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Wolfgang Baehr

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Chemicals & Drugs

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Molecular Sequence Data

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Genes & Molecular Sequences

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Retinal Degeneration

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Sanford L Boye; Alexander M Dizhoor; Frank M Dyka; Thomas C Foster; William W Hauswirth; Wei Chieh Huang; Samuel G Jacobson; Sukanya Karan; Christine N Kay; Xuan Liu; Issam McDoom; Seok-Hong Min; Igor V Peshenko; Yumiko Umino; Wolfgang Baehr; Shannon E Boye
AAV-mediated gene therapy in the guanylate cyclase (RetGC1/RetGC2) double knockout mouse model of Leber congenital amaurosis.
Li Jiang; Tansy Z Li; Shannon E Boye; Jeanne M Frederick; William W Hauswirth; Wolfgang Baehr
RNAi-mediated gene suppression in a GCAP1(L151F) cone-rod dystrophy mouse model.
Ryan Constantine; Jeanne M Frederick; Cecilia D Gerstner; Houbin Zhang; Wolfgang Baehr
Uncoordinated (UNC)119: coordinating the trafficking of myristoylated proteins.

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2013: Sanford L Boye; Alexander M Dizhoor; Frank M Dyka; Thomas C Foster; William W Hauswirth; Wei Chieh Huang; Samuel G Jacobson; Sukanya Karan; Christine N Kay; Xuan Liu; Issam McDoom; Seok-Hong Min; Igor V Peshenko; Yumiko Umino; Wolfgang Baehr; Shannon E Boye
AAV-mediated gene therapy in the guanylate cyclase (RetGC1/RetGC2) double knockout mouse model of Leber congenital amaurosis.
Human gene therapy 2013;24(2):189-202.
2013: Li Jiang; Tansy Z Li; Shannon E Boye; Jeanne M Frederick; William W Hauswirth; Wolfgang Baehr
RNAi-mediated gene suppression in a GCAP1(L151F) cone-rod dystrophy mouse model.
PloS one 2013;8(3):e57676.
2012: Ryan Constantine; Jeanne M Frederick; Cecilia D Gerstner; Houbin Zhang; Wolfgang Baehr
Uncoordinated (UNC)119: coordinating the trafficking of myristoylated proteins.
Vision research 2012;75():26-32.
2012: Houbin Zhang; Ryan Constantine; Jeanne M Frederick; Wolfgang Baehr
The prenyl-binding protein PrBP/δ: a chaperone participating in intracellular trafficking.
Vision research 2012;75():19-25.
2012: C C Ronquillo; Paul S Bernstein; Wolfgang Baehr
Senior-Løken syndrome: a syndromic form of retinal dystrophy associated with nephronophthisis.
Vision research 2012;75():88-97.
2011: Li Jiang; Houbin Zhang; Shannon E Boye; Alexander M Dizhoor; Jeanne M Frederick; William W Hauswirth; Wolfgang Baehr
Long-term RNA interference gene therapy in a dominant retinitis pigmentosa mouse model.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(45):18476-81.
2011: Sukanya Karan; Orson L Moritz; Beatrice M Tam; Wolfgang Baehr
Targeting of mouse guanylate cyclase 1 (Gucy2e) to Xenopus laevis rod outer segments.
Vision research 2011;51(21-22):2304-11.
2011: Houbin Zhang; Yang Chen; Ryan Constantine; M Wayne Davis; Cecilia D Gerstner; Christopher P Hill; Yuanpeng Janet Huang; George Inana; Erik M Jorgensen; Gaetano T Montelione; Jayaraman Seetharaman; Liang Tong; Sergey Vorobiev; Frank G Whitby; Rong Xiao; Wolfgang Baehr
UNC119 is required for G protein trafficking in sensory neurons.
Nature neuroscience 2011;14(7):874-80.
