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Michael Kassiou

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TOP 3
Herve Boutin; Gavin Brown; Christopher Cawthorne; James Galea; Andrew D Greenhalgh; Karl Herholz; Peter Julyan; Michael Kassiou; Renaud Maroy; Christian Prenant; Alison Smigova; Shane M Wilkinson; Samuel D Banister; Nancy J Rothwell
[18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats.
Marie-Anne Peyronneau; Wadad Saba; Michel Bottlaender; Annelaure Damont; Frédéric Dollé; Sébastien Goutal; Michael Kassiou; Héric Valette
Metabolism and quantification of [(18)F]DPA-714, a new TSPO positron emission tomography radioligand.
Andrew J Gilmore; Marika Heblinski; Michael Kassiou; Aaron Reynolds; Mark Connor
Inhibition of human recombinant T-type calcium channels by N-arachidonoyl 5-HT.

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2013: Herve Boutin; Gavin Brown; Christopher Cawthorne; James Galea; Andrew D Greenhalgh; Karl Herholz; Peter Julyan; Michael Kassiou; Renaud Maroy; Christian Prenant; Alison Smigova; Shane M Wilkinson; Samuel D Banister; Nancy J Rothwell
[18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats.
PloS one 2013;8(2):e56441.
2013: Marie-Anne Peyronneau; Wadad Saba; Michel Bottlaender; Annelaure Damont; Frédéric Dollé; Sébastien Goutal; Michael Kassiou; Héric Valette
Metabolism and quantification of [(18)F]DPA-714, a new TSPO positron emission tomography radioligand.
Drug metabolism and disposition: the biological fate of chemicals 2013;41(1):122-31.
2012: Andrew J Gilmore; Marika Heblinski; Michael Kassiou; Aaron Reynolds; Mark Connor
Inhibition of human recombinant T-type calcium channels by N-arachidonoyl 5-HT.
British journal of pharmacology 2012;167(5):1076-88.
2012: Samuel D Banister; Munikumar Reddy Doddareddy; David E Hibbs; Miral Manoli; Michael Kassiou
A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs).
Bioorganic & medicinal chemistry letters 2012;22(19):6053-8.
2012: Iman A Moussa; Robert H Mach; Miral Manoli; Samuel D Banister; Jinquan Cui; Munikumar Reddy Doddareddy; Michael Kassiou
Exploration of ring size in a series of cyclic vicinal diamines with σ₁ receptor affinity.
Bioorganic & medicinal chemistry letters 2012;22(17):5493-7.
2012: Joshua I Gosling; John M Haynes; Michael Kassiou; Colin W Pouton; Lyndon Warfe; Paul J White; Stephen P Baker; Peter J Scammells
Synthesis and biological evaluation of adenosines with heterobicyclic and polycyclic N(6)-substituents as adenosine A(1) receptor agonists.
ChemMedChem 2012;7(7):1191-201.
2012: Samuel D Banister; Louis M Rendina; Michael Kassiou
7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligands.
Bioorganic & medicinal chemistry letters 2012;22(12):4059-63.
2012: Nicolas Arlicot; Jean-Louis Baulieu; Philippe Corcia; Michael Kassiou; Serge Maia; Aaron Reynolds; Maria-João Ribeiro; Michael G Stabin; Clovis Tauber; Yann Venel; Johnny Vercouillie; Denis Guilloteau
Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation.
Nuclear medicine and biology 2012;39(4):570-8.
2012: Corinne Beinat; Mary Chebib; Munikumar Reddy Doddareddy; David Hibbs; Michael Sako; Thao Tran; Saundra van Prehn; Yingxian Xiao; Nour Al-Muhtasib; Samuel D Banister; Michael Kassiou
Consequences of linker length alteration of the α7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333.
Bioorganic & medicinal chemistry letters 2012;22(7):2380-4.
2012: Katherine R Leaver; Aaron Reynolds; Sylvie Bodard; Sylvie Chalon; Denis Guilloteau; Michael Kassiou
Effects of translocator protein (18 kDa) ligands on microglial activation and neuronal death in the quinolinic-acid-injected rat striatum.
