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Arthur Kaser

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Arthur Kaser; Richard S Blumberg
Introduction: the unfolded protein response's role in disease pathophysiology.
Arthur Kaser; Timon Erik Adolph; Richard S Blumberg
The unfolded protein response and gastrointestinal disease.
Sebastian Zeissig; Alexander Arlt; Katharina Balschun; Jody L Baron; Esther Bosse; Rainer Günther; Jochen Hampe; Zongyi Hu; M Mahmood Hussain; Jahangir Iqbal; Arthur Kaser; T Jake Liang; D Branch Moody; Kazumoto Murata; Jean Publicover; Christoph Röcken; Stefan Schreiber; Lindsay Sweet; Richard S Blumberg
Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity.

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All Publications

2013: Arthur Kaser; Richard S Blumberg
Introduction: the unfolded protein response's role in disease pathophysiology.
Seminars in immunopathology 2013;35(3):255-7.
2013: Arthur Kaser; Timon Erik Adolph; Richard S Blumberg
The unfolded protein response and gastrointestinal disease.
Seminars in immunopathology 2013;35(3):307-19.
2012: Sebastian Zeissig; Alexander Arlt; Katharina Balschun; Jody L Baron; Esther Bosse; Rainer Günther; Jochen Hampe; Zongyi Hu; M Mahmood Hussain; Jahangir Iqbal; Arthur Kaser; T Jake Liang; D Branch Moody; Kazumoto Murata; Jean Publicover; Christoph Röcken; Stefan Schreiber; Lindsay Sweet; Richard S Blumberg
Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity.
Nature medicine 2012;18(7):1060-8.
2012: Arthur Kaser; Herbert Tilg
"Metabolic aspects" in inflammatory bowel diseases.
Current drug delivery 2012;9(4):326-32.
2012: Timon-Eric Adolph; Richard S Blumberg; Lukas Niederreiter; Arthur Kaser
Endoplasmic reticulum stress and inflammation.
Digestive diseases (Basel, Switzerland) 2012;30(4):341-6.
2011: Arthur Kaser; Michal F Tomczak; Magdalena B Flak; Richard S Blumberg
The unfolded protein response and its role in intestinal homeostasis and inflammation.
Experimental cell research 2011;317(19):2772-9.
2011: Arthur Kaser; Lukas Niederreiter; Richard S Blumberg
Genetically determined epithelial dysfunction and its consequences for microflora-host interactions.
Cellular and molecular life sciences : CMLS 2011;68(22):3643-9.
2011: Katharina Hoenisch; Martin Freund; Rupert Prommegger; Michael Schocke; Hubert Schwaighofer; Wolfgang Vogel; Arthur Kaser
Intramural duodenal hematoma after upper gastrointestinal endoscopy.
Wiener medizinische Wochenschrift (1946) 2011;161(17-18):441-4.
2011: Alexander R Moschen; Andrea Schroll; Teresa Fritz; Romana Gerner; Arthur Kaser; Herbert Tilg
A key role for Pre-B cell colony-enhancing factor in experimental hepatitis.
Hepatology (Baltimore, Md.) 2011;54(2):675-86.
2011: Lukas Niederreiter; Arthur Kaser
Endoplasmic reticulum stress and inflammatory bowel disease.
Acta gastro-enterologica Belgica 2011;74(2):330-3.
2011: Arthur Kaser; Richard S Blumberg
Autophagy, microbial sensing, endoplasmic reticulum stress, and epithelial function in inflammatory bowel disease.
Gastroenterology 2011;140(6):1738-47.
2011: Arthur Kaser; Richard S Blumberg
Lessons from type I interferons in ulcerative colitis.
Gut 2011;60(4):430-1.
2011: Arthur Kaser; Michal Tomczak; Richard S Blumberg
"ER stress(ed out)!": Paneth cells and ischemia-reperfusion injury of the small intestine.
Gastroenterology 2011;140(2):393-6.
2010: Herbert Tilg; Arthur Kaser
Vedolizumab, a humanized mAb against the α4β7 integrin for the potential treatment of ulcerative colitis and Crohn's disease.
Current opinion in investigational drugs (London, England : 2000) 2010;11(11):1295-304.
