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Jette Kastrup

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Monica Fiorentini; Jette S Kastrup; Kristian Strømgaard; Anders Bach; Michael Gajhede
Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy.
Lina Juknaitė; Jette S Kastrup; Andrew Eng; Karla Frydenvang; Yuichi Ishikawa; Darryl S Pickering; Ryuichi Sakai; Yutaro Sugamata; Geoffrey T Swanson; Satoshi Takamizawa; Kazuya Tokiwa; Masato Oikawa
Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization.
Christine A Ussing; Philip K Ahring; Bente Frølund; Michael Gajhede; Camilla P Hansen; Anders A Jensen; Jette S Kastrup; Elsebet Ø Nielsen; Jette G Petersen; Line A H Rohde; Thomas Balle
Synthesis, pharmacology, and biostructural characterization of novel α4β2 nicotinic acetylcholine receptor agonists.

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2013: Monica Fiorentini; Jette S Kastrup; Kristian Strømgaard; Anders Bach; Michael Gajhede
Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy.
Acta crystallographica. Section D, Biological crystallography 2013;69(Pt 4):587-94.
2013: Lina Juknaitė; Jette S Kastrup; Andrew Eng; Karla Frydenvang; Yuichi Ishikawa; Darryl S Pickering; Ryuichi Sakai; Yutaro Sugamata; Geoffrey T Swanson; Satoshi Takamizawa; Kazuya Tokiwa; Masato Oikawa
Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization.
Journal of medicinal chemistry 2013;56(6):2283-93.
2013: Christine A Ussing; Philip K Ahring; Bente Frølund; Michael Gajhede; Camilla P Hansen; Anders A Jensen; Jette S Kastrup; Elsebet Ø Nielsen; Jette G Petersen; Line A H Rohde; Thomas Balle
Synthesis, pharmacology, and biostructural characterization of novel α4β2 nicotinic acetylcholine receptor agonists.
Journal of medicinal chemistry 2013;56(3):940-51.
2013: Kasper Harpsøe; Marianne L Jensen; Jette S Kastrup; Elsebet Ø Nielsen; Dan Peters; Daniel B Timmermann; Thomas Balle; Tino Dyhring; Michael Gajhede; Helle Hald; Philip K Ahring
Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors.
The Journal of biological chemistry 2013;288(4):2559-70.
2012: Lina Juknaitė; Jette S Kastrup; Birgitte Nielsen; David J Aitken; Zeinab Assaf; Lennart Bunch; Sophie Faure; Karla Frydenvang; Michael Gajhede; Thierry Gefflaut; Raminta Venskutonytė; Darryl S Pickering
Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors.
Journal of structural biology 2012;180(1):39-46.
2012: Raminta Venskutonytė; Ewa Szymańska; Elena Antón Valadés; Karla Frydenvang; Tommy N Johansen; Jette S Kastrup; Darryl S Pickering
Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors.
ChemMedChem 2012;7(10):1793-8.
2012: Raminta Venskutonytė; Anna Ceravalls de Rabassa; Philip K Ahring; Karla Frydenvang; Michael Gajhede; Helle Hald; Jette S Kastrup
Kainate induces various domain closures in AMPA and kainate receptors.
Neurochemistry international 2012;61(4):536-45.
2012: Line H Kristensen; Michael Lees; Anders L Nielsen; Lars Olsen; Paul Cloos; Charlotte Helgstrand; Kristian Helin; Jette S Kastrup; Michael Gajhede
Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.
The FEBS journal 2012;279(11):1905-14.
2012: Anders Bach; Celestine N Chi; Bettina H Clausen; Michael Gajhede; Per Jemth; Jette S Kastrup; Anders Skov Kristensen; Kate Lykke Lambertsen; Patrik Lundström; Magda Møller; Klaus B Nissen; Adam Round; Pernille L Sørensen; Bente Vestergaard; Kristian Strømgaard
A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(9):3317-22.
2012: Line Aagot Hede Rohde; Philip K Ahring; Michael Gajhede; Kasper Harpsøe; Charlotte Helgstrand; Marianne L Jensen; Jette S Kastrup; Christian Krintel; Elsebet Ø Nielsen; Dan Peters; Thomas Balle
Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors: unique role of halogen bonding revealed.
