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Moustapha Kassem

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Patrick Quint; Ming Ruan; Jennifer J Westendorf; Moustapha Kassem; Sundeep Khosla; Larry Pederson; Merry Jo Oursler
Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways.
May Al-Nbaheen; Amel Bouslimi; Moustapha Kassem; Matthias Megges; Alessandro Prigione; vishnubalaji radhakrishnan; Christian Regenbrecht; Dalia Ali; Fawzi Al-Jassir; Abdullah Aldahmash
Human stromal (mesenchymal) stem cells from bone marrow, adipose tissue and skin exhibit differences in molecular phenotype and differentiation potential.
Hardee J Sabir; Blagoy Blagoev; Linda Harkness; Adiba Isa; Moustapha Kassem; Jan Nehlin; Tatyana A Prokhorova; Diyako Qanie; Torben Barington
Separate developmental programs for HLA-A and -B cell surface expression during differentiation from embryonic stem cells to lymphocytes, adipocytes and osteoblasts.

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2013: Patrick Quint; Ming Ruan; Jennifer J Westendorf; Moustapha Kassem; Sundeep Khosla; Larry Pederson; Merry Jo Oursler
Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways.
The Journal of biological chemistry 2013;288(8):5398-406.
2013: May Al-Nbaheen; Amel Bouslimi; Moustapha Kassem; Matthias Megges; Alessandro Prigione; vishnubalaji radhakrishnan; Christian Regenbrecht; Dalia Ali; Fawzi Al-Jassir; Abdullah Aldahmash
Human stromal (mesenchymal) stem cells from bone marrow, adipose tissue and skin exhibit differences in molecular phenotype and differentiation potential.
Stem cell reviews 2013;9(1):32-43.
2013: Hardee J Sabir; Blagoy Blagoev; Linda Harkness; Adiba Isa; Moustapha Kassem; Jan Nehlin; Tatyana A Prokhorova; Diyako Qanie; Torben Barington
Separate developmental programs for HLA-A and -B cell surface expression during differentiation from embryonic stem cells to lymphocytes, adipocytes and osteoblasts.
PloS one 2013;8(1):e54366.
2012: Jorge S Burns; Giulia Grisendi; Moustapha Kassem; Akmal Safwat; Massimo Dominici
Sarcomas as a mise en abyme of mesenchymal stem cells: exploiting interrelationships for cell mediated anticancer therapy.
Cancer letters 2012;325(1):1-10.
2012: Amer Mahmood; Basem M Abdallah; Abdullah Aldahmash; May S Al-Nbaheen; Mona Elsafadi; Linda Harkness; Moustapha Kassem
Derivation of stromal (skeletal and mesenchymal) stem-like cells from human embryonic stem cells.
Stem cells and development 2012;21(17):3114-24.
2012: Elizabeth J Wright; Kelly A Farrell; Moustapha Kassem; Andrew L Lewis; Nadim Malik; Christine Wallrapp; Cathy M Holt
Encapsulated glucagon-like peptide-1-producing mesenchymal stem cells have a beneficial effect on failing pig hearts.
Stem cells translational medicine 2012;1(10):759-69.
2012: Lars P Kristensen; Maria Overbeck Nielsen; Diyako W Qanie; Li Chen; Moustapha Kassem; Irina Kratchmarova; Jens S Andersen
Temporal profiling and pulsed SILAC labeling identify novel secreted proteins during ex vivo osteoblast differentiation of human stromal stem cells.
Molecular & cellular proteomics : MCP 2012;11(10):989-1007.
2012: Linda Harkness; Jonas Beermann; Sergey I Bozhevolnyi; Sergey M Novikov; Moustapha Kassem
Identification of abnormal stem cells using Raman spectroscopy.
Stem cells and development 2012;21(12):2152-9.
2012: Oleksandra Karpiuk; Moustapha Kassem; Annekatrin König; Frank Kramer; Zeynab Najafova; Andrei Shchebet; Halyna Shcherbata; Mikael Simons; Nicolas Snaidero; Tanja Vogel; Yvonne Begus-Nahrmann; Tim Beissbarth; Christina Galonska; Magali Hennion; Steven A Johnsen
The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells.
Molecular cell 2012;46(5):705-13.
2012: Filippo P D'Andrea; Michael R Horsman; Moustapha Kassem; Jorge S Burns; Akmal Safwat; Jens Overgaard
Tumour microenvironment and radiation response in sarcomas originating from tumourigenic human mesenchymal stem cells.
International journal of radiation biology 2012;88(6):457-65.
2012: Hamid Saeed; Hanna Taipaleenmäki; Basem M Abdallah; Abdullah M Aldahmash; Moustapha Kassem
Mouse embryonic fibroblasts (MEF) exhibit a similar but not identical phenotype to bone marrow stromal stem cells (BMSC).
Stem cell reviews 2012;8(2):318-28.
2012: Filippo P D'Andrea; Michael R Horsman; Moustapha Kassem; Jens Overgaard; Akmal Safwat
Tumourigenicity and radiation resistance of mesenchymal stem cells.
Acta oncologica (Stockholm, Sweden) 2012;51(5):669-79.
2012: Hanna Taipaleenmäki; Sakari Kauppinen; Lea Bjerre Hokland; Li Chen; Moustapha Kassem
Mechanisms in endocrinology: micro-RNAs: targets for enhancing osteoblast differentiation and bone formation.
European journal of endocrinology / European Federation of Endocrine Societies 2012;166(3):359-71.
2012: Christiane L Elseberg; Moustapha Kassem; Matthias Kraume; Jasmin Leber; Denise Salzig; Christine Wallrapp; Peter Czermak
Microcarrier-based expansion process for hMSCs with high vitality and undifferentiated characteristics.
The International journal of artificial organs 2012;35(2):93-107.
