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Fatah Kashanchi

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Rachel Van Duyne; Chen Zeng; Hao Chen; Mahmoud H El Kouni; Irene Guendel; Elizabeth Jaworski; Zachary Klase; Dmytro Kovalskyy; Benjamin Lepene; Sergei Nekhai; Alexis Patanarut; David H Price; Gavin Sampey; Fatah Kashanchi
Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.
Myung-Chul Chung; Fatah Kashanchi; Aarthi Narayanan; Charles L Bailey; Taissia G Popova; Popov Serguei
Bacillus anthracis-derived nitric oxide induces protein S-nitrosylation contributing to macrophage death.
Zachary Klase; Gavin C Sampey; Fatah Kashanchi
Retrovirus infected cells contain viral microRNAs.

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All Publications

2013: Rachel Van Duyne; Chen Zeng; Hao Chen; Mahmoud H El Kouni; Irene Guendel; Elizabeth Jaworski; Zachary Klase; Dmytro Kovalskyy; Benjamin Lepene; Sergei Nekhai; Alexis Patanarut; David H Price; Gavin Sampey; Fatah Kashanchi
Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.
Journal of molecular biology 2013;425(4):812-29.
2013: Myung-Chul Chung; Fatah Kashanchi; Aarthi Narayanan; Charles L Bailey; Taissia G Popova; Popov Serguei
Bacillus anthracis-derived nitric oxide induces protein S-nitrosylation contributing to macrophage death.
Biochemical and biophysical research communications 2013;430(1):125-30.
2013: Zachary Klase; Gavin C Sampey; Fatah Kashanchi
Retrovirus infected cells contain viral microRNAs.
Retrovirology 2013;10():15.
2013: Jessica H Tonry; Charles Bailey; Calvin Carpenter; Ramin M Hakami; Fatah Kashanchi; Aarthi Narayanan; Popov Serguei; Myung-Chul Chung
In vivo murine and in vitro M-like cell models of gastrointestinal anthrax.
Microbes and infection / Institut Pasteur 2013;15(1):37-44.
2012: Aarthi Narayanan; Sergei Nekhai; Nassima Oumata; Jessica Roman; Gavin Sampey; Rachel Van Duyne; Massimo Caputi; Robert Currer; Hervé Galons; Irene Guendel; Benoît Joseph; Kylene Kehn-Hall; Laurent Meijer; Fatah Kashanchi
Use of ATP analogs to inhibit HIV-1 transcription.
Virology 2012;432(1):219-31.
2012: Wesley N Wayman; Hemraj B Dodiya; Xiu-Ti Hu; Fatah Kashanchi; Jeffrey H Kordower; Amanda L Persons; T Celeste Napier
Enduring cortical alterations after a single in-vivo treatment of HIV-1 Tat.
Neuroreport 2012;23(14):825-9.
2012: Aarthi Narayanan; Svetlana Senina; Michael Turell; Rachel Van Duyne; Kylene Kehn-Hall; Lindsay Lundberg; Alan Baer; Charles Bailey; Laura Bethel; Bhaskar Das; Ravi Das; Irene Guendel; Amy Lynn Hartman; Fatah Kashanchi
Curcumin inhibits Rift Valley fever virus replication in human cells.
The Journal of biological chemistry 2012;287(40):33198-214.
2012: Lisa J Henderson; Fatah Kashanchi; Srinivas D Narasipura; Vyacheslav Adarichev; Lena Al-Harthi
Identification of novel T cell factor 4 (TCF-4) binding sites on the HIV long terminal repeat which associate with TCF-4, β-catenin, and SMAR1 to repress HIV transcription.
Journal of virology 2012;86(17):9495-503.
2012: Jessica H Tonry; Charles L Bailey; Daniel S Chertow; Fatah Kashanchi; Kwang S Kim; Beth A McNichol; Serguei Popov; Nalini Ramarao; Olaf Schneewind; Scott Stibitz; Myung-Chul Chung
Bacillus anthracis protease InhA regulates BslA-mediated adhesion in human endothelial cells.
Cellular microbiology 2012;14(8):1219-30.
2012: Bindesh Shrestha; Prabhakar Sripadi; Callee M Walsh; Fatah Kashanchi; Kylene Kehn-Hall; Matthew J Powell; Trust T Razunguzwa; Akos Vertes
Rapid, non-targeted discovery of biochemical transformation and biomarker candidates in oncovirus-infected cell lines using LAESI mass spectrometry.
Chemical communications (Cambridge, England) 2012;48(31):3700-2.
2012: Larisa Dubrovsky; Irene Guendel; Fatah Kashanchi; Tatiana Pushkarsky; Svetlana Senina; Dmitri Sviridov; Rachel Van Duyne; Michael Bukrinsky
Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection.
Biochemical and biophysical research communications 2012;419(1):95-8.
2012: Alan Baer; Charles Bailey; Markus Kainulainen; Fatah Kashanchi; Aarthi Narayanan; Taissia Popova; Friedemann Weber; Dana Austin; Kylene Kehn-Hall
Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication.
The Journal of biological chemistry 2012;287(10):7399-410.
2012: Srinivas D Narasipura; Liang Chen; Sidney W Fu; Lisa J Henderson; Fatah Kashanchi; Lena Al-Harthi
Role of β-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes.
Journal of virology 2012;86(4):1911-21.
2012: Gavin C Sampey; Rachel Van Duyne; Robert Currer; Ravi Das; Aarthi Narayanan; Fatah Kashanchi
Complex role of microRNAs in HTLV-1 infections.
Frontiers in genetics 2012;3():295.