ACS chemical neuroscience 2012;3(2):114-9.
2012: Christopher J Endres; Kenneth L Gage; Michael Kassiou; Jennifer M Coughlin; Crystal C Watkins; Martin G Pomper
Radiation dosimetry and biodistribution of the TSPO ligand 11C-DPA-713 in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(2):330-5.
2012: Samuel D Banister; Michael Kassiou
The therapeutic potential of sigma (σ) receptors for the treatment of central nervous system diseases: evaluation of the evidence.
Current pharmaceutical design 2012;18(7):884-901.
2011: Ellen L Crossley; Fatiah Issa; Michael Kassiou; Alana M Scarf; Louis M Rendina
Synthesis and cellular uptake of boron-rich pyrazolopyrimidines: exploitation of the translocator protein for the efficient delivery of boron into human glioma cells.
Chemical communications (Cambridge, England) 2011;47(44):12179-81.
2011: Iman A Moussa; Steven R Meikle; Samuel D Banister; Nicolas Giboureau; Michael Kassiou
Synthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N'-[4-(2-fluoroethoxy)benzyl]piperazine, a novel σ1 receptor PET imaging agent.
Bioorganic & medicinal chemistry letters 2011;21(22):6820-3.
2011: Iman A Moussa; Fady N Akladios; Samuel D Banister; Sook Wern Chua; Michael Kassiou
Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine σ₁ receptor ligands.
Bioorganic & medicinal chemistry letters 2011;21(19):5707-10.
2011: Samuel D Banister; Sook Wern Chua; Jinquan Cui; Robert H Mach; David T Yoo; Michael Kassiou
N-Arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (σ) receptor ligands.
Bioorganic & medicinal chemistry letters 2011;21(18):5289-92.
2011: Fatiah Issa; Michael Kassiou; Louis M Rendina
Boron in drug discovery: carboranes as unique pharmacophores in biologically active compounds.
Chemical reviews 2011;111(9):5701-22.
2011: A A Boucher; C Brown; G E Hunt; J C Arnold; Max R Bennett; I S McGregor; J Spencer; A Spiro; Michael Kassiou
Resilience and reduced c-Fos expression in P2X7 receptor knockout mice exposed to repeated forced swim test.
Neuroscience 2011;189():170-7.
2011: Annelaure Damont; Raphaël Boisgard; Eleonora Da Pozzo; Michael Kassiou; Bertrand Kuhnast; Frédéric Lemée; Claudia Martini; Guillaume Raggiri; Alana M Scarf; Silvia Selleri; Bertrand Tavitian; Frédéric Dollé
Synthesis of 6-[¹⁸F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET.
Bioorganic & medicinal chemistry letters 2011;21(16):4819-22.
2011: Caroline Drake; Sheila Francis; Rachel F Georgiou; Alexander Gerhard; Karl Herholz; Rainer Hinz; Stephen J Hopkins; Sharon Hulme; Matthew S Jones; Peter Julyan; Michael Kassiou; Renaud Maroy; Barry W McColl; Christian Prenant; Spencer D Proctor; Nancy J Rothwell; James C Russell; Johann R Selvarajah; Alison Smigova; Pippa J Tyrrell; Andy Vail; Herve Boutin; Gavin Brown; David Crossman; Adam Denes; Stuart M Allan
Brain inflammation is induced by co-morbidities and risk factors for stroke.
Brain, behavior, and immunity 2011;25(6):1113-22.
2011: Samuel D Banister; Iman A Moussa; William T Jorgensen; Sook Wern Chua; Michael Kassiou
Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivity.
Bioorganic & medicinal chemistry letters 2011;21(12):3622-6.
2011: Alana M Scarf; Michael Kassiou
The translocator protein.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(5):677-80.
2011: Abraham Martín; Raphaël Boisgard; Michael Kassiou; Frédéric Dollé; Bertrand Tavitian
Reduced PBR/TSPO expression after minocycline treatment in a rat model of focal cerebral ischemia: a PET study using [(18)F]DPA-714.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011;13(1):10-5.