2011: Tao Zhang; Ning Zhang; Wolfgang Baehr; Yingbin Fu
Cone opsin determines the time course of cone photoreceptor degeneration in Leber congenital amaurosis.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):8879-84.
2011: Wolfgang Baehr; Ted Wensel; Greg Hageman; Sam Wu; Donald J Zack
Retinal ganglion cells: development, function, and disease.
Vision research 2011;51(2):223.
2011: Félix R Vázquez-Chona; Robert E Marc; Alex Swan; Wolfgang Baehr; Wei-Ming Chien; Matthew Fero; W Drew Ferrell; Li Jiang; Edward M Levine
Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function.
BMC neuroscience 2011;12():98.
2010: Li Jiang; Wolfgang Baehr
GCAP1 mutations associated with autosomal dominant cone dystrophy.
Advances in experimental medicine and biology 2010;664():273-82.
2010: Sukanya Karan; Jeanne M Frederick; Wolfgang Baehr
Novel functions of photoreceptor guanylate cyclases revealed by targeted deletion.
Molecular and cellular biochemistry 2010;334(1-2):141-55.
2009: Prachee Avasthi; Carl B Watt; David S Williams; Yun Z Le; Sha Li; Ching-Kang Chen; Robert E Marc; Jeanne M Frederick; Wolfgang Baehr
Trafficking of membrane proteins to cone but not rod outer segments is dependent on heterotrimeric kinesin-II.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(45):14287-98.
2009: Wolfgang Baehr; Jeanne M Frederick
Naturally occurring animal models with outer retina phenotypes.
Vision research 2009;49(22):2636-52.
2009: Wolfgang Baehr; Krzysztof Palczewski
Focus on molecules: guanylate cyclase-activating proteins (GCAPs).
Experimental eye research 2009;89(1):2-3.
2008: Li Jiang; Dianna Wheaton; Grzegorz Bereta; Kang Zhang; Krzysztof Palczewski; David G Birch; Wolfgang Baehr
A novel GCAP1(N104K) mutation in EF-hand 3 (EF3) linked to autosomal dominant cone dystrophy.
Vision research 2008;48(23-24):2425-32.
2008: Jie Fan; Baerbel Rohrer; Jeanne M Frederick; Wolfgang Baehr; Rosalie K Crouch
Rpe65-/- and Lrat-/- mice: comparable models of leber congenital amaurosis.
Investigative ophthalmology & visual science 2008;49(6):2384-9.
2008: Houbin Zhang; Jie Fan; Sha Li; Sukanya Karan; Baerbel Rohrer; Krzysztof Palczewski; Jeanne M Frederick; Rosalie K Crouch; Wolfgang Baehr
Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(15):4008-14.
2008: Sukanya Karan; Houbin Zhang; Sha Li; Jeanne M Frederick; Wolfgang Baehr
A model for transport of membrane-associated phototransduction polypeptides in rod and cone photoreceptor inner segments.
Vision research 2008;48(3):442-52.
2008: Sukanya Karan; Jeanne M Frederick; Wolfgang Baehr
Involvement of guanylate cyclases in transport of photoreceptor peripheral membrane proteins.
Advances in experimental medicine and biology 2008;613():351-9.
2007: Haikun Zhang; Sha Li; T Doan; Fred Rieke; Peter B Detwiler; Jeanne M Frederick; Wolfgang Baehr
Deletion of PrBP/delta impedes transport of GRK1 and PDE6 catalytic subunits to photoreceptor outer segments.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):8857-62.
2007: Wolfgang Baehr; Sukanya Karan; Tadao Maeda; Donggen Luo; Sha Li; J Darin Bronson; Carl B Watt; King-Wai Yau; Jeanne M Frederick; Krzysztof Palczewski
The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors.
The Journal of biological chemistry 2007;282(12):8837-47.
2007: Wolfgang Baehr; Krzysztof Palczewski
Guanylate cyclase-activating proteins and retina disease.
Sub-cellular biochemistry 2007;45():71-91.