The Journal of biological chemistry 2012;287(6):4248-59.
2012: Azadeh Shahsavar; Michael Gajhede; Jette S Kastrup; Jesper L Kristensen; Elsebet Ø Nielsen; Thomas Balle
Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHβE suggests a unique mode of antagonism.
PloS one 2012;7(8):e40757.
2011: Raminta Venskutonytė; Darryl S Pickering; Lennart Bunch; Karla Frydenvang; Michael Gajhede; Jette S Kastrup
Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate.
Journal of structural biology 2011;176(3):307-14.
2011: Ewa Szymańska; Alberto Contreras-Sanz; Elena Frola; Karla Frydenvang; Jette S Kastrup; Birgitte Nielsen; Darryl S Pickering; Zorica Serafimoska; Tommy N Johansen
A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: synthesis, resolution, pharmacology, and crystal structure.
Journal of medicinal chemistry 2011;54(20):7289-98.
2011: Raminta Venskutonyte; Elena Antón Valadés; Salvatore Valenti; Ahmad Amir; Margherita Brindisi; Stefania Butini; Giuseppe Campiani; Salvatore Sanna Coccone; Karla Frydenvang; Sandra Gemma; Egeria Guarino; Jette S Kastrup; Vinod Kumar; Samuele Maramai; Ettore Novellino; Darryl S Pickering
Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization.
Journal of medicinal chemistry 2011;54(13):4793-805.
2011: Jan B L Kristensen; Jesper L Kristensen; Line H Kristensen; Anders L Nielsen; Lars Olsen; Charlotte Helgstrand; Lars Jørgensen; Lina Juknaite; Jette S Kastrup; Rasmus P Clausen; Michael Gajhede
Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: towards understanding selectivity of inhibitors targeting oncogenic histone demethylases.
FEBS letters 2011;585(12):1951-6.
2011: Nikolaj Kulahin; Ole Kristensen; Kim K Rasmussen; Lars Olsen; Patrik Rydberg; Bente Vestergaard; Jette S Kastrup; Vladimir Berezin; Elisabeth Bock; Peter S Walmod; Michael Gajhede
Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule.
Structure (London, England : 1993) 2011;19(2):203-11.
2010: Xiaole Wang; Helle Hald; Heidi A Ernst; Jan Egebjerg; Kenneth Vielsted Christensen; Michael Gajhede; Jette S Kastrup; Osman Mirza
Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus.
Protein expression and purification 2010;71(2):179-83.
2009: Monica Fiorentini; Ann Kallehauge Nielsen; Ole Kristensen; Jette S Kastrup; Michael Gajhede
Structure of the first PDZ domain of human PSD-93.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 12):1254-7.
2009: Elise Champion; Magali Remaud-Simeon; Lars K Skov; Jette S Kastrup; Michael Gajhede; Osman Mirza
The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 12):1309-14.
2009: Heidi A Ernst; Antony Pham; Helle Hald; Jette S Kastrup; Moazur Rahman; Osman Mirza
Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides.
Biochemical and biophysical research communications 2009;389(1):112-6.
2009: Helle Hald; Philip K Ahring; Daniel B Timmermann; Tommy Liljefors; Michael Gajhede; Jette S Kastrup
Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.
Journal of molecular biology 2009;391(5):906-17.
2009: Rasmus P Clausen; Peter Naur; Anders Skov Kristensen; Jeremy R Greenwood; Mette Strange; Hans Bräuner-Osborne; Anders A Jensen; Anne Sophie T Nielsen; Ulla Geneser; Lone M Ringgaard; Birgitte Nielsen; Darryl S Pickering; Lotte Brehm; Michael Gajhede; Povl Krogsgaard-Larsen; Jette S Kastrup
The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization.
Journal of medicinal chemistry 2009;52(15):4911-22.
2009: Karla Frydenvang; L Leanne Lash; Peter Naur; Pekka A Postila; Darryl S Pickering; Caleb M Smith; Michael Gajhede; Makoto Sasaki; Ryuichi Sakai; Olli T Pentikaïnen; Geoffrey T Swanson; Jette S Kastrup
Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.
