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G J L Kaspers

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V Caretti; J Cloos; I Horsman; E Hulleman; M H A Jansen; M Bugiani; T Lagerweij; David P Noske; P van der Valk; D G van Vuurden; W Peter Vandertop; P Wesseling; H Wessels; T Wurdinger; G J L Kaspers
Implementation of a multi-institutional diffuse intrinsic pontine glioma autopsy protocol and characterization of a primary cell culture.
A Overbeek; W J E Tissing; M H van den Berg; Marry M van den Heuvel-Eibrink; E van Dulmen-den Broeder; Flora E van Leeuwen; A B Versluys; Dorine Bresters; C W P M Hukkelhoven; G J L Kaspers; L C Kremer; Cornelis B Lambalk; J J Loonen
Validity of self-reported data on pregnancies for childhood cancer survivors: a comparison with data from a nationwide population-based registry.
Maartje S Gordijn; Peter M Hoogerbrugge; Jaap Huisman; Marc B Bierings; Reinoud J Gemke; Raphaële R van Litsenburg; G J L Kaspers
Sleep, fatigue, depression, and quality of life in survivors of childhood acute lymphoblastic leukemia.

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2013: V Caretti; J Cloos; I Horsman; E Hulleman; M H A Jansen; M Bugiani; T Lagerweij; David P Noske; P van der Valk; D G van Vuurden; W Peter Vandertop; P Wesseling; H Wessels; T Wurdinger; G J L Kaspers
Implementation of a multi-institutional diffuse intrinsic pontine glioma autopsy protocol and characterization of a primary cell culture.
Neuropathology and applied neurobiology 2013;39(4):426-36.
2013: A Overbeek; W J E Tissing; M H van den Berg; Marry M van den Heuvel-Eibrink; E van Dulmen-den Broeder; Flora E van Leeuwen; A B Versluys; Dorine Bresters; C W P M Hukkelhoven; G J L Kaspers; L C Kremer; Cornelis B Lambalk; J J Loonen
Validity of self-reported data on pregnancies for childhood cancer survivors: a comparison with data from a nationwide population-based registry.
Human reproduction (Oxford, England) 2013;28(3):819-27.
2013: Maartje S Gordijn; Peter M Hoogerbrugge; Jaap Huisman; Marc B Bierings; Reinoud J Gemke; Raphaële R van Litsenburg; G J L Kaspers
Sleep, fatigue, depression, and quality of life in survivors of childhood acute lymphoblastic leukemia.
Pediatric blood & cancer 2013;60(3):479-85.
2013: Mahban Irandoust; G J L Kaspers; Pamela Kearns; Dirk Reinhardt; Karin Schornagel; Edwin Sonneveld; Peter J Valk; Ellen M van Beek; Arjan A van de Loosdrecht; Mercan Akyuz; Julian Alvarez Zarate; A J F Broekhuizen; Jacqueline Cloos; Eva A Coenen; Ursula Creutzig; Eveline S J M de Bont; Ruud Delwel; Isabelle Hubeek; Marry M van den Heuvel-Eibrink; Christian M Zwaan; Timo K van den Berg
Engagement of SIRPα inhibits growth and induces programmed cell death in acute myeloid leukemia cells.
PloS one 2013;8(1):e52143.
2012: Ilse M G Hageman; Carin M Damen-Korbijn; V de Haas; Annemarie M L Peek; G J L Kaspers
Value of routine bone marrow examination in pediatric acute myeloid leukemia (AML): a study of the Dutch Childhood Oncology Group (DCOG).
Pediatric blood & cancer 2012;59(7):1239-44.
2012: Eva A Coenen; Eveline S J M de Bont; Valerie de Haas; Emma M C Driessen; G J L Kaspers; Rolf Marschalek; Claus Meyer; Rob Pieters; Dirk Reinhardt; Ronald W Stam; Jan Stary; Susan T C J M Arentsen-Peters; Andre Baruchel; Christian M Zwaan; Marry M van den Heuvel-Eibrink
CBL mutations do not frequently occur in paediatric acute myeloid leukaemia.
British journal of haematology 2012;159(5):577-84.
2012: Ursula Creutzig; Eveline S J M de Bont; Michael Dworzak; Brenda Gibson; Jochen Harbott; Henrik Hasle; Donna Johnston; G J L Kaspers; Akitoshi Kinoshita; Thomas Lehrnbecher; Guy Leverger; Ester Mejstrikova; Soheil Meshinchi; Andrea Pession; Susana C Raimondi; Dirk Reinhardt; Jan Stary; Lillian Sung; Marry M van den Heuvel-Eibrink; Christian M Zwaan; Souichi Adachi
Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel.
Blood 2012;120(16):3187-205.
2012: Marc H A Jansen; G J L Kaspers
A new era for children with diffuse intrinsic pontine glioma: hope for cure?
Expert review of anticancer therapy 2012;12(9):1109-12.
2012: R R G Knops; W J W Kollen; J L Loeffen; H N Caron; R P M G Hermens; M Hilbink-Smolders; Marlies E J L Hulscher; G J L Kaspers; L C M Kremer
High-quality care for all children with cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(7):1906-11.
2012: C Bachas; Y G Assaraf; G J L Kaspers; Angèle Kelder; Z J Kwidama; Gerrit J Schuurhuis; A N Snel; F Wouters; Jacqueline Cloos
The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse.
Leukemia 2012;26(6):1313-20.
2012: N E Franke; D P Geerke; G Jansen; G J L Kaspers; C J Kirk; D Niewerth; A D Schimmer; J van Meerloo; Christina H van Zantwijk; K Vojtekova; Sonja Zweegman; Y G Assaraf; E T Chan; Jacqueline Cloos
Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells.
Leukemia 2012;26(4):757-68.
2012: M H A Jansen; D G van Vuurden; W P Vandertop; G J L Kaspers
Diffuse intrinsic pontine gliomas: a systematic update on clinical trials and biology.
Cancer treatment reviews 2012;38(1):27-35.
2011: Brian Balgobind; Andre Baruchel; Berna Beverloo; Jean-Michel Cayuela; Jacqueline Cloos; Ursula Creutzig; Valerie de Haas; Jochen Harbott; Iris H I M Hollink; G J L Kaspers; Rob Pieters; Dirk Reinhardt; Jan Stary; Anne R M von Bergh; Zuzana Zemanova; Martin Zimmermann; Christian M Zwaan; Susan T C J M Arentsen-Peters; Marry M van den Heuvel-Eibrink
Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia.