2011: Samuel D Banister; Iman A Moussa; Corinne Beinat; Aaron J Reynolds; Paolo Schiavini; William T Jorgensen; Michael Kassiou
Trishomocubane as a scaffold for the development of selective dopamine transporter (DAT) ligands.
Bioorganic & medicinal chemistry letters 2011;21(1):38-41.
2010: Daniel E Morrison; Fatiah Issa; Mohan Bhadbhade; Ludwig Groebler; Paul K Witting; Michael Kassiou; Peter J Rutledge; Louis M Rendina
Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptake.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2010;15(8):1305-18.
2010: Aaron Reynolds; Raphy Hanani; David Hibbs; Annelaure Damont; Eleonora Da Pozzo; Silvia Selleri; Frédéric Dollé; Claudia Martini; Michael Kassiou
Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO).
Bioorganic & medicinal chemistry letters 2010;20(19):5799-802.
2010: Iman A Moussa; Samuel D Banister; Corinne Beinat; Nicolas Giboureau; Aaron J Reynolds; Michael Kassiou
Design, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands.
Journal of medicinal chemistry 2010;53(16):6228-39.
2010: Hendra Gunosewoyo; Michael Kassiou
P2X purinergic receptor ligands: recently patented compounds.
Expert opinion on therapeutic patents 2010;20(5):625-46.
2010: S Naidoo-Variawa; W Lehnert; Michael Kassiou; Richard B Banati; Steven Meikle
Attenuation correction for the large non-human primate brain imaging using microPET.
Physics in medicine and biology 2010;55(8):2351-63.
2010: Samuel D Banister; Jack K Clegg; Raphy Hanani; Michael Kassiou
11-{[2-(3-Fluoro-phen-yl)eth-yl](meth-yl)amino}-penta-cyclo-[5.4.0.0.0.0]undecan-8-one.
Acta crystallographica. Section E, Structure reports online 2010;66(Pt 10):o2693.
2010: C Beinat; S Banister; I Moussa; A J Reynolds; C S P McErlean; Michael Kassiou
Insights into structure-activity relationships and CNS therapeutic applications of NR2B selective antagonists.
Current medicinal chemistry 2010;17(34):4166-90.
2010: Nicolas Giboureau; Ian Mat Som; Aurélie Boucher-Arnold; Denis Guilloteau; Michael Kassiou
PET radioligands for the vesicular acetylcholine transporter (VAChT).
Current topics in medicinal chemistry 2010;10(15):1569-83.
2010: Samuel D Banister; Iman A Moussa; Meredith J T Jordan; Mark J Coster; Michael Kassiou
Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling.
Bioorganic & medicinal chemistry letters 2010;20(1):145-8.
2010: Abraham Martín; Raphaël Boisgard; Benoit Thézé; Nadja Van Camp; Bertrand Kuhnast; Annelaure Damont; Michael Kassiou; Frédéric Dollé; Bertrand Tavitian
Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(1):230-41.
2009: Amelia R Edington; Audra A McKinzie; Aaron J Reynolds; Michael Kassiou; Renae M Ryan; Robert J Vandenberg
Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport.
The Journal of biological chemistry 2009;284(52):36424-30.
2009: Katherine R Leaver; Haydn N Allbutt; Nathan J Creber; Michael Kassiou; Jasmine M Henderson
Oral pre-treatment with epigallocatechin gallate in 6-OHDA lesioned rats produces subtle symptomatic relief but not neuroprotection.
Brain research bulletin 2009;80(6):397-402.
2009: Janine Doorduin; Hans C Klein; Rudi A Dierckx; Michelle James; Michael Kassiou; Erik F J de Vries
[11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2009;11(6):386-98.
2009: Héric Valette; Yingxiang Xiao; Marie-Anne Peyronneau; Annelaure Damont; Alan P Kozikowski; Zhi-Liang Wei; Michael Kassiou; Kenneth J Kellar; Frédéric Dollé; Michel Bottlaender
18F-ZW-104: a new radioligand for imaging neuronal nicotinic acetylcholine receptors--in vitro binding properties and PET studies in baboons.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(8):1349-55.
2009: Christopher J Endres; Martin G Pomper; Michelle James; Ovsev Uzuner; Dima A Hammoud; Crystal C Watkins; Aaron Reynolds; John Hilton; Robert F Dannals; Michael Kassiou
Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(8):1276-82.