The Journal of biological chemistry 2009;284(21):14219-29.
2009: Kasper B Hansen; Peter Naur; Natalie L Kurtkaya; Anders Skov Kristensen; Michael Gajhede; Jette S Kastrup; Stephen F Traynelis
Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(4):907-17.
2008: Christina Kasper; Karla Frydenvang; Peter Naur; Michael Gajhede; Darryl S Pickering; Jette S Kastrup
Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4.
FEBS letters 2008;582(29):4089-94.
2008: Kim K Rasmussen; Nikolaj Kulahin; Ole Kristensen; Jens-Christian Navarro Poulsen; Bent W Sigurskjold; Jette S Kastrup; Vladimir Berezin; Elisabeth Bock; Peter S Walmod; Michael Gajhede
Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping.
Journal of molecular biology 2008;382(5):1113-20.
2008: Gabriel Paës; Lars K Skov; Michael O'Donohue; Caroline Rémond; Jette S Kastrup; Michael Gajhede; Osman Mirza
The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit.
Biochemistry 2008;47(28):7441-51.
2008: Gustav Røder; Ole Kristensen; Jette S Kastrup; Soren Buus; Michael Gajhede
Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 6):459-62.
2008: Nikolaj Kulahin; Vladislav V Kiselyov; Artur Kochoyan; Ole Kristensen; Jette S Kastrup; Vladimir Berezin; Elisabeth Bock; Michael Gajhede
Dimerization effect of sucrose octasulfate on rat FGF1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 6):448-52.
2008: Anders Dysted Jørgensen; Jane Nøhr; Jette S Kastrup; Michael Gajhede; Bent W Sigurskjold; Jørgen Sauer; Dmitri I Svergun; Birte Svensson; Bente Vestergaard
Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution.
The Journal of biological chemistry 2008;283(21):14772-80.
2008: Mads Beich-Frandsen; Darryl S Pickering; Osman Mirza; Tommy N Johansen; Jeremy Greenwood; Bente Vestergaard; Arne Schousboe; Michael Gajhede; Tommy Liljefors; Jette S Kastrup
Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency.
Journal of medicinal chemistry 2008;51(5):1459-63.
2007: Birgitte H Kaae; Kasper Harpsøe; Jette S Kastrup; Alberto Contreras Sanz; Darryl S Pickering; Bjørn Metzler; Rasmus P Clausen; Michael Gajhede; Per Sauerberg; Tommy Liljefors; Ulf Madsen
Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites.
Chemistry & biology 2007;14(11):1294-303.
2007: Helle Hald; Peter Naur; Darryl S Pickering; Desiree Sprogøe; Ulf Madsen; Daniel B Timmermann; Philip K Ahring; Tommy Liljefors; Arne Schousboe; Jan Egebjerg; Michael Gajhede; Jette S Kastrup
Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
The Journal of biological chemistry 2007;282(35):25726-36.
2007: Peter Naur; Kasper B Hansen; Anders Skov Kristensen; Shashank M Dravid; Darryl S Pickering; Lars Olsen; Bente Vestergaard; Jan Egebjerg; Michael Gajhede; Stephen F Traynelis; Jette S Kastrup
Ionotropic glutamate-like receptor delta2 binds D-serine and glycine.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):14116-21.
2007: Stine B Vogensen; Karla Frydenvang; Jeremy R Greenwood; Giovanna Postorino; Birgitte Nielsen; Darryl S Pickering; Bjarke Ebert; Ulrik Bølcho; Jan Egebjerg; Michael Gajhede; Jette S Kastrup; Tommy N Johansen; Rasmus P Clausen; Povl Krogsgaard-Larsen
A tetrazolyl-substituted subtype-selective AMPA receptor agonist.
Journal of medicinal chemistry 2007;50(10):2408-14.
2007: Bente Vestergaard; Minna Groenning; Manfred Roessle; Jette S Kastrup; Marco van de Weert; James M Flink; Sven Frokjaer; Michael Gajhede; Dmitri I Svergun
A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils.