Haematologica 2011;96(10):1478-87.
2011: J PosthumaDeBoer; M Adhiambo Witlox; G J L Kaspers; B J van Royen
Molecular alterations as target for therapy in metastatic osteosarcoma: a review of literature.
Clinical & experimental metastasis 2011;28(5):493-503.
2011: Gabriele Escherich; Ulrich Göbel; Ulrike B Graubner; Martin Horstmann; Gritta Janka; Norbert Jorch; G J L Kaspers; Karin Kazemier; Arnulf Pekrun; Rob Pieters; Anja Tröger; Martin Zimmermann; Udo zur Stadt; Monique L den Boer
The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).
Haematologica 2011;96(6):854-62.
2011: I L M Klaassen; V de Haas; J A E van Wijk; G J L Kaspers; Maarten F Bijlsma; A Bökenkamp
Pyuria is absent during urinary tract infections in neutropenic patients.
Pediatric blood & cancer 2011;56(5):868-70.
2011: Jenny E Kuipers; Eva A Coenen; Brian Balgobind; Jan Stary; Andre Baruchel; Valerie de Haas; Eveline S J M de Bont; Dirk Reinhardt; G J L Kaspers; Jacqueline Cloos; Astrid A Danen-van Oorschot; Monique L den Boer; Rolf Marschalek; Claus Meyer; Rob Pieters; Christian M Zwaan; Marry M van den Heuvel-Eibrink
High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).
Blood 2011;117(3):928-35.
2010: Brian Balgobind; Christian M Zwaan; Dirk Reinhardt; T J C M Arentsen-Peters; I H I M Hollink; V de Haas; G J L Kaspers; Eveline S J M de Bont; A Baruchel; Jan Stary; Claus Meyer; Rolf Marschalek; Ursula Creutzig; Monique L den Boer; Rob Pieters; Marry M van den Heuvel-Eibrink
High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome.
Leukemia 2010;24(12):2048-55.
2010: F W Neervoort; W J R van Ouwerkerk; H Folkersma; G J L Kaspers; W Peter Vandertop
Surgical morbidity and mortality of pediatric brain tumors: a single center audit.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2010;26(11):1583-92.
2010: Bianca F Goemans; Christian M Zwaan; Jacqueline Cloos; Desiree de Lange; Anne H Loonen; Dirk Reinhardt; Karel Hählen; Brenda E S Gibson; Ursula Creutzig; G J L Kaspers
FLT3 and KIT mutated pediatric acute myeloid leukemia (AML) samples are sensitive in vitro to the tyrosine kinase inhibitor SU11657.
Leukemia research 2010;34(10):1302-7.
2010: Denise Niewerth; Ursula Creutzig; Marc Bierings; G J L Kaspers
A review on allogeneic stem cell transplantation for newly diagnosed pediatric acute myeloid leukemia.
Blood 2010;116(13):2205-14.
2010: Hendrik J M de Jonge; Peter J M Valk; Nic J G M Veeger; Arja ter Elst; Monique L den Boer; Jacqueline Cloos; Valérie de Haas; Marry M van den Heuvel-Eibrink; G J L Kaspers; Christian M Zwaan; Willem A Kamps; Bob Löwenberg; Eveline S J M de Bont
High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia.
Blood 2010;116(10):1747-54.
2010: Annette Sander; Martin Zimmermann; Michael Dworzak; Gudrun Fleischhack; C von Neuhoff; Dirk Reinhardt; G J L Kaspers; Ursula Creutzig
Consequent and intensified relapse therapy improved survival in pediatric AML: results of relapse treatment in 379 patients of three consecutive AML-BFM trials.
Leukemia 2010;24(8):1422-8.
2010: Martine C de Vries; Jan M Wit; Dirk P Engberts; G J L Kaspers; Evert van Leeuwen
Pediatric oncologists' attitudes towards involving adolescents in decision-making concerning research participation.
Pediatric blood & cancer 2010;55(1):123-8.
2010: Godefridus J Peters; J Hodzic; B Ortega; Elisa Giovannetti; Auke D Adema; Richard Broekhuizen; G J L Kaspers; Isabelle Hubeek
Methylation specific PCR to characterize methylation of the promoter of deoxycytidine kinase.
Nucleosides, nucleotides & nucleic acids 2010;29(4-6):408-13.
2010: M H van den Berg; E van Dulmen-den Broeder; A Overbeek; J W R Twisk; R Schats; F E van Leeuwen; G J L Kaspers; C B Lambalk
Comparison of ovarian function markers in users of hormonal contraceptives during the hormone-free interval and subsequent natural early follicular phases.
Human reproduction (Oxford, England) 2010;25(6):1520-7.
2010: Brian Balgobind; S Lugthart; I H Hollink; S T J C M Arentsen-Peters; Elisabeth R van Wering; Siebold S N de Graaf; Dirk Reinhardt; Ursula Creutzig; G J L Kaspers; E S J M de Bont; Jan Stary; Jan Trka; M Zimmermann; Berna Beverloo; Rob Pieters; Ruud Delwel; Christian M Zwaan; Marry M van den Heuvel-Eibrink
EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia.
Leukemia 2010;24(5):942-9.
2010: Christian M Zwaan; Dirk Reinhardt; Martin Zimmerman; Henrik Hasle; Jan Stary; Batia Stark; Michael Dworzak; Ursula Creutzig; G J L Kaspers
Salvage treatment for children with refractory first or second relapse of acute myeloid leukaemia with gemtuzumab ozogamicin: results of a phase II study.
British journal of haematology 2010;148(5):768-76.
2009: Iris H I M Hollink; Marry M van den Heuvel-Eibrink; Martin Zimmermann; Brian Balgobind; Susan T C J M Arentsen-Peters; Marielle Alders; Andre Willasch; G J L Kaspers; Jan Trka; Andre Baruchel; Siebold S N de Graaf; Ursula Creutzig; Rob Pieters; Dirk Reinhardt; Christian M Zwaan
Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia.
Blood 2009;113(23):5951-60.
2009: Robert de Jonge; Wim J E Tissing; Jan Hendrik Hooijberg; Gerrit Jansen; G J L Kaspers; Jan Lindemans; Godefridus J Peters; Rob Pieters
Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia.