2012: Robert Currer; Ravi Das; Irene Guendel; Elizabeth Jaworski; Aarthi Narayanan; Gavin Sampey; Rachel Van Duyne; Fatah Kashanchi
HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways.
Frontiers in microbiology 2012;3():406.
2012: Denitra Breuer; Andrey V Ilatovskiy; Andrey Ivanov; Fatah Kashanchi; Alexander Kotelkin; Namita Kumari; Tatyana Ammosova; Monique Beullens; Mathieu Bollen; Michael G Petukhov; Philip R Roane; Sergei Nekhai
CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90.
Retrovirology 2012;9():94.
2012: Rachel Van Duyne; William Coley; Irene Guendel; Elizabeth Jaworski; Kylene Kehn-Hall; Zachary Klase; Renaud Mahieux; Aarthi Narayanan; Anastas Popratiloff; Jessica Roman; Fatah Kashanchi
Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery.
PloS one 2012;7(7):e40662.
2012: Dana Austin; Alan Baer; Charles Bailey; Fatah Kashanchi; Lindsay Lundberg; Aarthi Narayanan; Jean-Jacques Panthier; Taissia Popova; Annalise Schoonmaker; Nazly Shafagati; Kylene Kehn-Hall
p53 Activation following Rift Valley fever virus infection contributes to cell death and viral production.
PloS one 2012;7(5):e36327.
2012: Kylene Kehn-Hall; Lindsay Lundberg; Aarthi Narayanan; Chelsea Pinkham; Gavin Sampey; Kimberly L Schultz; Svetlana Senina; Eric Stavale; Rachel Van Duyne; M Javad Aman; Charles Bailey; Irene Guendel; Fatah Kashanchi
Modulation of GSK-3β activity in Venezuelan equine encephalitis virus infection.
PloS one 2012;7(4):e34761.
2012: Mudit Tyagi; Fatah Kashanchi
New and novel intrinsic host repressive factors against HIV-1: PAF1 complex, HERC5 and others.
Retrovirology 2012;9():19.
2011: Lena Al-Harthi; Fatah Kashanchi
Mechanisms of HIV-1 latency post HAART treatment area.
Current HIV research 2011;9(8):552-3.
2011: Rachel V Duyne; Kylene K-Hall; Aarthi Narayanan; Mohammed Saifuddin; Leonard Shultz; Fatah Kashanchi
Humanized mouse models of HIV-1 latency.
Current HIV research 2011;9(8):595-605.
2011: Rachel Van Duyne; Rebecca Easley; Edward Gregg; Irene Guendel; Kylene Kehn-Hall; Zachary Klase; Aarthi Narayanan; Sergei Nekhai; Nazly Shafagati; Mudit Tyagi; Fatah Kashanchi
Varying modulation of HIV-1 LTR activity by Baf complexes.
Journal of molecular biology 2011;411(3):581-96.
2011: Myung-Chul Chung; Shelley C Jorgensen; Fatah Kashanchi; Charles Bailey; Jessica H Tonry; Popov Serguei
Secreted Bacillus anthracis proteases target the host fibrinolytic system.
FEMS immunology and medical microbiology 2011;62(2):173-81.
2011: Kylene Kehn-Hall; Irene Guendel; Lawrence Carpio; Leandros Skaltsounis; Laurent Meijer; Lena Al-Harthi; Joseph P Steiner; Avindra Nath; Olaf Kutsch; Fatah Kashanchi
Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors.
Virology 2011;415(1):56-68.
2011: Serguei G Popov; Taissia G Popova; Fatah Kashanchi; Charles Bailey
Targeting the inflammasome and adenosine type-3 receptors improves outcome of antibiotic therapy in murine anthrax.
World journal of biological chemistry 2011;2(5):98-104.
2011: James L Atkins; Nikolai V Gorbunov; Valerie Trabosh; Rachel Van Duyne; Fatah Kashanchi; Andrei M Komarov
Ferrous iron is found in mesenteric lymph bound to TIMP-2 following hemorrhage/resuscitation.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2011;24(2):279-89.
2011: Aarthi Narayanan; Charles Bailey; Fatah Kashanchi; Kylene Kehn-Hall
Developments in antivirals against influenza, smallpox and hemorrhagic fever viruses.
Expert opinion on investigational drugs 2011;20(2):239-54.
2011: Aarthi Narayanan; Popov Serguei; Taissia Popova; Michael Turell; Charles Bailey; Jessica Chertow; Fatah Kashanchi; Jessica Kidd; Kylene Kehn-Hall
Alteration in superoxide dismutase 1 causes oxidative stress and p38 MAPK activation following RVFV infection.
PloS one 2011;6(5):e20354.
2011: Myung-Chul Chung; Jessica H Tonry; Aarthi Narayanan; Nathan P Manes; Ryan S Mackie; Bradford Gutting; Dhritiman V Mukherjee; Taissia G Popova; Fatah Kashanchi; Charles L Bailey; Popov Serguei
Bacillus anthracis interacts with plasmin(ogen) to evade C3b-dependent innate immunity.
PloS one 2011;6(3):e18119.
2011: Aarthi Narayanan; Kylene Kehn-Hall; Charles Bailey; Fatah Kashanchi
Analysis of the roles of HIV-derived microRNAs.
Expert opinion on biological therapy 2011;11(1):17-29.
2011: Zufan Debebe; Tatyana Ammosova; Denitra Breuer; David B Lovejoy; Danuta S Kalinowski; Krishna Kumar; Marina Jerebtsova; Patricio Ray; Fatah Kashanchi; Victor Roland Gordeuk; Des R Richardson; Sergei Nekhai
Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9.
Molecular pharmacology 2011;79(1):185-96.
