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Younsoo Bae

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TOP 3
Daniel Scott; Younsoo Bae; Jhong-Min Chen; Jürgen Rohr
Semi-Synthetic Mithramycin SA Derivatives with Improved AntiCancer Activity.
Karen S Jackson; Younsoo Bae; Youngmi Han; Jihyun Yeom; Chongsuk Ryou
Preference toward a polylysine enantiomer in inhibiting prions.
Mo Dan; Peter A Hardy; J Zachary Hilt; Daniel F Scott; Robert J Wydra; Robert A Yokel; Younsoo Bae
Block copolymer cross-linked nanoassemblies improve particle stability and biocompatibility of superparamagnetic iron oxide nanoparticles.

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All Publications

2013: Daniel Scott; Younsoo Bae; Jhong-Min Chen; Jürgen Rohr
Semi-Synthetic Mithramycin SA Derivatives with Improved AntiCancer Activity.
Chemical biology & drug design 2013;81(5):615-24.
2013: Karen S Jackson; Younsoo Bae; Youngmi Han; Jihyun Yeom; Chongsuk Ryou
Preference toward a polylysine enantiomer in inhibiting prions.
Amino acids 2013;44(3):993-1000.
2013: Mo Dan; Peter A Hardy; J Zachary Hilt; Daniel F Scott; Robert J Wydra; Robert A Yokel; Younsoo Bae
Block copolymer cross-linked nanoassemblies improve particle stability and biocompatibility of superparamagnetic iron oxide nanoparticles.
Pharmaceutical research 2013;30(2):552-61.
2013: Hyun Jin Lee; Younsoo Bae
Pharmaceutical differences between block copolymer self-assembled and cross-linked nanoassemblies as carriers for tunable drug release.
Pharmaceutical research 2013;30(2):478-88.
2012: Pengxiao Cao; Younsoo Bae
Polymer nanoparticulate drug delivery and combination cancer therapy.
Future oncology (London, England) 2012;8(11):1471-80.
2012: Allison M Eckman; Nayon Y Kang; Andrei Ponta; Eleftheria Tsakalozou; Younsoo Bae
Drug release patterns and cytotoxicity of PEG-poly(aspartate) block copolymer micelles in cancer cells.
Pharmaceutical research 2012;29(7):1755-67.
2012: Shuqian Liu; Sumitra Miriyala; Daret K St Clair; Younsoo Bae; Saloni Bhatnagar; Abigail Daily; Markos Leggas; Jeffrey A Moscow
Pharmacologic properties of polyethylene glycol-modified Bacillus thiaminolyticus thiaminase I enzyme.
The Journal of pharmacology and experimental therapeutics 2012;341(3):775-83.
2012: Tze-Haw H Chen; Darin Yale Furgeson; Younsoo Bae; Glen S Kwon
Biodegradable hybrid recombinant block copolymers for non-viral gene transfection.
International journal of pharmaceutics 2012;427(1):105-12.
2012: Shanjida Akter; Jason Chesney; Brian F Clem; Hyun Jin Lee; Younsoo Bae
Block copolymer micelles for controlled delivery of glycolytic enzyme inhibitors.
Pharmaceutical research 2012;29(3):847-55.
2012: Eleftheria Tsakalozou; Allison M Eckman; Younsoo Bae
Combination effects of docetaxel and Doxorubicin in hormone-refractory prostate cancer cells.
Biochemistry research international 2012;2012():832059.
2011: Melissa D Howard; Michael Jay; Andrei Ponta; Allison Eckman; Younsoo Bae
Polymer micelles with hydrazone-ester dual linkers for tunable release of dexamethasone.
Pharmaceutical research 2011;28(10):2435-46.
2011: Abigail Daily; Shuqian Liu; Younsoo Bae; Saloni Bhatnagar; Jeffrey A Moscow
Linear chain PEGylated recombinant Bacillus thiaminolyticus thiaminase I enzyme has growth inhibitory activity against lymphoid leukemia cell lines.
Molecular cancer therapeutics 2011;10(9):1563-70.
2011: Hyun Jin Lee; Younsoo Bae
Cross-linked nanoassemblies from poly(ethylene glycol)-poly(aspartate) block copolymers as stable supramolecular templates for particulate drug delivery.
Biomacromolecules 2011;12(7):2686-96.
2011: Chongsuk Ryou; William B Titlow; Charles Mays; Younsoo Bae; Sehun Kim
The suppression of prion propagation using poly-L-lysine by targeting plasminogen that stimulates prion protein conversion.
Biomaterials 2011;32(11):3141-9.
2011: Daniel Scott; Jürgen Rohr; Younsoo Bae
Nanoparticulate formulations of mithramycin analogs for enhanced cytotoxicity.
International journal of nanomedicine 2011;6():2757-67.
2010: Hyun Jin Lee; Andrei Ponta; Younsoo Bae
Polymer nanoassemblies for cancer treatment and imaging.
Therapeutic delivery 2010;1(6):803-17.