Blood 2009;113(10):2284-9.
2009: C A M Drukker; Hugo A Heij; L C D Wijnaendts; J I M L Verbeke; G J L Kaspers
Paraneoplastic gastro-intestinal anti-Hu syndrome in neuroblastoma.
Pediatric blood & cancer 2009;52(3):396-8.
2009: I H I M Hollink; Christian M Zwaan; M Zimmermann; T C J M Arentsen-Peters; Rob Pieters; J Cloos; G J L Kaspers; Siebold S N de Graaf; J Harbott; U Creutzig; Dirk Reinhardt; Marry M van den Heuvel-Eibrink; C Thiede
Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML.
Leukemia 2009;23(2):262-70.
2008: Eric G Haarman; G J L Kaspers; Rob Pieters; M M A Rottier; Anjo J P Veerman
Circumvention of glucocorticoid resistance in childhood leukemia.
Leukemia research 2008;32(9):1417-23.
2008: Isabelle Hubeek; Elisa Giovannetti; A J F Broekhuizen; M Pastor-Anglada; G J L Kaspers; Godefridus J Peters
Immunocytochemical detection of hENT1 and hCNT1 in normal tissues, lung cancer cell lines, and NSCLC patient samples.
Nucleosides, nucleotides & nucleic acids 2008;27(6):787-93.
2008: Isabelle Hubeek; Elizabeth M Comijn; Clasina L Van der Wilt; Ronald L Merriman; Jose Padron; G J L Kaspers; Godefridus J Peters
CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo.
Oncology reports 2008;19(6):1517-23.
2008: Elisabeth Van Dijk; E van Dulmen-den Broeder; G J L Kaspers; E W C M van Dam; K I Braam; Jaap Huisman
Psychosexual functioning of childhood cancer survivors.
Psycho-oncology 2008;17(5):506-11.
2008: Brian Balgobind; Pieter Van Vlierberghe; Ans M W van den Ouweland; Berna Beverloo; Joan N R Terlouw-Kromosoeto; Elisabeth R van Wering; Dirk Reinhardt; Martin Horstmann; G J L Kaspers; Rob Pieters; Christian M Zwaan; Marry M van den Heuvel-Eibrink; Jules P P Meijerink
Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis.
Blood 2008;111(8):4322-8.
2008: Hendrik J M de Jonge; Alida C Weidenaar; Arja ter Elst; H Marike Boezen; Frank J G Scherpen; Jessica C A Bouma-Ter Steege; G J L Kaspers; Bianca Goemans; Ursula Creutzig; Martin Zimmermann; Willem A Kamps; Eveline S J M de Bont
Endogenous vascular endothelial growth factor-C expression is associated with decreased drug responsiveness in childhood acute myeloid leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(3):924-30.
2008: Corine J Hess; Najim Ameziane; Gerrit J Schuurhuis; a Errami; Fedor Denkers; G J L Kaspers; Jacqueline Cloos; Hans Joenje; Dirk Reinhardt; Gert Ossenkoppele; Christian M Zwaan; Quinten Waisfisz
Hypermethylation of the FANCC and FANCL promoter regions in sporadic acute leukaemia.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2008;30(4):299-306.
2008: Harm C A Graat; Victor W van Beusechem; Frederik H E Schagen; M Adhiambo Witlox; Eugenie S Kleinerman; Marco N Helder; Winald Gerritsen; G J L Kaspers; Paul I J M Wuisman
Intravenous administration of the conditionally replicative adenovirus Ad5-Delta24RGD induces regression of osteosarcoma lung metastases.
Molecular cancer 2008;7():9.
2007: G J L Kaspers; Christian M Zwaan
Pediatric acute myeloid leukemia: towards high-quality cure of all patients.
Haematologica 2007;92(11):1519-32.
2007: Ruud Oerlemans; Jacqueline M Vink; B A C Dijkmans; Yehuda G Assaraf; Marjolein van Miltenburg; Joost van der Heijden; Ilan Ifergan; Willem F Lems; Rik J Scheper; G J L Kaspers; Jacqueline Cloos; Gerrit Jansen
Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor alpha and glucocorticoid induced apoptosis.
Annals of the rheumatic diseases 2007;66(10):1289-95.
2007: Harm C A Graat; Jan E Carette; Frederik H E Schagen; Lyubomir T Vassilev; Winald Gerritsen; G J L Kaspers; Paul I J M Wuisman; Victor W van Beusechem
Enhanced tumor cell kill by combined treatment with a small-molecule antagonist of mouse double minute 2 and adenoviruses encoding p53.
Molecular cancer therapeutics 2007;6(5):1552-61.
2007: Jan E Carette; Harm C A Graat; Frederik H E Schagen; D C Jeroen Mastenbroek; Marianne G Rots; Hidde J Haisma; Geny M M Groothuis; Gerard R Schaap; Johannes Bras; G J L Kaspers; Paul I J M Wuisman; Winald Gerritsen; Victor W van Beusechem
A conditionally replicating adenovirus with strict selectivity in killing cells expressing epidermal growth factor receptor.
Virology 2007;361(1):56-67.
2006: Soheil Meshinchi; Todd A Alonzo; Derek L Stirewalt; Michel Zwaan; Martin Zimmerman; Dirk Reinhardt; G J L Kaspers; Nyla A Heerema; Robert B Gerbing; Beverly J Lange; Jerald P Radich
Clinical implications of FLT3 mutations in pediatric AML.
Blood 2006;108(12):3654-61.
2006: Bianca Goemans; Christian M Zwaan; Dirk Reinhardt; Brenda E S Gibson; Karel Hählen; G J L Kaspers
A comparison of the in vitro cytotoxicity of daunorubicin and liposomal daunorubicin in pediatric acute leukemia.
Haematologica 2006;91(11):1573-4.
2006: G J L Kaspers; Dirk Reinhardt; Gudrun Fleischhack; H Armendariz; Batia Stark; Christian M Zwaan; Martin Zimmermann; Ursula Creutzig
Low efficacy of methotrexate in childhood acute myeloid leukemia (AML): single-agent therapeutic window study in relapsed AML.
Pediatric blood & cancer 2006;47(5):539-42.
2006: Jacqueline M Vink; Jacqueline Cloos; G J L Kaspers
Proteasome inhibition as novel treatment strategy in leukaemia.
British journal of haematology 2006;134(3):253-62.