2010: William Coley; Rachel Van Duyne; Lawrence Carpio; Irene Guendel; Kylene Kehn-Hall; Sebastien Chevalier; Aarthi Narayanan; Truong Luu; Norman Lee; Zachary Klase; Fatah Kashanchi
Absence of DICER in monocytes and its regulation by HIV-1.
The Journal of biological chemistry 2010;285(42):31930-43.
2010: Rebecca Easley; Lawrence Carpio; Luke Dannenberg; Soyun Choi; Dowser Alani; Rachel Van Duyne; Irene Guendel; Zachary Klase; Emmanuel Agbottah; Kylene Kehn-Hall; Fatah Kashanchi
Transcription through the HIV-1 nucleosomes: effects of the PBAF complex in Tat activated transcription.
Virology 2010;405(2):322-33.
2010: Matthew P Morrow; Angela Grant; Zahedi Mujawar; Larisa Dubrovsky; Tatiana Pushkarsky; Yana Kiselyeva; Lucas Jennelle; Nigora Mukhamedova; Alan T Remaley; Fatah Kashanchi; Dmitri Sviridov; Michael Bukrinsky
Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1.
Molecular pharmacology 2010;78(2):215-25.
2010: Rebecca Easley; Lawrence Carpio; Irene Guendel; Zachary Klase; Soyun Choi; Kylene Kehn-Hall; John N Brady; Fatah Kashanchi
Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes.
Journal of virology 2010;84(9):4755-68.
2010: Min Xu; Fatah Kashanchi; Altreisha Foster; Jamie Rotimi; Willie Turner; Victor Roland Gordeuk; Sergei Nekhai
Hepcidin induces HIV-1 transcription inhibited by ferroportin.
Retrovirology 2010;7():104.
2010: Taissia G Popova; Michael J Turell; Virginia Espina; Kylene Kehn-Hall; Jessica Kidd; Aarthi Narayanan; Lance Liotta; Emanuel F Petricoin; Fatah Kashanchi; Charles Bailey; Popov Serguei
Reverse-phase phosphoproteome analysis of signaling pathways induced by Rift valley fever virus in human small airway epithelial cells.
PloS one 2010;5(11):e13805.
2010: Lawrence Carpio; Zachary Klase; William Coley; Irene Guendel; Sarah Choi; Rachel Van Duyne; Aarthi Narayanan; Kylene Kehn-Hall; Laurent Meijer; Fatah Kashanchi
Erratum to: microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection.
Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research 2010;6(1):E386.
2010: Prabhakar Sripadi; Bindesh Shrestha; Rebecca L Easley; Lawrence Carpio; Kylene Kehn-Hall; Sebastien Chevalier; Renaud Mahieux; Fatah Kashanchi; Akos Vertes
Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry.
PloS one 2010;5(9):e12590.
2010: Lawrence Carpio; Zachary Klase; William Coley; Irene Guendel; Sarah Choi; Rachel Van Duyne; Aarthi Narayanan; Kylene Kehn-Hall; Laurent Meijer; Fatah Kashanchi
microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection.
Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research 2010;6(1):386-400.
2010: Irene Guendel; Lawrence Carpio; Caitlin Pedati; Arnold Schwartz; Christine Teal; Fatah Kashanchi; Kylene Kehn-Hall
Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function.
PloS one 2010;5(6):e11379.
2010: Rachel Van Duyne; Irene Guendel; Kylene Kehn-Hall; Rebecca Easley; Zachary Klase; Chenglong Liu; Mary Young; Fatah Kashanchi
The identification of unique serum proteins of HIV-1 latently infected long-term non-progressor patients.
AIDS research and therapy 2010;7():21.
2010: Irene Guendel; Emmanuel Agbottah; Kylene Kehn-Hall; Fatah Kashanchi
Inhibition of human immunodeficiency virus type-1 by cdk inhibitors.
AIDS research and therapy 2010;7(1):7.
2009: William Coley; Kylene Kehn-Hall; Rachel Van Duyne; Fatah Kashanchi
Novel HIV-1 therapeutics through targeting altered host cell pathways.
Expert opinion on biological therapy 2009;9(11):1369-82.
2009: Sharroya Charles; Tatyana Ammosova; Jessica Cardenas; Altreisha Foster; Jamie Rotimi; Marina Jerebtsova; Abisola A Ayodeji; Xiaomei Niu; Patricio E Ray; Victor Roland Gordeuk; Fatah Kashanchi; Sergei Nekhai
Regulation of HIV-1 transcription at 3% versus 21% oxygen concentration.
Journal of cellular physiology 2009;221(2):469-79.
2009: Rachel Van Duyne; Kylene Kehn-Hall; Lawrence Carpio; Fatah Kashanchi
Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case.
Expert review of proteomics 2009;6(5):515-26.
2009: Kylene Kehn-Hall; Fatah Kashanchi
Novel insights into transcriptional elongation: ubiquitination of HEXIM1 and p-TEFb activity.
Cell cycle (Georgetown, Tex.) 2009;8(16):2485.
2009: Rachel Van Duyne; Caitlin Pedati; Irene Guendel; Lawrence Carpio; Kylene Kehn-Hall; Mohammed Saifuddin; Fatah Kashanchi
The utilization of humanized mouse models for the study of human retroviral infections.
Retrovirology 2009;6():76.
2009: Irene Guendel; Lawrence Carpio; Rebecca Easley; Rachel Van Duyne; William Coley; Emmanuel Agbottah; Cynthia Dowd; Fatah Kashanchi; Kylene Kehn-Hall
9-Aminoacridine inhibition of HIV-1 Tat dependent transcription.
Virology journal 2009;6():114.