2006: Houbin Zhang; Jeanne M Frederick; Wolfgang Baehr
Functional study of photoreceptor PDEdelta.
Advances in experimental medicine and biology 2006;572():485-90.
2005: Matthew L Batten; Yoshikazu Imanishi; Daniel C Tu; Thuy Doan; Li Zhu; Jijing Pang; Lyudmila Glushakova; Alexander R Moise; Wolfgang Baehr; Russell N Van Gelder; William W Hauswirth; Fred Rieke; Krzysztof Palczewski
Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis.
PLoS medicine 2005;2(11):e333.
2005: Alexander R Moise; Vladimir Kuksa; William S Blaner; Wolfgang Baehr; Krzysztof Palczewski
Metabolism and transactivation activity of 13,14-dihydroretinoic acid.
The Journal of biological chemistry 2005;280(30):27815-25.
2005: Akiko Maeda; Tadao Maeda; Yoshikazu Imanishi; Vladimir Kuksa; Andrei Alekseev; J Darin Bronson; Houbin Zhang; Li Zhu; Wenyu Sun; David A Saperstein; Fred Rieke; Wolfgang Baehr; Krzysztof Palczewski
Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.
The Journal of biological chemistry 2005;280(19):18822-32.
2005: Izabela Sokal; William Dupps; Michael Grassi; Jeremiah Brown; Louisa M Affatigato; Nirmalya Roychowdhury; Lili Yang; Slawomir Filipek; Krzysztof Palczewski; Edwin M Stone; Wolfgang Baehr
A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD).
Investigative ophthalmology & visual science 2005;46(4):1124-32.
2005: Li Jiang; Bradley J Katz; Zhenglin Yang; Yu Zhao; Nathan Faulkner; Jianbin Hu; Jennifer Baird; Wolfgang Baehr; Donnell J Creel; Kang Zhang
Autosomal dominant cone dystrophy caused by a novel mutation in the GCAP1 gene (GUCA1A).
Molecular vision 2005;11():143-51.
2005: Zhenglin Yang; Bernardo V Alvarez; Christina F Chakarova; Li Jiang; Goutam Karan; Jeanne M Frederick; Yu Zhao; Yves Sauvé; Xi Li; Eberhart Zrenner; Bernd Wissinger; Anneke I Den Hollander; Bradley Katz; Wolfgang Baehr; Frans P M Cremers; Joseph R Casey; Shomi S Bhattacharya; Kang Zhang
Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration.
Human molecular genetics 2005;14(2):255-65.
2004: Koji M Nishiguchi; Izabela Sokal; Lili Yang; Nirmalya Roychowdhury; Krzysztof Palczewski; Eliot L Berson; Thaddeus P Dryja; Wolfgang Baehr
A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration.
Investigative ophthalmology & visual science 2004;45(11):3863-70.
2004: Kimberly Howes; Yang Liu; Joshua L Dunaief; Ann H Milam; Jeanne M Frederick; Alexander Marks; Wolfgang Baehr
Receptor for advanced glycation end products and age-related macular degeneration.
Investigative ophthalmology & visual science 2004;45(10):3713-20.
2004: Krzysztof Palczewski; Izabela Sokal; Wolfgang Baehr
Guanylate cyclase-activating proteins: structure, function, and diversity.
Biochemical and biophysical research communications 2004;322(4):1123-30.
2004: Yoshikazu Imanishi; Lili Yang; Izabela Sokal; Slawomir Filipek; Krzysztof Palczewski; Wolfgang Baehr
Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (Fugu rubripes).
Journal of molecular evolution 2004;59(2):204-17.
2004: Matthew L Batten; Yoshikazu Imanishi; Tadao Maeda; Daniel C Tu; Alexander R Moise; Darin Bronson; Daniel E Possin; Russell N Van Gelder; Wolfgang Baehr; Krzysztof Palczewski
Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.
The Journal of biological chemistry 2004;279(11):10422-32.
