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Hitoshi Katai

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Disorders

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Japan

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Kenichi Nakamura; Motoki Ninomiya; Masahiko Ando; Norimasa Fukushima; Seiji Ito; Hitoshi Katai; Junki Mizusawa; Akinori Takagane; Masakazu Takagi; Masanori Terashima; Takaki Yoshikawa; Mitsuru Sasako
A phase III study of laparoscopy-assisted versus open distal gastrectomy with nodal dissection for clinical stage IA/IB gastric Cancer (JCOG0912).
Kazuhiro Yamanoi; Ken Yamazaki; Hiroshi Uchida; Mariko Fukuma; Yae Kanai; Hitoshi Katai; Ryoji Kushima; Michiie Sakamoto
Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in gastric cancer.
Masau Sekiguchi; Haruhisa Suzuki; Hirokazu Taniguchi; Shigetaka Yoshinaga; Hitoshi Katai; Ryoji Kushima; Satoru Nonaka; Ichiro Oda; Makoto Saka; Yutaka Saito
Dehiscence following successful endoscopic closure of gastric perforation during endoscopic submucosal dissection.

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2013: Kenichi Nakamura; Motoki Ninomiya; Masahiko Ando; Norimasa Fukushima; Seiji Ito; Hitoshi Katai; Junki Mizusawa; Akinori Takagane; Masakazu Takagi; Masanori Terashima; Takaki Yoshikawa; Mitsuru Sasako
A phase III study of laparoscopy-assisted versus open distal gastrectomy with nodal dissection for clinical stage IA/IB gastric Cancer (JCOG0912).
Japanese journal of clinical oncology 2013;43(3):324-7.
2013: Kazuhiro Yamanoi; Ken Yamazaki; Hiroshi Uchida; Mariko Fukuma; Yae Kanai; Hitoshi Katai; Ryoji Kushima; Michiie Sakamoto
Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in gastric cancer.
Pathology international 2013;63(1):13-9.
2012: Masau Sekiguchi; Haruhisa Suzuki; Hirokazu Taniguchi; Shigetaka Yoshinaga; Hitoshi Katai; Ryoji Kushima; Satoru Nonaka; Ichiro Oda; Makoto Saka; Yutaka Saito
Dehiscence following successful endoscopic closure of gastric perforation during endoscopic submucosal dissection.
World journal of gastroenterology : WJG 2012;18(31):4224-7.
2012: Daisuke Kubota; Taketo Okubo; Tsuyoshi Saito; Yasuhiro Shimada; Yoshiyuki Suehara; Hitoshi Tsuda; Akihiko Yoshida; Kazuo Kaneko; Hitoshi Katai; Akira Kawai; Kazutaka Kikuta; Tadashi Kondo
Validation study on pfetin and ATP-dependent RNA helicase DDX39 as prognostic biomarkers in gastrointestinal stromal tumour.
Japanese journal of clinical oncology 2012;42(8):730-41.
2012: Yasunori Deguchi; Takeo Fukagawa; Shinji Morita; Masaki Ohashi; Makoto Saka; Hitoshi Katai
Identification of risk factors for esophagojejunal anastomotic leakage after gastric surgery.
World journal of surgery 2012;36(7):1617-22.
2012: Michihiro Ishida; Shinji Morita; Makoto Saka; Hirokazu Taniguchi; Takeo Fukagawa; Hitoshi Katai
Metachronous liver metastasis from early gastric cancer.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012;16(4):837-41.
2012: Hisaharu Oya; Makoto Saka; Haruhisa Suzuki; Hirokazu Taniguchi; Shigetaka Yoshinaga; Takuji Gotoda; Hitoshi Katai; Tetsu Kinjo; Ryoji Kushima; Ichiro Oda
A case of lymph node metastasis following a curative endoscopic submucosal dissection of an early gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2012;15(2):221-5.
2012: Kazutaka Kikuta; Yasuo Beppu; Kazuo Kaneko; Hitoshi Katai; Akira Kawai; Daisuke Kubota; Yasufumi Murakami; Hajime Orita; Tsuyoshi Saito; Koichi Sato; Yasuhiro Shimada; Yoshiyuki Suehara; Yoshiaki Toyama; Hitoshi Tsuda; Takashi Yao; Akihiko Yoshida; Tadashi Kondo
Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumor.
Journal of proteomics 2012;75(4):1089-98.
2012: Tsugumasa Kamata; Hitoshi Katai; Ryoji Kushima; Satoru Nonaka; Haruhisa Suzuki; Hirokazu Taniguchi; Shigetaka Yoshinaga; Takeo Fukagawa; Ichiro Oda
Localized gastric amyloidosis differentiated histologically from scirrhous gastric cancer using endoscopic mucosal resection: a case report.