2012: Hanna Taipaleenmäki; Li Chen; Linda Harkness; Moustapha Kassem; Kenneth H Larsen; Anna-Marja Säämänen; Basem M Abdallah
The crosstalk between transforming growth factor-β1 and delta like-1 mediates early chondrogenesis during embryonic endochondral ossification.
Stem cells (Dayton, Ohio) 2012;30(2):304-13.
2012: Basem M Abdallah; Moustapha Kassem
New factors controlling the balance between osteoblastogenesis and adipogenesis.
Bone 2012;50(2):540-5.
2012: Muwan Chen; San Hein; Moustapha Kassem; Jørgen Kjems; Dang Q S Le; Pengcheng Li; Jens V Nygaard; Flemming Besenbacher; Cody Bünger
Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release.
International journal of nanomedicine 2012;7():4285-97.
2012: Alin Andries; Kirsten Hørder; Andreas Niemeier; René K Støving; Anna-Maria Wolf; Basem M Abdallah; Moustapha Kassem
Serum levels of fetal antigen 1 in extreme nutritional States.
ISRN endocrinology 2012;2012():592648.
2012: Linda Harkness; Moustapha Kassem; Tatyana A Prokhorova; Blagoy Blagoev
Stable isotope labelling with amino acids in cell culture for human embryonic stem cell proteomic analysis.
Methods in molecular biology (Clifton, N.J.) 2012;873():297-305.
2012: Linda Harkness; Moustapha Kassem
Procedures for derivation and characterisation of human embryonic stem cells from Odense, Denmark.
Methods in molecular biology (Clifton, N.J.) 2012;873():33-51.
2012: Simon Asbjørn Larsen; Moustapha Kassem; Suresh Is Rattan
Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells.
Chemistry Central journal 2012;6(1):18.
2011: Abdullah Aldahmash; May Al-Nbaheen; Mandana Haack-Sørensen; Linda Harkness; Basem M Abdallah; Moustapha Kassem
Human serum is as efficient as fetal bovine serum in supporting proliferation and differentiation of human multipotent stromal (mesenchymal) stem cells in vitro and in vivo.
Stem cell reviews 2011;7(4):860-8.
2011: Basem M Abdallah; Anne-Christine Bay-Jensen; Jean-Marie Delaissé; Patrick Garnero; Sundeep Khosla; Bhuma Srinivasan; Nadine C Tabassi; Moustapha Kassem
Estrogen inhibits Dlk1/FA1 production: a potential mechanism for estrogen effects on bone turnover.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(10):2548-51.
2011: Weimin Qiu; Li Chen; Moustapha Kassem
Activation of non-canonical Wnt/JNK pathway by Wnt3a is associated with differentiation fate determination of human bone marrow stromal (mesenchymal) stem cells.
Biochemical and biophysical research communications 2011;413(1):98-104.
2011: Li Chen; Abbas Jafari; Charlotte H Jensen; Jorge Laborda; Diyako Qanie; Anna-Marja Säämänen; Maria Luisa Nueda Sanz; Hanna Taipaleenmaki; Basem M Abdallah; Moustapha Kassem
Delta-like 1/fetal antigen-1 (Dlk1/FA1) is a novel regulator of chondrogenic cell differentiation via inhibition of the Akt kinase-dependent pathway.
The Journal of biological chemistry 2011;286(37):32140-9.
2011: Ditte C Andersen; Li Chen; Stan Gronthos; Charlotte H Jensen; Ole N Jensen; Angela Kortesidis; Irina Kratchmarova; Børge Teisner; Andrew C W Zannettino; Moustapha Kassem
Development of novel monoclonal antibodies that define differentiation stages of human stromal (mesenchymal) stem cells.
Molecules and cells 2011;32(2):133-42.
2011: Robert J Pignolo; Moustapha Kassem
Circulating osteogenic cells: implications for injury, repair, and regeneration.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(8):1685-93.
2011: Catarina Limbert; Günter Päth; Veit Rothhammer; Regina Ebert; Franz Jakob; Moustapha Kassem; Jochen Seufert
PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages.
Cytotherapy 2011;13(7):802-13.
2011: Morten Frost; Fatma Gossiel; Stinus Hansen; Moustapha Kassem; Wim Van Hul; Tom Andersen; Jens Bollerslev; Ana Munoz; Kim Brixen
Levels of serotonin, sclerostin, bone turnover markers as well as bone density and microarchitecture in patients with high-bone-mass phenotype due to a mutation in Lrp5.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(8):1721-8.
2011: Jorge S Burns; Moustapha Kassem
The best bone marrow stromal cell for therapy is … 'yellow'.
Cytotherapy 2011;13(6):644-6.
2011: Pierre J Marie; Moustapha Kassem
Osteoblasts in osteoporosis: past, emerging, and future anabolic targets.
European journal of endocrinology / European Federation of Endocrine Societies 2011;165(1):1-10.
2011: Hamid Saeed; Weimin Qiu; Basem M Abdallah; Michael Amling; Philip Catala-Lehnen; Nicholas Ditzel; Moustapha Kassem
Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(7):1494-505.
2011: Basem M Abdallah; Michael Amling; Nicholas Ditzel; Adiba Isa; Jorge Laborda; Amer Mahmood; María José Ruiz-Hidalgo; Arndt F Schilling; Gunnhildur A Traustadottir; Moustapha Kassem
DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(7):1457-71.
2011: Filippo P D'Andrea; Laurant Gautier; Moustapha Kassem; Jens Overgaard; Akmal Safwat; Michael R Horsman
Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;99(3):373-8.
2011: Lea Bjerre; Cody Bünger; Anette Baatrup; Moustapha Kassem; Tina Mygind
Flow perfusion culture of human mesenchymal stem cells on coralline hydroxyapatite scaffolds with various pore sizes.
Journal of biomedical materials research. Part A 2011;97(3):251-63.