2006: Jacqueline Cloos; Bianca Goemans; Corine J Hess; Johan W van Oostveen; Quinten Waisfisz; S Corthals; Desiree de Lange; N Boeckx; Karel Hählen; Dirk Reinhardt; Ursula Creutzig; Gerrit J Schuurhuis; Ch M Zwaan; G J L Kaspers
Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples.
Leukemia 2006;20(7):1217-20.
2006: Jan Hendrik Hooijberg; N A de Vries; G J L Kaspers; Rob Pieters; Gerrit Jansen; Godefridus J Peters
Multidrug resistance proteins and folate supplementation: therapeutic implications for antifolates and other classes of drugs in cancer treatment.
Cancer chemotherapy and pharmacology 2006;58(1):1-12.
2006: Harm C A Graat; M Adhiambo Witlox; Frederik H E Schagen; G J L Kaspers; Marco N Helder; Johannes Bras; Gerard R Schaap; Winald Gerritsen; Paul I J M Wuisman; Victor W van Beusechem
Different susceptibility of osteosarcoma cell lines and primary cells to treatment with oncolytic adenovirus and doxorubicin or cisplatin.
British journal of cancer 2006;94(12):1837-44.
2006: Christian M Zwaan; Monique L den Boer; Karin M Kazemier; Karel Hählen; Anne H Loonen; Dirk Reinhardt; Ursula Creutzig; G J L Kaspers; Rob Pieters
Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia?
Blood 2006;107(12):4975-6; author reply 4976-7.
2006: Mark Luttjeboer; G J L Kaspers
Medulloblastoma: need for targeted treatment.
Expert review of anticancer therapy 2006;6(5):649-52.
2006: R S Blokker; L M E Smit; Cor van den Bos; P C Overberg; H N Caron; G J L Kaspers
[A boy with acute cerebellar ataxia without opsoclonus caused by neuroblastoma].
Nederlands tijdschrift voor geneeskunde 2006;150(14):799-803.
2006: Ruud Oerlemans; Joost van der Heijden; Jacqueline M Vink; B A C Dijkmans; G J L Kaspers; Willem F Lems; George L Scheffer; Ilan Ifergan; Rik J Scheper; Jacqueline Cloos; Yehuda G Assaraf; Gerrit Jansen
Acquired resistance to chloroquine in human CEM T cells is mediated by multidrug resistance-associated protein 1 and provokes high levels of cross-resistance to glucocorticoids.
Arthritis and rheumatism 2006;54(2):557-68.
2006: Auke D Adema; L Zuurbier; Karijn Floor; Isabelle Hubeek; G J L Kaspers; F Albertoni; Godefridus J Peters
Cellular resistance against troxacitabine in human cell lines and pediatric patient acute myeloid leukemia blast cells.
Nucleosides, nucleotides & nucleic acids 2006;25(9-11):981-6.
2006: Isabelle Hubeek; Godefridus J Peters; Richard Broekhuizen; Christian M Zwaan; Patricia Kaaijk; Elisabeth S van Wering; Brenda E S Gibson; Ursula Creutzig; Gritta E Janka-Schaub; Monique L den Boer; Rob Pieters; G J L Kaspers
In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia.
Haematologica 2006;91(1):17-23.
2006: Ronald W Stam; Isabelle Hubeek; Monique L den Boer; J G C A M Buijs-Gladdines; Ursula Creutzig; G J L Kaspers; Rob Pieters
MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia.
Leukemia 2006;20(1):179-82.
2005: Isabelle Hubeek; Ronald W Stam; Godefridus J Peters; Richard Broekhuizen; Jules P P Meijerink; Elisabeth R van Wering; Brenda E S Gibson; Ursula Creutzig; Christian M Zwaan; Jacqueline Cloos; Dirk J Kuik; Rob Pieters; G J L Kaspers
The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia.
British journal of cancer 2005;93(12):1388-94.
2005: G J L Kaspers; U Creutzig
Pediatric acute myeloid leukemia: international progress and future directions.
Leukemia 2005;19(12):2025-9.
2005: Gabriela Kardos; Christian M Zwaan; G J L Kaspers; Siebold S N de Graaf; Eveline S J M de Bont; A Postma; Jos P M Bökkerink; RS Weening; Anna van der Does-van den Berg; Elisabeth R van Wering; C Korbijn; Karel Hählen
Treatment strategy and results in children treated on three Dutch Childhood Oncology Group acute myeloid leukemia trials.
Leukemia 2005;19(12):2063-71.
2005: Bianca Goemans; Christian M Zwaan; Amy Harlow; Anne H Loonen; Brenda E S Gibson; Karel Hählen; Dirk Reinhardt; Ursula Creutzig; Michael C Heinrich; G J L Kaspers
In vitro profiling of the sensitivity of pediatric leukemia cells to tipifarnib: identification of T-cell ALL and FAB M5 AML as the most sensitive subsets.
Blood 2005;106(10):3532-7.
2005: Edske ter Bals; G J L Kaspers
Treatment of childhood acute myeloid leukemia.
Expert review of anticancer therapy 2005;5(5):917-29.
2005: Isabelle Hubeek; Godefridus J Peters; A J F Broekhuizen; J Sargent; Brenda E S Gibson; Ursula Creutzig; G J L Kaspers
Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia.
British journal of haematology 2005;131(2):219-22.
2005: Bianca Goemans; Christian M Zwaan; Simone Martinelli; Patina Harrell; Desiree de Lange; Claudio Carta; Dirk Reinhardt; Karel Hählen; Ursula Creutzig; Marco Tartaglia; Michael C Heinrich; G J L Kaspers
Differences in the prevalence of PTPN11 mutations in FAB M5 paediatric acute myeloid leukaemia.
British journal of haematology 2005;130(5):801-3.
2005: Bianca Goemans; Christian M Zwaan; M Miller; Martin Zimmermann; Amy Harlow; Soheil Meshinchi; Anne H Loonen; Karel Hählen; Dirk Reinhardt; Ursula Creutzig; G J L Kaspers; Michael C Heinrich
Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia.
Leukemia 2005;19(9):1536-42.
2005: R M Lingg; Georg Hempel; Marianne G Rots; Christina H van Zantwijk; Joachim Boos; G J L Kaspers
Effects and interaction of 7-hydroxy methotrexate and methotrexate in leukaemic cells ex vivo measured by the thymidylate synthase inhibition assay.
