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Soo Bae

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C Y Ahn; Soo K Bae; S H Bae; Hae-Eun Kang; Seok-Ho Kim; Myung Gull Lee; Wan G Shin
Pharmacokinetics of sildenafil and its metabolite, N-desmethylsildenafil, in rats with liver cirrhosis and diabetes mellitus, alone and in combination.
Soo H Bae; Soo K Bae; Myung G Lee
Effect of hepatic CYP inhibitors on the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in rats in vitro and in vivo.
Soo K Bae; Kyung H Yang; Dipendra K Aryal; Yoon G Kim; Myung G Lee
Pharmacokinetics of amitriptyline and one of its metabolites, nortriptyline, in rats: little contribution of considerable hepatic first-pass effect to low bioavailability of amitriptyline due to great intestinal first-pass effect.

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All Publications

2011: C Y Ahn; Soo K Bae; S H Bae; Hae-Eun Kang; Seok-Ho Kim; Myung Gull Lee; Wan G Shin
Pharmacokinetics of sildenafil and its metabolite, N-desmethylsildenafil, in rats with liver cirrhosis and diabetes mellitus, alone and in combination.
Xenobiotica; the fate of foreign compounds in biological systems 2011;41(2):164-74.
2009: Soo H Bae; Soo K Bae; Myung G Lee
Effect of hepatic CYP inhibitors on the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in rats in vitro and in vivo.
The Journal of pharmacy and pharmacology 2009;61(12):1637-42.
2009: Soo K Bae; Kyung H Yang; Dipendra K Aryal; Yoon G Kim; Myung G Lee
Pharmacokinetics of amitriptyline and one of its metabolites, nortriptyline, in rats: little contribution of considerable hepatic first-pass effect to low bioavailability of amitriptyline due to great intestinal first-pass effect.
Journal of pharmaceutical sciences 2009;98(4):1587-601.
2009: Hae-Eun Kang; Soo K Bae; M Yoo; D C Lee; Y G Kim; Myung Gull Lee
Interaction between udenafil and tamsulosin in rats: non-competitive inhibition of tamsulosin metabolism by udenafil via hepatic CYP3A1/2.
British journal of pharmacology 2009;156(6):1009-18.
2009: Choong Y Ahn; Soo K Bae; S H Bae; Taekrho Kim; Yi-Sook Jung; Young Choong Kim; Myung Gull Lee; Wan G Shin
Pharmacokinetics of oltipraz in diabetic rats with liver cirrhosis.
British journal of pharmacology 2009;156(6):1019-28.
2008: Choong Y Ahn; Soo K Bae; Yi-Sook Jung; Inchul Lee; Young C Kim; Myung G Lee; Wan G Shin
Pharmacokinetic parameters of chlorzoxazone and its main metabolite, 6-hydroxychlorzoxazone, after intravenous and oral administration of chlorzoxazone to liver cirrhotic rats with diabetes mellitus.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(7):1233-41.
2007: Hye D Choi; Hee E Kang; Hye J Chung; Soo K Bae; Karen N Shin; Myung G Lee
Effects of water deprivation on the pharmacokinetics of theophylline and one of its metabolites, 1,3-dimethyluric acid, after intravenous and oral administration of aminophylline to rats.
Biopharmaceutics & drug disposition 2007;28(8):445-54.
2007: Young H Choi; Soo K Bae; Jung Mi Oh; Sun-Ok Kim; Myung G Lee
Pharmacokinetics of intravenous methotrexate in mutant Nagase analbuminemic rats.
Biopharmaceutics & drug disposition 2007;28(7):385-92.
2007: Soo K Bae; Si H Yang; Karen N Shin; Jae Keol Rhee; Moohi Yoo; Myung G Lee
Pharmacokinetics of DA-7218, a new oxazolidinone, and its active metabolite, DA-7157, after intravenous and oral administration of DA-7218 and DA-7157 to rats.
The Journal of pharmacy and pharmacology 2007;59(7):955-63.
2007: Young H Choi; Soo K Bae; Sun O Kim; Myung G Lee
Pharmacokinetics of 5-fluorouracil in mutant Nagase analbuminemic rats: faster metabolism of 5-fluorouracil via CYP1A.
Biopharmaceutics & drug disposition 2007;28(2):87-95.
2006: Hye W Baek; Soo K Bae; Myung G Lee; Young T Sohn
Pharmacokinetics of chlorzoxazone in rats with diabetes: Induction of CYP2E1 on 6-hydroxychlorzoxazone formation.
Journal of pharmaceutical sciences 2006;95(11):2452-62.
