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Hiromu Kashida

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Tomohiro Kato; Hideo Kishida; Hiroshi Okamoto; Hiroyuki Yada; Hiromu Kashida; Hiroyuki Asanuma
Development of a robust model system of FRET using base surrogates tethering fluorophores for strict control of their position and orientation within DNA duplex.
Taiga Fujii; Hiroshi Ito; Hiromu Kashida; Koichi Kato; Xingguo Liang; Masaaki Urushihara; Maho Yagi-Utsumi; Hiroyuki Asanuma
Reversed assembly of dyes in an RNA duplex compared with those in DNA.
Taiga Fujii; Yuichi Hara; Hiromu Kashida; Xingguo Liang; Takuya Osawa; Yasuko Yoshida; Hiroyuki Asanuma
Bulge-like asymmetric heterodye clustering in DNA duplex results in efficient quenching of background emission based on the maximized excitonic interaction.

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All Publications

2013: Tomohiro Kato; Hideo Kishida; Hiroshi Okamoto; Hiroyuki Yada; Hiromu Kashida; Hiroyuki Asanuma
Development of a robust model system of FRET using base surrogates tethering fluorophores for strict control of their position and orientation within DNA duplex.
Journal of the American Chemical Society 2013;135(2):741-50.
2012: Taiga Fujii; Hiroshi Ito; Hiromu Kashida; Koichi Kato; Xingguo Liang; Masaaki Urushihara; Maho Yagi-Utsumi; Hiroyuki Asanuma
Reversed assembly of dyes in an RNA duplex compared with those in DNA.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(42):13304-13.
2012: Taiga Fujii; Yuichi Hara; Hiromu Kashida; Xingguo Liang; Takuya Osawa; Yasuko Yoshida; Hiroyuki Asanuma
Bulge-like asymmetric heterodye clustering in DNA duplex results in efficient quenching of background emission based on the maximized excitonic interaction.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(35):10865-72.
2012: Hiromu Kashida; Kyohei Yamaguchi; Yuichi Hara; Hiroyuki Asanuma
Quencher-free molecular beacon tethering 7-hydroxycoumarin detects targets through protonation/deprotonation.
Bioorganic & medicinal chemistry 2012;20(14):4310-5.
2012: Hiromu Kashida; Hiroyuki Asanuma
Preparation of supramolecular chromophoric assemblies using a DNA duplex.
Physical chemistry chemical physics : PCCP 2012;14(20):7196-204.
2011: Hiromu Kashida; Tomohiro Kato; Koji Sekiguchi; Naofumi Higashiyama; Hiroyuki Asanuma
Cyclohexyl "base pairs" stabilize duplexes and intensify pyrene fluorescence by shielding it from natural base pairs.
Organic & biomolecular chemistry 2011;9(24):8313-20.
2011: Hiromu Kashida; Nobuyo Kondo; Koji Sekiguchi; Hiroyuki Asanuma
Detection of three-base deletion by exciplex formation with perylene derivatives.
Chemical communications (Cambridge, England) 2011;47(22):6404-6.
2011: Hiromu Kashida; Takamitsu Hayashi; Taiga Fujii; Hiroyuki Asanuma
A cationic dye triplet as a unique "glue" that can connect fully matched termini of DNA duplexes.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(9):2614-22.
2011: Hiromu Kashida; Keiji Murayama; Takasuke Toda; Hiroyuki Asanuma
Control of the chirality and helicity of oligomers of serinol nucleic acid (SNA) by sequence design.
Angewandte Chemie (International ed. in English) 2011;50(6):1285-8.
2010: Hiroyuki Asanuma; Takasuke Toda; Keiji Murayama; Xingguo Liang; Hiromu Kashida
Unexpectedly stable artificial duplex from flexible acyclic threoninol.
Journal of the American Chemical Society 2010;132(42):14702-3.
2010: Hiromu Kashida; Koji Sekiguchi; Hiroyuki Asanuma
Insulator base pairs for lighting-up perylenediimide in a DNA duplex.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(38):11554-7.
2010: Yuichi Hara; Taiga Fujii; Hiromu Kashida; Koji Sekiguchi; Xingguo Liang; Kosuke Niwa; Tomokazu Takase; Yasuko Yoshida; Hiroyuki Asanuma
Coherent quenching of a fluorophore for the design of a highly sensitive in-stem molecular beacon.