2010: Younsoo Bae; Adam W G Alani; Nicole C Rockich; T S Z Chung Lai; Glen S Kwon
Mixed pH-sensitive polymeric micelles for combination drug delivery.
Pharmaceutical research 2010;27(11):2421-32.
2010: Andrei Ponta; Younsoo Bae
PEG-poly(amino acid) block copolymer micelles for tunable drug release.
Pharmaceutical research 2010;27(11):2330-42.
2010: Tsz Chung Lai; Younsoo Bae; Takayuki Yoshida; Kazunori Kataoka; Glen S Kwon
pH-sensitive multi-PEGylated block copolymer as a bioresponsive pDNA delivery vector.
Pharmaceutical research 2010;27(11):2260-73.
2010: Younsoo Bae
Drug delivery systems using polymer nanoassemblies for cancer treatment.
Therapeutic delivery 2010;1(3):361-3.
2010: Thomas A Diezi; Younsoo Bae; Glen S Kwon
Enhanced stability of PEG-block-poly(N-hexyl stearate l-aspartamide) micelles in the presence of serum proteins.
Molecular pharmaceutics 2010;7(4):1355-60.
2010: Adam W G Alani; Younsoo Bae; Deepa A Rao; Glen S Kwon
Polymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxel.
Biomaterials 2010;31(7):1765-72.
2009: Younsoo Bae; Kazunori Kataoka
Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers.
Advanced drug delivery reviews 2009;61(10):768-84.
2008: Tze-Haw Howard Chen; Younsoo Bae; Darin Yale Furgeson
Intelligent biosynthetic nanobiomaterials (IBNs) for hyperthermic gene delivery.
Pharmaceutical research 2008;25(3):683-91.
2007: Younsoo Bae; Thomas A Diezi; Anni Zhao; Glen S Kwon
Mixed polymeric micelles for combination cancer chemotherapy through the concurrent delivery of multiple chemotherapeutic agents.
Journal of controlled release : official journal of the Controlled Release Society 2007;122(3):324-30.
2007: Younsoo Bae; Rita A Buresh; Tracy P Williamson; Tze-Haw Howard Chen; Darin Yale Furgeson
Intelligent biosynthetic nanobiomaterials for hyperthermic combination chemotherapy and thermal drug targeting of HSP90 inhibitor geldanamycin.
Journal of controlled release : official journal of the Controlled Release Society 2007;122(1):16-23.
2007: May Xiong; Younsoo Bae; Shigeto Fukushima; M Laird Forrest; Nobuhiro Nishiyama; Kazunori Kataoka; Glen S Kwon
pH-responsive Multi-PEGylated dual cationic nanoparticles enable charge modulations for safe gene delivery.
ChemMedChem 2007;2(9):1321-7.
2007: Muri Han; Younsoo Bae; Nobuhiro Nishiyama; Kanjiro Miyata; Makoto Oba; Kazunori Kataoka
Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies.
Journal of controlled release : official journal of the Controlled Release Society 2007;121(1-2):38-48.
2007: Younsoo Bae; Nobuhiro Nishiyama; Kazunori Kataoka
In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments.
Bioconjugate chemistry 2007;18(4):1131-9.
2007: Yan Lee; Shigeto Fukushima; Younsoo Bae; Shigehiro Hiki; Takehiko Ishii; Kazunori Kataoka
A protein nanocarrier from charge-conversion polymer in response to endosomal pH.
Journal of the American Chemical Society 2007;129(17):5362-3.
2007: Mitsunobu R Kano; Younsoo Bae; Caname Iwata; Yasuyuki Morishita; Masakazu Yashiro; Masako Oka; Tomoko Fujii; Akiyoshi Komuro; Kunihiko Kiyono; Michio Kaminishi; Kosei Hirakawa; Yasuyoshi Ouchi; Nobuhiro Nishiyama; Kazunori Kataoka; Kohei Miyazono
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3460-5.
2006: Younsoo Bae; Kazunori Kataoka
Significant enhancement of antitumor activity and bioavailability of intracellular pH-sensitive polymeric micelles by folate conjugation.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e49-50.
2006: Younsoo Bae; Kazunori Kataoka
[Drug and gene delivery with nanotechnology].
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(9):882-7.
2005: Younsoo Bae; woo-dong Jang; Nobuhiro Nishiyama; Shigeto Fukushima; Kazunori Kataoka
Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery.
Molecular bioSystems 2005;1(3):242-50.
2005: Younsoo Bae; Nobuhiro Nishiyama; Shigeto Fukushima; Hiroyuki Koyama; Matsumura Yasuhiro; Kazunori Kataoka
Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy.
Bioconjugate chemistry 2005;16(1):122-30.
2003: Younsoo Bae; Shigeto Fukushima; Atsushi Harada; Kazunori Kataoka
Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change.
Angewandte Chemie (International ed. in English) 2003;42(38):4640-3.