2009: Hendra Gunosewoyo; Mark J Coster; Maxwell R Bennett; Michael Kassiou
Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening.
Bioorganic & medicinal chemistry 2009;17(14):4861-5.
2009: Fabien Chauveau; Nadja Van Camp; Frédéric Dollé; Bertrand Kuhnast; Françoise Hinnen; Annelaure Damont; Hervé Boutin; Michelle James; Michael Kassiou; Bertrand Tavitian
Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(3):468-76.
2009: Linda Truong; Haydn N Allbutt; Mark J Coster; Michael Kassiou; Jasmine M Henderson
Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions.
Brain research bulletin 2009;78(2-3):91-6.
2009: Jasmine M Henderson; Jose Lanciego; Yoland Smith; Andrew Gundlach; Michael Kassiou
Proceedings of the 2007 international brain research organisation satellite meeting "movement disorders: focus on the thalamus and basal ganglia" held in Sydney, Australia, 10-11 July 2007.
Brain research bulletin 2009;78(2-3):53-4.
2009: S T Warraich; Haydn N Allbutt; R Billing; J Radford; Mark J Coster; Michael Kassiou; Jasmine M Henderson
Evaluation of behavioural effects of a selective NMDA NR1A/2B receptor antagonist in the unilateral 6-OHDA lesion rat model.
Brain research bulletin 2009;78(2-3):85-90.
2009: Michael Kassiou; Richard B Banati; R. M. Damian Holsinger; Steve Meikle
Challenges in molecular imaging of Parkinson's disease: a brief overview.
Brain research bulletin 2009;78(2-3):105-8.
2009: Alana M Scarf; Lars M Ittner; Michael Kassiou
The translocator protein (18 kDa): central nervous system disease and drug design.
Journal of medicinal chemistry 2009;52(3):581-92.
2009: Frédéric Dollé; Christopher Luus; Aaron Reynolds; Michael Kassiou
Radiolabelled molecules for imaging the translocator protein (18 kDa) using positron emission tomography.
Current medicinal chemistry 2009;16(22):2899-923.
2008: K R Leaver; Haydn N Allbutt; N J Creber; Michael Kassiou; Jasmine M Henderson
Neuroprotective effects of a selective N-methyl-D-aspartate NR2B receptor antagonist in the 6-hydroxydopamine rat model of Parkinson's disease.
Clinical and experimental pharmacology & physiology 2008;35(11):1388-94.
2008: Hendra Gunosewoyo; Jun Liu Guo; Maxwell R Bennett; Mark J Coster; Michael Kassiou
Cubyl amides: novel P2X7 receptor antagonists.
Bioorganic & medicinal chemistry letters 2008;18(13):3720-3.
2008: Laurent Besret; Frédéric Dollé; Anne-Sophie Hérard; Martine Guillermier; Stéphane Demphel; Françoise Hinnen; Christine Coulon; Michèle Ottaviani; Michel Bottlaender; Philippe Hantraye; Michael Kassiou
Dopamine D1 receptor imaging in the rodent and primate brain using the isoquinoline +-[11C]A-69024 and positron emission tomography.
Journal of pharmaceutical sciences 2008;97(7):2811-9.
2008: Addy van Dijk; Christopher Johnston; Haydn N Allbutt; Michael Kassiou; Jasmine Henderson
Behavioural effects of trishomocubanes in rats with unilateral 6-hydroxydopamine lesions.
Behavioural brain research 2008;190(1):14-21.
2008: Michelle L James; Roger R Fulton; Johnny Vercoullie; David J Henderson; Lucette Garreau; Sylvie Chalon; Frederic Dolle; Barbara Costa; Silvia Selleri; Denis Guilloteau; Michael Kassiou
DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(5):814-22.
2007: Nicolas Giboureau; Patrick Emond; Roger R Fulton; David J Henderson; Sylvie Chalon; Lucette Garreau; Peter Roselt; Stefan Eberl; Sylvie Mavel; Sylvie Bodard; Michael J Fulham; Denis Guilloteau; Michael Kassiou
Ex vivo and in vivo evaluation of (2R,3R)-5-[(18)F]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter.
