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Diana Karpman

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Lisa Sartz; Anne-lie Ståhl; Kerstin Westman; Veronique Fremeaux-Bacchi; Martin E Johansson; AnnCharlotte Kristoffersson; Kristina Nilsson-Ekdahl; Anders I Olin; Diana Karpman
A novel C3 mutation causing increased formation of the C3 convertase in familial atypical hemolytic uremic syndrome.
Tom Obrig; Diana Karpman
Shiga toxin pathogenesis: kidney complications and renal failure.
Zivile D Békássy; Carla Calderon Toledo; AnnCharlotte Kristoffersson; Gustav Leoj; Shana R Leopold; Maria-Thereza Perez; Diana Karpman
Intestinal damage in enterohemorrhagic Escherichia coli infection.

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All Publications

2012: Lisa Sartz; Anne-lie Ståhl; Kerstin Westman; Veronique Fremeaux-Bacchi; Martin E Johansson; AnnCharlotte Kristoffersson; Kristina Nilsson-Ekdahl; Anders I Olin; Diana Karpman
A novel C3 mutation causing increased formation of the C3 convertase in familial atypical hemolytic uremic syndrome.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(4):2030-7.
2012: Tom Obrig; Diana Karpman
Shiga toxin pathogenesis: kidney complications and renal failure.
Current topics in microbiology and immunology 2012;357():105-36.
2011: Zivile D Békássy; Carla Calderon Toledo; AnnCharlotte Kristoffersson; Gustav Leoj; Shana R Leopold; Maria-Thereza Perez; Diana Karpman
Intestinal damage in enterohemorrhagic Escherichia coli infection.
Pediatric nephrology (Berlin, Germany) 2011;26(11):2059-71.
2011: Damien Brackman; Veronique Frémeaux-Bacchi; Anna Bjerre; AnnCharlotte Kristoffersson; Sabine Leh; Lisa Sartz; Ramesh Tati; Diana Karpman
Thrombotic microangiopathy mimicking membranoproliferative glomerulonephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(10):3399-403.
2011: Robin Kahn; Diana Karpman
Kinin system activation in vasculitis.
Acta paediatrica (Oslo, Norway : 1992) 2011;100(7):950-7.
2011: Carla Calderon Toledo; Ida Arvidsson; Diana Karpman
Cross-reactive protection against enterohemorrhagic Escherichia coli infection by enteropathogenic E. coli in a mouse model.
Infection and immunity 2011;79(6):2224-33.
2011: Anne-lie Ståhl; Lisa Sartz; Diana Karpman
Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome.
Blood 2011;117(20):5503-13.
2011: Ramesh Tati; AnnCharlotte Kristoffersson; Minola Manea-Hedström; Peter Mathieson; Matthias Mörgelin; David Motto; Simon Satchell; Anne-Lie Ståhl; Diana Karpman
Phenotypic expression of ADAMTS13 in glomerular endothelial cells.
PloS one 2011;6(6):e21587.
2011: Roland Schmitt; Rafael T Krmar; AnnCharlotte Kristoffersson; Magnus Söderberg; Diana Karpman
IgA nephropathy associated with a novel N-terminal mutation in factor H.
European journal of pediatrics 2011;170(1):107-10.
2010: Diana Karpman; Lisa Sartz; Sally Johnson
Pathophysiology of typical hemolytic uremic syndrome.
Seminars in thrombosis and hemostasis 2010;36(6):575-85.
2010: Roland Schmitt; Fredric Carlsson; Matthias Mörgelin; Ramesh Tati; Gunnar Lindahl; Diana Karpman
Tissue deposits of IgA-binding streptococcal M proteins in IgA nephropathy and Henoch-Schonlein purpura.
The American journal of pathology 2010;176(2):608-18.
2010: Hans Fischer; Nataliya Lutay; Bryndís Ragnarsdóttir; Manisha Yadav; Klas Jönsson; Alexander Urbano; Ahmed Al Hadad; Sebastian Rämisch; Petter Storm; Ulrich Dobrindt; Ellaine Salvador; Diana Karpman; Ulf Jodal; Catharina Svanborg
Pathogen specific, IRF3-dependent signaling and innate resistance to human kidney infection.