PLoS biology 2007;5(5):e134.
2007: Birthe Ross; Ole Kristensen; Dimitri Favre; Joël Walicki; Jette S Kastrup; Christian Widmann; Michael Gajhede
High resolution crystal structures of the p120 RasGAP SH3 domain.
Biochemical and biophysical research communications 2007;353(2):463-8.
2007: Nikolaj Kulahin; Vladislav V Kiselyov; Artur Kochoyan; Ole Kristensen; Jette S Kastrup; Vladimir Berezin; Elisabeth Bock; Michael Gajhede
Structure of rat acidic fibroblast growth factor at 1.4 A resolution.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 2):65-8.
2006: Thomas Blicher; Jette S Kastrup; Lars Østergaard Pedersen; Soren Buus; Michael Gajhede
Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 12):1179-84.
2006: Osman Mirza; Lars K Skov; Desiree Sprogøe; Lambertus van den Broek; Gerrit Beldman; Jette S Kastrup; Michael Gajhede
Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion.
The Journal of biological chemistry 2006;281(46):35576-84.
2006: Lars K Skov; Ulla Seppälä; Jeremy J F Coen; Neil Crickmore; Te Piao King; Rafael Monsalve; Jette S Kastrup; Michael D Spangfort; Michael Gajhede
Structure of recombinant Ves v 2 at 2.0 Angstrom resolution: structural analysis of an allergenic hyaluronidase from wasp venom.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 6):595-604.
2006: Christina Kasper; Darryl S Pickering; Osman Mirza; Lars Olsen; Anders Skov Kristensen; Jeremy R Greenwood; Tommy Liljefors; Arne Schousboe; Frank Wätjen; Michael Gajhede; Bent W Sigurskjold; Jette S Kastrup
The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209.
Journal of molecular biology 2006;357(4):1184-201.
2006: Ole Kristensen; Sylvie Guenat; Imran Dar; Nathalie Allaman-Pillet; Amar Abderrahmani; Mourad Ferdaoussi; Raphael Roduit; Fabienne Maurer; Jacques Beckmann; Jette S Kastrup; Michael Gajhede; Christophe Bonny
A unique set of SH3-SH3 interactions controls IB1 homodimerization.
The EMBO journal 2006;25(4):785-97.
2005: Bente Vestergaard; Suparna Sanyal; Manfred Roessle; Liliana Mora; Richard H Buckingham; Jette S Kastrup; Michael Gajhede; Dmitri I Svergun; Måns Ehrenberg
The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure.
Molecular cell 2005;20(6):929-38.
2005: Mai Marie Holm; Peter Naur; Bente Vestergaard; Matthew T Geballe; Michael Gajhede; Jette S Kastrup; Stephen F Traynelis; Jan Egebjerg
A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.
The Journal of biological chemistry 2005;280(42):35469-76.
2005: Nikolaj Kulahin; Christina Kasper; Ole Kristensen; Jette S Kastrup; Vladimir Berezin; Elisabeth Bock; Michael Gajhede
Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 9):858-60.
2005: Mai Marie Holm; Marie-Louise Lunn; Stephen F Traynelis; Jette S Kastrup; Jan Egebjerg
Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(34):12053-8.
2005: Thomas Blicher; Jette S Kastrup; Soren Buus; Michael Gajhede
High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 8):1031-40.
2005: Bettina Bryde Nielsen; Darryl S Pickering; Jeremy R Greenwood; Lotte Brehm; Michael Gajhede; Arne Schousboe; Jette S Kastrup
Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP.
The FEBS journal 2005;272(7):1639-48.
2005: Anne Frandsen; Darryl S Pickering; Bente Vestergaard; Christina Kasper; Bettina Bryde Nielsen; Jeremy R Greenwood; Giuseppe Campiani; Caterina Fattorusso; Michael Gajhede; Arne Schousboe; Jette S Kastrup
Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2.
Molecular pharmacology 2005;67(3):703-13.
2005: Birthe R Johannessen; Lars K Skov; Jette S Kastrup; Ole Kristensen; Caroline Bolwig; Jørgen Nedergaard Larsen; Michael D Spangfort; Kaare Lund; Michael Gajhede
Structure of the house dust mite allergen Der f 2: implications for function and molecular basis of IgE cross-reactivity.