Cancer chemotherapy and pharmacology 2005;56(3):322-7.
2005: Robert de Jonge; Jan Hendrik Hooijberg; Bertrand D van Zelst; Gerrit Jansen; Gerritz Jansen; Christina H van Zantwijk; Christine H van Zantwijk; G J L Kaspers; Gert Jan L Kaspers; Godefridus J Peters; Frits G J Peters; Yaddanapudi Ravindranath; Rob Pieters; Jan Lindemans
Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia.
Blood 2005;106(2):717-20.
2005: Isabelle Hubeek; Godefridus J Peters; A J F Broekhuizen; Iannis Talianidis; Jennifer Sigmond; Brenda E S Gibson; Ursula Creutzig; G Giaccone; G J L Kaspers
Immunocytochemical detection of deoxycytidine kinase in haematological malignancies and solid tumours.
Journal of clinical pathology 2005;58(7):695-9.
2005: G J L Kaspers
6th International Symposium and expert workshops on Leukemia and Lymphoma. 17-19 March, 2005, Amsterdam, The Netherlands.
Expert review of anticancer therapy 2005;5(3):415-7.
2005: G J L Kaspers; Jelle J M Wijnands; Reinhard Hartmann; Loekie Huismans; Anne H Loonen; Arend Stackelberg; Günter Henze; Rob Pieters; Karel Hählen; Elisabeth R van Wering; Anjo J P Veerman
Immunophenotypic cell lineage and in vitro cellular drug resistance in childhood relapsed acute lymphoblastic leukaemia.
European journal of cancer (Oxford, England : 1990) 2005;41(9):1300-3.
2005: peter wielinga; Jan Hendrik Hooijberg; Sjofn Gunnarsdottir; Ietje Kathmann; Glen Reid; Noam Zelcer; Kasper van der Born; Marcel de Haas; Ingrid van der Heijden; G J L Kaspers; Jan Wijnholds; Gerrit Jansen; Godefridus Peters; Piet Borst
The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.
Cancer research 2005;65(10):4425-30.
2005: Harm C A Graat; Paul I J M Wuisman; Victor W van Beusechem; Jan E Carette; Winald Gerritsen; Johannes Bras; Gerard R Schaap; G J L Kaspers; Akira Ogose; Wenguang Gu; Hiroyuki Kawashima; Tetsuo Hotta
Coxsackievirus and adenovirus receptor expression on primary osteosarcoma specimens and implications for gene therapy with recombinant adenoviruses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(6):2445-7; author reply 2447-8.
2005: G J L Kaspers
Use of the differential staining cytotoxicity assay to predict chemosensitivity.
Methods in molecular medicine 2005;110():49-57.
2005: Bernard M Fine; G J L Kaspers; Minh Ho; Anne H Loonen; Linda M Boxer
A genome-wide view of the in vitro response to l-asparaginase in acute lymphoblastic leukemia.
Cancer research 2005;65(1):291-9.
2004: Isabelle Hubeek; Elena Litvinova; Godefridus J Peters; Richard Broekhuizen; Eric G Haarman; Dieuwke R Huismans; Jacqueline Cloos; Christian M Zwaan; Gudrun Fleischhack; Ursula Creutzig; G J L Kaspers
The effect of G-CSF on the in vitro cytotoxicity of cytarabine and fludarabine in the FLAG combination in pediatric acute myeloid leukemia.
International journal of oncology 2004;25(6):1823-9.
2004: Christian M Zwaan; G J L Kaspers
Possibilities for tailored and targeted therapy in paediatric acute myeloid leukaemia.
British journal of haematology 2004;127(3):264-79.
2004: Isabelle Hubeek; Godefridus J Peters; A J F Broekhuizen; G J L Kaspers
Modulation of cytarabine induced cytotoxicity using novel deoxynucleoside analogs in the HL60 cell line.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1513-6.
2004: Jan Hendrik Hooijberg; Godefridus J Peters; G J L Kaspers; peter wielinga; Anjo J P Veerman; Rob Pieters; Gerrit Jansen
Online fluorescent method to assess BCRP/ABCG2 activity in suspension cells.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1451-4.
2004: Isabelle Hubeek; Godefridus J Peters; A J F Broekhuizen; Iannis Talianidis; Antoinette Y N Schouten-Van Meeteren; Elisabeth R van Wering; B Gibson; Ursula Creutzig; G J L Kaspers
Immunocytochemical detection of deoxycytidine kinase in pediatric malignancies in relation to in vitro cytarabine sensitivity.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1351-6.
2004: U Creutzig; G J L Kaspers
Revised recommendations of the International Working Group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(16):3432-3.
2004: Dirk Reinhardt; Sylke Diekamp; Gudrun Fleischhack; C Corbacioglu; H Jürgens; Michael Dworzak; G J L Kaspers; Ursula Creutzig; Christian M Zwaan
Gemtuzumab ozogamicin (Mylotarg) in children with refractory or relapsed acute myeloid leukemia.
Onkologie 2004;27(3):269-72.
2004: Jan Hendrik Hooijberg; Gerrit Jansen; Yehuda G Assaraf; Ietje Kathmann; Rob Pieters; Adrie C Laan; Anjo J P Veerman; G J L Kaspers; Godefridus J Peters
Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1).
Biochemical pharmacology 2004;67(8):1541-8.
2004: Eric G Haarman; G J L Kaspers; Rob Pieters; M M A Rottier; Anjo J P Veerman
Glucocorticoid receptor alpha, beta and gamma expression vs in vitro glucocorticod resistance in childhood leukemia.
Leukemia 2004;18(3):530-7.
2004: Yotam Kaufman; Stavit Drori; Peter Cole; Barton A. Kamen; Jenny Sirota; Ilan Ifergan; Myriam Weyl Ben Arush; Ronit Elhasid; Dvora Sahar; G J L Kaspers; Gerrit Jansen; Larry H Matherly; Gideon Rechavi; Amos Toren; Yehuda G Assaraf
Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia.
Cancer 2004;100(4):773-82.
2003: Christian M Zwaan; Soheil Meshinchi; Jerald P Radich; Anjo J P Veerman; Dieuwke R Huismans; Leonhard Munske; Martina Podleschny; Karel Hählen; Rob Pieters; Martin Zimmermann; Dirk Reinhardt; Jochen Harbott; Ursula Creutzig; G J L Kaspers; Frank Griesinger
FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance.