2009: Fatah Kashanchi; Kylene Kehn-Hall
Cyclin dependent kinases as attractive targets to prevent transcription from viral genomes.
Current pharmaceutical design 2009;15(21):2520-32.
2009: Zachary Klase; Rafael Winograd; Jeremiah Davis; Lawrence Carpio; Richard Hildreth; Mohammad Heydarian; Sidney Fu; Timothy McCaffrey; Eti Meiri; Mila Ayash-Rashkovsky; Shlomit Gilad; Zwi Bentwich; Fatah Kashanchi
HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression.
Retrovirology 2009;6():18.
2009: Meisheng Zhou; Keven Huang; Kyung-Jin Jung; Won-Kyung Cho; Zach Klase; Fatah Kashanchi; Cynthia A Pise-Masison; John N Brady
Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.
Journal of virology 2009;83(2):1036-44.
2008: Rachel Van Duyne; Jessica Cardenas; Rebecca Easley; Weilin Wu; Kylene Kehn-Hall; Zachary Klase; Susana Mendez; Chen Zeng; Hao Chen; Mohammed Saifuddin; Fatah Kashanchi
Effect of transcription peptide inhibitors on HIV-1 replication.
Virology 2008;376(2):308-22.
2008: Reem Berro; Caitlin Pedati; Kylene Kehn-Hall; Weilin Wu; Zachary Klase; Yasmine Even; Anne-Marie Genevière; Tatyana Ammosova; Sergei Nekhai; Fatah Kashanchi
CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing.
Journal of virology 2008;82(14):7155-66.
2008: Sébastien Alain Chevalier; Nga Ling Ko; Sara Calattini; Adeline Mallet; Marie-Christine Prévost; Kylene Kehn; John N Brady; Fatah Kashanchi; Antoine Gessain; Renaud Mahieux
Construction and characterization of a human T-cell lymphotropic virus type 3 infectious molecular clone.
Journal of virology 2008;82(13):6747-52.
2008: Rachel Van Duyne; Kylene Kehn-Hall; Zachary Klase; Rebecca Easley; Mohammad Heydarian; Mohammed Saifuddin; Weilin Wu; Fatah Kashanchi
Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication.
Expert review of proteomics 2008;5(3):507-28.
2008: Sebastian C Y Ku; Jialing Lee; Joanne Lau; Meera Gurumurthy; Raymond Ng; Siew Hui Lwa; Joseph Lee; Zachary Klase; Fatah Kashanchi; Sheng-Hao Chao
XBP-1, a novel human T-lymphotropic virus type 1 (HTLV-1) tax binding protein, activates HTLV-1 basal and tax-activated transcription.
Journal of virology 2008;82(9):4343-53.
2008: Peter D Burbelo; Elise Meoli; Hannah P Leahy; Jhanelle Graham; Yao Jiang Karen; Unsong Oh; John Janik; Renaud Mahieux; Fatah Kashanchi; Michael Iadarola; Steven Jacobson
Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Retrovirology 2008;5():96.
2008: Emmanuel Agbottah; Wen-I Yeh; Reem Berro; Zachary Klase; Caitlin Pedati; Kyleen Kehn-Hall; Weilin Wu; Fatah Kashanchi
Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways.
AIDS research and therapy 2008;5():12.
2008: Rachel Van Duyne; Rebecca Easley; Weilin Wu; Reem Berro; Caitlin Pedati; Zachary Klase; Kylene Kehn-Hall; Elizabeth K Flynn; David E Symer; Fatah Kashanchi
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR.
Retrovirology 2008;5():40.
2008: Weilin Wu; Kylene Kehn-Hall; Caitlin Pedati; Lynnsey Zweier; Iris Castro; Zachary Klase; Cynthia S Dowd; Larisa Dubrovsky; Michael Bukrinsky; Fatah Kashanchi
Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation.
Virology journal 2008;5():41.
2008: Zachary Klase; Rachel Van Duyne; Fatah Kashanchi
Identification of potential drug targets using genomics and proteomics: a systems approach.
Advances in pharmacology (San Diego, Calif.) 2008;56():327-68.
2007: Jialing Lee; Zachary Klase; Xiaoqi Gao; Jeremy S Caldwell; Mark F Stinski; Fatah Kashanchi; Sheng-Hao Chao
Cellular homeoproteins, SATB1 and CDP, bind to the unique region between the human cytomegalovirus UL127 and major immediate-early genes.
Virology 2007;366(1):117-25.
2007: Kylene Kehn; Reem Berro; A Alhaj; Maria Elena Bottazzi; W-I Yeh; Zachary Klase; R Van Duyne; S Fu; Fatah Kashanchi
Functional consequences of cyclin D1/BRCA1 interaction in breast cancer cells.
Oncogene 2007;26(35):5060-9.
2007: Deborah Carroll-Anzinger; Anvita Kumar; Vyacheslav Adarichev; Fatah Kashanchi; Lena Al-Harthi
Human immunodeficiency virus-restricted replication in astrocytes and the ability of gamma interferon to modulate this restriction are regulated by a downstream effector of the Wnt signaling pathway.
Journal of virology 2007;81(11):5864-71.
2007: Reem Berro; Cynthia de la Fuente; Zachary Klase; Kylene Kehn; Lida Parvin; Anne Pumfery; Emmanuel Agbottah; Akos Vertes; Sergei Nekhai; Fatah Kashanchi
Identifying the membrane proteome of HIV-1 latently infected cells.
The Journal of biological chemistry 2007;282(11):8207-18.
2007: Zachary Klase; Prachee Kale; Rafael Winograd; Madhur V Gupta; Mohammad Heydarian; Reem Berro; Timothy A McCaffrey; Fatah Kashanchi
HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR.