Angewandte Chemie (International ed. in English) 2010;49(32):5502-6.
2010: Hiromu Kashida; Koji Sekiguchi; Xingguo Liang; Hiroyuki Asanuma
Accumulation of fluorophores into DNA duplexes to mimic the properties of quantum dots.
Journal of the American Chemical Society 2010;132(17):6223-30.
2010: Hiromu Kashida; Tomohiko Takatsu; Koji Sekiguchi; Hiroyuki Asanuma
An efficient fluorescence resonance energy transfer (FRET) between pyrene and perylene assembled in a DNA duplex and its potential for discriminating single-base changes.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(8):2479-86.
2009: Taiga Fujii; Hiromu Kashida; Hiroyuki Asanuma
Analysis of coherent heteroclustering of different dyes by use of threoninol nucleotides for comparison with the molecular exciton theory.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(39):10092-102.
2009: Hiromu Kashida; Hidehiro Ito; Taiga Fujii; Takamitsu Hayashi; Hiroyuki Asanuma
Positively charged base surrogate for highly stable "base pairing" through electrostatic and stacking interactions.
Journal of the American Chemical Society 2009;131(29):9928-30.
2009: Hiromu Kashida; Kanae Sano; Yuichi Hara; Hiroyuki Asanuma
Modulation of pK(a) of Brooker's merocyanine by DNA hybridization.
Bioconjugate chemistry 2009;20(2):258-65.
2009: Hiromu Kashida; Tomohiko Takatsu; Hiroyuki Asanuma
Efficient energy transfer from pyrene to perylene assembled inside DNA duplex.
Nucleic acids symposium series (2004) 2009;(53):29-30.
2009: Hiromu Kashida; Tomohiko Takatsu; Taiga Fujii; Koji Sekiguchi; Xingguo Liang; Kosuke Niwa; Tomokazu Takase; Yasuko Yoshida; Hiroyuki Asanuma
In-stem molecular beacon containing a pseudo base pair of threoninol nucleotides for the removal of background emission.
Angewandte Chemie (International ed. in English) 2009;48(38):7044-7.
2008: Hiromu Kashida; Taiga Fujii; Hiroyuki Asanuma
Threoninol as a scaffold of dyes (threoninol-nucleotide) and their stable interstrand clustering in duplexes.
Organic & biomolecular chemistry 2008;6(16):2892-9.
2008: Hiromu Kashida; Hidehiro Itoh; Taiga Fujii; Hiroyuki Asanuma
Incorporation of cationic dyes into DNA for distinct stabilization of duplex.
Nucleic acids symposium series (2004) 2008;(52):701-2.
2008: Taiga Fujii; Hiromu Kashida; Hiroyuki Asanuma
Preparation of coherent hetero clusters with threoninol scaffold.
Nucleic acids symposium series (2004) 2008;(52):699-700.
2007: Hidenori Nishioka; Xingguo Liang; Hiromu Kashida; Hiroyuki Asanuma
2',6'-Dimethylazobenzene as an efficient and thermo-stable photo-regulator for the photoregulation of DNA hybridization.
Chemical communications (Cambridge, England) 2007;(42):4354-6.
2007: Hiromu Kashida; Tomohiko Takatsu; Hiroyuki Asanuma
Development of high-sensitive DNA probe by using perylene.
Nucleic acids symposium series (2004) 2007;(51):279-80.
2007: Taiga Fujii; Hiromu Kashida; Hiroyuki Asanuma
Preparation of "comb-type" hetero aggregates by DNA-dye conjugation.
Nucleic acids symposium series (2004) 2007;(51):277-8.
2007: Hiromu Kashida; Taiga Fujii; Hiroyuki Asanuma
Construction of novel dye aggregates based on "comb-type" sequence.
Nucleic acids symposium series (2004) 2007;(51):11-2.
2006: Hiroyuki Asanuma; Hiroyuki Hayashi; Jing Zhao; Xingguo Liang; Akira Yamazawa; Takeshi Kuramochi; Daijiro Matsunaga; Yuichiro Aiba; Hiromu Kashida; Makoto Komiyama
Enhancement of RNA cleavage activity of 10-23 DNAzyme by covalently introduced intercalator.
Chemical communications (Cambridge, England) 2006;(48):5062-4.
2006: Hidenori Nishioka; Hiromu Kashida; Makoto Komiyama; Xingguo Liang; Hiroyuki Asanuma
Incorporation of methyl group on azobenzene for the effective photo-regulation of hybridization and suppression of thermal isomerization.
Nucleic acids symposium series (2004) 2006;(50):85-6.