Journal of medical case reports 2012;6(1):231.
2011: Satoru Nonaka; Ichiro Oda; Teruo Nakaya; Chika Kusano; Haruhisa Suzuki; Shigetaka Yoshinaga; Takeo Fukagawa; Hitoshi Katai; Takuji Gotoda
Clinical impact of a strategy involving endoscopic submucosal dissection for early gastric cancer: determining the optimal pathway.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2011;14(1):56-62.
2011: Norimitsu Tanaka; Hitoshi Katai; Makoto Saka; Shinji Morita; Takeo Fukagawa
Laparoscopy-assisted pylorus-preserving gastrectomy: a matched case-control study.
Surgical endoscopy 2011;25(1):114-8.
2010: Hiroharu Yamashita; Hitoshi Katai
Systemic inflammatory response in gastric cancer.
World journal of surgery 2010;34(10):2399-400.
2010: Masaru Aoki; Makoto Saka; Shinji Morita; Takeo Fukagawa; Hitoshi Katai
Afferent loop obstruction after distal gastrectomy with Roux-en-Y reconstruction.
World journal of surgery 2010;34(10):2389-92.
2010: Takeo Fukagawa; Mitsuru Sasako; Seiji Ito; Hayao Nakanishi; Hisae Iinuma; Shoji Natsugoe; Hitoshi Katai; Tadakazu Shimoda
The prognostic significance of isolated tumor cells in the lymph nodes of gastric cancer patients.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2010;13(3):191-6.
2010: Takeo Fukagawa; Takuji Gotoda; Ichiro Oda; Yasunori Deguchi; Makoto Saka; Shinji Morita; Hitoshi Katai
Stenosis of esophago-jejuno anastomosis after gastric surgery.
World journal of surgery 2010;34(8):1859-63.
2010: Makoto Saka; Shinji Morita; Takeo Fukagawa; Rajwinder Nijjar; Hitoshi Katai
Incidence of pulmonary thromboembolism in gastric cancer surgery using routine thromboprophylaxis.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2010;13(2):117-22.
2010: Shinji Morita; Mitsuru Sasako; Makoto Saka; Takeo Fukagawa; Takeshi Sano; Hitoshi Katai
Correlation between the length of the pyloric cuff and postoperative evaluation after pylorus-preserving gastrectomy.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2010;13(2):109-16.
2010: Norimitsu Tanaka; Hitoshi Katai; Hirokazu Taniguchi; Makoto Saka; Shinji Morita; Takeo Fukagawa; Takuji Gotoda
Trends in characteristics of surgically treated early gastric cancer patients after the introduction of gastric cancer treatment guidelines in Japan.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2010;13(2):74-7.
2010: Hitoshi Katai; S Morita; Makoto Saka; H Taniguchi; Takeo Fukagawa
Long-term outcome after proximal gastrectomy with jejunal interposition for suspected early cancer in the upper third of the stomach.
The British journal of surgery 2010;97(4):558-62.
2010: Takeo Fukagawa; Hitoshi Katai; Makoto Saka; Shinji Morita; Yuko Sasajima; Hirokazu Taniguchi; Takeshi Sano; Mitsuru Sasako
Significance of lavage cytology in advanced gastric cancer patients.
World journal of surgery 2010;34(3):563-8.
2010: Takeshi Fujita; Hitoshi Katai; Shinji Morita; Makoto Saka; Takeo Fukagawa; Takeshi Sano
Short-term outcomes of Roux-en-Y stapled anastomosis after distal gastrectomy for gastric adenocarcinoma.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2010;14(2):289-94.
2010: Kazutaka Kikuta; Masahiro Gotoh; Tatsuo Kanda; Naobumi Tochigi; Tadakazu Shimoda; Tadashi Hasegawa; Hitoshi Katai; Yasuhiro Shimada; Yoshiyuki Suehara; Akira Kawai; Setsuo Hirohashi; Tadashi Kondo
Pfetin as a prognostic biomarker in gastrointestinal stromal tumor: novel monoclonal antibody and external validation study in multiple clinical facilities.
Japanese journal of clinical oncology 2010;40(1):60-72.
2010: Chiharu Tanai; Tetsuya Hamaguchi; Shun-ichi Watanabe; Hitoshi Katai; Naobumi Tochigi; Yasuhiro Shimada
A case of long-term survival after surgical resection of solitary pulmonary metastasis from gastric cancer.
Japanese journal of clinical oncology 2010;40(1):85-9.