BMC molecular biology 2007;8():63.
2006: Yao Jiang Karen; Nahid Akyani; Donatella Donati; Naomi Sengamalay; Julie Fotheringham; Elodie Ghedin; Michael Bishop; John Barrett; Fatah Kashanchi; Steven Jacobson
Detection of HHV-6B in post-mortem central nervous system tissue of a post-bone marrow transplant recipient: a multi-virus array analysis.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2006;37 Suppl 1():S57-62.
2006: Yao Jiang Karen; Matthew Mandel; Nahid Akyani; Kristen Maynard; Naomi Sengamalay; Julie Fotheringham; Elodie Ghedin; Fatah Kashanchi; Steven Jacobson
Differential HHV-6A gene expression in T cells and primary human astrocytes based on multi-virus array analysis.
Glia 2006;53(8):789-98.
2006: Reem Berro; Kylene Kehn; Cynthia de la Fuente; Anne Pumfery; Richard Adair; John Wade; Anamaris M Colberg-Poley; John Hiscott; Fatah Kashanchi
Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32.
Journal of virology 2006;80(7):3189-204.
2006: Emmanuel Agbottah; Naigong Zhang; Shabnam Dadgar; Anne Pumfery; John D Wade; Chen Zeng; Fatah Kashanchi
Inhibition of HIV-1 virus replication using small soluble Tat peptides.
Virology 2006;345(2):373-89.
2006: Tatyana Ammosova; Reem Berro; Marina Jerebtsova; Angela Jackson; Sharroya Charles; Zachary Klase; William Southerland; Victor Roland Gordeuk; Fatah Kashanchi; Sergei Nekhai
Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription.
Retrovirology 2006;3():78.
2006: Anne Pumfery; Cynthia de la Fuente; Fatah Kashanchi
HTLV-1 Tax: centrosome amplification and cancer.
Retrovirology 2006;3():50.
2006: Emmanuel Agbottah; Longwen Deng; Luke O Dannenberg; Anne Pumfery; Fatah Kashanchi
Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription.
Retrovirology 2006;3():48.
2006: Cynthia de la Fuente; Madhur V Gupta; Zachary Klase; Katharine Strouss; Patrick Cahan; Timothy McCaffery; Anthony Galante; Patricia Soteropoulos; Anne Pumfery; Masahiro Fujii; Fatah Kashanchi
Involvement of HTLV-I Tax and CREB in aneuploidy: a bioinformatics approach.
Retrovirology 2006;3():43.
2006: Anne Pumfery; Cynthia de la Fuente; Reem Berro; Sergei Nekhai; Fatah Kashanchi; Sheng-Hao Chao
Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics.
Current pharmaceutical design 2006;12(16):1949-61.
2006: Sergey Iordanskiy; Reem Berro; Maria Altieri; Fatah Kashanchi; Michael Bukrinsky
Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatin.
Retrovirology 2006;3():4.
2005: Tatyana Ammosova; Marina Jerebtsova; Monique Beullens; Bart Lesage; Angela Jackson; Fatah Kashanchi; William Southerland; Victor Roland Gordeuk; Mathieu Bollen; Sergei Nekhai
Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein.
The Journal of biological chemistry 2005;280(43):36364-71.
2005: Tatyana Ammosova; Reem Berro; Fatah Kashanchi; Sergei Nekhai
RNA interference directed to CDK2 inhibits HIV-1 transcription.
Virology 2005;341(2):171-8.
2005: Omar Haffar; Larisa Dubrovsky; Richard Lowe; Reem Berro; Fatah Kashanchi; Jeffrey Godden; Christophe Vanpouille; Jürgen Bajorath; Michael Bukrinsky
Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein.
Journal of virology 2005;79(20):13028-36.
2005: Fatah Kashanchi; John N Brady
Transcriptional and post-transcriptional gene regulation of HTLV-1.
Oncogene 2005;24(39):5938-51.
2005: Emmanuel Agbottah; Cynthia de la Fuente; Sergei Nekhai; Anna Barnett; Athos Gianella-Borradori; Anne Pumfery; Fatah Kashanchi
Antiviral activity of CYC202 in HIV-1-infected cells.
The Journal of biological chemistry 2005;280(4):3029-42.
2005: Kylene Kehn; Cynthia de la Fuente; Katharine Strouss; Reem Berro; Hua Jiang; John Brady; Renaud Mahieux; Anne Pumfery; Maria Elena Bottazzi; Fatah Kashanchi
The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation.
Oncogene 2005;24(4):525-40.
2005: John Brady; Fatah Kashanchi
Tat gets the "green" light on transcription initiation.
Retrovirology 2005;2():69.
2005: Winnie S Liang; Anil Maddukuri; Tanya M Teslovich; Cynthia de la Fuente; Emmanuel Agbottah; Shabnam Dadgar; Kylene Kehn; Sampsa Hautaniemi; Anne Pumfery; Dietrich A Stephan; Fatah Kashanchi
Therapeutic targets for HIV-1 infection in the host proteome.
Retrovirology 2005;2():20.
2004: Meisheng Zhou; Longwen Deng; Vincent Lacoste; Hyeon Ung Park; Anne Pumfery; Fatah Kashanchi; John N Brady; Ajit Kumar
Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.
Journal of virology 2004;78(24):13522-33.
2004: Anila Seelamgari; Anil Maddukuri; Reem Berro; Cynthia de la Fuente; Kylene Kehn; Longwen Deng; Shabnam Dadgar; Maria Elena Bottazzi; Elodie Ghedin; Anne Pumfery; Fatah Kashanchi
Role of viral regulatory and accessory proteins in HIV-1 replication.