2004: Yoshikazu Imanishi; Matthew L Batten; David W Piston; Wolfgang Baehr; Krzysztof Palczewski
Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye.
The Journal of cell biology 2004;164(3):373-83.
2004: Houbin Zhang; Xiao-hui Liu; Kai Zhang; Ching-Kang Chen; Jeanne M Frederick; Glenn D Prestwich; Wolfgang Baehr
Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein.
The Journal of biological chemistry 2004;279(1):407-13.
2003: Bryan Jones; Carl B Watt; Jeanne M Frederick; Wolfgang Baehr; Ching-Kang Chen; Edward M Levine; Ann H Milam; Matthew M LaVail; Robert E Marc
Retinal remodeling triggered by photoreceptor degenerations.
The Journal of comparative neurology 2003;464(1):1-16.
2003: Xian-Mei Zhang; Zhenglin Yang; Goutam Karan; Takao Hashimoto; Wolfgang Baehr; Xian-Jie Yang; Kang Zhang
Elovl4 mRNA distribution in the developing mouse retina and phylogenetic conservation of Elovl4 genes.
Molecular vision 2003;9():301-7.
2003: Houbin Zhang; Nicolás Cuenca; Tamara Ivanova; Jill Church-Kopish; Jeanne M Frederick; Peter R MacLeish; Wolfgang Baehr
Identification and light-dependent translocation of a cone-specific antigen, cone arrestin, recognized by monoclonal antibody 7G6.
Investigative ophthalmology & visual science 2003;44(7):2858-67.
2003: Houbin Zhang; Wei Huang; Haikun Zhang; Xuemei Zhu; Cheryl M Craft; Wolfgang Baehr; Ching-Kang Chen
Light-dependent redistribution of visual arrestins and transducin subunits in mice with defective phototransduction.
Molecular vision 2003;9():231-7.
2003: Mark Pennesi; Kimberly Howes; Wolfgang Baehr; Samuel M Wu
Guanylate cyclase-activating protein (GCAP) 1 rescues cone recovery kinetics in GCAP1/GCAP2 knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6783-8.
2003: Kimberly Howes; Jeanne M Frederick; Alexander Marks; Wolfgang Baehr
Progressive pathways in age-related macular degeneration.
Advances in experimental medicine and biology 2003;533():91-6.
2002: Kimberly Howes; Mark Pennesi; Izabela Sokal; Jill Church-Kopish; Ben Schmidt; David Margolis; Jeanne M Frederick; Fred Rieke; Krzysztof Palczewski; Samuel M Wu; Peter B Detwiler; Wolfgang Baehr
GCAP1 rescues rod photoreceptor response in GCAP1/GCAP2 knockout mice.
The EMBO journal 2002;21(7):1545-54.
2002: Izabela Sokal; Andrei Alekseev; Wolfgang Baehr; Francoise Haeseleer; Krzysztof Palczewski
Soluble fusion proteins between single transmembrane photoreceptor guanylyl cyclases and their activators.
Biochemistry 2002;41(1):251-7.
2002: Yoshikazu Imanishi; Ning Li; Izabela Sokal; Mathew E Sowa; Olivier Lichtarge; Theodore G Wensel; David A Saperstein; Wolfgang Baehr; Krzysztof Palczewski
Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man.
The European journal of neuroscience 2002;15(1):63-78.
2001: Ching-Kang Chen; Kang Zhang; Jill Church-Kopish; Wei Huang; Haikun Zhang; Yu-Jiun Chen; Jeanne M Frederick; Wolfgang Baehr
Characterization of human GRK7 as a potential cone opsin kinase.
Molecular vision 2001;7():305-13.
2001: Izabela Sokal; Ning Li; C S Klug; Slawomir Filipek; W L Hubbell; Wolfgang Baehr; Krzysztof Palczewski
Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies.
The Journal of biological chemistry 2001;276(46):43361-73.