2009: Takeo Fukagawa; Hitoshi Katai; Makoto Saka; Shinji Morita; Takeshi Sano; Mitsuru Sasako
Gallstone formation after gastric cancer surgery.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2009;13(5):886-9.
2009: Takeo Fukagawa; Mitsuru Sasako; T Shimoda; Takeshi Sano; Hitoshi Katai; M Saka; G B Mann; M Karpeh; Daniel G Coit; Murray F Brennan
The prognostic impact of isolated tumor cells in lymph nodes of T2N0 gastric cancer: comparison of American and Japanese gastric cancer patients.
Annals of surgical oncology 2009;16(3):609-13.
2009: Taira Kinoshita; Mitsuru Sasako; Takeshi Sano; Hitoshi Katai; Hiroshi Furukawa; Akira Tsuburaya; Isao Miyashiro; Masahide Kaji; Motoki Ninomiya
Phase II trial of S-1 for neoadjuvant chemotherapy against scirrhous gastric cancer (JCOG 0002).
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2009;12(1):37-42.
2008: Chika Kusano; Takuji Gotoda; Christopher J Khor; Hitoshi Katai; Hoichi Kato; Hirokazu Taniguchi; Tadakazu Shimoda
Changing trends in the proportion of adenocarcinoma of the esophagogastric junction in a large tertiary referral center in Japan.
Journal of gastroenterology and hepatology 2008;23(11):1662-5.
2008: Hitoshi Katai; Souya Nunobe; Makoto Saka; Takeo Fukagawa; Takeshi Sano
[Reconstruction after distal gastrectomy].
Nihon Geka Gakkai zasshi 2008;109(5):264-8.
2008: S Morita; Hitoshi Katai; Makoto Saka; T Fukagawa; Takeshi Sano; Mitsuru Sasako
Outcome of pylorus-preserving gastrectomy for early gastric cancer.
The British journal of surgery 2008;95(9):1131-5.
2008: Yukinori Kurokawa; Hitoshi Katai; Haruhiko Fukuda; Mitsuru Sasako
Phase II study of laparoscopy-assisted distal gastrectomy with nodal dissection for clinical stage I gastric cancer: Japan Clinical Oncology Group Study JCOG0703.
Japanese journal of clinical oncology 2008;38(7):501-3.
2008: Makoto Saka; Hitoshi Katai; Takeo Fukagawa; Rajwinder Nijjar; Takeshi Sano
Recurrence in early gastric cancer with lymph node metastasis.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2008;11(4):214-8.
2007: Souya Nunobe; Abuchi Okaro; Mitsuru Sasako; Makoto Saka; Takeo Fukagawa; Hitoshi Katai; Takeshi Sano
Billroth 1 versus Roux-en-Y reconstructions: a quality-of-life survey at 5 years.
International journal of clinical oncology 2007;12(6):433-9.
2007: Yoshihiro Sakamoto; Takeshi Sano; Kazuaki Shimada; Minoru Esaki; Makoto Saka; Takeo Fukagawa; Hitoshi Katai; Tomoo Kosuge; Mitsuru Sasako
Favorable indications for hepatectomy in patients with liver metastasis from gastric cancer.
Journal of surgical oncology 2007;95(7):534-9.
2007: Souya Nunobe; Mitsuru Sasako; Makoto Saka; Takeo Fukagawa; Hitoshi Katai; Takeshi Sano
Symptom evaluation of long-term postoperative outcomes after pylorus-preserving gastrectomy for early gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2007;10(3):167-72.
2007: Mitsuru Sasako; M Saka; Takeo Fukagawa; Hitoshi Katai; Takeshi Sano
Surgical treatment of advanced gastric cancer: Japanese perspective.
Digestive surgery 2007;24(2):101-7.
2007: M Ohashi; Hitoshi Katai; Takeo Fukagawa; Takuji Gotoda; T Sano; Mitsuru Sasako
Cancer of the gastric stump following distal gastrectomy for cancer.
The British journal of surgery 2007;94(1):92-5.
2006: Hitoshi Katai
Function-preserving surgery for gastric cancer.
International journal of clinical oncology 2006;11(5):357-66.
2006: Mitsuru Sasako; Makoto Saka; Takeo Fukagawa; Hitoshi Katai; Takeshi Sano
[Adjuvant chemotherapy using S-1 for curatively resected gastric cancer-the nationwide clinical trial].
Gan to kagaku ryoho. Cancer & chemotherapy 2006;33 Suppl 1():110-6.
2006: T Etoh; Mitsuru Sasako; K Ishikawa; Hitoshi Katai; Takeshi Sano; T Shimoda
Extranodal metastasis is an indicator of poor prognosis in patients with gastric carcinoma.