2006: Hyun S Shin; Soo K Bae; Myung G Lee
Pharmacokinetics of sildenafil after intravenous and oral administration in rats: hepatic and intestinal first-pass effects.
International journal of pharmaceutics 2006;320(1-2):64-70.
2006: Dae Y Lee; Hyun S Shin; Soo K Bae; Myung G Lee
Effects of enzyme inducers and inhibitors on the pharmacokinetics of intravenous omeprazole in rats.
Biopharmaceutics & drug disposition 2006;27(5):209-18.
2006: Soo K Bae; Shin J Lee; Taekrho Kim; Jin W Kim; Inchul Lee; Sang G Kim; Myung G Lee
Pharmacokinetics and therapeutic effects of oltipraz after consecutive or intermittent oral administration in rats with liver cirrhosis induced by dimethylnitrosamine.
Journal of pharmaceutical sciences 2006;95(5):985-97.
2006: Soo K Bae; Hee E Kang; Min K Kang; Jin W Kim; Taekrho Kim; Myung G Lee
Pharmacokinetics of oltipraz in mutant Nagase analbuminemic rats.
Journal of pharmaceutical sciences 2006;95(5):998-1005.
2006: Soo K Bae; Ji Young Kim; Si Hyung Yang; Jin Wan Kim; Taekrho Kim; Myung Gull Lee
Pharmacokinetics of oltipraz in rat models of diabetes mellitus induced by alloxan or streptozotocin.
Life sciences 2006;78(20):2287-94.
2006: Soo K Bae; Yu C Kim; Jae K Lee; Jong W Kwon; Moohi Yoo; Inchul Lee; Myung G Lee
Effects of water deprivation for 72 hours on the pharmacokinetics of DA-7867, a new oxazolidinone, in rats.
Biopharmaceutics & drug disposition 2006;27(3):147-56.
2006: Soo K Bae; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Effects of acute renal failure on the pharmacokinetics of DA-7867, a new oxazolidinone, in rats.
Biopharmaceutics & drug disposition 2006;27(1):29-37.
2006: Si H Yang; Soo K Bae; Jong W Kwon; Moohi Yoo; Myung G Lee
Gender differences in the pharmacokinetics of DA-6034, a derivative of flavonoids, in rats.
Biopharmaceutics & drug disposition 2006;27(1):47-51.
2005: Joo H Lee; Soo K Bae; Jong W Kwon; Won Bae Kim; Myung G Lee
Effects of omeprazole or cola beverage on the pharmacokinetics of oral DA-8159, a new erectogenic, in rats.
Biopharmaceutics & drug disposition 2005;26(9):411-6.
2005: Shin Jung Lee; Soo K Bae; Jong Won Kwon; Moohi You; Duk-Chul Lee; Myung Gull Lee
Pharmacokinetic interaction between 5-[2-propyloxy-5-(1-methyl-2-pyrollidinylethylamidosulfonyl)phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo (4,3-d) pyrimidine-7-one (DA-8159) and nitroglycerin in rats.
The Journal of pharmacy and pharmacology 2005;57(11):1397-405.
2005: Soo K Bae; Si H Yang; Jin W Kim; Taekrho Kim; Jong W Kwon; Myung G Lee
Effects of cysteine on the pharmacokinetics of oltipraz in rats with protein-calorie malnutrition.
Journal of pharmaceutical sciences 2005;94(7):1484-93.
2005: Soo K Bae; Si H Yang; Shin J Lee; Jong W Kwon; Won Bae Kim; Duk-Chul Lee; Myung G Lee
Pharmacokinetic changes of DA-7867, a new oxazolidinone, after intravenous and oral administration to rats with short-term and long-term diabetes mellitus induced by streptozotocin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;25(2-3):337-45.
2005: Soo K Bae; Jin W Kim; Young H Kim; Yoon G Kim; Sang G Kim; Myung G Lee
Hepatic and intestinal first-pass effects of oltipraz in rats.
Biopharmaceutics & drug disposition 2005;26(4):129-34.
2005: Soo K Bae; Shin Jung Lee; Young Hoon Kim; Taekrho Kim; Myung Gull Lee
Effect of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats.
The Journal of pharmacy and pharmacology 2005;57(4):443-52.
2005: Soo K Bae; Shin J Lee; Yoon G Kim; So H Kim; Jin W Kim; Taekrho Kim; Myung G Lee
Interspecies pharmacokinetic scaling of oltipraz in mice, rats, rabbits and dogs, and prediction of human pharmacokinetics.
Biopharmaceutics & drug disposition 2005;26(3):99-115.