2001: Ana Mendez; Marie E Burns; Izabela Sokal; Alexander M Dizhoor; Wolfgang Baehr; K Palczewski; Denis A Baylor; Jeannie Chen
Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9948-53.
2001: Ning Li; Izabela Sokal; J Darin Bronson; Krzysztof Palczewski; Wolfgang Baehr
Identification of functional regions of guanylate cyclase-activating protein 1 (GCAP1) using GCAP1/GCIP chimeras.
Biological chemistry 2001;382(8):1179-88.
2001: JK McBee; Krzysztof Palczewski; Wolfgang Baehr; David R Pepperberg
Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina.
Progress in retinal and eye research 2001;20(4):469-529.
2001: Jeanne M Frederick; Nataliia V Krasnoperova; K Hoffmann; Jill Church-Kopish; K Rüther; Kimberly Howes; Janis Lem; Wolfgang Baehr
Mutant rhodopsin transgene expression on a null background.
Investigative ophthalmology & visual science 2001;42(3):826-33.
2000: Izabela Sokal; Ning Li; Christophe Verlinde; Francoise Haeseleer; Wolfgang Baehr; Krzysztof Palczewski
Ca(2+)-binding proteins in the retina: from discovery to etiology of human disease(1).
Biochimica et biophysica acta 2000;1498(2-3):233-51.
2000: Krzysztof Palczewski; A S Polans; Wolfgang Baehr; James B Ames
Ca(2+)-binding proteins in the retina: structure, function, and the etiology of human visual diseases.
BioEssays : news and reviews in molecular, cellular and developmental biology 2000;22(4):337-50.
2000: Jeanne M Frederick; J Darin Bronson; Wolfgang Baehr
Animal models of inherited retinal diseases.
Methods in enzymology 2000;316():515-26.
1999: Craig D Thulin; Kimberly Howes; C D Driscoll; JR Savage; T A Rand; Wolfgang Baehr; Barry M Willardson
The immunolocalization and divergent roles of phosducin and phosducin-like protein in the retina.
Molecular vision 1999;5():40.
1999: Kang Zhang; Kimberly Howes; W He; J Darin Bronson; M J Pettenati; C Chen; Krzysztof Palczewski; Theodore G Wensel; Wolfgang Baehr
Structure, alternative splicing, and expression of the human RGS9 gene.
Gene 1999;240(1):23-34.
1999: Susan L Semple-Rowland; Patrick Larkin; J Darin Bronson; Keith R Nykamp; Wolfgang J Streit; Wolfgang Baehr
Characterization of the chicken GCAP gene array and analyses of GCAP1, GCAP2, and GC1 gene expression in normal and rd chicken pineal.
Molecular vision 1999;5():14.
1999: Izabela Sokal; AE Otto-Bruc; Irina Surgucheva; Christophe Verlinde; C K Wang; Wolfgang Baehr; Krzysztof Palczewski
Conformational changes in guanylyl cyclase-activating protein 1 (GCAP1) and its tryptophan mutants as a function of calcium concentration.
The Journal of biological chemistry 1999;274(28):19829-37.
1999: Patrick Larkin; Wolfgang Baehr; Susan L Semple-Rowland
Circadian regulation of iodopsin and clock is altered in the retinal degeneration chicken retina.
Brain research. Molecular brain research 1999;70(2):253-63.
1999: Francoise Haeseleer; Izabela Sokal; Ning Li; M Pettenati; N Rao; Darin Bronson; R Wechter; Wolfgang Baehr; Krzysztof Palczewski
Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily.
The Journal of biological chemistry 1999;274(10):6526-35.
1999: Andrei Surguchov; Irina Surgucheva; Eduardo Solessio; Wolfgang Baehr
Synoretin--A new protein belonging to the synuclein family.
Molecular and cellular neurosciences 1999;13(2):95-103.
1998: N Li; Wolfgang Baehr
Expression and characterization of human PDEdelta and its Caenorhabditis elegans ortholog CEdelta.