Blood 2003;102(7):2387-94.
2003: Monique L den Boer; Dieter Harms; Rob Pieters; Karin M Kazemier; U Gobel; Dieter Körholz; Ulrike B Graubner; R J Haas; Norbert Jorch; Hans J Spaar; G J L Kaspers; Willem A Kamps; Anna van der Does-van den Berg; Elisabeth R van Wering; Anjo J P Veerman; Gritta E Janka-Schaub
Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(17):3262-8.
2003: Dorine Bresters; A J F Broekhuizen; Patricia Kaaijk; Glynn Faircloth; J Jimeno; G J L Kaspers
In vitro cytotoxicity of aplidin and crossresistance with other cytotoxic drugs in childhood leukemic and normal bone marrow and blood samples: a rational basis for clinical development.
Leukemia 2003;17(7):1338-43.
2003: G J L Kaspers
Targeted monoclonal antibody-based treatment of hematological malignancies.
Expert review of anticancer therapy 2003;3(3):253-5.
2003: Christian M Zwaan; Dirk Reinhardt; Selim Corbacioglu; Elisabeth R van Wering; Jos P M Bökkerink; Wim J E Tissing; Ulf Samuelsson; Jay Feingold; Ursula Creutzig; G J L Kaspers
Gemtuzumab ozogamicin: first clinical experiences in children with relapsed/refractory acute myeloid leukemia treated on compassionate-use basis.
Blood 2003;101(10):3868-71.
2003: Patricia Kaaijk; G J L Kaspers; Elisabeth R van Wering; GJ Broekema; Anne H Loonen; Karel Hählen; Kjeld Schmiegelow; Gritta E Janka-Schaub; Günter Henze; Ursula Creutzig; Anjo J P Veerman
Cell proliferation is related to in vitro drug resistance in childhood acute leukaemia.
British journal of cancer 2003;88(5):775-81.
2003: Eric G Haarman; G J L Kaspers; Anjo J P Veerman
Glucocorticoid resistance in childhood leukaemia: mechanisms and modulation.
British journal of haematology 2003;120(6):919-29.
2003: Clasina L Van der Wilt; Judith R Kroep; Willem J P Loves; Marianne G Rots; Cees J van Groeningen; G J L Kaspers; Godefridus J Peters
Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cell lines, liver metastases and normal liver.
European journal of cancer (Oxford, England : 1990) 2003;39(5):691-7.
2003: Jan Hendrik Hooijberg; Godefridus J Peters; Yehuda G Assaraf; Ietje Kathmann; David G Priest; Marlene A Bunni; Anjo J P Veerman; George L Scheffer; G J L Kaspers; Gerrit Jansen
The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.
Biochemical pharmacology 2003;65(5):765-71.
2003: Patricia Kaaijk; Antoinette Y N Schouten-Van Meeteren; Ben Slotman; G J L Kaspers
Past, current and future protocols for combined modality therapy in childhood medulloblastoma.
Expert review of anticancer therapy 2003;3(1):79-90.
2003: Christian M Zwaan; Dirk Reinhardt; H Jürgens; Dieuwke R Huismans; Karel Hählen; O P Smith; A Biondi; E R van Wering; J Feingold; G J L Kaspers
Gemtuzumab ozogamicin in pediatric CD33-positive acute lymphoblastic leukemia: first clinical experiences and relation with cellular sensitivity to single agent calicheamicin.
Leukemia 2003;17(2):468-70.
2003: G J L Kaspers; Anjo J P Veerman
Clinical significance of cellular drug resistance in childhood leukemia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;161():196-220.
2002: Christian M Zwaan; G J L Kaspers; Rob Pieters; Karel Hählen; Dieuwke R Huismans; Martin Zimmermann; Jochen Harbott; Rosalyn M Slater; Ursula Creutzig; Anjo J P Veerman
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.
Blood 2002;100(9):3352-60.
2002: Eric G Haarman; G J L Kaspers; Rob Pieters; M M A Rottier; Monique L den Boer; Gritta E Janka-Schaub; Anjo J P Veerman
In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37 degrees C, but not with affinity determined at room temperature.
Leukemia 2002;16(9):1882-4.
2002: V de Haas; G J L Kaspers; L Oosten; Dorine Bresters; R Pieters; V H J van der Velden; Elisabeth R van Wering; H van den Berg; C Ellen van der Schoot
Is there a relationship between in vitro drug resistance and level of minimal residual disease as detected by polymerase chain reaction at the end of induction therapy in childhood acute lymphoblastic leukaemia?
British journal of haematology 2002;118(4):1190-1.
2002: Dorine Bresters; Angelino C W Reus; Anjo J P Veerman; Elisabeth R van Wering; Anna van der Does-van den Berg; G J L Kaspers
Congenital leukaemia: the Dutch experience and review of the literature.
British journal of haematology 2002;117(3):513-24.
2002: Jeffrey W Taub; Larry H Matherly; Yaddanapudi Ravindranath; G J L Kaspers; M G Rots; C H Zantwijk
Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood acute lymphoblastic leukemia.
Leukemia 2002;16(4):764-5.
2002: Christian M Zwaan; G J L Kaspers; Rob Pieters; Karel Hählen; Gritta E Janka-Schaub; Christina H van Zantwijk; Dieuwke R Huismans; Esther de Vries; Marianne G Rots; Godefridus J Peters; Gerrit Jansen; Ursula Creutzig; Anjo J P Veerman
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.
Blood 2002;99(1):245-51.
2001: Kjeld Schmiegelow; Charlotte Nyvold; Jeanette Seyfarth; Rob Pieters; M M A Rottier; N Knabe; lars peter ryder; Hans O Madsen; Arne Svejgaard; G J L Kaspers
Post-induction residual leukemia in childhood acute lymphoblastic leukemia quantified by PCR correlates with in vitro prednisolone resistance.
Leukemia 2001;15(7):1066-71.
2001: G J L Kaspers
4th international symposium on leukemia and lymphoma--molecular pharmacology and new treatment modalities. VU Medical Center, Amsterdam, The Netherlands, 7-10 March 2001.
Expert review of anticancer therapy 2001;1(1):9-11.