PLoS pathogens 2010;6(9):e1001109.
2010: Bryndís Ragnarsdóttir; Klas Jönsson; Alexander Urbano; Jenny Grönberg-Hernandez; Nataliya Lutay; Martti Tammi; Mattias Gustafsson; Ann-Charlotte Lundstedt; Irene Leijonhufvud; Diana Karpman; Björn Wullt; Lennart Truedsson; Ulf Jodal; Björn Andersson; Catharina Svanborg
Toll-like receptor 4 promoter polymorphisms: common TLR4 variants may protect against severe urinary tract infection.
PloS one 2010;5(5):e10734.
2010: Minola Manea; Ramesh Tati; Jessica Karlsson; Zivile D Békássy; Diana Karpman
Biologically active ADAMTS13 is expressed in renal tubular epithelial cells.
Pediatric nephrology (Berlin, Germany) 2010;25(1):87-96.
2009: Anne-lie Ståhl; AnnCharlotte Kristoffersson; Anders I Olin; Martin L Olsson; Anne-Marie Roodhooft; Willem Proesmans; Diana Karpman
A novel mutation in the complement regulator clusterin in recurrent hemolytic uremic syndrome.
Molecular immunology 2009;46(11-12):2236-43.
2009: Robin Kahn; Thomas Hellmark; L M Fredrik Leeb-Lundberg; Nasrin Akbari; Mihail Todiras; Tor Olofsson; Jörgen Wieslander; Anders Christensson; Kerstin Westman; Michael Bader; Werner Müller-Esterl; Diana Karpman
Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7906-15.
2009: Diana Karpman; Robin Kahn
The contact/kinin and complement systems in vasculitis.
APMIS. Supplementum 2009;(127):48-54.
2009: Minola Manea; Diana Karpman
Molecular basis of ADAMTS13 dysfunction in thrombotic thrombocytopenic purpura.
Pediatric nephrology (Berlin, Germany) 2009;24(3):447-58.
2009: Anne-lie Ståhl; Lisa Sartz; Anders Nelsson; Zivile D Békássy; Diana Karpman
Shiga toxin and lipopolysaccharide induce platelet-leukocyte aggregates and tissue factor release, a thrombotic mechanism in hemolytic uremic syndrome.
PloS one 2009;4(9):e6990.
2008: Carla Calderon Toledo; Trisha Jayne Rogers; Majlis Svensson; Ramesh Tati; Hans Fischer; Catharina Svanborg; Diana Karpman
Shiga toxin-mediated disease in MyD88-deficient mice infected with Escherichia coli O157:H7.
The American journal of pathology 2008;173(5):1428-39.
2008: B Ragnarsdóttir; Hans Fischer; Gabriela Godaly; J Grönberg-Hernandez; Mattias Gustafsson; Diana Karpman; Ann-Charlotte Lundstedt; N Lutay; S Rämisch; Malin Svensson; Björn Wullt; M Yadav; Catharina Svanborg
TLR- and CXCR1-dependent innate immunity: insights into the genetics of urinary tract infections.
European journal of clinical investigation 2008;38 Suppl 2():12-20.
2008: Anne-lie Ståhl; Fariba Vaziri-Sani; Stefan Heinen; AnnCharlotte Kristoffersson; Karl-Henrik Gydell; Reem Raafat; Alberto Gutierrez; Ortraud Beringer; PF Zipfel; Diana Karpman
Factor H dysfunction in patients with atypical hemolytic uremic syndrome contributes to complement deposition on platelets and their activation.
Blood 2008;111(11):5307-15.
2008: Diana Karpman
[Hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Current perspectives on EHEC, complement mutations and ADAMTS13].
Läkartidningen 2008;105(15):1096-101.
2008: L Sartz; Birgitta de Jong; Marika Hjertqvist; L Plym-Forshell; R Alsterlund; S Löfdahl; B Osterman; A Ståhl; E Eriksson; H-B Hansson; Diana Karpman
An outbreak of Escherichia coli O157:H7 infection in southern Sweden associated with consumption of fermented sausage; aspects of sausage production that increase the risk of contamination.
