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes.
The Journal of biological chemistry 2007;282(10):7457-64.
2006: Melchior Lauten; André Schrauder; Christian Kardinal; Jochen Harbott; Karl Welte; Brigitte Schlegelberger; Martin Schrappe; Nils von neuhoff
Unsupervised proteome analysis of human leukaemia cells identifies the Valosin-containing protein as a putative marker for glucocorticoid resistance.
Leukemia 2006;20(5):820-6.
2006: Christian Kardinal; Marc Dangers; Angelika Kardinal; Alexandra Koch; Dominique Tobias Brandt; Teruko Tamura; Karl Welte
Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p27Kip1 in the acute promyelocytic leukemia cell line NB4.
Blood 2006;107(3):1133-40.
2004: Christina Ehrhardt; Christian Kardinal; Walter J Wurzer; Thorsten Wolff; Christoph von Eichel-Streiber; Stephan Pleschka; Oliver Planz; Stephan Ludwig
Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3.
FEBS letters 2004;567(2-3):230-8.
2003: Melchior Lauten; Carmela Beger; K Gerdes; Girmay Asgedom; Christian Kardinal; Karl Welte; Martin Schrappe
Expression of heat-shock protein 90 in glucocorticoid-sensitive and -resistant childhood acute lymphoblastic leukaemia.
Leukemia 2003;17(8):1551-6.
2002: Kristian Schweimer; Silke Hoffmann; Finn Bauer; Ute Friedrich; Christian Kardinal; Stephan M Feller; Brigitte Biesinger; Heinrich Sticht
Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck.
Biochemistry 2002;41(16):5120-30.
2001: Christian Kardinal; B Konkol; H Lin; M Eulitz; Enrico K Schmidt; Z Estrov; Moshe Talpaz; R B Arlinghaus; Stephan M Feller
Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes.
Blood 2001;98(6):1773-81.
2001: Marc Lewitzky; Christian Kardinal; N H Gehring; Enrico K Schmidt; B Konkol; M Eulitz; Walter Birchmeier; Ute Schaeper; Stephan M Feller
The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
Oncogene 2001;20(9):1052-62.
2000: Christian Kardinal; B Konkol; A Schulz; Guido Posern; H Lin; Knut Adermann; M Eulitz; Z Estrov; Moshe Talpaz; R B Arlinghaus; Stephan M Feller
Cell-penetrating SH3 domain blocker peptides inhibit proliferation of primary blast cells from CML patients.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(11):1529-38.
2000: Jan Voss; Guido Posern; JR Hannemann; LM Wiedemann; A G Turhan; Hélène A Poirel; Olivier A Bernard; Knut Adermann; Christian Kardinal; Stephan M Feller
The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways.
Oncogene 2000;19(13):1684-90.
1999: Jens-Christian Albrecht; Ute Friedrich; Christian Kardinal; J Koehn; Bernhard Fleckenstein; S M Feller; Brigitte Biesinger
Herpesvirus ateles gene product Tio interacts with nonreceptor protein tyrosine kinases.
Journal of virology 1999;73(6):4631-9.
1999: Christian Kardinal; Guido Posern; J Zheng; BS Knudsen; Ismail Moarefi; Stephan M Feller
Rational development of cell-penetrating high affinity SH3 domain binding peptides that selectively disrupt the signal transduction of Crk family adapters. Amgen Peptide Technology Group.
Annals of the New York Academy of Sciences 1999;886():289-92.
1998: Stephan M Feller; Guido Posern; Jan Voss; Christian Kardinal; D Sakkab; J Zheng; BS Knudsen
Physiological signals and oncogenesis mediated through Crk family adapter proteins.
Journal of cellular physiology 1998;177(4):535-52.
1998: W Oehrl; Christian Kardinal; S Ruf; Knut Adermann; J Groffen; G S Feng; J Blenis; Tse-Hua Tan; Stephan M Feller
The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins.
Oncogene 1998;17(15):1893-901.
1998: Guido Posern; J Zheng; BS Knudsen; Christian Kardinal; K B Müller; Jan Voss; T Shishido; David Cowburn; G Cheng; B Wang; Gary Kruh; S K Burrell; C A Jacobson; D M Lenz; TJ Zamborelli; Knut Adermann; H Hanafusa; Stephan M Feller
Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G.
Oncogene 1998;16(15):1903-12.