Frontiers in bioscience : a journal and virtual library 2004;9():2388-413.
2004: Kylene Kehn; Reem Berro; Cynthia de la Fuente; Katharine Strouss; Elodie Ghedin; Shabnam Dadgar; Maria Elena Bottazzi; Anne Pumfery; Fatah Kashanchi
Mechanisms of HTLV-1 transformation.
Frontiers in bioscience : a journal and virtual library 2004;9():2347-72.
2004: Vincent Lacoste; Cynthia de la Fuente; Fatah Kashanchi; Anne Pumfery
Kaposi's sarcoma-associated herpesvirus immediate early gene activity.
Frontiers in bioscience : a journal and virtual library 2004;9():2245-72.
2004: kaili wu; Maria Elena Bottazzi; Cynthia de la Fuente; Longwen Deng; Scott D Gitlin; Anil Maddukuri; Shabnam Dadgar; Hong Li; Akos Vertes; Anne Pumfery; Fatah Kashanchi
Protein profile of tax-associated complexes.
The Journal of biological chemistry 2004;279(1):495-508.
2004: Cynthia de la Fuente; Fatah Kashanchi
The expanding role of Tax in transcription.
Retrovirology 2004;1():19.
2004: Kylene Kehn; Longwen Deng; Cynthia de la Fuente; Katharine Strouss; kaili wu; Anil Maddukuri; Shanese Baylor; Robyn Rufner; Anne Pumfery; Maria Elena Bottazzi; Fatah Kashanchi
The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells.
Retrovirology 2004;1():6.
2004: Elodie Ghedin; Anne Pumfery; Cynthia de la Fuente; Karen Yao; Naomi Miller; Vincent Lacoste; John Quackenbush; Steven Jacobson; Fatah Kashanchi
Use of a multi-virus array for the study of human viral and retroviral pathogens: gene expression studies and ChIP-chip analysis.
Retrovirology 2004;1():10.
2003: Meisheng Zhou; Longwen Deng; Fatah Kashanchi; John N Brady; Aaron J Shatkin; Ajit Kumar
The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12666-71.
2003: Anne Pumfery; Longwen Deng; Anil Maddukuri; Cynthia de la Fuente; Hong Li; John D Wade; Paul Lambert; Ajit Kumar; Fatah Kashanchi
Chromatin remodeling and modification during HIV-1 Tat-activated transcription.
Current HIV research 2003;1(3):343-62.
2003: Cynthia de la Fuente; Anil Maddukuri; Kylene Kehn; Shanese Baylor; Longwen Deng; Anne Pumfery; Fatah Kashanchi
Pharmacological cyclin-dependent kinase inhibitors as HIV-1 antiviral therapeutics.
Current HIV research 2003;1(2):131-52.
2003: Cynthia de la Fuente; Lai Wang; Dai Wang; Longwen Deng; kaili wu; Hong Li; L Dana Stein; Thomas N Denny; Frederick Coffman; Kylene Kehn; Shanese Baylor; Anil Maddukuri; Anne Pumfery; Fatah Kashanchi
Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells.
Molecular and cellular biochemistry 2003;245(1-2):99-113.
2002: Longwen Deng; Tatyana Ammosova; Anne Pumfery; Fatah Kashanchi; Sergei Nekhai
HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter.
The Journal of biological chemistry 2002;277(37):33922-9.
2002: Lai Wang; Longwen Deng; kaili wu; Cynthia de la Fuente; Dai Wang; Kylene Kehn; Anil Maddukuri; Shanese Baylor; Francisco Santiago; Emmanuel Agbottah; Sylviane Trigon; Michel Morange; Renaud Mahieux; Fatah Kashanchi
Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors.
Molecular and cellular biochemistry 2002;237(1-2):137-53.
2002: Cynthia de la Fuente; Francisco Santiago; Longwen Deng; Carolyne Eadie; Irene Zilberman; Kylene Kehn; Anil Maddukuri; Shanese Baylor; kaili wu; Chee-Gun Lee; Anne Pumfery; Fatah Kashanchi
Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals.
BMC biochemistry 2002;3():14.
2002: Naoki Mori; Masahiro Fujii; Michael Hinz; Katsushi Nakayama; Yasuaki Yamada; Shuichi Ikeda; Yoshihiro Yamasaki; Fatah Kashanchi; Yuetsu Tanaka; Masao Tomonaga; Naoki Yamamoto
Activation of cyclin D1 and D2 promoters by human T-cell leukemia virus type I tax protein is associated with IL-2-independent growth of T cells.
International journal of cancer. Journal international du cancer 2002;99(3):378-85.
2002: Bansri Furia; Longwen Deng; kaili wu; Shanese Baylor; Kylene Kehn; Hong Li; Robert Donnelly; Tim Coleman; Fatah Kashanchi
Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins.
The Journal of biological chemistry 2002;277(7):4973-80.
2001: Longwen Deng; Dan Wang; Cynthia de la Fuente; Lihua Wang; Hong Li; Chee-Gun Lee; Robert Donnelly; John D Wade; Paul Lambert; Fatah Kashanchi
Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA.
Virology 2001;289(2):312-26.
2001: S Yen Chong; Yi-Chu Lin; JE Czarneski; M Zhang; Frederick Coffman; Fatah Kashanchi; Elizabeth Raveche
Cell cycle effects of IL-10 on malignant B-1 cells.
Genes and immunity 2001;2(5):239-47.
2001: D Wang; Cynthia de la Fuente; L Deng; L Wang; I Zilberman; C Eadie; M Healey; D Stein; Thomas N Denny; Lawrence E Harrison; L Meijer; Fatah Kashanchi
Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors.