Epidemiology and infection 2008;136(3):370-80.
2008: David Kavanagh; Anna Richards; Marina Noris; Richard Hauhart; M Kathryn Liszewski; Diana Karpman; Judith A Goodship; Veronique Fremeaux-Bacchi; Giuseppe Remuzzi; Timothy H J Goodship; John P Atkinson
Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome.
Molecular immunology 2008;45(1):95-105.
2007: Minola Manea; AnnCharlotte Kristoffersson; Reinhard Schneppenheim; Moin A Saleem; Peter W Mathieson; Matthias Mörgelin; Peter Björk; Lars Holmberg; Diana Karpman
Podocytes express ADAMTS13 in normal renal cortex and in patients with thrombotic thrombocytopenic purpura.
British journal of haematology 2007;138(5):651-62.
2007: Bryndís Ragnarsdóttir; Martin Samuelsson; Mattias Gustafsson; Irene Leijonhufvud; Diana Karpman; Catharina Svanborg
Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria.
The Journal of infectious diseases 2007;196(3):475-84.
2007: Ann-Charlotte Lundstedt; Irene Leijonhufvud; Bryndis Ragnarsdottir; Diana Karpman; Björn Andersson; Catharina Svanborg
Inherited susceptibility to acute pyelonephritis: a family study of urinary tract infection.
The Journal of infectious diseases 2007;195(8):1227-34.
2007: Minola Manea; AnnCharlotte Kristoffersson; Han-Mou Tsai; Wenhua Zhou; Ingemar Winqvist; Göran Oldaeus; Rolf Billström; Peter Björk; Lars Holmberg; Diana Karpman
ADAMTS13 phenotype in plasma from normal individuals and patients with thrombotic thrombocytopenic purpura.
European journal of pediatrics 2007;166(3):249-57.
2007: Sara C Nilsson; Diana Karpman; Fariba Vaziri-Sani; AnnCharlotte Kristoffersson; Rémi Salomon; Francois Provot; Veronique Fremeaux-Bacchi; Leendert A Trouw; Anna Blom
A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation.
Molecular immunology 2007;44(8):1835-44.
2007: Diana Karpman; Anna Blom; Timothy H J Goodship; Kathleen E Sullivan
Anguish over angiopathy: hemolytic uremic syndrome.
Clinical immunology (Orlando, Fla.) 2007;122(2):135-8.
2007: Ann-Charlotte Lundstedt; Shane McCarthy; Mattias Gustafsson; Gabriela Godaly; Ulf Jodal; Diana Karpman; Irene Leijonhufvud; Carin Lindén; Jeanette Martinell; Bryndis Ragnarsdottir; Martin Samuelsson; Lennart Truedsson; Björn Andersson; Catharina Svanborg
A genetic basis of susceptibility to acute pyelonephritis.
PloS one 2007;2(9):e825.
2006: N Besbas; Diana Karpman; D Landau; Chantal Loirat; Willem Proesmans; G Remuzzi; G Rizzoni; C M Taylor; Nicole C A J van de Kar; Lothar B Zimmerhackl
A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders.
Kidney international 2006;70(3):423-31.
2006: Reinhard Schneppenheim; Johanna A Kremer-Hovinga; Tim Becker; Ulrich Budde; Diana Karpman; Wolfgang Brockhaus; Ingrid Hrachovinová; Bartosz Korczowski; Florian Oyen; Simon Rittich; Johannes von Rosen; Geir Tjønnfjord; John E Pimanda; Thomas F Wienker; Bernhard Lämmle
A common origin of the 4143insA ADAMTS13 mutation.
Thrombosis and haemostasis 2006;96(1):3-6.
2006: Anne-lie Ståhl; Majlis Svensson; Matthias Mörgelin; Catharina Svanborg; Phillip I Tarr; Jody C Mooney; Sandra L Watkins; Roger Johnson; Diana Karpman
Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome.
Blood 2006;108(1):167-76.
2006: Diana Karpman; Minola Manea; Fariba Vaziri-Sani; Anne-Lie Ståhl; AnnCharlotte Kristoffersson
Platelet activation in hemolytic uremic syndrome.