2001: Marianne G Rots; Rob Pieters; Gerrit Jansen; G J L Kaspers; Christina H van Zantwijk; Paul Noordhuis; Daphne Voorn; Elisabeth R van Wering; Ursula Creutzig; Anjo J P Veerman; Godefridus J Peters
A possible role for methotrexate in the treatment of childhood acute myeloid leukaemia, in particular for acute monocytic leukaemia.
European journal of cancer (Oxford, England : 1990) 2001;37(4):492-8.
2000: Christian M Zwaan; G J L Kaspers; Rob Pieters; NL Ramakers-van Woerden; Monique L den Boer; R Wünsche; M M A Rottier; Karel Hählen; Elisabeth R van Wering; Gritta E Janka-Schaub; Ursula Creutzig; Anjo J P Veerman
Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia.
Blood 2000;96(8):2879-86.
2000: Marianne G Rots; Rob Pieters; G J L Kaspers; Anjo J P Veerman; Godefridus J Peters; Gerrit Jansen
Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukaemia.
British journal of haematology 2000;110(4):791-800.
2000: Angelika Dübbers; Gudrun Würthwein; Hans-Joachim Müller; Petra Schulze-Westhoff; M Winkelhorst; E Kurzknabe; Claudia Lanvers; Rob Pieters; G J L Kaspers; Ursula Creutzig; J Ritter; Joachim Boos
Asparagine synthetase activity in paediatric acute leukaemias: AML-M5 subtype shows lowest activity.
British journal of haematology 2000;109(2):427-9.
1999: Marianne G Rots; Rob Pieters; Godefridus J Peters; Christina H van Zantwijk; Robert Mauritz; Paul Noordhuis; James Willey; Karel Hählen; Ursula Creutzig; Gritta E Janka-Schaub; G J L Kaspers; Anjo J P Veerman; Gerrit Jansen
Circumvention of methotrexate resistance in childhood leukemia subtypes by rationally designed antifolates.
Blood 1999;94(9):3121-8.
1999: Gajja S Salomons; Lou A Smets; Manon Verwijs-Janssen; A A Hart; Eric G Haarman; G J L Kaspers; E V Wering; A V Der Does-Van Den Berg; Willem A Kamps
Bcl-2 family members in childhood acute lymphoblastic leukemia: relationships with features at presentation, in vitro and in vivo drug response and long-term clinical outcome.
Leukemia 1999;13(10):1574-80.
1999: G J L Kaspers; Christian M Zwaan; Anjo J P Veerman; Marianne G Rots; Rob Pieters; P Bucsky; M Domula; Ulrich Göbel; N Graf; W Havers; Norbert Jorch; K Kabisch; Hans J Spaar; Jörg Ritter; Ursula Creutzig
Cellular drug resistance in acute myeloid leukemia: literature review and preliminary analysis of an ongoing collaborative study.
Klinische Pädiatrie 1999;211(4):239-44.
1999: A E Duyn; G J L Kaspers; Rob Pieters; Christina H van Zantwijk; GJ Broekema; Karel Hählen; Anjo J P Veerman
Effects of interleukin 3, interleukin 7, and B-cell growth factor on proliferation and drug resistance in vitro in childhood acute lymphoblastic leukemia.
Annals of hematology 1999;78(4):163-71.
1999: Marianne G Rots; Rob Pieters; Godefridus J Peters; Paul Noordhuis; Christina H van Zantwijk; G J L Kaspers; Karel Hählen; Ursula Creutzig; Anjo J P Veerman; Gerrit Jansen
Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia.
Blood 1999;93(5):1677-83.
1999: Monique L den Boer; Rob Pieters; Karin M Kazemier; Gritta E Janka-Schaub; Günter Henze; Ursula Creutzig; G J L Kaspers; Pamela R Kearns; Andrew G Hall; Andrew D J Pearson; Anjo J P Veerman
Different expression of glutathione S-transferase alpha, mu and pi in childhood acute lymphoblastic and myeloid leukaemia.
British journal of haematology 1999;104(2):321-7.
1999: Marianne G Rots; Rob Pieters; G J L Kaspers; Christina H van Zantwijk; Paul Noordhuis; Robert Mauritz; Anjo J P Veerman; Gerrit Jansen; Godefridus J Peters
Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
Blood 1999;93(3):1067-74.
1999: I R Hegge; G J L Kaspers; Marianne G Rots; Gerrit Jansen; Rob Pieters; Anjo J P Veerman
Lack of cross-resistance between prednisolone and methotrexate in childhood acute lymphoblastic leukemia? A preliminary analysis.
Advances in experimental medicine and biology 1999;457():551-5.
1999: G J L Kaspers; Christian M Zwaan; Rob Pieters; Anjo J P Veerman
Cellular drug resistance in childhood acute myeloid leukemia. A mini-review with emphasis on cell culture assays.
Advances in experimental medicine and biology 1999;457():415-21.
1999: Rob Pieters; G J L Kaspers; NL Ramakers-van Woerden; Monique L den Boer; Marianne G Rots; Christian M Zwaan; Eric G Haarman; Anjo J P Veerman
Resistance testing and mechanisms of resistance in childhood leukemia. Studies from Amsterdam.
Advances in experimental medicine and biology 1999;457():391-5.
1999: Eric G Haarman; G J L Kaspers; Rob Pieters; Christina H van Zantwijk; GJ Broekema; Karel Hählen; Anjo J P Veerman
BCL-2 expression in childhood leukemia versus spontaneous apoptosis, drug induced apoptosis, and in vitro drug resistance.
Advances in experimental medicine and biology 1999;457():325-33.
1998: Rob Pieters; Monique L den Boer; M Durian; G Janka; Kjeld Schmiegelow; G J L Kaspers; Elisabeth R van Wering; Anjo J P Veerman
Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants.
Leukemia 1998;12(9):1344-8.
1998: G J L Kaspers; Rob Pieters; Christina H van Zantwijk; Elisabeth R van Wering; Anna van der Does-van den Berg; Anjo J P Veerman
Prednisolone resistance in childhood acute lymphoblastic leukemia: vitro-vivo correlations and cross-resistance to other drugs.
Blood 1998;92(1):259-66.
1998: Monique L den Boer; Rob Pieters; Karin M Kazemier; M M A Rottier; Christian M Zwaan; G J L Kaspers; Gritta E Janka-Schaub; Günter Henze; Ursula Creutzig; Rik J Scheper; Anjo J P Veerman
Relationship between major vault protein/lung resistance protein, multidrug resistance-associated protein, P-glycoprotein expression, and drug resistance in childhood leukemia.