FEBS letters 1998;440(3):454-7.
1998: Izabela Sokal; Ning Li; Irina Surgucheva; Martin J Warren; Annette M Payne; S S Bhattacharya; Wolfgang Baehr; Krzysztof Palczewski
GCAP1 (Y99C) mutant is constitutively active in autosomal dominant cone dystrophy.
Molecular cell 1998;2(1):129-33.
1998: Kimberly Howes; J Darin Bronson; Y L Dang; Ning Li; Kang Zhang; C Ruiz; B Helekar; M Lee; I Subbaraya; Helga Kolb; J Chen; Wolfgang Baehr
Gene array and expression of mouse retina guanylate cyclase activating proteins 1 and 2.
Investigative ophthalmology & visual science 1998;39(6):867-75.
1998: Cheil Moon; P Jaberi; AE Otto-Bruc; Wolfgang Baehr; Krzysztof Palczewski; Gabriele V Ronnett
Calcium-sensitive particulate guanylyl cyclase as a modulator of cAMP in olfactory receptor neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(9):3195-205.
1998: N Li; SK Florio; M J Pettenati; P N Rao; Joseph A Beavo; Wolfgang Baehr
Characterization of human and mouse rod cGMP phosphodiesterase delta subunit (PDE6D) and chromosomal localization of the human gene.
Genomics 1998;49(1):76-82.
1998: Ning Li; Robert Fariss; Kang Zhang; AE Otto-Bruc; Francoise Haeseleer; Darin Bronson; N Qin; Akio Yamazaki; I Subbaraya; Ann H Milam; Krzysztof Palczewski; Wolfgang Baehr
Guanylate-cyclase-inhibitory protein is a frog retinal Ca2+-binding protein related to mammalian guanylate-cyclase-activating proteins.
European journal of biochemistry / FEBS 1998;252(3):591-9.
1998: Susan L Semple-Rowland; N R Lee; J P Van Hooser; Krzysztof Palczewski; Wolfgang Baehr
A null mutation in the photoreceptor guanylate cyclase gene causes the retinal degeneration chicken phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1271-6.
1998: M Rudnicka-Nawrot; Irina Surgucheva; JD Hulmes; Francoise Haeseleer; Izabela Sokal; John W Crabb; Wolfgang Baehr; Krzysztof Palczewski
Changes in biological activity and folding of guanylate cyclase-activating protein 1 as a function of calcium.
Biochemistry 1998;37(1):248-57.
1997: AE Otto-Bruc; Robert Fariss; Francoise Haeseleer; Jing Huang; J Buczyłko; Irina Surgucheva; Wolfgang Baehr; Ann H Milam; Krzysztof Palczewski
Localization of guanylate cyclase-activating protein 2 in mammalian retinas.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4727-32.
1997: AE Otto-Bruc; J Buczylko; Irina Surgucheva; I Subbaraya; M Rudnicka-Nawrot; John W Crabb; Anatol Arendt; Paul A Hargrave; Wolfgang Baehr; Krzysztof Palczewski
Functional reconstitution of photoreceptor guanylate cyclase with native and mutant forms of guanylate cyclase-activating protein 1.
Biochemistry 1997;36(14):4295-302.
1997: X Zhao; Francoise Haeseleer; Robert Fariss; Jing Huang; Wolfgang Baehr; Ann H Milam; Krzysztof Palczewski
Molecular cloning and localization of rhodopsin kinase in the mammalian pineal.
Visual neuroscience 1997;14(2):225-32.
1997: Andrei Surguchov; J Darin Bronson; P Banerjee; J A Knowles; C Ruiz; I Subbaraya; Krzysztof Palczewski; Wolfgang Baehr
The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1).
Genomics 1997;39(3):312-22.
1996: L Feng; I Subbaraya; N Yamamoto; Wolfgang Baehr; N Kraus-Friedmann
Expression of photoreceptor cyclic nucleotide-gated cation channel alpha subunit (CNGCalpha) in the liver and skeletal muscle.