Seminars in thrombosis and hemostasis 2006;32(2):128-45.
2006: Lothar B Zimmerhackl; Nesir Besbas; Therese C Jungraithmayr; Nicole C A J van de Kar; Helge Karch; Diana Karpman; Daniel Landau; Chantal Loirat; Willem Proesmans; Friederike Prüfer; Gianfranco Rizzoni; Mark C Taylor
Epidemiology, clinical presentation, and pathophysiology of atypical and recurrent hemolytic uremic syndrome.
Seminars in thrombosis and hemostasis 2006;32(2):113-20.
2006: Fariba Vaziri-Sani; Lars Holmberg; A G Sjöholm; AnnCharlotte Kristoffersson; Minola Manea; V Frémeaux-Bacchi; I Fehrman-Ekholm; R Raafat; Diana Karpman
Phenotypic expression of factor H mutations in patients with atypical hemolytic uremic syndrome.
Kidney international 2006;69(6):981-8.
2006: Catharina Svanborg; Göran Bergsten; Hans Fischer; Gabriela Godaly; Mattias Gustafsson; Diana Karpman; Ann-Charlotte Lundstedt; Bryndis Ragnarsdottir; Majlis Svensson; Björn Wullt
Uropathogenic Escherichia coli as a model of host-parasite interaction.
Current opinion in microbiology 2006;9(1):33-9.
2005: Fariba Vaziri-Sani; J Hellwage; P F Zipfel; A G Sjöholm; R Iancu; Diana Karpman
Factor H binds to washed human platelets.
Journal of thrombosis and haemostasis : JTH 2005;3(1):154-62.
2004: Ann-Christine Sjögren; James B Kaper; A Caprioli; Diana Karpman
Enzyme-linked immunosorbent assay for detection of Shiga toxin-producing Escherichia coli infection by antibodies to Escherichia coli secreted protein B in children with hemolytic uremic syndrome.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2004;23(3):208-11.
2003: Björn Wullt; Göran Bergsten; Hans Fischer; Gabriela Godaly; Diana Karpman; Irene Leijonhufvud; Ann-Charlotte Lundstedt; Patrik Samuelsson; Martin Samuelsson; Malin Svensson; Catharina Svanborg
The host response to urinary tract infection.
Infectious disease clinics of North America 2003;17(2):279-301.
2003: Karin Assink; Rikke Schiphorst; Sarah Allford; Diana Karpman; Amos Etzioni; Bénédicte Brichard; Nicole C A J van de Kar; Leo Monnens; Lambert van Den Heuvel
Mutation analysis and clinical implications of von Willebrand factor-cleaving protease deficiency.
Kidney international 2003;63(6):1995-9.
2002: Lars Hjorth; Thomas Wiebe; Diana Karpman
Correct evaluation of renal glomerular filtration rate requires clearance assays.
Pediatric nephrology (Berlin, Germany) 2002;17(10):847-51.
2002: Robin Kahn; Heiko Herwald; Werner Müller-Esterl; Roland Schmitt; Ann-Christine Sjögren; Lennart Truedsson; Diana Karpman
Contact-system activation in children with vasculitis.
Lancet 2002;360(9332):535-41.
2002: Diana Karpman; Zivile D Békássy; Ann-Christine Sjögren; Maria S Dubois; Mohamed A Karmali; Mariola Mascarenhas; Karen G Jarvis; Lisa J Gansheroff; Alison D O'Brien; Gerald S Arbus; James B Kaper
Antibodies to intimin and Escherichia coli secreted proteins A and B in patients with enterohemorrhagic Escherichia coli infections.
Pediatric nephrology (Berlin, Germany) 2002;17(3):201-11.
2002: Mirjana Poljakovic; Diana Karpman; Catharina Svanborg; Katarina Persson
Human renal epithelial cells express iNOS in response to cytokines but not bacteria.
Kidney international 2002;61(2):444-55.
2001: Catharina Svanborg; Göran Bergsten; Hans Fischer; B Frendéus; Gabriela Godaly; Elisabeth Gustafsson; Long Hang; M Hedlund; Diana Karpman; Ann-Charlotte Lundstedt; Martin Samuelsson; Patrik Samuelsson; Malin Svensson; Björn Wullt
The 'innate' host response protects and damages the infected urinary tract.