2011: Ariane Tormin; Ou Li; Jan Claas Brune; Stuart Walsh; Birgit Schütz; Mats Ehinger; Nicholas Ditzel; Moustapha Kassem; Stefan Scheding
CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization.
Blood 2011;117(19):5067-77.
2011: A Dolatshahi-Pirouz; T H L Jensen; K Kolind; Cody Bünger; Moustapha Kassem; Morten Foss; Flemming Besenbacher
Cell shape and spreading of stromal (mesenchymal) stem cells cultured on fibronectin coated gold and hydroxyapatite surfaces.
Colloids and surfaces. B, Biointerfaces 2011;84(1):18-25.
2011: Muwan Chen; Dang Q S Le; Anette Baatrup; Jens V Nygaard; San Hein; Lea Bjerre; Moustapha Kassem; Xuenong Zou; Cody Bünger
Self-assembled composite matrix in a hierarchical 3-D scaffold for bone tissue engineering.
Acta biomaterialia 2011;7(5):2244-55.
2011: Tilde Eskildsen; Hanna Taipaleenmäki; Stenvang Jan; Basem M Abdallah; Nicholas Ditzel; Anne Yael Nossent; Mads Bak; Sakari Kauppinen; Moustapha Kassem
MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(15):6139-44.
2011: Hanna Taipaleenmäki; Basem M Abdallah; Abdullah AlDahmash; Anna-Marja Säämänen; Moustapha Kassem
Wnt signalling mediates the cross-talk between bone marrow derived pre-adipocytic and pre-osteoblastic cell populations.
Experimental cell research 2011;317(6):745-56.
2011: Moustapha Kassem; Pierre J Marie
Senescence-associated intrinsic mechanisms of osteoblast dysfunctions.
Aging cell 2011;10(2):191-7.
2011: Pierre J Marie; Moustapha Kassem
Extrinsic mechanisms involved in age-related defective bone formation.
The Journal of clinical endocrinology and metabolism 2011;96(3):600-9.
2011: Linda Harkness; Amer Mahmood; Nicholas Ditzel; Basem M Abdallah; Jens V Nygaard; Moustapha Kassem
Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential.
Bone 2011;48(2):231-41.
2011: Jorge S Burns; Helle Christiansen; Jens S Andersen; Lars P Kristensen; Malthe Kristiansen; Kenneth H Larsen; Jan Nehlin; Maria O Nielsen; Moustapha Kassem
Decellularized matrix from tumorigenic human mesenchymal stem cells promotes neovascularization with galectin-1 dependent endothelial interaction.
PloS one 2011;6(7):e21888.
2011: Kristoffer T G Rigbolt; Tatyana A Prokhorova; Vyacheslav Akimov; Jeanette Henningsen; Pia T Johansen; Irina Kratchmarova; Moustapha Kassem; Matthias Mann; Jesper V Olsen; Blagoy Blagoev
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
Science signaling 2011;4(164):rs3.
2010: Morten Ø Andersen; Jens V Nygaard; Jorge S Burns; Merete K Raarup; Jens R Nyengaard; Cody Bünger; Flemming Besenbacher; Kenneth A Howard; Moustapha Kassem; Jørgen Kjems
siRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(11):2018-27.
2010: Kenneth H Larsen; Tom E Andersen; Moustapha Kassem
[Bone and cartilage repair using stem cells].
Ugeskrift for laeger 2010;172(38):2616-9.
2010: Jorge Burns; Pernille L Rasmussen; Kenneth H Larsen; Henrik Daa Schrøder; Moustapha Kassem
Parameters in three-dimensional osteospheroids of telomerized human mesenchymal (stromal) stem cells grown on osteoconductive scaffolds that predict in vivo bone-forming potential.
Tissue engineering. Part A 2010;16(7):2331-42.
2010: Axel C P Diederichsen; Jacob E Møller; Per Thayssen; Lars Videbaek; Susanne G Saekmose; Torben Barington; Moustapha Kassem
Changes in left ventricular filling patterns after repeated injection of autologous bone marrow cells in heart failure patients.
Scandinavian cardiovascular journal : SCJ 2010;44(3):139-45.
2010: Signe Sparre Beck-Nielsen; Susanne Møller Pedersen; Moustapha Kassem; Lars Melholt Rasmussen
[Fibroblast growth factor 23--a phosphate regulating hormone].
Ugeskrift for laeger 2010;172(20):1521-7.
2010: Weimin Qiu; Yuhui Hu; Tom E Andersen; Abbas Jafari; Na Li; Wei Chen; Moustapha Kassem
Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP.
The Journal of biological chemistry 2010;285(19):14438-49.
2010: Linda Harkness; Iben Anne Rasmussen; Karin Erb; Moustapha Kassem
Derivation and characterisation of hESC lines from supernumerary embryos, experience from Odense, Denmark.
In vitro cellular & developmental biology. Animal 2010;46(3-4):259-68.
2010: Kenneth H Larsen; Casper Frederiksen; Jorge Burns; Basem M Abdallah; Moustapha Kassem
Identifying a molecular phenotype for bone marrow stromal cells with in vivo bone-forming capacity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(4):796-808.
2010: Morten Frost; Tom Erenskjold Andersen; Vijay Yadav; Kim Brixen; Gerard Karsenty; Moustapha Kassem
Patients with high-bone-mass phenotype owing to Lrp5-T253I mutation have low plasma levels of serotonin.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(3):673-5.
2010: David C E Kraft; Dorthe A Bindslev; Birte Melsen; Basem M Abdallah; Moustapha Kassem; Jenneke Klein-Nulend
Mechanosensitivity of dental pulp stem cells is related to their osteogenic maturity.
European journal of oral sciences 2010;118(1):29-38.