Synapse (New York, N.Y.) 2007;61(12):962-70.
2007: S Naidoo-Variawa; A J Hey-Cunningham; W Lehnert; Peter L Kench; Michael Kassiou; Richard B Banati; Steven Meikle
High-resolution imaging of the large non-human primate brain using microPET: a feasibility study.
Physics in medicine and biology 2007;52(22):6627-38.
2007: Patrick Emond; Sylvie Mavel; Yolanda Zea-Ponce; Michael Kassiou; Lucette Garreau; Sylvie Bodard; Marie-Laure Drossard; Sylvie Chalon; Denis Guilloteau
(E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter.
Nuclear medicine and biology 2007;34(8):967-71.
2007: Annachiara Cagnin; Michael Kassiou; Steven Meikle; Richard B Banati
Positron emission tomography imaging of neuroinflammation.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2007;4(3):443-52.
2007: Hervé Boutin; Fabien Chauveau; Cyrille Thominiaux; Marie-Claude Grégoire; Michelle L James; Régine Trebossen; Philippe Hantraye; Frédéric Dollé; Bertrand Tavitian; Michael Kassiou
11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(4):573-81.
2007: Mitchell Quinlivan; Sylvie Chalon; Jackie Vergote; Jasmine Henderson; Andrew Katsifis; Michael Kassiou; Denis Guilloteau
Decreased vesicular acetylcholine transporter and alpha(4)beta(2) nicotinic receptor density in the rat brain following 192 IgG-saporin immunolesioning.
Neuroscience letters 2007;415(2):97-101.
2007: Xiang Liu; Samuel D Banister; MacDonald J Christie; Richard B Banati; Steven Meikle; Mark J Coster; Michael Kassiou
Trishomocubanes: novel sigma ligands modulate cocaine-induced behavioural effects.
European journal of pharmacology 2007;555(1):37-42.
2007: Hendra Gunosewoyo; Mark J Coster; Michael Kassiou
Molecular probes for P2X7 receptor studies.
Current medicinal chemistry 2007;14(14):1505-23.
2007: T Lee Collier; Rikki N Waterhouse; Michael Kassiou
Imaging sigma receptors: applications in drug development.
Current pharmaceutical design 2007;13(1):51-72.
2007: Alan P Kozikowski; Sheela K Chellappan; David Henderson; Roger Fulton; Nicolas Giboureau; Yingxian Xiao; Zhi-Liang Wei; Denis Guilloteau; Patrick Emond; Frederic Dolle; Kenneth J Kellar; Michael Kassiou
Acetylenic pyridines for use in PET imaging of nicotinic receptors.
ChemMedChem 2007;2(1):54-7.
2006: Thaer Assaad; Sylvie Mavel; Stanley M Parsons; Shane Kruse; Laurent Galineau; Hassan Allouchi; Michael Kassiou; Sylvie Chalon; Denis Guilloteau; Patrick Emond
Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands.
Bioorganic & medicinal chemistry letters 2006;16(10):2654-7.
2006: Cyrille Thominiaux; Frédéric Dollé; Michelle L James; Yann Bramoullé; Hervé Boutin; Laurent Besret; Marie-Claude Grégoire; Héric Valette; Michel Bottlaender; Bertrand Tavitian; Philippe Hantraye; S Selleri; Michael Kassiou
Improved synthesis of the peripheral benzodiazepine receptor ligand [11C]DPA-713 using [11C]methyl triflate.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2006;64(5):570-3.
2006: Linda Truong; Haydn N Allbutt; Michael Kassiou; Jasmine M Henderson
Developing a preclinical model of Parkinson's disease: a study of behaviour in rats with graded 6-OHDA lesions.
Behavioural brain research 2006;169(1):1-9.
2006: Johnny Vercouillie; Sylvie Mavel; Laurent Galineau; Tiziana Ragusa; Robert Innis; Michael Kassiou; Sylvie Chalon; Frédéric Dollé; Jean-Claude Besnard; Denis Guilloteau; Patrick Emond
Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands.