The British journal of surgery 2006;93(3):369-73.
2006: John Whiting; Takeshi Sano; Makoto Saka; Takeo Fukagawa; Hitoshi Katai; Mitsuru Sasako
Follow-up of gastric cancer: a review.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2006;9(2):74-81.
2005: Hitoshi Katai; Takeshi Sano
Early gastric cancer: concepts, diagnosis, and management.
International journal of clinical oncology 2005;10(6):375-83.
2005: Tsuyoshi Etoh; Hitoshi Katai; Takeo Fukagawa; Takeshi Sano; Ichiro Oda; Takuji Gotoda; Kimio Yoshimura; Mitsuru Sasako
Treatment of early gastric cancer in the elderly patient: results of EMR and gastrectomy at a national referral center in Japan.
Gastrointestinal endoscopy 2005;62(6):868-71.
2005: Souya Nunobe; Takuji Gotoda; Ichiro Oda; Hitoshi Katai; Takeshi Sano; Tadakazu Shimoda; Mitsuru Sasako
Distribution of the deepest penetrating point of minute submucosal gastric cancer.
Japanese journal of clinical oncology 2005;35(10):587-90.
2005: Hitoshi Katai; Kimio Yoshimura; Takeo Fukagawa; Takeshi Sano; Mitsuru Sasako
Risk factors for pancreas-related abscess after total gastrectomy.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2005;8(3):137-41.
2005: Makoto Kubo; Takeshi Sano; Takeo Fukagawa; Hitoshi Katai; Mitsuru Sasako
Increasing body mass index in Japanese patients with gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2005;8(1):39-41.
2005: Makoto Saka; Satvinder S Mudan; Hitoshi Katai; Takeshi Sano; Mitsuru Sasako; Keiichi Maruyama
Pancreaticoduodenectomy for advanced gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2005;8(1):1-5.
2004: Hitoshi Katai; Mitsuru Sasako; Takeshi Sano; Takeo Fukagawa
Gastric cancer surgery in the elderly without operative mortality.
Surgical oncology 2004;13(4):235-8.
2004: Hitoshi Katai; Takeshi Sano; Mitsuru Sasako; Takeo Fukagawa; Makoto Saka
Update on surgery of gastric cancer: new procedures versus standard technique.
Digestive diseases (Basel, Switzerland) 2004;22(4):338-44.
2004: Mazin E Sayegh; Takeshi Sano; Simon Dexter; Hitoshi Katai; Takeo Fukagawa; Mitsuru Sasako
TNM and Japanese staging systems for gastric cancer: how do they coexist?
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2004;7(3):140-8.
2003: Hitoshi Katai; Takeshi Sano; Takeo Fukagawa; H Shinohara; Mitsuru Sasako
Prospective study of proximal gastrectomy for early gastric cancer in the upper third of the stomach.
The British journal of surgery 2003;90(7):850-3.
2001: Takeo Fukagawa; Mitsuru Sasako; G B Mann; T Sano; Hitoshi Katai; K Maruyama; Y Nakanishi; T Shimoda
Immunohistochemically detected micrometastases of the lymph nodes in patients with gastric carcinoma.
Cancer 2001;92(4):753-60.
2001: Mitsuru Sasako; Tsuyoshi Sano; Hitoshi Katai
[Informed consent for surgical treatment of gastric cancer].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 4():565-9.
2001: Tsuyoshi Sano; Hitoshi Katai; Mitsuru Sasako; K Maruyama
[Prevention of gastric stump carcinoma].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 4():506-10.
2001: Hitoshi Katai; Mitsuru Sasako; Tsuyoshi Sano; K Maruyama
[Surgical treatment for gastric cancer in western countries].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 4():281-6.
2001: T Yamaguchi; Takeshi Sano; Hitoshi Katai; Mitsuru Sasako; K Maruyama
Node-positive mucosal gastric cancer: a follow-up study.
Japanese journal of clinical oncology 2001;31(4):153-6.
2000: Makoto Saka; Mitsuru Sasako; Hitoshi Katai; Takeshi Sano
[Current status and problem of adjuvant chemotherapy for curatively resected gastric cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2000;27(13):2033-42.
2000: Mitsuru Sasako; Hitoshi Katai; Takeshi Sano; K Maruyama
Management of complications after gastrectomy with extended lymphadenectomy.
Surgical oncology 2000;9(1):31-4.
2000: Takeshi Sano; Hitoshi Katai; Mitsuru Sasako; K Maruyama
The management of early gastric cancer.
Surgical oncology 2000;9(1):17-22.