2010: Teresa Fritz; Lukas Niederreiter; Herbert Tilg; Richard S Blumberg; Arthur Kaser
Controversy over NOD2, inflammation, and defensins.
Inflammatory bowel diseases 2010;16(11):1996-8.
2010: Alexander R Moschen; Clemens Molnar; Sabine Geiger; Ivo W Graziadei; Christoph Ebenbichler; Helmut Weiss; Susanne Kaser; Arthur Kaser; Herbert Tilg
Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor alpha expression.
Gut 2010;59(9):1259-64.
2010: Arthur Kaser; Richard S Blumberg
Survive an innate immune response through XBP1.
Cell research 2010;20(5):506-7.
2010: Arthur Kaser; Sebastian Zeissig; Richard S Blumberg
Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future?
Digestive diseases (Basel, Switzerland) 2010;28(3):395-405.
2010: Arthur Kaser; Sebastian Zeissig; Richard S Blumberg
Inflammatory bowel disease.
Annual review of immunology 2010;28():573-621.
2009: Herbert Tilg; Arthur Kaser
Adiponectin and JNK: metabolic/inflammatory pathways affecting gastrointestinal carcinogenesis.
Gut 2009;58(12):1576-7.
2009: Arthur Kaser; Richard S Blumberg
Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease.
Seminars in immunology 2009;21(3):156-63.
2009: Herbert Tilg; Alexander R Moschen; Arthur Kaser
Obesity and the microbiota.
Gastroenterology 2009;136(5):1476-83.
2009: Herbert Tilg; Alexander R Moschen; Arthur Kaser
Suppression of interleukin-17 by type I interferons: a contributing factor in virus-induced immunosuppression?
European cytokine network 2009;20(1):1-6.
2009: Arthur Kaser; Herbert Tilg
Inflammatory bowel diseases: highlights from the United European Gastroenterology Week 2008.
Expert opinion on therapeutic targets 2009;13(2):259-63.
2008: Arthur Kaser; Richard S Blumberg
Paneth cells and inflammation dance together in Crohn's disease.
Cell research 2008;18(12):1160-2.
2008: Arthur Kaser; Ann-Hwee Lee; Andre Franke; Jonathan N Glickman; Sebastian Zeissig; Herbert Tilg; Edward E S Nieuwenhuis; Darren E Higgins; Stefan Schreiber; Laurie H Glimcher; Richard S Blumberg
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.
Cell 2008;134(5):743-56.
2008: Arthur Kaser; David L Hava; Stephanie K Dougan; Zhangguo Chen; Sebastian Zeissig; Michael B Brenner; Richard S Blumberg
Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules.
European journal of immunology 2008;38(8):2351-9.
2008: Arthur Kaser; Richard S Blumberg
Adaptive immunity in inflammatory bowel disease: state of the art.
Current opinion in gastroenterology 2008;24(4):455-61.
2008: Arthur Kaser; Herbert Tilg
Novel therapeutic targets in the treatment of IBD.
Expert opinion on therapeutic targets 2008;12(5):553-63.
2008: Herbert Tilg; Alexander R Moschen; Arthur Kaser; A Pines; I Dotan
Gut, inflammation and osteoporosis: basic and clinical concepts.
Gut 2008;57(5):684-94.
2008: Alexander R Moschen; Sabine Geiger; Ingomar Krehan; Arthur Kaser; Herbert Tilg
Interferon-alpha controls IL-17 expression in vitro and in vivo.
Immunobiology 2008;213(9-10):779-87.
2007: Herbert Tilg; Alexander R Moschen; Arthur Kaser
Mode of function of biological anti-TNF agents in the treatment of inflammatory bowel diseases.
Expert opinion on biological therapy 2007;7(7):1051-9.
2007: Alexander R Moschen; Arthur Kaser; Barbara Enrich; Birgit A Mosheimer; Milan Theurl; Harald Niederegger; Herbert Tilg
Visfatin, an adipocytokine with proinflammatory and immunomodulating properties.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1748-58.
2006: Herbert Tilg; Arthur Kaser; Alexander R Moschen
How to modulate inflammatory cytokines in liver diseases.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(9):1029-39.
2005: Alexander R Moschen; Arthur Kaser; Sylvia Stadlmann; Gunda Millonig; Susanne Kaser; Petra Mühllechner; Andrzej Habior; Ivo W Graziadei; Wolfgang Vogel; Herbert Tilg
The RANKL/OPG system and bone mineral density in patients with chronic liver disease.