2010: Lothar Seefried; Sigrid Mueller-Deubert; Thomas Schwarz; Thomas Lind; Birgit Mentrup; Melanie Kober; Denitsa Docheva; Astrid Liedert; Moustapha Kassem; Anita Ignatius; Matthias Schieker; Lutz Claes; Winfried Wilke; Franz Jakob; Regina Ebert
A small scale cell culture system to analyze mechanobiology using reporter gene constructs and polyurethane dishes.
European cells & materials 2010;20():344-55.
2010: Jørn Henriksen; Marianne Stabell; Leonardo A. Meza-Zepeda; Silje Au Lauvrak; Moustapha Kassem; Ola Myklebost
Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells.
BMC cancer 2010;10():329.
2010: Adiba Isa; Jan O Nehlin; Hardee J Sabir; Tom E Andersen; Michael Gaster; Moustapha Kassem; Torben Barington
Impaired cell surface expression of HLA-B antigens on mesenchymal stem cells and muscle cell progenitors.
PloS one 2010;5(5):e10900.
2010: Thomas Jensen; Alireza Dolatshahi-Pirouz; Morten Foss; Jørgen Baas; Jette Lovmand; Mogens Duch; Finn Skou Pedersen; Moustapha Kassem; Cody Bünger; Kjeld Søballe; Flemming Besenbacher
Interaction of human mesenchymal stem cells with osteopontin coated hydroxyapatite surfaces.
Colloids and surfaces. B, Biointerfaces 2010;75(1):186-93.
2009: Linda Harkness; Hanna Taipaleenmaki; Amer Mahmood; Ulrik Frandsen; Anna-Marja Saamanen; Moustapha Kassem; Basem M Abdallah
Isolation and differentiation of chondrocytic cells derived from human embryonic stem cells using dlk1/FA1 as a novel surface marker.
Stem cell reviews 2009;5(4):353-68.
2009: Muwan Chen; Wenzhou Feng; Hui Cao; Lijin Zou; Chungui Chen; Anette Baatrup; Anne Bay Nielsen; Haisheng Li; Moustapha Kassem; Xuenong Zou; Cody Bünger
A traditional Chinese medicine formula extracts stimulate proliferation and inhibit mineralization of human mesenchymal stem cells in vitro.
Journal of ethnopharmacology 2009;125(1):75-82.
2009: Morten Gjerstorff; Jorge S Burns; Ole Nielsen; Moustapha Kassem; Henrik J Ditzel
Epigenetic modulation of cancer-germline antigen gene expression in tumorigenic human mesenchymal stem cells: implications for cancer therapy.
The American journal of pathology 2009;175(1):314-23.
2009: Sandra Rinne Dahl; Charlotte Ramstad Kleiveland; Moustapha Kassem; Tor Lea; Elsa Lundanes; Tyge Greibrokk
Determination of thromboxanes, leukotrienes and lipoxins using high-temperature capillary liquid chromatography-tandem mass spectrometry and on-line sample preparation.
Journal of chromatography. A 2009;1216(22):4648-54.
2009: Tatyana A Prokhorova; Kristoffer T G Rigbolt; Pia T Johansen; Jeanette Henningsen; Irina Kratchmarova; Moustapha Kassem; Blagoy Blagoev
Stable isotope labeling by amino acids in cell culture (SILAC) and quantitative comparison of the membrane proteomes of self-renewing and differentiating human embryonic stem cells.
Molecular & cellular proteomics : MCP 2009;8(5):959-70.
2009: Maik Stiehler; Cody Bünger; Anette Baatrup; Martin Lind; Moustapha Kassem; Tina Mygind
Effect of dynamic 3-D culture on proliferation, distribution, and osteogenic differentiation of human mesenchymal stem cells.
Journal of biomedical materials research. Part A 2009;89(1):96-107.
2009: Anne-Christine Bay-Jensen; Nadine C B Tabassi; Lene V Sondergaard; Thomas L Andersen; Frederik Dagnaes-Hansen; Patrick Garnero; Moustapha Kassem; Jean-Marie Delaissé
The response to oestrogen deprivation of the cartilage collagen degradation marker, CTX-II, is unique compared with other markers of collagen turnover.
Arthritis research & therapy 2009;11(1):R9.
2009: Basem M Abdallah; Moustapha Kassem
The use of mesenchymal (skeletal) stem cells for treatment of degenerative diseases: current status and future perspectives.
Journal of cellular physiology 2009;218(1):9-12.
2009: Tatyana A Prokhorova; Linda M Harkness; Ulrik Frandsen; Nicholas Ditzel; Henrik D Schrøder; Jorge Burns; Moustapha Kassem
Teratoma formation by human embryonic stem cells is site dependent and enhanced by the presence of Matrigel.
Stem cells and development 2009;18(1):47-54.
2008: Günter Lepperdinger; Regina Brunauer; Angelika Jamnig; Gerhard Laschober; Moustapha Kassem
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
Experimental gerontology 2008;43(11):1018-23.
2008: Jorge Burns; Basem M Abdallah; H D Schrøder; Moustapha Kassem
The histopathology of a human mesenchymal stem cell experimental tumor model: support for an hMSC origin for Ewing's sarcoma?
Histology and histopathology 2008;23(10):1229-40.
2008: Morten F Gjerstorff; Linda Harkness; Moustapha Kassem; Ulrik Frandsen; Ole Nielsen; Melissa Lutterodt; Kjeld Møllgård; Henrik J Ditzel
Distinct GAGE and MAGE-A expression during early human development indicate specific roles in lineage differentiation.
Human reproduction (Oxford, England) 2008;23(10):2194-201.
2008: Linda Harkness; Helle Christiansen; Jan Nehlin; Torben Barington; Jens S Andersen; Moustapha Kassem
Identification of a membrane proteomic signature for human embryonic stem cells independent of culture conditions.
Stem cell research 2008;1(3):219-27.