FEBS letters 2005;579(5):1208-12.
2005: Peter Naur; Bente Vestergaard; Lars K Skov; Jan Egebjerg; Michael Gajhede; Jette S Kastrup
Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate.
FEBS letters 2005;579(5):1154-60.
2005: Britt Petersson; Bettina Bryde Nielsen; Hanne Rasmussen; Ingrid K Larsen; Michael Gajhede; Peter E Nielsen; Jette S Kastrup
Crystal structure of a partly self-complementary peptide nucleic acid (PNA) oligomer showing a duplex-triplex network.
Journal of the American Chemical Society 2005;127(5):1424-30.
2004: Anja K Pedersen; G üNther H Peters G; Karin B Møller; Lars F Iversen; Jette S Kastrup
Water-molecule network and active-site flexibility of apo protein tyrosine phosphatase 1B.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 9):1527-34.
2004: Ole Kristensen; Martin Laurberg; Anders Liljas; Jette S Kastrup; Michael Gajhede
Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family.
Biochemistry 2004;43(28):8894-900.
2004: Nikolaj Kulahin; Christina Kasper; Michael Gajhede; Vladimir Berezin; Elisabeth Bock; Jette S Kastrup
Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 3):591-3.
2004: Anja K Pedersen; Xiao-Ling Guo; Karin B Møller; Günther H Peters; Henrik Sune Andersen; Jette S Kastrup; Steen Mortensen; Lars F Iversen; Zhong-Yin Zhang; Niels Peter H Møller
Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.
The Biochemical journal 2004;378(Pt 2):421-33.
2004: Desiree Sprogøe; Lambertus van den Broek; Osman Mirza; Jette S Kastrup; Alphons G J Voragen; Michael Gajhede; Lars K Skov
Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis.
Biochemistry 2004;43(5):1156-62.
2004: H Rasmussen; Tommy Liljefors; B Petersson; P E Nielsen; T Liljefors; Jette S Kastrup
The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals.
Journal of biomolecular structure & dynamics 2004;21(4):495-502.
2003: Vladislav Soroka; Kateryna Kolkova; Jette S Kastrup; Kay Diederichs; Jason Breed; Vladislav V Kiselyov; Flemming M Poulsen; Ingrid K Larsen; Wolfram Welte; Vladimir Berezin; Elisabeth Bock; Christina Kasper
Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion.
Structure (London, England : 1993) 2003;11(10):1291-301.
2003: Marie-Louise Lunn; Anders Hogner; Tine B Stensbøl; James Eric Gouaux; Jan Egebjerg; Jette S Kastrup
Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity.
Journal of medicinal chemistry 2003;46(5):872-5.
2003: Anders Hogner; Jeremy R Greenwood; Tommy Liljefors; Marie-Louise Lunn; Jan Egebjerg; Ingrid K Larsen; James Eric Gouaux; Jette S Kastrup
Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX.
Journal of medicinal chemistry 2003;46(2):214-21.
2002: Christina Kasper; Marie-Louise Lunn; Tommy Liljefors; James Eric Gouaux; Jan Egebjerg; Jette S Kastrup
GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists.
FEBS letters 2002;531(2):173-8.
2002: Anders Hogner; Jette S Kastrup; R Jin; Tommy Liljefors; Mark L Mayer; Jan Egebjerg; Ingrid K Larsen; James Eric Gouaux
Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core.
Journal of molecular biology 2002;322(1):93-109.
2001: Jette S Kastrup; Viggo Linde; Anja K Pedersen; B Stoffer; Lars F Iversen; Ingrid K Larsen; PB Rasmussen; Hans Flodgaard; Sara Bjørn
Two mutants of human heparin binding protein (CAP37): toward the understanding of the nature of lipid A/LPS and BPTI binding.
Proteins 2001;42(4):442-51.
2000: Christina Kasper; Hanne Rasmussen; Jette S Kastrup; S Ikemizu; E Y Jones; Vladimir Berezin; Elisabeth Bock; Ingrid K Larsen
Structural basis of cell-cell adhesion by NCAM.