Journal of virology 2001;75(16):7266-79.
2001: Renaud Mahieux; Paul F Lambert; Emmanuel Agbottah; M A Halanski; Longwen Deng; Fatah Kashanchi; John N Brady
Cell cycle regulation of human interleukin-8 gene expression by the human immunodeficiency virus type 1 Tat protein.
Journal of virology 2001;75(4):1736-43.
2000: Longwen Deng; Cynthia de la Fuente; P Fu; Lihua Wang; Robert Donnelly; John D Wade; Paul Lambert; Hong Li; Chee-Gun Lee; Fatah Kashanchi
Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones.
Virology 2000;277(2):278-95.
2000: Cynthia de la Fuente; Longwen Deng; Francisco Santiago; L Arce; Lihua Wang; Fatah Kashanchi
Gene expression array of HTLV type 1-infected T cells: Up-regulation of transcription factors and cell cycle genes.
AIDS research and human retroviruses 2000;16(16):1695-700.
2000: T Mayhood; Neerja Kaushik; Pradeep K Pandey; Fatah Kashanchi; Longwen Deng; Virendra N Pandey
Inhibition of Tat-mediated transactivation of HIV-1 LTR transcription by polyamide nucleic acid targeted to TAR hairpin element.
Biochemistry 2000;39(38):11532-9.
2000: Amel Ahmed; DUANE SMOOT; G Littleton; Robert Tackey; Curla S Walters; Fatah Kashanchi; Cornell R Allen; Hassan Ashktorab
Helicobacter pylori inhibits gastric cell cycle progression.
Microbes and infection / Institut Pasteur 2000;2(10):1159-69.
2000: Cynthia de la Fuente; Francisco Santiago; SY Chong; Longwen Deng; T Mayhood; P Fu; D Stein; Thomas N Denny; Frederick Coffman; N Azimi; Renaud Mahieux; Fatah Kashanchi
Overexpression of p21(waf1) in human T-cell lymphotropic virus type 1-infected cells and its association with cyclin A/cdk2.
Journal of virology 2000;74(16):7270-83.
2000: QM Wang; Rena Feinman; Fatah Kashanchi; JM Houghton; George P Studzinski; Lawrence E Harrison
Changes in E2F binding after phenylbutyrate-induced differentiation of Caco-2 colon cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2951-8.
2000: Ming Zhou; M A Halanski; Michael F Radonovich; Fatah Kashanchi; Junmin Peng; D H Price; John N Brady
Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription.
Molecular and cellular biology 2000;20(14):5077-86.
2000: E Clark; Francisco Santiago; Longwen Deng; S Chong; Cynthia de la Fuente; Lihua Wang; P Fu; D Stein; Thomas N Denny; V Lanka; F Mozafari; T Okamoto; Fatah Kashanchi
Loss of G(1)/S checkpoint in human immunodeficiency virus type 1-infected cells is associated with a lack of cyclin-dependent kinase inhibitor p21/Waf1.
Journal of virology 2000;74(11):5040-52.
2000: Ming Zhou; Fatah Kashanchi; H Jiang; H Ge; John N Brady
Phosphorylation of the RAP74 subunit of TFIIF correlates with Tat-activated transcription of the HIV-1 long terminal repeat.
Virology 2000;268(2):452-60.
2000: Fatah Kashanchi; Emmanuel Agbottah; Cynthia A Pise-Masison; Renaud Mahieux; Janet Duvall; Ajit Kumar; John N Brady
Cell cycle-regulated transcription by the human immunodeficiency virus type 1 Tat transactivator.
Journal of virology 2000;74(2):652-60.
1999: Francisco Santiago; E Clark; S Chong; C Molina; F Mozafari; Renaud Mahieux; M Fujii; N Azimi; Fatah Kashanchi
Transcriptional up-regulation of the cyclin D2 gene and acquisition of new cyclin-dependent kinase partners in human T-cell leukemia virus type 1-infected cells.
Journal of virology 1999;73(12):9917-27.
1998: Fatah Kashanchi; Janet Duvall; Roland P S Kwok; James R Lundblad; Richard H Goodman; John N Brady
The coactivator CBP stimulates human T-cell lymphotrophic virus type I Tax transactivation in vitro.
The Journal of biological chemistry 1998;273(51):34646-52.
1998: Paul F Lambert; Fatah Kashanchi; Michael F Radonovich; Ramin Shiekhattar; John N Brady
Phosphorylation of p53 serine 15 increases interaction with CBP.
The Journal of biological chemistry 1998;273(49):33048-53.
1997: Fatah Kashanchi; J C Melpolder; Jay S Epstein; M Reza Sadaie
Rapid and sensitive detection of cell-associated HIV-1 in latently infected cell lines and in patient cells using sodium-n-butyrate induction and RT-PCR.
Journal of medical virology 1997;52(2):179-89.
1997: Fatah Kashanchi; J Araujo; Jay Doniger; Sumitra Muralidhar; R Hoch; Samir N Khleif; E Mendelson; J Thompson; N Azumi; John N Brady; M Luppi; G Torelli; Leonard J Rosenthal
Human herpesvirus 6 (HHV-6) ORF-1 transactivating gene exhibits malignant transforming activity and its protein binds to p53.
Oncogene 1997;14(3):359-67.
1997: Fatah Kashanchi; M Reza Sadaie; John N Brady
Inhibition of HIV-1 transcription and virus replication using soluble Tat peptide analogs.
Virology 1997;227(2):431-8.
1996: Sumitra Muralidhar; Jay Doniger; E Mendelson; J C Araujo; Fatah Kashanchi; N Azumi; John N Brady; Leonard J Rosenthal
Human cytomegalovirus mtrII oncoprotein binds to p53 and down-regulates p53-activated transcription.