2005: Young H Choi; Ae K Lee; Soo K Bae; Sun O Kim; Myung G Lee
Pharmacokinetics of 5-fluorouracil in rats with diabetes mellitus induced by streptozotocin.
Biopharmaceutics & drug disposition 2005;26(3):93-8.
2005: Soo K Bae; Eun J Kim; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Excretion and metabolism of DA-7867, a new oxazolidinone, in rats.
Biopharmaceutics & drug disposition 2005;26(2):67-75.
2005: Soo K Bae; Shin J Lee; Jin W Kim; Young H Kim; Sang G Kim; Myung G Lee
Pharmacokinetics of oltipraz after intravenous and oral administration in rats with dehydration for 72 hours.
Biopharmaceutics & drug disposition 2005;26(2):77-83.
2004: Soo K Bae; Dae Y Lee; Ae K Lee; Jong W Kwon; Inchul Lee; Suk-Jae Chung; Sang G Kim; Chang-Koo Shim; Myung G Lee
Effects of cysteine on the pharmacokinetics of intravenous torasemide in rats with protein-calorie malnutrition.
Journal of pharmaceutical sciences 2004;93(9):2388-98.
2004: Soo K Bae; Shin J Lee; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Effects of bacterial lipopolysaccharide on the pharmacokinetics of DA-7867, a new oxazolidinone, in rats.
Journal of pharmaceutical sciences 2004;93(9):2364-73.
2004: Soo K Bae; Shin J Lee; Jin W Kim; Young H Kim; Sang G Kim; Myung G Lee
Effects of acute renal failure on the pharmacokinetics of oltipraz in rats.
Journal of pharmaceutical sciences 2004;93(9):2353-63.
2004: Soo K Bae; Shin J Lee; Jang Y Lee; Youngsoo Lee; Inchul Lee; Sang G Kim; Myung G Lee
Pharmacokinetic changes of oltipraz after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine.
International journal of pharmaceutics 2004;275(1-2):227-38.
2004: Soo K Bae; Shin Jung Lee; Jong Won Kwon; Won Bae Kim; Myung Gull Lee
Effects of protein-calorie malnutrition on the pharmacokinetics of DA-7867, a new oxazolidinone, in rats.
The Journal of pharmacy and pharmacology 2004;56(5):635-42.
2004: Soo K Bae; Won-S Chung; Eun J Kim; Jae Keol Rhee; Jong W Kwon; Won Bae Kim; Myung G Lee
Pharmacokinetics, blood partition and protein binding of DA-7867, a new oxazolidinone.
Biopharmaceutics & drug disposition 2004;25(3):127-35.
2004: Soo K Bae; Won-Suk Chung; Eun J Kim; Jae Keol Rhee; Jong W Kwon; Won Bae Kim; Myung G Lee
Pharmacokinetics of DA-7867, a new oxazolidinone, after intravenous or oral administration to rats: intestinal first-pass effect.
Antimicrobial agents and chemotherapy 2004;48(2):659-62.
2003: Soo K Bae; Eun Jung Kim; Suk-Jae Chung; Sang Geon Kim; Myung Gull Lee
Pharmacokinetic interaction between oltipraz and dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB) after single intravenous and oral administration to rats.
The Journal of pharmacy and pharmacology 2003;55(9):1241-9.
2003: Su Yeon Yu; Soo K Bae; Eun Jung Kim; Yoon Gyoon Kim; Sun-Ok Kim; Dong Ha Lee; Hong Lim; Myung Gull Lee
Dose-independent pharmacokinetics of a new reversible proton pump inhibitor, KR-60436, after intravenous and oral administration to rats: gastrointestinal first-pass effect.
Journal of pharmaceutical sciences 2003;92(8):1592-603.
2003: Eun J Kim; Soo K Bae; Hee J Kim; Yoon G Kim; Sun-O Kim; Dong H Lee; Hong Lim; Myung G Lee
Dose-independent pharmacokinetics of a candidate for diabetic neuropathy, SR-4668, after intravenous and oral administration to rats: Intestinal first-pass effect.
Journal of pharmaceutical sciences 2003;92(5):1112-24.
2003: Mi H Lee; Soo K Bae; Eun J Kim; Yoon G Kim; Sun-O Kim; Dong H Lee; Hong Lim; Sung-E Yoo; Myung G Lee
Dose-independent pharmacokinetics of a new neuroprotective agent for ischemia-reperfusion damage, KR-31543, after intravenous and oral administration to rats: hepatic and intestinal first-pass effects.
Journal of pharmaceutical sciences 2003;92(1):190-201.