Journal of hepatology 2005;43(6):973-83.
2005: Susanne Kaser; Alexander R Moschen; Arthur Kaser; Othmar Ludwiczek; Christoph Ebenbichler; Wolfgang Vogel; Werner Jaschke; Josef R Patsch; Herbert Tilg
Circulating adiponectin reflects severity of liver disease but not insulin sensitivity in liver cirrhosis.
Journal of internal medicine 2005;258(3):274-80.
2005: Herbert Tilg; Arthur Kaser
Predicting mortality by the Glasgow alcoholic hepatitis score: the long awaited progress?
Gut 2005;54(8):1057-9.
2005: Alexander R Moschen; Arthur Kaser; Barbara Enrich; Othmar Ludwiczek; M Gabriel; P Obrist; A M Wolf; Herbert Tilg
The RANKL/OPG system is activated in inflammatory bowel disease and relates to the state of bone loss.
Gut 2005;54(4):479-87.
2005: Othmar Ludwiczek; Arthur Kaser; Daniela Novick; Charles A Dinarello; Menachem Rubinstein; Herbert Tilg
Elevated systemic levels of free interleukin-18 (IL-18) in patients with Crohn's disease.
European cytokine network 2005;16(1):27-33.
2005: Susanne Kaser; Alexander R Moschen; A Cayon; Arthur Kaser; J Crespo; F Pons-Romero; Christoph Ebenbichler; Josef R Patsch; Herbert Tilg
Adiponectin and its receptors in non-alcoholic steatohepatitis.
Gut 2005;54(1):117-21.
2005: Nicole Kaneider; Arthur Kaser; Stefan Dunzendorfer; Herbert Tilg; Josef R Patsch; Christian Wiedermann
Neurokinin-1 receptor interacts with PrP(106-126)-induced dendritic cell migration and maturation.
Journal of neuroimmunology 2005;158(1-2):153-8.
2004: Othmar Ludwiczek; Edouard Vannier; Ingo Borggraefe; Arthur Kaser; B Siegmund; Charles A Dinarello; Herbert Tilg
Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease.
Clinical and experimental immunology 2004;138(2):323-9.
2004: Clemens Molnar; Elena R Garcia-Trevijano; Othmar Ludwiczek; Dominique Talabot; Arthur Kaser; José M Mato; Gernot Fritsche; Günter Weiss; Cem Gabay; Matías A Avila; Herbert Tilg
Anti-inflammatory effects of hepatocyte growth factor: induction of interleukin-1 receptor antagonist.
European cytokine network 2004;15(4):303-11.
2004: Anna Maria Wolf; Dominik Wolf; Holger Rumpold; Alexander R Moschen; Arthur Kaser; Peter Obrist; Dietmar Fuchs; Gerald Brandacher; Christiane Winkler; Karel Geboes; Paul Rutgeerts; Herbert Tilg
Overexpression of indoleamine 2,3-dioxygenase in human inflammatory bowel disease.
Clinical immunology (Orlando, Fla.) 2004;113(1):47-55.
2004: Herbert Tilg; Arthur Kaser
Diet and relapsing ulcerative colitis: take off the meat?
Gut 2004;53(10):1399-401.
2004: Arthur Kaser; Susanne Kaser; Nicole Kaneider; Barbara Enrich; Christian Wiedermann; Herbert Tilg
Interleukin-18 attracts plasmacytoid dendritic cells (DC2s) and promotes Th1 induction by DC2s through IL-18 receptor expression.
Blood 2004;103(2):648-55.
2004: Arthur Kaser; Othmar Ludwiczek; Sandra Holzmann; Alexander R Moschen; Günter Weiss; Barbara Enrich; Ivo W Graziadei; Stefan Dunzendorfer; Christian Wiedermann; Elisabeth Mürzl; Eveline Grasl; Zerina Jasarevic; Nikolaus Romani; Felix Offner; Herbert Tilg
Increased expression of CCL20 in human inflammatory bowel disease.
Journal of clinical immunology 2004;24(1):74-85.