Bioorganic & medicinal chemistry letters 2006;16(5):1297-300.
2006: Cyrille Thominiaux; Béatrice de Bruin; Yann Bramoullé; Françoise Hinnen; Stéphane Demphel; Héric Valette; Michel Bottlaender; Laurent Besret; Michael Kassiou; Frédéric Dollé
Radiosynthesis of (E)-N-(2-[11C]methoxybenzyl)-3-phenyl-acrylamidine, a novel subnanomolar NR2B subtype-selective NMDA receptor antagonist.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2006;64(3):348-54.
2006: Annachiara Cagnin; Michael Kassiou; Steven Meikle; Richard B Banati
In vivo evidence for microglial activation in neurodegenerative dementia.
Acta neurologica Scandinavica. Supplementum 2006;185():107-14.
2006: Michelle L James; Silvia Selleri; Michael Kassiou
Development of ligands for the peripheral benzodiazepine receptor.
Current medicinal chemistry 2006;13(17):1991-2001.
2005: Steven Meikle; Peter L Kench; Michael Kassiou; Richard B Banati
Small animal SPECT and its place in the matrix of molecular imaging technologies.
Physics in medicine and biology 2005;50(22):R45-61.
2005: Michelle L James; Roger R Fulton; David J Henderson; Stefan Eberl; Steven Meikle; Sally Thomson; Robin D Allan; Frederic Dolle; Michael J Fulham; Michael Kassiou
Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand.
Bioorganic & medicinal chemistry 2005;13(22):6188-94.
2005: Michael Kassiou; Robert F Dannals; Xiang Liu; Dean F Wong; Hayden T Ravert; Ursula Scheffel
Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors.
Bioorganic & medicinal chemistry 2005;13(11):3623-6.
2005: Michael Kassiou; Steven Meikle; Richard B Banati
Ligands for peripheral benzodiazepine binding sites in glial cells.
Brain research. Brain research reviews 2005;48(2):207-10.
2005: Yolanda Zea-Ponce; Sylvie Mavel; Thaer Assaad; Shane E Kruse; Stanley M Parsons; Patrick Emond; Sylvie Chalon; Nicolas Giboureau; Michael Kassiou; Denis Guilloteau
Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter.
Bioorganic & medicinal chemistry 2005;13(3):745-53.
2005: Armin Mohamed; Stefan Eberl; Michael J Fulham; Michael Kassiou; Aysha Zaman; David Henderson; Scott Beveridge; Chris J Constable; Sing Kai Lo
Sequential 123I-iododexetimide scans in temporal lobe epilepsy: comparison with neuroimaging scans (MR imaging and 18F-FDG PET imaging).
European journal of nuclear medicine and molecular imaging 2005;32(2):180-5.
2005: Xiang Liu; Filomena Mattner; Andrew Katsifis; MacDonald Christie; Michael Kassiou
Influence of trishomocubanes on sigma receptor binding of N-(1-benzyl-piperidin-4-yl)-4-[123I]iodobenzamide in vivo in the rat brain.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2005;1(1):31-8.
2004: Andrew Katsifis; Michael Kassiou
Development of radioligands for in vivo imaging of GABA(A)-benzodiazepine receptors.
Mini reviews in medicinal chemistry 2004;4(8):909-21.
2004: Gaëlle Roger; Frédéric Dollé; Béatrice de Bruin; X Liu; Laurent Besret; Yann Bramoullé; Christine Coulon; Michèle Ottaviani; Michel Bottlaender; Héric Valette; Michael Kassiou
Radiosynthesis and pharmacological evaluation of [11C]EMD-95885: a high affinity ligand for NR2B-containing NMDA receptors.
Bioorganic & medicinal chemistry 2004;12(12):3229-37.
2004: David J Henderson; Stefan Eberl; Sally Thomson; A Smith; Robin D Allan; Michael J Fulham; R Loiacono; Michael Kassiou
3-Pyridyl ethers as SPECT radioligands for imaging nicotinic acetylcholine receptors.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2004;60(5):669-76.
2004: Peter Roselt; Steven Meikle; Michael Kassiou
The role of positron emission tomography in the discovery and development of new drugs; as studied in laboratory animals.