Journal of virology 1996;70(12):8691-700.
1996: Fatah Kashanchi; Samir N Khleif; J F Duvall; M Reza Sadaie; Michael F Radonovich; M Cho; Malcolm Martin; S Y Chen; roberto weinmann; John N Brady
Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex.
Journal of virology 1996;70(8):5503-10.
1996: A Mireskandari; R L Reid; Fatah Kashanchi; Jürgen Dittmer; W B Li; John N Brady
Isolation of a cDNA clone, TRX encoding a human T-cell lymphotrophic virus type-I Tax1 binding protein.
Biochimica et biophysica acta 1996;1306(1):9-13.
1996: L Zhang; Fatah Kashanchi; Qimin Zhan; S Zhan; John N Brady; Albert J Fornace; Pankaj Seth; Lee Helman
Regulation of insulin-like growth factor II P3 promotor by p53: a potential mechanism for tumorigenesis.
Cancer research 1996;56(6):1367-73.
1995: J F Duvall; Fatah Kashanchi; Ales Cvekl; Michael F Radonovich; G Piras; John N Brady
Transactivation of the human T-cell lymphotropic virus type 1 Tax1-responsive 21-base-pair repeats requires Holo-TFIID and TFIIA.
Journal of virology 1995;69(8):5077-86.
1995: J C Araujo; Jay Doniger; Fatah Kashanchi; P L Hermonat; J Thompson; Leonard J Rosenthal
Human herpesvirus 6A ts suppresses both transformation by H-ras and transcription by the H-ras and human immunodeficiency virus type 1 promoters.
Journal of virology 1995;69(8):4933-40.
1995: T Kevin Howcroft; L A Palmer; J Brown; Barbara L Rellahan; Fatah Kashanchi; John N Brady; dinah singer
HIV Tat represses transcription through Sp1-like elements in the basal promoter.
Immunity 1995;3(1):127-38.
1995: Ales Cvekl; Fatah Kashanchi; CM Sax; John N Brady; Joram Piatigorsky
Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site.
Molecular and cellular biology 1995;15(2):653-60.
1994: G Piras; Fatah Kashanchi; Michael F Radonovich; J F Duvall; John N Brady
Transcription of the human T-cell lymphotropic virus type I promoter by an alpha-amanitin-resistant polymerase.
Journal of virology 1994;68(10):6170-9.
1994: J. Paul Taylor; Roger J Pomerantz; Ganesh V Raj; Fatah Kashanchi; John N Brady; Shohreh Amini; Kamel Khalili
Central nervous system-derived cells express a kappa B-binding activity that enhances human immunodeficiency virus type 1 transcription in vitro and facilitates TAR-independent transactivation by Tat.
Journal of virology 1994;68(6):3971-81.
1994: Fatah Kashanchi; J Thompson; M Reza Sadaie; Jay Doniger; J Duvall; John N Brady; Leonard J Rosenthal
Transcriptional activation of minimal HIV-1 promoter by ORF-1 protein expressed from the SalI-L fragment of human herpesvirus 6.
Virology 1994;201(1):95-106.
1994: Fatah Kashanchi; R Shibata; E K Ross; John N Brady; Malcolm Martin
Second-site long terminal repeat (LTR) revertants of replication-defective human immunodeficiency virus: effects of revertant TATA box motifs on virus infectivity, LTR-directed expression, in vitro RNA synthesis, and binding of basal transcription factors TFIID and TFIIA.
Journal of virology 1994;68(5):3298-307.
1994: J Thompson; S Choudhury; Fatah Kashanchi; Jay Doniger; Z Berneman; N Frenkel; Leonard J Rosenthal
A transforming fragment within the direct repeat region of human herpesvirus type 6 that transactivates HIV-1.
Oncogene 1994;9(4):1167-75.
1994: Fatah Kashanchi; G Piras; Michael F Radonovich; J F Duvall; A Fattaey; Cheng-Ming Chiang; R G Roeder; John N Brady
Direct interaction of human TFIID with the HIV-1 transactivator tat.
Nature 1994;367(6460):295-9.
1994: Fatah Kashanchi; J F Duvall; Jürgen Dittmer; A Mireskandari; R L Reid; Scott D Gitlin; John N Brady
Involvement of transcription factor YB-1 in human T-cell lymphotropic virus type I basal gene expression.
Journal of virology 1994;68(1):561-5.
1993: K A Gutekunst; Fatah Kashanchi; John N Brady; D P Bednarik
Transcription of the HIV-1 LTR is regulated by the density of DNA CpG methylation.
Journal of acquired immune deficiency syndromes 1993;6(6):541-9.
1993: Fatah Kashanchi; J F Duvall; P F Lindholm; Michael F Radonovich; John N Brady
Sequences downstream of the RNA initiation site regulate human T-cell lymphotropic virus type I basal gene expression.
Journal of virology 1993;67(5):2894-902.
1992: Fatah Kashanchi; J F Duvall; John N Brady
Electroporation of viral transactivator proteins into lymphocyte suspension cells.
Nucleic acids research 1992;20(17):4673-4.
1992: A Inamdar; J Thompson; Fatah Kashanchi; Jay Doniger; John N Brady; Leonard J Rosenthal
Identification of two promoters within human cytomegalovirus morphologic transforming region II.
Intervirology 1992;34(3):146-53.
1992: C A Bohan; Fatah Kashanchi; Barbara Ensoli; Luigi Buonaguro; K A Boris-Lawrie; John N Brady
Analysis of Tat transactivation of human immunodeficiency virus transcription in vitro.
Gene expression 1992;2(4):391-407.