FEBS letters 1996;395(1):77-81.
1996: Teresa Duda; RM Goraczniak; Irina Surgucheva; M Rudnicka-Nawrot; W A Gorczyca; Krzysztof Palczewski; Ari Sitaramayya; Wolfgang Baehr; Rameshwar K Sharma
Calcium modulation of bovine photoreceptor guanylate cyclase.
Biochemistry 1996;35(26):8478-82.
1996: Susan L Semple-Rowland; W A Gorczyca; J Buczylko; B S Helekar; C C Ruiz; I Subbaraya; Krzysztof Palczewski; Wolfgang Baehr
Expression of GCAP1 and GCAP2 in the retinal degeneration (rd) mutant chicken retina.
FEBS letters 1996;385(1-2):47-52.
1996: Dennis M Marcus; J G Lasudry; J L Carpenter; Jolene J Windle; Kimberly Howes; Muayyad R Al-Ubaidi; Wolfgang Baehr; Paul A Overbeek; Ramon L Font; Daniel M Albert
Trilateral tumors in four different lines of transgenic mice expressing SV40 T-antigen.
Investigative ophthalmology & visual science 1996;37(2):392-6.
1995: W A Gorczyca; A S Polans; Irina Surgucheva; I Subbaraya; Wolfgang Baehr; Krzysztof Palczewski
Guanylyl cyclase activating protein. A calcium-sensitive regulator of phototransduction.
The Journal of biological chemistry 1995;270(37):22029-36.
1995: R A Alvarez; Abboud J Ghalayini; P Xu; A Hardcastle; S Bhattacharya; P N Rao; M J Pettenati; R E Anderson; Wolfgang Baehr
cDNA sequence and gene locus of the human retinal phosphoinositide-specific phospholipase-C beta 4 (PLCB4).
Genomics 1995;29(1):53-61.
1994: I Subbaraya; C C Ruiz; B S Helekar; X Zhao; W A Gorczyca; M J Pettenati; P N Rao; Krzysztof Palczewski; Wolfgang Baehr
Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene.
The Journal of biological chemistry 1994;269(49):31080-9.
1994: N Qin; Wolfgang Baehr
Expression and mutagenesis of mouse rod photoreceptor cGMP phosphodiesterase.
The Journal of biological chemistry 1994;269(5):3265-71.
1993: Steven J Pittler; C E Keeler; Richard Sidman; Wolfgang Baehr
PCR analysis of DNA from 70-year-old sections of rodless retina demonstrates identity with the mouse rd defect.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9616-9.
1993: Muna I Naash; Joe G Hollyfield; Muayyad R Al-Ubaidi; Wolfgang Baehr
Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated murine opsin gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5499-503.
1993: M L Suber; Steven J Pittler; N Qin; G C Wright; V Holcombe; R H Lee; Cheryl M Craft; R N Lolley; Wolfgang Baehr; Richard L Hurwitz
Irish setter dogs affected with rod/cone dysplasia contain a nonsense mutation in the rod cGMP phosphodiesterase beta-subunit gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):3968-72.
1993: N Qin; Wolfgang Baehr
Expression of mouse rod photoreceptor cGMP phosphodiesterase gamma subunit in bacteria.
FEBS letters 1993;321(1):6-10.
1992: Muayyad R Al-Ubaidi; Ramon L Font; Alexander B Quiambao; M J Keener; Gregory I Liou; Paul A Overbeek; Wolfgang Baehr
Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter.
The Journal of cell biology 1992;119(6):1681-7.
1992: Steven J Pittler; Steven J Fliesler; Wolfgang Baehr
Primary structure of frog rhodopsin.
FEBS letters 1992;313(2):103-8.
1992: Dan S Gallagher; James E Womack; Wolfgang Baehr; Steven J Pittler
Syntenic assignments of visual transduction genes in cattle.