2003: Herbert Tilg; Harald Vogelsang; Othmar Ludwiczek; Herbert Lochs; Arthur Kaser; J-F Colombel; H Ulmer; Paul Rutgeerts; S Krüger; A Cortot; Geert D'Haens; Marieluise Harrer; Christoph Gasche; Fritz Wrba; I Kuhn; Walter Reinisch
A randomised placebo controlled trial of pegylated interferon alpha in active ulcerative colitis.
Gut 2003;52(12):1728-33.
2003: Susanne Kaser; Arthur Kaser; Anton Sandhofer; Christoph Ebenbichler; Herbert Tilg; Josef R Patsch
Resistin messenger-RNA expression is increased by proinflammatory cytokines in vitro.
Biochemical and biophysical research communications 2003;309(2):286-90.
2003: Nicole Kaneider; Arthur Kaser; Herbert Tilg; Giovanni Ricevuti; Christian Wiedermann
CD40 ligand-dependent maturation of human monocyte-derived dendritic cells by activated platelets.
International journal of immunopathology and pharmacology 2003;16(3):225-31.
2003: Nicole Kaneider; Arthur Kaser; Stefan Dunzendorfer; Herbert Tilg; Christian Wiedermann
Sphingosine kinase-dependent migration of immature dendritic cells in response to neurotoxic prion protein fragment.
Journal of virology 2003;77(9):5535-9.
2003: Herbert Tilg; Rajiv Jalan; Arthur Kaser; Nathan A Davies; Felix Offner; Stephen J Hodges; Othmar Ludwiczek; Debbie L Shawcross; Heinz Zoller; Akeel Alisa; Rajeshwar P Mookerjee; Ivo W Graziadei; Christian Datz; Michael Trauner; Detlef Schuppan; Peter Obrist; Wolfgang Vogel; Roger Williams
Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis.
Journal of hepatology 2003;38(4):419-25.
2003: Othmar Ludwiczek; Arthur Kaser; Herbert Tilg
Plasma levels of soluble CD40 ligand are elevated in inflammatory bowel diseases.
International journal of colorectal disease 2003;18(2):142-7.
2002: Heinz Zoller; Igor Theurl; Robert Koch; Arthur Kaser; Günter Weiss
Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1.
Blood cells, molecules & diseases 2002;29(3):488-97.
2002: Othmar Ludwiczek; Arthur Kaser; Daniela Novick; Charles A Dinarello; Menachem Rubinstein; Wolfgang Vogel; Herbert Tilg
Plasma levels of interleukin-18 and interleukin-18 binding protein are elevated in patients with chronic liver disease.
Journal of clinical immunology 2002;22(6):331-7.
2002: Arthur Kaser; Othmar Ludwiczek; Peter Waldenberger; Werner Jaschke; Wolfgang Vogel; Herbert Tilg
Endotoxin and its binding proteins in chronic liver disease: the effect of transjugular intrahepatic portosystemic shunting.
Liver 2002;22(5):380-7.
2002: Herbert Tilg; Arthur Kaser
Antitumour necrosis factor therapy in Crohn's disease.
Expert opinion on biological therapy 2002;2(7):715-21.
2002: Herbert Tilg; Hanno Ulmer; Arthur Kaser; Günter Weiss
Role of IL-10 for induction of anemia during inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):2204-9.
2002: Arthur Kaser; D Novick; M Rubinstein; B Siegmund; Barbara Enrich; Robert O Koch; Wolfgang Vogel; S H Kim; C A Dinarello; Herbert Tilg
Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients.
Clinical and experimental immunology 2002;129(2):332-8.
2002: Susanne Kaser; Arthur Kaser; Wolfgang Vogel; Josef R Patsch; Herbert Tilg
Interferon-alpha suppresses leptin levels: studies in interferon-alpha treated patients with hepatitis C virus infection and murine adipocytes.
European cytokine network 2002;13(2):225-9.
2002: Herbert Tilg; C van Montfrans; A van den Ende; Arthur Kaser; Sander J H van Deventer; S Schreiber; M Gregor; Othmar Ludwiczek; Paul Rutgeerts; Christoph Gasche; J C Koningsberger; L Abreu; I Kuhn; M Cohard; LeBeaut Pierre Alexandre; Paul C Grint; Günter Weiss
Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma.
Gut 2002;50(2):191-5.