2008: Sandra Rinne Dahl; Charlotte Ramstad Kleiveland; Moustapha Kassem; Tor Lea; Elsa Lundanes; Tyge Greibrokk
Detecting pM concentrations of prostaglandins in cell culture supernatants by capillary SCX-LC-MS/MS.
Journal of separation science 2008;31(14):2627-33.
2008: Tine E Thingholm; Martin R Larsen; Christian R Ingrell; Moustapha Kassem; Ole N Jensen
TiO(2)-based phosphoproteomic analysis of the plasma membrane and the effects of phosphatase inhibitor treatment.
Journal of proteome research 2008;7(8):3304-13.
2008: Maik Stiehler; Martin Lind; Tina Mygind; Anette Baatrup; Alireza Dolatshahi-Pirouz; Haisheng Li; Morten Foss; Flemming Besenbacher; Moustapha Kassem; Cody Bünger
Morphology, proliferation, and osteogenic differentiation of mesenchymal stem cells cultured on titanium, tantalum, and chromium surfaces.
Journal of biomedical materials research. Part A 2008;86(2):448-58.
2008: Axel C P Diederichsen; Jacob E Møller; Per Thayssen; Anders B Junker; Lars Videbaek; Susanne G Saekmose; Torben Barington; Malthe Kristiansen; Moustapha Kassem
Effect of repeated intracoronary injection of bone marrow cells in patients with ischaemic heart failure the Danish stem cell study--congestive heart failure trial (DanCell-CHF).
European journal of heart failure 2008;10(7):661-7.
2008: S Post; Basem M Abdallah; J F Bentzon; Moustapha Kassem
Demonstration of the presence of independent pre-osteoblastic and pre-adipocytic cell populations in bone marrow-derived mesenchymal stem cells.
Bone 2008;43(1):32-9.
2008: Lea Bjerre; Cody E Bünger; Moustapha Kassem; Tina Mygind
Flow perfusion culture of human mesenchymal stem cells on silicate-substituted tricalcium phosphate scaffolds.
Biomaterials 2008;29(17):2616-27.
2008: Moustapha Kassem; Basem M Abdallah; Hamid Saeed
Osteoblastic cells: differentiation and trans-differentiation.
Archives of biochemistry and biophysics 2008;473(2):183-7.
2008: Charlotte Ramstad Kleiveland; Moustapha Kassem; Tor Lea
Human mesenchymal stem cell proliferation is regulated by PGE2 through differential activation of cAMP-dependent protein kinase isoforms.
Experimental cell research 2008;314(8):1831-8.
2008: Kirsten Grønbaek; Ulrik Ralfkiaer; Christina Dahl; Christoffer Hother; Jorge Burns; Moustapha Kassem; Jesper Worm; Elisabeth Ralfkiaer; Lene M Knudsen; Peter Hokland; Per Guldberg
Frequent hypermethylation of DBC1 in malignant lymphoproliferative neoplasms.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(5):632-8.
2008: Lijin Zou; Xuenong Zou; Li Chen; Haisheng Li; Tina Mygind; Moustapha Kassem; Cody Bünger
Effect of hyaluronan on osteogenic differentiation of porcine bone marrow stromal cells in vitro.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2008;26(5):713-20.
2008: Janne Prawitt; Andreas Niemeier; Moustapha Kassem; Ulrike Beisiegel; Joerg Heeren
Characterization of lipid metabolism in insulin-sensitive adipocytes differentiated from immortalized human mesenchymal stem cells.
Experimental cell research 2008;314(4):814-24.
2008: Basem M Abdallah; Nicholas Ditzel; Moustapha Kassem
Assessment of bone formation capacity using in vivo transplantation assays: procedure and tissue analysis.
Methods in molecular biology (Clifton, N.J.) 2008;455():89-100.
2008: Moustapha Kassem; Basem M Abdallah
Human bone-marrow-derived mesenchymal stem cells: biological characteristics and potential role in therapy of degenerative diseases.
Cell and tissue research 2008;331(1):157-63.
2007: Weimin Qiu; Tom E Andersen; Jens Bollerslev; Susanne Mandrup; Basem M Abdallah; Moustapha Kassem
Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(11):1720-31.
2007: Jacob F Bentzon; Claus S Sondergaard; Moustapha Kassem; Erling Falk
Smooth muscle cells healing atherosclerotic plaque disruptions are of local, not blood, origin in apolipoprotein E knockout mice.
Circulation 2007;116(18):2053-61.
2007: Ulrik Frandsen; Ann Dorte Porneki; Charlotte Floridon; Basem M Abdallah; Moustapha Kassem
Activin B mediated induction of Pdx1 in human embryonic stem cell derived embryoid bodies.
Biochemical and biophysical research communications 2007;362(3):568-74.
2007: Basem M Abdallah; Ming Ding; Charlotte H Jensen; Nicholas Ditzel; Allan Flyvbjerg; Thomas G Jensen; Frederik Dagnaes-Hansen; Jürg A Gasser; Moustapha Kassem
Dlk1/FA1 is a novel endocrine regulator of bone and fat mass and its serum level is modulated by growth hormone.
Endocrinology 2007;148(7):3111-21.
2007: Basem M Abdallah; Patrice Boissy; Qihua Tan; Jesper Dahlgaard; Gunnhildur A Traustadottir; Katarzyna Kupisiewicz; Jorge Laborda; Jean-Marie Delaisse; Moustapha Kassem
dlk1/FA1 regulates the function of human bone marrow mesenchymal stem cells by modulating gene expression of pro-inflammatory cytokines and immune response-related factors.
The Journal of biological chemistry 2007;282(10):7339-51.
2006: Jacob F Bentzon; Charlotte Weile; Claus S Sondergaard; Johnny Hindkjaer; Moustapha Kassem; Erling Falk
Smooth muscle cells in atherosclerosis originate from the local vessel wall and not circulating progenitor cells in ApoE knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2696-702.