Genomics 1992;14(3):699-706.
1992: James F McGinnis; P L Stepanik; Wolfgang Baehr; I Subbaraya; V Lerious
Cloning and sequencing of the 23 kDa mouse photoreceptor cell-specific protein.
FEBS letters 1992;302(2):172-6.
1992: N Qin; Steven J Pittler; Wolfgang Baehr
In vitro isoprenylation and membrane association of mouse rod photoreceptor cGMP phosphodiesterase alpha and beta subunits expressed in bacteria.
The Journal of biological chemistry 1992;267(12):8458-63.
1992: M R Altherr; JJ Wasmuth; Michael F Seldin; J H Nadeau; Wolfgang Baehr; Steven J Pittler
Chromosome mapping of the rod photoreceptor cGMP phosphodiesterase beta-subunit gene in mouse and human: tight linkage to the Huntington disease region (4p16.3).
Genomics 1992;12(4):750-4.
1992: Steven J Pittler; A K Lee; M R Altherr; T A Howard; Michael F Seldin; Richard L Hurwitz; J J Wasmuth; Wolfgang Baehr
Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel.
The Journal of biological chemistry 1992;267(9):6257-62.
1992: Muayyad R Al-Ubaidi; Joe G Hollyfield; Paul A Overbeek; Wolfgang Baehr
Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1194-8.
1991: Steven J Pittler; Wolfgang Baehr
Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8322-6.
1991: Wolfgang Baehr; M S Champagne; A K Lee; Steven J Pittler
Complete cDNA sequences of mouse rod photoreceptor cGMP phosphodiesterase alpha- and beta-subunits, and identification of beta'-, a putative beta-subunit isozyme produced by alternative splicing of the beta-subunit gene.
FEBS letters 1991;278(1):107-14.
1991: Gregory I Liou; L Geng; Wolfgang Baehr
Interphotoreceptor retinoid-binding protein: biochemistry and molecular biology.
Progress in clinical and biological research 1991;362():115-37.
1991: Steven J Pittler; Wolfgang Baehr
The molecular genetics of retinal photoreceptor proteins involved in cGMP metabolism.
Progress in clinical and biological research 1991;362():33-66.
1991: L M Holbach; Ramon L Font; Wolfgang Baehr; Steven J Pittler
HSV antigens and HSV DNA in avascular and vascularized lesions of human herpes simplex keratitis.
Current eye research 1991;10 Suppl():63-8.
1990: Muayyad R Al-Ubaidi; Steven J Pittler; M S Champagne; J T Triantafyllos; James F McGinnis; Wolfgang Baehr
Mouse opsin. Gene structure and molecular basis of multiple transcripts.
The Journal of biological chemistry 1990;265(33):20563-9.
1990: Gregory I Liou; L Geng; Muayyad R Al-Ubaidi; Suraporn Matragoon; G Hanten; Wolfgang Baehr; Paul A Overbeek
Tissue-specific expression in transgenic mice directed by the 5'-flanking sequences of the human gene encoding interphotoreceptor retinoid-binding protein.
The Journal of biological chemistry 1990;265(15):8373-6.
1990: Steven J Pittler; Wolfgang Baehr; J J Wasmuth; D G McConnell; M S Champagne; P vanTuinen; David Ledbetter; R L Davis
Molecular characterization of human and bovine rod photoreceptor cGMP phosphodiesterase alpha-subunit and chromosomal localization of the human gene.
Genomics 1990;6(2):272-83.
1989: Gregory I Liou; Din-Pow Ma; Y W Yang; L Geng; C Zhu; Wolfgang Baehr
Human interstitial retinoid-binding protein. Gene structure and primary structure.
The Journal of biological chemistry 1989;264(14):8200-6.
1988: Wolfgang Baehr; J D Falk; K Bugra; J T Triantafyllos; James F McGinnis
Isolation and analysis of the mouse opsin gene.
FEBS letters 1988;238(2):253-6.