Nature structural biology 2000;7(5):389-93.
2000: Bettina Bryde Nielsen; Jette S Kastrup; Hanne Rasmussen; Jonas Graversen; Michael Etzerodt; Hans C Thøgersen; Ingrid K Larsen
Crystallization and molecular-replacement solution of a truncated form of human recombinant tetranectin.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 5):637-9.
2000: Viggo Linde; Hans Flodgaard; Jette S Kastrup; Sara Petersen Bjørn
Measurement of apoptosis by the TUNEL method using scintillating microplates.
Analytical biochemistry 2000;280(1):186-8.
2000: Viggo Linde; Sara Petersen Bjørn; Jette S Kastrup; Hans Flodgaard
Lipopolysaccharide affinity measurement by scintillation proximity assay: application to human heparin binding protein.
BioTechniques 2000;28(2):218-20, 222.
1999: Lars F Iversen; Jette S Kastrup; Sara Bjørn; Finn C. Wiberg; Ingrid K Larsen; Hans Flodgaard; PB Rasmussen
Structure and function of the N-linked glycans of HBP/CAP37/azurocidin: crystal structure determination and biological characterization of nonglycosylated HBP.
Protein science : a publication of the Protein Society 1999;8(10):2019-26.
1998: Jette S Kastrup; Bettina Bryde Nielsen; Hanne Rasmussen; Thor L Holtet; Jonas Graversen; Michael Etzerodt; Hans C Thøgersen; Ingrid K Larsen
Structure of the C-type lectin carbohydrate recognition domain of human tetranectin.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 5):757-66.
1998: S Karlsen; Lars F Iversen; Ingrid K Larsen; Hans Flodgaard; Jette S Kastrup
Atomic resolution structure of human HBP/CAP37/azurocidin.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 4):598-609.
1997: Bettina Bryde Nielsen; Jette S Kastrup; Hanne Rasmussen; Thor L Holtet; Jonas Graversen; Michael Etzerodt; Hans C Thøgersen; Ingrid K Larsen
Crystal structure of tetranectin, a trimeric plasminogen-binding protein with an alpha-helical coiled coil.
FEBS letters 1997;412(2):388-96.
1997: Lars F Iversen; M Brzozowski; Sven Hastrup; R Hubbard; Jette S Kastrup; Ingrid K Larsen; L Naerum; L Nørskov-Lauridsen; PB Rasmussen; Lars Thim; Finn C. Wiberg; K Lundgren
Characterization of the allosteric binding pocket of human liver fructose-1,6-bisphosphatase by protein crystallography and inhibitor activity studies.
Protein science : a publication of the Protein Society 1997;6(5):971-82.
1997: Lars F Iversen; Jette S Kastrup; Sara Bjørn; PB Rasmussen; Finn C. Wiberg; Hans Flodgaard; Ingrid K Larsen
Structure of HBP, a multifunctional protein with a serine proteinase fold.
Nature structural biology 1997;4(4):265-8.
1997: Jette S Kastrup; E S Eriksson; H Dalbøge; Hans Flodgaard
X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. comparison with the truncated 146-amino-acid form.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 2):160-8.
1997: Jette S Kastrup; Hanne Rasmussen; Bettina Bryde Nielsen; Ingrid K Larsen; Thor L Holtet; Jonas Graversen; Michael Etzerodt; Hans C Thøgersen
Human plasminogen binding protein tetranectin: crystallization and preliminary X-ray analysis of the C-type lectin CRD and the full-length protein.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 1):108-11.
1996: Lars F Iversen; Jette S Kastrup; Ingrid K Larsen; Sara Bjørn; PB Rasmussen; Finn C. Wiberg; Hans Flodgaard
Crystallization and molecular replacement solution of human heparin binding protein.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 6):1222-3.
1995: Jette S Kastrup; M Pilgaard; Flemming Steen Jørgensen; P E Nielsen; Hanne Rasmussen
Crystallization and preliminary X-ray analysis of a PNA-DNA complex.
FEBS letters 1995;363(1-2):115-7.