2000: Hitoshi Katai; K Yoshimura; K Maruyama; Mitsuru Sasako; T Sano
Evaluation of the New International Union Against Cancer TNM staging for gastric carcinoma.
Cancer 2000;88(8):1796-800.
1999: K Maruyama; Mitsuru Sasako; T Kinoshita; T Sano; Hitoshi Katai
Can sentinel node biopsy indicate rational extent of lymphadenectomy in gastric cancer surgery? Fundamental and new information on lymph-node dissection.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 1999;384(2):149-57.
1999: Mitsuru Sasako; T Sano; Hitoshi Katai
[Practice guidelines in western countries].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(5):602-8.
1998: Y Kanemitsu; H Kondo; Hitoshi Katai; H Nakayama; H Asamura; R Tsuchiya; T Naruke
Surgical resection of pulmonary metastases from gastric cancer.
Journal of surgical oncology 1998;69(3):147-50.
1998: K Maruyama; Mitsuru Sasako; T Kinoshita; T Sano; Hitoshi Katai; M Hada; A Schmidt-Matthiesen; O Dahl
Should systematic lymph node dissection be recommended for gastric cancer?
European journal of cancer (Oxford, England : 1990) 1998;34(10):1480-9.
1998: K Maruyama; Mitsuru Sasako; T Sano; Hitoshi Katai; Taira Kinoshita; Takeo Fukagawa
[TNM classification: cancer of the stomach].
Gan to kagaku ryoho. Cancer & chemotherapy 1998;25(11):1793-9.
1998: Hitoshi Katai; Mitsuru Sasako; Takeshi Sano; K Maruyama
The outcome of surgical treatment for gastric carcinoma in the elderly.
Japanese journal of clinical oncology 1998;28(2):112-5.
1998: Hitoshi Katai; Mitsuru Sasako; T Sano; K Maruyama
Surgical treatment for gastric leiomyosarcoma.
Annales chirurgiae et gynaecologiae 1998;87(4):293-6.
1997: Takeshi Sano; Mitsuru Sasako; Hitoshi Katai; K Maruyama
Amylase concentration of drainage fluid after total gastrectomy.
The British journal of surgery 1997;84(9):1310-2.
1997: T Sano; Mitsuru Sasako; T Kinoshita; Hitoshi Katai; K Maruyama; T Takenaka; Y Nakanishi
Total gastrectomy for primary gastric lymphoma at stages IE and IIE: a prospective study of fifty cases.
Surgery 1997;121(5):501-5.
1997: T Sano; Mitsuru Sasako; Hitoshi Katai; K Maruyama
Radical lymphadenectomy in the management of early gastric cancer.
The British journal of surgery 1997;84(4):581-2.
1997: Hitoshi Katai; Mitsuru Sasako; Takeshi Sano; K Maruyama
Wedge resection of the stomach for gastric leiomyosarcoma.
The British journal of surgery 1997;84(4):560-1.
1997: T Takenaka; K Maruyama; T Kinoshita; M Sasako; T Sano; Hitoshi Katai; Y Matsuno
A prospective study of surgery and adjuvant chemotherapy for primary gastric lymphoma stage II.
British journal of cancer 1997;76(11):1484-8.
1996: N Noda; T Sano; Kuniaki Shirao; H Ono; Hitoshi Katai; Mitsuru Sasako; K Maruyama
A case of bone marrow recurrence from gastric carcinoma after a nine-year disease-free interval.
Japanese journal of clinical oncology 1996;26(6):472-5.
1996: K Maruyama; Mitsuru Sasako; T Kinoshita; T Sano; Hitoshi Katai
Surgical treatment for gastric cancer: the Japanese approach.
Seminars in oncology 1996;23(3):360-8.
1996: Hitoshi Katai; Mitsuru Sasako; T Sano; K Maruyama
Gastric carcinoma in young adults.
Japanese journal of clinical oncology 1996;26(3):139-43.
1995: K Maruyama; Mitsuru Sasako; T Kinoshita; T Sano; Hitoshi Katai; K Okajima
Pancreas-preserving total gastrectomy for proximal gastric cancer.
World journal of surgery 1995;19(4):532-6.
1994: Mitsuru Sasako; T Sano; Hitoshi Katai; K Okajima; K Maruyama
[Overview of clinical trials on adjuvant chemotherapy for curatively resected gastric cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1994;21 Suppl 3():384-94.
1994: P Ríos; K Maruyama; M Sasako; T Sano; Hitoshi Katai
[The current situation and treatment strategy for gastric cancer at the National Cancer Center of Tokyo, Japan].
Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú 1994;14(3):197-203.