Annals of medicine 2001;33(9):563-70.
2001: Diana Karpman; D Papadopoulou; K Nilsson; Ann-Christine Sjögren; C Mikaelsson; Stefan Lethagen
Platelet activation by Shiga toxin and circulatory factors as a pathogenetic mechanism in the hemolytic uremic syndrome.
Blood 2001;97(10):3100-8.
2001: B Frendéus; Gabriela Godaly; Long Hang; Diana Karpman; Catharina Svanborg
Interleukin-8 receptor deficiency confers susceptibility to acute pyelonephritis.
The Journal of infectious diseases 2001;183 Suppl 1():S56-60.
2001: M Hedlund; R D Duan; A Nilsson ; Malin Svensson; Diana Karpman; Catharina Svanborg
Fimbriae, transmembrane signaling, and cell activation.
The Journal of infectious diseases 2001;183 Suppl 1():S47-50.
2000: B Frendéus; Gabriela Godaly; Long Hang; Diana Karpman; Ann-Charlotte Lundstedt; Catharina Svanborg
Interleukin 8 receptor deficiency confers susceptibility to acute experimental pyelonephritis and may have a human counterpart.
The Journal of experimental medicine 2000;192(6):881-90.
2000: Gabriela Godaly; Göran Bergsten; B Frendéus; Long Hang; M Hedlund; Diana Karpman; Patrik Samuelsson; Malin Svensson; G Otto; Björn Wullt; Catharina Svanborg
Innate defences and resistance to gram negative mucosal infection.
Advances in experimental medicine and biology 2000;485():9-24.
1998: Long Hang; Björn Wullt; Z Shen; Diana Karpman; Catharina Svanborg
Cytokine repertoire of epithelial cells lining the human urinary tract.
The Journal of urology 1998;159(6):2185-92.
1998: Lars Holmberg; Diana Karpman; Christina Isaksson; AnnCharlotte Kristoffersson; Stefan Lethagen; Reinhard Schneppenheim
Ins405AsnPro mutation in the von Willebrand factor propeptide in recessive type 2A (IIC) von Willebrand's disease.
Thrombosis and haemostasis 1998;79(4):718-22.
1998: Diana Karpman; A Håkansson; M T Perez; Christina Isaksson; E Carlemalm; A Caprioli; Catharina Svanborg
Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: in vivo and in vitro studies.
Infection and immunity 1998;66(2):636-44.
1997: Diana Karpman; Stefan Lethagen; AnnCharlotte Kristoffersson; Christina Isaksson; Lars Holmberg
von Willebrand factor mediates increased platelet retention in recurrent thrombotic thrombocytopenic purpura.
Thrombosis and haemostasis 1997;78(6):1456-62.
1997: L Holmberg; Diana Karpman; I Nilsson; Tor Olofsson
Bernard-Soulier syndrome Karlstad: Trp 498-->Stop mutation resulting in a truncated glycoprotein Ib alpha that contains part of the transmembranous domain.
British journal of haematology 1997;98(1):57-63.
1997: Diana Karpman; H Connell; M Svensson; F Scheutz; P Alm; Catharina Svanborg
The role of lipopolysaccharide and Shiga-like toxin in a mouse model of Escherichia coli O157:H7 infection.
The Journal of infectious diseases 1997;175(3):611-20.
1996: M Donnér; Diana Karpman; A C Kristoffersson; I Winqvist; L Holmberg
Recurrent mutation Asn45-->Ser of glycoprotein IX in Bernard-Soulier syndrome.
European journal of haematology 1996;57(2):178-9.
1996: Diana Karpman; L Holmberg; L Jirgård; Stefan Lethagen
Increased platelet retention in familial recurrent thrombotic thrombocytopenic purpura.
Kidney international 1996;49(1):190-9.
1995: Diana Karpman; A Andreasson; H Thysell; B S Kaplan; Catharina Svanborg
Cytokines in childhood hemolytic uremic syndrome and thrombotic thrombocytopenic purpura.
Pediatric nephrology (Berlin, Germany) 1995;9(6):694-9.