2006: Basem M Abdallah; Mandana Haack-Sørensen; Trine Fink; Moustapha Kassem
Inhibition of osteoblast differentiation but not adipocyte differentiation of mesenchymal stem cells by sera obtained from aged females.
Bone 2006;39(1):181-8.
2006: Ivo Fierro-Monti; shabaz mohammed; Rune Matthiesen; Raffaela Santoro; Jorge Burns; David J Williams; Christopher G Proud; Moustapha Kassem; Ole N Jensen; Peter Roepstorff
Quantitative proteomics identifies Gemin5, a scaffolding protein involved in ribonucleoprotein assembly, as a novel partner for eukaryotic initiation factor 4E.
Journal of proteome research 2006;5(6):1367-78.
2006: Rune Nørgaard; Moustapha Kassem; Suresh Rattan
Heat shock-induced enhancement of osteoblastic differentiation of hTERT-immortalized mesenchymal stem cells.
Annals of the New York Academy of Sciences 2006;1067():443-7.
2006: Moustapha Kassem
Stem cells: potential therapy for age-related diseases.
Annals of the New York Academy of Sciences 2006;1067():436-42.
2006: Axel C P Diederichsen; Jacob E Møller; Malthe A M Kristiansen; Susanne Gjørup Saekmose; Torben Barington; Lars Videbaek; Moustapha Kassem; Per Thayssen
[Stem cell therapy in ischemic heart disease].
Ugeskrift for laeger 2006;168(11):1111-4.
2006: Nedime Serakinci; Stacey F Hoare; Moustapha Kassem; Stuart P Atkinson; Nicol Keith
Telomerase promoter reprogramming and interaction with general transcription factors in the human mesenchymal stem cell.
Regenerative medicine 2006;1(1):125-31.
2005: Patrice Boissy; Thomas L Andersen; Basem M Abdallah; Moustapha Kassem; Torben Plesner; Jean-Marie Delaissé
Resveratrol inhibits myeloma cell growth, prevents osteoclast formation, and promotes osteoblast differentiation.
Cancer research 2005;65(21):9943-52.
2005: Moustapha Kassem; Jorge Burns; Javier Garcia-Castro; Daniel Rubio Muñoz
Adult stem cells and cancer.
Cancer research 2005;65(20):9601; author reply 9601.
2005: Irina Kratchmarova; Blagoy Blagoev; Mandana Haack-Sorensen; Moustapha Kassem; Matthias Mann
Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation.
Science (New York, N.Y.) 2005;308(5727):1472-7.
2005: Jacob F Bentzon; Karin Stenderup; F D Hansen; H D Schroder; Basem M Abdallah; Thomas G Jensen; Moustapha Kassem
Tissue distribution and engraftment of human mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene.
Biochemical and biophysical research communications 2005;330(3):633-40.
2005: Jorge Burns; Basem M Abdallah; Per Guldberg; Jørgen Rygaard; Henrik Daa Schrøder; Moustapha Kassem
Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells.
Cancer research 2005;65(8):3126-35.
2005: Knud Bonnet Yderstraede; Moustapha Kassem; Claus Juhl
[Systemic vascular leak syndrome].
Ugeskrift for laeger 2005;167(15):1648-9.
2005: Kim Brixen; Bo Abrahamsen; Moustapha Kassem; Leif Mosekilde
[Pharmacological treatment of osteitis deformans (Paget's bone disease)].
Ugeskrift for laeger 2005;167(9):1009-12.
2005: Basem M Abdallah; Lis Stilgren; Nis Nissen; Moustapha Kassem; Hans R I Jørgensen; Bo Abrahamsen
Increased RANKL/OPG mRNA ratio in iliac bone biopsies from women with hip fractures.
Calcified tissue international 2005;76(2):90-7.
2005: Basem M Abdallah; Mandana Haack-Sørensen; Jorge Burns; Birgitte Elsnab; Franz Jakob; Peter Hokland; Moustapha Kassem
Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite [corrected] extensive proliferation.
Biochemical and biophysical research communications 2005;326(3):527-38.
2004: Moustapha Kassem; Malthe M Kristiansen; Basem M Abdallah
Mesenchymal stem cells: cell biology and potential use in therapy.
Basic & clinical pharmacology & toxicology 2004;95(5):209-14.
2004: Nedime Serakinci; Per Guldberg; Jorge Burns; Basem M Abdallah; Henrik Schrødder; Thomas Jensen; Moustapha Kassem
Adult human mesenchymal stem cell as a target for neoplastic transformation.
Oncogene 2004;23(29):5095-8.
2004: Moustapha Kassem; Basem M Abdallah; Zentao Yu; Nicholas Ditzel; Jorge Burns
The use of hTERT-immortalized cells in tissue engineering.
Cytotechnology 2004;45(1-2):39-46.
2004: Basem M Abdallah; Charlotte H Jensen; Gloria Gutierrez; Robert G Q Leslie; Thomas G Jensen; Moustapha Kassem
Regulation of human skeletal stem cells differentiation by Dlk1/Pref-1.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(5):841-52.
2004: Just Justesen; Leif Mosekilde; Megan Holmes; Karin Stenderup; Jürg Gasser; John J Mullins; Jonathan R Seckl; Moustapha Kassem
Mice deficient in 11beta-hydroxysteroid dehydrogenase type 1 lack bone marrow adipocytes, but maintain normal bone formation.
Endocrinology 2004;145(4):1916-25.
2004: Just Justesen; Steen Pedersen; Karin Stenderup; Moustapha Kassem
Subcutaneous adipocytes can differentiate into bone-forming cells in vitro and in vivo.
Tissue engineering 2004;10(3-4):381-91.