2001: Arthur Kaser; Gerald Brandacher; W Steurer; Susanne Kaser; Felix Offner; Heinz Zoller; Igor Theurl; W Widder; Clemens Molnar; Othmar Ludwiczek; Michael B Atkins; J W Mier; Herbert Tilg
Interleukin-6 stimulates thrombopoiesis through thrombopoietin: role in inflammatory thrombocytosis.
Blood 2001;98(9):2720-5.
2001: Stefan Dunzendorfer; Nicole Kaneider; Arthur Kaser; E Woell; JM Frade; M Mellado; C Martínez-Alonso; Christian Wiedermann
Functional expression of chemokine receptor 2 by normal human eosinophils.
The Journal of allergy and clinical immunology 2001;108(4):581-7.
2001: Othmar Ludwiczek; Arthur Kaser; Robert O Koch; Wolfgang Vogel; WW Cruikshank; Herbert Tilg
Activation of caspase-3 by interferon alpha causes interleukin-16 secretion but fails to modulate activation induced cell death.
European cytokine network 2001;12(3):478-86.
2001: Patrizia Stoitzner; Gudrun Ratzinger; Franz Koch; Katrin Janke; T Schöller; Arthur Kaser; Herbert Tilg; W W Cruikshank; Peter Fritsch; Nikolaus Romani
Interleukin-16 supports the migration of Langerhans cells, partly in a CD4-independent way.
The Journal of investigative dermatology 2001;116(5):641-9.
2001: Stefan Dunzendorfer; Arthur Kaser; Christian Meierhofer; Herbert Tilg; Christian Wiedermann
Cutting edge: peripheral neuropeptides attract immature and arrest mature blood-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2167-72.
2000: Arthur Kaser; Stefan Dunzendorfer; Felix Offner; Othmar Ludwiczek; Barbara Enrich; Robert O Koch; WW Cruikshank; Christian Wiedermann; Herbert Tilg
B lymphocyte-derived IL-16 attracts dendritic cells and Th cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2474-80.
2000: Stefan Dunzendorfer; Arthur Kaser; Christian Meierhofer; Herbert Tilg; Christian Wiedermann
Dendritic cell migration in different micropore filter assays.
Immunology letters 2000;71(1):5-11.
1999: Arthur Kaser; Barbara Enrich; Othmar Ludwiczek; Wolfgang Vogel; Herbert Tilg
Interferon-alpha (IFN-alpha) enhances cytotoxicity in healthy volunteers and chronic hepatitis C infection mainly by the perforin pathway.
Clinical and experimental immunology 1999;118(1):71-7.
1999: H Tilg; Arthur Kaser
Interferons and their role In inflammation.
Current pharmaceutical design 1999;5(10):771-85.
1999: Arthur Kaser; S Nagata; Herbert Tilg
Interferon alpha augments activation-induced T cell death by upregulation of Fas (CD95/APO-1) and Fas ligand expression.
Cytokine 1999;11(10):736-43.
1999: Arthur Kaser; Stefan Dunzendorfer; Felix Offner; T Ryan; A Schwabegger; WW Cruikshank; Christian Wiedermann; Herbert Tilg
A role for IL-16 in the cross-talk between dendritic cells and T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3232-8.
1999: Arthur Kaser; W Vogel; Herbert Tilg
Plasma levels of soluble Fas during treatment of chronic hepatitis C patients with interferon alpha.
Journal of hepatology 1999;31(3):575.
1999: Arthur Kaser; Florian Deisenhammer; T Berger; Herbert Tilg
Interferon-beta 1b augments activation-induced T-cell death in multiple sclerosis patients.
Lancet 1999;353(9162):1413-4.
1999: Edouard Vannier; Arthur Kaser; Michael B Atkins; Giamila Fantuzzi; Charles A Dinarello; J W Mier; Herbert Tilg
Elevated circulating levels of soluble interleukin-1 receptor type II during interleukin-2 immunotherapy.
European cytokine network 1999;10(1):37-42.
1998: Herbert Tilg; Arthur Kaser
IL-6 and arthritis: a detrimental or beneficial mediator?
IDrugs : the investigational drugs journal 1998;1(8):890-5.
1998: Arthur Kaser; Clemens Molnar; Herbert Tilg
Differential regulation of interleukin 4 and interleukin 13 production by interferon alpha.
Cytokine 1998;10(2):75-81.