European journal of drug metabolism and pharmacokinetics 2004;29(1):1-6.
2003: Gaëlle Roger; Béatrice Lagnel; Laurent Besret; Yann Bramoullé; Christine Coulon; Michèle Ottaviani; Michael Kassiou; Michel Bottlaender; Héric Valette; Frédéric Dollé
Synthesis, radiosynthesis and in vivo evaluation of 5-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]-1,3-dihydrobenzoimidazol-2-[(11)C]one, as a potent NR(1A)/2B subtype selective NMDA PET radiotracer.
Bioorganic & medicinal chemistry 2003;11(24):5401-8.
2003: Mitchell Quinlivan; Filomena Mattner; Vahan Papazian; Jia Zhou; Andrew Katsifis; Patrick Emond; Sylvie Chalon; Alan P Kozikowski; Denis Guilloteau; Michael Kassiou
Synthesis and evaluation of iodine-123 labelled tricyclic tropanes as radioligands for the serotonin transporter.
Nuclear medicine and biology 2003;30(7):741-6.
2003: Andrew Katsifis; Karine Mardon; Filomena Mattner; Christian Loc'h; Meredith E McPhee; Branko Dikic; Michael Kassiou; Damon D Ridley
Pharmacological evaluation of (S)-8-[123I]iodobretazenil: a radioligand for in vivo studies of central benzodiazepine receptors.
Nuclear medicine and biology 2003;30(2):191-8.
2002: Michael Kassiou; Christian Loc'h; Frederic Dolle; John L Musachio; L Dolci; Christian Crouzel; Robert F Dannals; B Mazière
Preparation of a bromine-76 labelled analogue of epibatidine: a potent ligand for nicotinic acetylcholine receptor studies.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2002;57(5):713-7.
2002: Michael Kassiou; Michel Bottlaender; Christian Loc'h; Frederic Dolle; John L Musachio; Christine Coulon; Michèle Ottaviani; Robert F Dannals; Bernard Maziere
Pharmacological evaluation of a Br-76 analog of epibatidine: a potent ligand for studying brain nicotinic acetylcholine receptors.
Synapse (New York, N.Y.) 2002;45(2):95-104.
2002: Michael Kassiou; Christian Loc'h; Michel Bottlaender; Karine Mardon; Michèle Ottaviani; Christine Coulon; Andrew Katsifis; Bernard Maziere
(+)-[76Br]A-69024: a non-benzazepine radioligand for studies of dopamine D1 receptors using PET.
Nuclear medicine and biology 2002;29(3):295-302.
2001: Michael Kassiou; Karine Mardon; Filomena Mattner; Andrew Katsifis; Branko Dikic
Pharmacological evaluation of (+)-2- [123I]A-69024: a radioligand for in vivo studies of dopamine D1 receptors.
Life sciences 2001;69(6):669-75.
2001: Xiang Liu; Samer J Nuwayhid; MacDonald J Christie; Michael Kassiou; L L Werling
Trishomocubanes: novel sigma-receptor ligands modulate amphetamine-stimulated [3H]dopamine release.
European journal of pharmacology 2001;422(1-3):39-45.
2001: Michael Kassiou; Stefan Eberl; Steven Meikle; Alex M Birrell; Chris J Constable; Michael J Fulham; Dean F Wong; John L Musachio
In vivo imaging of nicotinic receptor upregulation following chronic (-)-nicotine treatment in baboon using SPECT.
Nuclear medicine and biology 2001;28(2):165-75.
2000: Steven Meikle; Stefan Eberl; Roger R Fulton; Michael Kassiou; Michael J Fulham
The influence of tomograph sensitivity on kinetic parameter estimation in positron emission tomography imaging studies of the rat brain.
Nuclear medicine and biology 2000;27(6):617-25.
1999: Karine Mardon; Michael Kassiou; A Donald
Effects of streptozotocin-induced diabetes on neuronal sigma receptors in the rat brain.
Life sciences 1999;65(23):PL 281-6.
1999: Karine Mardon; Michael Kassiou; Andrew Katsifis; L Najdovski
A study of myocardial muscarinic receptors in streptozotocin-induced diabetic rats using iodine-123 N-methyl-4-iododexetimide.