2004: Moustapha Kassem
Mesenchymal stem cells: biological characteristics and potential clinical applications.
Cloning and stem cells 2004;6(4):369-74.
2004: Trine Fink; Lisbeth Abildtrup; Kirsten Fogd; Basem M Abdallah; Moustapha Kassem; Peter Ebbesen; Vladimir Zachar
Induction of adipocyte-like phenotype in human mesenchymal stem cells by hypoxia.
Stem cells (Dayton, Ohio) 2004;22(7):1346-55.
2004: Karin Stenderup; Cecilia Rosada; Just Justesen; T Al-Soubky; Frederik Dagnaes-Hansen; Moustapha Kassem
Aged human bone marrow stromal cells maintaining bone forming capacity in vivo evaluated using an improved method of visualization.
Biogerontology 2004;5(2):107-18.
2003: Jacob Fog Bentzon; Erling Falk; Moustapha Kassem
[Regeneration of myocardium by stem cell therapy. Historical and biological perspective].
Ugeskrift for laeger 2003;165(50):4855-9.
2003: Moustapha Kassem; Jens Kastrup; Gitte Olsen; Hans Erik Johnsen
[Mesenchymal stem cell therapy--the key to regenerative medicine?].
Ugeskrift for laeger 2003;165(50):4852-5.
2003: Karin Stenderup; Just Justesen; Christian Clausen; Moustapha Kassem
Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells.
Bone 2003;33(6):919-26.
2003: Cecilia Rosada; Just Justesen; D Melsvik; P Ebbesen; Moustapha Kassem
The human umbilical cord blood: a potential source for osteoblast progenitor cells.
Calcified tissue international 2003;72(2):135-42.
2002: Just Justesen; Karin Stenderup; Erik F Eriksen; Moustapha Kassem
Maintenance of osteoblastic and adipocytic differentiation potential with age and osteoporosis in human marrow stromal cell cultures.
Calcified tissue international 2002;71(1):36-44.
2002: Janne Simonsen; Cecilia Rosada; Nedime Serakinci; Just Justesen; Karin Stenderup; Suresh Rattan; Thomas G Jensen; Moustapha Kassem
Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells.
Nature biotechnology 2002;20(6):592-6.
2002: M Kveiborg; Allan Flyvbjerg; Moustapha Kassem
Synergistic effects of 1,25-Dihydroxyvitamin D3 and TGF-beta1 on the production of insulin-like growth factor binding protein 3 in human bone marrow stromal cell cultures.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2002;110(5):410-4.
2001: Just Justesen; Karin Stenderup; Moustapha Kassem
[Mesenchymal stem cells. Potential use in cell and gene therapy of bone loss caused by aging and osteoporosis].
Ugeskrift for laeger 2001;163(40):5491-5.
2001: L Tornvig; Leif Mosekilde; Just Justesen; E Falk; Moustapha Kassem
Troglitazone treatment increases bone marrow adipose tissue volume but does not affect trabecular bone volume in mice.
Calcified tissue international 2001;69(1):46-50.
2001: Karin Stenderup; Just Justesen; Erik F Eriksen; Suresh Rattan; Moustapha Kassem
Number and proliferative capacity of osteogenic stem cells are maintained during aging and in patients with osteoporosis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(6):1120-9.
2001: M Kveiborg; Allan Flyvbjerg; EF Eriksen; Moustapha Kassem
Transforming growth factor-beta1 stimulates the production of insulin-like growth factor-I and insulin-like growth factor-binding protein-3 in human bone marrow stromal osteoblast progenitors.
The Journal of endocrinology 2001;169(3):549-61.
2001: M Kveiborg; Allan Flyvbjerg; EF Eriksen; Moustapha Kassem
1,25-Dihydroxyvitamin D3 stimulates the production of insulin-like growth factor-binding proteins-2, -3 and -4 in human bone marrow stromal cells.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(5):549-57.
2001: M Kveiborg; Suresh Rattan; Brian F C Clark; EF Eriksen; Moustapha Kassem
Treatment with 1,25-dihydroxyvitamin D3 reduces impairment of human osteoblast functions during cellular aging in culture.
Journal of cellular physiology 2001;186(2):298-306.
2001: Just Justesen; Karin Stenderup; E N Ebbesen; Leif Mosekilde; T Steiniche; Moustapha Kassem
Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis.
Biogerontology 2001;2(3):165-71.
2000: M Kveiborg; Allan Flyvbjerg; Suresh Rattan; Moustapha Kassem
Changes in the insulin-like growth factor-system may contribute to in vitro age-related impaired osteoblast functions.
Experimental gerontology 2000;35(8):1061-74.
2000: Moustapha Kassem; M Kveiborg; EF Eriksen
Production and action of transforming growth factor-beta in human osteoblast cultures: dependence on cell differentiation and modulation by calcitriol.
European journal of clinical investigation 2000;30(5):429-37.
2000: Mette Christiansen; M Kveiborg; Moustapha Kassem; Brian F C Clark; Suresh Rattan
CBFA1 and topoisomerase I mRNA levels decline during cellular aging of human trabecular osteoblasts.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(4):B194-200.
1999: M Kveiborg; Leif Mosekilde; EF Eriksen; Moustapha Kassem
[Biological action mechanisms and effects of calcitriol].
Ugeskrift for laeger 1999;161(41):5669-74.
1999: M Kveiborg; Moustapha Kassem; Bente Langdahl; EF Eriksen; Brian F C Clark; Suresh Rattan
Telomere shortening during aging of human osteoblasts in vitro and leukocytes in vivo: lack of excessive telomere loss in osteoporotic patients.
Mechanisms of ageing and development 1999;106(3):261-71.
1998: Moustapha Kassem; Kim Brixen; Leif Mosekilde; Werner Blum; Allan Flyvbjerg
Effects of growth hormone treatment on serum levels of insulin-like growth factors (IGFs) and IGF binding proteins 1-4 in postmenopausal women.