Blood 1998;91(6):2092-8.
1997: G J L Kaspers; Anjo J P Veerman; Rob Pieters; Christina H van Zantwijk; Lou A Smets; Elisabeth R van Wering; Anna van der Does-van den Berg
In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia.
Blood 1997;90(7):2723-9.
1997: Rob Pieters; E Klumper; G J L Kaspers; Anjo J P Veerman
Everything you always wanted to know about cellular drug resistance in childhood acute lymphoblastic leukemia.
Critical reviews in oncology/hematology 1997;25(1):11-26.
1996: G J L Kaspers; Anjo J P Veerman; C Popp-Snijders; M Lomecky; Christina H van Zantwijk; L M Swinkels; Elisabeth R van Wering; Rob Pieters
Comparison of the antileukemic activity in vitro of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia.
Medical and pediatric oncology 1996;27(2):114-21.
1996: G J L Kaspers; Anjo J P Veerman; Elisabeth R van Wering; B E Van Der Linden-Schrever; Christina H van Zantwijk; Anna van der Does-van den Berg; Rob Pieters
Prognostic significance of peanut agglutinin binding in childhood acute lymphoblastic leukemia.
Leukemia 1996;10(4):675-81.
1995: E Klumper; Rob Pieters; Anjo J P Veerman; D R Huismans; A H Loonen; Karel Hählen; G J L Kaspers; Elisabeth R van Wering; R Hartmann; G Henze
In vitro cellular drug resistance in children with relapsed/refractory acute lymphoblastic leukemia.
Blood 1995;86(10):3861-8.
1995: G J L Kaspers; Rob Pieters; Christina H van Zantwijk; Elisabeth R van Wering; Anjo J P Veerman
Clinical and cell biological features related to cellular drug resistance of childhood acute lymphoblastic leukemia cells.
Leukemia & lymphoma 1995;19(5-6):407-16.
1995: E Klumper; Rob Pieters; G J L Kaspers; D R Huismans; A H Loonen; M M A Rottier; Elisabeth R van Wering; Anna van der Does-van den Berg; Karel Hählen; Ursula Creutzig
In vitro chemosensitivity assessed with the MTT assay in childhood acute non-lymphoblastic leukemia.
Leukemia 1995;9(11):1864-9.
1995: E Klumper; G Giaccone; Rob Pieters; G Broekema; J van Ark-Otte; Elisabeth R van Wering; G J L Kaspers; Anjo J P Veerman
Topoisomerase II alpha gene expression in childhood acute lymphoblastic leukemia.
Leukemia 1995;9(10):1653-60.
1995: G J L Kaspers; Anjo J P Veerman; Rob Pieters; I Van Zantwijk; Karel Hählen; Elisabeth R van Wering
Drug combination testing in acute lymphoblastic leukemia using the MTT assay.
Leukemia research 1995;19(3):175-81.
1995: G J L Kaspers; Lou A Smets; Rob Pieters; Christina H van Zantwijk; Elisabeth R van Wering; Anjo J P Veerman
Favorable prognosis of hyperdiploid common acute lymphoblastic leukemia may be explained by sensitivity to antimetabolites and other drugs: results of an in vitro study.
Blood 1995;85(3):751-6.
1994: G J L Kaspers; Anjo J P Veerman; Rob Pieters; G J Broekema; D R Huismans; Karin M Kazemier; A H Loonen; M A Rottier; Christina H van Zantwijk; Karel Hählen
Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay.
British journal of cancer 1994;70(6):1047-52.
1994: G J L Kaspers; G Kardos; Rob Pieters; Christina H van Zantwijk; E Klumper; Karel Hählen; F C de Waal; Elisabeth R van Wering; Anjo J P Veerman
Different cellular drug resistance profiles in childhood lymphoblastic and non-lymphoblastic leukemia: a preliminary report.
Leukemia 1994;8(7):1224-9.
1994: Rob Pieters; G J L Kaspers; E Klumper; Elisabeth R van Wering; Anna van der Does-van den Berg; Anjo J P Veerman
[Clinical relevance of resistance against cytostatic agents in children with leukemia].
Nederlands tijdschrift voor geneeskunde 1994;138(14):706-12.
1994: G J L Kaspers; Rob Pieters; E Klumper; F C De Waal; Anjo J P Veerman
Glucocorticoid resistance in childhood leukemia.
Leukemia & lymphoma 1994;13(3-4):187-201.
1994: Rob Pieters; G J L Kaspers; E Klumper; Anjo J P Veerman
Clinical relevance of in vitro drug resistance testing in childhood acute lymphoblastic leukemia: the state of the art.
Medical and pediatric oncology 1994;22(5):299-308.
1994: Anjo J P Veerman; G J L Kaspers; Rob Pieters
Cellular drug resistance in childhood leukemia.
Annals of hematology 1994;69 Suppl 1():S31-4.
1993: Rob Pieters; G J L Kaspers; Elisabeth R van Wering; D R Huismans; A H Loonen; Karel Hählen; Anjo J P Veerman
Cellular drug resistance profiles that might explain the prognostic value of immunophenotype and age in childhood acute lymphoblastic leukemia.
Leukemia 1993;7(3):392-7.
1993: G J L Kaspers; Rob Pieters; E Klumper; F C de Waal; Anjo J P Veerman
[The treatment of recurrence in children with acute lymphatic leukemia. Current results and various developments].
Tijdschrift voor kindergeneeskunde 1993;61(1):1-7.
1993: Rob Pieters; G J L Kaspers; Elisabeth R van Wering; D R Huismans; A H Loonen; Karel Hählen; Anjo J P Veerman
Cellular drug sensitivity of immunophenotypic subgroups of childhood acute lymphoblastic leukemia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():249-56.
1991: G J L Kaspers; Rob Pieters; Christina H van Zantwijk; P A De Laat; F C De Waal; Elisabeth R van Wering; Anjo J P Veerman
In vitro drug sensitivity of normal peripheral blood lymphocytes and childhood leukaemic cells from bone marrow and peripheral blood.
British journal of cancer 1991;64(3):469-74.
1991: G J L Kaspers; Wouter Kamphorst; M van de Graaff; H A van Alphen; Anjo J P Veerman
Primary spinal epidural extraosseous Ewing's sarcoma.
Cancer 1991;68(3):648-54.