European journal of nuclear medicine 1999;26(7):743-9.
1999: V H Nguyen; Karine Mardon; Michael Kassiou; M D Christie
In vitro and in vivo characterisation of [3H]ANSTO-14 binding to the sigma 1 binding sites.
Nuclear medicine and biology 1999;26(2):209-15.
1998: V H Nguyen; Susan L Ingram; Michael Kassiou; MacDonald J Christie
Sigma-binding site ligands inhibit K+ currents in rat locus coeruleus neurons in vitro.
European journal of pharmacology 1998;361(1):157-63.
1998: Michael Kassiou; Ursula Scheffel; Hayden T Ravert; William B Mathews; John L Musachio; Edythe D London; Robert F Dannals
Pharmacological evaluation of [11C]A-84543: an enantioselective ligand for in vivo studies of neuronal nicotinic acetylcholine receptors.
Life sciences 1998;63(1):PL13-8.
1996: K L Boundy; Christopher C Rowe; A B Black; M I Kitchener; L R Barnden; R Sebben; A Kneebone; Michael Kassiou; Andrew Katsifis; R Lambrecht
Localization of temporal lobe epileptic foci with iodine-123 iododexetimide cholinergic neuroreceptor single-photon emission computed tomography.
Neurology 1996;47(4):1015-20.
1996: V H Nguyen; Michael Kassiou; Graham A R Johnston; MacDonald J Christie
Comparison of binding parameters of sigma 1 and sigma 2 binding sites in rat and guinea pig brain membranes: novel subtype-selective trishomocubanes.
European journal of pharmacology 1996;311(2-3):233-40.
1996: Christian Loc'h; Michael Kassiou; V Strijckmans; Michel Bottlaender; Andrew Katsifis; L Schmid; M Mazière; R M Lambrecht; B Mazière
Pharmacological characterization and positron emission tomography evaluation of 4-[76Br]bromodexetimide and 4-[76Br]bromolevetimide for investigations of central muscarinic cholinergic receptors.
Nuclear medicine and biology 1996;23(3):235-43.
1996: Michael Kassiou; Karine Mardon; Andrew Katsifis; L Najdovski; B Dikic; F Mattner; R M Lambrecht; R J Hicks; P Eu; Christian Loc'h
Radiosynthesis of [123I]N-methyl-4-iododexetimide and [123I]N-methyl-4-iodolevetimide: in vitro and in vivo characterisation of binding to muscarinic receptors in the rat heart.
Nuclear medicine and biology 1996;23(2):147-53.
1996: V Strijckmans; Christine Coulon; Michael Kassiou; Christian Loc'h; B Mazière
In vitro pharmacological properties of 4-bromodexetimide for muscarinic receptors.
Life sciences 1996;58(23):PL337-44.
1995: K L Boundy; L R Barnden; Christopher C Rowe; M Reid; Michael Kassiou; Andrew Katsifis; R M Lambrecht
Human dosimetry and biodistribution of iodine-123-iododexetimide: a SPECT imaging agent for cholinergic muscarinic neuroreceptors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1332-8.
1995: R J Hicks; Michael Kassiou; P Eu; Andrew Katsifis; M Garra; J Power; L Najdovski; R M Lambrecht
Iodine-123 N-methyl-4-iododexetimide: a new radioligand for single-photon emission tomographic imaging of myocardial muscarinic receptors.
European journal of nuclear medicine 1995;22(4):339-45.
1995: Michael Kassiou; Ursula Scheffel; Hayden T Ravert; William B Mathews; John L Musachio; R M Lambrecht; Robert F Dannals
[11C]A-69024: a potent and selective non-benzazepine radiotracer for in vivo studies of dopamine D1 receptors.
Nuclear medicine and biology 1995;22(2):221-6.
1995: Michael Kassiou; Ursula Scheffel; John L Musachio; M Stathis; Robert F Dannals
[3H]A-69024: a non-benzazepine ligand for in vitro and in vivo studies of dopamine D1 receptors.
Life sciences 1995;57(23):PL367-72.