Clinical endocrinology 1998;49(6):747-56.
1996: Erik Fink Eriksen; Moustapha Kassem; Bente Langdahl
European and North American Experience with HRT for the prevention of osteoporosis.
Bone 1996;19(5 Suppl):179S-183S.
1996: Erik Fink Eriksen; Moustapha Kassem; Bente Langdahl
Growth hormone, insulin-like growth factors and bone remodelling.
European journal of clinical investigation 1996;26(7):525-34.
1995: Kim Brixen; Moustapha Kassem; H K Nielsen; A G Loft; A Flyvbjerg; Leif Mosekilde
Short-term treatment with growth hormone stimulates osteoblastic and osteoclastic activity in osteopenic postmenopausal women: a dose response study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(12):1865-74.
1994: Moustapha Kassem; X Zhang; S Brask; Erik Fink Eriksen; Leif Mosekilde; T A Kruse
Familial isolated primary hyperparathyroidism.
Clinical endocrinology 1994;41(4):415-20.
1994: Moustapha Kassem; Kim Brixen; Werner Blum; Leif Mosekilde; Erik Fink Eriksen
Normal osteoclastic and osteoblastic responses to exogenous growth hormone in patients with postmenopausal spinal osteoporosis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(9):1365-70.
1994: Moustapha Kassem; Kim Brixen; W Blum; Leif Mosekilde; Erik Fink Eriksen
No evidence for reduced spontaneous or growth-hormone-stimulated serum levels of insulin-like growth factor (IGF)-I, IGF-II or IGF binding protein 3 in women with spinal osteoporosis.
European journal of endocrinology / European Federation of Endocrine Societies 1994;131(2):150-5.
1994: Moustapha Kassem; Kim Brixen; Leif Mosekilde; Erik Fink Eriksen
Human marrow stromal osteoblast-like cells do not show reduced responsiveness to in vitro stimulation with growth hormone in patients with postmenopausal osteoporosis.
Calcified tissue international 1994;54(1):1-6.
1993: Moustapha Kassem; Leif Mosekilde; Erik Fink Eriksen
1,25-dihydroxyvitamin D3 potentiates fluoride-stimulated collagen type I production in cultures of human bone marrow stromal osteoblast-like cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(12):1453-8.
1993: Jens Bollerslev; S C Marks; S Pockwinse; Moustapha Kassem; Kim Brixen; T Steiniche; Leif Mosekilde
Ultrastructural investigations of bone resorptive cells in two types of autosomal dominant osteopetrosis.
Bone 1993;14(6):865-9.
1993: Moustapha Kassem; Leif Mosekilde; Erik Fink Eriksen
Effects of triiodothyronine on DNA synthesis and differentiation markers of normal human osteoblast-like cells in vitro.
Biochemistry and molecular biology international 1993;30(4):779-88.
1993: H Brockstedt; Moustapha Kassem; Erik Fink Eriksen; Leif Mosekilde; F Melsen
Age- and sex-related changes in iliac cortical bone mass and remodeling.
Bone 1993;14(4):681-91.
1993: J Rungby; Moustapha Kassem; Erik Fink Eriksen; Gorm Danscher
The von Kossa reaction for calcium deposits: silver lactate staining increases sensitivity and reduces background.
The Histochemical journal 1993;25(6):446-51.
1993: Moustapha Kassem; W Blum; J Ristelli; Leif Mosekilde; Erik Fink Eriksen
Growth hormone stimulates proliferation and differentiation of normal human osteoblast-like cells in vitro.
Calcified tissue international 1993;52(3):222-6.
1993: Kim Brixen; Moustapha Kassem; Erik Fink Eriksen; H K Nielsen; A Flyvbjerg; Leif Mosekilde
Growth hormone (GH) and adult bone remodeling: the potential use of GH in treatment of osteoporosis.
The Journal of pediatric endocrinology 1993;6(1):65-71.
1993: Erik Fink Eriksen; Moustapha Kassem; Kim Brixen
Growth hormone and insulin-like growth factors as anabolic therapies for osteoporosis.
Hormone research 1993;40(1-3):95-8.
1992: Moustapha Kassem; J Rungby; Leif Mosekilde; Erik Fink Eriksen
Ultrastructure of human osteoblasts and associated matrix in culture.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1992;100(6):490-7.
1992: H K Nielsen; Kim Brixen; Moustapha Kassem; P Charles; L Mosekilde
Inhibition of the morning cortisol peak abolishes the expected morning decrease in serum osteocalcin in normal males: evidence of a controlling effect of serum cortisol on the circadian rhythm in serum osteocalcin.
The Journal of clinical endocrinology and metabolism 1992;74(6):1410-4.
1991: H K Nielsen; Kim Brixen; Moustapha Kassem; S E Christensen; Leif Mosekilde
Diurnal rhythm in serum osteocalcin: relation with sleep, growth hormone, and PTH(1-84).
Calcified tissue international 1991;49(6):373-7.
1991: H K Nielsen; Kim Brixen; Moustapha Kassem; Leif Mosekilde
Acute effect of 1,25-dihydroxyvitamin D3, prednisone, and 1,25-dihydroxyvitamin D3 plus prednisone on serum osteocalcin in normal individuals.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(5):435-41.
1991: Moustapha Kassem; Leila Risteli; Leif Mosekilde; F Melsen; Erik Fink Eriksen
Formation of osteoblast-like cells from human mononuclear bone marrow cultures.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1991;99(3):269-74.
1991: Moustapha Kassem; L Mosekilde; J Rungby; Leif Mosekilde; F Melsen; Erik Fink Eriksen
Formation of osteoclasts and osteoblast-like cells in long-term human bone marrow cultures.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1991;99(3):262-8.